JOURNAL READINGNeuroregeneration and dementia : new treatment optionsNeuroregeneration and dementia: new treatment optionsSmaranda Ioana Mitran,Bogdan Catalin,Veronica Sfredel, Tudor-Adrian BalseanuMitran et al. Journal of Molecular Psychiatry 20!" #2Journal rea$in% fro& Me$ical 'tu$ents of Isla&ic 'ultan A%un% Uni(ersity'u)er(isor $r. 'a*ar 'ire%ar" ').+JMa%elan%" 20th Dece&*er 20!,orres)on$ence# a$rian.*alseanu-.e*&ail.u&fc(.roDe)art&ent of /unctional 'ciences" Uni(ersity of Me$icine an$ Phar&acy" ,raio(a" Ro&ania,enter of ,linical an$ E0)eri&ental Me$icine" Uni(ersity of Me$icine an$ Phar&acy" ,raio(a" Ro&aniaAbstractAbstractIntroductionIntroductionReviewReviewConclusionConclusionABSTRACTphysiological aging all the changes that occur in organism with old agedementialearning defcitmemory losslow attention spanimpairment of speechpoor problem solving skillsdementiaINTRODUCTIONneurodegenerationneurodegenerationcelular and molecularcelular and molecularnew therapeutic dementia in elderynew therapeutic dementia in elderyneuroregenerationneuroregenerationbrain ageingbrain ageingNUROR!NRATION AND A!IN!declining abilityto respondto dierent typesdeclining abilityto respondto dierent typesstressstressdiseasediseasehomeostatic imbalancehomeostatic imbalancemost important risk factormost important risk factorbrain ageingbrain ageingbrain degenerationbrain degenerationage!related cognitive disordersage!related cognitive disordersstructuresneuron " gliastructuresneuron " gliafunctions neuron " gliafunctions neuron " gliaapoptosisapoptosisbrain ageingbrain ageingreductioncommunicationreductioncommunicationreductionmemory functionreductionmemory functionpoor recovery after strokepoor recovery after strokeneurodegenerationneurodegenerationproliferation neural progenitorproliferation neural progenitordierentiation neural progenitordierentiation neural progenitorbrain ageingbrain ageingnewborn death neuronsnewborn death neuronsremoval of the aetiological factorsremoval of the aetiological factorsin#ammatory responsein#ammatory responseto impede the degeneration of cellsto impede the degeneration of cellsto restore the neural cells or their networkto restore the neural cells or their networkbrain!repairing pathwaysbrain!repairing pathwaysbrain damagebrain damagesuperposition of distinctive processessuperposition of distinctive processesneurogenesisneurogenesisneuroplasticityneuroplasticityneurorestorationneurorestorationneuroregenerationneuroregenerationcentral nervous system tissuecentral nervous system tissueneural network architectureneural network architecturemorfological perspective neuroregenerationmorfological perspective neuroregenerationfunctional perspective neuroregenerationfunctional perspective neuroregenerationrestorative processrestorative processA$%I&$ A&' '%(%&TIAnot e)plained by delirium or ma*or psychiatric disordernot e)plained by delirium or ma*or psychiatric disorderinterfere with one+s ability to function with usual activitiesinterfere with one+s ability to function with usual activitiesdementiaac"uiring defense from dietar# antio$idantsalcohol abuseunhealthy eating smokingstrokedementiaearly onset dementiaearly onset dementialate onset dementialate onset dementiabefore ,- yearbefore ,- yearcommon among the geriatric populationcommon among the geriatric populationdisorientated in time. place and identitydisorientated in time. place and identity