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Transcript of Neuregulin 1 allosterically enhances the anti-tumor ......,5&0 ,QVWLWXW GH 5HFKHUFKH HQ &DQFpURORJLH...

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in vivo

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in vivo

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γ

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μ

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NRG1α, NRG1β, EGF HPRT

HPRT

in vivo

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in vivo

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vs vs

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in vivo

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in situ

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in vitro

in vivo

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β β

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Published OnlineFirst May 15, 2017.Mol Cancer Ther   Christophe Le Clorennec, Hervé Bazin, Olivier Dubreuil, et al.   its binding to HER3the non-competing anti-HER3 antibody 9F7-F11 by increasing Neuregulin 1 allosterically enhances the anti-tumor effects of

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