Neoplasia Introduction
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Neoplasia Introduction . By DR.HALA BADAWI LECTURER OF PATHOLOGY . Neoplasia. Characteristics . Gross picture. BENIGN. MALIGNANT. Not capsulated Areas of necrosis and haemorhage In solid organs : fixed irregular mass with ill defined borders - PowerPoint PPT Presentation
Transcript of Neoplasia Introduction
Neoplasia Introduction
ByDR.HALA BADAWILECTURER OF PATHOLOGY
Neoplasia Introduction NeoplasiaCharacteristics
BENIGNMALIGNANTGross picture Spherical or ovoid in shape Mostly capsulated No haemorrhage or necrosis Not capsulated Areas of necrosis and haemorhage In solid organs: fixed irregular mass with ill defined bordersIn body surfaces: Polypoid (fungating), infiltrating or ulcerative
3NeoplasiaCharacteristics
BENIGNMALIGNANTMicroscopic pictureCytological Features Cytological atypia (anaplasia) Change in cellular morphologyCellular polymorphism, nuclear hyperchromatism, mitoses & tumour giant cells Change in cellular pattern (Loss of polarity)Cells like the original cell Microscopic Features (ANAPLASIA) PleomorphismHyperchromatic nucleiMultiple large nucleoliHigh N/C ratioHigh mitotic rateAbnormal mitosis Tumor giant cells
Neoplasia
