Neglected tropical diseases - WHO · dracunculiasis (guinea-WOrm disease) Countries endemic for...

Neglected tropical diseasesA stAtisticAl updAte – lAtest dAtA AvAilAble

*** A stAtisticAl updAte – lAtest dAtA AvAilAble

© World Health Organization 2014All rights reserved. Publications of the World Health Organization are available on the WHO web site (www.who.int) or can be purchased from WHO Press, World Health Organization, 20 Avenue Appia, 1211 Geneva 27, Switzerland (tel.: +41 22 791 3264; fax: +41 22 791 4857; e-mail: [email protected]). Requests for permission to reproduce or translate WHO publications – whether for sale or for non-commercial distribution – should be addressed to WHO Press through the WHO web site (www.who.int/about/licensing/copyright_form/en/index.html).

The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement.

The mention of specific companies or of certain manufacturers’ products does not imply that they are endorsed or recommended by the World Health Organization in preference to others of a similar nature that are not mentioned. Errors and omissions excepted, the names of proprietary products are distinguished by initial capital letters.

All reasonable precautions have been taken by the World Health Organization to verify the information contained in this publication. However, the published material is being distributed without warranty of any kind, either expressed or implied. The responsibility for the interpretation and use of the material lies with the reader. In no event shall the World Health Organization be liable for damages arising from its use.

Maps, design, layout and figures: WHO/HTM/NTD

1 *** A stAtisticAl updAte – lAtest dAtA AvAilAble

Buruli ulcer

Distribution of Buruli ulcer, worldwide, 2013

The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. © WHO 2014. All rights reserved

Data Source: World Health OrganizationMap Production: Control of Neglected Tropical Diseases (NTD)World Health Organization

Distribution of Buruli ulcer, worldwide, 2013

< 100

Not applicable

Previously reported cases100 499

500 999

Number of reported cases, 2013> 1 000 No cases reported

2005 2006 2007 2008 2009 2010 2011 2012 2013

AFR 4 674 5 265 4 935 5 079 5 029 4 846 3 841 3 104 2 543 AMR 2 2 2 8 2 7 3 2 3 EMR 24 38 8 3 5 4 WPR 48 73 90 66 48 56 161 105 84 Global 4 748 5 378 5 035 5 156 5 084 4 913 4 005 3 211 2 630

AFR–African Region / AMR–Region of the Americas / EMR–Eastern Mediterranean Region / WPR–Western Pacific Region

Number of Buruli ulcer cases reported to WHO, by region, 2005–2013

6 000

5 000

4 000

3 000

2 000

1 000

0 2005 2006 2007 2008 2009 2010 2011 2012 2013

Year

African Region Region of the Americas Eastern Mediterranean Region South-East Asia Region Western Pacific Region

Num

ber

of n

ew c

ases

det

ecte

d

2 neglected tropical diseases *** *** A stAtisticAl updAte – lAtest dAtA AvAilAble

cHagas disease

Estimated number of T. cruzi infected cases< 900

90 000 899 999Not applicable

No data available900 89 999

> 900 000

Distribution of Chagas disease cases, based on official estimates, worldwide, 2010–2013

Estimated prevalence of Chagas disease, by official source, 1960–2014

30

25

20

15

10

5

0

Mill

ions

1960 1976 1981 1984 1985 1990 1991 1992 1992 1994 1999 1999 2000 2006 2006 2010 2013 2014

Year and source

Latin American Initiatives NEC Initiative

Est

imat

ed p

reva

lenc

e

WH

O

WH

O

WH

O

PA

HO

Was

lh

WH

O

WH

O

WH

O

WH

O

PA

HO

Sch

mun

is

Sch

mun

is

Sch

mun

is

Wor

ld B

ank/

DC

PP

PA

HO

/WH

O

WH

O

WH

O

WH

O

DCPP: Disease Control Priorities Project; NEC: non-endemic countries


Distribution of countries or areas at risk of dengue transmission, worldwide, 2013



Distribution of countries or areas at risk of dengue transmission, worldwide, 2013

Not applicable

Countries or areas at risk of dengue transmission

January isotherm

July isotherm

10 °C

10 °C

The contour lines of the January and July isotherms indicate areas at risk, defined by the geographical limits of the northern and southern hemispheres for year-round survival of Aedes aegypti, the principal mosquito vector of dengue viruses

Number of dengue cases reported to WHO, by region, 1995–2013

3.5

3

2.5

2

1.5

1

0.5

0

Mill

ions

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013

Year

Eastern Mediterranean Region Region of the Americas South-East Asia Region Western Pacific Region

Num

ber

of c

ases

rep

orte

d

dengue


Number of dengue deaths reported to WHO, worldwide, 2000–2013

4 500

4 000

3 500

3 000

2 500

2 000

1 500

1 000

500

0 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013

Year

Num

ber

of d

eath

s re

port

ed


dracunculiasis (guinea-WOrm disease)

Not applicableCountries endemic for dracunculiasis

1989 2013

Countries endemic for dracunculiasis, 1989 and 2013

Number of dracunculiasis cases reported to WHO, by month, 2012–2014

140

120

100

80

60

40

20

0 Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

Num

ber

of c

ases

rep

orte

d

month 2012 2013 2014

a Data for 2014 are provisional up to September.

Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec

2012 2 5 55 82 125 128 71 32 22 14 4 2 2013 1 2 4 29 33 23 17 12 13 5 7 2 2014 1 1 4 5 5 11 25 22 26


Status of global certification of dracunculiasis eradication, 2013

Not applicable

Other countries and territories certified free of dracunculiasis

Countries and territories not known to have dracunculiasis but yet to be certified

Previously endemic countries certified free of dracunculiasisCountries in the precertification stage

Countries currently endemic for dracunculiasis


ecHinOcOccOsis

Distribution of Echinococcus granulosus and cystic echinococcosis, worldwide, 2012



Distribution of Echinococcus granulosus and cystic echinococcosis, worldwide,2012

Not applicable

Probably absentSuspected

Present

Highly endemic areas Rare/sporadic


endemic trepOnematOses

Distribution of yaws, worldwide, 2013



Distribution of yaws, worldwide, 2008-2013

≥ 10 000

1 000–9 999

< 1 000

Transmission interrupted

Not applicable

Previously endemic (current status unknown)

No previous history of yaws

Number of reported cases of yaws, 2008-2013, latest year available

Number of yaws cases reported to WHO, 2008–2013

90

80

70

60

50

40

30

20

10

0

Tho

usan

ds

2008 2009 2010 2011 2012 2013

Year

Num

ber

of c

ases

rep

orte

d

2008 2009 2010 2011 2012 2013

Global 56 223 69 467 80 226 51 101 49 375 58 915

Number of cases reported


Distribution of clonorchiasis, worldwide, latest year available



Distribution of clonorchiasis, worldwide, latest year available

Not applicable

No data available

Countries with reported cases of Clonorchis sinensis infection

Distribution of opisthorchiasis, worldwide, latest year available



Distribution of opisthorchiasis, worldwide, latest year available

Not applicable

No data available

Countries with reported cases of Opisthorchis viverrini and Opisthorchis felineus infections

Countries with reported cases of Opisthorchis felineus infection

Countries with reported cases of Opisthorchis viverrini infection

FOOdBOrne trematOdiases


Distribution of fascioliasis, worldwide, latest year available



Distribution of fascioliasis, worldwide, latest year available

Not applicable

No data available

Countries with reported cases of Fasciola spp. infection

Distribution of paragonimiasis, worldwide, latest year available



Distribution of paragonimiasis, worldwide, latest year available

Not applicable

No data available

Countries with reported cases of Paragonimus spp. infection


Distribution of human African trypanosomiasis (T.b. gambiense), worldwide, 2013



Distribution of human African trypanosomiasis (T.b.gambiense), worldwide, 2013

0 cases reported

Not applicable

Non T.b.gambiense endemic countries

Endemic countries (no data available)

< 100

100 1 000

Number of reported cases, 2013

> 1 000

Distribution of human African trypanosomiasis (T.b. rhodesiense), worldwide, 2013



Distribution of human African trypanosomiasis (T.b.rhodesiense), worldwide, 2013

0 cases reported

Not applicable

Non T.b.rhodesiense endemic countries

Endemic countries (no data available)< 100

Number of reported cases, 2013

Human aFrican trYpanOsOmiasis (sleeping sickness)


Number of human African trypanosomiasis cases reported to WHO,1990–2013

40

35

30

25

20

15

10

5

0

Tho

usan

ds

1990 1992 1994 1996 1998 2000 2002 2004 2006 2008 2010 2012

Year

T.b. gambiense T.b. rhodesiense

Num

ber

of c

ases

rep

orte

d

1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001

12 756 10 987 14 088 16 607 23 266 23 671 28 736 36 585 37 385 27 862 25 865 26 117 1933 1219 1147 831 711 935 591 592 606 619 709 755

2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013

23 836 19 963 17 130 15 644 11 382 10 473 10 388 9 685 6 978 6 637 7 106 6 228 617 536 552 710 453 305 259 190 156 113 110 86

T.b. gambiense T.b. rhodesiense


leisHmaniases

Distribution of visceral leishmaniasis, worldwide, 2012



Status of endemicity of visceral leishmaniasis, worldwide, 2012

0

< 100 Not applicable

No data available

No autochthonous cases reported

100 1 000

> 1 000

Number of new cases reported, 2012

Distribution of cutaneous leishmaniasis, worldwide, 2012



Status of endemicity of cutaneous leishmaniasis, worldwide, 2012

0

< 1 000 Not applicable

No data available

No autochthonous cases reported

1 000 4 999

> 5 000

Number of new cases reported, 2012


Number of cutaneous leishmaniasis cases reported to WHO, by region, 2003–2012

250

200

150

100

50

0

Tho

usan

ds

2003 2004 2005 2006 2007 2008 2009 2010 2011 2012

Year

African Region Region of the Americas Eastern Mediterranean Region European Region Western Pacific Region South-East Asia Region

Num

ber

of c

ases

rep

orte

d

2003 2004 2005 2006 2007 2008 2009 2010 2011 2012

AFR 22 292 17 404 31 159 15 304 7 052 8 513 10 666 10 173 14 159 9 057 AMR 65 909 63 397 71 866 65 581 62 653 55 558 60 326 61 311 56 794 50 060 EMR 77 017 98 729 97 344 93 910 94 425 99 466 124 143 121 403 139 363 131 865 EUR 3 758 5 305 2 967 2 717 2 658 2 421 2 271 3 150 10 3 SEAR 232 248 386 405 540 572 513 148 0 0 WPR 0 0 0 0 0 1 3 0 0 0 Total 169 208 185 083 203 722 177 917 167 328 166 531 197 922 196 185 210 326 190 985

AFR–African Region / AMR–Region of the Americas / EMR–Eastern Mediterranean Region / EUR–European Region / SEAR–South-East Asia Region / WPR–Western Pacific Region

Number of visceral leishmaniasis cases reported to WHO, by region, 2003–2012

African Region Region of the Americas Eastern Mediterranean Region European Region Western Pacific Region South-East Asia Region

2003 2004 2005 2006 2007 2008 2009 2010 2011 2012

AFR 8 610 6 032 6 623 3 965 2 652 2 584 3 231 11 270 14 458 8 126 AMR 3 166 3 783 3 753 3 825 3 780 4 003 3 878 3 952 4 005 3 214 EMR 10 230 6 289 6 165 3 729 4 100 5 339 7 265 9 107 7 029 4 924 EUR 776 868 864 771 890 669 363 556 340 131 SEAR 26 556 31 987 41 158 50 091 50 900 39 813 29 333 32 898 37 260 23 048 WPR 0 351 335 294 382 529 539 402 293 218 Total 49 338 49 310 58 898 62 675 62 704 52 937 44 609 58 185 63 385 39 661

AFR–African Region / AMR–Region of the Americas / EMR–Eastern Mediterranean Region / EUR–European Region / SEAR–South-East Asia Region / WPR–Western Pacific Region

70

60

50

40

30

20

10

0

Tho

usan

ds

2003 2004 2005 2006 2007 2008 2009 2010 2011 2012

Year

Num

ber

of c

ases

rep

orte

d


2003 2004 2005 2006 2007 2008 2009 2010 2011 2012

Bangladesh 6 113 5 920 6 892 9 379 4 932 4 840 4 293 3 800 3 376 1 902 Brazil 2 971 3 580 3 597 3 651 3 604 3 852 3 693 3 716 3 840 3 118 Ethiopia NA 1 403 2 585 2 375 1 579 1 356 1 083 1 936 2 032 2 500 India 18 214 24 479 32 803 39 173 44 533 33 598 24 213 28 382 33 155 20 571 South Sudan 7 722 3 777 3 141 1 117 758 582 1 907 9 166 11 862 5 012 Sudan 704 2 619 3 713 1 827 2 788 3 310 4 880 6 957 5 226 3 165 Top 6 HBC 42 324 41 778 52 731 57 522 58 194 47 538 40 069 53 957 59 491 36 268

Top six high-burden countries for visceral leishmaniasis, 2003–2012

Top six high-burden countries (HBC) Bangladesh India Nepal

70

60

50

40

30

20

10

0

Tho

usan

ds

2003 2004 2005 2006 2007 2008 2009 2010 2011 2012

Year

Num

ber

of c

ases

rep

orte

d


New case-detection rates for leprosy, data reported to WHO as of January 2014



Leprosy new case detection rates, data reported to WHO as of January 2014

Not applicable

Not reported

< 1

1.0 10.0

New case detection rates (per 100 000 population)> 10

0 cases reported

Registered cases of leprosy, data reported to WHO as of January 2014



Leprosy prevalence rates, data reported to WHO as of January 2014

Not applicable

Not reported

< 1

1.0 2.0

Registered cases (per 10 000 population)> 2

0 cases reported

leprOsY


Number of new leprosy cases reported to WHO, by region, 2006–2013

300

250

200

150

100

50

0

Tho

usan

ds

2006 2007 2008 2009 2010 2011 2012 2013

Year

African Region Region of the Americas Eastern Mediterranean Region South-East Asia Region Western Pacific Region

Num

ber

of n

ew c

ases

rep

orte

d

2006 2007 2008 2009 2010 2011 2012 2013

AFR 34 480 34 468 29 814 28 935 25 345 20 213 20 599 20 911 AMR 47 612 42 135 41 891 40 474 37 740 36 832 36 178 33 084 EMR 3 261 4 091 3 938 4 029 4 080 4 357 4 235 1 680 SEAR 174 118 171 576 167 505 166 115 156 254 160 132 166 445 155 385 WPR 6 190 5 863 5 859 5 243 5 055 5 092 5 400 4 596 Total 265 661 258 133 249 007 244 796 228 474 226 626 232 857 215 656

AFR–African Region / AMR–Region of the Americas / EMR–Eastern Mediterranean Region / SEAR–South-East Asia Region / WPR–Western Pacific Region


Distribution and status of delivering preventive chemotherapy for lymphatic filariasis, worldwide, 2012



Distribution and status of preventive chemotherapy for lymphatic filariasis, worldwide, 2012

Not applicable

Non-endemic countries and territories

Endemic countries and territories where implementation of preventive chemotherapy has not started

Endemic countries and territories where the target was achieved and implementation stopped

Endemic countries and territories implementing preventive chemotherapy

Number of people treated and global coverage of preventive chemotherapy for lymphatic filariasis, by WHO region, 2008–2012

700

600

500

400

300

200

100

0

Mill

ions

2008 2009 2010 2011 2012

Year

African Region Region of the Americas Eastern Mediterranean Region South-East Asia Region Western Pacific Region European Rgeion Global coverage

Num

ber

of p

eopl

e tr

eate

d

Glo

bal c

over

age

(%)

50

45

40

35

30

25

20

15

10

5

0

lYmpHatic Filariasis


OncHOcerciasis (river Blindness)

Distribution of onchocerciasis, worldwide, 2012



Distribution of onchocerciasis, worldwide, 2013

Not applicable

Non-endemic countries

Endemic countries (former OCP countries)

Hypo-endemic (prevalence < 20%)

Meso-or hyper-endemic (prevalence > 20%)

Number of people treated and global coverage of preventive chemotherapy for onchocerciasis, by WHO region, 2008–2012

120

100

80

60

40

20

0

Mill

ions

2008 2009 2010 2011 2012

Year

African Region Region of the Americas Eastern Mediterranean Region Global coverage

Num

ber

of p

eopl

e tr

eate

d

Glo

bal c

over

age

(%)

90

80

70

60

50

40

30

20

10

0


raBies

Distribution of risk to humans of contracting rabies, worldwide, 2013



Distribution of risk levels for humans contacting rabies, worldwide, 2013

Not applicable

No risk

Low risk

Moderate risk

High risk

No data available

Number of human rabies cases compared with animal rabies cases in KwaZulu-Natal (South Africa), 2007–2014

7

6

5

4

3

2

1

0 2007 2008 2009 2010 2011 2012 2013 2014

Year

Human rabies Animal rabies

Num

ber

of h

uman

dea

ths

repo

rted

Num

ber

of a

nim

al r

abie

s ca

ses

500

450

400

350

300

250

200

150

100

50

0


Number of humans potentially exposed to rabies and presenting for post-exposure prophylaxis, 2010–2013

100

80

60

40

20

0 January January January January 2010 2011 2012 2013

Year

Human rabies

Per

cent

age

of in

trad

erm

al a

dmin

istr

atio

n us

e ve

rsus

intr

amus

cula

r


Distribution of schistosomiasis, worldwide, 2012



Distribution of schistosomiasis, worldwide, 2012

Not applicable

Non-endemic countries

Countries requiring evaluation of schistosomiasis statusin order to verify if interruption of transmission has been achieved

Low (prevalence < 10%)

Moderate (prevalence 10% 49%)

High (prevalence > 50%)

Number of people treated and global coverage with preventive chemotherapy for schistosomiasis, by WHO region, 2008–2012

45

40

35

30

25

20

15

10

5

0

Mill

ions

2008 2009 2010 2011 2012

Year

African Region Region of the Americas Eastern Mediterranean Region South-East Asia Region Western Pacific Region European Global coverage

Num

ber

of p

eopl

e tr

eate

d

Glo

bal c

over

age

(%)

16

14

12

10

8

6

4

2

0

scHistOsOmiasis


Distribution of soil-transmitted helminthiases and proportion of children (aged 1–14 years) in eeach endemic country requiring preventive chemotherapy for the diseases, worldwide, 2012



Proportion of children (1-14 years of age) in the country requiring preventive chemotherapy (PC) for soil-transmitted helminthiases, worldwide, 2012

Not applicable

Not required

No data available

< 1/3

1/3 2/3

> 2/3

Number of preschool-aged children treated and global coverage of preventive chemotherapy for soil-transmitted helminthiases, by WHO region, 2008–2012

140

120

100

80

60

40

20

0

Mill

ions

2008 2009 2010 2011 2012

Year

African Region Region of the Americas Eastern Mediterranean Region South-East Asia Region Western Pacific Region European Region Global coverage

Num

ber

of p

eopl

e tr

eate

d

Glo

bal c

over

age

(%)

40

35

30

25

20

15

10

5

0

sOil-transmitted HelmintHiases


Number of school-aged children treated and global coverage of preventive chemotherapy for soil-transmitted helminthiases, by WHO region, 2008–2012

300

250

200

150

100

50

0

Mill

ions

2008 2009 2010 2011 2012

Year

African Region Region of the Americas Eastern Mediterranean Region South-East Asia Region Western Pacific Region European Global coverage

Num

ber

of p

eopl

e tr

eate

d

Glo

bal c

over

age

(%)

40

35

30

25

20

15

10

5

0


taeniasis and (neurO)cYsticercOsis

Countries and areas at risk of cysticercosis, 2012



Countries and areas at risk of cysticercosis, 2012

Not applicable

No data available

Imported cases (possible human cysticercosis transmission)

Suspected endemic

Endemic (full life-cycle)


tracHOma

Distribution of trachoma, worldwide, 2012



Distribution of trachoma, worldwide, 2012

Not applicable

Countries or areas under surveillance

Countries or areas endemic for blinding trachoma

Number of people treated and global coverage of azithromycin for trachoma, by WHO region, 2008–2012

60

50

40

30

20

10

0

Mill

ions

2008 2009 2010 2011 2012

Year

African Region Region of the Americas Eastern Mediterranean Region South-East Asia Region Western Pacific Region Global coverage

Num

ber

of p

eopl

e tr

eate

d

Glo

bal o

cver

age

(%)

25

20

15

10

5

0

Neglected tropical diseases - WHO · dracunculiasis (guinea-WOrm disease) Countries endemic for...

Documents

Transcript of Neglected tropical diseases - WHO · dracunculiasis (guinea-WOrm disease) Countries endemic for...