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    Free for all? Patent lawscan make or breakgeneric drug production.

    India is the

    pharmacy for the

    developing

    world.

    Ellen 't Hoen

    MSF's Campaign for

    Access to Essential

    Medicines

    Published online 15 January 2007 | Nature | doi:10.1038/news070115-1

    News

    Petition aims to maintain cheap drugs

    Court case in India threatens to derail generic medicines.

    Apoorva Mandavilli

    The international humanitarian group Doctors Without Borders

    (Mdecins Sans Frontires, or MSF) is ramping up their fight against

    the Swiss drug giant Novartis, urging the company to drop a lawsuit

    that could make it much more difficult for Indian companies to

    produce cheap, generic drugs.

    With the case expected to come up for hearing on 29 January, MSF is

    pumping up efforts to collect signatures on a petition against the suit.

    Already they have tens of thousands of names, but are aiming to get

    many more. A win for the pharmaceutical company, they say, would

    deprive the world's poorest people of affordable medicines.

    Indian companies are known for making low-cost copies of expensive

    medicines, particularly AIDS drugs. More than half of the

    antiretroviral drugs used in developing countries, and about 80% of

    those provided by MSF, are made by Indian companies. "India is the pharmacy for the developing

    world," says Ellen 't Hoen, director of policy advocacy for MSF's Campaign for Access to Essential

    Medicines. "We largely depend on India."

    India's laws currently don't allow drug companies to patent products that

    are seen to be simply new derivatives or combinations of existing drugs.

    This frees up local companies to do a booming trade in inexpensive copies

    of the non-patented formulations.

    In January 2006, Novartis was denied a patent by a court in the southern

    Indian city of Chennai for their cancer drug Glivec, after the drug was

    deemed a variation of a previously patented substance.

    But Novartis disagrees with the decision. In May, the company filed

    petitions against the Indian government and the Indian Patent Office, claiming that the rulingviolates World Trade Organization rules on patents.

    MSF and other activist groups fear that if Novartis wins, an increase in patented drugs in India

    will mean fewer generics for all.

    All for one

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    Other companies have remained on the sidelines of this court case, but a victory for Novartis

    would benefit all multinational companies, says 't Hoen. "I think they're all watching because none

    of them are happy with that part of the law," she says.

    So far, at least, Novartis is standing firm. "We don't agree with the petition," says Paul Herrling,

    head of corporate research for Novartis. "It's our democratic right to appeal to a court."

    The last time MSF took on such a high-profile fightwas in 2001, in response to 39 companies taking the

    South African government to court to prevent the

    country from importing cheap AsIDS drugs. "This

    looks very similar," says 't Hoen.

    In that case, MSF collected nearly 300,000 signatures

    from more than 130 countries. Following public outcry,

    the companies eventually backed down and dropped

    their court case.

    But there have been other instances when companies

    have won, notes James Love, director of the Consumer

    Project on Technology in Washington DC. "Sometimes

    protest works, sometimes it doesn't," Love says. "But there's only so much heat the companies can

    take."

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