Natural Treatments for Arthritis
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Transcript of Natural Treatments for Arthritis
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NATURAL TREATMENTS FOR ARTHRITISIndra Leibowitz Pharmacist Naturopath
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Agenda• Types of Arthritis• Traditional Western Medications• Plant-based Herbals• Glucosamine/ Chondroitin• GLA• Products show and tell• Questions
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Treatment Modalities Arthritis• NSAIDS• Analgesics• DMARDS (Disease-modifying anti-rheumatic drugs, for
RA)• Corticosteroids• TNF inhibitors• Intra-articular hylands and synovial fluid substitutes
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White Willow Bark• It works like aspirin• Anti-inflammatory• Can “thin” the blood, prevent clots• Side effects: Nausea, stomach pain, tinnitis, kidney and
liver toxicity, Reye’s syndrome
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White Willow Bark• Salix alba• Underside of leaves are white and hairy• Main ingredients in salicin• Isolated by French pharmacist in 1828• Salicin can convert to salicylic acid
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Nettle Leaves
• Yellow rhizomes and stolons• Stinging and non-sting hairs• Containing vitamin A, folate, calcium, proteins, iron • Flavor similar to spinach• Used in Germany for BPH and arthritis
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Nettle Leaves• Anti-inflammatory components • Block production of prostaglandins • Active compounds reduce TNF-alpha and IL-1B• Inhibits at the genetic level to reduce compounds in
synovial fluid• Comparable to Enbrel• Bodybuilders use it to increase free testosterone
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Boswellia Serrata • Known as Indian Frankincese• Used in Ayurveda• Boswellic acids contain anti- inflammatory compounds• Boswellic active compound called AKBA• Inhibits 5-lipoxygenase
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Boswellia Serrata • Research team including MD from Arthritis Foundation
have done studies • Double-blind, placebo-controlled study for OA • Pain and physical ability before study and 7, 30, 60, 90
days after• 250mg Boswellia reduced pain, increased joint function,
reduced levels of cartilage-degrading enzyme MMP-3• Side effects: Stomach upset, skin rashes
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Bromelain• Anti-inflammatory found in pineapples• Studies in Germany show improvement with knee
osteoarthritis, decreased swelling after torn ligaments • German Commission E dose is 80-320mg two-three times
daily• Arthritis dose is 500-2000mg daily• Destroyed by heat
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Bromelain• 1-8 pineapples/day!• Bromelain can increase glucosamine absorption by up to
90%• Many drug interactions!• Caution: Antibiotics, Sedatives, Blood thinners
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Glucosamine/Chondroitin/MSM• Many manufacturers• 1500mg glucosamine/ 1200mg chondroitin• Does not work for everyone• MSM useful at higher elevations only (High altitude
climbers) where lack of oxygen
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Gamma Linolenic Acid (GLA)• Found in seeds and oils of plants • Essential fatty acids • Most concentrated one is Borage oil• Others include evening primrose, blackcurrant seed oil• Benefits seen after 6 months and doses of 1.4g/day of
GLA
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Omega-3 Fatty Acids• Body can’t make itself, so get from diet • Food sources are salmon, tuna, trout, nuts seeds, cooking
oils• Form leukotrienes which stop inflammation• Most useful in rheumatoid arthritis
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Tips to Get Omaga-3 in Diet • Eat salmon and tuna• Use canola oil instead of corn oil• Corn oil contains Omega-6 which promotes inflammation
vs canola oil which has Omega-3• Omega-3 Supplements in capsules
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Examples of GLA sources Borage Seeds Evening Primrose
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Spices, Foods and Arthritis • Tumeric and garlic both antioxidants and anti-
inflammatories • Studies in 1980 India 1200mg curcumin decrased joint
swelling and stiffness comparable to rx phenylbutazone, but study flawed no placebo group
• Green tea-antioxidant polphenols neutralize free radicals • Cayenne• Chili Pepper ( Capsicum) topical
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Herbs, Teas Poultices, Creams • Need correct concentrations to be effective (ie/
glucosamine)• Creams such as capsaicin have limited use • Teas minimal effect • Medications may interfere with absorption
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THANK YOU!Questions
And Show and tell