NATIONAL ORTHOPAEDIC REGISTRY MALAYSIA … fileDr Nahulan A/L Theva Rajah Head of Department, ......
Transcript of NATIONAL ORTHOPAEDIC REGISTRY MALAYSIA … fileDr Nahulan A/L Theva Rajah Head of Department, ......
NATIONAL ORTHOPAEDIC REGISTRY MALAYSIA (NORM)
ANNUAL REPORT OF
NATIONAL ORTHOPAEDIC REGISTRY MALAYSIA (NORM) DIABETIC FOOT
2009
Editors:
Dr Mohammad Anwar Hau Abdullah Dr Ahmad Tajuddin Abdullah
Registry Committee
Dr Mohammad Anwar Hau Abdullah
Dr Ahmad Tajuddin Abdullah
Dr Zulkiflee Osman
Dr Saadon Ibrahim
Dr Mohamad Yazid Din
Dr Joehaimey Johari
Dr Se To Boon Chong
Dr Tan Boon Cheong
Dr Abdul Rauf Ahmad
Dr Mohd Zamzuri Mohd Zain
Dr Pan Chee Huan
A publication of the National Orthopaedic Registry of Malaysia (NORM) and the
Clinical Research Centre, Ministry of Health Malaysia
*********************************************************************
December 2010
© National Orthopaedic Registry of Malaysia (NORM)
Publisher:
Jointly published by the National Orthopedic Registry of Malaysia (NORM) and the
Clinical Research Centre (CRC), Ministry of Health Malaysia.
National Orthopaedic Registry of Malaysia
1st Floor MMA House,
124, Jalan Pahang,
53000 Kuala Lumpur,
Malaysia.
Tel : (603) 4044 3060 / (603) 4044 3070 Fax : (603) 4044 3080 Email : [email protected]
Website : http://www.acrm.org.my/norm
Suggested citation: Mohammad Anwar Hau Abdullah, Ahmad Tajuddin Abdullah (Eds). Annual Report of the NORM- Registry, 2009. Kuala Lumpur, Malaysia: National Orthopaedic Registry of Malaysia 2009.
Disclaimer:
Data reported in this report were collected for one year period (from January to
December 2009), this report is copyrighted. Reproduction and dissemination of this
report in part or in whole for research, educational or other non-commercial purposes
are authorized without any prior written permission from the copyright holders
provided the source is fully acknowledged.
Electronic version
The electronic version of this report may be downloaded at
http://www.acrm.org.my/norm or http://www.crc.gov.my/publication/report.
Funding
The National Orthopaedic Registry of Malaysia (NORM) – Diabetic Foot Registry is
funded with grants from the Ministry of Health Malaysia (MOH).
ACKNOWLEDGEMENTS
The National Orthopaedic Registry of Malaysia (NORM) would like to give its grateful
appreciation to everyone who has helped make this report possible.
We would especially like to thank the following:
Clinical Research Centre Dr Goh Pik Pin
Clinical Epidemiology Unit Dr Jamaiyah Haniff
Dr Dr Sharmini Selvarajah Dr Lim Chioa mei
Patient Registry Unit Dr Jaya Purany Stanley Ponniah Nurul Shuhada Binti Mohd Ali
Scottish Hip Fracture Registry
NORM Governance Board
Chairman Dato’ Dr Azmi Shafei
Director,
Division of Medical Development,
Ministry of Health Malaysia.
Members Dr Jamaiyah Haniff
Head Of Clinical Epidemiology Unit,
Clinical Research Center, Hospital Kuala Lumpur.
Dr Jaya Purany Stanley Ponniah
Head of Patient Registry Unit
Clinical Research Center, Hospital Kuala Lumpur.
Dr Mohammad Anwar Hau Abdullah
Head of Department,
Department of Orthopaedic and Traumatology,
Hospital Raja Perempuan Zainab II, Kota Bharu.
Dr Ahmad Tajuddin Abdullah
Head of Department,
Department of Orthopaedic and Traumatology,
Hospital Sultanah Nur Zahirah, Kuala Terengganu.
Dr Saadon Ibrahim
Department of Orthopaedic and Traumatology,
Hospital Sultan Ismail, Johor Bharu.
Dr Se To Boon Chong
Department of Orthopaedic and Traumatology,
Hospital Pulau Pinang,Pulau Pinang.
Dato’ Dr Suresh Chopra,
Head of Department,
Department of Orthopaedic and Traumatology,
Hospital Sultanah Bahiyah, Alor Setar.
Dr Abdul Rauf Ahmad
Head of Department,
Department of Orthopaedic and Traumatology,
Hospital Tuanku Jaafar, Seremban.
Dato’ Dr Premchandran Menon
Head of Department,
Department of Orthopaedic and Traumatology,
Hospital Tengku Ampuan Afzan (HTAA), Kuantan.
Dr Pan Chee Huan
Head of Department,
Department of Orthopaedic and Traumatology,
Hospital Tuanku Fauziah, Kangar.
Dr Thirumal a/l Manickam
Head of Department,
Department of Orthopaedic and Traumatology,
Hospital Tengku Ampuan Rahimah, Klang.
Dr Nahulan A/L Theva Rajah
Head of Department,
Department of Orthopaedic and Traumatology,
Hospital Queen Elizabeth, Kota Kinabalu.
Dato’ Dr Ramanathan A/L Ramiah
Head of Department,
Department of Orthopaedic and Traumatology,
Hospital Raja Permaisuri Bainun, Ipoh.
Mr.Sivapathasundaram A/L Nadarajah
Head of Department,
Department of Orthopaedic and Traumatology
Hospital Melaka, Melaka.
Dr K. Thevarajan
Head of Department,
Department of Orthopaedic and Traumatology,
Hospital Sultanah Aminah, Johor Bharu.
Dr Faris Kamaruddin
Head of Department,
Department of Orthopaedic and Traumatology,
Hospital Umum Sarawak, Sarawak.
NORM Steering Committee members:
Chairman Dr Ahmad Tajuddin Abdullah
Head of Department,
Department of Orthopaedic and Traumatology,
Hospital Sultanah Nur Zahirah, Kuala Terengganu.
Co-Chairman Dr Zulkiflee Osman
Head of Department,
Department of Orthopaedic and Traumatology,
Hospital Kuala Lumpur.
Members Dr Mohammad Anwar Hau Abdullah
Head of Department,
Department of Orthopaedic and Traumatology,
Hospital Raja Perempuan Zainab II, Kota Bharu.
Dr Saadon Ibrahim
Department of Orthopaedic and Traumatology,
Hospital Sultan Ismail, Johor Bharu.
Dr Se To Boon Chong
Department of Orthopaedic and Traumatology,
Hospital Pulau Pinang, Pulau Pinang.
Dr Tan Boon Cheong
Department of Orthopaedic and Traumatology,
Hospital Pulau Pinang, Pulau Pinang.
Dr Abdul Rauf Ahmad
Department of Orthopaedic and Traumatology,
Hospital Tuanku Jaafar, Seremban.
Dr Mohd Zamzuri Mohd Zain
Department of Orthopaedic and Traumatology,
Hospital Tengku Ampuan Afzan (HTAA), Kuantan.
Dr Pan Chee Huan
Department of Orthopaedic and Traumatology,
Hospital Tuanku Fauziah, Kangar.
Dr Mohamad Yazid Din
Department of Orthopaedic and Traumatology,
Hospital Sultanah Bahiyah, Alor Setar.
Dr Joehaimey Johari
Department of Orthopaedic and Traumatology,
Hospital Raja Perempuan Zainab II, Kota Bharu.
NORM SOURCE DATA PROVIDERS 2008/2009
The current source data providers for NORM are:
No. Hospital Site investigators Second person-in-charge
1 Hospital Kuala
Lumpur
Mr Zulkiflee Osman Dr Mahazura Hj Mat Lawi
Dr. Abdul Qahhar
2 Hospital Raja
Perempuan
Zainab II Kota
Bharu
Mr Mohammad Anwar Hau
Abdullah
Dr Joehaimey Johari
Sister Nik Noriah Nik Ibrahim
3 Hospital Sultanah
Nur Zahirah Kuala
Terengganu
Mr Ahmad Tajuddin Abdullah
Dr Mustaqim Afifi @ Apipi
Dr Hazulin Mohd Radzuan
Dr Muhammad Hilmi Nasir
Dr Mohd Ariff Razani Abd
Razak
4 Hospital Tengku
Ampuan Rahimah
Klang
Dr Gurjit Singh Dr M. Thirumal
5 Hospital Sultanah
Bahiyah Alor Setar
Dr Mohamad Yazid Din
Dr Noor Mahazrinna
Hayadin
Dr Lim Chiao Yee
6 Hospital Sultanah
Aminah Johor
Bahru
Dr Yoga Raj A/L
Parameswaran
Dr Manamohan
Chandrarajan
Dr Mohd Adham Shah
Dr Teo Pock Chin
7 Hospital Melaka
Dr Rengsen Parthiban Dr Azhar Asari
Dr Mohd. Karim Md Isa
MA Mohd Fharid Johan
SN Marina Mohamed @
Osman
8 Hospital Sultan
Ismail Johor Bahru
Dr Saadon Ibrahim Dr Mursyida Md Nujid
Dr Jayamalar
Thurairajasingam
SN Rohayah Abdul Rahman
JM Yussilawani Mamat
9 Hospital Tuanku
Fauziah Kangar
Dr Pan Chee Huan
Mr Yeap Ewe Juan
Mr Zakaria Yusoff
Dr Badrul Hashim
Dr Zakaria Yusoff
MA Shahizam Shafiee
SN Norseha Baharom
10 Hospital Raja
Permaisuri Bainun
Ipoh
Dr Manoharan Dr Selvynlloyd
Dr Iyngkaran Arasalingam
11 Hospital Tengku
Ampuan Afzan
Kuantan
Dato' Dr N Premchandran
Dr. Mohd Zamzuri Mohd
Zain
Dr Alaudin Haris Osman
Dr Jeffrey Jaya Raj
Dr Ahmad Hafiz bin Zulkifly
12 Hospital Ampang Dr Ng Yue Oon Dr Lynn Azura Md Sham
Dr Samyu Ali
13 Hospital Tuanku
Ja’afar Seremban
Dr Abdul Rauf Ahmad Dr Ng Tiong Soon
Dr Johann Johari
Sr Khamisah A. Ghani
Sr Rohana Zakaria
14 Hospital Pulau
Pinang
Dr Se To Boon Chong Dr Tan Boon Cheong
Dr Ooi Chee Lean
Dr Chan Kok Yu
15 Hospital Serdang Dr Khoo Shaw Woei Dr Imma Isniza
Dr Harminder Singh
Randhawa
16 Hospital Selayang Dr Ng Swee Soon Dr Ritzwan Ismayatim
Dr Amir Fariz Zakaria
17 Hospital Queen
Elizabeth Kota
Kinabalu
Dr Nahulan A/L Theva Rajah Dr CS Kumar
18 Hospital Umum
Sarawak
Dr Faris Kamaruddin Dr Aaron Gerard Paul
MA Mikim A/K Radem
9
PREFACE
The National Orthopaedic Registry Malaysia has been collecting data since mid 2008
and it is with great pleasure and pride that we see this report materialised.
I would like to thank all those who have collected, verified and analysed the data.
The co-operation and energy demonstrated in units throughout the country indicates
the importance they place on improving patient management
The success of this report is due to continuous support and cooperation from various
people and agencies. The effort of the entire group must be congratulated and it has
been my sincere hope that this registry is able to sustain in coming years.
I also take this opportunity to thank the Clinical Research Centre Ministry of Health
Malaysia, to have trust in us and to provide us with the funding for us embark in this
project. This annual report is a testament of all your combined effort.
Thank you,
Dr Ahmad Tajuddin bin Abdullah
Dr Mohammad Anwar Hau Abdullah
Chairman National Orthopaedic Registry of Malaysia
Ministry of Health Malaysia
10
ABBREVIATIONS
ASA American Society of Anaesthesiologists
CRC Clinical Research Centre
CRF Case Report Form
csv Comma separated value
Dr Doctor
GA General Anaesthesia
HTAA Hospital Tengku Ampuan Afzan
ICT Information and Communication Technology
LMWH Low Molecular Weight Heparin
MJM Medical Journal of Malaysia
MOH Ministry of Health
NOHFR National Orthopaedic Hip Fracture Registry
NORM National Orthopaedic Registry of Malaysia
OT Operation Theater
PTH Parathyroid Hormone
RTA Road Traffic Accident
SDP Source Data Provider
SERMS Selective Estrogen Receptor Modulators
SMS Short Messaging System
txt Text-delimited format
xls Excel workbook
11
Table of Content
Table Page
SECTION 1: PATIENT DETAILS AND DEMOGRAPHIC ..................................................................... 13 Table 1.1: Profile demographic of respondents, Diabetes Foots and Hands, National Orthopadic Registry Malaysia (NORM) 2009. (N=1254) ................................................................... 13 Table 1.2: Occupation of respondents, Diabetes Foots and Hands, National Orthopadic Registry Malaysia (NORM) 2009. (N=1254) ...................................................................................... 14
SECTION 2: ADMISSION .............................................................................................................. 15 Table 2.1: Status of admision, Diabetes Foots and Hands, National Orthopadic Registry Malaysia (NORM) 2009. .................................................................................................................... 15
SECTION 3: DIABETES HISTORY ................................................................................................... 16 Table 3.1: Status of diabetes mellitus, Diabetes Foots and Hands, National Orthopadic Registry Malaysia (NORM) 2009. ...................................................................................................... 16
SECTION 4: TREATMENT OF DIABETES MELLITUS ......................................................................... 17 Table 4.1: Treatment of diabetes mellitus, Diabetes Foots and Hands, National Orthopadic Registry Malaysia (NORM) 2009. ...................................................................................................... 17 Table 4.2: Status of compliance for treatment, Diabetes Foots and Hands, National Orthopadic Registry Malaysia (NORM) 2009. ................................................................................... 18
SECTION 5: TREATMENT OF CURRENT DIABETES FOOT/ HANDS ULCER ........................................ 18 Table 5.1: Treatment of current diabetes foot/ hands ulcer, Diabetes Foots and Hands, National Orthopadic Registry Malaysia (NORM) 2009 ..................................................................... 18
SECTION 6: RISK FACTORS .......................................................................................................... 19 Table 6.1: Distribution of infection, Diabetes Foots and Hands, National Orthopadic Registry Malaysia (NORM) 2009 ....................................................................................................... 19 Table 6.2: Risk factors for upper limb (n = 60), Diabetes Foots and Hands, National Orthopadic Registry Malaysia (NORM) 2009 .................................................................................... 19 Table 6.3: Risk factors of lower limb (n = 1198), Diabetes Foots and Hands, National Orthopadic Registry Malaysia (NORM) 2009 .................................................................................... 20 Table 6.4: Risk factors (awareness), Diabetes Foots and Hands, National Orthopadic Registry Malaysia (NORM) 2009 ....................................................................................................... 20 Table 6.5: Practice for past one year, Diabetes Foots and Hands, National Orthopadic Registry Malaysia (NORM) 2009 ....................................................................................................... 21 Table 6.6: Risk factors (co-morbidity, complications, family history), Diabetes Foots and Hands, National Orthopadic Registry Malaysia (NORM) 2009 ......................................................... 22
SECTION 7: PREVIOUS HANDS/FOOT PROBLEMS (PAST ONE YEAR) .............................................. 23 Table 7.1: Previous hands/foot problems (past one year), Diabetes Foots and Hands, National Orthopadic Registry Malaysia (NORM) 2009 ..................................................................... 23 Table 7.2: Highest level of amputation, previous hands/foot problems (past one year), Diabetes Foots and Hands, National Orthopadic Registry Malaysia (NORM) 2009 ......................... 24
SECTION 8: CURRENT UPPER LIMBS INFECTIONS ......................................................................... 25 Table 8.1: Dominance of current upper limbs infections (n=60), Diabetes Foots and Hands, National Orthopadic Registry Malaysia (NORM) 2009 ..................................................................... 25 Table 8.2: Infection and location of current upper limbs infections (n=60), Diabetes Foots and Hands, National Orthopadic Registry Malaysia (NORM) 2009 .................................................. 25 Table 8.3: Diagnosis of current upper limbs infections (n=60), Diabetes Foots and Hands, National Orthopadic Registry Malaysia (NORM) 2009 ..................................................................... 26 Table 8.4: Classification of current upper limbs infections (n=60), Diabetes Foots and Hands, National Orthopadic Registry Malaysia (NORM) 2009 ......................................................... 26
12
Table 8.5: Associated complications of current upper limbs infections (n=60), Diabetes Foots and Hands, National Orthopaedic Registry Malaysia (NORM) 2009 ...................................... 27 Table 8.6: Precipitating factor of current upper limbs infections (n=60), Diabetes Foots and Hands, National Orthopaedic Registry Malaysia (NORM) 2009 ................................................ 27 Detail for precipitating factor in appendix 3 ..................................................................................... 27 Table 8.7: Physical findings of current upper limbs infections (n=60), Diabetes Foots and Hands, National Orthopaedic Registry Malaysia (NORM) 2009 ....................................................... 28 Table 8.8: Current upper limbs infections (culture), Diabetes Foots and Hands, National Orthopadic Registry Malaysia (NORM) 2009 .................................................................................... 28 Table 8.9: Current upper limbs infections (operations during admision), Diabetes Foots and Hands, National Orthopadic Registry Malaysia (NORM) 2009 .................................................. 29 Table 8.10: Current upper limbs infections (culture, operations during admission and clinical outcome), Diabetes Foots and Hands, National Orthopadic Registry Malaysia (NORM) 2009 .................................................................................................................................... 30
SECTION 9: CURRENT LOWER LIMBS INFECTIONS ........................................................................ 30 Table 9.1: Current lower limbs infections (infections and location), Diabetes Foots and Hands, National Orthopadic Registry Malaysia (NORM) 2009 ......................................................... 30 Table 9.2: Current lower limbs infections (diagnosis and classification), Diabetes Foots and Hands, National Orthopadic Registry Malaysia (NORM) 2009 ......................................................... 31 Table 9.3: Current lower limbs infections (associated complications, precipitating factor and physical findings), Diabetes Foots and Hands, National Orthopaedic Registry Malaysia (NORM) 2009 .................................................................................................................................... 32 Table 9.4: Current lower limbs infections (culture), Diabetes Foots and Hands, National Orthopadic Registry Malaysia (NORM) 2009 .................................................................................... 33 Table 9.5: Current lower limbs infections (operations during admision), Diabetes Foots and Hands, National Orthopadic Registry Malaysia (NORM) 2009 .................................................. 34 Table 9.6: Current lower limbs infections (culture, operations during admission and clinical outcome), Diabetes Foots and Hands, National Orthopadic Registry Malaysia (NORM) 2009 .................................................................................................................................... 35
SECTION 10: ANTIBIOTICS ........................................................................................................... 36 Table 10.1: Antibiotics, Diabetes Foots and Hands, National Orthopadic Registry Malaysia (NORM) 2009 .................................................................................................................................... 36
13
Section 1: Patient Details and Demographic
Table 1.1: Profile demographic of respondents, Diabetes Foots and Hands,
National Orthopadic Registry Malaysia (NORM) 2009. (N=1254)
Profile Statistics n %
Age
Mean (SD) 56.2 (11.6)
Median IQR (1stQ, 3rdQ)
Min, max 20, 94
Age group
18 – 29 21 1.7
30 – 39 60 4.8
40 - 49 255 20.3
50 - 59 438 34.9
≥ 60 480 38.3
Gender
Male 604 48.2
Female 650 51.8
Ethnicity (na=5)
Malay 935 74.6
Chinese 141 11.2
Indian 146 11.6
Others Malaysian 17 1.4
Non Malaysian 10 0.8
Residence (na=113)
Urban 610 53.5
Rural 351 46.5
Education level (na=467)
Primary 388 49.3
Secondary 355 45.1
Tertiary 44 5.6
14
Table 1.2: Occupation of respondents, Diabetes Foots and Hands, National
Orthopadic Registry Malaysia (NORM) 2009. (N=1254)
Profile n %
Occupation
Legislator senior 3 0.2
Technicians 3 0.2
Service 42 3.5
Related trade 4 0.3
Elementary occupation 7 0.6
Profesional 10 0.8
Clerical 17 1.4
Agricultural 21 1.7
Machine operator 20 1.7
Housewife 431 35.8
Unemployed 133 11.0
Retired 166 13.8
Unknown 185 15.4
Others 163 13.5
15
Section 2: Admission
Table 2.1: Status of admision, Diabetes Foots and Hands, National Orthopadic
Registry Malaysia (NORM) 2009.
Status of admision Statistics n %
Duration in days
Mean (SD) 13.7 (68.5)
Median IQR (1stQ, 3rdQ) 7.0 IQR (4.0, 14.0)
Min, max 0, 2228
Duration in days by age group Median IQR (1stQ, 3rdQ)
18 – 29 8.5 IQR (6.0, 17.5)
30 – 39 5.0 IQR (3.5, 10.5)
40 - 49 8.0 IQR (4.0, 15.0)
50 - 59 6.0 IQR (4.0, 12.0)
≥ 60 7.0 IQR (4.0, 14.5)
Previous admission (na=142)
Yes 425 38.2
No 687 61.8
Number of times (na=908)
1 time only 192 55.5
2 – 3 134 38.7
4 – 5 11 3.2
> 5 9 2.6
16
Section 3: Diabetes History
Table 3.1: Status of diabetes mellitus, Diabetes Foots and Hands, National
Orthopadic Registry Malaysia (NORM) 2009.
Status of diabetes Statistics n %
Type of diabetes
Type 1 197 16.2
By age group:
18 – 29 10 5.1
30 – 39 16 8.1
40 - 49 35 17.8
50 - 59 70 35.5
≥ 60 66 33.5
Type 2 1021 83.8
By age group:
18 – 29 9 0.9
30 – 39 43 4.2
40 - 49 211 20.7
50 - 59 356 35.0
≥ 60 398 39.1
Duration of diabetes in years:
Type 1
Mean (SD) 11.9 (7.7)
Median IQR (1stQ, 3rdQ) 10.0 IQR (5.0, 16.0)
Min, max 1.0, 40.0
Type 2
Mean (SD) 10.4 (7.5)
Median IQR (1stQ, 3rdQ) 10.0 IQR (5.0, 15.0)
Min, max 1.0, 40.0
17
Section 4: Treatment of Diabetes Mellitus
Table 4.1: Treatment of diabetes mellitus, Diabetes Foots and Hands, National
Orthopadic Registry Malaysia (NORM) 2009.
Treatment of Diabetes Mellitus Descriptive summary*
n %
Patient on treatment (na = 97 and missing = 2)
Yes 1071 92.7
No 84 7.27
Treatment for diet (na = 723 and missing = 176)
Yes 131 36.9
No 224 63.1
Duration for having diet treatment (days)* (n = 122)
Mean (SD) 75.9 (74.6)
Median IQR (1stQ, 3rdQ) 60 IQR (12, 120)
Min, max 1, 300
Other treatment (na = 111 and missing = 174)
Insulin 165 17.0
OHA 692 71.5
OHA and insulin 111 11.5
None of the above 1 -
Duration of having other treatment*
Insulin (n = 98)
Mean (SD) 45.5 (62.5)
Median (IQR) 20.5 IQR (7, 60)
Min, max 1, 360
OHA (n = 287)
Mean (SD) 75.1 (87.0)
Median IQR (1stQ, 3rdQ) 36 IQR (12, 120)
Min, max 1, 480
OHA and insulin (n = 71)
Mean (SD) 75.8 (84.2)
Median IQR (1stQ, 3rdQ) 48 IQR (10, 120)
Min, max 1, 362
18
Table 4.2: Status of compliance for treatment, Diabetes Foots and Hands, National
Orthopadic Registry Malaysia (NORM) 2009.
Treatment of Diabetes Mellitus
Status of compliance (na = 197 and missing = 181)
Yes n (%)
No n (%)
18 – 29 8 (61.5) 1.3 (38.5)
30 – 39 27 (64.3) 4.2 (35.7)
40 – 49 136 (74.7) 21.2 (25.3)
50 – 59 229 (75.3) 35.7 (24.7)
≥ 60 241 (72.4) 37.6 (27.6)
Section 5: Treatment of Current Diabetes Foot/ Hands Ulcer
Table 5.1: Treatment of current diabetes foot/ hands ulcer, Diabetes Foots and
Hands, National Orthopadic Registry Malaysia (NORM) 2009
Treatment of current DFH Descriptive summary*
n %
Management of the ulcer prior to hospitalization
Nil 312 -
Self treatment 78 7.7
General practitioner 114 11.3
Private hospital 36 3.6
Traditional 34 3.4
Government hospital 510 50.6
Government clinic 233 23.1
Alternative treatment 3 0.3
Duration of treatment (days) (n = 327)
Mean (SD) 568.2 (1615.0)
Median IQR (1stQ, 3rdQ) 14 IQR (5, 60)
Min, max 1, 10950 *10950 is similar to 30.4 years
19
Section 6: Risk Factors
Table 6.1: Distribution of infection, Diabetes Foots and Hands, National Orthopadic
Registry Malaysia (NORM) 2009
Infection Single Both Total
n row% n row% n col%
Upper limb infection (na = 86 and no = 1108))
60 100.0 0 0.0 60 100.0
By age group
18 – 29 4 100.0 0 0.0 4 6.8
30 – 39 9 100.0 0 0.0 9 15.3
40 - 49 17 100.0 0 0.0 17 28.8
50 – 59 12 100.0 0 0.0 12 20.3
≥ 60 17 100.0 0 0.0 17 28.8
Lower limb infection (na= 5 and no = 51)
1151 96.1 47 3.9 1198 100.0
By age group
18 – 29 17 100.0 0 0.0 17 1.4
30 – 39 50 98.0 1 2.0 51 4.3
40 - 49 230 96.2 9 3.8 239 20.0
50 – 59 414 96.7 14 3.3 428 35.8
≥ 60 439 95.0 23 5.0 462 38.6
Table 6.2: Risk factors for upper limb (n = 60), Diabetes Foots and Hands, National
Orthopadic Registry Malaysia (NORM) 2009
Risk factors n %
Activities at work:
Use hand predominantly 46 76.7
Hand wet at work 22 36.7
20
Table 6.3: Risk factors of lower limb (n = 1198), Diabetes Foots and Hands, National
Orthopadic Registry Malaysia (NORM) 2009
Risk factors n %
Activities at work:
Involve lots of walking/standing
568 47.4
Feet wet at work 228 19.0
Footware at work: (na = 221 and missing = 10)
Barefoot 99 10.2
Slippers 457 47.3
Shoes 408 42.2
Socks only 3 0.3
Footware at home: (na = 126 and missing = 10)
Barefoot 526 49.5
Slippers 487 45.9
Shoes 36 3.4
Socks only 13 1.2
Table 6.4: Risk factors (awareness), Diabetes Foots and Hands, National
Orthopadic Registry Malaysia (NORM) 2009
Risk factors n %
Foot/hands problem (N = 1254)
Aware of increased foot/hand problem 779 62.1
Aware: Inspect feet/hand 627 50.0
Foot problem (n = 1198)
Aware:Wash feet 830 69.3
Aware: Apply emollients 278 23.2
Aware: Use appropriate shoes 318 26.5
Aware: Attend diabetes foot clinic 211 17.6
Aware: Education on diabetes footcare (formal) 327 27.3
Aware: Education on diabetes footcare (informal) 595 49.7
Aware: Keeping on diabetes care booklet 273 22.8
21
Table 6.5: Practice for past one year, Diabetes Foots and Hands, National
Orthopadic Registry Malaysia (NORM) 2009
Practice for past one year: n %
Inspect feet/hand (N = 1254) 563 44.9
Frequent Inspect feet/hand
Daily 206 37.3
Weekly 63 11.4
Occationally 284 51.4
Total 553
Wash feet (n = 1198) 733 64.5
Frequent wash feet
Daily 501 69.8
Weekly 36 5.0
Occationally 181 25.2
Total 718
Apply emollients (n = 1198) 299 19.1
Frequent apply emollients
Daily 132 45.4
Weekly 20 6.9
Occationally 139 47.8
Total 291
Use appropriate shoes (n = 1198) 286 23.9
Frequent use appropriate shoes
Daily 134 48.9
Weekly 17 6.2
Occationally 123 44.9
Total 274
Attend diabetes foot clinic (n = 1198) 190 15.9
Frequent attend diabetes foot clinic
Daily 58 28.3
Weekly 122 59.5
Occationally 0 0.0
Total 180
22
Table 6.6: Risk factors (co-morbidity, complications, family history), Diabetes Foots
and Hands, National Orthopadic Registry Malaysia (NORM) 2009
Risk factors n %
Co-morbidity:
Unknown 468
Hypertension 685 61.2
Hypercholesterolemia 133 11.9
IHD 102 9.1
TIA 1 0.1
CVA 39 3.5
Renal disease 51 4.6
Retinopathy 54 4.8
Others 55 4.9
Complications:
Nil 216
Unknown 253
Retinopathy 205 17.2
Vascular 194 16.3
Neuropathy 420 35.2
Skin 261 21.9
Nephropathy 101 8.5
Others 12 1.0
Family history:
Unknown 636
Hypertension 291 29.9
DM 538 55.3
Hypercholesterolemia 38 3.9
IHD 65 6.7
TIA 1 0.1
CVA 18 1.8
Renal disease 3 0.3
Retinopathy 7 0.7
Others 12 1.2 Co-morbidity details refer to appendix 1 Complications details refer to appendix 2 Family history details refer to appendix 2
23
Section 7: Previous Hands/foot problems (past one year)
Table 7.1: Previous hands/foot problems (past one year), Diabetes Foots and
Hands, National Orthopadic Registry Malaysia (NORM) 2009
Previous problems n %
Previous operations performed (N = 1254)
373 29.7
1 time 235 65.1
2 – 4 times 116 32.1
5 – 7 times 8 2.2
8 – 10 times 2 0.6
Total 361
24
Table 7.2: Highest level of amputation, previous hands/foot problems (past one
year), Diabetes Foots and Hands, National Orthopadic Registry Malaysia (NORM)
2009
Highest level of amputation n
None 289
Upper limbs (single) 2
Finger’s 0
Ray 2
Below wrist 0
Below elbow 0
Above elbow 0
Forequarter 0
Upper limbs (both) 0
Finger’s 0
Ray 0
Below wrist 0
Below elbow 0
Above elbow 0
Forequarter 0
Lower limbs (single) 44
Disarticulation 9
Ray 24
Transmetatarsal 0
Syme’s 0
Below knee 6
Through knee 0
Above knee 5
Hip disarticulation 0
Left lower limbs (both) 3
Disarticulation 0
Ray 2
Transmetatarsal 0
Syme’s 0
Below knee 1
Through knee 0
Above knee 0
Hip disarticulation 0
25
Section 8: Current Upper Limbs Infections
Table 8.1: Dominance of current upper limbs infections (n=60), Diabetes Foots and
Hands, National Orthopadic Registry Malaysia (NORM) 2009
Right Left Total
n % n % n %
Dominance (na=3) 50 87.7 7 12.3 57 100.0
Table 8.2: Infection and location of current upper limbs infections (n=60), Diabetes
Foots and Hands, National Orthopadic Registry Malaysia (NORM) 2009
Total
n %*
Infections 60 100.0
Digit
1 7 11.7
2 7 11.7
3 11 18.3
4 3 5.0
5 3 5.0
0.0
Arm 4 6.7
Forearm 5 8.3
Hand: Pulmer surface 17 28.3
Hand: Dorsum 11 18.3
Web space 0.0
1st 1 1.7
2nd 4 6.7
3rd 4 6.7
4th 4 6.7
Amputation stump 0.0
Below wrist 1 1.7
Below elbow 3 5.0
Above elbow 0 0.0 % derived using denominator 60 (number of upper limb infection)
26
Table 8.3: Diagnosis of current upper limbs infections (n=60), Diabetes Foots and
Hands, National Orthopadic Registry Malaysia (NORM) 2009
Total
n %*
Diagnosis
Cellulitis 16 26.7
Felon 2 3.3
Thenar abscess 5 8.3
Mid palmar abscess 4 6.7
Hypothenar 2 3.3
Collar button abscess 1 1.7
Flexor tenosynovitis 5 8.3
Radial bursae/thumb 3 5.0
Paronychia 2 3.3
Septic arthritis 1 1.7
Dry gangrene 4 6.7
Wet gangrene 4 6.7
Necrotising fascilitis 1 1.7
Ulcer 2 3.3
Osteomyelitis 0 0.0
Others 13 21.7
Total 65 Diagnosis details refer to appendix 2 % derived using denominator 60 (number of upper limb infection)
Table 8.4: Classification of current upper limbs infections (n=60), Diabetes Foots
and Hands, National Orthopadic Registry Malaysia (NORM) 2009
Total
n %*
Stage
A 7 11.7
B 9 15.0
C 1 1.7
D 2 3.3
Grade 0.0
0 4 6.7
1 9 15.0
2 4 6.7
3 2 3.3 % derived using denominator 60 (number of upper limb infection)
27
Table 8.5: Associated complications of current upper limbs infections (n=60),
Diabetes Foots and Hands, National Orthopaedic Registry Malaysia (NORM) 2009
Total
n %*
Nil 56 93.3*
Associated complications
Septicaemia 3 5.0
Pneumonia 0 0.0
Stroke 0 0.0
UGIB 0 0.0
Renal failure 0 0.0
CCF 1 1.7
Pressure sores 0 0.0 % derived using denominator 60 (number of upper limb infection)
Table 8.6: Precipitating factor of current upper limbs infections (n=60), Diabetes
Foots and Hands, National Orthopaedic Registry Malaysia (NORM) 2009
Total
n %*
Precipitating factor
Spontaneous 25 41.7
Minor trauma 22 36.7
Major trauma 1 1.7
Insect bite 0 0.0
Animal bite 3 5.0
Work related 0 0.0
Recreational related 0 0.0
Latrogenic 1 1.7
Others 3 5.0
Unknown 5 8.3 Detail for precipitating factor in appendix 3 % derived using denominator 60 (number of upper limb infection)
28
Table 8.7: Physical findings of current upper limbs infections (n=60), Diabetes
Foots and Hands, National Orthopaedic Registry Malaysia (NORM) 2009
Physical findings Total
n %*
Palpable brach. artery 47 78.3
Palpable radial artery 47 78.3
Peripheral neuropathy 16 26.7 % derived using denominator 60 (number of upper limb infection)
Table 8.8: Current upper limbs infections (culture), Diabetes Foots and Hands,
National Orthopadic Registry Malaysia (NORM) 2009
Infections Total
n %*
Culture:
1st culture
No growth 18 30.0
Mixed growth 7 11.7
Single growth 23 38.3
Mixed growth
Acinetobacter 1 1.7
Anaerobic 0 0.0
Bacteroides 0 0.0
Coagulase 1 1.7
Enterococcus 0 0.0
Enterobacter 3 5.0
Escherichia 0 0.0
Klebsiella 7 11.7
Proteus 0 0.0
Serratia 0 0.0
Pseud. aeruginosa 1 1.7
Pseud. spp 0 0.0
Staphylococcus 15 25.0
B-hemolytic strep. 3 5.0
Viridans strep. 0 0.0
Others 3 5.0 Mixed growth details refer to appendix 3 % derived using denominator 60 (number of upper limb infection)
29
Table 8.9: Current upper limbs infections (operations during admision), Diabetes
Foots and Hands, National Orthopadic Registry Malaysia (NORM) 2009
Infections Total
n %*
Operation during admission
Nil 11 18.3
Amputation 19 31.7
Wound debridement 40 66.7
Amputation 0.0
Fingers 14 23.3
Ray 3 5.0
Below wrist 0 0.0
Below elbow 1 1.7
Above elbow 1 1.7
Forequarter 0 0.0
Finger’s 0.0
1 2 3.3
2 1 1.7
3 7 11.7
4 1 1.7
5 3 5.0
Ray (missing = 1)
0.0
1 1 1.7
2 0 0.0
3 0 0.0
4 0 0.0
5 1 1.7 % derived using denominator 60 (number of upper limb infection)
30
Table 8.10: Current upper limbs infections (culture, operations during admission
and clinical outcome), Diabetes Foots and Hands, National Orthopadic Registry
Malaysia (NORM) 2009
Infections Total
n %*
Clinical outcome
Wound healed by itself
0 0.0
Split skin grafting 37 61.7
Wound clean, granulate
2 3.3
Wound covered 0 0.0
Amputation, healed 0 0.0
Amputation, infected 0 0.0
Death, due to septic 1 1.7
Death, due to medical 1 1.7
Discharged at own risk
0 0.0
% derived using denominator 60 (number of upper limb infection)
Section 9: Current Lower Limbs Infections
Table 9.1: Current lower limbs infections (infections and location), Diabetes Foots
and Hands, National Orthopadic Registry Malaysia (NORM) 2009
Infections Total
n %*
Infections (no = 51, na = 5)
1198 100.0
Digit
1 274 22.9
2 176 14.7
3 152 12.7
4 139 11.6
5 128 10.7
Plantar, metatarsal 342 28.5
Dorsum 338 28.2
Plantar, heel area 180 15.0
Ankle: medial 66 5.5
Ankle: Lateral 70 5.8
Thigh 27 2.3
Leg 104 8.7
31
Web space
1st 95 7.9
2nd 80 6.7
3rd 63 5.3
4th 76 6.3
Amputation stump
Below knee 86 7.2
Above knee 16 1.3
Syme’s 1 0.1
Transmetatarsal 29 2.4
Hip 0 0.0 % derived using denominator 1198 (number of lower limb infection)
Table 9.2: Current lower limbs infections (diagnosis and classification), Diabetes
Foots and Hands, National Orthopadic Registry Malaysia (NORM) 2009
Infections Total
n %*
Diagnosis
Cellulitis 150 12.5
Paronychia 5 0.4
Abscess 293 24.5
Ulcer 522 43.6
Gas gangrene 21 1.8
Dry gangrene 117 9.8
Wet gangrene 160 13.4
Necrotising fasciitis 76 6.3
Osteomyelitis 283 23.6
Others 18 1.5
Stage
A 75 6.3
B 218 18.2
C 65 5.4
D 63 5.3
Grade
0 31 2.6
1 207 17.3
2 124 10.4
3 65 5.4 % derived using denominator 1198 (number of lower limb infection) See appendix 4 for details of others diagnosis
32
Table 9.3: Current lower limbs infections (associated complications, precipitating
factor and physical findings), Diabetes Foots and Hands, National Orthopaedic
Registry Malaysia (NORM) 2009
Infections Total
n %*
Associated complications
Nil 1033 86.2
Septicaemia 75 6.3
Pneumonia 9 0.8
Stroke 13 1.1
UGIB 2 0.2
Renal failure 75 6.3
CCF 3 0.3
Pressure sores 6 0.5
Precipitating factor 0.0
Spontaneous 433 36.1
Minor trauma 407 34.0
Major trauma 10 0.8
Insect bite 10 0.8
Animal bite 10 0.8
Work related 20 1.7
Recreational related 7 0.6
Latrogenic 12 1.0
Others 40 3.3
Unknown 266 22.2
Physical findings 0.0
Palpable dorsalis 890 74.3
Palpable posterior 888 74.1
Periph. neuropathy 363 30.3 % derived using denominator 1198 (number of lower limb infection) See appendix 5 for details of others diagnosis
33
Table 9.4: Current lower limbs infections (culture), Diabetes Foots and Hands,
National Orthopadic Registry Malaysia (NORM) 2009
Infections Total
n %*
Culture:
1st culture
No growth 332 27.7
Mixed growth 162 13.5
Single growth 375 31.3
Mixed growth
Acinetobacter 32 2.7
Anaerobic 3 0.3
Bacteroides 2 0.2
Coagulase 5 0.4
Enterococcus 14 1.2
Enterobacter 34 2.8
Escherichia 51 4.3
Klebsiella 75 6.3
Proteus 90 7.5
Serratia 2 0.2
Pseud. aeruginosa 99 8.3
Pseud. spp 12 1.0
Staphylococcus 67 5.6
B-hemolytic strep. 22 1.8
Viridans strep. 4 0.3
Others 129 10.8 % derived using denominator 1198 (number of lower limb infection) See appendix 6 and 7 for details of mixed growth
34
Table 9.5: Current lower limbs infections (operations during admision), Diabetes
Foots and Hands, National Orthopadic Registry Malaysia (NORM) 2009
Infections Total
n %*
Operation during admission
Nil 198 16.5
Amputation 405 33.8
Wound debridement 712 59.4
Bypass surgery 0 0.0
Amputation
Disarticulation 81 6.8
Ray 242 20.2
Transmetatarsal 8 0.7
Syme’s 2 0.2
Below knee 105 8.8
Through knee 1 0.1
Above knee 21 1.8
Hip disarticulation 2 0.2
Not available 0 0.0
Disarticulation
1 33 2.8
2 27 2.3
3 21 1.8
4 20 1.7
5 11 0.9
Ray 0 0.0
1 82 6.8
2 72 6.0
3 62 5.2
4 51 4.3
5 60 5.0 % derived using denominator 1198 (number of lower limb infection)
35
Table 9.6: Current lower limbs infections (culture, operations during admission and
clinical outcome), Diabetes Foots and Hands, National Orthopadic Registry
Malaysia (NORM) 2009
Infections Total
n %*
Clinical outcome
Wound healed by itself
126 10.5
Split skin grafting 17 1.4
Wound clean, granulate
740 61.8
Wound covered 20 1.7
Amputation, healed 106 8.8
Amputation, infected 13 1.1
Death, due to septic 12 1.0
Death, due to medical 2 0.2
Discharged at own risk
55 4.6
% derived using denominator 1198 (number of lower limb infection)
36
Section 10: Antibiotics
Table 10.1: Antibiotics, Diabetes Foots and Hands, National Orthopadic Registry
Malaysia (NORM) 2009
Antibiotics Duration
0 n (%)
1 – 6 n (%)
7 – 13 n (%)
≥ 14 n (%)
All N (%)*
1. Amikacin 0 (0.0) 1 (33.3) 1 (33.3) 1 (33.3) 3 (0.2)
2. Ampicillin 0 (0.0) 8 (44.4) 8 (44.4) 2 (11.1) 18 (1.2)
3. Ampicillin/Sulbactam 1 (0.1) 256 (36.2) 301 (42.6) 149 (21.1) 707 (46.3)
4. Amoxicillin/Clavulanate 1 (5.0) 13 (65.0) 3 (15.0) 3 (15.0) 20 (1.3)
5.Aztreonam 0 (0.0) 0 (0.0) 1 (100.0) 0 (0.0) 1 (0.1)
6. Cloxacillin 3 (2.7) 52 (46.0) 29 (25.7) 29 (25.7) 113 (7.4)
7. Cephalexin 0 (0.0) 1 (100.0) 0 (0.0) 0 (0.0) 1 (0.1)
8. Cefuroxime 2 (1.0) 74 (35.6) 78 (37.5) 54 (26.0) 208 (13.6)
9. Cefoperazone 0 (0.0) 16 (40.0) 18 (45.0) 6 (15.0) 40 (2.6)
10. Ceftriaxone 0 (0.0) 5 (27.8) 12 (66.7) 1 (5.6) 18 (1.2)
11. Ceftazidime 0 (0.0) 18 (39.1) 17 (37.0) 11 (23.9) 46 (3.0)
12. Ciprofloxacin 0 (0.0) 14 (38.9) 14 (38.9) 8 (22.2) 36 (2.4)
13.Clindamycin 0 (0.0) 2 (33.3) 2 (33.3) 2 (33.3) 6 (0.4)
14. Cotrimoxazole 0 (0.0) 1 (50.0) 0 (0.0) 1 (50.0) 2 (0.1)
15. Fucidic Acid 0 (0.0) 6 (37.5) 2 (12.5) 8 (50.0) 16 (1.1)
16. Gentamicin 0 (0.0) 10 (58.8) 5 (29.4) 2 (11.80 17 (1.1)
17. Imipenem/Cilastatin 0 (0.0) 0 (0.0) 4 (80.0) 1 (20.0) 5 (0.3)
18. Meropenem 0 (0.0) 3 (30.0) 6 (60.0) 1 (10.0) 10 (0.7)
19. Metronidazole 1 (0.6) 74 (43.8) 71 (42.0) 23 (13.6) 169 (11.1)
20. Piperacillin/tazobactam 0 (0.0) 0 (0.0) 4 (57.1) 3 (42.9) 7 (0.5)
21. Rifampicin 0 (0.0) 1 (20.0) 2 (40.0) 2 (40.0) 5 (0.3)
22. Trimethoprim/Sulfamethoxazol 0 (0.0) 0 (0.0) 3 (60.0) 2 (40.0) 5 (0.3)
23. Vancomycin 0 (0.0) 1 (50.0) 1 (50.0) 0 (0.0) 2 (0.1)
24. Sulbactam/Cefoperazone 0 (0.0) 2 (50.0) 2 (50.0) 0 (0.0) 4 (0.3)
Others 0 (0.0) 29 (43.3) 26 (38.8) 12 (17.9) 67 (4.4)
Not Available 0 (0.0) 0 (0.0) 2 (100.0) 0 (0.0) 2 (0.1)
Total 8 (0.5) 587 (38.4) 612 (40.1) 321 (21.0) 1528 *Column percent