Nanometer Resolution Detection
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A typical Fluorescence Image taken by Nikon Eclipse TE2000-U inverted microscope with a 100×/1.40 NA oil objective Nanometer Resolution Detection Nanometer Resolution Imaging and Computational Analysis of Axonal Transport Defects in Drosophila Models of Alzheimer’s Disease Minhua Qiu Department of Biomedical Engineering Advisor: Dr. Ge Yang System Verification Nikon Eclipse TE2000-U inverted microscope Fluorescent beads Nanometer Resolution Piezo Stage 0 nm 8 nm 16 nm Operated by Labview Multi-peak Fitting 0 2 4 6 secs Analysis of Axonal Transport Defects in Fly Models of AD Brain Segment al Nerves Distance: 88 µm Fluoresce nce Imaging APP-YFP vesicle imaged Nanometer Resolutio n Detection Trajector y Recovery Pattern Recogniti on Library of Transport Defects
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Nanometer Resolution Imaging and Computational Analysis of Axonal Transport Defects in Drosophila Models of Alzheimer’s Disease. Minhua Qiu Department of Biomedical Engineering Advisor: Dr. Ge Yang. Analysis of Axonal Transport Defects in Fly Models of AD. Nanometer Resolution Detection. - PowerPoint PPT Presentation
Transcript of Nanometer Resolution Detection
A typical Fluorescence Image taken by Nikon Eclipse TE2000-U inverted microscope with a 100×/1.40 NA oil objective
Nanometer Resolution Detection
Nanometer Resolution Imaging and Computational Analysis of Axonal Transport Defects in Drosophila Models of Alzheimer’s Disease
Minhua QiuDepartment of Biomedical Engineering
Advisor: Dr. Ge Yang
System Verification
Nikon Eclipse TE2000-U inverted microscope
Fluorescent beads
NanometerResolution Piezo Stage
0 nm
8 nm
16 nmOperated by Labview
Multi-peakFitting
0 2 4 6 secs
Analysis of Axonal Transport Defects in Fly Models of AD
Brain Segmental
Nerves
Distance: 88 µm
FluorescenceImaging
APP-YFP vesicle imaged
NanometerResolutionDetection
TrajectoryRecovery
PatternRecognition
Library ofTransport
Defects
