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<Trademark registration No.40-0942873>

What is Nano Disperser?

PNano Disperser, as a brand of Ilshin Autoclave Co., Ltd, which is commonly called High Pressure Homogenizer,

means the technology producing nano-size particle of materials. It is more efficient than other dispersion method

such as Homomixer, Ultrasonic waves, Ball mill.

When Korea was short of the technology about mixture using high pressure dispersion equipments and various prop-

erties of materials, ILSHIN AUTOCLAVE Co.,Ltd managed to develop this dispersion equipments after researching

several times. The Nano Disperser what ensures the stability and efficiency is widely used in several areas.

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● NANO DISPERSER

● High Pressure Homogenizer System

● NH series

● NL series

● Process Test

● Patents

INDEX

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High Pressure Homogenizer System

Pressure Gauge

High Pressure Pump

Inlet

Before After

Outlet

HeatExchanger

CAVITATIONSHEAR FORCEIMPACT

Nozzle Chamber

High Pressure Homogenizer System

Impact Shear Force Cavitation Surface tension, internal friction force in the orifice and shear force in the fluid by viscosity occurs.

When the cavitation bubbles collapse, they force liquid energy to very small volumes, thereby impact between fluid particles occurs.

The cavitations means the behavior of voids or bubbles in a liquid. If energy is increased, then cohesive power between molecules and a void or bubble in a liquid rapidly collapses, producing a shock wave.

With different operation method unlike conventional disperse, crushers or emulsion equipments, it can produce micro particle with 0.01㎛ size. No intrinsic physical property change because of constant pressure and instant treatment method for production process (Uniform particle distribution, complete homogeneous, productivity improvement). It provides improved treatment speed because of continuous input of materials for production.Its distinguishable performance and durability due to self developed diamond micro orifice module. Easy flux control and cleaning of liquid contact section when replacement of materials. Easy operation for repetition test and pressure readjustment. Easy to scale up and down of flux to have continuous process stabilization.

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Particle Size Reduction

Cell Disruption Nano-Encapsulation

Pharmaceutical Multi Layer Ceramic Capacitor (MLCC)

● Emulsions● Suspensions● Liposomes

● E-coil● Yeast

● Polymers● Liposomes● Emulsions

Injectables/ Inhalables/ Parenterals

Omega-3/ Plant Sterols/ Vitamins Cell Disruption/ Vaccines

Soy Milk/ Food Colorings/ Flavorings Inks/ Ceramics/ Polymers/ Carbon Nanotubes

Biotech

Chemical

Electronics Industry

Cosmetic/Nutraceutical

Food

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Ballmill

Stir

Beadsmill

Jetmill

HighPressure

Biology

Chemistry

Ultrasonicwaves

Dispersion

(d) Ultrasonic Disruptor Average Diameter : 66nm

(C) Ultrasonic Bath Average Diameter : 147nm

(a) No Physical Treatment Average Diameter : 585nm(b) Stirrer Average

Diameter : 182nm

Par

ticle

Num

ber

Frac

tion

(%)

Particle Diameter (nm)

(e) High Pressure Homogenizer Average Diamter:45nm

Base Fluid: DI-Water Surfactant: SDS (1,0 wt%)

0100 1000

10

20

30

40

50

60

Applictaiton

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Series Flow Rate Max. Pressure Nozzle type

NH 1000 1L /min 30,000 psi 75 / 100 / 200um <Z/Y>

NH 2000 2L /min 30,000 psi 75 / 100 / 200um <Z/Y>

NH 3000 3L/min 30,000 psi 75 / 100 / 200um <Z/Y>

NH 4000 4L/min 30,000 psi 75 / 100 / 200um <Z/Y>* Can be changed upon customer's requirements

Specification

Size 2,300(D) x 800(W) X 1,500(H)mm

Max.flow rate 4L/min ( @ 30,000psi )

Weight 950kg

Structure Stainless

NH series

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[Patent No. 10-1073382] [Patent No.10-1085873] [Patent No.10-1073380] [Patent No.10-1036945]

NH series

01

02

01 02

Cooling part

Material Supply

Hydraulic System

Chamber

Inlet Reservoir

Control Unit

Nano disperser

This is production scale using hydraulic pressure system. It can work continuously for inner cooling system.

According to pressure and flow, it can be specially manufactured.

Taking account of inner specimen and chemical reaction, multiple materials (PEEK, UHMWPE, PTFE) are used to

make sure the durability.

Reservior tank and auto valve for preventing solidification

Add cooler in intensifier to protect seal

Disassembling of connect-ing parts is easy

Back flashing system for cleaning while chamber is blocked

High pressure homogenizer preventing solidification of materials

High pressure homogenizer with pump head cooler

Cleaning structure & method of high pressure homogenizer

Simple disassembling of plunger and intensifier

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Specification

Size 310(D) x 450(W) X 300(H)mm

Max.flow rate 100ml/min ( @ 22,000psi )

Weight 30kg

Structure Stainless

NL series

* Can be changed upon customer's requirements

Series Flow Rate Max. Pressure Nozzle type

NLM100 100ml/min 22,000 psi 75um <Z/Y>

NLM150 150ml/min 22,000 psi 75um <Z/Y>

NLM200 250ml/min 22,000 psi 75um <Z/Y>

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NL series

Inlet Reservoir

Pressure Gauge

Air Vent Valve

Controller

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To-and-fro motion with screw to pressurize

Intensifier air removement is easy

[Patent No.10-1103011]

Screw type pressure transmitter

[Patent No.10-1073381]

All-in-one pressure transmitter with air vent

This is production scale using hydraulic pressure system. It can work continuously for inner cooling system.

According to pressure and flow, it can be specially manufactured.

Taking account of inner specimen and chemical reaction, multiple materials (PEEK, UHMWPE, PTFE)

are used to make sure the durability.

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Sample Pressure(Number) Effect

Black Lead (Carbon) 2,000kg/㎠ <3pass> Cell destruction & Atomization

CeO2 2,500kg/㎠ <3pass> Dispersion

Raw Materials for cosmetics 1,000kg/㎠ <3pass> Emulsion

Pigment 2,500kg/㎠ <3pass> Dispersion

A high molecular substance 2,500kg/㎠ <3pass> Cell destruction & Atomization

AI2O3 2,000kg/㎠ <3pass> Dispersion

Sample Pressure(Number) Effect

Milk 1,800kg/㎠ <1pass> Dispersion

Soybean Milk 2,000kg/㎠ <5pass> Homogenization

CNT 2,000kg/㎠ <3pass> Dispersion

Water+Oil 2,500kg/㎠ <5pass> Emulsion

CERAMIC 2,000kg/㎠ <5pass> Dispersion

TiO3 2,000kg/㎠ <3pass> Cell destruction & Atomization

Z_Average (d.nm) : 1258 Peak 1 : 1094

Size (d.n...) %Intensity Width(d.n...)

98.2 251.7

Peak 2 : 5560 1.8 0.000

Peak 3 : 0.000 0.0 0.000

Pdi : 0.419

Intercept : 0.966

Result quality Refer to quality report

Size Distnibution by intensity

Inte

nsity

(%)

0.10

5

10

15

20

25

1 10 100 1000 10000

Z_Average (d.nm) : 254.1 Peak 1 : 300.0

Size (d.n...) %Intensity Width(d.n...)

100.0 111.7

Peak 2 : 0.000 0.0 0.000

Peak 3 : 0.000 0.0 0.000

Pdi : 0.148

Intercept : 0.959

Result quality Good

Size Distnibution by intensity

Inte

nsity

(%)

0.10

2

4

6

8

10

12

14

16

1 10 100 1000

Emulsion

Ex) Water + Oil / Water Solubility Cream / Silicone Oil

Ex) CNT(Carbon Nano Tube)/ Cellulose / Pigment

Ex) Carbon black/ Lactose / Titanium Oxide for Cosmetics

Rupture Dispersion

TEST

* Before * After

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[Patent No.10-1168940] High Pressure Disperser for high viscosity materials

[Patent No.10-1146618] Cooling System for High Pressure Disperser and disperser’s nozzle

[Patent No.10-1103011] Screw type pressure transmitter

[Patent No.10-1085873] High pressure homogenizer with pump head cooler

[Patent No.10-1073382] Preventing solidification of raw material

[Patent No.10-1073381] All-in-one pressure transmitter with air vent

[Patent No.10-1073380] Simple disassembling of plunger and intensifier

[Patent No.10-1036945] Cleaning structure & method of high pressure homogenizer

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02 03 04

01

02

03

04

05

06

07

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Patents

Patent

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ILSHIN AUTOCLAVE Co.,Ltd

HeadQuarters (KOREA)

255, Techno 2-ro, Yuseong-gu, Daejeon, Korea (Daedok Techno Valley)Tel: +82-42-931-6100 Fax: +82-42-935-6103

Homepage: www.suflux.com E-mail: webmaster@suflux.com