Names of Principal Investigators involved IAF/MOH IAF... · Web viewThe submission must comprise...

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Name of Lead PI: MO H IAF Category 1 Amount Applying for: Application Form 2013 Ministry of Health Industry Alignment Fund (MOH IAF) Category 1 Application Form 2013 CLOSING DATE : MOH IAF Category 1 is open throughout the year The submission must comprise the endorsed original hardcopy application and its soft copy (in Word & PDF format in a CD). Applications must be submitted to NMRC, MOH, through the Research Office of the Lead Principal Investigator’s (PI’s) Host Institution, to this address: (Attn: Sharon Ling / Jennifer Lee) Ministry of Health Industry Alignment Fund (MOH IAF) National Medical Research Council 11 Biopolis Way #09-10/11 Helios Page 1 of 40

Transcript of Names of Principal Investigators involved IAF/MOH IAF... · Web viewThe submission must comprise...

Page 1: Names of Principal Investigators involved IAF/MOH IAF... · Web viewThe submission must comprise the endorsed original hardcopy application and its soft copy (in Word & PDF format

Name of Lead PI: MOH IAF Category 1Amount Applying for: Application Form 2013

Ministry of Health

Industry Alignment Fund

(MOH IAF)

Category 1

Application Form

2013

CLOSING DATE: MOH IAF Category 1 is open throughout the year

The submission must comprise the endorsed original hardcopy application and its soft copy (in Word & PDF format in a CD). Applications must be submitted to NMRC, MOH, through the Research Office of the Lead Principal Investigator’s (PI’s) Host Institution, to this address:

(Attn: Sharon Ling / Jennifer Lee)Ministry of Health Industry Alignment Fund (MOH IAF) National Medical Research Council11 Biopolis Way#09-10/11 HeliosSingapore 138667

For further enquiries, you may contact Dr Sharon Ling at Sharon_Ling @moh.gov.sg or Ms Jennifer Lee at [email protected].

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Important: Relevant privileged or confidential information should be disclosed to help convey a better understanding of the project. However, such information must be clearly marked in the proposal.

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Name of Lead PI: MOH IAF Category 1Amount Applying for: Application Form 2013

MOH IAF Category 1 Application Form ChecklistPlease ensure that you have completed and included all the items indicated in this checklist below, before submitting your MOH IAF Application Form. Important: Every section/field must be completed. Please indicate “N.A.” if any section/field is not applicable. Incomplete applications will be rejected.

A. Lead PI is advised to familiarize themselves with the following documents before applying:

( ) NMRC Research Grant T&Cs & Finance T&Cs (available from www.nmrc.gov.sg)

( ) Budgeting Requirements – Please refer to the annex of the NMRC Policy Document on Financial Regulations

B. Your Application Form should consist of the following:

( ) 1. Category of Research Proposal

( ) 2. Applicants – CVs of each member of the research team

( ) 3. Title of Research

( ) 4. Field of Research

( ) 5. Abstract

( ) 6. Research Proposal (Limited to 4 pages excluding references) - Attach Annex B, C or D (where applicable)

( ) 7. Ethical Considerations and Containment - Attach copy of the ethics approval (if applicable)

( ) 8. Funding - Attach Research Collaborative Agreement (RCA)

( ) 8.1. Period of Support Requested

( ) 8.2 Funding Request

( ) 8.3 Budget - Manpower, Equipment, OOE and, Details & Justifications for Budget Requested

( ) 9. Milestones/ Timeline

( ) 10. Expected Outcomes

( ) 11. Other support – Attach scientific abstracts of each grant listed in sections (a)-(c), KPIs of currently held NMRC grants and document detailing areas of overlap where applicable (Annex A)

( ) 12. Undertaking by Lead Principal Investigator (PI)

( ) 13. Undertaking by Head of Department (HOD) & Host Institution of Lead PI

C. Submission:

( ) Softcopy application form:Please save as file name asEg. MOH IAF Cat1_5Apr2013_Lead PI Name_Institution Name

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Name of Lead PI: MOH IAF Category 1Amount Applying for: Application Form 2013

( ) Hardcopy application form, with all required signatures and endorsed by corresponding Host Institution's Research Director must be submitted through the Lead PI’s Office of Research or equivalent.

Application for MOH IAF Category 1

All information is treated in confidence. The information is furnished to the National Medical Research Council (NMRC) with the understanding that it shall be used or disclosed for evaluation, reference and reporting purposes. If your application is not successful, this form will be destroyed after the retention period deemed as appropriate by the Council.

1. Category of Research Proposal

a) Please indicate the relevant information if your proposal is a renewal or resubmission. New Submission Renewal (Grant number          ) Resubmission

(Application ID       & No. of resubmissions inclusive of current application     ) Application that has been previously submitted to other NMRC research

grants (Application ID      )

b) Please indicate the suitable category. Preclinical studies Clinical studies Preclinical and Clinical studies

c) Please indicate the suitable category. Individual project Project that is part of a larger Strategic Partnership (made up of multiple

researcher partners and industry partners)

If you checked the second box, please provide the necessary information. Enter NA if not applicable and add more rows if necessary.

Name of Strategic Partnership:

Names of Principal

Investigators involved

Host Institutions

Names of Industry Partners involved

Titles of Projects Relevance/

Comments

2. ApplicantsPlease note that the definitions of a Lead Principal Investigator (Lead PI), Co-Investigator (Co-I) and Collaborator, as indicated in the footnote. Co-Investigators need to hold at least an adjunct position in a local public institution. Researchers from overseas institutions or private companies can only participate as

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collaborators. The terms of collaboration with overseas research institutions and private companies must conform to NMRC’s existing policies.

Name Role in Project (e.g. Principal Investigator1,

Co-I2, Collaborator3,

Industry Collaborator4

Host Institution5

% Effort within

Project6

% Effort Within Own Work

Commitments7

Total 100%

Please attached the CV of each member of the research team. Please use the format below and indicate NA if the required information is not applicable. Please limit to 3 pages.

Name Title NRIC/Passport No. Email Contact No Office Mailing Address Current Position (Please provide full details, e.g. joint appointments; other academic

appointments including those outside of Singapore) Percentage of time spent in Singapore every year Employment History Academic qualifications (Indicate the degree’s title, year of award and name of the institution that

conferred the degree) Research interests Publications in the last 5 years (include only publications of direct relevance to study, stating

impact factors where possible)

1Definition of Lead Principal Investigator (Lead PI): The lead researcher who has the appropriate level of authority and the responsibility to direct the research project being supported by the grant. He or she is responsible and accountable for the proper conduct of the research project.2Definition of Co-Investigator (Co-I): An individual involved in the scientific development and execution of the project. A co-Investigator typically devotes a higher percentage of effort to the project as compared to a collaborator and is considered a key personnel.3 Definition of Collaborator: An individual involved in the scientific development and execution of project. A collaborator would typically devote a specific percent of effort to the project.4 Industry Collaborator are not entitled to receive (directly or indirectly) any portion of the grant.5Definition of Host Institution: the body or institution or administering organization named in the Letter of Award as the “Host Institution” is the body responsible for undertaking and managing the Research and administering the Funding.66 NOTE: Represents percentage effort spent by the team members in the project relative to his/her other team members. The total in this column must add up to 100%.77 NOTE: Represents percentage effort spent by the team members on this project out of total work commitments (e.g. other grants, other teaching and administrative responsibilities, clinical work etc.)

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Name of Lead PI: MOH IAF Category 1Amount Applying for: Application Form 2013

Patents held (related or unrelated to the study) Scientific Awards Half page summary of research outcomes from all previous grants [e.g. publications (full papers

only for the past 5 years and highlight papers that are relevant to the study), patents, awards, etc].

For co-Is and collaborators, please include these two items: Peer reviewed funding awarded as PI in the last 5 years (from local and foreign agencies)

o Grant quantum, start and end date, funding agency and field of research Current and previous support from NMRC or other sources (Please also include proposals

pending approval)

3. Title of Research (Limit to 300 characters)

4. Field of ResearchPlease fill in the Health Research Classification (HRC) System below with reference to the list attached as Appendix 1 in the IRG Guide. The HRC System is adapted from MRC, UK.

(A) Health Category You may select up to 5 categories from the followings. Please use the minimum number of codes to reflect the main focus of the research.

Blood MusculoskeletalCancer NeurologicalCardiovascular Oral and GastrointestinalCongenital Disorders Renal and UrogenitalEar Reproductive Health and ChildbirthEye RespiratoryInfection SkinInflammatory and Immune System StrokeInjuries and Accidents Generic Health RelevanceMental Health OtherMetabolic and Endocrine

(B) Research Activity Code You may select up to 2 sub-codes from the followings, eg, 2.1.

           

1 Underpinning Research

1.1 Normal biological development and functioning 1.2 Psychological and socioeconomic processes1.3 Chemical and physical sciences1.4 Methodologies and measurements1.5 Resources and infrastructure (underpinning)

2 Aetiology

2.1 Biological and endogenous factors2.2 Factors relating to physical environment2.3 Psychological, social and economic factors

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2.4 Surveillance and distribution2.5 Research design and methodologies (aetiology)2.6 Resources and infrastructure (aetiology)

3 Prevention of Disease and Conditions, and Promotion of Well-Being

3.1 Primary prevention interventions to modify behaviours or promote well-being3.2 Interventions to alter physical and biological environmental risks3.3 Nutrition and chemoprevention3.4 Vaccines3.5 Resources and infrastructure (prevention)

4 Detection, Screening and Diagnosis

4.1 Discovery and preclinical testing of markers and technologies4.2 Evaluation of markers and technologies4.3 Influences and impact4.4 Population screening4.5 Resources and infrastructure (detection)

5 Development of Treatments and Therapeutic Interventions

5.1 Pharmaceuticals5.2 Cellular and gene therapies5.3 Medical devices5.4 Surgery5.5 Radiotherapy5.6 Psychological and behavioural5.7 Physical5.8 Complementary5.9 Resources and infrastructure (development of treatments)

6 Evaluation of Treatments and Therapeutic Interventions

6.1 Pharmaceuticals6.2 Cellular and gene therapies6.3 Medical devices6.4 Surgery6.5 Radiotherapy6.6 Psychological and behavioural6.7 Physical6.8 Complementary6.9 Resources and infrastructure (evaluation of treatments)

7 Management of Diseases and Conditions

7.1 Individual care needs7.2 End of life care7.3 Management and decision making7.4 Resources and infrastructure (disease management)

8 Health and Social Care Services Research

8.1 Organisation and delivery of services8.2 Health and welfare economics8.3 Policy, ethics and research governance8.4 Research design and methodologies8.5 Resources and infrastructure (health services)

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5. Abstract In no more than 300 words, concisely describe the specific aims, hypotheses, methodology and approach of the research proposal including its importance to the furtherance of medical science, in particular clinical significance. The abstract must be self-contained so that it can serve as a succinct and accurate description of the research proposal. Note that the scientific abstract may be disclosed to other funding agencies.

6. Research ProposalIn no more than 4 pages (page limit excludes the reference section), please briefly describe the following sections in the research proposal. Please use Arial font size 10 for all text.

Background & Preclinical/Clinical NeedBriefly sketch the background of the research proposed and specifically identify the gaps which the project intends to fill.

Significance, Aims & Hypothesis of projectState concisely the importance of the research described by relating the specific aims in the research proposal and possible long term clinical implications.

Preliminary Studies/Progress report (in no more than 1 page)For NEW APPLICATIONS: -provide an account of the PI’s/Industry’s preliminary studies (if any) pertinent to the applications and/or any other information that will help to establish the importance of the research and the experience and competence of the investigator pursuing the proposed project.

For RESUBMISSION or Applications that have been previously submitted to other NMRC research grants : -in addition to an account of the PI’s/Industry’s preliminary studies, please provide a document itemizing how the current proposal has addressed past reviewers’/panel’s comments, and highlight new features or merits of the current proposal as Annex B; -Please include reviewers’ report of previous unsuccessful application; Rebuttal to the external reviewers; Panel’s comments (where applicable); and Response to the panel (where applicable); Reviewers’ report of previous unsuccessful application as Annex C.

For RENEWAL APPLICATIONS: -Give the beginning and end dates of the period covered since the research project was last reviewed; -Provide a succinct account of published and unpublished results, indicating the importance of the findings; -Discuss any changes in the project’s specific aims during the periods covered; -List the titles and complete references to all publications and completed manuscripts that have resulted from the project;-Submit a progress/final report of the existing project to indicate the progress and outputs of the project in the prescribed NMRC reporting format (i.e. progress/ final report) (Annex D).

Methods/ApproachBriefly the key procedures and approach (in no more than 1 page)

Industry/Commercial Relevance and Intellectual Property Potential Briefly describe any relevance to industry that could lead to commercialisation opportunities, the impact on expanding the local presence of the industry partner, in R&D or related activities, and/or any possibility of intellectual property generated from the project

References

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Name of Lead PI: MOH IAF Category 1Amount Applying for: Application Form 2013

7. Ethical Considerations and ContainmentFund disbursement is subjected to ethics approval if the project involves any of the below.

Please declare the participating institutions where study requiring ethics approval is conducted:

Please tick accordingly if programme involves any of the following:

a) Human Subject Yes No

b) Use of Human Material/ Yes No Animal Tissues or Cells

from Primary Donors (i.e. subject/volunteers recruited for project)

c) Use of Commercially Available Yes NoHuman Material/ Animal Tissues or Cells

d) Animal Experimentation Yes No

e) Requirement for Containment Yes No

f) Multi-centre trial(s) Yes No

(If yes, please state all participating institutions/centres:      )

A copy of the ethics approval is attached Yes No

8. Funding

MOH IAF Cat 1 prerequisite: Industry contribution of 70% or more of the total project costs.NMRC will support the PI on the remaining 30% or less of the total project costs.

Please attach the Research Collaborative Agreement (RCA)The RCA serves as the key supporting document indicating the detailed overall contribution by the PI and industry partner in terms of costs (in-kind or cash), scientific inputs and work scope.

Funding period and amount requested will be based on the RCA.

8.1 Period of Support RequestedUp to a period of 2 years with 1-year extension subject to approval by review panel

Number of years:      

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NUHS Research Office, 14/05/13,
Do not specify NUHS as participating institution; specify either NUS or NUH instead where the study will be conducted.
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8.2 Funding RequestNote that your funding request should be inclusive of the 20% indirect costs.

Funding is capped at SGD 500,000 per project for pre-clinical projects and SGD 1M for clinical projects. For projects involving both pre-clinical and clinical elements, funding will be capped at SGD 1.5M. All the amounts mentioned are inclusive of 20% indirect costs.

Total Amount of Fund Applying for: SGD      

8.3 BudgetPlease list the budget of the funding requested in the format below, and provide the relevant justifications.

Please refer to the annex in the NMRC Policy Document on Financial Regulations for this section. It is also attached to this document as Annex 1.

8.3.1 ManpowerPlease budget for all the manpower required for the project including part-time personnel and those to be shared with other projects. State whether they are existing personnel in your institution or new staff to be recruited. Please use salary scales provided by the Institution or Hospital Administration as a reference. The cost should include annual increments, National Service increment, staff welfare, medical and other related benefits as per the Human Resource policies of your institution.

Staff Category Existing/New No Remarks Total cost

Technologist New                

Research Assistant New                

Research Officer New                

Research Associate New                

Research Nurse New                

Postdoctoral Fellow New                

Visiting Consultant New                

Others:      

(please specify)

New                

Total $0.00

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NUHS Research Office, 14/05/13,
Total amount of fund applying for = Total direct costs + IRC Whereby IRC= (Total direct costs – exceptional items)*100%Kindly refer to the list of exceptional items listed below.Exceptional Items (not taken into account for IRC computation):Major equipment costing more than S$100,000;Intellectual property that is needed to carry out the proposed R&D work;Subcontracting of non-research work (e.g., the development of tools for the research);Payment to volunteers and research patients; andInfrastructural work that is approved (following strong justifications) as a direct cost of the research grant.Kindly reflect the final figure computed in the header of the application form.
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8.3.2 EquipmentPlease budget for all scientific equipment you need to purchase to directly carry out the project. Indicate sharing of equipment with other projects, if any. For equipment costing more than $100,000 each, please indicate the estimated utilization of the equipment (e.g. 70% usage throughout the project period; only 85% usage in the 2nd year for analysis purpose, etc).

Title of Specific Research Theme:

Qty Equipment

Estimated Utilization Rate for Equipment more than $100,000 (to

be justified)

Unit Cost Sub-Total

                     

                     

                     

                     

                     

                     

                     

Total $0.00

8.3.3 Other Operating Expenses (OOE)This category covers other expenses directly related to the project such as the purchase of animals, consumables, laboratory manuals, literature searches, and maintenance of equipment. Conference travel will be funded only if a presentation or an article is presented and is capped at $6,000 per trip per requested year. The presentation or article must be directly related to the project and NMRC’s support must be acknowledged.

Title of Specific Research Theme:

Item Item Description Cost

Materials & Consumables

           

Overseas Travel

           

Others:      

(please specify)

           

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*Please add rows for more items      

Total $0.00

Grand Total: SGD $0.00

8.3.4 Details and Justifications for Budget RequestedPlease provide breakdown for all categories if this is not indicated in the tables.

ManpowerJustifications

EquipmentJustifications

Other Operating Expenses (OOE)JustificationsMaterials & Consumables

Overseas Travel

Others e.g. Singapore Clinical Research Institute (SCRI) cost

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9. Milestones/TimelineProvide the timeline and proposed milestones for the proposal.This section is required for the assessment of the progress of the study and shade the appropriate box(es) to indicate the year and at which quantum of the year of funding that a particular milestone is expected to be met. You can add or delete rows as appropriate.

Note: The proposed milestones will be subjected to review by a post-award committee at the end of each FY during the period of the grant award. The progress of a project is a critical pre-requisite for the continued disbursement of funds.

Research Milestones/ Deliverables Year 1 Year 2 Year 3Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4

1. Lead PI

Milestone 1

Milestone 2

Etc.

2. Co-I

3. Collaborator

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Name of Lead PI: MOH IAF Category 1Amount Applying for: Application Form 2013

10. Expected OutcomesPlease indicate your realistic expectations on the outcomes of this grant. Please state ‘NA’ where indicator is not applicable.

Performance IndicatorsIndicate number /

value

Capability Indicators

Training R&D manpower for industry

Master’s research students trained

PhD students trained

Master’s research and PhD students trained and spun out to local industry as RSEs (Research Scientist & Engineer)

Research staff spun out to local industry as RSEs

Post-doctoral (within 3 years of the PhD award) researchers hired

Developing long term R&D capability *

Joint programs/projects with prestigious international research organizations

Joint programs/projects with local universities

Invention disclosures

Proof-of-concept studies in man

Other Clinical trials

Kick-start clinical treatments/therapeutics

Patents filed

Patents granted

Patents commercialized

Papers published in international journals (To state impact factor)

Presentations at international conferences

Awards for research at national and international level

Industry Relevance Indicators

R&D collaboration *

R&D projects with industry cash funding

Industry dollars received to fund R&D projects

Outcomes *

Revenue from royalties and licensing agreements

Spin-off companies registered

New products or processes commercialized

* NMRC places special emphasis on these targets

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Name of Lead PI: MOH IAF Category 1Amount Applying for: Application Form 2013

11. Other Support Please provide the following details for the grants currently held or being applied for by the Principal Investigator only. Attach additional pages if necessary. Please attach the scientific abstracts of each grant listed below in (a) – (c) and required additional information as Annex A for NMRC’s reference. Missing abstracts / KPIs / attachments will render this application incomplete.

(a) Support from any industry partner(s)Please provide details on the funding/drug(s) or other resources provided by any participating industry partner(s) that the PIs have existing collaboration with.

Items Supported Source of Support

Form of Support

Support Period (Year)In-Kind8

Cash Contribution9

(SGD)

Yes/No

Yes/No

Yes/No

Yes/No

8 Please delete as appropriate

9 Please specify amountPage 14 of 29

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(b) Peer Reviewed Funding Received in the Past 5 years as PI (from local and foreign funding agencies)For Investigator-led grants, e.g. CS-IRG, CBRG, etc, please only include funding awarded in the capacity as a lead PI. For programmatic grants or equivalent grants, e.g. TCR Flagships, B&B, please include only the amount awarded in the capacity as theme PI or Co-PI.

Specifically for NMRC-funded projects, please indicate the NMRC project number and provide the latest research outcomes (Key Performance Indicators) as Annex A.

Title of ResearchFundin

g Agency

Amount of Fund Support

Period (Year)

Expiry Date of the grantApproved/

Received ($)

Balance Available

($)

(c) List all grants applied for (e.g. NMRC, NRF, A*STAR, MOE, Clusters, etc) where outcome is pending

For all NMRC grant applications, please indicate application ID.Please indicate all the grants applied of similar proposal where the applicant and is involved as PI, Co-PI, Co-Investigator or Collaborator and provide any overlapping sections in the proposals as Annex A.

Title of Research and PI’s role in project Application ID

Funding

Agency

Amount of fund applied for ($)

Support Period (Year)

(d) Potential Overlap of Support/ Funding

Please highlight if there is any potential overlap of the above mentioned funding. Note that double-dipping is strictly prohibited. For any overlap, please explain how it would be dealt with.

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12. Undertaking by Lead Principal InvestigatorIn submitting the MOH Industry Alignment Fund (IAF) Category 1 Application, the Project Lead Principal Investigator and all Co-Investigator(s) & Collaborator(s) UNDERTAKE, on any Grant Award, to:

Declare that all information is accurate and true. Declare that he/she is free from any financial conflicts of interest. Not send similar versions or part(s) of this proposal to other agencies for funding. Submit supporting documents of ethics approval obtained from the relevant

Institutional Review Board (IRB) and Animal Ethics Committee for studies involving human subjects/human tissues or cells, and animal/animal tissues or cells respectively, before any funding can be confirmed.

Be actively engaged in the execution of the research and comply with all laws, rules and regulations pertaining to safety, animal and human ethics, including the Singapore Good Clinical Practice guidelines.

Ensure that National Medical Research Council (NMRC) funding is acknowledged in all publications and presentations.

Ensure that all publications arising from research wholly or partly funded by NMRC will be forwarded to NMRC.

Ensure that the requested equipment/resources are not funded by another agency or research proposal.

Ensure that there is a reasonable effort in accessing available equipment/resources within the host institution or elsewhere within Singapore.

Adhere to NMRC’s general guidelines on competitive funding and NMRC’s Terms and Conditions.

------------------------------------------------------Name and Signature of Lead PIDate:

----------------------------------------------------------------Name and Signature of Co-I/Collaborator* 10

Date:

----------------------------------------------------------------Name and Signature of /Co-I/Collaborator*Date:

----------------------------------------------------------------Name and Signature of Co-I/Collaborator*Date:

----------------------------------------------------------------Name and Signature of Co-I/Collaborator*Date:

----------------------------------------------------------------Name and Signature of Co-I/Collaborator*Date:

(*Please add more if required)

13. Undertaking by Head of Department (HOD) & Host Institution of the Lead PI

10 *Delete as appropriatePage 16 of 29

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Name of Lead PI: MOH IAF Category 1Amount Applying for: Application Form 2013

In submitting the Grant Application, the Institution UNDERTAKES, on any Grant Award, to:

Discuss with immediate supervisor of applicant that the following will be complied with:

o The proposed research will be conducted in the host institution o Adequate resources will be provided to the applicant for the entire grant

period (e.g. lab space) o The applicant is independently salaried by the institution for the entire period

of the granto The research abides by all laws, rules and regulations pertaining to national

and the institution's research operating procedures and guidelines o Confirm the accuracy and completeness of information submitted, including

budget, ethics, other funding sources, etc.o Confirm that budget is clear (e.g. no double funding/ excessive purchase of

equipment), and is aligned with host institution HR and other policieso There is no financial conflict of interest

-----------------------------------------------------------Name and Signature of Head of Department11

---------------------------------------------------------Name and Signature of Director of Institution12

---------------Date

---------------Date

11 If the Lead PI is the Head of Department, UNDERTAKING by the HOD’s Reporting officer is required.

12 If the Lead PI is the Director of the Institution, UNDERTAKING by the Director’s Reporting officer is required.

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Annex 1 Budgeting Requirements

MOH IAF Category 1: Funding is capped at SGD 500,000 per project for pre-clinical projects and SGD 1M for clinical projects. For projects involving both pre-clinical and clinical elements, funding will be capped at SGD 1.5M. All the amounts mentioned are inclusive of 20% indirect costs*

*Indirect Research Cost (IRC) is provided to PIs and Host Institutions, up to a maximum of 20% of the direct cost (less exceptional items).

Type of Expenses Description

EOM Related Expenses

Salaries, CPF and fringe benefits including medical, dental, contribution to welfare fund, etc.

Allowable as part of overall compensation to employees provided such costs are incurred under formal established and consistently applied policies of the host Institution.

The manpower funded as part of the direct cost should be directly involved in the research work of the project.

The salaries offered to staffs should be reasonable, in line with local market benchmarks and comply with formal established pay scale of the host Institution that is consistently applied regardless of the source of funds.

Core manpower fundable under the direct cost only:- Research fellow,

- Research engineer/scientist,- Research assistant/associate,

- Specialist laboratory technician,- Biostatisticians,

- Nurses, and- Technical officer.

All other manpower will fall under IRC.

Case by case consideration will be given if the PI can justify that the required manpower should be funded under the direct manpower cost.

Annual leave Allowable for employees. The number of days of leave accorded to staff must be in accordance with formal policies of the host Institution that is consistently applied regardless of the source of funds.

Bonus / Incentive payments,

Allowable as part of a total compensation package, provided such payments are reasonable and are made according to a formal policy of the host Institution that is consistently applied regardless of the source of funds.

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Page 19: Names of Principal Investigators involved IAF/MOH IAF... · Web viewThe submission must comprise the endorsed original hardcopy application and its soft copy (in Word & PDF format

Name of Lead PI: MOH IAF Category 1Amount Applying for: Application Form 2013

Type of Expenses Description

Staff insurance Allowable as part of overall compensation to employees provided such costs are incurred under formal established and consistently applied policies of the host Institution.

Participation of overseas experts

Allowable.

Expenses incurred for overseas experts invited to participate in the project and staying in Singapore for at least 6 months per year must be budgeted separately in the project budget under the category for Visiting Professor/Expert.

For other overseas experts staying for less than 6 months per year, the cost of his/her stay is allowable if the costs are specifically provided for and approved in the project grant.

Examples of such costs are honoraria, salaries, staff relocation, settling-in allowances and other related cost

For staff relocation, settling-in allowances, etc, it will be allowable for senior expatriate R&D staff if the costs are specifically provided for and approved in the project grant.

However, superannuation contributions for such staff are not allowed under both direct cost and IRC.

Staff recruitment and related cost

Not allowable under direct cost. Examples of such costs are advertisement and recruitment agency cost.

These expenses can be claimed under IRC.

Stipends and course fees of full-time and/or part-time graduate research students

Not allowable under both direct cost and IRC.

Only student attachment and top-up for research students are fundable under IRC.

PI’s & co-investigators’ EOM

Not allowable under both direct cost and IRC.

Equipment Related ExpensesNew equipment Allowable if needed specifically for the project.

Each equipment must be individually identified and its total cost Page 19 of 29

Page 20: Names of Principal Investigators involved IAF/MOH IAF... · Web viewThe submission must comprise the endorsed original hardcopy application and its soft copy (in Word & PDF format

Name of Lead PI: MOH IAF Category 1Amount Applying for: Application Form 2013

Type of Expenses Description

inclusive of bank charges, delivery and installation, etc estimated.

For equipment costing more than S$100,000, they will be classified under “Exceptional Items” (see para 2.4 to 2.6 in the Administrative Guidelines). For purchase of such equipment, 3 quotations must be provided in the budget along with full justifications for the need to purchase the equipment.

General purpose IT and communication equipment

Not allowable under direct cost. Examples of such costs are computers, office productivity software, PDAs, mobile phones, etc.

The cost of such equipment can be claimed under IRC. The procurement of such equipment must be reasonable and make according to the formal established and consistently applied policies of the host Institution.

General furniture and office equipment

Not allowable under direct cost. Examples of such costs are fax machines, photocopier machines, workstations and printers, etc.

The cost of such items can be claimed under IRC. All procurement of such items must be reasonable and make according to the formal established and consistently applied policies of the host Institution.

Consumables Related ExpensesConsumables Allowable.

Examples of such costs are supplies and materials, laboratory consumables, animals and drugs which are necessary for the successful execution of the funded project.

All procurement of such items must be reasonable and are made according to the formal established and consistently applied policies of the host Institution.

Drug costs and medical procedures for patients and volunteers

Allowable.

OOE Related ExpensesBank charges Allowable as long as it is specifically related to the payments for

consumables and equipment used in the project.

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Page 21: Names of Principal Investigators involved IAF/MOH IAF... · Web viewThe submission must comprise the endorsed original hardcopy application and its soft copy (in Word & PDF format

Name of Lead PI: MOH IAF Category 1Amount Applying for: Application Form 2013

Type of Expenses Description

Customs and import duties

Allowable as long as it is specifically related to importation of consumables and equipment used in the project.

Books and specialised journals relevant to the research

Allowable.

If the host Institution has a library, books and journals should be obtained from the library and PI should refrain from purchasing the same books or subscribing to such journals.

GST Allowable for expenses incurred for the project.

Local & Overseas conferences

Allowable, if conference is directly relevant to the research area or necessary to accomplish the project objectives for PI, co-investigators, collaborators, researchers and research students funded under the project grant.

The expenses for such conferences may include registration fee for the conference, air tickets, per diem and other allowances. Such payments should be in accordance with the formal policies of the host Institution.

If the conferences are conducted overseas, the travel policy of the host Institution must be consistently adhered to. However, total expenses for travel per trip per person must not exceed $6,000.

The PI must submit a copy of the abstract when claiming reimbursement for such expenses and append to their annual/ final report.

Photocopying and printing charges

Allowable.

Publications Allowable.

Page charges for publication of manuscript in professional journals are allowable if they adhere to the formal established policy of the host Institution, where applicable.

The costs of reprints and publishing in other media, such as books, monographs and pamphlets are not allowable unless specific approval has been obtained from the NMRC.

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Page 22: Names of Principal Investigators involved IAF/MOH IAF... · Web viewThe submission must comprise the endorsed original hardcopy application and its soft copy (in Word & PDF format

Name of Lead PI: MOH IAF Category 1Amount Applying for: Application Form 2013

Type of Expenses Description

Repairs and maintenance of research equipment

Allowable if specifically budgeted for in the project and the equipment is used extensively for the benefit of the research project.

Stationery & printer consumables

Allowable.

Examples of such costs are printer cartridges, etc.

Training Allowable.

Funding for training is allowable for the PI, co-PIs and the collaborators. For funding of the research personnel, it should be restricted to the personnel employed under the project grant and for training that is of direct benefit and specific to the research project.

Transportation, postage & courier services

Allowable.

This includes postage, courier and freight charges for bringing in equipment and specialised research consumables and reimbursement for staff transportation.

Use of services, equipment rental or lab spaces within the host Institution’s central facilities

Allowable.

The cost for the use of the services and central facilities owned by the host Institution such as animal holding units, central laboratory services are allowable and must be based on host Institution’s fee schedules which are consistently applied regardless of source of funds.

Host Institution may be requested to certify that the fee structure is applied consistently.

Payment to volunteers and research patients and other related cost

Allowable for payment to volunteers and research subjects provided this is the scope of the research and has been provided for and approved in the grant. Examples of such payments may include inconvenience fees, transport and meal reimbursement, etc.

Press advertisements for patients are allowable under IRC only.

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Page 23: Names of Principal Investigators involved IAF/MOH IAF... · Web viewThe submission must comprise the endorsed original hardcopy application and its soft copy (in Word & PDF format

Name of Lead PI: MOH IAF Category 1Amount Applying for: Application Form 2013

Type of Expenses Description

Audit fees Not allowable under direct cost. This includes both internal and external audit fees.

These expenses can be claimed under IRC.

Entertainment & Refreshment

Not allowable under direct cost.

These expenses can be claimed under IRC.

Fines and penalties Not allowable under both direct cost and IRC.

Insurance premiums Not allowable under direct cost. Examples of such costs are for equipment, workmen compensation, professional indemnity of researchers funded under NMRC/NRF grants.

These expenses can be claimed under IRC.

The host Institution is responsible for the insurance of the equipment, relevant workmen compensation and professional indemnity insurance which are in line with the host Institution’s risk policies.

Legal fees Not allowable under direct cost and IRC.

Outsourcing Not allowable under direct cost unless specifically provided for and approved in the grant.

Overhead expenses - rental, utilities, telephone charges, facilities management, repairs and maintenance, etc

Not allowable under direct cost.

These expenses can be claimed under IRC.

Patent-related expenses

Not allowable under direct cost and IRC.

Such cost should be borne by the host Institution.

Professional fees (including fees to

Not allowable under direct cost.

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Page 24: Names of Principal Investigators involved IAF/MOH IAF... · Web viewThe submission must comprise the endorsed original hardcopy application and its soft copy (in Word & PDF format

Name of Lead PI: MOH IAF Category 1Amount Applying for: Application Form 2013

Type of Expenses Description

consultants)

These expenses can be claimed under IRC.

Professional membership fees of PIs /RFs /RAs funded from the grant

Not allowable under direct cost.

These expenses can be claimed under IRC.

Staff retreat Not allowable under direct cost.

These expenses can be claimed under IRC.

Cost of capital works and general infrastructure

Not allowable under direct cost unless specifically provided for and approved in the grant.

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Page 25: Names of Principal Investigators involved IAF/MOH IAF... · Web viewThe submission must comprise the endorsed original hardcopy application and its soft copy (in Word & PDF format

Name of Lead PI: MOH IAF Category 1Amount Applying for: Application Form 2013

Non-Fundable ItemsEOM Related Expenses1 PI’s & co-investigators’ EOM

2 Stipends and course fees of full-time and/or part-time graduate research students

3 Superannuation contributions for senior expatriate R&D staff

OOE Related Expenses4 Fines and penalties

5 Legal fees

6 Patent-related expenses

Others7 Non cash items such as depreciation cost, amortization cost, loss on revaluation, etc.

Exceptional Items (not taken into account for IRC computation):

i. Major equipment costing more than S$100,000;ii. Intellectual property that is needed to carry out the proposed R&D work;

iii. Subcontracting of non-research work (e.g., the development of tools for the research);

iv. Payment to volunteers and research patients; andv. Infrastructural work that is approved (following strong justifications) as a direct cost of

the research grant.

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Page 26: Names of Principal Investigators involved IAF/MOH IAF... · Web viewThe submission must comprise the endorsed original hardcopy application and its soft copy (in Word & PDF format

Name of Lead Applicant: Clinical Trial GrantAmount Applying for: Letter of Intent

APPENDIX

Summary

Item Direct Cost

Indirect Research

CostNon

Fundable

Specifically provided for

and approved in grant

EOM Related ExpensesSalaries, CPF and fringe benefits including medical, dental, contribution to welfare fund, etc. √

Annual leave / Bonus / Incentive payments √

Staff insurance√

Participation of overseas experts√

Student attachment and top-up for research students √

Staff recruitment and related cost√

PI’s & co-investigators’ EOM√

Stipends and course fees of full-time and/or part-time graduate research students √

Superannuation contributions for senior expatriate R&D staff √

Equipment Related ExpensesNew equipment

General purpose IT and communication equipment √

General furniture and office equipment√

Page 26 of 29

Page 27: Names of Principal Investigators involved IAF/MOH IAF... · Web viewThe submission must comprise the endorsed original hardcopy application and its soft copy (in Word & PDF format

Name of Lead Applicant: Clinical Trial GrantAmount Applying for: Letter of Intent

APPENDIX

Item Direct Cost

Indirect Research

CostNon

Fundable

Specifically provided for

and approved in grant

Consumables Related ExpensesConsumables (e.g. supplies and materials, laboratory consumables, animals and drugs) √

OOE Related ExpensesBank charges

Customs and import duties√

Books and specialised journals relevant to the research √

GST√

Local & overseas conferences√

Outsourcing√

Photocopying and printing charges√

Publications√

Repairs and maintenance of research equipment √

Stationery & printer consumables√

Training√

Transportation, postage & courier services √

Use of services, equipment rental or √

Page 27 of 29

Page 28: Names of Principal Investigators involved IAF/MOH IAF... · Web viewThe submission must comprise the endorsed original hardcopy application and its soft copy (in Word & PDF format

Name of Lead Applicant: Clinical Trial GrantAmount Applying for: Letter of Intent

APPENDIX

Item Direct Cost

Indirect Research

CostNon

Fundable

Specifically provided for

and approved in grant

lab spaces within the host Institution’s central facilities

Volunteers and research patients and other related cost √

Press advertisements for patients√

Audit fees√

Entertainment & refreshment√

Insurance premiums√

Overhead expenses (eg. rental, utilities, telephone charges, facilities management, repairs and maintenance, etc)

Professional fees (including fees to consultants) √Professional membership fees of PIs /RFs /RAs funded from the grant √

Staff retreat√

Fines and penalties√

Legal fees√

Patent-related expenses√

Cost of capital works and general infrastructure √

Page 28 of 29

Page 29: Names of Principal Investigators involved IAF/MOH IAF... · Web viewThe submission must comprise the endorsed original hardcopy application and its soft copy (in Word & PDF format

Name of Lead Applicant: Clinical Trial GrantAmount Applying for: Letter of Intent

APPENDIX

Item Direct Cost

Indirect Research

CostNon

Fundable

Specifically provided for

and approved in grant

Others

Non cash items such as depreciation cost, amortization cost, loss on revaluation, etc √

Page 29 of 29