CURRICULUM VITAEDecember 2018

Name: SUSANTA ROYCHOUDHURY, Ph.D., FNA, FASc, FNASc, FAScTJ. C. Bose Fellow

Designation: Chief, Basic ResearchSaroj Gupta Cancer Centre and Research Institute, Kolkata

Former Chief Scientist, CSIR-Indian Institute of ChemicalBiologyFormer Professor, Academy of Scientific and InnovativeResearch (AcSIR)President, Indian Association for Cancer Research

Address: SAROJ GUPTA CANCER CENTRE AND RESEARCH INSTITUTEMahatma Gandhi Road, Thakurpukur, Calcutta - 700063, INDIA

Tel: 91-033-2453-2781/82/83 (Extn 2118) 91-033-2358 1528 (Residence) +919433102986 (Mobile)

Fax: 91-033-2453-6711E. mail : susantarc@gmail.com

Date of Birth: April 20, 1955Marital Status: Married, two childrenCitizenship: IndiaEducation: 1985 Ph.D. (Biochemistry) Calcutta University, India

1977 M.Sc. (Biochemistry) Calcutta University, India1975 B.Sc. (Chemistry) Calcutta University, India

Research Training:

Fellowship:

1987 – 1990 Visiting Postdoctoral Fellow in Molecular Biology University of Pennsylvania, School of Medicine Philadelphia, Pennsylvania, USA

1985 – 1987 Visiting Postdoctoral Fellow in Cell Biology University of Pennsylvania, School of Medicine Philadelphia, Pennsylvania, USA

1984 -- 1985 Research Associate in Genetic EngineeringBose Institute, Calcutta, India

1983 -- 1984 Senior Research Fellow in BiochemistryChittaranjan National Cancer Institute, Calcutta, India

1979 -- 1983 Junior Research Fellow in BiochemistryChittaranjan National Cancer Institute, Calcutta, India

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Experience:

2015 – cont Clinical cancer research

2009 – cont Chemoresistance in cancer

2001 – cont Genomic instability in cancer

2003 (Aug. – Oct.) Cytogenetic analysis of the involvement of 11q13 amplicon in anaphase bridge formation in oral squamous cell carcinoma by FISH

2002-2012 Genetic susceptibility to Helicobacter pylori associated human diseases

1998 – cont. Molecular Genetics of Head and Neck Cancer,

1998 – 2008 Genetic Diversity of Indian Population

1991 -- 1998 Molecular Biology of Vibrio choleraeWhole genome mapping

1987 – 1991 Molecular Biology of Human Hepatitis B virus.Mutational analysis of viral genes [Dr. Chiaho Shih]

1985 – 1987 Cell Biology of Peptide Growth Factor [Dr. Manjusree Das]

1984 – 1985 Characterization of S1 – hypersensitive sites in r-DNA of Drosophilamelanogester [Dr. R. K. Mondal]

1979 – 1984 Interaction of anthracycline anti-tumor drugs with mammalian cell membrane [Dr. R. K. Neogy]

Professional Appointments:

2015- Chief, Basic Research, Saroj Gupta Cancer Centre and Research Institute

2011 --2015 Scientist G, Indian Institute of Chemical Biology2006 -- 2011 Scientist F, Indian Institute of Chemical Biology2002 -- 2006 Scientist EII, Indian Institute of Chemical Biology1998 -- 2002 Scientist EI, Indian Institute of Chemical Biology1993 -- 1998 Scientist C, Indian Institute of Chemical Biology1991 – 1993 CSIR Pool Scientist, Indian Institute of Chemical Biology

Institutional Responsibilities: Head, Molecular Diagnostic Facility

Thesis Supervised: Ph. D Twenty-one (21)M.V.Sc. One

Present Ph.D. students: Three (03)

Awards / Honors:1972 –1975 Awarded Merit Scholarship from the Government of West Bengal, India2003 (Aug. – Oct.) Fogarty Visiting Faculty Fellow, Department of Human Genetics,

University of Pittsburgh, USA

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2006-2011 Advisor, Public Health, West Bengal Council for Science and Technology, Govt. of West Bengal

2008-2011 Secretary, Society of Biological Chemists (India), Kolkata Chapter2008-2012 Secretary, Calcutta Consortium of Human Genetics, Kolkata2009 Member, Core Group of CSIR scientists for the Indo-Japan

Collaboration on research on Systems Biology2009 Fellow, National Academy of Sciences, India2009 Fellow, West Bengal Academy of Science and Technology2011-2013 Executive Committee Member, Indian Society of Human Genetics2012-2015 Executive Committee Member, National Academy of Science, India.

Kolkata chapter2013-2014 Executive Committee Member, Indian Association for Cancer

Research2014 Fellow, Indian Academy of Sciences2014-2017 Task Force Member, Human Genetics and Genomics,

Department of Biotechnology, Govt. of India2014-2017 Task Force Member, Genome Engineering and Application,

Department of Biotechnology, Govt. of India2016-2018 President, Indian Association for Cancer Research2017 Fellow, Indian National Science Academy2017 J C Bose Fellow, Department of Science & Technology, Govt. of

India2018- Advisor, National Academy of Science, India. Kolkata chapter2018- President, Society of Biological Chemists (India), Kolkata Chapter

Journal Editorial Boards:

2003- Member, Editorial Board, International Journal of Human Genetics2009- Member, Editorial Board, World Journal of Gastrointestinal

Oncology, Baishideng Press2011- Editorial Board Advisor, Indian Journal of Human Genetics2014- Editorial Board Member, Scientific Reports, npg Publications2016- Associate Editor, World Journal of Medical Genetics

Meetings organized:September 2017 Joint Org. Secretary, 4th International Conference on Angiogenesis

Research: Anti-Angiogenic Therapy in Human Diseases, 21st September 2017

January 2017 Org. Secretary, 8th East Zonal Oncology Symposium, 21st January 2017

March 2013 Convener, Transcription Meeting 2013, 3-5 March 2013November 2012 Convener, Guha Research Conference 2012, Nov 28 to Dec 02, 2012February 2011 Organizing Secretary, 30th Annual Convention of Indian Association

for Cancer Research & International Symposium on "Signaling Network and Cancer" 6 -9 February 2011

January 2010 Convener, Annual discussion meeting, Molecular Immunology Forum

February 2009 Secretary, International Symposium on Systems Biology and Proteomics

August 2008 Secretary, Satellite conference of Human Genome MeetingFebruary 2007 Joint secretary, Annual Meeting of Indian Society of Human

Genetics

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Teaching Activities: Cancer Genetics course in M. Sc. (Bio-Technology) curriculum of

Calcutta University (10 lectures, each 2hr duration)

Cancer Genetics course in M. Sc. (Microbiology) curriculum of Calcutta University (10 lectures, each 2hr duration)

Cell Biology course in M. Sc. (Biophysics, Molecular Biology & Genetics) curriculum of Calcutta University (10 lectures, each 2hr duration)

Cancer Genetics course in M. Sc. (Molecular Biology) curriculum of West Bengal University of Technology (10 lectures, each 2h duration)

Cancer Genetics course in M. Sc. (Genetics) curriculum of Calcutta University (6 lectures, each 2hr duration)

Molecular Biology course in M. Pharm curriculum of National Institute of Pharmaceutical Education and Research-Kolkata (NIPER-KOLKATA) (10 lectures, each 1hr duration)

Other Activities: Peer Reviewer, International Scientific Journals, e.g Cancer

Prevention and Detection, Oral Oncology, American Journal of Gastroenterology, Journal of Genetics, PLoS ONE, European Journalof Cancer etc.

Expert, Technical committees, Bose Institute, Anthropological Survey of India, National Institute of Biomedical Genomics

Member, Faculty Selection Committee, National Institute of Biomedical Genomics

Member, Human Ethical Committee, Saroj Gupta Cancer Centre and Research Institute

Chairman, Human Ethics Committee, Bose Institute

Professional Membership:Life Member Society of Biological Chemists (India)Life Member Indian Society of Cell BiologyLife Member Indian Association for Cancer ResearchLife Member Indian Society of Human GeneticsMember Human Genome Organization (HUGO)Member Guha Research Conference (GRC)Member Molecular Immunology Forum (MIF)

Major Research Interest: Genetics of Complex Human Diseases

Research Support:

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ONGOING:

Funding Agency: Science Engineering Research BoardFunding Period: 2017 – 2019Role: Principal InvestigatorTitle: J C Bose National Fellowship

Funding Agency: Science Engineering Research BoardFunding Period: 2018 – 2020Role: Principal InvestigatorTitle: Delineating Transcriptional Role of APC/CCdc20 Complex and its

impact on Chromosome Instability in Oral Cancer

COMPLETED

Funding Agency: Council of Scientific and Industrial ResearchFunding Period: 2011 – 2016Role: Principal InvestigatorTitle: NMITLI project on “Discovery and Validation of New

Biomarkers for Head & Neck Cancer in India”

Funding Agency: Council of Scientific and Industrial ResearchFunding Period: 2012 – 2017Role: Principal InvestigatorTitle: “Role of mutant p53 target gene EFNB2 in human cancer: a

chemical biology approach to overcome drug resistance” underMayo Clinic-CSIR Collaboration for Innovation and Translational Research

Funding Agency: Department of Science and Technology, Govt. of India Funding Period: 2011 – 2014Role: Principal InvestigatorTitle: Identification of candidate tumor suppressor genes loci in

chromosomes 3, 4 and 11 associated with the development ofuterine cervical carcinoma.

Funding Agency: Council of Scientific and Industrial ResearchFunding Period: 2010 – 2013Role: Nodal ScientistTitle: Multi-agent therapy of cancer: A systems biology approach

Funding Agency: Council of Scientific and Industrial ResearchFunding Period: 2007 – 2012Role: Nodal ScientistTitle: New insights in cancer biology: identification of novel targets and

development of target based molecular medicine

Funding Agency: Department of BiotechnologyFunding Period: 2006 - 2011

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Role: Principal InvestigatorTitle: Identification of new molecular targets for the development of anti-

cancer agents.

Funding Agency: Department of BiotechnologyFunding Period: 2006 - 2010Role: Principal InvestigatorTitle: Identification of susceptibility alleles for the development of head

and neck cancer in Indian population

Funding Agency: Council of Scientific and Industrial ResearchFunding Period: 2002 – 2007Role: Principal InvestigatorTitle: Toxicogenomics of polymorphism in Indian population to

industrial chemicals for development of biomarkers

Funding Agency: Council of Scientific and Industrial ResearchFunding Period: 2002 – 2007Role: Principal InvestigatorTitle: Predictive medicine using repeat and single nucleotide

polymorphisms

Funding Agency: Indian Council of Medical research, Govt. of IndiaFunding Period: 2002 – 2005Role: Principal InvestigatorTitle: Characterization of Cytokine Gene Polymorphism in Helicobacter

pylori Infected Indian Population

Funding Agency: Department of Biotechnology, Govt. of India Funding Period: 1999 – 2002, extended up to 2003Role: Principal InvestigatorTitle: Molecular analysis of the development of head and neck squamous

cell carcinoma

Funding Agency: Department of Biotechnology, Govt. of India Funding Period: 2000 – 2003Role: Principal InvestigatorTitle: Human Genome Diversity Interlink: A Network Study of Genomic

and Mutational Diversities in Indian Population

Funding Agency: Department of Biotechnology, Govt. of IndiaFunding Period: 1997 – 2000Role: Principal InvestigatorTitle: Genomic diversity in Indian population: Investigations through

biotechnological tools in Eastern Indian population

Funding Agency: Department of Biotechnology, Govt. of IndiaFunding Period: 1996 – 1999Role: Principal InvestigatorTitle: Identification of Vibrio cholerae genes by random cloning and

sequencing

Funding Agency: Department of Biotechnology, Govt. of India

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Funding Period: 1995 – 1998Role: Principal InvestigatorTitle: Mapping of the complete genome of Vibrio cholerae

Original Research Papers:

1. Roychoudhury, S., Deb, J.K., Choudhury, K. and Neogy, R.K. Inhibition of uridine transportthrough Sarcoma-180 cell membrane by anthracycline antibiotics. Biochem. Pharmacol. 32:1811-1814 (1982)

2. Chianese, D., Roychoudhury, S., Murthy, U., Sen Mazumder, A., Earnest, C. and Das,M.Cell and tissue-specific expression of a 34,000 dalton molecular weight peptide growth factorin humans. Human Pathology 19: 190-194 (1988)

3. Roychoudhury, S., Sen Mazumder, A., Murthy, U., Mishra, V.S., Klinman, H.J., Nestler,J.E., Strauss, F. and Das, M. Biosynthesis and turnover of a 34 kDa protein growth factor inhuman cytotrophoblasts. Eur. J. Biochem. 172: 777-783 (1988)

4. Roychoudhury, S., Mishra, V.S., Low, M.G. and Das, M.. A phospholipid is the membrane-anchoring domain of a protein growth factor of molecular mass 34 kDa in placentaltrophoblasts. Proc. Natl. Acad. Sci. USA 85: 2014-2018 (1988)

5. Das, M., Chauhan, S.S., Mishra, V.S., Sanger, J.M., Sanger, J.W. and Roychoudhury, S.Aberrant post-endocytotic fate of a 34,000 dalton molecular weight growth factor fromtrophoblasts. Cancer Res. 49: 2761-2765 (1989)

6. Shih, C., Li, L.S., Roychoudhury, S. and Ho, M.H. In vitro propagation of human hepatitis Bvirus in rat hepatoma cell line, Proc. Natl. Acad. Sci. USA, 86: 6323-6327 (1989)

7. Roychoudhury, S. and Shih, C. Cis Rescue of a mutated reverse transcriptase gene of humanhepatitis B virus by creation of an internal ATG. J. Virol. 64: 1063-1069 (1990)

8. Roychoudhury, S., Faruqi, A.F. and Shih, C. Pregenomic RNA encapsidation analysis ofeleven missense and nonsense polymerase mutants of human hepatitis B virus. J. Virol. 65:3617-3624 (1991)

9. Faruqi, A.F., Roychoudhury, S., Greenberg, R., Israel, J. and Shih, C. Replication-defectivemissense mutations within the terminal protein and spacer/intron regions of the polymerasegene of human hepatitis B virus. Virology, 183: 764-768 (1991)

10. Ghosh, B., Datta, U., Roychoudhury, S. and Mandal, R.K. Size class homology of repeatlengths and evolutionary divergence of ribosomal RNA genes in fishes as studied byrestriction fragment length analysis. J. Genet. 70: 169-179 (1991)

11. Roychoudhury, S., Bhadra, R.K. and Das, J. Genome size and restriction fragment lengthpolymorphism analysis of Vibrio cholerae strains belonging to different serovars andbiotypes. FEMS Microbiol. Lett. 115: 329-334 (1994)

12. Bhadra, R.K., Roychoudhury, S. and Das, J. Vibrio cholerae O139 El Tor biotype. Lancet,343: 728 (1994)

13. Bhadra, R.K., Roychoudhury, S.,* Banerjee, R.K., Kar, S., Majumdar, R., Sengupta, S.,Chatterjee, S., Khetawat, G. and Das, J. Cholera toxin (CTX) genetic element in Vibriocholerae O139. Microbiology, 141: 1977-1983 (1995)

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14. Majumdar, R., Sengupta, S., Khetawat, G., Bhadra, R.K., Roychoudhury, S., and Das, J.Physical map of the genome of Vibrio cholerae 569B and localization of genetic markers. J.Bacteriol. 178: 1105-1112 (1996)

15. Nandi, S., Khetawat, G., Sengupta, S. Majumder, R., Kar, S., Bhadra, R.K., Roychoudhury,S. and Das, J. Rearrangements in the genomes of Vibrio cholerae strains belonging todifferent serovars and biovars. Int. J. Sysm. Bacteriol. 47: 858-862 (1997)

16. Chatterjee, S., Mondal, A. K., Begam N. A., Roychoudhury, S*. and Das, J. Ordered clonedDNA map of the genome of Vibrio cholerae strain 569B and localization of genetic markers.J. Bacteriol. 180: 901-908 (1998)

17. Bhattcharyya, N. P., Basu, P., Das, M., Pramanik, S., Banerjee, R., Roy, B., Roychoudhury,S. and Majumder, P. P. Negligible male gene-flow across ethnic boundaries in India, revealedby analysis of Y-chromosomal DNA polymorphism. Genome Res. 9: 711-719 (1999)

18. Chakrabarti, A., Das S., Majumder, S., Mukhopadhyay, K., Roychoudhury, S. andChaudhuri, K. Use of RAP-PCR figerprinting to identify Vibrio cholerae genes differentiallyexpressed in host following infection. Infect. Immune. 68: 3878-3887 (2000)

19. Das, S.,Chakrabortty, A., Banerjee, R., Roychoudhury, S., and Chaudhuri, K. Comparison ofglobal transcription responses allows identification of Vibrio cholerae genes differentiallyexpressed following infection. FEMS Microbiol. Lett. 190: 87-91 (2000)

20. Basu, P., Chattopadhyay, B., Gangopadhyay, P., Mukherjee, S. C. Sinha, K. K., Das, S. K.,Roychoudhury, S., Majumder, P. P., and Bhattacharyya, N. P. Analysis of CAG repeats inSCA1, SCA2, SCA3, SCA6, SCA7 and DRPLA loci in spinocerebeller ataxia patients anddistribution of CAG repeats at the SCA1, SCA2, and SCA6 loci in nine ethnic populations ofeastern India. Human Genet. 106: 597-604 (2000)

21 Pramanik S., Basu, P., Gangopadhyay, P., Sinha, K. K., Jha, D. K., Sinha, S., Das, S. K.,Maity, B. K., Mukherjee, S. C. Roychoudhury, S., Majumder, P. P., and Bhattacharyya, N.P., Analysis of CAG and CCG repeats in huntingtin gene among HD patients and normalpopulations from India, Eur. J. Hum. Genet. 8: 678-682 (2000)

21. Roychoudhury, S., Roy, S., Dey, B., Chakraborty, M., Roy, M., Roy, B., Ramesh, A.,Prabhakaran, N., Usha Rani, M. V., Vishwanathan, H., Mitra, M., Sil, S. K., Majumder P. P.Fundamental genomic unity of ethnic India is revealed by analysis of mitochondrial DNACurrent Science 79: 1182-1192 (2000)

22. Chakrabarti, S., Dasgupta, S., Roy, S., Bhar, A., Sengupta, A., Roy, A., Ray, K.,Bhattacharyya, N. P., Roy, B., Panda, C. K. and Roychoudhury, S. Microsatellite instabilityin squamous cell carcinoma of head and neck from the Indian patient population, Int. J.Cancer 92: 555-561 (2001)

23. Basu P. Majumder P. P, Roychoudhury S. and Bhattacharyya N. P. Haplotype analysis ofgenomic polymorphisms in and around the myotonic dystrophy locus in diverse populationsof India. Human Genet. 108:310-317 (2001).

24. Roychoudhury, S., Roy, S., Basu A., Banerjee R., Vishwanathan H., Usha Rani, M. V., Sil,S. K., Mitra, M. and Majumder P. P. Genomic structure and population histories oflinguistically distinct tribal groups of India, Human Genet. 109: 339-350 (2001)

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26. Dasgupta, S., Mukherjee, N., Roy, S., Roy, A., Sengupta, A., Roychoudhury, S. and Panda,C. K. Mapping of the candidate tumour suppressor genes’ loci on human chromosome 3 inhead and neck squamous cell carcinoma of Indian patient population. Oral Oncology 38: 6-15 (2002)

27. Basu, A., Mahata, J., Roy, A. K., Sarkar, J. N., Poddar, G., Nandi, A., Sarkar, P. K., Dutta, P.K., Banerjee, A., Das, M., K. Ray, Roychoudhury, S., Nata rajan, A. T., Nilsson, R., Giri, A.K. Enhanced frequency of micronuclei in individuals exposed to arsenic through drinkingwater in West Bengal, India. Mutation Res. 516: 29-40 (2002)

28. Acharya, M., Mitra, S. Mukhopadhyay, Khan, M., Roychoudhury, S, Ray, K. Distribution ofp53 codon 72 polymorphism in Indian primary open angle glaucoma patients . Mol. Vision 8:367-371 (2002)

29 Chakravarty,R., Neiogi, M., Roychoudhury, S., and Panda, C.K. Presence of hepatitis Bsurface antigen mutant G145R DNA in the peripheral blood leukocytes of the familymembers of an asymptomatic carriere and evivence of its horizontal transmission. Virus Res.90: 133-141 (2002)

30. Banerjee, R. and Roychoudhury, S. Analysis of differentially expressed tumour suppressorp53 gene fragment by northern and slot blot hybridization in chineese hamster. Ind. J.Animal Health. 41: 127–133 (2002)

31. Mitra, S., Chatterjee, S. Panda, C.K., Chaudhuri, K., Ray, K., Bhattacharyya, N. P., Sengupta,S. and Roychoudhury, S. Haplotype structure of TP53 locus in Indian population andpossible association with head and neck cancer. Annal Hum Genet 67: 26-34 (2003)

32. Chaudhuri, K. Banerjee, R., Pandit, B., Mukherjee, A., Das, s., Sengupta, S., Roychoudhury,S., and Bhattacharyya, N. P. Identification of two differentially expressed mitochondrialgenes in a methotrexate resistant chineese hamster cell strain derived from V79 cells usingRNA fingerprinting by arbitrary primed polymerase chain reaction (RAP-PCR). RadiationRes. 160: 77-85 (2003).

33. Mondal, G., Tripathi,A., Bhattacharya, N., Sikdar, N., Roy, A., Sengupta,A., Roy, B., PandaC. K. and Roychoudhury, S. Allelic imbalance at chromosome 11 in head and necksquamous cell carcinoma of an Indian patient population. J. Clin Pathol 56: 512-518 (2003)

34. Tripathi, A., Banerjee, S., Roy, A., Roychoudhury, S. and Panda C. K. Alterations of p16genes in uterine cervical carcinoma from Indian patients. Int. J. Gynaecological Cancer 13:472-479 (2003)

35. Chakrabarti, S. B., Dasgupta, S., Roy, A., Sengupta, A., Roy, B., Roychoudhury, S. andPanda, C.K. Differential deletions in chromosome 3p are associated with the development ofhead and neck squamous cell carcinoma from Indian patients. Cancer Genetics andCytogenetics 146: 130-138 (2003)

36. S. Dasgupta, S. B. Chakraborty, A. Roy, S. Roychowdhury and C. K. Panda: Differentialdeletions in chromosome 3p are associated with the development of uterine cervicalcarcinoma in Indian patients. J. Clin. Pathol : Mol Pathol 56: 263-269 (2003)

37. Basu, A., Mukherjee, N., Roy, S., Sengupta S., Banerjee S., Chakraborty M., Badal Dey, RoyM. Roy B., Bhattacharyya N. P., Roychoudhury S. and Majumder P. P. Ethnic India: AGenomic View, with Special Reference to Peopling and Structure. Genome Res. 13: 2277-2290 (2003).

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38. Bhattacharya, N., Tripathi, A., Dasgupta, S., Sabbir, Md. G., Roy, A., Sengupta,A., Roy, B.,Roychoudhury, S. and Panda C. K. Association of deletion in the chromosomal 8p21.3-23region with the development of invasive head & neck squamous cell carcinoma in Indianpatient. Ind. J. Med. Res. 118: 77-85 (2003)

39. Tripathi, A., Banerjee, S., Chunder, N., Roy, A., Sengupta,A., Roy, B., Roychoudhury, S.and Panda C. K. Differential alterations of the genes in CDKN2A-CCND1-CDK4-RB1pathway are associated with the development of head and neck squamous cell carcinoma fromIndian patients. J. Cancer Res and Clin. Oncol 129: 642-650 (2003).

40. Chunder, N., Mandal, S., Basu, D., Roy, A., Roychoudhury, S. and Panda, C.K. Deletionmapping of chromosome 1 in early onset and late onset breast tumors- A comparative study ineastern India. Path. Res. Prac. 199: 313-321 (2003)

41. Chattopadhyay B, Basu P, Gangopadhyay P.K., Mukherjee S.C., Sinha K.K., Chakraborty A.,Roy T., Roychoudhury S., Majumder P.P., Bhattacharyya N.P. Variation of CAG repeatsand two intragenic polymorphisms at SCA3 locus among Machado-Joseph disease/SCA3patients and diverse normal populations from eastern India. Acta Neurol Scand. 108: 407-414 (2003)

42. Gupta A, Neogi R., Mukherjea M., Mukhopadhay A, Roychoudhury, S, Senapati A.,Gangopadhyay P.K., Ray K.DNA linkage based diagnosis of Wilson Disease inasymptomatic siblings. Indian J. Med Res 118: 208-14(2003).

43. Tripathi A., Dasgupta S. Roy A., Sengupta A., Roy B., Roychoudhury S., Panda C. K. Sequentialdeletions in both arms of chromosome 9 are associated with the development of head andneck squamous cell carcinoma in Indian patients.J Exp Clin Cancer Res. 22:289-97 (2003).

44. Chakravorty, M., Ghosh A, Choudhury, A., Santra, A., Hembrum, J. and Roychoudhury, S.Ethnic differences in allele distribution of IL8 and IL1b gene in populations from EasternIndia. Hum. Biol. 76: 153-159 (2004).

45 Chunder N, Mandal S, Roy A, Roychoudhury S, Panda CK Differential association ofBRCA1 and BRCA2 genes with some breast cancer-associated genes in early and late onsetbreast tumors. Ann Surg Oncol. 11:1045-1055 (2004)

46. Chunder N, Mandal S, Roy A, Roychoudhury S, Panda CK. Analysis of different deletedregions in chromosome 11 and their interrelations in early- and late-onset breast tumors:association with cyclin D1 amplification and survival. Diagn Mol Pathol. 13:172-82 (2004)

47. Bhattacharya N., Chunder N., Basu. D, Roy A., Mandal S., Majumdar A., Roychoudhury S,Panda CK. Three discrete areas within the chromosomal 8p. 21.3-23 region are associatedwith the development of breast carcinoma of Indian patients. Exp. Mol. Pathol. 76:264-271(2004)

48. Chunder N.., Roy A., Roychoudhury S, Panda CK Molecular study of clonality in multifocaland bilateral breast tumors. Path. Res. Prac. 200: 735-741 (2004).

49. Bhattacharya N., Singh R.K, Mondal S, Roy A., Mondal R. Roychoudhury S, PandaCK.Analysis of molecular alterations in chromosome 8 associated with the development ofuterine cervical carcinoma of Indian patients. Gynecologic Oncol 95:352-362 (2004).

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50 Mitra, S., Misra, C., Singh, R. K., Panda, C. K. and Roychoudhury, S. Association ofspecific genotype and haplotype of p53 gene with cervical cancer patient in India J. ClinPathol 58: 26-31 (2005)

51. Roychoudhury S, Mitra S. Gene symbol: TP53. Disease: Squamous cell carcinoma of headand neck. Hum Genet. 116: 233 (2005)

52. Singh R.K., Dasgupta S., Bhattacharya N., Chunder N., Mondal R., Roy A., Mandal S.,Roychoudhury S. and Panda C. K. Deletion in chromosome 11 and Bcl-1/Cyclin D1alterations are independently associated with the development of uterine cervical carcinoma JCancer Res Clin Oncol 131:395-406(2005)

53. Mitra S., Sikdar N., Misra C., Gupta S., Paul R. R., Roy B., Panda C. K. and RoychoudhuryS. Risk assessment of p53 genotypes and haplotypes in tobacco associated leukoplakia andoral cancer patients from eastern India. Int J Cancer 117: 786-793 (2005)

54. The Indian Genome Variation Consortium, The Indian Genome Variation database(IGVdb): a project overview, Hum Genet 118: 1-11 (2005)

55. Bhattacharya N, Sabbir MG, Roy A, Dam A, Roychoudhury S, Panda CK Approximately580 Kb surrounding the MYC gene is amplified in head and neck squamous cell carcinoma ofIndian patients. Pathol Res Pract. 201:691-7 (2005).

56. Sabbir M.G., Roy A., Mandal S., Dam A., Roychoudhury S. and Panda C.K. Deletionmapping of chromosome 13q in head and neck squamous cell carcinoma in Indian patients:correlation with prognosis of the tumour. Int J Exp Pathol. 87:151-161 (2006)

57. Chakrabarti S., Sengupta S., Sengupta A., Basak S. N., Roy A., Panda C. K. andRoychoudhury S. Genomic Instabilities in Squamous Cell Carcinoma of Head and Neckfrom the Indian Population. Mol. Carcinogenesis 45: 270-277 (2006).

58. Sabbir MG, Dasgupta S., Roy A., Bhowmik A., Roychoudhury S., Panda CK. Geneticalterations (amplification and rearrangement) of D-type cyclins loci in head and necksquamous cell carcinoma of Indian patients: prognostic significance and clinical implications.Diagn Mol Pathol. 15:7-16 (2006).

59. Mondal G., Boral R. N. and Roychoudhury S. A new Mad2 interacting domain of Cdc20 iscritical for the function of Mad2/Cdc20 complex in the spindle assembly checkpoint.Biochem. J.396: 243-53(2006).

60. Chakravorty M., Ghosh A., Choudhury A., Santra A., Hembrum J., Roychoudhury S.Interaction between IL1B gene promoter polymorphisms in determining susceptibility toHelicobacter pylori associated duodenal ulcer. Human Mutation 27: 411-19(2006)

61. Usha R., Guhathakurta S.; Ghosh S.; Sinha S.; Chatterjee A.; Ahmed S.; Roy Choudhury S.;Gangopadhyay P. K.; Ghosh S.; and Singh M. ; Serotonin Transporter Promoter Variants:Analysis in Indian Autistic and Control Population. Brain Res. 1092:28-35 (2006)

62. De Chaudhuri S., Mahata J., Das J. K., Mukherjee A., Ghosh P., Sau T. J., Mondal L., BasuS., giri A. K. and Roychoudhury S. Association of specific p53 polymorphisms withkeratosis in individuals exposed to arsenic through drinking water in West Bengal, India.Mutation Res. Fundamental Mol. Mech. Mut. 601:102-112 (2006)

63. Banerjee, A., Datta, S., Chandra PK, Roychowdhury, S., Panda CK, Chakravarty R.Distribution of hepatitis B virus genotypes: Phylogenetic analysis and virological

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characteristics of Genotype C circulating among HBV carriers in Kolkata, EasternIndia.World J Gastroenterol. 12:5964-71 (2006)

64. Singh RK, Maulik S, Mitra S., Mondal RK, Basu PS, Roychowdhury S. and Panda CK.Human papillomavirus prevalence in postradiotherapy uterine cervical carcinoma patients:correlation with recurrence of the disease. Int J Gynecol Cancer. 16:1048-54 (2006)

65. Sengupta S., Chakrabarti S., Roy A., Panda C. K. and Roychoudhury S. Inactivation ofhMLH1 and hMSH2 in HNSCC tumors and leukoplakia by promoter hypermethylation and itsrelation with MIN phenotype. Cancer 109:703-712 (2007)

66. Mondal G., Sengupta S., Panda C. K., Gollin S.M., Saunders W. S. and Roychoudhury S.Overexpression of Cdc20 leads to impairment of the spindle assembly checkpoint andaneuploidization in oral cancer. Carcinogenesis 28:81-92 (2007)

67. Reshmi SC, Roychoudhury S., Yu Z., Feingold E., Potter D., Saunders WS. and Gollin SM.Inverted duplication pattern in anaphase bridges confirms the breakage-fusion-bridge (BFB)cycle model for 11q13 amplification. Cytogenet Genome Res. 116: 46-52 (2007)

68. Mitra, S., Banerjee, S., Mishra, C., Singh, R.K., Roy, A., Sengupta, A., Panda, C. K. andRoychoudhury, S. Interplay between Human Papilloma Virus infection and p53 genealterations in head and neck squamous cell carcinoma of an Indian patient population. J. Clin.Pathol 60:1040-1047 (2007)

69. Singh, RK, Indra D., Mitra S., Mondal RK, Basu PS, Roy A, Roychoudhury S and PandaCK. Deletions in chromosome 4 differentially associated with the development of cervicalcancer: evidence of slit2 as a candidate tumor suppressor gene. Hum. Genet. 122:71-81(2007)

70. Indian Genome Variation Consortium, Genetic landscape of the people of India: a canvasfor disease gene exploration. J Genet. 87:3-20. (2008)

71 De Chaudhuri S., Kundu M, Banerjee M, Das JK, Majumdar P, Basu S, Roychoudhury S,Singh KK, Giri AK Arsenic-induced health effects and genetic damage in keratoticindividuals: Involvement of p53 arginine variant and chromosomal aberrations in arsenicsusceptibility Mutation Res: Reviews 659: 118-125 (2008)

72. Sinha S., Chunder N., Mukherjee N., Roy A., Roychoudhury S., and Panda C.K.Frequent deletion and methylation in SH3GL2 and CDKN2A loci are associated with early-and late-onset breast carcinoma. Ann Surg Oncol. 15:1070-80 (2008)

73. De. Chaudhuri S., Ghosh P., Sarma N., Majumdar P., Sau T.J., Basu S., Roychoudhury S., RayK., and Giri A.K. Genetic variants associated with arsenic susceptibility: study of purinenucleoside phosphorylase, arsenic (+3) methyltransferase, and glutathione s-transferase omegagenes. Environ Health Perspect. 116:501-505 (2008).

74. Sinha S, Singh RK, Alam N, Roy A, Roychoudhury S and Panda CK. Frequent alterations ofhMLH1 and RBSP3/HYA22 at chromosomal 3p22.3 region in early- and late-onset breastcarcinoma: Clinical and prognostic significance. Cancer Science 99: 1984-1991(2008)

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75. Ghosh, S., Ghosh, A., Maiti, G. P., Alam, N., Roy, A., Roy, B., Roychoudhury, S. and Panda,C. K.: Chromosomal 3p21.31 region harbors multiple tumor suppressor genes associated withthe development of head and neck squamous cell carcinoma: Correlation with progression andprognosis. Int. J. Cancer 123: 2594-2604 (2008).

76. Sinha SM, Singh RD, Alam ND, Roy AD, Roychoudhury S, Panda CD. Alterations incandidate genes PHF2, FANCC, PTCH1 and XPA at chromosomal 9q22.3 region: Pathologicalsignificance in early- and late-onset breast carcinoma. Mol Cancer. 7: 84 (2008).

77. Ghosh S, Ghosh A, Maiti GP, Alam N, Roy A, Roychoudhury S, Panda CK. Alterations ofROBO1/DUTT1 and ROBO2 loci in early dysplastic lesions of head and neck: clinical andprognostic implications. Hum Genet. 125: 189-198 (2009)

78. Chakravorty, M., Datta De, D., Choudhury A., Santra, A. and Roychoudhury, S.Association of specific haplotype of TNF alpha with Helicobacter pylori-mediated duodenalulcer in eastern Indian population. J. Genetics 87: 299-304 (2008)

79. Ghosh, A., Ghosh, S., Maity GP., Alam, N., Sikdar, N., Roy, A., Roy, B., Roychoudhury, S.and Panda, C.K.: SH3GL2 and CDKN2A/2B loci are independently altered in early dysplasticlesions of head and neck: correlation with HPV infection and tobacco habit. J.Pathol 217:408-419 (2009).

80. Sinharoy, A., Saha, S., Roy Chaudhury, S., and DasGupta M. Transformed hairy roots ofArachis hypogeal: a tool for studying root nodule symbiosis in a non-infection thread legumeof the Asechynomeneae tribe. Mol. Plant-Microbe Int. 22: 132-142 (2009)

81. Misra C., Majumder M., Bajaj S., Ghosh S., Roy B. and Roychoudhury S.Polymorphisms at p53, p73 and MDM2 loci Modulate the risk of Tobacco AssociatedLeukoplakia and Oral Cancer. Mol Carcinogenesis 48: 790-800 (2009)

82. Chakravorty M., Datta De D., Choudhury A., and Roychoudhury S. IL1B promoterpolymorphism regulates the expression of gastric acid stimulating hormone gastrin. Int. J.Biochem. Cell Biol 41:1502-1510 (2009)

83. Banerjee T., Nath S. and Roychoudhury S. DNA damage induced p53 downregulates Cdc20by direct binding to its promoter causing chromatin remodeling. Nucleic Acids Res. 37:2688-2698 (2009)

84. Bhattacharya N, Roy A, Roy B, Roychoudhury S, Panda CK. MYC gene amplificationreveals clinical association with head and neck squamous cell carcinoma in Indian patients.JOral Pathol Med. 38: 759-763 (2009)

85. Klug SJ, Ressing M, Koenig J, Abba MC, Agorastos T, Brenna SM, Ciotti M, Das B, DelMistro A, Dybikowska A, Giuliano AR, Gudleviciene Z, Gyllensten U, Haws AL, HellandA, Herrington CS, Hildesheim A, Humbey O, Jee SH, Kim JW, Madeleine MM, Menczer J,Ngan HY, Nishikawa A, Niwa Y, Pegoraro R, Pillai M, Ranzani G, Rezza G, Rosenthal AN,Roychoudhury S, Saranath D, Schmitt VM, Sengupta S, Settheetham-Ishida W, ShirasawaH, Snijders PJ, Stoler MH, Suárez-Rincón AE, Szarka K, Tachezy R, Ueda M, van der ZeeAG, von Knebel Doeberitz M, Wu MT, Yamashita T, Zehbe I, Blettner M. TP53 codon 72polymorphism and cervical cancer: a pooled analysis of individual data from 49 studies.Lancet Oncol. 10:772-84 (2009)

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86. Mitra S, Mazumder Indra D, Bhattacharya N, Singh RK, Basu PS, Mondal RK, Roy A,Zabarovsky ER, Roychoudhury S, Panda CK. RBSP3 is frequently altered in premalignantcervical lesions: clinical and prognostic significance. Genes Chromosomes Cancer. 49:155-70 (2010)

87. Ghosh S, Ghosh A, Maiti GP, Mukherjee N, Dutta S, Roy A, Roychoudhury S, Panda CK.LIMD1 is more frequently altered than RB1 in head and neck squamous cell carcinoma:clinical and prognostic implications. Mol Cancer. 9:58 (2010)

88. Mitra S, Mazumder Indra D, Basu PS, Mondal RK, Roy A, Roychoudhury S, Panda CK.Amplification of CyclinL1 in uterine cervical carcinoma has prognostic implications. MolCarcinog. 49:935-43 (2010).

89. Ghosh A, Ghosh S, Maiti GP, Sabbir MG, Zabarovsky ER, Roy A, Roychoudhury S, PandaCK. Frequent alterations of the candidate genes hMLH1, ITGA9 and RBSP3 in earlydysplastic lesions of head and neck: clinical and prognostic significance. Cancer Sci.101:1511-20 (2010).

90. Aggarwal S, Negi S, Jha P, Singh PK, Stobdan T, Pasha MA, Ghosh S, Agrawal A; IndianGenome Variation Consortium, Prasher B, Mukerji M. EGLN1 involvement in high-altitude adaptation revealed through genetic analysis of extreme constitution types defined inAyurveda. Proc Natl Acad Sci U S A. 107:18961-6 (2010).

91. Mazumder ' Indra ' D, Mitra S, Singh RK, Dutta S, Roy A, Mondal RK, Basu PS,Roychoudhury S, Panda CK. Inactivation of CHEK1 and EI24 are associated with thedevelopment of invasive cervical carcinoma: Clinical and prognostic implications. Int JCancer. 2010 Dec 10. [Epub ahead of print]

92 Mukherjee N, Bhattacharya N, Sinha S, Alam N, Chakravarti R, Roychoudhury S, PandaCK. Association of APC and MCC polymorphisms with increased breast cancer risk in anIndian population. Int J Biol Markers. 26:43-9 (2011).

93. Haldar S, Roy Choudhury S, Sengupta S. Genetic and functional diversities of bacterialcommunities in the rhizosphere of Arachis hypogaea. Antonie Van Leeuwenhoek J ofMicrobiology. 110: 161-170 (2011)

94. Datta De D, Bhattacharjya S, Maitra M, Datta A, Choudhury A, Dhali GK and RoychoudhuryS. IL1B induced Smad7 negetively regulates gastrin expression. PLoS One. 2011 Mar22;6(3):e14775.

95. Nath S., Banerjee T., Sen D., Das T., and Roychoudhury S. Spindle assembly checkpointprotein Cdc20 transcriptionally activates expression of ubiquitin carrier protein UbcH10, J.Biol. Chem. 286: 15666-15677 (2011)

96. Sinha S, Singh RK, Bhattacharya N, Mukherjee N, Ghosh S, Alam N, RoyA, Roychoudhury S, Panda CK. Frequent alterations of LOH11CR2A, PIG8 and CHEK1 genesat chromosomal 11q24.1-24.2 region in breast carcinoma: clinical and prognosticimplications. Mol Oncol. 5:454-64 (2011).

97. Mazumder Indra D, Mitra S, Roy A, Mondal RK, Basu PS, Roychoudhury S, Chakravarty R, Panda CK. Alterations of ATM and CADM1 in chromosomal 11q22.3-23.2 region are

associated with the development of invasive cervical carcinoma. Hum Genet. 130:735-48 (2011).

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98. Mukherjee N, Bhattacharya N, Alam N, Roy A, Roychoudhury S, Panda CK.Subtype-specific alterations of the Wnt signaling pathway in breast cancer: clinical and prognostic significance. Cancer Sci. 103:210-220 (2012).

99. De Feo E, Simone B, Kamgaing RS, Gallì P, Hamajima N, Hu Z, Li G, Li Y, Matsuo K, Park JY, Roychoudhury S, Spitz MR, Wei Q, Zhang JH, Ricciardi W, Boccia S. p73 G4C14-to-

A4T14 gene polymorphism and interaction with p53 exon 4 Arg72Pro on cancer susceptibility: a meta-analysis of the literature. Mutagenesis. 27:267-273 (2012).

100. Mitra S, Mazumder-Indra D, Mondal RK, Basu PS, Roy A, Roychoudhury S, Panda CK.Inactivation of SLIT2-ROBO1/2 Pathway in Premalignant Lesions of Uterine Cervix:

Clinical and Prognostic Significances. PLoS One. 2012;7(6):e38342. Epub 2012 Jun 13.

101. Ghosh A, Ghosh S, Maiti GP, Mukherjee S, Mukherjee N, Chakraborty J, Roy A, Roychoudhury S, Panda CK. Association of FANCC and PTCH1 with the Development

of Early Dysplastic Lesions of the Head and Neck. Ann Surg Oncol. Jul;19 Suppl 3:528-538 (2012).

102. Nath S, Moghe M, Chowdhury A, Godbole K, Godbole G, Doiphode M, Roychoudhury S.Is Germline transmission of MAD2 gene deletion associated with human foetal loss? Mol

Hum Reprod. 18: 554-562 (2012)

103. Maiti GP, Ghosh A, Chatterjee R, Roy A, Sharp TV, Roychoudhury S, Panda CK.Reduced expression of limd1 in ulcerative oral epithelium associated with tobacco and arecanut. Asian Pac J Cancer Prev. 13:4341-4346 (2012)

104. Madhumita Basu, Tania Das, Alip Ghosh, Subhadipa Majumder, Ardhendu Kumar Maji,Sumana Datta Kanjilal, Indranil Mukhopadhyay, Susanta Roychowdhury, Soma Banerjee,Sanghamitra Sengupta; Gene-Gene Interaction and Functional Impact of Polymorphisms onInnate Immune Genes in Controlling Plasmodium falciparum Blood Infection Level; PLoSONE 2012; 7(10): e46441. [PMID: 23071570]

105. Bhattacharya N, Mukherjee N, Singh RK, Sinha S, Alam N, Roy A, RoychoudhuryS, Panda CK. Frequent Alterations of MCPH1 and ATM are Associated with Primary BreastCarcinoma: Clinical and Prognostic Implications. Ann Surg Oncol. Suppl3:424-432 (2013)

106. Bhattacharjya S., Nath S., Ghose J., Maiti G. P., Panda C. K., Bhattacharyya N. P. andRoychoudhury S. miR-125b promotes cell death by targeting Spindle Assembly Checkpointgene MAD1 and modulating mitotic progression. Cell Death and Differentiation. 20:430-442 (2013)

107. Pinaki Mondal, Sayantan Datta, Guru Prasad Maiti, Aradhita Baral, Ganga Nath Jha,Chinmay Kumar Panda, Shantanu Chowdhury, Saurabh Ghosh, Bidyut Roy and SusantaRoychoudhury. Comprehensive SNP scan of DNA repair and DNA damage response genesreveal multiple susceptibility loci conferring risk to tobacco associated leukoplakia and oralcancer. PLOS ONE February 2013 8(2): e56952. doi:10.1371/journal.pone.0056952

108. Ghosh A, Maiti GP, Bandopadhyay MN, Chakraborty J, Biswas J, RoychoudhuryS, Panda CK. Inactivation of 9q22.3 tumor suppressor genes predict outcome for patientswith head and neck squamous cell carcinoma. Anticancer Res. 33:1215-1220 (2013)

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109. Maiti GP, Mondal P, Mukherjee N, Ghosh A, Ghosh S, Dey S, Chakrabarty J, Roy A, BiswasJ, Roychoudhury S, Panda CK. Overexpression of EGFR in Head and Neck Squamous CellCarcinoma Is Associated with Inactivation of SH3GL2 and CDC25A Genes. PLoS One 2013May 10;8(5):e63440. doi: 10.1371/journal.pone.0063440

110. Datta De D., Datta A., Bhattacharjya S. and Roychoudhury S. NF-kappaB MediatedTranscriptional Repression of Acid Modifying Hormone Gastrin. PLoS ONE August 2013,8(8) e73409; doi:10.1371/journal.pone.0073409

111. Sarkar S., Maiti G P, Jha J., Biswas J., Roy A., Roychoudhury S., Sharp T., Panda C K.Reduction of Proliferation and Induction of Apoptosis are Associated with Shrinkage of Headand Neck Squamous Cell Carcinoma due to Neoadjuvant Chemotherapy. Asian Pac JCancer Prev, 14: 6419-6425 (2013)

112. Tania Das, Kumar Singha Roy, Tulika Chakraborty, Sibabrata Mukhopadhyay,Roychoudhury S. Withaferin A modulates the Spindle Assembly Checkpoint bydegradation of Mad2-Cdc20 complex in colorectal cancer cell lines. BiochemPharmacol 19: 31-39 (2014)

113. Piyal Das, Chetan Kumar Jain, Sanjoy K. Dey, Rajat Saha, Abhishek Dutta Chowdhury,Susanta Roychoudhury, Sanjay Kumar, Hemanta Kumar Majumder and Saurabh Das.Synthesis, crystal structure, DNA interaction and in vitro anticancer activity of a novel Cu(II)complex of purpurin: Dual poison for human DNA topoisomerase I and II. RSC Adv.4:59344-59357 (2014)

114. Chakraborty C, Dutta S, Mukherjee N, Samadder S, Roychowdhury A, Roy A, Mondal RK,Basu P, Roychoudhury S, and Panda CK. Inactivation of PTCH1 is associated with thedevelopment of cervical carcinoma: clinical and prognostic implication. TumourBiol. 36:1143-1154 (2015)

115. Nath S., Chowdhury A., Dey S., Roychoudhury A., Ganguly A., Bhattacharyya D.andRoychoudhury S. Deregulation of Rb-E2F1 axis causes chromosomal instability by engagingthe transactivation function of Cdc20-APC/C complex. Mol. Cell Biol. 35: 356-369 (2015)

116. Dutta S, Chakraborty C, Dutta AK, Mandal RK, Roychoudhury S, Basu P, Panda CK.Physical and methylation status of human papillomavirus 16 in asymptomatic cervicalinfections changes with malignant transformation. J Clin Pathol. 68:206-211(2015).

117. Bhattacharjya S., Singha Roy K., Ganguly A., Sarkar S., Panda C. K., Bhattacharyya D.,Bhattacharyya N. P. and Roychoudhury S. Inhibition of nucleoporin member Nup214expression by miR-133b perturbs mitotic timing and leads to cell death. Mol Cancer 14:42(2015) DOI 10.1186/s12943-015-0299-z .

118. Chakrabortya D. , Maitya A. , Chetan K. Jainb,c, Hazraa A. , Bharitkara Y. P. , Jhad T.,Majumder H. K. , Roychoudhury S. , Mondal N. B. Cytotoxic potential of di-spirooxindolo/acenaphthoquino andrographolide derivatives against MCF7 cell lines. MedChem Comm (2015) DOI: 10.1039/ c4md00469h

119. Maiti GP, Ghosh A, Mondal P, Ghosh S, Chakraborty J, Roy A, Roychowdhury S, PandaCK. Frequent inactivation of SLIT2 and ROBO1 signaling in head and neck lesions: clinicaland prognostic implications. Oral Surg Oral Med Oral Pathol Oral Radiol 119:202-212(2015). doi:10.1016/j.oooo.2014.09.029

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120. Maiti GP, Ghosh A, Mondal P, Baral A, Datta S, Samadder S, Nayak SP, ChakrabartiJ, Biswas J, Sikdar N, Chowdhury S, Roy B, Roychowdhury S, Panda CK. SNP rs1049430in the 3'-UTR of SH3GL2 regulates its expression: Clinical and prognostic implications inhead and neck squamous cell carcinoma. Biochim Biophys Acta. Mol Basis Disease.1852:1059-1067 (2015)

121. Jain CK, Roychoudhury S*, Majumder HK*. Selective killing of G2 decatenationcheckpoint defective colon cancer cells by catalytic topoisomerase II inhibitor. BiochimBiophys Acta. MOL CELL RES 1853:1195-1204 (2015)

122. Dutta S, Chakraborty C, Mandal RK, Basu P, Biswas J, Roychoudhury S, Panda CKPersistent HPV16/18 infection in Indian women with the A-allele (rs6457617) of HLA-DQB1and T-allele (rs16944) of IL-1β -511 is associated with development of cervical carcinoma .Cancer Immunol Immunother. 64:843-851 (2015).

123. Jain C. K., Pradhan B. S., Banerjee S., Mondal N. B., Majumder S. S., Bhattacharyya M.,Chakrabarti S., Roychoudhury S.*, Majumder H. K*. Sulfonoquinovosyl diacylglycerideselectively targets acute lymphoblastic leukemia cells and exerts potent anti-leukemic effectsin vivo. Sci Rep. 5:12082 (2015). doi: 10.1038/srep12082.

124. Datta S, Ray A, Singh R, Mondal P, Basu A, De Sarkar N, Majumder M, Maiti G, Baral A,Jha GN, Mukhopadhyay I, Panda C, Chowdhury S, Ghosh S, Roychoudhury S, Roy B.Mitochondrion. 25:28-33 (2015). doi: 10.1016/j.mito.2015.09.001.

125. Mellerup E, Moeller G L ,  Mondal P , and Roychoudhury S. Combinations of genetic datain a study of oral cancer. Genes & Cancer, 6:422-427 (2015)

126. Mukherjee N, Islam MS, Roychowdhury A, Bhattacharya R, Chunder N, BhattacharyaN, Sinha S, Alam N, Roy A, Roychoudhury S, Panda CK, The stem cell renewal and DNAdamage response pathways are frequently altered in fibroepithelial tumors of breast in Indianpatients, Pathol Res Pract. 212:196-203 (2016). doi: 10.1016/j.prp.2015.12.008.

127. Alam S K, Yadav V K, Bajaj S, Datta A, Dutta S K, Bhattacharyya M, BhattacharyaS, Debnath S, Roy S, Boardman L A, Smyrk T C, Molina J R, Chakrabarti S, ChowdhuryS, Mukhopadhyay D and Roychoudhury S. DNA damage-induced ephrin-B2 reversesignaling promotes chemoresistance and drives EMT in colorectal carcinoma harboringmutant p53. Cell Death & Differentiation, 23:707-722 (2016) doi:10.1038/cdd.2015.133

128. Ghuwalewala S., Ghatak D., Das P. , Dey S., Sarkar S. , Alam N, Panda CK ,Roychoudhury S., CD44highCD24low molecular signature determines the Cancer Stem Celland EMT phenotype in Oral Squamous Cell Carcinoma. Stem Cell Res. 16:405-417 (2016)

129. Datta A., Dey S., Das P., Alam Sk. K., and Roychoudhury S. Transcriptome profilingidentifies genes and pathways deregulated upon Floxuridine treatment in colorectal cancercells harboring GOF mutant p53. Genom Data 8:47-51. (2016) doi:10.1016/j.gdata.2016.03.003.

130. Dutta S, Singh RK, Mandal RK, Roychoudhury S, Basu P, Panda CK. Alteration of HumanPapillomavirus Type 16 Genetic and Epigenetic Profiles in Cervical Cancer Patients IsIndicative of Poor Disease Prognosis: A Cohort Analysis. Int J Gynecol Cancer. 26(4):750-757 (2016). doi: 10.1097/IGC.0000000000000679

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131. Ghosh RD, Ghuwalewala S, Das P, Mandloi S, Alam SK, Chakraborty J, Sarkar S,Chakrabarti S, Panda CK, Roychoudhury S. MicroRNA profiling of cisplatin-resistant oralsquamous cell carcinoma cell lines enriched with cancer-stem-cell-like and epithelial-mesenchymal transition-type features. Sci Rep. 2016 Apr 5;6:23932. doi:10.1038/srep23932

132. Vishal M, Sharma A, Kaurani L, Alfano G, Mookherjee S, Narta K, Agrawal J, BhattacharyaI, Roychoudhury S, Ray J, Waseem NH, Bhattacharya SS, Basu A, Sen A, Ray K,Mukhopadhyay A. Genetic association and stress mediated down-regulation in trabecularmeshwork implicates MPP7 as a novel candidate gene in primary open angle glaucoma.BMC Med Genomics. 9:15 (2016). doi: 10.1186/s12920-016-0177-6

133. Bajaj S, Alam SK, Roy KS, Datta A, Nath S, Roychoudhury S. E2-ubiquitin ConjugatingEnzyme, UBE2C, is Reciprocally Regulated by Wild-type and Gain-of-function Mutant p53.J Biol Chem. 291:14231-14247 (2016)

134. Mukherjee N, Dasgupta H, Bhattacharya R, Pal D, Roy R, Islam S, Alam N, Biswas J, RoyA, Roychoudhury S, Panda CK. Frequent inactivation of MCC/CTNNBIP1 andoverexpression of phospho-beta-cateninY654 are associated with breast carcinoma: Clinicaland prognostic significance. Biochim Biophys Acta. Mol Basis Disease 1862:1472-1484(2016) doi: 10.1016/j.bbadis.2016.05.009.

135. Chakraborty C, Roychowdhury A, Samadder S, Roy A, Mandal RK, Basu P, RoychoudhuryS, Panda CK. Association of P16-RBSP3 inactivation with phosphorylated-RB1 over-expression in basal-parabasal layers of normal-cervix unchanged during CACX development.Biochem J. 473:3221-36 (2016)

136. Bhattacharya R, Mukherjee N, Dasgupta H, Islam MS, Alam N, Roy A, DasP, Roychoudhury S, Panda CK. Frequent alterations of SLIT2-ROBO1-CDC42 signallingpathway in breast cancer: clinicopathological correlation. J Genet. 95:551-563 (2016)

137. Roychowdhury A, Samadder S, Das P, Mandloi S, Addya S, Chakraborty C, BasuPS, Mondal R, Roy A, Chakrabarti S, Roychoudhury S*, Panda CK. Integrative genomicand network analysis identified novel genes associated with the development of advancedcervical squamous cell carcinoma. Biochim Biophys Acta. 1861(1 Pt A):2899-2911 (2017)

138. Dasgupta H, Mukherjee N, Islam S, Bhattacharya R, Alam N, Roy A, RoychoudhuryS, Biswas J, Panda CK. Frequent alterations of homologous recombination repair pathway inprimary and chemotolerant breast carcinomas: clinical importance. Future Oncol. 13:159-174 (2017).

139. Roychowdhury A, Samadder S, Islam MS, Chaudhury K, Roy A, Banerjee D, MandalR, Basu PS, Roychoudhury S, Panda CK. Identification of Changes in the HumanPapilloma Virus 16 (HPV16) Genome During Early Dissemination of Cervical Cancer CellsMay Complement Histological Diagnosis of Lymph Node Metastasis. Pathol OncolRes. 2017 Jan 19. doi: 10.1007/s12253-017-0189-3. [Epub ahead of print]

140. Ray U, Roy Chowdhury S, Vasudevan M, Bankar K, Roychoudhury S, Roy SS.Gene regulatory networking reveals the molecular cue to lysophosphatidic acid-inducedmetabolic adaptations in ovarian cancer cells. Mol Oncol. 11:491-516 (2017)

141. Islam S, Dasgupta H, Roychowdhury A, Bhattacharya R, Mukherjee N, Roy A, MandalGK, Alam N, Biswas J, Mandal S, Roychoudhury S, Panda CK. Study of association and

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molecular analysis of human papillomavirus in breast cancer of Indian patients: Clinical andprognostic implication. PLoS One. Feb 28;12(2): e0172760 (2017)

142. Sarkar S, Alam N, Chakraborty J, Biswas J, Mandal SS, Roychoudhury S, Panda CK.Human papilloma virus (HPV) infection leads to the development of head and neck lesionsbut offers better prognosis in malignant Indian patients. Med Microbiol Immunol. 206:267-276 (2017)

143. Arindam Datta#, Dishari Ghatak#, Sumit Das, Taraswi Banerjee, Anindita Paul,Ramesh Butti, Mahadeo Gorain, Sangeeta Ghuwalewala, Anirban Roychowdhury, SkKayum Alam, Pijush Das, Raghunath Chatterjee, Maitrayee Dasgupta , ChinmayKumar Panda, Gopal C Kundu and Susanta Roychoudhury, p53 gain-of-functionmutations increase Cdc7-dependent replication initiation, EMBO Rep 18:2030-2050.(2017) doi: 10.15252/embr.201643347

144. Islam S, Mazumder Indra D, Basu M, Roychowdhury A, Das P, Dasgupta H, RoyA, Alam N, Mondal RK, Roychoudhury S, Panda CK Phylogenetic analysis ofHuman papillomavirus 16 variants isolated from Indian Breast cancer patients showeddifference in genetic diversity with that of cervical cancer isolates. Virus Res. 243:1-9 (2018)

145. Chakraborty C, Samadder S, Roychowdhury A, Roy A, Das P, Mandal RK, RoychoudhuryS, Panda CK. Activation of Wnt-β-catenin pathway in basal-parabasal layers of normalcervical epithelium comparable during development of uterine cervical carcinoma. Mol CellBiochem. 443:121-130 (2018)

146 Chakraborty C, Mitra S, Roychowdhury A, Samadder S, Dutta S, Roy A, Das P, Mandal RK, Sharp TV, Roychoudhury S, Panda CK. Deregulation of LIMD1-VHL-HIF-1α-VEGF pathway is associated with different stages of cervical cancer. Biochem J. 475:1793-1806 (2018)

147. Sarkar S, Alam N, Mandal SS, Chatterjee K, Ghosh S, Roychoudhury S, Panda CK. Differential transmission of the molecular signature of RBSP3, LIMD1 and CDC25A in basal/ parabasal versus spinous of normal epithelium during head and neck tumorigenesis: A mechanistic study. PLoS One. 2018 Apr 19;13(4):e0195937

148. Dasgupta H, Islam MS, Alam N, Roy A, Roychoudhury S, Panda CK. Induction of HRR genes and inhibition of DNMT1 is associated with anthracycline anti-tumor antibiotic-tolerantbreast carcinoma cells. Mol Cell Biochem. 2018 Sep 3. doi: 10.1007/s11010-018-3442-5. [Epub ahead of print]

149. Mukherjee Chatterjee S., Jain CK., Singha S., Das P., Roychoudhury S., Majumder HK., andDas S. Activity of CoII−Quinalizarin: A Novel Analogue of Anthracycline Based Anticancer Agents Targets Human DNA Topoisomerase, Whereas Quinalizarin Itself Acts via Formation

of Semiquinone on Acute Lymphoblastic Leukemia MOLT-4 and HCT 116 Cells. ACS

Omega 3, 10225-10226 (2018)

150. Dasgupta H, Islam S, Alam N, Roy A,, Roychoudhury S, Panda CK. Hypomethylation of mismatch repair genes MLH1 and MSH2 is associated with chemotolerance of breast

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carcinoma: Clinical significance. J Surg Oncol. 2018 Nov 27. doi: 10.1002/jso.25304. [Epub ahead of print]

*Corresponding author# Equal contribution

Reviews, Monographs, Book Chapters:

1. Roychoudhury, S., Chakrabarti, S., and Mondal, G. Application of Genomic Tools in Cancerresearch, Science and Culture 67: 198-204 (2001)

2. Ray, K., Roychoudhury, S., Senapati, A., Basu, N., and Gangopadhyay, P. K. Recentadvances in Wilson’s disease, Advances in Clinical Neurosciences 11: 247-258 (2001)

3. C. K. Panda, S. B. Chakraborty, A. Tripathi, A. Roy, A. Sengupta, B. Roy and S.Roychowdhury: Analysis of genetic alterations associated with the development of head andneck squamous cell carcinoma from Indian patients, in Tobacco Counters Health, ed A. K.Varma, Vol.2, pp 256-258 (2002)

4. Mondal G. and Roychoudhury S. The Spindle Assembly Checkpoint And Its Defects InHuman Cancer, Int. J. Hum. Genet. 3: 89-97 (2003)

5. Roychoudhury S, and Bhattacharyya N. P. Guest Editor, Special issue on Cancer Genetics and Genomics, International Journal of Human Genetics (2003)

6. Panda C. K. and Roychoudhury S. Molecular Genetics of head and neck squamouscell carcinoma Advances in Genetics and Health, ed. P. Usha Rani, A. Jyothy and M.Hema Prasad, pp 242-247 (2004)

7. Roychoudhury S. and Roy S. Genetic perspective of origin and evolution of Indianpopulation, Science in Archaeology and Archaeo-materials, ed. A. K. Biswas, D. K.Printworld, New Delhi, pp 93-105 (2005)

8. Sengupta S. and Roychoudhury S. DNA double strand break and repair: Mechanismsand involvement in human cancer, Int. J. Hum. Genet. 5: 1-12 (2005)

9. Misra C and Roychoudhury S. p53 gene polymorphism and risk of oral cancer,Perspective in Cytology and Genetics 13:34-42 (2007)

10. Roychoudhury S, Banerjee T, Nath S. CDC20 (cell division cycle 20 homolog (S.cerevisiae)). Atlas Genet Cytogenet Oncol Haematol. 2009; 13(2):104-105.

11. Mandal C, Roychoudhury S, Roy S Cancer research: India meets the West. Cell Death Differ. 18:1675-1677 (2011)

12. Editor special issue on Systems and Synthetic Biology of Science and Culture

13. Bhattacharjya S, Roy KS, Bhattacharyya NP, Roychoudhury S In search of epi-driver genesin head and neck cancer. Mol Cytogenet. 2014 Jan 21;7(Suppl 1 Proceedings of theInternational Conference on Human):I23. doi: 10.1186/1755-8166-7-S1-I23. eCollection2014

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14. Datta De D. and Roychoudhury S. To be or not to be: The host genetic factor and beyond inHelicobacter pylori mediated gastro-duodenal diseases. World J Gastroenterol. 21:2883-2895 (2015).

15. Nath S, Ghatak D, Das P, Roychoudhury S., Transcriptional control of mitosis: deregulationand cancer. Front Endocrinol (Lausanne). 2015 May 5;6:60. doi: 10.3389/fendo.

2015.00060.

16. Jain CK, Majumder HK, Roychoudhury S. Natural Compounds as Anticancer Agents

Targeting DNA Topoisomerases. Curr Genomics. 18:75-92 (2017)

17. Santu Kumar Saha, Guru Prasad Maiti, Susanta Roychoudhury, Chinmay Kumar Panda.Molecular progression of head and neck squamous cell carcinoma. Nucleus 60: 111-119(2017) DOI 10.1007/s13237-017-0212-9

18. Banerjee, S., Chakravarti, D., Ganguli, S. and Roychoudhury, S. Cancer Noncoding RNADiscovery Through High-Throughput Sequencing in Cancer and Noncoding RNAs, ed.Chakrabarti J and Mitra S. Academic Press, Vol. I, pp 463-476, (2018)

Genomic data submission:

1. "Custom array CGH of Oral Squamous Cell Cancer"; Contributor(s): Pinaki M, Prasad MG,Kumar PC, Susanta R; Submission Date: Jan 16, 2014; GEO accession: GSE54165

2. "Mutant p53R273H regulated microRNA profiling in presence and absence of DNA damagein H1299 cells", Contributor(s): Roychoudhury S, Chatterjee R; Submission date: Apr 28,2015; GEO Accession: GSE68353.

3. "Transcriptome profiling of CD44highCD24low (CSC) and CD44lowCD24high (Non-CSC)SCC25 cells", Contributor(s): Sangeeta Ghuwalewala and Dr. Susanta Roychoudhury;Submission Date: Aug 17, 2015; GEO Accession: GSE72118.

4. "Catalogue of genomic alterations in uterine cervical carcinoma of Indian patients",Contributor(s): Roychowdhury A., Samadder S., Roychoudhury S., Panda C.K.Submission Date: Jan 15, 2016; GEO Accession: GSE76911.

5. " Transcriptome profiling of SW480 cells treated or untreated with Floxuridine (FUdR) ";Contributor(s): Roychoudhury S; Submission date: Feb 03, 2016; GEO Accession:GSE77533.

6. “Transcriptome profiling of HepG2 cells in Cdc20 overexpressed and downregulatedcondition”. Contributor(s): Roychoudhury S; Submission date: June 07, 2016; GEOAccession: GSE99756

7. “Global expression profile of uterine cervical carcinoma in Indian patients”; Roychowdhury A, Samadder S, Chatterjee A., Roychoudhury S, Panda CK.. Submission date: :GEO Accession: GSE122697

Patents & Copyrights:

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1. Patent application on “Biomarkers and an in-vitro method for head and neck cancer prognosis” – submitted for provisional patent on 15/05/2018

2. Copyrights on “SIGFEATURE AN R-PACKAGE FOR SIGNIFICANT FEATUR.ESELECTION USING SVM -RFE AND T-STATISTIC” – a computer software. Copyright Registration number: SW- 11544/2018, sanctioned on 03/08/2018

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