Multimodality Imaging of Right Atrial Masses
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Transcript of Multimodality Imaging of Right Atrial Masses
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Journal of the American College of Cardiology Vol. 55, No. 8, 2010© 2010 by the American College of Cardiology Foundation ISSN 0735-1097/10/$36.00P
IMAGES IN CARDIOLOGY
Multimodality Imaging of Right Atrial MassesPatricia Campbell, MD, Robert F. Padera, MD, PHD, Michael M. Givertz, MD
Boston, Massachusetts
Right atrial masssubcostal view →
Right atrialmasses
→↓
Right PA →
← Absent left PA
Main
Filling defect fromright atrial mass →
Right atrial mass �
Bioptome �
H&E Stain WT-1 Stain
C D
BA
E
C1
D Right atrialmass
Bioptome
rom the Cardiovascularivision, Brigham andomen’s Hospital, Harvardedical School, Boston,assachusetts.anuscript receivedpril 22, 2009, acceptedpril 29, 2009.
A76-year-old man presented with 2 months of dyspnea, early satiety, and lower extremityedema. Ten years previously, he underwent left extrapleural pneumonectomy for mesothe-lioma but had chest wall and mediastinal recurrences that required systemic chemotherapy
and local radiation. Transthoracic echocardiography revealed right atrial dilation with a 4.9 � 6.4cm mass attached to the anterior and inferior right atrial walls (A). Cardiac magnetic resonanceimaging demonstrated 2 right atrial masses with gadolinium enhancement indicating vascularity: a5.2 � 4.7 cm mass on the superior free wall, and a 4 � 4 cm mass partially obstructing inferiorvenal caval inflow on the lateral free wall (B). Right ventriculography (C) and echocardiographic-guided biopsy (pulmonary artery) (D) were performed (Online Videos 1, 2, 3 and 4). Histopathol-ogy confirmed the diagnosis of epithelioid-type mesothelioma (hematoxylin and eosin [H&E] stain,E, left; WT-1 stain positive for calretinin, E, right). The patient was not a candidate for surgicalresection and died of progressive metastatic mesothelioma.
ublished by Elsevier Inc. doi:10.1016/j.jacc.2009.04.106