Mt. HoodMt. Hood

IOM Report: IOM Report: 10 Years After & More Coming10 Years After & More Coming

Mitch Greenlick, Ph.D.

Oregon State Representative

April 21, 2010

Bridging the Gap Between Bridging the Gap Between Practice and Research:Practice and Research:

Forging Partnerships with Community-Based Forging Partnerships with Community-Based Drug and Alcohol TreatmentDrug and Alcohol Treatment

Sara Lamb, Merwyn Greenlick, and Dennis McCarty, Editors

Institute of Medicine1998

Findings and RecommendationsFindings and Recommendations

Strategies for:– Linking research and practice– Linking research findings, policy development,

and treatment implementation– Knowledge development– Dissemination and knowledge transfer – Consumer participation– Training for consumer-based research

collaboration

The First RecommendationThe First Recommendation

The National Institute on Drug Abuse and the Center for Substance Abuse Treatment should support the development of an infrastructure to facilitate research within a network of community-based treatment programs.

The Second RecommendationThe Second Recommendation

The National Institute on Drug Abuse and the National Institute on Alcohol Abuse should develop research initiatives to foster studies that include community-based treatment programs as full partners.

Issues Raised by Issues Raised by Recommendation 2Recommendation 2

Include treatment staff in the development of research initiatives and review of proposals

Require assessment of burden of proposed research on treatment program and subjects

Assess relevance and practicality for CBO implementation of proposed research

Require active, early, and permanent participation of treatment staff in the development, implementation, and interpretation of research studies.

What Does the Future HoldWhat Does the Future Hold

Translational research: bench to bedside to community

Community-participatory researchIncreased demand for evidenced-based

practices by policy makersComparative effectiveness researchIncreased recognition of the social costs of

substance abuse.

Translational ResearchTranslational Research

To improve human health, scientific discoveries must be translated into practical applications. Such discoveries typically begin at “the bench” with basic research — in which scientists study disease at a molecular or cellular level — then progress to the clinical level, or the patient's “bedside.”

Comparative Effectiveness Comparative Effectiveness ResearchResearch

Comparative effectiveness research is designed to inform health-care decisions by providing evidence on the effectiveness, benefits, and harms of different treatment options. The evidence is generated from research studies that compare drugs, medical devices, tests, surgeries, or ways to deliver health care

Steps Involved in Comparative Steps Involved in Comparative Effectiveness Research Effectiveness Research

Identify new and emerging clinical interventions. Review and synthesize current medical research. Identify gaps between existing medical research

and the needs of clinical practice. Promote and generate new scientific evidence and

analytic tools. Train and develop clinical researchers. Translate and disseminate research findings to

diverse stakeholders. Reach out to stakeholders via a citizens forum.

Elements of the CTN Produce Elements of the CTN Produce Perfect Setting to Move ForwardPerfect Setting to Move Forward

Community participation in researchMulticenter controlled-trial approachPotential for comparative effectiveness

researchAbility to move into policy transformationTrained researchers and research-trained

treatment personal