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MOTIC VM600 Virtual Microscope MOTIC VM600 Virtual Microscope
Development of Motic’s New Model;Development of Motic’s New Model;Features & Improvements, Model Features & Improvements, Model Strategy, and Model Competition Strategy, and Model Competition
Motic International Dealer MeetingMarch 2009
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Topics CoveredTopics Covered
1. Motic VM Introduction: Hardware & Softwares
2. Application solutions: a. Clinical Diagnosis/b. Consultation, Researchc. Education
3. VM System Operation & software
4. Competitive Analysis
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VM600-4: Digital Slide Scanner
VM: Digital Slide View software
1 、 DPCC( Digital Pathology Digital Pathology Consultation & Communication Consultation & Communication Platform Platform )
2 、 DSS( Digital Slide Server Digital Slide Server System System )
Motic Products Solution
www.moticpathology.com
www.motic.com/dssweb
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4
Motic VM Components (Hardware & Scanning software))
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Scanning
Scanning Process Demo:
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Digital Slide View Demo
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Motic Pro 285 CCD
1. Motic 285A : 2/3 " , 1360 x 1024, 6.45m x 6.45m
MCAM285 Technical Data
Item MCAM285
Sensor Size 2/3"CCD
Resolution 1.4 mega pixels, 1360 X 1024 pixels
Pixel Size 6.45m x 6.45m
Frame Rate 15 fps / second
Shutter Electronic
Dynamic Range >44db S/N
Scanning System Progressive
Minimum Illumination ≈3Lux
USB Interface USB2.0(480Mbit/sec
Voltage DC 5V± 5%
Operating Current ≈260mA
Power Consumption ≈1.3W
Operating Temperature 0℃-50℃Storage Temperature 0℃-60℃Relative Humidity 40%-80%
OS recommended WINDOWS2000 / WINXP / VISTA
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Objective: 20x;Specimen : 10mmx10mm; Scanning Method: Standard; Speed : About 4 min
Scanning Speed
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VM600 Stage Configuration
•X - 272mm ; Y - 196mm ; Z - 93mm ;
•Travel range of 80mm by 24mm
•Stage Accuracy: 1.5625um for x/y –axis,; 0.015um for z-axis;
•Relocation Accuracy: <1um
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Motic VM600 Recommended PC Specifications
Workstation System:•Windows XP Professional •Intel Core(TM) 2 processors•4GB RAM•300GB disk storage
•22 “ Monitor(or larger Optional)
Workstation System:•Windows XP Professional •Intel Core(TM) 2 processors•4GB RAM•300GB disk storage
•22 “ Monitor(or larger Optional)
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Motic VM Scanning Methodology
1. High Precision Auto –Focus every Image , high quality
2. Standard : Build Scanning model , good quality with faster
scanning speeds
3. ROI ( Region of Interest ) : Scan whole slide with low magnification(2x or 4x)
first, then scan ROI with higher magnification . Small Digital slide Size(<10M), useful and convenient for pathology or educational applications (Motic only feature)
4.Multilayer Focus: Multilayer focus and amalgamation each tiled
image . Very high quality ,especially for thick glass slide (but may be too slow for most applications)
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Multilayer Focus Scanning
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Multi-Layer Amalgamation
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Living specimen
FreezesTissue
Traditional Pathology WorkflowTraditional Pathology Workflow
Fix, Dehydrate, Embedding….
Histo-processing Slide Staining
Slides
Surgery Center Pathology Center
Pathologist Center
Pathology Diagnosis
Tissue specimen
Pathology Education
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Digital Slides
Digital Pathology Solution: Adjusting Standard Digital Pathology Solution: Adjusting Standard WorkflowsWorkflows
Living specimen
Fix, Dehydrate, Embedding….
Histo-processing Slide Staining
Tissue specimen
Surgery Center Pathology Center
Freezes Tissue
Pathologist Center
Pathology Diagnosis &Analysis
Slide
Image Analysis
Workflow Management
Remote-Consultation
Education
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•Information Workflow, including Digital Slides…• Integrated Patient records (HIS/PACS…)•Education & Clinical •Remote-Consultation•Image analysis
Future Digital Pathology DirectionsFuture Digital Pathology Directions
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Microscope
MOTIC’s Digital Development Makes the MOTIC’s Digital Development Makes the VM600 The Next Logical Progression …VM600 The Next Logical Progression …
Digital PathologyMicro+Camera
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VM Application SolutionsVM Application Solutions
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VM600 Digital Slide ApplicationsVM600 Digital Slide Applications Educational Educational ((Cell Morphology, Histology, Pathology, etc.)) Digital Slides Classroom Teaching Remote Teaching and Learning Virtual (Web) Teaching Lab for Images view and conference
Clinical Diagnosis(Clinical Diagnosis(PathologyPathology)) Digital Images Data and workflow Management Remote Consultation Digital Slides Conference Aided Diagnosis
ResearchResearch Digital Slides Data TMA Image analysis Pharmaceuticals
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VM Educational ApplicationsVM Educational Applications
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Digital slides Education System for Pathology and Digital slides Education System for Pathology and Histology TeachingHistology Teaching
Classroom Teaching 1. Digital Slides reduce concerns about slide making, loss, breakage or fading; 2. Archive and share critical slides; 3. Built-in Digital Slide information management to reduce teacher prep time for course development and dedicate more time to viewing
Digital slides Testing 1. Manage digital slides to create a test library as an effective means for distributing testing materials; 2. Auto testing
Digital Slides gallery( Web view) 1. Anywhere , anytime access via internet on web, Pre-learning and Review ; 2. Improving the teaching level and learning effectively;
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Motic VMMotic VM
IE ViewIE ViewDSS Server DSS Server
workstation
IE ViewIE View
Motic Digital Slides Server Software SystemMotic Digital Slides Server Software System(DSS)
Lan/Internet
Web-Based
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View by annotation , convenient for teaching and learning
Motic Digital Slides Server SystemMotic Digital Slides Server System(DSS)Web-Based
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Incorporating VM600 with Motic Net as Incorporating VM600 with Motic Net as an effective teaching tool..an effective teaching tool..
Education (VM600 with Motic Net)
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For Pathology Diagnosis (Secondary) & Consultation
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Motic VM Feature: Observe slide by Motic VM whiling or after scanning the slide ,it is the best way for beginning of diagnosing training
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Digital Pathology Consultation & digital slide Communication Platform
LAN or Internet( ADSL)LAN or Internet( ADSL)
Motic VMMotic VM
Remote ExpertsRemote Experts
On business or at homeOn business or at home
LAN or Internet( ADSL)LAN or Internet( ADSL)
DPCC PlatformDPCC Platform
Consultation station
Remote Consultation CenterRemote Consultation Center
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MoticMotic DPCC Platform Web AddressDPCC Platform Web Address
http://www.moticpathology.com
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HIS
PIS
Patient Information Info Management
Workflow
DICOM
Digital Slides
ReportRemote Consultation
Internet)
Conference
Motic VM
Digital Pathology Information WorkflowDigital Pathology Information Workflow
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Competitive AnalysisCompetitive Analysis
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Market Sector CompetitorsMarket Sector Competitors
1. Zeiss Mirax 2. Olympus Bliss HD or .slide3. Aperio 4. Hamamatsu NDP5. Nikon Coolscope6. Claro 7. DMetrix ……
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Zeiss
Mirax DESK(1-slide) Mirax SCAN(300-slide)Mirax MIDI(12-slide)
Objective: Plan-Apochromat 20x/0.8Scan camera: SONY DFW-X710 or others (1/3“inch, 1024 x 768 pixels, cell size
4.65 x 4.65 µm )
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MIRAX Viewer - the virtual microscopeMIRAX MFM - fluorescent slide viewerMIRAX TMA - a powerful tool for high throughput tissue microarray evaluationIH-Lab - software for fast evaluation of immunohistochemistry stained samplesHistoQuant - quantitative and qualitative analysis applicationMIRAX E-School - teaching material authoring tool with exam moduleMIRAX 3D - an application for 3-dimensional reconstruction of serial slidesE-Consult – teleconsultation softwareMIRAX DB - database program for efficient data managementToxicoPath-LIS - application for the management and administration of toxicopathology research
Zeiss (3DHISTECH,Hungarian company)
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Olympus
Dot slide(1-slide/50-slide)
Objectives : 2x PLAPON, 10x, 20x, 40x UPLSAPO, optional, e.g. 100x oilIllumination: brightfield with 100 W halogen lamp house, optional: fluorescence, polarisationDigital CCD camera: 2/3” CCD camera, 6.45 μm x 6.45 μm pixel size
Software functions and modules.View images locally, zoom, crop and rotate images.Net Image Server software for remote access to virtual slides with dotSlide software.Conferencing module for simultaneous and synchronised viewing of virtual slides, conference access control and user management, minute taking tool, chat function.TMA module to acquire individual images of TMA cores
Bacus: Bacus Laboratories,inc., a wholly-owned subsidiary of Olympus America . Founded in 1994, is a leader and innovator in the field of VM.
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NDP: 210-slide
Hamamastu
Objective lens: 20X, NA 0.7 CCD: TDI sensor,4096 x 64 pixel , Line scanning
Software: Developed by other company
Distributed now in the USA through the
Olympus network, approx cost $120K
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Aperio
120-slide
1 -slide 1-slide(Oil)
5-slide
Objective lens: PLAN-APO 20x / 0.75CCD: Line 3-CCD, 1040 x 1 pixel
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NikonCoolScope
CCD:2/3-inch. (total number of pixels: 5.24-mega pixels;effective 5.07-mega pixels)
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Dmetrix
.Objective : Array Micro lens (80)
.The fastest scanning system
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Toco: 1-slide VS0201AS1 : 20-slide VS0801AS1: 80-slide
Claro(Japan)
Objective: Carl Zeiss Aplan 20x, 40xCamera: 1/2 CMOS (1280 x 1024) or 1/2 IT CCD' (1280 x 960)
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Clarient: formed in 1996 to develop and market the ACIS(R) Automated Cellular Imaging System, in cancer diagnostics Sells Its ACIS Instrument Business to Carl Zeiss for $12.5 Million
Following the acquisition of Trestle and of Clarient's equipment business, Carl Zeiss has become the leading provider of solutions for telepathology, digital slides and computer- supported diagnostics with more than 500 installed systems.
Following the acquisition of Trestle and of Clarient's equipment business, Carl Zeiss has become the leading provider of solutions for telepathology, digital slides and computer- supported diagnostics with more than 500 installed systems.
In marketing a clinical version of the system, Carl Zeiss MicroImaging said it is collaborating with the Danish diagnostics company Dako, a manufacturer of reagents for tissue-based cancer diagnosis.
Clarient/Trestle/Dako
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Motic’s Strategic Positioning: Motic’s Strategic Positioning: 1. Natural Digital progression for Motic into Virtual slide making market
2. Offer “single-source” complete and easy integrated with VM hardware and software
3. 4. Package Applications by combining VM Digital slide with Motic Net
5. Highest Resolution Sony CCD
6. Different scanning methods; ROI slide for remote consultation
7. Value-Alternative to customer
Motic: Value-Based alternative to easy and Motic: Value-Based alternative to easy and efficient digital slide creation and integration!efficient digital slide creation and integration!