Group 3 BSPharmacy 4A

MOTHBALLSOther Names:

White tar Naphthalene Naphthalin NaphtheneChemical Composition:

Mechanism of Toxicity:

It can cause gastrointestinal upset, and both may cause CNS stimulation. In addition, naphthalene may produce hemolysis, especially in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency.Uses:

In addition to repelling or killing insects such as moths, mothballs have been suggested for use as a stovepipe cleaner, a snake repellent, and to keep away mice or other pests.Toxic Effects: Acute ingestion usually causes prompt nausea and vomiting. Both compounds are volatile, and inhalation of vapors may cause eye, nose, and throat irritation.Naphthalene. Agitation, lethargy, and seizures may occur with naphthalene ingestion. Acute hemolysis may occur, especially in patients with G6PD deficiency. Chronic inhalation has also caused hemolytic anemia.

Antidote: There is no specific antidote

DecontaminationPrehospital. Administer activated charcoal if available. Do not inducevomiting, because of the risk of lethargy and seizures. Do not administer milk, fats, or oils, which may enhance absorption.

Hospital. Administer activated charcoal. Gastric emptying is not necessary if activated charcoal can be given promptly.