Molecular genetics and immunoanalysis in blood coagulation
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c‘omp. Biochem. Ph,~io/. Vol. 93A, No. 4. pp. 919-921, 1989 Maxwell Pergamon Macmillan pk. Printed in Great Britain BOOK REVIEWS Neurobiology of Invertebrates-Edited by J. SALANKI and K. S. R~ZSA. 769 pp. 1988. Akademiai Kiado, Budapest. f46.75. This is the sixth volume on the neurobiology of inverte- brates. It contains 60 papers arranged into topics: physiol- ogy and pharmacology of identified cells and pathways: peptidergic mechanisms; modulation, integration and learn- ing: ionic channels and intracellular mechanisms. The differ- ent invertebrate species offer special and often unique experimental advantages over mammals. Invertebrates allow an unambiguous investigation of the basic principles of neurobiology and so have revealed new facts and ideas. The present volume provides an excellent account of the research into the brains of animals that had solved transmis- sion, learning and living, 300 million years before the mammals appeared on earth. Membrane Proteins: Structure, Function and Assembly- Edited by J. RYDSTROM. 248 pp. 1988. Cambridge University Press, Cambridge. $47.50. This set of 29 concise reviews has the articles grouped under the headings: receptors. channels and transport proteins; electron transport proteins; ATP synthetases and transport ATPases; reaction centres, light-harvesting proteins and photo-synthetic membranes: lipid protein interactions and membrane fusion; biosynthesis and assembly of membrane proteins. The primary structure of more than 100 membrane proteins has now been determined. Preparations of two- dimensional crystals of membrane proteins. including com- plex multi-subunit enzymes, i.e. cytochrome-c oxidase and uniquinol-cytochrome-c reductase. have provided informa- tion about their tertiary and quarternary structure and membrane topology. The photosynthetic reaction centre of Rhodopseudomonas riridis has been analysed at a resolu- tion better than 3 A. There is better understanding of the mechanisms of protein synthesis in the cytosol, mitochon- dria and chloroplast; the genes regulating protein synthesis; and the processing and assembly within and across the membranes. These topics are fully discussed in the present volume. Cbolecystokinin Antagonists-Edited by R. Y. WANG and R. SCHOENFELD. 354 pp. 1988. Alan R. Liss. New York. $74. CCK, a 33 amino acid peptide. is now implicated in satiety. respiration. thermoregulation, sedation, analgesia, CNS neurotransmission, schizophrenia and many other behav- ioral disorders. CCK is found in neurons in the cerebral cortex as well as coexisting with dopamine-containing neu- rons. The classical CCK antagonists have been cyclic nucle- otides such as dibutyryl cyclic GMP. amino acid derivatives such as benzotrip and proglumide and C-terminal peptide fragments such as CCK (27-32)-NC?. A new generation of more powerful antagonists have been developed, such as lorglumide; the benziodiazepine L-364-718; and the hydrid between it and lorglumide. Several CCK-derived peptides and pseudopeptides have been synthesized and have pro- vided potent CCK receptor antagonists. They have shown that the CCK receptors in the CNS and periphery are heterogeneous. The development of antagonists to this important polypeptide has led to an increased understand- ing of the role of CCK and is well described in this multi-authored book. Fibroneetirt-Edited by D. F. MOSHER. 474 pp. 1989. Aca- demic Press, San Diego. $95. Fibronectins (F) are adhesive glycoproteins of molecular weight 200,000-250,000, found on cell membrane surfaces, in plasma, in connective tissue matrices and in fibrin clots. F is involved in cell adhesion, the cellular spreading of fibroblasts. and in the developing embryo for mesodermal migration during gastrulation. The chapters in this volume deal with: the primary structure of F; physical properties of F: F domains and receptors; F and pericellular matrix; F-cytoskeleton relationship; assembly of F in cultured human fibroblasts cells; F in embryogenesis: F in wound healing; F and malignant transformation; F and platelet adhesive functions; F interactions with pathogenic microor- ganisms; F in the kidney; F in rheumatic disease; F and the lung; F and phagocytic function and lung vascular integrity; and preparation of F for therapeutic administration. It is possible that F could play a part in controlling cell division and tissue integrity. Horizons of Biochemical Engineering-Edited by SHUICHI AIBA. 374 pp. 1988. Oxford Science Publication, Oxford. $98. Biochemical engineering has made and is making consider- able advances, many of which are described in this book. Some of the topics are: what microbiologists can learn from the chemical engineer; roots and blossom of biochemical engineering; microbial physiology and biotechnology; mi- crobial growth and product formation; flow bioreactors; immobilized cells; recombinant microbes; DNA technology; enhancement ofenzyme thermostability; longevity of antibi- otic synthetase; from petroleum to muscone; L-phenylala- nine production; production of B thuringiensis insecticides; computer control of fermentation; high density cell cultiva- tion; slurry fermentation systems; simulated moving bed chromatography; waste water treatment; and biogeochemi- cal processes. Many of the developments have sprung from the work and enthusiasm of Professor Aiba and this volume is an excellent tribute to him. Molecular Genetics and lmmunoanalysis in Blood Coagula- tion-by J. C. GIDDINGS. 304 pp. 1988. Ellis Horwood/VCH, Chichester, UK. $126. There is a delicate balance in keeping the blood liquid and bringing about blood coagulation. Too much of one leads to blood loss, too much of the other leads to thrombosis. Haemostasis involves many reactions with their checks and balances. The chapters in this book deal with: general principles of haemostasis; nature of the proco- agulant proteins; the contact factors (prekallikrein, kinino- gen, Factor XII, Factor XI); Vitamin K dependent procoagulant factors (Factor II. Factor VII, Factor X, Factor IX); variants of specific factors and their deficiencies; fibrinogen; factor VIII; naturally occurring inhibitors of coagulation; the fibrinolytic mechanism; laboratory meth- ods-for immunoanalysis-of blood proteins; and ladoratory methods for blood DNA analysis. The book also discusses carrier status, fetal abnormalities and atypical variant disorders. 919
Transcript of Molecular genetics and immunoanalysis in blood coagulation
c‘omp. Biochem. Ph,~io/. Vol. 93A, No. 4. pp. 919-921, 1989 Maxwell Pergamon Macmillan pk. Printed in Great Britain
BOOK REVIEWS
Neurobiology of Invertebrates-Edited by J. SALANKI and K. S. R~ZSA. 769 pp. 1988. Akademiai Kiado, Budapest. f46.75.
This is the sixth volume on the neurobiology of inverte- brates. It contains 60 papers arranged into topics: physiol- ogy and pharmacology of identified cells and pathways: peptidergic mechanisms; modulation, integration and learn- ing: ionic channels and intracellular mechanisms. The differ- ent invertebrate species offer special and often unique experimental advantages over mammals. Invertebrates allow an unambiguous investigation of the basic principles of neurobiology and so have revealed new facts and ideas. The present volume provides an excellent account of the research into the brains of animals that had solved transmis- sion, learning and living, 300 million years before the mammals appeared on earth.
Membrane Proteins: Structure, Function and Assembly- Edited by J. RYDSTROM. 248 pp. 1988. Cambridge University Press, Cambridge. $47.50.
This set of 29 concise reviews has the articles grouped under the headings: receptors. channels and transport proteins; electron transport proteins; ATP synthetases and transport ATPases; reaction centres, light-harvesting proteins and photo-synthetic membranes: lipid protein interactions and membrane fusion; biosynthesis and assembly of membrane proteins. The primary structure of more than 100 membrane proteins has now been determined. Preparations of two- dimensional crystals of membrane proteins. including com- plex multi-subunit enzymes, i.e. cytochrome-c oxidase and uniquinol-cytochrome-c reductase. have provided informa- tion about their tertiary and quarternary structure and membrane topology. The photosynthetic reaction centre of Rhodopseudomonas riridis has been analysed at a resolu- tion better than 3 A. There is better understanding of the mechanisms of protein synthesis in the cytosol, mitochon- dria and chloroplast; the genes regulating protein synthesis; and the processing and assembly within and across the membranes. These topics are fully discussed in the present volume.
Cbolecystokinin Antagonists-Edited by R. Y. WANG and R. SCHOENFELD. 354 pp. 1988. Alan R. Liss. New York. $74.
CCK, a 33 amino acid peptide. is now implicated in satiety. respiration. thermoregulation, sedation, analgesia, CNS neurotransmission, schizophrenia and many other behav- ioral disorders. CCK is found in neurons in the cerebral cortex as well as coexisting with dopamine-containing neu- rons. The classical CCK antagonists have been cyclic nucle- otides such as dibutyryl cyclic GMP. amino acid derivatives such as benzotrip and proglumide and C-terminal peptide fragments such as CCK (27-32)-NC?. A new generation of more powerful antagonists have been developed, such as lorglumide; the benziodiazepine L-364-718; and the hydrid between it and lorglumide. Several CCK-derived peptides and pseudopeptides have been synthesized and have pro- vided potent CCK receptor antagonists. They have shown that the CCK receptors in the CNS and periphery are heterogeneous. The development of antagonists to this important polypeptide has led to an increased understand- ing of the role of CCK and is well described in this multi-authored book.
Fibroneetirt-Edited by D. F. MOSHER. 474 pp. 1989. Aca- demic Press, San Diego. $95.
Fibronectins (F) are adhesive glycoproteins of molecular weight 200,000-250,000, found on cell membrane surfaces, in plasma, in connective tissue matrices and in fibrin clots. F is involved in cell adhesion, the cellular spreading of fibroblasts. and in the developing embryo for mesodermal migration during gastrulation. The chapters in this volume deal with: the primary structure of F; physical properties of F: F domains and receptors; F and pericellular matrix; F-cytoskeleton relationship; assembly of F in cultured human fibroblasts cells; F in embryogenesis: F in wound healing; F and malignant transformation; F and platelet adhesive functions; F interactions with pathogenic microor- ganisms; F in the kidney; F in rheumatic disease; F and the lung; F and phagocytic function and lung vascular integrity; and preparation of F for therapeutic administration. It is possible that F could play a part in controlling cell division and tissue integrity.
Horizons of Biochemical Engineering-Edited by SHUICHI AIBA. 374 pp. 1988. Oxford Science Publication, Oxford. $98.
Biochemical engineering has made and is making consider- able advances, many of which are described in this book. Some of the topics are: what microbiologists can learn from the chemical engineer; roots and blossom of biochemical engineering; microbial physiology and biotechnology; mi- crobial growth and product formation; flow bioreactors; immobilized cells; recombinant microbes; DNA technology; enhancement ofenzyme thermostability; longevity of antibi- otic synthetase; from petroleum to muscone; L-phenylala- nine production; production of B thuringiensis insecticides; computer control of fermentation; high density cell cultiva- tion; slurry fermentation systems; simulated moving bed chromatography; waste water treatment; and biogeochemi- cal processes. Many of the developments have sprung from the work and enthusiasm of Professor Aiba and this volume is an excellent tribute to him.
Molecular Genetics and lmmunoanalysis in Blood Coagula- tion-by J. C. GIDDINGS. 304 pp. 1988. Ellis Horwood/VCH, Chichester, UK. $126.
There is a delicate balance in keeping the blood liquid and bringing about blood coagulation. Too much of one leads to blood loss, too much of the other leads to thrombosis. Haemostasis involves many reactions with their checks and balances. The chapters in this book deal with: general principles of haemostasis; nature of the proco- agulant proteins; the contact factors (prekallikrein, kinino- gen, Factor XII, Factor XI); Vitamin K dependent procoagulant factors (Factor II. Factor VII, Factor X, Factor IX); variants of specific factors and their deficiencies; fibrinogen; factor VIII; naturally occurring inhibitors of coagulation; the fibrinolytic mechanism; laboratory meth- ods-for immunoanalysis-of blood proteins; and ladoratory methods for blood DNA analysis. The book also discusses carrier status, fetal abnormalities and atypical variant disorders.
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