Molecular Genetics

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Molecular Genetics Understanding the Role of Molecules in Inheritance Tuesday, March 9, 2010

Transcript of Molecular Genetics

Page 1: Molecular Genetics

Molecular GeneticsUnderstanding the Role of Molecules in Inheritance

Tuesday, March 9, 2010

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Master Objectives:

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Master Objectives:

3.3.B.b Recognize that DNA codes for proteins, which are expressed as the heritable characteristics of an organism. (DOK: 1)

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Master Objectives:

3.3.B.b Recognize that DNA codes for proteins, which are expressed as the heritable characteristics of an organism. (DOK: 1)

3.3.B.e Identify possible external causes (e.g., heat, radiation, certain chemicals) and effects of DNA mutations (e.g., altered proteins which may affect chemical reactions and structural development). (DOK: 2)

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DNA provides the CODE

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DNA provides the CODE The sequence of nitrogen bases

in DNA code for the building of protein

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DNA provides the CODE The sequence of nitrogen bases

in DNA code for the building of protein

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DNA provides the CODE The sequence of nitrogen bases

in DNA code for the building of protein

The code (genes) are like a blueprint for constructing enzymes and cell parts

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Each strand of DNA contains many genes which each code for a

different protein productTuesday, March 9, 2010

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Each strand of DNA contains many genes which each code for a

different protein productTuesday, March 9, 2010

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Protein is made by linking AMINO ACIDS together

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Protein is made by linking AMINO ACIDS together

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Every 3 bases in DNA codes for a specific amino acid

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Every 3 bases in DNA codes for a specific amino acid

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The sequence of amino acids gives the protein its properties

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The sequence of amino acids gives the protein its properties

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Structural proteins and enzymes are responsible for ALL of our inherited characteristics

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Examples:

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Examples:

antibodies

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Examples:

antibodies

keratin

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Examples:

antibodies

keratin

hemoglobin

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Examples:

antibodies

keratin

hemoglobin actin and myosin

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Examples:

antibodies

keratin

hemoglobin actin and myosin

pepsin and trypsin

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The Big Picture

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The Big PictureCe

ntra

l Dog

ma

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The Big PictureCe

ntra

l Dog

ma

Prot

ein

Synt

hesi

s

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The Big PictureCe

ntra

l Dog

ma

Prot

ein

Synt

hesi

s

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Mutations are changes in the DNA that alter protein synthesis.

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All mutation requires is a change in 1 base pair...

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All mutation requires is a change in 1 base pair...

Chemicals

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All mutation requires is a change in 1 base pair...

Chemicals

UV RadiationTuesday, March 9, 2010

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All mutation requires is a change in 1 base pair...

Chemicals

UV Radiation

Nuclear Radiation

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All mutation requires is a change in 1 base pair...

Chemicals

UV Radiation

Nuclear RadiationMistakes by the Cell

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All mutation requires is a change in 1 base pair...

Chemicals

UV Radiation

Nuclear RadiationMistakes by the Cell

Carcinogens

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"DNA makes RNA and RNA makes proteins and proteins make us."

~Francis Crick

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