Modernising Medical Microbiology Annual Conference...

ModernisingMedicalMicrobiology

AnnualConference2018

Monday12thMarch2018StCatherine’sCollege,UniversityofOxford

MMMAnnualConferenceStCatherine’sCollege,TheBernardSunleyBuilding,ManorRoad,Oxford,OX13UJTelephone:+44(0)1865271700http://www.stcatz.ox.ac.ukMonday12thMarch2018

http://modmedmicro.nsms.ox.ac.uk/@ModMedMicro

Hostedby:Prof.DerrickCrookNDM,MicrobiologyResearchUniversityofOxfordLevel7JohnRadcliffeHospitalOxfordOX39DU

StCatherine’sCollege

OxfordDirections,TransportandParking

TheconferencewillbelocatedattheStCatherine’sCollege,TheBernardSunleyBuilding,Oxford:http://www.stcatz.ox.ac.uk/Oxfordisabout60miles(90km)northwestofLondonandhasexcellentroadandnationalraillinks.RegularcoachservicesconnectOxfordwiththecapitalandalsowithHeathrow,GatwickandLutonairports.PleasebeawarethereislittlepublicparkingavailableinthecentreofOxfordandStCatherine’sCollegehasverylimitedparking.WeadviseusingthePark&Rideservices.

FromLondonairportsLondonHeathrowandGatwickairportsarelinkedtoOxfordbyTheAirlinecoachservice,whichoperatesadirectfrequentservicetwenty-fourhoursaday(tel:+44(0)1865785400).LondonStanstedairportislinkedtoOxfordbytheNationalExpress757coachservice,runningeverytwohours(tel:+44(0)8705747777).Anumberofcompanies,includingOxicarsandCCBCars,offerpre-bookableairporttransfers.Details:

• LondonHeathrow;theOxfordBusCompanyAirlineservicecoachgoesdirectlytoOxford.• LondonGatwick;theOxfordBusCompanyAirlineservicecoachgoesdirectlytoOxford.• LondonStansted;thereareinfrequentdirectcoachesormorefrequentlinksviaacoachto

HeathroworLondon.• Luton;youmayneedtotakeacoachtoHeathroworLondontojoinoneoftheother

services.• BirminghamInternationalAirport;therearefrequenttrainsfromheretoOxford(seeRail

TimetableInformation)

BytrainAdirectserviceoperatesbetweenOxfordandLondonPaddington/LondonMarylebone(approximatelyevery30minutes),andbetweenOxfordandBirminghamNewStreetviaBanburyandCoventry.OtherservicesoperatefromthenorthviaBirminghamNewStreet;fromtheSouthviaReading;andfromthewestviaDidcotorReading.ForinformationcontactNationalRailEnquiries(tel:+44(0)8457484950).SeeRailTimetableInformationfordetailsoftrainstoOxfordandtopurchasetraintickets.

BycoachFrequent24-hourdirectservicesconnectOxfordwithLondon(peaktimesevery10-20minutes).TheOxfordX90serviceincludesVictoriaCoachStation,GrosvenorGardens,MarbleArch,BakerStreet/GloucesterPlaceandHillingdon(tel:+44(0)1865785400).TheOxfordTubeserviceincludesGrosvenorGardens,MarbleArch,NottingHillGate,Shepherd'sBush,andHillingdon(tel:+44(0)1865772250).Forinformationoncoachestoothermajorcitiesand

airportscontactNationalExpress(tel:+44(0)8717818181).CoachesarriveatGloucesterGreenCoachStationinthecitycentre.

• OxfordBusCompanyX90serviceortheOxfordTubecoachtoOxford.• SeetheNationalExpresswebsitefordetailsofcoachesfromothermajorcities.

Park&RideOxford'sParkandRideservice(operatedbytheOxfordBusCompany)enablesvisitorstoleavetheircarsatlocationsclosetothering-roadandtravelintothecitycentreonafrequentbusservice.ManyOxfordstreetsarenowclosedtotrafficandparkingisseverelylimited.VisitorsareencouragedtousetheParkandRidebusserviceswhichoperatebetweenthecitycentreandparkingareasontheoutskirtsatPearTree,WoodstockRoad(north);WaterEaton(north);Seacourt,BotleyRoad(west);Redbridge,AbingdonRoad(south);andThornhill,LondonRoad(east).ForalocationmapofthefivecarparksinOxfordandroutes,pleasevisitthePark&Ridewebsitehttp://www.parkandride.net

TaxisTaxiranksarelocatedatOxfordRailwayStation,GloucesterGreenCoachStationandStGiles'inthecitycentre.ABCRadioCars: 01865242424001Taxis: 01865240000EagleTaxi:07958437250A2BOxfordTaxi: 01865773333RoyalCars: 01865777333

OxfordCars: 01865406070OxfordCityCars:01865703030EliteCars: 01865249973StarTaxi: 01865986264A1Taxis: 01865248000TaxisarereadilyavailablefrombothOxfordTrainStationandGloucesterGreenCoachStationandthefaretoStCatherine’sshouldbeapproximately£7.00.

Onfoot

StCatherine'sisontheedgeoftheCityCentreandwerecommendthatvisitorsarrivingatthebusortrainstationtakeataxitotheCollege,especiallyiftheyarebringingluggage.WalkingfromtheCityCentretoStCatherine'swilltakebetween15and20minutesorfromthetrainstationaround25-30minutes.

Bybike

StCatherine'shasampleparkingforbicyclesandthebikeshedisalistedbuilding.CyclingisprobablythebestwaytogetaroundcentralOxford.

Bicyclehire

Bicyclehireisavailableatthetrainstation(Bromptonbikeshttp://www.bromptonbikehire.com/docks/2624-oxford)andatdockingstationsthroughoutthecityandUniversity(Oxonbikeshttp://www.oxonbikes.co.uk/).Ifyouwishtousethisservice,werecommendregisteringinadvance.

DocklessBikeServices:

PonyBikes:http://getapony.com/

OfoBikes:http://www.ofo.com/Obike:https://www.o.bike/#page1

GeneralInformationAccessibilityStCatherine'sCollegeisamoderncollegeandmostofitsbuildingsareaccessibletowheelchairusers.However,ifyouhaveanyspecialrequirementsfortheconference,[email protected]

ConferenceBadgesPleasewearyournamebadgeatalltimestopromotenetworkingandassiststaffinidentifyingyou.InternetAccessWifiaccessisfreelyavailable,eitherthroughEduroam(whereapplicable)orthecloud.DemosandPhotographsWewillberunningsomedemonstrationsinthefoyer.Pleasecheckouttheentriesofourphotographycompetitionaswell!ConferenceMealsCoffee,teaandpastrieswillbeavailablefrom8.20am.Coffeeandteawillalsobeservedmid-morningandagainmid-afternoon.A3-coursemealwillbeservedatlunchtime.Specialdiets,ifrequested,havebeencateredfor.Pleasemakeyourselfknowntoamemberofthecateringteaminthehall.PleasecontactAliifthereareanyissues.EveningDrinksReceptionTheconferencewillbeimmediatelyfollowedbyaneveningdrinksreceptionandthenwewillberelocatingtotheKingsArms,oneofOxford’sbestknownpubs.Pleasestayandsocialisewithus!Twitterandonlinequestions@ModMedMicrowillbetweetinganylastminutenoticesonMondaymorningsopleasefollowusbyclickingherehttps://twitter.com/ModMedMicroDuringtheconference,pleasetweetanythoughtsorusefulinformation,likepapersorwebsites,usingthe#MMM2018hashtag(itisprintedatthetoprightoftheprogramme).Alsoifduringatalkyouhaveaquestionbutdon’twanttoaskitinperson,pleasetweetitusing#MMM2018aswewillhavesomeonemonitoringthehashtagwhowillpassalonganyquestionstotheChairofthesession.

SocialMediaPolicyWeencouragesharingofquotes,commentsandimagesintheinterestsofopen,accessiblescience.However,toenableustopresentunpublisheddataweaskyoupleaseshareresponsiblyandrespectconfidentialinformation.Specifically:

• Speakersshouldbeawarethatweencouragethecontentoftheirtalktobediscussedonsocialmedia,toreachwideraudiences.@modmedmicroandassociatedscientistswillbepromotingrelevantcontent.

• Ifspeakerspreferthecontentoftheirpresentationnottobeshared,duetounpublisheddataorsensitiveinformation,pleasemakethisclearonatitleslideorbyannouncement.Delegatesareaskedtorespecttheirwishes.

• Bydefault,pleasedonotshareimagesofconferenceslides.Ifthespeakerishappyforslidestobetweetedtoreachwideraudiences,pleasemakethisclearonatitleslideorbyannouncement

• Ifimagesofslidescontainingpublisheddataareshared,pleaseensurethespeaker’ssurnameortwitterhandleisacknowledgedinthepost.

• Weencouragespeakerstoputtheirsocialmediaprofiles/Twitterhandlesontheirtitleslideiftheywishtoparticipateinthelargersocialmediadiscussion

• Allspeakerswillbemadeawareofthispolicyandwillhavetherighttorequesthoworwhethertheirpresentationisdisseminatedinsocialmediaasabove.

SustainabilityandGreenImpact

TheModernisingMedicalMicrobiologyOxfordGroupisamemberoftheUniversityofOxfordGreenImpactSchemewww.green-impact.org.ukandiscommittedtoimprovingourenvironmentalimpact,inkeepingwiththeUniversityofOxfordEnvironmentalSustainabilityPolicy.Our2018conferencebrochurewillbeelectronic,withpapercopiesonrequestonly,saving4,400sheetsofA4printingandover44,000litresofwaterinproduction.Wehaveoutlinedanumberofeasytraveloptionswhichpromotesustainability.Wewouldalsobegratefulifyoucouldmakesuretoreturnyourconferencebadgeandholderattheendofthedaysotheycanbereusedinsubsequentyears.Ifyoudorequireapapercopyoftheconferencebrochure,[email protected].

MMMconferenceMonday12March2018

Morningbreakfast,registrationandwelcome08:20-09:20 Breakfastreception,networkingandregistration

Coffee,pastries,Wifi,demosandluggagestorageavailable09:20-09:30 Welcomeandopeningaddress

DerrickCrookSession1:OneyearafterthePHETBroll-out:lessonsonimplementationandresearchadvances

Chair:PhilipFowler09:30-09:50 Controllingartefactualvariationinreportedinter-samplerelatednessduringclinicaluseofaM.tuberculosis

sequencingpipelineDavidWyllie

09:50-10:10 TowardsusingtheCRyPTICplateforM.tuberculosisdrugsusceptibilitytestingClaraGrazian

10:10-10:30 TheCRyPTICM.tuberculosisbioinformaticspipelineMartinHunt

10:30-10:50 10%there:predictionoffirst-linetuberculosisdrugsusceptibilityprofilesfrom10,000genomesTimWalker

10:50-11:10 BeyondCOMPASSJeremySwann/FanYang-Turner

11:10-11:50 MorningcoffeebreakSession2:Andnowforsomethingcompletelydifferent

Chair:SarahWalker11:50-12:20 C.aurisoutbreak

DavidEyre/KatieJeffery12:20-12:50 The"AntibioticReviewKit”

MartinLlewelyn12:50-14:00 Lunch

Session3:Upfromthedeep:theroleofwaterreservoirs,plumbingandsewageChair:TimPeto

14:00-14:20 TRACEcardiothoracicDerrickCrook

14:20-14:40 WhatisdownthesinksattheJohnRadcliffehospital?KevinChau

14:40-15:00 TheroleoftheenvironmentinsustainedKPCtransmissionattheUniversityofVirginiaMedicalCenterAmyMathers

15:00-15:20 REHAB.Theenvironmentalresistome:confluenceofHumanandAnimalBiotainantibioticresistancespread.NicoleStoesser

15:20-16:00 AfternooncoffeebreakSession4:Thefutureisbright,thefutureisNanopore?

Chair:DerrickCrook16:00-16:20 DirectfromsamplesequencingforM.tuberculosis

KateDingle/SophieGeorge16:20-16:40 PreparingfortheNanoporedeluge

NickSanderson16:40-17:00 Flu&viraldetection

StevePullan/YifeiXu17:00-17:25 Panel:So,isthefutureNanopore…?17:25-17:30 Closingremarks17:30-18:00 Drinksreception

18:30 Pub(KingsArms,40HolywellSt,OX13SP.Pubonthewaytotrain/busstation,10minwalk)*20minslots:10minstalk+10minsdiscussion.30minslots:20minstalk+10minsdiscussion

#MMM2018@ModMedMicro

FundersandPartners

And a big thank you to all of our collaborators.

WhileinOxforddon’tmissthemajorsoloexhibition“BioArtandBacteria”byModernisingMedicalMicrobiology’sartistinresidenceAnnaDumitriu.TheexhibitionisdailyTuesdaytoSunday12-5pmuntil18thMarch2018attheMuseumoftheHistoryofScience,BroadStreetOxford.“BioArtandBacteria”featurescollaborationswithmanyModernisingMedicalMicrobiologyresearchersandcollaborators(includingProfessorJohnPaul,DrNicolaFawcett,KevinCole,TimWalkerandJamesPrice)andexploresantibioticresistance;wholegenomesequencing,syntheticbiology,CRISPRandinfectiousdiseases,includingcontemporaryartworksmadeusingbacteriaandDNA.DumitriuhasrecentlybeenawardedfundingfromArtsCouncilEnglandtocontinueherworkwithModernisingMedicalMicrobiologyandtodevelopanewresidencywiththeNationalCollectionofTypeCulturesatPublicHealthEngland.FollowingitsruninOxford“BioArtandBacteria”willtourtotheEstherKleinGalleryatPhiladelphiaScienceCenter(OctoberandNovember2018)andEdenProjectinCornwall(Spring2019).Alsonottobemissedis“Superbugs:TheFightforourLives”attheScienceMuseuminLondonwhichrunsthroughout2018andcontainsandinstallationofPetridishesofsuperbugswhichhavebeenmadesafeforexhibitionbyDumitriuincollaborationwithProfessorJohnPaul,ProfessorMartinLlewellyn,KevinCole,DrDaireCantillion,DrNicolaFawcettandDrJamesPrice.Seemoreatwww.annadumitriu.co.uk

StCatherine'sCollege

Railwaystation

KingsArmspub

NearestOxfordTube/X90Busstop

Accommodation

Unfortunately,wearenotabletoprovideaccommodationforconferenceattendeesonthisoccasion.Ifyourequireaccommodation,pleaseconsultthetablebelowforlocalestablishments:Hotels<1milefromStCatherine’sCollege

Contact Cost/singlepernightBookedDirect(startingfrom)

distancefromStCatherine’sCollege

Park&RideBusroute

GeorgeOxfordHotel 01865727400https://www.georgeoxfordhotel.com/

£78.00

15minwalk(0.8miles)

AllP&Rsclosetocentralbusstation

MercureOxfordEastgateHotel 01865 248332http://www.mercure-oxford-eastgate-hotel

£128.00

10minwalk(0.4miles)

AllP&Rsclosetocentralbusstation

UniversityRoomsVariousroomsavailableinOxfordColleges

https://www.universityrooms.com/ £35.00 Scatteredaroundthecitty

Hotels>1milefromStCatherine’sCollege

RoyalOxfordHotel 01865248432http://www.royaloxfordhotel.co.uk/

£124.00

22minwalk(1.1miles)

NeartheTrainStationSeacourtP&R400

RewleyHouse 01865270362https://www.conted.ox.ac.uk/facilities/

£73.00 22minwalk(1.1mile)

WaterEatonP&R500orPearTree300

CotswoldLodgeClassicHotel 01865512121http://www.cotswoldlodgehotel.co.uk/

£97.00 22minwalk(1.1mile)

WaterEatonP&R500

BestWestern 08443876133https://www.best-western-linton-lodge-hotel

£52.00 25minwalk(1.3miles)

WaterEatonP&R500

StMargaret'sHotel 01865433864http://www.thestmargaretshotel.co.uk/

£140.00 26minwalk(1.4miles)

WaterEatonP&R500

Parklands 01865554374http://www.parklandsoxford.co.uk/location/

£135.00(throughBooking.com)

28minwalk(1.4miles)

WaterEatonP&R500

TheGalaxie 01865515688http://www.galaxie.co.uk/

£84.00 35minwalk(1.8miles)orbus

WaterEatonP&R500

Hotels>1milefromStCatherine’sCollege

LonsdaleGuestHouse 01865308833http://www.theoxfordguesthouse.co.uk/


WaterEatonP&R500

MarlboroughHouseHotel 01865311321http://www.marlbhouse.co.uk/en-gb/home.aspx


PearTreeP&R300

CotswoldHouse 01865310558http://www.cotswoldhouse.co.uk/index.php


WaterEatonP&R500

RemontOxfordHotel 01865311020http://www.remont-oxford.co.uk/home


WaterEatonP&R500

Jury’sInn 01865489988https://www.jurysinns.com/hotels/oxford

£93.00 29minbybus

PearTreeP&R300

AlternativeAccommodationAirBnB:https://www.airbnb.co.uk/Allprices,contactdetailsandotherinformationwerecorrectat2ndFebruary2018.

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