ANRSTHE ANRS IN BRIEF

The French Research Agency ANRS (France REcherche

Nord & sud Sida-hiv Hépatites) was created by the

government in 1988, against a background of urgent

scientific and public health need.

It works with researchers from the Global North and

South, from all disciplines, and all affiliations, on

scientific issues that have been identified as priorities

and where results are likely to contribute:

– to a better understanding of biological mechanisms

(basic research)

– to the development of new diagnostic and therapeutic

tools and strategies (clinical research)

– to the analysis of population-level issues (human and

social sciences and epidemiological research)

– to the development and assessment of prevention

strategies (vaccine research and public health research).

The ANRS funds research projects after they have been

assessed by committees of international experts.

It supports projects from conception through to

completion and disseminates their results for the wider

benefit of communities.

Since 2012, it has been an autonomous agency within

Inserm.

– To find out more, see our annual review

at wwww.anrs.fr

– Sign up to our Newsletter

– Follow us on Twitter @agence_ANRS

2018 IN FIGURES2018 IN FIGURES

BudgeT €45,6 million in appropriations

92% of the budget is dedicated to research funding

€11 million in staff funding, equating to 243 PhD and

postdoctoral researchers, clinical, fundamental, and social

sciences research monitors, and methodology and management

center (CMG) staff

STAFF 55 people at the ANRS head office

ANRS AS A STudy SpoNSoR 32 ANRS-sponsored studies involving human participants are

currently ongoing, including 8 clinical trials, 14 cohort studies,

7 pathophysiological studies and related studies, the majority of

them multicenter

Almost 35,000 patients are enrolled in these studies,

including 21,300 in the ANRS CO22 HEPATHER cohort

1 global network of over 250 hospital departments,

40 of which account for 70% of activities

6 methodology and management centers

1 central biobank to store samples: 1,400,000 specimens held

1 specific biobank dedicated to the ANRS CO22 HEPATHER

cohort: 900,000 specimens held

puBlicATioNS 342 scientific articles published in 2018 produced from ANRS-

funded projects

2018 cAll FoR pRojecTS 155 research projects submitted, with 80 new projects

selected

90 research grant applications submitted, with 51 selected

350 projects and grants resulting from calls for proposals were

active in 2018, including those ongoing from previous calls for

projects

Brazil

Site countries

Senegal

Côte d’Ivoire

Burkina FasoVietnam

Cambodia

Kazakhstan

Cameroon

Afrique du Sud

No-site countries

EgyptMali

GuineaSuriname

Burundi

Madagascar

DR Congo Zambia

Mozambique

UgandaTogo

ANRS AROUND THE WORLDANRS AROUND THE WORLD

Mindful of the global aspects of the international fight against HIV, since its creation ANRS has

always conducted a significant amount of research in countries in the Global South, working in

collaboration and partnership with national institutions and local teams.

This research aims to identify interventions appropriate to the public health priorities in these

countries. ANRS continues to have a significant presence in its eight research sites in countries with

limited resources (Brazil, Burkina Faso, Cambodia, Cameroon, Côte d’Ivoire, Egypt, Senegal, and

Vietnam) while developing an increasing number of multi-country projects.

AdviSoRy BoARd

presidentLouis Gautier, conseiller maître à la Cour des comptes, Paris

MembersAnne Paoletti, direction générale de la recherche et de l’innovation (DGRI), ministèrede l’Enseignement supérieur, de la recherche et de l’innovation, ParisJean-Christophe Comboroure, direction générale de la santé (DGS), ministère desSolidarités et de la Santé, ParisDominique Waag, sous-direction de l’Enseignement supérieur et de la Recherche,ministère de l’Europe et des Affaires étrangères, ParisGilles Bloch, président-directeur général de l’Inserm, ParisStéphane Emiliani, CNRS, ParisMartine Peeters, IRD, MontpellierFélix Rey, Institut Pasteur, ParisÉric Fleutelot, Expertise France, ParisMarianne L’Hénaff, Association VIHAgnès Michel, Association hépatitesSouleyman M’Boup, IRESSEF, Dakar, SénégalFrançoise Brun-Vézinet, Hôpital Bichat-Claude Bernard, ParisJean-Philippe Pageaux, CHU Saint-Eloi, Montpellier

François Dabis, directeur de l’ANRS, ParisThibault Robert, ANRS, ParisThierry Menvielle, ANRS, Paris

ScieNTiFic AdviSoRy BoARd

presidentGuido Silvestri, Emory University, Atlanta, États-Unis

vice-présidentFabien Zoulim, Hospices civils de Lyon

MembersFareed Abdullah, South African Medical Research Council (SAMRC), Prétoria, Afrique du SudGeneviève Almouzni, Institut Curie, ParisMeg Doherty, Department of HIV and Global Hepatitis Programme, OMS, Genève, SuisseDaniel Douek, NIAID/NIH, Bethesda, États-UnisMatthias Egger, Institute for Social and Preventive Medicine (ISPM), University of Bern, SuisseDiana Finzi, DAIDS/NIH, Bethesda, États-UnisArnaud Fontanet, Institut Pasteur, ParisAlter Galit, Ragon Institute of MGH, MIT and Harvard, Cambridge, États-UnisSharon Lewin, Doherty Institute, University of Melbourne, AustralieAnna Lok, University of Michigan, Ann Arbor, États-UnisVinh-Kim NGuyen, Graduate Institute of International and Development Studies,Genève, Suisse

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Rodolphe Thiebaut, ISPED, Université de Bordeaux, membre du Conseil scientifique de l’InsermRobert Thimme, University of Freiburg, AllemagneChristian Trépo, Hôpital Hôtel-Dieu, LyonStephan de Wit, Hôpital Saint-Pierre, Bruxelles, Belgique

observing membersHugues Fischer, Act Up-Paris, ParisMichelle Sizorn, SOS Hépatites, Paris

ScieNTiFic evAluATioN coMMiTTeeS

cSS11 “Hiv basic science: host-virus interactions”président: Francis Barin, CHU Bretonneau, Toursvice-président: Nicolas Chomont, Université de Montréal, Canada

cSS12 “Hepatitis basic science”président: Massimo Levrero, Centre de recherches en cancérologie de Lyon (CRCL), Lyon

cSS13 “clinical research”présidents: Alexandra Calmy, Hôpital cantonal universitaire de Genève, Suisse, et Marc Bourlière, Hôpital Saint-Joseph, Marseille

cSS14 “public health, human and social sciences”présidents: Guillaume Lachenal, Université Paris Diderot, Paris et Joseph Larmarange, Centre Population et développement (Ceped), IRD, Paris

cooRdiNATed AcTioNS

Ac 41 “virus–host interactions”president: Michaela Müller-Trutwin, Institut Pasteur, Paris

Ac 42 “Hepatitis viruses basic science”president: François-Loïc Cosset, École Normale Supérieure (ENS), Lyon

Ac 43 “Medical virology”presidents: Vincent Calvez, Hôpital de la Pitié-Salpêtrière, Paris, Stéphane Chevaliez, Hôpital Henri-Mondor, Créteil et Avelin Aghokeng, IRD, Montpellier et Centre international de recherches médicales (CIRMF) Franceville, Gabon

Ac 44 “Hiv clinical research”presidents: Olivier Lambotte, Hôpital du Kremlin-Bicêtre et Serge Eholié, CHU de Treichville,Abidjan, Côte d’Ivoire

Ac 45 “clinical research in viral hepatitis”presidents: Hélène Fontaine, Hôpital Cochin, Paris et Karine Lacombe, Hôpital Saint-Antoine, Paris

Ac 46 “public health and social sciences”presidents: Bruno Spire, Inserm, Marseille et Didier Ekouevi, Université de Lomé, Togo

Ac 47 “dynamic and control of Hiv and hepatitis epidemics”president: Dominique Costagliola, Institut Pierre Louis d’épidémiologie et de santé publique (IPLESP), Sorbonne Université, Inserm, Paris

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jANuARy 15 – MARcH 15juNe 15 – SepTeMBeR 15

ANRS is able to provide funding for research projects, early-stage research contracts,research grants, symposia, and publications in all the scientific fields that come within itspurview:– HIV/AIDS– viral hepatitis– HIV/hepatitis coinfections– related diseases or viruses if useful to the understanding of HIV/AIDS and viral hepatitis

Assessment bodies: Sector scientific committees (cSS)CSS 11 “HIV basic science: host-virus interactions”CSS 12 “hepatitis basic science”CSS 13 “Clinical research”CSS 14 “Public health, human and social sciences”

coordination groups (Ac)ACs help devise, develop, and write up research projects.They meet as often as is necessary to monitor the progress of ongoing studies, steer themif necessary, and develop new projects.The resulting projects are submitted to calls for projects and assessed by the CSS.AC 41 “Virus–host interactions”AC 42 “Hepatitis viruses basic science”AC 43 “Medical virology”AC 44 “HIV clinical research”AC 45 “Clinical research in viral hepatitis”AC 46 “Public health and social sciences”AC 47 “Dynamic and control of HIV and hepatitis epidemics”

File submission: https://apogee.anrs.frInformation and contacts: www.anrs.fr “Researcher space”

TWO CALLS FOR PROJECTS PER YEARTWO CALLS FOR PROJECTS PER YEAR

101 rue de Tolbiac — 75013 paris www.anrs.frTél. : +33 (0) 1 53946000

©ANRS, June 2019 – Document produced by the ANRS Scientific Information and Communication department. Graphic design: Isabelle Benoit. Picture: Inserm/Depardieu Michel, Latron Patrice; IRD/Wadleigh Michael; Depositphotos; Fotolia/Kateryna Kon.