Miriam Komaromy, MD Associate Director, Project ECHO Associate Professor, Internal Medicine, UNM...

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DSM-5 Approach to Substance Use Disorder (SUD) Miriam Komaromy, MD Associate Director, Project ECHO Associate Professor, Internal Medicine, UNM 10/2013

Transcript of Miriam Komaromy, MD Associate Director, Project ECHO Associate Professor, Internal Medicine, UNM...

Page 1: Miriam Komaromy, MD Associate Director, Project ECHO Associate Professor, Internal Medicine, UNM 10/2013.

DSM-5 Approach to Substance Use Disorder (SUD)

Miriam Komaromy, MDAssociate Director, Project ECHOAssociate Professor, Internal Medicine, UNM10/2013

Page 2: Miriam Komaromy, MD Associate Director, Project ECHO Associate Professor, Internal Medicine, UNM 10/2013.

DSM IV approach to SUDs was problematic

Use of the term “dependence” to mean “addiction”

Distinction between “abuse” and “dependence” as two separate entities of increasing severity

Lack of reference to Craving in the criteria

Inclusion of Legal Consequences as a criterion

Page 3: Miriam Komaromy, MD Associate Director, Project ECHO Associate Professor, Internal Medicine, UNM 10/2013.

Substance Use Disorder (SUD)(Substance-Related and Addictive Disorders)

Consolidate substance abuse with substance dependence into a single disorder called substance use disorder

Rationale: Dependence is a misunderstood term that has negative connotations when in fact it refers to normal patterns of withdrawal that can occur from the proper use of medications.

Copyright © 2013. American Psychiatric Association.

Page 4: Miriam Komaromy, MD Associate Director, Project ECHO Associate Professor, Internal Medicine, UNM 10/2013.

Medical providers and patients often confuse physical dependence with addiction

Medical providers who confuse these two may make poor medical decisions

Patients may experience guilt and anxiety because of symptoms of withdrawal or tolerance

Page 5: Miriam Komaromy, MD Associate Director, Project ECHO Associate Professor, Internal Medicine, UNM 10/2013.

Abuse vs. Dependence in DSM IV

Intended to represent less severe and severe SUD

Not always accurateSame criteria for substances that cause

physical dependence and those that don’tDSM V solution: SUD is a single category,

of graded severity

Page 6: Miriam Komaromy, MD Associate Director, Project ECHO Associate Professor, Internal Medicine, UNM 10/2013.

DSM V approach to variations in severity

Rather than using the presence or absence of dependence to indicate increased severity, DSM V uses # of criteria to indicate severity

Page 7: Miriam Komaromy, MD Associate Director, Project ECHO Associate Professor, Internal Medicine, UNM 10/2013.

DSM-IV and DSM-5 Criteria for Substance Use Disordersa One or more abuse criteria within a 12-month period and no dependence diagnosis; applicable to all substances except nicotine, for which DSM-IV abuse criteria were not given.b Three or more dependence criteria within a 12-month period.c Two or more substance use disorder criteria within a 12-month period.d Withdrawal not included for cannabis, inhalant, and hallucinogen disorders in DSM-IV. Cannabis withdrawal added in DSM-5.

Hasan, D. Am J Psychiatry. 2013;170(8):834-851

Page 8: Miriam Komaromy, MD Associate Director, Project ECHO Associate Professor, Internal Medicine, UNM 10/2013.

DSM-IV and DSM-5 Criteria for Substance Use Disordersa One or more abuse criteria within a 12-month period and no dependence diagnosis; applicable to all substances except nicotine, for which DSM-IV abuse criteria were not given.b Three or more dependence criteria within a 12-month period.c Two or more substance use disorder criteria within a 12-month period.d Withdrawal not included for cannabis, inhalant, and hallucinogen disorders in DSM-IV. Cannabis withdrawal added in DSM-5.

Hasan, D. Am J Psychiatry. 2013;170(8):834-851

Example of DSM V Mild SUD (2-3)

Page 9: Miriam Komaromy, MD Associate Director, Project ECHO Associate Professor, Internal Medicine, UNM 10/2013.

DSM-IV and DSM-5 Criteria for Substance Use Disordersa One or more abuse criteria within a 12-month period and no dependence diagnosis; applicable to all substances except nicotine, for which DSM-IV abuse criteria were not given.b Three or more dependence criteria within a 12-month period.c Two or more substance use disorder criteria within a 12-month period.d Withdrawal not included for cannabis, inhalant, and hallucinogen disorders in DSM-IV. Cannabis withdrawal added in DSM-5.

Hasan, D. Am J Psychiatry. 2013;170(8):834-851

Example of DSM V Moderate SUD (4-5)

Page 10: Miriam Komaromy, MD Associate Director, Project ECHO Associate Professor, Internal Medicine, UNM 10/2013.

DSM-IV and DSM-5 Criteria for Substance Use Disordersa One or more abuse criteria within a 12-month period and no dependence diagnosis; applicable to all substances except nicotine, for which DSM-IV abuse criteria were not given.b Three or more dependence criteria within a 12-month period.c Two or more substance use disorder criteria within a 12-month period.d Withdrawal not included for cannabis, inhalant, and hallucinogen disorders in DSM-IV. Cannabis withdrawal added in DSM-5.

Hasan, D. Am J Psychiatry. 2013;170(8):834-851

Example of DSM V Severe SUD (> 6)

Page 11: Miriam Komaromy, MD Associate Director, Project ECHO Associate Professor, Internal Medicine, UNM 10/2013.

“An important exception to making a diagnosis of DSM-5 substance use disorder with two criteria pertains to the supervised use of psychoactive substances for medical purposes, including stimulants, cocaine, opioids, nitrous oxide, sedative-hypnotic/anxiolytic drugs, and cannabis in some jurisdictions”

Hasan, D. Am J Psychiatry. 2013;170(8):834-851

For prescribed medications, the presence of tolerance and withdrawal alone do not signify a Substance Use Disorder

Page 12: Miriam Komaromy, MD Associate Director, Project ECHO Associate Professor, Internal Medicine, UNM 10/2013.

Substance Use Disorder (cont’d)

Rationale continued: Further, studies from clinical and general populations indicate DSM-IV substance abuse and dependence criteria represent a singular phenomenon but encompassing different levels of severity. Mild SUD (2-3/11 criteria) will be coded with the DSM-IV substance abuse code to reflect the intent but not reality of considering substance abuse less severe than substance dependence. Moderate (4-5/11 criteria) and severe (6+/11 criteria) SUD will be coded with DSM-IV substance dependence codes.Copyright © 2013. American Psychiatric Association.

Page 13: Miriam Komaromy, MD Associate Director, Project ECHO Associate Professor, Internal Medicine, UNM 10/2013.

Substance Use Disorder (cont’d)Removal of one of the DSM-IV abuse criteria

(legal consequences), and addition of a new criterion for SUD diagnosis (craving or strong desire or urge to use the substance)

Rationales: The legal criterion had poor clinical utility and its relevance to patients varied based on local laws and enforcement of those laws. Addition of craving as a symptom is highly validated, based on clinical trials and brain imaging data, and may hold potential as a future biomarker for the diagnosis of SUD.

Copyright © 2013. American Psychiatric Association.

Page 14: Miriam Komaromy, MD Associate Director, Project ECHO Associate Professor, Internal Medicine, UNM 10/2013.

Additional Specifiers

In early remissionIn sustained remissionOn maintenance therapyIn a controlled environmentDiagnosis should contain specific

substance, e.g. “Alprazolam use disorder’List each dx separately (no poly-

substance)

Page 15: Miriam Komaromy, MD Associate Director, Project ECHO Associate Professor, Internal Medicine, UNM 10/2013.

Other changes

Page 17: Miriam Komaromy, MD Associate Director, Project ECHO Associate Professor, Internal Medicine, UNM 10/2013.

Cannabis withdrawal added

Page 19: Miriam Komaromy, MD Associate Director, Project ECHO Associate Professor, Internal Medicine, UNM 10/2013.

Miriam Komaromy, [email protected]