Mik Black NZ Society of Oncologists 2010
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Transcript of Mik Black NZ Society of Oncologists 2010
Collaborative initiatives that are changing the face of cancer research ���
Mik Black���Department of Biochemistry���
University of Otago���
The good old days: sharing data
The good old days: sharing data
Oncomine: adding value
http://www.broadinstitute.org/cmap/
Nature Reviews Cancer, 2007: 7(1) 54-60
http://tcga.cancer.gov/
Nature (2008) vol. 455 (7216) pp. 1061-8
http://www.sanger.ac.uk/genetics/CGP/
http://www.icgc.org/
http://www.icgc.org/
http://cabig.cancer.gov/ https://cabig.nci.nih.gov/
http://cabig.cancer.gov/caBIGstory/vision/
http://cabig.cancer.gov/caBIGstory/mission/
http://cagrid.org/
BeSTGRID: Broadband-enabled Science and Technology GRID ���
http://www.bestgrid.org
BeSTGRID: Broadband-enabled Science and Technology GRID ���
http://www.bestgrid.org
Nick Jones Director, BeSTGRID Associate Director eResearch Centre for eResearch The University of Auckland [email protected]
eResearch landscape
http://www.cellml.org
http://www.geneious.com/karen
http://biomirror.org.nz
http://sakai.bestgrid.org
A few BeSTGRID activities…
+ BLAST
Coming soon…
• Large “meta-cohort” of public breast cancer samples: – 2116 patients: molecular, clinical, and treatment information
– Collaboration with Assoc Prof Lance Miller (Wake Forest), Dr Heather Cunliffe (TGen), Assoc Prof Cris Print (Auckland).
• Goal: molecular markers for personalized prediction: prognosis and response to treatment.
Putting the bits together…
Acknowledgements University of Otago Marcus Davy Thomas Allen Sarah Song Anthony Reeve Parry Guilford John McCall Tony Merriman
Translational Genomics (TGen) Heather Cunliffe
Wake Forest University Lance Miller
The University of Auckland Nick Jones Mark Gahegan Yuriy Halytskyy Cristin Print Daniel Hurley Christoff Knapp
University of Canterbury Vladimir Mencl