MidiCaps and Mini Cartridges for the biopharma- ceutical ... · for the biopharma-ceutical...

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MidiCaps ® and Mini Cartridges for the biopharma- ceutical industry

Transcript of MidiCaps and Mini Cartridges for the biopharma- ceutical ... · for the biopharma-ceutical...

Page 1: MidiCaps and Mini Cartridges for the biopharma- ceutical ... · for the biopharma-ceutical industry. About Sartorius Sartorius AG is an internationally leading process technology

MidiCaps® and Mini Cartridgesfor the biopharma-ceutical industry

Page 2: MidiCaps and Mini Cartridges for the biopharma- ceutical ... · for the biopharma-ceutical industry. About Sartorius Sartorius AG is an internationally leading process technology

About Sartorius

Sartorius AG is an internationally leadingprocess technology supplier covering the segments of biotechnology and mechatronics.The Goettingen-based company founded in1870 currently employs a good 3.750 persons.

Our Biotechnology Division serves all stepsfrom development to production in the biopharmaceutical industry, featuring specialfilters, fermenters and bioreactors, productsfor membrane chromatography and virusclearance, bags, containers and mixing systems for fluid media handling as well as an extensive service portfolio. For all processsteps and scales Sartorius offers the advantages of integrated and cost-efficientdisposable solutions to

– Avoid Cross-Contaminations,– Eliminate the need for Cleaning,– Increase Production Capacities,– Reduce Time to Market.

The mechatronics segment particularly consists of products for weighing, measurement and automation technology in laboratory and industrial applications. Sartorius key customers are from the bio- pharmaceutical, chemical and food and beverage industries and from numerousresearch and educational institutes of the public sector.

Sartorius has its own production facilities in Europe, Asia and America as well as salessubsidiaries and local commercial agencies in more than 110 countries.

Page 3: MidiCaps and Mini Cartridges for the biopharma- ceutical ... · for the biopharma-ceutical industry. About Sartorius Sartorius AG is an internationally leading process technology

FiltrationTechnologySartorius MidiCaps and Mini Cartridges areespecially used for development and clinicalproduction as well as for pilot scale applica-tions. Sartorius provides a broad range of different membrane materials as well as depthfilter materials to match the multiple applica-tion requirements of the biopharmaceuticalindustry. Featuring multiple connector styles,adaptor types and filter formats, Sartorius MidiCaps and Mini Cartridges can be easilyincorporated into any filtration process.

Final Sterilizing Grade FiltersThe Sartorius product range of Sterilizing GradeFilter elements for liquids consists of 3 differenttypes of hydrophilic membrane filters. – Featuring ultra low binding Cellulose Acetate

membranes, Sartobran P filters are typicallyused for filtration of high value pharmaceuti-cals like coagulation factors, vaccines andpreservative containing solutions.

– Sartopore 2 filters provide highest totalthroughput performance based on the highlyasymmetric PES membrane, assuring lowestfiltration costs, e. g. in media filtration.

– Sartolon filter elements are ideal for filtra-tion for a wide range of solvents and liquidscontaining solvents.

PrefiltrationBiological solutions often contain heavy loadsof particles and other contaminants which prematurely plug 0.2 µm rated and smaller sizemembrane filters. The use of Sartorius prefiltersprotects downstream Sterilizing Grade Filterseffectively and enhances significantly theirtotal throughput performance.

Sartoclean CA membrane prefilters are used for bioburden reduction in front of final mem-brane filters assuring highest product yields bylowest unspecific adsorption due the celluloseacetate membrane material. In combinationwith glass fibre fleeces Sartoclean GF prefiltersadd adsorptive power to enhance the clarifica-tion effect.

Sartopure PP 2 polypropylene depth filters arethe ideal choice for removal of hard, nondeformable particles upstream of final mem-brane filters to enhance their total throughputperformance. Featuring highly adsorptive glassfibre fleeces Sartopure GF Plus filters are theideal choice for removal of contaminants likecolloids, lipids and protein aggregates (HostCell Protein). They are used for protection ofmembrane filters, chromatography columns,crossflow systems and other downstream processing equipment to assure efficient purification steps with highest product yields.

Page 4: MidiCaps and Mini Cartridges for the biopharma- ceutical ... · for the biopharma-ceutical industry. About Sartorius Sartorius AG is an internationally leading process technology

MidiCaps®

MidiCaps® feature an innovative capsulehousing design which improves security, filter handling and ease of use. The uniquelabelling, the new valve design, the broadrange of connector styles and filter sizes arekey features of MidiCaps.

ApplicationsMidiCaps® are available for all filter materials.Therefore, MidiCaps® can be used for a broadrange of applications in biopharmaceuticalmanufacturing and form & filling operationslike:

– Sterilising Grade Filtration

– Mycoplasma Retentive Filtration

– Bioburden Reduction

– Prefiltration

– Clarification

Unique LabellingMidiCaps feature a comprehensive and easy to read out labelling on the capsulehousing including:

– Filter Type

– Order Code | Lot-no. | Piece-no.

– Pore-Size or Retention Rating

– Operating Parameters

– Flow Direction Indication

This labelling allows secure identification of each filter and assures traceability of thefilter throughout the whole process. Operatorerrors and filter mishandling as well as filtermix-ups are eliminated. Thereby MidiCaps®

contribute significantly to improve the overall safety of manufacturing processes.

Fluid ContainmentThe vent design including a double o-ringsealing and an integral hose barb for fluidcontainment avoid contamination and protect operators in an optimal way. The vent design features a defined open | closeposition to enhance ease of use.

Flexible IntegrationMidiCaps® are available with a broad range of different connector styles and with variousfilter sizes to allow for an easy integrationinto any process.

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Mini Cartridges

Mini cartridges feature the same constructionand materials as all our standard filter elements. They are designed for small scalebatch filtration in R&D, pilot scale and production. Mini cartridges are used in stainless steel housings and due to their rigidconstruction they withstand multiple in-linesteam sterilization cycles if required.

Scale-upOur Sartopore 2 & Sartobran P filter elments,for example, are made with the same membranes and materials of constructionfrom the smallest available filter elementwith 150 cm2/0.015 ft2 to 0.45 m2/5 ft2

up to filter cartridges and MaxiCaps with 1.8 m2/18ft2 filtration area. This productselection gives you the opportunity to easilyscale-up from R&D laboratory stages to pilot plant and production scale.

ISO 9000:2000 Certified QualityAll Sartorius filter elements including MidiCaps® and Mini Cartirdges are manufac-tured according to an ISO 9000:2000 certifiedQuality Management System. Our manufac-turing facilities operate in conformance with cGMP requirements in addition to theISO standard. Sartorius’ quality philosophyensures that our customers receive productsand services that meet the strictest qualityrequirements for reliable operation.

Validation GuidesOur entire range of filter elements are supplied with a quality assurance certificateto assist you in the validation of your manufacturing process. Comprehensive product specific validation packages areavailable for all Sartorius filter elements.

Process ValidationSartorius offers a wide range of validationsupport services to qualify the use of our filter products for your processes. The Sartorius validation service has a proven track record in assisting customers in validating their products and achieving regulatory approval.

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Membranefilters

Sartobran® P 523…

Sartoflour® GA|LG 518…

Sartolon® 510…

Sartopore® 2 544…

DescriptionSterilizinggrade pharma-ceutical filtercartridge forlow unspecificadsorption

ApplicationsSartobran P filters are ideally suitedfor all applications that require highest product recovery rates like:– Coagulation Factors, Albumine, IgG– Bacterial and Viral Vaccines– MAB’s– Bio-processed Pharmaceuticals– Diagnostics– Purified Protein Solutions– Biological Fluids– Solutions containing Preservatives

Construction– Protective polypropylene layer– Reinforced cellulose acetate

membrane– Reinforced cellulose acetate

membrane– Polypropylene drainage layer– Polypropylene outer cage,

core and end caps– Silicone O-rings standard –

optional EPDM, Viton

DescriptionSterilizinggrade pharma-ceutical filter cartridge with broadchemical compatibility

ApplicationsTypical applications include sterilizinggrade filtration of:– Therapeutics– Biological Fluids– Opthalmics– SVPs, LVPs– Antibiotics– WFI– Chemicals– Cleaning and sanitizing agents– Bulk pharmaceutical products– Mycoplasma removal

Construction– Protective polypropylene layer – Polyethersulfone membrane – Polyethersulfone membrane – Polypropylene drainage layer– Polypropylene outer cage,

core and end caps – Silicone O-rings standard –

optional EPDM, Viton – Silicone O-rings standard –

optional EPDM, Viton

DescriptionSterilizinggrade pharma-ceutical filter cartridgewith reinforcedNylon mem-brane for broadsolvent compatibility

ApplicationsFeaturing a unique hydrophillic nylon membrane, Sartolon filters areideally suited for e.g.sterilizing gradefiltration of:– Solvents– Antibiotics– Bulk Pharmaceutical Chemicals– LVP

Construction– Protective polypropylene layer – Reinforced Nylon membrane– Nylon membrane – Polypropylene drainage layer – Polypropylene outer cage,

core and end caps – Silicone O-rings standard –

optional EPDM, Viton

DescriptionPharmaceuticalgrade hydro-phobic PTFEmembrane filter cartridge

Applications– Sterile venting of tanks – Sterile air filtration for filling

equipment – Fermentation air filtration – Sterile filtration of gases – Bioreactor inlet and outlet streams – Sterile filtration of aggressive

media and solvents (LG)

Construction– Protective polypropylene layer– PTFE membrane filter – Polypropylene drainage layer– Polypropylene outer cage,

core and end caps – EPDM O-rings standard –

optional Viton

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Available Filtration Area Construction MidiCaps®

Pore Sizes Codes Connectors

0.65 + 0.45 µm 0.015; 0.03; 0.05; 15, 18 Mini Cartridges SS, SO, OO, FF, FO,0.45 + 0.2 µm 0.1; 0.2; 0.45 m2| 53 MidiCaps HH (only Size 7)0.45 + 0.1 µm 0.15; 0.3; 0.5; 1;

2; 5 ft2

Available Filtration Area Construction MidiCaps®

Pore Sizes Codes Connectors

0.8 + 0.45 µm 0.015; 0.03; 0.05; 15, 18 Mini Cartridges SS, SO, OO, FF, FO,0.45 + 0.2 µm 0.1; 0.2; 0.45 m2| 53 MidiCaps HH (only Size 7)0.2 + 0.1 µm 0.15; 0.3; 0.5; 1;

2; 5 ft2

Available Filtration Area Construction MidiCaps®

Pore Sizes Codes Connectors

0.45 + 0.2 µm 0.2 m2| 15, 18 Mini Cartridges SS, SO, OO, FF, FO,2 ft2 53 MidiCaps

Available Filtration Area Construction MidiCaps®

Pore Sizes Codes Connectors

0.45 µm 0.015; 0.03; 0.05; 12, 15, 18 Mini Cartridges SS, SO, OO, FF, FO,0.2 µm 0.1; 0.2 m2| 53 MidiCaps HH (only Size 7)0.1 µm 0.15; 0.3; 0.5;

1; 2 ft2

Connector Type S: 1 1“ sanitary flange

Connector Type F: 3“ sanitary flange

Connector Type O: 1“ single stepped hose barb

Connector Type H: 4“ multiple stepped hose barb

MidiCaps Connectors

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Prefilters

Sartoclean® CA 562…

Sartopure® PP2 559…

Sartopure® GF Plus 555…

Sartoclean® GF 560…

DescriptionPharmaceu-tical grademembraneprefilter cartridge

ApplicationsFeaturing ultra low binding celluloseacetate membranes, Sartoclean CA filters are typically used for membrane prefiltration of:– Plasma Fractions– Vaccines– MAB– Diagnostics– Purified Protein Solutions– Biological Fluids– Solutions containing Preservatives

Construction– Protective polypropylene layer– Reinforced cellulose acetate

membrane(s)– Polypropylene drainage layer– Polypropylene outer cage,

core and end caps– Silicone O-rings standard –

optional EPDM, Viton

DescriptionPrefilter cartridge forpharmaceuticalliquids contain-ing colloids and highbioburdens

ApplicationsIdeally suited for the biodurdenreduction as well as effective colloidand lipid removal from:– Fermentation broth– Serum– Plasma– Cell Culture Media– Colloid and Lipid containing

solutions

Construction– Protective polypropylene layer – Non-woven glass fiber material– Reinforced cellulose acetate

membrane – Reinforced cellulose acetate

membrane – Polypropylene outer cage,

core and end caps– Silicone O-rings, standard –

optional EPDM, Viton

DescriptionHighly adsorp-tive glassfiberprefilter withoutstandingtotal throughputperformance

ApplicationsSartopure GF Plus adsorptive depthfilters are the ideal choice for prefiltration and clarification of:– Cell Culture fluids after cell harvest– Fermentation broths– Serum free or serum containing

cell culture media– Serum– Highly viscous opthalmic and

LVP solutions– All media containing lipids and

colloids as contaminants

Construction– Protective polypropylene layer – Mutliple non-woven glass fibre

layers with progressively finerretention ratings

– Polypropylene drainage layer– Polypropylene outer cage,

core and endcaps – Silicone O-rings standard –

optional EPDM, Viton

DescriptionParticle removingpolypropylenedepth filtercartridge

ApplicationsTypical applications are particleremoval from various media like:– Plasma Fractions– Vaccines– MAB– Diagnostics– Purified Protein Solutions– Biological Fluids– Ophtalmics– Solutions containing Preservatives– WFI

Construction– Protective polypropylene layer – Multiple polypropylene layer

with progressively finer retention ratings

– Polypropylene drainage layer – Polypropylene outer cage,

core and end caps – Silicone O-rings, standard –

optional EPDM, Viton

Page 9: MidiCaps and Mini Cartridges for the biopharma- ceutical ... · for the biopharma-ceutical industry. About Sartorius Sartorius AG is an internationally leading process technology

Available Filtration Area Construction MidiCaps®

Pore Sizes Codes Connectors

3 + 0.8 µm 0.08; 0.16; 0.3; 15, 18 Mini Cartridges SS, SO, OO, FF, FO,0.8 + 0.65 µm 0.6 m2| 53 MidiCaps HH (only Size 7)0.45 0.8; 1.6; 3; 0.2 µm 6 ft2

Available Filtration Area Construction MidiCaps®

Pore Sizes Codes Connectors

0.8 + 0.65 µm 0.05; 0.1; 0.2; 15, 18 Mini Cartridges SS, SO, OO, FF, FO,3.0 + 0.8 µm 0.45 m2| 53 MidiCaps HH (only Size 7)

0.5; 1; 2; 5 ft2

Available Filtration Area Construction MidiCaps®

Retention Rates Codes Connectors

0.65 µm 0.05; 0.1; 0.2; 15, 18 Mini Cartridges SS, SO, OO, FF, FO,1.2 µm 0.45 m2| 53 MidiCaps HH (only Size 7)

0.5; 1; 2; 5 ft2

Available Filtration Area Construction MidiCaps®

Retention Rates Codes Connectors

0.65 µm 0.03; 0.05; 0.1; 15, 18 Mini Cartridges SS, SO, OO, FF, FO,1.2 µm 0.2; 0.45 m2| 53 MidiCaps HH (only Size 7)3 µm 0.3; 0.5; 1; 2; 5 ft2

5 µm8 µm20 µm50 µm

Adapter Type 15

Adapter Type 18

Adapter Type 12

Mini CartridgeAdapters

Page 10: MidiCaps and Mini Cartridges for the biopharma- ceutical ... · for the biopharma-ceutical industry. About Sartorius Sartorius AG is an internationally leading process technology

BioprocessingCompetenceSartorius offers the most comprehensivetechnology, product and service portfolioworldwide, which ranges from the discoveryof active ingredients to production all theway to compliance with the accompanyingregulatory steps. Technology from Sartoriusmakes production processes more reliable,accurate and predictable. Sartorius offers notonly products for individual production steps,but also technologically and economicallyoptimised solutions developed together with customers for complete upstream anddownstream processing.

Sartorius thinks in processes and thereforefocuses on the factors that are critical to success:

– Time to Market

– Regulatory Compliance

– Production Costs

– Production Capacities

Integrity Testing |Filter ManagementSystemsIntegrity TestingFilter integrity testing is more than using“stand-alone-units,” only. The market constantly calls for increasingly enhanced and faster technology in order to meet thecustomers ’ demands. These demands are thedriving force for our research and develop-ment as well as for our system engineers to develop innovative solutions. There are no limits in terms of technical feasibility.

Sartorius can offer a broad range of filterintegrity test solutions – beginning with our Sartocheck Junior series, Sartocheck 4 and the latest version Sartocheck 4 MultiUnit, our integrated built-in concept “integritywithin ”, WIT-Trolley and finally customizedfilter management systems.

Page 11: MidiCaps and Mini Cartridges for the biopharma- ceutical ... · for the biopharma-ceutical industry. About Sartorius Sartorius AG is an internationally leading process technology

Filter Management SystemThis is a new approach that not only focuseson filter integrity testing, but comprises allstages of the filter handling. The revolutionaryconcept makes the filter handling proceduresindependent of the point-of-use of the filter.After filtration has been completed, the filterhousing has to be taken from the filtrationline and brought to the filter managementsystem. The filtration line can be cleaned and sanitized before a new filter housing,which is sterile and integrity tested, can be reconnected.

Sartocheck 4Sartocheck 4 enables you to step into theworld of electronic records and electronic signatures. The system is designed to meet therequirements in GAMP guidelines in order tocomply with 21CFR Part 11. The reason for thecompliance with regard to data management,user handling and audit trails is to ensure100% tracebility. Furthermore, Sartocheck 4 is able to communicate via a standard networkconnection with an FTP server. This feature,which was requested by the industry, enablesthe data to be easily archived on a general fileserver.

Sartocheck 4 MulitUnitThe Sartocheck 4 MultiUnit has been developed to enable parallel integrity testingof multiple filters in the biopharmaceuticalindustry. The MultiUnit is an identical copyof the Sartocheck 4,without the user interfaceand the data management system. Each MultiUnit connected to a Sartocheck 4 is operated and controlled by this Sartocheck 4via a RS485 connection. Up to 4 MultiUnitscan be connected to one Sartocheck 4 allow-ing to integrity test up to 5 different filter systems in parallel including the testing capabilities of the Sartocheck 4 itself. Testingup to 5 filters in parallel allows to reduce thetime required for filter integrity testing in bio-pharmaceutical production significantlyand increases the efficiency of your production process.

WIThin ConceptThe WIThin concept allows the user tointegrity test the filter inside the machinewithout connecting an external integritytester, e.g.Sartocheck 4. This concept utilizesthe existing hardware and software platformsin order to integrity test the filter system. The control functions,as well as the mathematical algorithms, are directly integrated into the PC or PLC software.

Page 12: MidiCaps and Mini Cartridges for the biopharma- ceutical ... · for the biopharma-ceutical industry. About Sartorius Sartorius AG is an internationally leading process technology

Customer Support –FACTS® ProgramGet the FACTS® with the Fully Advanced Customer Total Support. The service philosophy of the Sartorius FACTS® programmeans added value for your business throughoptimization, validation, compliance andtraining support.

Helping you transform the complexity of costefficiency and regulatory compliance into a balanced situation is the goal of the FACTS®

program and the BioPharm-Alliance, whichhas extended our performance spectrum. The alliance with Parexel Consulting, an independent supplier and market leader inthe sector of validation and regulatory compliance, was established in 2003.

FACTS® and BioPharm-Alliance Program isdivided into four service categories:

COMPLETE – Installation|Main-tenance|RepairsBy having your equipment and systems professionally installed and serviced, you canensure that your equipment will run perfectlyat all times and deliver optimal performance.Moreover, regular maintenance increases thelife of your equipment and systems, and prevents unnecessary downtimes. As part ofour Complete program, the Sartorius serviceteam offers you the following services:– Installation and commissioning– Maintenance and service contracts– Certificates– Calibration service– Repair and corrective maintenance– Original spare parts– Hotline and technical support

Page 13: MidiCaps and Mini Cartridges for the biopharma- ceutical ... · for the biopharma-ceutical industry. About Sartorius Sartorius AG is an internationally leading process technology

DlSCOVER®

Our audit and survey services:– Compliance audits– Regulatory inspection readiness– Plant|Process surveys– Validation surveys– Quality system surveys– Technical studies

lNCREASE®

Our optimization services: – Corrective actions guidance – Process optimization and

development support – Design review and technology transfer – Documentation and submittal optimization – Regulatory guidance

CONFIDENCE®

Our validation services:– Validation designs– Pre-approval inspection preparation– Post-approval change support– CFR 21 Part 11|GAMP compliance– Regulatory liaison– Equipment qualification– Filter|Cleaning|Process validation– Extractables|Leachables testing

EXPAND®

Our training services:– FDA risk-based approach– Regulatory inspection– CFR 21 Part 11|GAMP– Aseptic processing– Upstream|Downstream processing– Process validation– Cell culture|Fermentation– lntegrity testing– Quality control and quality assurance

These services are provided by experiencedexperts in collaboration with our BioPharm-Alliance partner.

Page 14: MidiCaps and Mini Cartridges for the biopharma- ceutical ... · for the biopharma-ceutical industry. About Sartorius Sartorius AG is an internationally leading process technology

Ordering Information

MidiCaps® and Filter Capsules Type 150 & 300

Type Pore Filtration Area Filtration Area Filtration Area Filtration Area Filtration Area Filtration AreaSize (µm) 0.015 m2|0.15 ft2 0.03 m2|0.3 ft2 0.05 m2|0.5 ft2 0.1 m2|1 ft2 0.2 m2|2 ft2 0.45 m2|4.8 ft2

Sartobran P 0.45 5231306D5OOB 5235306D7��A 5235306D8��A 5235306D9��A 5235306D0��V0.2 5231307H4��B 5231307H5OOB 5235307H7��A 5235307H8��A 5235307H9��A 5235307H0��V0.1 – 5235307H7��A 5235358H8��A 5235358H9��A 5235358H0��V

Sartopore 2 0.45 5441306G5OOB 5445306G7��A 5445306G8��A 5445306G9��A 5445306G0��V0.2 5441307H4��B 5441307H5OOB 5445307H7��A 5445307H8��A 5445307H9��A 5445307H0��V0.1 5441358K4��B 5441358K5OOB 5445358K7��A 5445358K8��A 5445358K9��A 5445307K0��V

Sartolon 0.2 – – – 5105307H9��A –

Sartofluor 0.45 – 5185306T7��A 5185306T8��A 5185306T9��A –0.2 5181307T4��B 5181307T5OOB 5185307T7��A 5185307T8��A 5185307T9��A –0.1 – 5185358T7��A 5185358T8��A 5185358T9��A –

Sartoclean CA 0.8 – 5625304E7��A 5625304E8��A 5625304E9��A 5625304E0��V0.65 – 5625305G7��A 5625305G8��A 5625305G9��A 5625305G0��V0.45 – 5625306A7��A 5625306A8��A 5625306A9��A 5625306A0��V0.2 – 5625307A7��A 5625307A8��A 5625307A9��A 5625307A0��V

Sartoclean GF 0.8 – 5605304E7��A 5605304E8��A 5605304E9��A 5605303E0��V0.65 – 5605305G7��A 5605305G8��A 5605305G9��A 5605304G0��V

Sartopure PP2 50 5591350P5OOB 5595350P7��A 5595350P8��A 5595350P9��A 5595350P0��V20 5591320P5OOB 5595320P7��A 5595320P8��A 5595320P9��A 5595320P0��V8 5591301P5OOB 5595301P7��A 5595301P8��A 5595301P9��A 5595301P0��V5 5591342P5OOB 5595342P7��A 5595342P8��A 5595342P9��A 5595342P0��V3 5591302P5OOB 5595302P7��A 5595302P8��A 5595302P9��A 5595302P0��V1.2 5591303P5OOB 5595303P7��A 5595303P8��A 5595303P9��A 5595303P0��V0.65 5591305P5OOB 5595305P7��A 5595305P8��A 5595305P9��A 5595305P0��V

Sartopure GF 1.2 – 5575303P7��A 5575303P8��A 5575303P9��A 5575303P0��VPlus 0.65 – 5575305P7��A 5575305P8��A 5575305P9��A 5575305P0��V

�� Please replace the blanks with the appropriate two-letter combination for the capsule connectors (see order code information).

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Ordering Information

Mini Cartridges

Cartridge Pore Size| Filtration Area Filtration Area Filtration AreaType Retention Rating (µm) 0.05 m2|0.5 ft2 0.1 m2|1 ft2 0.2 m2|2 ft2

Sartobran P 0.45 5231506D7 B 5231506D8 B 5231506D9 B0.2 5231507H7 B 5231507H8 B 5231507H9 B0.1 5231558H7 B 5231558H8 B 5231558H9 B

Sartopore 2 0.45 5441506G7 B 5441506G8 B 5441506G9 B0.2 5441507H7 B 5441507H8 B 5441507H9 B0.1 5441558K7 B 5441558K8 B 5441558K9 B

Sartolon 0.2 – – 5101507H9 B

Sartofluor 0.45 – 5181506T8 B 5181506T9 B0.2 5181507T7 B* 5181507T8 B* 5181507T9 B*0.1 5181558T7 B 5181558T8 B 5181558T9 B

Sartoclean CA 0.8 – 5621504E8 B 5621504E9 B0.65 – 5621505G8 B 5621505G9 B0.45 5621506A7 B 5621506A8 B 5621506A9 B0.2 5621507A7 B 5621507A8 B 5621507A9 B

Sartoclean GF 0.8 5601504E7 B 5601504E8 B 5601504E9 B0.65 5601505G7 B 5601505G8 B 5601505G9 B

Sartopure PP2 50 – – 5591550P9 B20 – – 5591520P9 B8 – – 5591501P9 B5 5591542P7 B 5591542P8 B 5591542P9 B3 5591502P7 B 5591502P8 B 5591502P9 B1.2 5591503P7 B 5591503P8 B 5591503P9 B0.65 5591505P7 B 5591505P8 B 5591505P9 B

Mini cartridges with a filtration area 0.05 m2|0.5 ft2 or 0.1 m2|1 ft2 are optionally available with construction code 18.

* Sartofluor Mini cartridges with a 0.2 µm pore size are optionally available with construction code 12.

How to order: Sartobran P, Construction Code 15, 0.2 µm, Filtration Area 0.2m2

5 2 3 1 5 0 7 H 9 – – – – – – B

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Verkürzte Einklappseite!

Order Code InformationCode Cartridge Type

523 Sartobran P544 Sartopore 2510 Sartolon518 Sartofluor562 Sartoclean CA560 Sartclean GF559 Sartopure PP2555 Sartopure GF Plus

Code ConstructionMini

15 Bayonet type18 Double O-Ring 13 150 & 30053 MidiCaps

Code Pore Size Final Filter [µm]

50 5020 2001 842 502 303 1.204 0.805 0.6506 0.4507 0.258 0.1

Code Pore Size Pre Filter [µm]

A No prefilterP Only polypropy-

lene layersT Only one teflon

membraneE 3 µmG 0.8 µmD 0.65 µmH 0.45 µmK 0.2 µm

Code Filtration Area

4 0.015 m2|0.15 ft2

5 0.03 m2|0.3 ft2

7 0.05 m2|0.5 ft2

8 0.10 m2|1 ft2

9 0.20 m2|2 ft2

0 0.45 m2|4.5 ft2

Code O-Ringe forCartridges and Capsules

– – Silicone– E EPDM– V Viton

Code Capsule Connectors SizeN 4” NPT Thread Only Type

150 & 300S 1” Tri-Clamp (sanitary) Only Type 150H 4” multiple stepped MidiCaps

hose barb (only Size 7)Type 150 & 300

F 3” Tri-Clamp (sanitary) MidiCapsO 1” single stepped MidiCaps

hose barbS 1 1” Tri-Clamp (sanitary) MidiCaps

Code Pack Size V Box of 2A Box of 4B Box of 5

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Page 18: MidiCaps and Mini Cartridges for the biopharma- ceutical ... · for the biopharma-ceutical industry. About Sartorius Sartorius AG is an internationally leading process technology

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No.

: 850

30-5

06-4

1

Sales and Service ContactsFor further contacts, visit www.sartorius.com

EuropeGermanySartorius AGWeender Landstrasse 94–10837075 Goettingen

Phone +49.551.308.0Fax +49.551.308.3289

www.sartorius.com

Sartorius BBI Systems GmbHSchwarzenberger Weg 73–7934212 Melsungen

Phone +49.5661.71.3400Fax +49.5661.71.3702

www.sartorius.com

U.K.Sartorius Ltd.Longmead Business ParkBlenheim Road, EpsomSurrey KT19 9 QQ

Phone +44.1372.737100Fax +44.1372.720799

AustriaSartorius Ges.m.b.H. WienFranzosengraben 12A-1030 Vienna

Phone +43.1.7965763.18Fax +43.1.796576344

BelgiumSartorius Technologies N.V.Leuvensesteenweg, 248/B1800 Vilvoorde

Phone +32.2.756.06.80Fax +32.2.756.06.81

DenmarkSartorius Nordic A/SHimmelev Bygade 494000 Roskilde

Phone +45.70.23.4400Fax +45.46.30.4030

FranceSartorius S.A.S.4, rue Emile Baudot91127 Palaiseau Cedex

Phone +33.1.6919.2100Fax +33.1.6920.0922

ItalySartorius S.p.A.Via dell’Antella, 76/A50012 Antella-Bagno a Ripoli (FI)

Phone +39.055.63.40.41Fax +39.055.63.40.526

IrelandSartorius LimitedUnit 41, The Business CentreStadium Business ParkBallycoolin RoadDublin 11

Phone +353.1.8089050Fax +353.1.8089388

NetherlandsSartorius Technologies B.V.Edisonbaan 243439 MN Nieuwegein

Phone +31.30.6025080Fax +31.30.6025099

SpainSartorius, S.A.C/Isabel Colbrand 10 –12, Planta 4, Oficina 121Polígono Industrial de Fuencarral28050 Madrid

Phone +34.91.3586102Fax +34.91.3588804

SwitzerlandSartorius Schweiz AGLerzenstrasse 218953 Dietikon

Phone +41.1.746.50.00Fax +41.1.746.50.50

AmericaUSASartorius North America, Inc.131 Heartland Blvd.Edgewood, New York 11717

Phone +1.631.254.4249Toll-Free +1.800.3687178Fax +1.631.254.4253

Sartorius BBI Systems, Inc.2800 Baglyos CircleBethlehem, PA 18020

Phone +1.610.866.4800Fax +1.610.866.4890

ArgentinaSartorius Argentina S.A.Calle Avalos 4251 (B1605ECS) MunroBuenos Aires

Phone +54.11.4721.0506Fax +54.11.4762.2333

BrazilSartorius do Brasil Ltda.Rua Santo André, 33109020-230 Santo AndréSão Paulo

Phone +55.11.4438.3833Fax +55.11.4438.2355

MexicoSartorius de México, S.A. de C.V.Circuito Circunvalación Poniente No.149Ciudad Satélite53100 Naucalpan, Estado de México

Phone +52.55.62.1102Fax +52.55.62.2942

Asia|PacificChinaBeijing Sartorius Instrument & SystemEngineering Co., Ltd.– Beijing Rep. Office –Dong Hu Qu, Wang Jing Industrial ZoneChao Yang District 100102 Beijing, P.R.C.P.O. Box 8516

Phone +86.10.6439.2552Fax +86.10.6439.2726

Sartorius Ltd.Unit 1110-12, Lu Plaza, 2 Wing Yip StreetKwun Tong, Kowloon, Hong Kong

Phone +852.2774.2678Fax +852.2766.3526

IndiaSartorius India Private Ltd.10, 6th Main, 3rd Phase PeenyaKIADB Industrial AreaBangalore – 560 058

Phone +91.80.2839.1963|0461Fax +91.80.2839.8262

JapanSartorius K.K.KY Building, 8-11 Kita Shinagawa 1-chomeShinagawa-kuTokyo 140-0001

Phone +81.3.3740.5407Fax +81.3.3740.5406

South KoreaSartorius Korea BiotechB-1023, Paragon17-2, Jungja-Dong, Bundang-Gu Sungnam, Gyunggi-Do463-811, South Korea

Phone +82.31.782.7011Fax +82.31.782.7666

MalaysiaSartorius (Malaysia) Sdn. Bhd.Lot L3-E-3B, Enterprise 4Technology Park MalaysiaBukit Jalil57000 Kuala Lumpur

Phone +60.3.8996.0622Fax +60.3.8996.0755

SingaporeSartorius Singapore Pte. Ltd.10, Science Park Road, The Alpha#02-25, Singapore Science Park 2Singapore 117684

Phone +65.6872.3966Fax +65.6778.2494

AustraliaSartorius Australia Pty. Ltd.Unit 17/104 Ferntree Gully RoadWaverley Business ParkEast Oakleigh, Victoria 3166

Phone +61.3.9590.8800Fax +61.3.9590.8828