mHealth_PRESENTATION_LifeScience+cluster_15102013

8/21/2019 mHealth_PRESENTATION_LifeScience+cluster_15102013

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© 2013 Tampere Region Economic Development Agency Tredea Ltd.



• Tredea cluster information materials - 7 key clusters:

• Intelligent Machines, Life Science, ICT, Manufacturing Industry

• + in process: Creative Business Industries, Cleantech, Nanotech, Energy

• Life Science (Healthtech+Biotech)

1. Short presentation = Cluster Description: key figures, key actors, keyarguments

2. Background material: top 20 companies, key research institutes + their

projects

3. Backgound material: company list (92) incl. Key figures (turnover,

turnover growth%, employees), competences, offering, contacts

• From april to end of June 2013

• Interviews (35 companies+organisations )

• Round Table 7.6.2013

•

Statistics/company data from: Taloussanomat, Tilastokeskus, Toimialaon-line, FiHTA, FIB



• Key questions:

• Cluster Definitions - The relevance of defining?

• Cluster Development/Cluster Policy – the Relevance?

• How can we use this information?

• How can it benefit the business in Tampere region?

Questions



1. Finland- Focus on High Technology Industries

2. Tampere Area- Good in Size

- Smooth Collaboration between Research and Business

3. Key Players

4. Core Competences

5. Life Science Cluster- Cross Sectoral Business

6. Core R&D

- 3 Universities, 12 Research Institutes and Centres of Expertise

7. Local and Global Networks

8. Summary: Why Tampere?



- High level education system (TOP ranking in PISA

studies)

- Excellent availability of scientists and engineers

- Good public innovation platforms and funding

- National public funding on solutions

for biological information (e.g. 10M€ BioIT

Programme 2013-2015)

- Private investments on Life Science

companies 65M€ (2012)

- Transparent and effective national regulation,

licensing, and legislation

- “Rocketing” health tech export: 1,65 billion € in

2012. Annual growth (2011-2012) 23 % (not incl. R&D

labour and services)

- Health technology is appr. 2,5 billion € 2012

business in Finland (combined turn over of members of

Finnish Health Technology Association)

Finland = Safe, well organized, smooth and functional

infrastructure, transparent public administration.

• 350 M€ annual public funding on health sector R&D.

Source: Ministry of Employment and Economy

“Technology Industries are the most

important industrial sector in Finland:

• 60% of total Finnish exports

• 80% of total Finnish R&D-investments

• 290 000 directly employed in the sector, total

employment effect around 700 000, equalling aquarter of the Finnish workforce.”

Source: The federation of Finnish Technology Industries



“"The modern way of life presents a hazard to our well-being. By using

our skills in mobile technologies and behavior science, we can do a lot

to make people to change their health behavior for better. "

Movendos Oy, Arto Leppisaari, CEO

Our strenghts:

• Unique combination of Bio – Medi

– Tech –expertise in research and

education

• Cutting edge medical development

in Personalized Medicine andHuman spare parts

• Expertise in Connected Health:

Strong ICT & Medical Engineering

• Cross sectoral health services and

service know how

"Tampere is one of the few places in the

world where biosciences and technology

work together in such a closeconnection."

– Technical University of Tampere,

Jukka Lekkala, Professor



Because we have:

• Good size enabling smooth collaboration

• Functionable infrastucture making it easy to do

business and research

•

Skilled and motivated personnel available forfluent recruitment

• BioMediTech - A pioneering research and

educational environment combining

biosciences and technology

Tampere - First in Finland and

Northern Europe:

1783: 1st paper mill

1842: 1st paper machine

1882: 1st electric light in

Northern Europe

1974: 1st Biomedical chairs in Finland

2006: 1st clinical cranial bone fixation

derived from patients’ own fat

tissue in the world

Tampere Today:

• Fastest growing region in Finland

• Up to 15% of Finland's national

R&D budget is spent here

• with the population of 490 000

- the largest region in Finland just

after the Helsinki capital region

“For an investor, the size of Tampere provides

an advantage. Things run smoothly, andinvestors can be personally involved in

shaping their business environment.”

- Jyrki Liljeroos, CEO Santen Ltd



Tekes, BioIT

programme, ELY-

center

B-to-b, b-to-c, b-to-b-to-c

Devices, ICT, Software,

Integration, Pharma, Services,

Biomaterials

Patient hotel, Senior housing service

concept, Private hospital and health

services , Sports institutes

New Factory business

incubator: Protomo,

Demola, Suuntaamo

mHealth network

Data Driven

Medicine conf

CLUSTER

COORDINATION

AND NEW

INNOVATION

PLATFORMS

FinnMedi Innovation,

Growth, Clinical

FUNDING AND EXPERTISE 100+ COMPANIES LINKED SERVICE PROVIDERS

ENABLERS AT

SCIENCE PARK KAUPPI

Hermia Ltd FinnMedi Ltd.

RESEARCH AND EDUCATIONTampere University of

Technology, TUT

University of

Tampere, UTA

Institute of Biosciences and Medical

Technology, BioMediTech

Tampere University of

Applied Sciences, TAMK

VTT Technical

Research

Centre of

FinlandThe Pirkanmaa

Hospital District,Science Center

Coxa

Hospital

for JointReplacement

UKK Institute, Centre for Health

Promotion Research

Heart Center

Tampere University Hospital,

TAUH

Research and

Development Center for

Ophthalmic Innovations,

SILK

Research Centers:

FICAM, GEREC ,

TACC, Regea,

FinMIT, Vaccine

Research

National Institute for Health

and Welfare/Tampere



KEY COMPETENCES APPLICATION AREAS BUSINESS EXAMPLES

Stem cells

Cell and tissueBiomimetic environments

Biomaterials and biosensors

Implantable spare partsIn vitro drug discovery

Biodegradable materials

OzicsBioretecScaffdex

Signal and image processingICT and SW engineering

Computational systemsbiology

Monitoring and imagingSensor and measurement solutions

Connected health

Bionavis

Physiotools

Mylab

Health informaticsHealth care processes

Rehabilitation and trainingGerontology

Wellness and health care systemsSpecialized health care units

Assistive technologiesTreatment and care

CoxaNorlandiacare

Instainnovation

Drug development

Immunology & geneClinical research

VaccinesOphthalmology medicineMitochondrial genetics

Cancer

Santen

VactecFitBiotech

Human

spare parts

Biomedical

systems and

devices

Health

services

Medicines

Universities and research institutions Innovation platforms University hospital Research centers &institutes



Stem Cells

and

TissuesBiosensors

Bio-

mimectic

environ-

ment

Immuno-logy &

Gene

Drug

Develop-

ment

Clinical

reseach

Bio-

materials

Electronics

Microscale

Techno-

logies

ICT &

Signal

Processing

Health

Infor-

matics

Health

Care

Processes

Rehab,

Training &

Geronto-

logy

Implantable

spare partsCell & tissue

center and data

baseIn vitro drug

discovery

Biodegradable

materials

Vaccines

Mitochondrial

genetics

Ophthalmology

medicine

Assistive

technologies

Wellness and

health care

systems

Personal health

informatics

Connected

Health

Computational

Biology

Specialized

health care

units

Treatment andcare

Sports and

wellness

tourism

Human

Spare Parts

Biomedical

systems and

devices

Medicines

Health

Services

Biobanks

Sensor andmeasurement

solutions

Monitoring and

Imaging



Ophthalmic

medicines and

methods

Santen.fi

Preclinical

vaccine dev.

and biobanking

Vactec.fi

DNA plasmids,

HIV-vaccine dev.

Fitbiotech.com

Biocomposite

implants in sports

medicine

Conmed.com

Insta Care situational

awareness system

Instainnovation.fi

Coxa Focus

Hospital for Joint

Replacement

Coxa.fi

Patient Hotel

Norlandiacare.no

Custom assistive

devices and

related services

incl. prosthesisRespecta.fi

SPR Surface

Plasmon

Resonance

Bionavis.com

Software for

personalised

exercise handouts

Physiotools.com

iPana birth

information

platform

Mediware.fi

Balance Trainer

Platform

Hurlabs.com

Mobile coaching

solution

Movendos.com

Biomaterials and

implants for

mending bones

Ozics.com

Bioabsorbable

implants and

devices for surgery

Bioretec.com

App for

sports&training

Sports-tracker.com

App for

sports&training

Trelab.fi

Healthcare

information

services

Mylab.fi

Biodegradable

solutions to surgery

Inion.com

Phrenic nerve

stimulators

Atrotech.com

Human

Spare Parts

Biomedical

systems and

devices

Medicines

Health

Services



• Biomaterials

• ICT & Signal

Processing

• Drug Development

Ophthalmology

medicine

Santen Pharmaceutical specializes in the research,

development, manufacturing and marketing of

ophthalmic and anti-rheumatic pharmaceuticals to

protect and improve people's eyesight and health.

Santen.fi

•

Health CareProcesses

ConnectedHealth

Specialized

health care

units

Biodegradable

materials

Movendos Ltd is a start-up developing mobile tools

for personal health & wellness coaching. With this

tool coaches can follow customers progress, motivate

them and measure the effectiveness of coaching inreal time. Movendos is a spin-off from TUT personal

health research. Movendos.com

Coxa Hospital for Joint Replacement is a health care

pilot company, a focus hospital, founded in 2002.Coxa has cutting edge expertise in both joint

replacement surgery and research.

Coxa.fi

Bioretec Ltd manufactures and develops advancedbioabsorbable implants and device solutions for

various fields of surgery. Bioretec’s Activa products

are novel bioabsorbable fixation devices for

treatment of bone ligament and cartilage fractures.

Bioretec.com

Human Spare Parts

Health Services

Biomedical systems

and devices

Medicines

http://www.santen.eu/

http://www.movendos.com/

http://www.coxa.fi/

http://www.bioretec.com/

http://www.bioretec.com/

http://www.coxa.fi/

http://www.coxa.fi/

http://www.movendos.com/

http://www.santen.eu/



Tampere

Region:

Life Science Industries(Bio and Health Technology)

Technology Industries (total)

Companies 100 2 700

Employees 2 000 34 400

Turn over 436 m € 7 751 m €

(source: local estimation based on public company

data 2012, and interviews)

(source: The Federation of Finnish Technology

Industries)

FACT FILE: Tampere• Good size

• “90 min accessibility” - logistically excellent

• The oldest industrial town in Finland:

• Industry-oriented

• Business friendly

• Easy to reach by car, by train, by airplane



Cutting edge expertise in:

•Biomaterials

• Biodegradable materials

• Regenerative medicine and stem cell technology combination of

• Biomaterials

• Sensors

• Imaging

• Cellular biology

• Signal and image processing in biomedical applications

• Personal health informatics and m-health

• Cell technology

• Computational system biology

• Personal medicine

" Here in Tampere, having access to extensive

patient material and follow-up data, we have

excellent opportunities for research."

-Coxa Oy, Tarmo Martikainen, CEO

Cross-disciplinary co-operation environment

where engineers, biologists, and medical

experts work together.



• Innovation. Tampere innovation

platforms:

• Supporting start-up and growth of the

companies

• FinnMedi• New Factory, Protomo

• Enablers. Early testing environments

• Tampere University Hospital

• Heart Center

• SILK R&D Center for Ophthalmic

Innovations• Coxa Hospital for Joint Replacement

• Business. Tekes and other national

support systems

• From research to business

• Active start-up scene

"Tampere has many logistical benefits for our

supply chain: fast deliveries from our central

warehouse, skilled workforce with health care

certificates, standardised and certified

products, and the backing of up-to-date

research."

-Respecta Oy, Satu Forsman, Area Manager

Finn-Medi Science Park,

Kauppi campus



• International level research

• Universities and research institutes

• Fidipro programme to invite

international experts to

Tampere universities

• National research programmes• Shok-cooperation (Salwe, Tivit)

• Finnish Academy

• Tekes

• Cross-disciplinary research and education

• Joint education programme including engineering, biological

and medical studies• BioMediTech research coordination

• Specialized research centersCoxa Hospital for Joint Replacement, FICAM Finnish Centre for Alternative Methods, Heart Center,

Regea Cell and Tissue Center, Science Center at the Pirkanmaa Hospital District, SILK Research

and Development Center for Ophthalmic Innovations, Surgery Training Center, Vaccine Research

Center

"The expanding, global industry of health care

technologies has a hub of expertise here in

Tampere.“- VTT Technical Research Centre of

Finland , Niilo Saranummi, professor

Technical research

centre of Finland



• Mining and fusion of human data

• Mobile health and wellness

applications

• Health information systems

•Health Tourism

•Health Gaming

•Social Robotics

•Usability testing and living labs

• Immunology

• Cell and tissue, Stem cells

• Gene and protein technology

• Gerontology

•

Regenerative medicine• Vaccines

• Vision and Ophthalmology

• Image and signal processing

• Biomaterials and biosensors

• Computational systems biology

• SW engineering, User interfaces

• Micro- and nanoscale technologies

• Personal health informatics

University

of Tampere

Technical research

centre of Finland,Tampere

Tampere University

of Applied Sciences

Unipoli Tampere Agreement (since 2006) Active mentoring programmes

COMPANIES

FinnMedi Research

Joint institute of

University of Tampere and

Tampere University of Technology

• Combination of engineers,

biologists and clinicians• Strategic research in biomedicine

and medical technology

Researchers : 250+

Profs: 20

Researchers: 200

Students: 100 (total 10 400)

Profs: 50

Researchers: 300

Students: 800 (total 16 000)

Researchers : 30 (total 340) Students: 500 (total 10 000)



Information processing, modelling and control


• User interface, user experience, usability

Materials and devices

• Biomaterials, biosensors, microscale technologies

Electronics, mechanics, physics, chemistry

Medicine

• Microbiology, immunology

• Virology, Vaccines

Health sciences

• Biostatistics, Cancer, Ageing

Strategic multi-disciplinary research

combining

• Engineers

• Clinicians

• Biologists

Human data mining

• Biosignal and image analysis

• Mining and fusion of heterogeneous data

Connected health

• Mobile health and wellness applications


Medical and wellness technologies

• Biomedical Laboratory Sciences

• Wellness technology

Health care practices

• Physiotherapy









Medicine



Health sciences

• Biostatistics, Cancer, Ageing


combining

• Engineers

• Clinicians

• Biologists

Human data mining



Connected health







• Physiotherapy

To develop solutions leading in the future to

new therapies and drug screening technologies

such as:

• Bone transplants• Cardiac cell and tissue models

for studying genetic heart diseases and drug

development.

Combines top-level

expertise in

biomaterials, sensor

technology, biomedical

engineering and

stem cells

Human Spare Parts Program









Medicine



Health sciences• Biostatistics, Cancer, Ageing


combining

• Engineers

• Clinicians

• Biologists

Human data mining



Connected health







• Physiotherapy

• Mimicking human in vivo conditions (normal

and diseased)

• Understanding stem cell biology

• Understanding disease mechanisms

• Studying effects of chemical compounds

Technologies for

measuring and

controlling the

conditions in the cell

microenvironment

Biomimetic Cell Cultivation

Environments









Medicine





combining

• Engineers

• Clinicians

• Biologists

Human data mining



Connected health







• Physiotherapy

• Signal and image processing methods for

automatic analysis of 3D functional images

• Computational modeling and sensing of tissue

engineered and physiological systems• Automatic methods for the analysis of brain

images

• Neuroinformatics combines neuroscience and

informatics research to develop tools to

understand the structure and function of the

brain

Developing methods

and software for

processing and

analysing of properties

and functionality of

biological systemsthrough imaging and

modeling

Image Analysis and Modeling









Medicine





combining

• Engineers

• Clinicians

• Biologists

Human data mining



Connected health







• Physiotherapy

•Objective and strictly evidence based analysis,

• Integrates heterogeneous biomarkers from blood

samples, imaging data (MRI+PET), TMS/EEG and

clinical tests

•Estimates disease severity not just provide a

classification and works with incomplete data

•Currently being tested for clinical use in several

trials, licensed to commercial use and in use in

several research projects

Development of

novel biomarkers

and analysis

software for early

diagnosis of theAlzheimer's

disease

PredictAD: Decision Support System









Medicine





combining

• Engineers

• Clinicians

• Biologists

Human data mining



Connected health







• Physiotherapy

•Giving patients tools to gather, manage, analyse

and communicate their health information

between other patients and health professionals

•Personal health monitoring

•Personal data management (PHR)

•Personal analysis and feedback

•Connectivity

•Monitoring + Communication + Data

Interpretation + UX + SW engineering + Business

Model

Design health

technologies for

consumer.

”People as co-

producers of health

and care” React ive

Proact ive

Health & Care

Professionals

Cit izen-

Patient

C o n n e c t e d

H e a l t h

c h o i c e s

Dependency

Patients as

passive objects

Individuals as

co-producers of

Health & Care

People as co p roducers of health and care

Consumer Health Informatics









Medicine





combining

• Engineers

• Clinicians

• Biologists

Human data mining



Connected health







• Physiotherapy

• Biodegradable materials are used as drug carriers

to allow for the drug to be released directly into

the bloodstream to make it available to thewhole body, or locally into the damaged tissue.

• Materials can be employed to treat diseases that

require the use of multiple drugs.

• Can also be used to repair tissue

• Implant acts both as a drug-release device

and as a cell scaffold.

Targeted drug

delivery through

new biodegradable

materials that

release drugs to the

human body

Drug Delivery and

Biodegradable Materials









Medicine





combining

• Engineers

• Clinicians

• Biologists

Human data mining



Connected health







• Physiotherapy

TAMK Tampere University of

Applied Sciences

R&D focus in Bio and Health

Technology:

• Health tourism

• Technologies and services for senior citizens

• Health gaming and social robotics

• Young athletes wellness programme

•

ITSE- and UNI-Living labs for testingusability of tools, devices and technologies

related on sleep and housing

“TAMK offers Bachelor and Master level studies for 10 000

students in seven educational fields. The education focuses

on technology, business and wellbeing services.”



Focus Hospitals:

• Coxa Hospital for Joint Replacement: 173 specialist of which 18 doctors. Scientific research and

development work on joint replacement surgery, related processes and therapies. www.coxa.fi

• Heart Center: 300 specialists of which 50 doctors. Scientific research focusing on development of

angioplasty techniques and enhanced protection of the heart during cardiac surgery, patient’s

post-operative quality of life, and magnetic navigation system (Niobe®Stereotaxis ).

www.sydankeskus.fi

Research Centers :

• FinMIT The Academy of Finland Centre of Excellence conducts research on mitochondrial disease

and ageing in institute of Biomedical technology at University of Tampere. www.uta.fi/ibt/finmit

• Regea Cell and Tissue Center is a clinical tissue bank processes and supplies tissues for clinical use

in institute of Biomedical technology at University of Tampere. Regea also produces adipose tissue

derived stem cell products for the treatment of bone defects. www.regea.fi

• SILK Research and Development Center for Ophthalmic Innovations at the University of Tampere:

coalition of 60 specialists focusing on proteomics of personalized medicine, imaging techniques,

stem cell technology and clinical research of the eye. http://www.silkresearch.fi/

• Science Center at the Pirkanmaa Hospital District: Supporting researchers all the way from

planning to clinical phase and from finance and juridical advicing.

• Surgery Training Center: Surgical training specializing on tissue and joint surgery - The only high

level surgical education center in Northern Europe.

• The UKK Institute Centre for Health Promotion Research: R&D projects to generate information

on the health benefits and promotion of physical activity. http://www.ukkinstituutti.fi/en/research

http://www.coxa.fi/

http://www.sydankeskus.fi/

http://www.uta.fi/ibt/finmit/

http://www.regea.fi/

http://www.silkresearch.fi/

http://www.ukkinstituutti.fi/en/research





http://www.regea.fi/



http://www.sydankeskus.fi/

http://www.coxa.fi/



Research Centers within the University of Tampere:

• Finnish Centre for Alternative Methods, FICAM : focuses on the

development and validation of cell and tissue culture 2D and 3D models to

complement and replace animal tests. http://www.ficam.fi/

• Gerontology Research Center, GEREC: produces new scientific

knowledge for the aging society, contributes to academic training andincreases expertise in the field of aging. A joint institute with the University of

Jyväskylä.

• Tampere Center for Child Health, TACC : (est.2012) 100 staff members

and research students. TACC brings together laboratory scientists,

psychologists, social scientists, public health specialists as well as clinicians

from paediatrics, child psychiatry and other medical specialties. TACC

carries out multidisciplinary research with a wide range of methodologies,aiming at improved means to promote and resume healthy growth among

infants and children worldwide.

• Vaccine Research Center: 130 professionals forming a clinical research

unit operating within the University of Tampere Medical School. It carries out

clinical trials of vaccines in co-operation with the pharmaceutical industry.

http://rokotetutkimus.fi

http://www.ficam.fi/

http://rokotetutkimus.fi/

http://rokotetutkimus.fi/

http://www.ficam.fi/



•FinnMedi Ltd: Networking, business development and clinical

research in the Life Sciences sector. http://www.finnmedi.fi

• Innovation and growth services for companies and research groups

•Coordination of National expertise programmes focusing on health

applications of biotechnology and on business areas related to healthand well-being.

•Hermia Ltd: Networking and acceleration of expertise in

technology industry. http://www.hermia.fi/

•Nanotechnology cluster programme focusing on fotonics

and future composite materials.

• Joint networking with FinnMedi: Data Driven Medicine conference and

mHealth Tampere Network

•FIB Finnish Bioindustries: Finland's biotechnology industry association representing

all life science areas, from health care and functional food to biomaterials.

http://www.finbio.net/en/finnish-bioindustries

•FiHTA The Finnish Health Technology Association: is the association for all Finnish companies in the

health technology business. http://www.finnishhealthtech.fi/

•The European Connected Health Alliance (ECHAlliance): Comprising companies, health and socialcare providers and research organisations across Europe.

http://www.finnmedi.fi/

http://www.hermia.fi/


http://www.finnishhealthtech.fi/

http://www.finnishhealthtech.fi/




http://www.hermia.fi/

http://www.finnmedi.fi/



TAMPERE ALL BRIGHT!

Where eng ineers,

bio log ists and c l in ic ians

coll ide.

• Excellence in research

• Good size for smooth

collaboration

• Unique multidisciplinary high

level education

• Competitive business

development• Highly skilled professionals

available

"We are convinced that in the near future, by

means of technological expertise, Tampere

will provide a pioneering solution to welfare

problems caused by the aging population."

- Insta Innovation Oy,

Esa Einola, Vice President

CONTACT: Mr Petri Nykänen

[email protected]

Director, Business Development and Invest in

CONTACT: Mr Reijo Itkonen

[email protected]

Director, Business Development

mHealth_PRESENTATION_LifeScience+cluster_15102013

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