Methomin SPL
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Transcript of Methomin SPL
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Dr Ganesh K Saini
Product Manager - Poultry
The Assurance Minerals
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Classified into two groups: Macro or major elements (required > 100 ppm) 7 macro minerals are Ca, P, Mg, Na, K, Cl and S
Micro or trace mineral elements (required
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Soil Plant
Bird
Relationship
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Emerging Nutrient Deficiencies in soils as a Result of Increased Food Production (Swarup & Ganeshamurthy, 1998)
Year 1950 1960 70 80 1990 2000
Food
Production
50mt 70mt 108 112 172 209mt
Emerging
Nutrient
Deficiencies
?
N N N N N N
Fe Fe Fe Fe Fe
P P P P
Zn Zn Zn Zn
K K K K
S S S
Mn Mn Mn
B B
?
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REGIONS Minerals deficient in feeds
Northern Ca , P , Mg, Zn ,Cu, Mn, I,
Western Ca, P, S, Cu, Zn,
Southern Ca, P, Mg, Cu, Zn,
Eastern Ca, P, Mg, Mn, Cu, Zn, Co,
Mineral Deficiency in feeds All
India
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The arrows indicate
the relationship
between the minerals.
If a mineral has an
arrow pointing to
another mineral, it
indicates that mineral
is a requirement for
absorption.
How to Interpret the
Mineral Wheel
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Sub-Clinical Clinical
Immune Function
Growth or Fertility
Clinical Signs
Time
Min
era
l S
ta
tu
s
Mineral Deficiency
Response
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10
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TRACE MINERAL ABSORPTION
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Zn+2
Zn+2
Ingested
CB - 50
Outcome 1. Excretion
Blood
Gut Wall
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Zn+2
Zn+2
Zn+2
Ingested
CB - 50
Outcome 2. Excretion
Antagonist
Blood
Gut Wall
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Zn+2
Zn+2
Zn+2 +
Ingested
CB - 50
Complexing
Agent
Outcome 3. Natural Success
Blood Zn+2
Gut Wall
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Ingested
Gut Wall
Engineered for Success
Zn+2
Zn+2
Zn+2
Zn+2
Zn+2 BLOOD
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What about Chelation?
Chelation . . . The process by which metal ions form a
complex with an organic ligand via a coordinate bond.
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From: Holwerda, R. A., R. C. Albin and F. C. Madsen (1995) Chelation effectiveness of zinc proteinates demonstrated, Feedstuffs, June 19, 1995, 12-13 and 23.
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Assured Response
Assured Results
Assured Bioavailability
Assured Returns
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Complexed to Metal
Amino Acid
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22
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TRACE MINERALS ARE NOT
THE SAME
Sulfates
Proteinates
EDTA
Oxides Carbonates
Chlorides Chelates complex
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Metal (Specific Amino Acid) Complex
Metal Amino Acid Chelate
Metal Amino Acid Chelate
Metal Proteinate
Metal Polysaccharide Complex
Metal Propionate
CPX - 22
DIFFERENTIATION OF ORGANIC TRACE MINERALS
Zn+2 Prop.-1 Prop.-1
Zn AA
AA AA AA
Zn Zn
AA AA
Zn Zn
Zn Zn
Zn Zn
Zn Zn Zn Zn
Zn Zn Zn
Zn
Zn Zn
Zn
Met Zn
AA Zn AA AA
AA AA
AA
AA AA AA AA
AA AA
AA
AA AA AA
AA AA
AA
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Absorption
SIZE MATTERS
Need to be
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SMALLER IS BETTER!
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ORGANIC TRACE MINERAL COMPARISON (Based on AAFCO)
PROTEINATE
M
M
360
Daltons
1065
Daltons
AFFCO Definition of Proteinate: The product resulting from the chelation of a soluble salt with amino acids and/or partially hydrolyzed protein
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THIS IS ALSO A PROTEINATE
6365 Daltons
AFFCO Definition of Proteinate: The product resulting from the chelation of a soluble salt with amino acids and/or partially hydrolyzed protein
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DIGESTION
Most Large Peptides and Protein Ligands will be
Broken Into Single Amino Acids, Di- or Tripeptides
for absorption
The Digestion Process Will Destroy the Weak
Bond Between the Metal and the Peptide or
Protein Ligand
Z CPX - 38
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Relative Stability Constant of OTM
0
20
40
60
80
100
120
Amino Acid Di- Peptide Tri- Peptide Peptide (4
AA)
Peptide (5
AA)
Stability Constant %
LIGAND TYPE
Rel
ati
ve
Sta
bil
ity
Co
nst
an
t %
Science also confirms that as the ligand
size increase the ability of the ligand to
form a strong bond decrease rapidly.
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FORMULATION STRATEGIES FOR LOWERING TRACE MINERAL
SUPPLEMENTATION LEVELS
Parameter
Increasing Trace Mineral Level
Inorganic Complexes
Nutrient Utilization Status vs. Time and Level Performance Single Source - All Complexes Immunity Environment
CB - 42.2
Inorganic + Antagonists
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Parameters Methomin Bioplex
Type Amino acid Chelate Proteinate
Metal Bond 1:2 (metal: AA) Metal bonded with a protein
molecule
Molecule Size Below 360 dalton More than 1000 dalton
Composition 40,40,5,15 of Zinc,
Manganese, Copper and
Iron respectively.; Iodine and
chromium thru inorganic
route and Se thru Selenium
yeast route.
Research Published data mostly in
popular magazines
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Prevent Deficiency
Normal growth
Normal Repro
Normal immunity
Increased growth
Improved Efficiency
Improved Reproduction
Improved immunity
STANDARD MINERALS
Assurance
MINERALS
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Assured Response
Assured Results
Assured Bioavailability
Assured Returns
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35 35
Methomin SPL
Zinc 40 grams
Manganese 40 grams
Copper 10 grams
Iron 12 grams
Chromium 250 mg
Iodine 4 grams
Selenimum 300 mg
Cobalt 250 mg
Mixing Rate : 0.5 - 1 Kg / MT
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Per Kg METHOMIN TOTAL Contains
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Advantage of Methomin
Egg quality: shell quality,albumin quality,nutritional value of egg, free
from defects.
Zinc helps in activation of carbonic anhydrase and formation of cuticle
Blood plasma - shell gland - egg shell
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Benefits
Source of methionine.
Reduction in egg shell breakage.
Improvement in egg shell quality.
Improvement in hatchability
Growth and feed efficiency.
Improves egg production.
Better performance during heat stress
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MHA V/S DLM
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MHA DLM
Absorbed throughout the intestinal tract Absorbed mainly in the ileum
Absorption is a passive process Is active process
Converted to L-methionine much faster Comparatively slower conversion
Absorption is unaffected by heat stress Decreases during heat stress
Non-toxic at higher doses Toxic at higher doses
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Objective
1. Reduction of antagonism, interferences and competition among
minerals.
2. Improve the bioavailability of minerals
3. Counteract antinutritional factors, which affecting minerals
4. Performance improvement
5. Health improvement (immune status, functional nutrition)
6. Over all animal welfare
7. Improvement in animal produces quality (meat, milk, egg, wool etc.,)
8. Reduce degenerative effect of trace minerals on vitamins in premixes
feed.
9. Protect environment by reducing metal pollution.
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Mixing Rate and Presentation
Mixing Rate : Poultry -0.5-1Kg/ton of feed
As recommended by the Nutritionist
Presentation : 25Kg.
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