Meningitis, Encephalitis and Brain Abscess_aaims_HBD_IV-1[1]
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Transcript of Meningitis, Encephalitis and Brain Abscess_aaims_HBD_IV-1[1]
Meningitis and Encephalitis:
MeningitisEncephalitisBrain abscess
Diagnosis and Treatment Update
Germaine Daley BSc, MSc (Clinical Microbiology)
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Objectives
Infections of the Nervous System
Meningitis
Encephalitis
Brain absess
C. Nolts
Infections of the Nervous System
Can include infections of the meninges (meningitis), the general brain parenchyma(encephalitis), or a focalized infection of the brain parenchyma (brain absess)
General Sx are fever and headache. Other Sx will exist depending on the etiology/nature.
Infections of the Nervous System
Untreated or improperly treated=high mortality
Neonates, young people, adults, old people, and immunocompromised(HIV) are distinctly different populations and this categorization is essential
Definitions
Meningitis inflammation of the meninges
Encephalitis infection of the brain parenchyma
Meningoencephalitis inflammation of brain + meninges
Aseptic meningitis inflammation of meninges with sterile CSF
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Meningitis:
bacterial
viral
fungal
aseptic (Lyme, syphillis)
TB
Other causes of aseptic meningitis:
malignancy
NSAIDs
chemo
abx
Common causes of meningitis
#1 cause:
S. pneumoniae- in adults, very prevalent in others
N. meningitidis-in young people, characteristic rash
S. agalactiae (GBS)-in neonates
Other prominent causes:
Listeria-in children