1

CURRICULUM VITAE

MEHREEN LATEEF

Personal Information

Husband’s Name: Akber Ali

Father’s Name: Abdul Lateef Khan

Sex: Female

NIC No: 42000-0357355-2

Marital Status: Married

Nationality: Pakistani

Date of Birth: 26th November 1980

Address: K-8 Cosy Homes, Gulshan-e-Iqbal, Karachi

Telephone No: 92346-3273597

E-mail: meher_khan555@hotmail.com

Education

Ph.D in Biochemistry on from Department of Biochemistry, University of

Karachi, Pakistan under the supervision of Prof. Dr. Abid Azhar, Dean

Sciences & Director General KIBGE and cosupervision of Prof. Dr. Bina S.

Siddiqui, HEJ, in 2013.

M. Phil in Biochemistry on under the supervision of Dr. Abid Azhar from

Department of Biochemistry, University of Karachi in 2007.

M.Sc in Biochemistry from University of Karachi with First Class (75 %) in

2002.

B.Sc (Honours) in Biochemistry from University of Karachi with First Class (65%) in 2001.

H.S.C from Karachi Board with Biology, Chemistry & Physics with Grade

(71%) in 1997.

S.S.C from Karachi Board with Biology, Chemistry & Physics with Grade

(76%) in 1995.

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Dissertation/ Thesis title

Ph.D “Synthesis Of Potential Aromatic Analogues With Special Reference to Antiplatelet

Activity”

M.Phil “Serum Leptin in Postmenopaual Women with Osteoporosis: its Relation to

Biochemical Bone Markers”

M.Sc “Relationship of Leptin with Reproductive Hormones FSH, LH and Estrogen in Normal

Healthy Females”

Working Experience

May-2015- Onwards Working as Head of Department of Multi-disciplinary lab and Senior

Assistant Professor in Department of Biochemistry, Bahria

University Medical and Dental College.

April 2015- July-2005 Worked as Scientific Officer in Pharmaceutical Research Centre of

PCSIR laboratories Complex

Jan-June, 2012 Worked as Research Scholar for six months on “Biochemical

signaling pathways involved in blood platelets” from Department

of Biomedical Sciences of Heritage College of Osteopathic Medicine,

Ohio University, Athens, Ohio, USA

June- July, 2010 Worked as Researcher in Biochemistry lab to establish some assays

in enzyme inhibition lab of Islamia University, Bahawalpur.

Jan 2003-June 2005 Worked as Lecturer of Biochemistry in Liaquat College of Medicine

& Dentistry, Karachi.

Current Status

Developed postgraduate research lab and Working as Head of Department of Multi-disciplinary lab

and Assistant Professor in Biochemistry Department in Bahria University Medical and Dental

College.

Involved in Pharmaceutical, Biotechnological and Biochemical Research Projects

Isolation, Purification and Characterization of β-galactosidase from Microbial Source.

Biological activities of compounds isolated from native wild flora of Karachi

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Enzyme Inhibition Activities of Naturally Isolated and Synthetic Compounds

Human Serum Analysis for Antioxidant Parameters (Glutathione, superoxide dismutase, total

antioxidant activity, endothelin, C reactive protein) by Kit methods in Cardiac patients

Effect of Haptoglobin gene polymorphism on Heat Shock Protein and other Markers in type II

diabetic patients with and without nephropathy.

Bioequivalence and Bioavailability of Isoquinonoe group of drugs

Shelf life of Mutton, Beef & Camel Meat

Stability Studies of Ferromate Tablets (210 mg) LDPE jar at intermediate conditions

ORS Liquid Product Stability studies

Preparation of value added Enzyme based products for gastrointestinal disorders.

Evaluation of medicinal Plants including , Litchi chinensis, Achras sapota L., Rubus niveus, Alstonia

scholaris, Annona squamosa and Eriobotrya japonica, in addition the study and analysis of their

chemical constitutes

Biological activities of synthethic anthraquinones & Carbamate Derivatives

Stability Studies of lactase for lactose Intolerance

Evaluation of Biochemical Signaling Pathways involved in Platelet Aggregation inhibition pathway

of new anthrarobin derivatives.

Antiplatelet Studies involving aggregation and secretion in human platelet rich plasma and

washed platelets against various inducers.

Molecular Analyses of Human Human P2Y12 (Agonist-bound Structure receptor) function

reducing gene mutation/ polymorphism will be done by PCR-RFLP and direct DNA sequencing.

Development of various assays of Enzyme inhibition studies against new synthetic and isolated

compounds or drug including antioxidant, urease, tyrosinase, cholinesterase, chymotrypsin and

lipoxygenase inhibition.

Instrument Handling

UV Spectrophotometer

ELISA Plate Reader

Gas Chromatography

HPLC (automated and manual)

Aggregometer

Flow Cytometer

PCR

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Training Given

Training given to various students or internees on pharmaceutical techniques including

dissolution, disintegration, friability, hardness and determination of active ingredient by HPLC,

GC/MS for qualitative and quantitative analysis of pharmaceutical products

And also provide expertise on ELISA training to professionals too.

Conferences/Seminars/Workshops participated in

2017

Participated in TRAIN THE TRAINER BIOPRISM LABORATORY SAFETY TRAINING

INITIATE PROGRAM (March 29-31 March, 2017) organized by Pakistan Biological Safety

Association and National Institute of Health, USA in Islamabad.

Presented On Biosafety in Biological Laboratories in one day seminar on Advanced Tools &

Techniques for Biological Evaluation of Medical Devices with Reference to ISO-10993

organized by Biochemistry and Biotechnology Section PCSIR.

2016

Presented on leptin and osteoporosis (July, 28th, 2016) in Dr. Saleem-uz- Zaman Sidduiqui

Lecture Series organized by Seminar Committee PCSIR Laboratories Complex Karachi.

2015

Participated in Dr. A. Q. Khan Winter School on “ Modern Tools & Techniques in Health &

Diseases” the workshop of “Planning, Excecution and Accomplishment of Research

Degrees” (Dec 25-27,2015) at KIBGE, Karachi.

2014

Participated in the workshop of “Planning, Excecution and Accomplishment of Research

Degrees” (April 26-28) at KIBGE, Karachi.

Participated in the workshop of “The Use of Excel Macros & Microsoft Tools for Data

Handling & Performing Complex Data Analysis, Involving a Wide Range of Software.

(April 18-19) at KIBGE, Karachi.

2013

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Presented a paper on “Butryl cholinesterase inhibition and docking studies of newly

synthesized anthrarobin derivatives” in 5th Chemistry Conference 2013 on “Chemistry in

Engineering and Life Sciences” (November 04-06) organized by Pakistan Atomic Energy

Commission, Islamabad.

Participated in the workshop of “Statistical analysis of GWAS Genome World Wide

Association Studies” (Oct. 28-29) at KIBGE, Karachi.

2012

Participated in the fourth ICLS-KIBGE International Conference on SCIENCE, TECHNOLOGY

&ENGINEERING: INNOVATIVE, YET RESPONSIBLE! Organized by International Council for Life

Sciences (ICLS) and KIBGE of "Manuscript writing Bioinformatics Resources for Drug

Research” (November 28-30) at HEJ Institute of International Centre For Biological and

Chemical Sciences, Karachi (Oct 18).

2011

Presented a Paper on “Relationship of serum leptin with BMD in postmenopausal

osteoporosis” in first symposium of “1st IOF-ESCEO Preclinical Symposium and ECCEO-IOF

Congress, 22-23 March 2011, Valencia, Spain (March 22-23).

Presented a Paper on “Relationship of Age, BMI, Serum Calcium and Estradiol with BMD in

Postmenopausal Osteoporotic Females” in first symposium of “Health and Education: Need

of the Nation” at Bahria University Medical & Dental College, Karachi (Feb. 4-6).

2010

Presented a poster on “Serum leptin & telopeptide C levels in postmenopausal

Osteoporotic Females” osteoporosis in 49th Annual Medical Symposium at JPMC, Karachi

(Feb. 15-21).

Presented a Paper on “Serum Calcium Levels and Bone Mass Density in Pre and

Postmenopausal Females with and without Osteoporosis” in an International conference on

“Recent Advances on Human Nutrition with Special References to Vulnerable Groups” at

National Institute of Food Science & Technology University of Agriculture, Faisalabad (Feb. 22-

25).

Participated in the workshop of “Bioinformatics Resources for Drug Research” at HEJ

Institute of International Centre for Biological and Chemical Sciences, Karachi (Nov. 28-30).

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Presented a Paper on “Relation Ship of Leptin and Bone markers in Postmenopausal

Osteoporosis” in the 10th Biennial Conference of Pakistan Society for Biochemistry and

Molecular Biology (PSBMB) on Bimolecular Sciences In Development at Dr. A.Q Khan Institute

of Biotechnology and Genetic Engineering (KIBGE), Karachi (Dec. 1-5).

2009

Participated in the workshop of "Antiplatelet Properties of Naturally Occurring Chemicals in

Pakistani Herbs / Plants" at KIBGEE, Karachi (Nov. 16-25).

2008

Presented a paper on “Relationship of osteocalcin and BMD in osteoporosis” in 35th All

Pakistan Science Conference) at International Centre for Chemical and Biological Sciences

(ICCBS) auditorium, Karachi (Dec. 20-23).

2007

Presented a paper on “Biochemical Bone Markers n Postmenopausal Osteoporosis” in

“World Health Updates” at Expo Centre, Karachi (Jan. 26-28).

Participated in “Research Protocol Development Work Shop” at Dr. Panjwani Centre for

Molecular Medicine and Drug Disease International Centre for Chemical and Biological Sciences

(ICCBS), University of Karachi (March 8-10).

2006

Attended 9th International Symposium on “Protein Structure Function Relationship” at

International Centre for Chemical and Biological Sciences (ICCBS), Karachi (Jan. 11-14).

Presented a paper on “Significance of carboxyterminal telopeptide (Telopeptide-c), in

diagnosis of type 1 osteoporosis.” in 43rd Annual Medical Symposium on Disaster

Management of Jinnah Postgraduate Medical Centre, Karachi (March 6-9).

Presented a paper on “Estimation of serum osteocalcin and carboxy terminal telopeptide

of type 1 collagen (telopeptide-c) in postmenopausal osteoporotic females” in 2nd Annual

Symposium of Dow University of Health Sciences on “Changing Priorities… Journey from

Curative to Preventive Medicine” (Dec 26-29).

2005

Presented a paper on “Comparison of BMD in pre and Postmenopausal Females” in 8th

Biennial National Conference on Emerging Trends in Biochemistry & Molecular Biology at Dept.

of Biochemistry, University of Karachi. (March 7-9).

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Participated in Higher Education Commission Workshop on “Trends in Teaching of

Biochemistry as Basic Science for Medicine & Dentistry” at Liaquat College of Medicine and

Dentistry, Karachi (March 14-17).

2004

Participated in Symposium on “Biochemistry in post genomic era” at Department of

Biochemistry, University of Karachi (Dec 5-8).

2003

Participated in Workshop on “Statistical Methods in Research with Special Reference to

Applied Biology.” at Department of Biochemistry, University of Karachi (Jan 27-29).

Presented a paper on “Leptin and reproductive hormones During Late Follicular and

Luteal Phases of Menstrual Cycle in Normal Healthy Females” in 7th International

Conference on Trends in Biochemistry and Molecular Biology, Lahore (April 2-5).

2002

Participated in Workshop on “Information Handling in Biological Research” at Department

of Biochemistry, University of Karachi (March 4-6).

Publications

2017

1. New anthrarobin acyl derivatives as butyrylcholinesterase inhibitors: synthesis, in

vitro and in silico studies Mehreen Lateef, Abid Azhar, Bina S. Siddiqui , Shamshad

Zarina , Nizam uddin , Muhammad F. Anwar, Kauser Siddiqui, Kaniz F. Azhar , Lubna

Iqba , Rashad Mehmood, Shagufta Perveen. Heliyon 3 (7),3-7

2. Antioxidant and Enzyme Inhibitory Constituents from Dactyladenia floribunda and

Chemicals Transformations of Hennadiol .Adjapmoh Essombo Martial Flora, Mbaze

Meva’a Luc Leonard, Wansi Jean Duplex, Muhammad Shaiq Ali, Kamdem Waffo Alain

François, Takou Dieudonné Martial, Mehreen Lateef .Natural Products Chemistry and

Research (Accepted).

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3. Viridone, A New Butyrylcholinesterase Inhibitory Phenolic Ester From Leaves Of Ocimum

Viride. Almas Hashmi, Muhammad Shaiq Ali, Mehreen Latif, Zeeshan Ahmed and Joseph

Ngoupayo. Chemistry of Natural Compounds (Accepted).

4. Piptadenin, a Novel 3,4-secooleanane Triterpene and Piptadenamide, a New Ceramide

from the stem bark of Piptadeniastrum africana (Hook. f.) Brenan. Mbiantcha, Yannick

Fongang, William Yosseu Nana, Fawai Yakai, Gilbert Ateufack, Muhammad Ali Shaiq,

Iqbal Lubna, Mehreen Lateef, Bonaventure Tchaleu Ngadjui Chem Biodivers, 2017 14

(02) 5.

5. Native Wild Plants in Karachi, Pakistan: Rich Source of Antioxidant Raw Material”

Mehreen Lateef, Sadia Farheen, Kauser Siddiqui, Beena Naqvi and Lubna Iqbal Pakistan

Journal of Pharmaceutical Sciences Accepted 2016.

2016

6. A New Ceramide and Biflavonoid from the Leaves of Parinari hypochrysea

(Chrysobalanaceae).Martial F E Adjapmoh, Flavien A A Toze, Jules L Songue, Moses

K Langat, Gilbert D W F Kapche, Abdul Hameed, Mehreen Lateef, Muhammad A

Shaiq, Luc M Mbaze, Jean D Wansi, Alain F W Kamdem Nat Prod Commun

May;11(5):615-20.

7. 1,2,3,4,6-Pentakis[-O-(3,4,5-trihydroxybenzoyl)]-α,β-D-glucopyranose(PGG)

analogs: design, synthesis, anti-tumor and anti-oxidant activities. Qurat-Ul-Ain

Shaikh, Meiting Yang, Khadim Hussain Memon, Mehreen Lateef, Du Na, Shengbiao

Wan, Deslandes Eric, Lijuan Zhang, Tao Jiang. Carbohydr Res, Jul 28; 430:72-81.

8. Antimicrobial, antioxidant and butyrylcholinesterase inhibition activities of extracts

and isolated compounds from Scadoxus pseudocaulus and semi-synthetic farrerol

derivatives A.L. Ngankeu Pagning , Jean-de-Dieu Tamokou , M. Lateef Khan , M.

Imran Ali , Abdul Hameed b , David Ngnokam , L. Azefack Tapondjou a , Jules-Roger

Kuiate c , M. Shaiq Ali .South African Journal of Botany 102 (2016) 166–174

9. New triterpene and new flavone glucoside from Rhynchospora corymbosa

(Cyperaceae) with their antimicrobial, tyrosinase and butyrylcholinesterase

inhibitory activities Annie Laure Ngankeu Pagninga,b , Jean-de-Dieu Tamokouc ,

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Mehreen Lateefd , Léon Azefack Tapondjoua , Jules-Roger Kuiatec , David

Ngnokama, *, Muhammad Shaiq Alib, * Phytochemistry Letters 16 (2016) 121–128.

2015

10. Evaluation of in vitro antioxidant capacity and reducing potential of polyherbal drug

Entoban. Sadia Shakeel* Khan Usmanghani Somia Gul Zeeshan Ahmed Sheikh Syed

Faisal Zaidi Mehreen Lateef African Journal of Pharmacy and Pharmacology, 29(40)

:982-987

11. Cashmins A and B, Potent Antioxidant Coumarins from Sorbus cashmiriana

Sadia Khan, Itrat Fatima, Mehdi Hussain Kazmi, Abdul Malik, Nighat Afza, Lubna

Iqbal, Mehreen Latif Chemistry of Natural Compounds,51:4 626-629.

12. Copper (II) Complexes of Bishydrazone Derivatives: Synthesis, Characterization and

Urease Inhibition Studies Muhammad Asad Khan Tanoli, Zahid Khan, Zaahida T.

Maqsood, Lubna Iqbal, Mehreen Lateef, Zahid HussainMiddle-East Journal of

Scientific Research 22 (5): 698-703, 2014

13. Synthesis, Characterization, In-Vitro Antimicrobial and Antioxidant Activities of

Co+2, Ni+2, Cu+2 and Zn+2 Complexes of 3-(2-(2-hydroxy

methoxybenzylidene)hydrazono)indolin-2-one Zahid Khan1,, Zahida T. Maqsood1,

Muhammad Asad K. Tanoli, Khalid M. Khan,Lubna Iqbal and Mehreen Lateef.

Journal of Basic & Applied Sciences

14. Antioxidant potential of anthrarobin (1,2,10- trihydroxy anthracene) and its acyl

derivatives Mehreen Lateef, Nizammuddin, Sobiya Pervaiz, Bina S. Sidduiqui,Saeeda

Bano, Abid Azhar, Kanwal Abbassi, Kauser Sidduiqui, Kaniz Fizza Azhar. Journal of

Chemical Society of Pakistan. 10/31/2015, Vol. 37 Issue 5, p1015-1019. 5p.

15. Flavonoids and other bioactive constituents from Ficus thonningii Blume (Morceae).

Yannick S.F. Fongang, Jean J.K. Bankeu, Muhammad S. Ali, Angelbert F. Awantu ,

Ahmed Zeeshan , Clement N. Assob, Lateef Mehreen, Bruno N. Lenta , Silvere A.

Ngouela, Etienne Tsamo. Phytochemistry Letters, 11:139-145.

2014

16. Unsymmetrical 1,3-disubstituted urea derivatives as α-chymotrypsin inhibitors

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Shahnaz Perveen, Sana Mustafa, Mehreen Latif, Lubna Iqbal, Tanzil H. Usmani,

Khalid Mohammed Khan, Wolfgang Voelter. Medicinal Chemistry Research, online

ISSN: 1554-8120

17. Role of protein denaturing agents and EDTA on α-amylase activity from Bacillus

subtilis KIBGE HAS Saeeda Bano, Mehreen Lateef, Samina Iqbal, Beena Naqvi and

Lubna Iqbal International Journal of Pharmaceutical, Chemical and Biological

Sciences, 4(2), 411-415.

2013

18. Urease inhibitory isoflavonoids from different parts of Calopogonium mucunoides

(Fabaceae), Brigitte. Ndemangou, Valerie Tedjon Sielinou, Juliette Catherine

Vardamides, Muhammad Shaiq Ali, Mehreen Lateef, Lubna Iqbal, Nigaht Afza,

Augustin Ephrem Nkengfack, Journal of Enzyme Inhibition and Medicinal Chemistry,

28 (6),1156-61.

19. Synthesis, Spectroscopic characterization and pharmacological evaluation of

oxazolone derivatives, Ghulam Fareed, Uzma Rasheed Mughal, Mehboob Ali

Kulhoro, Lubna Iqbal, Mehreen Lateef, J. Serb. Chem Soc, 78(8) 1127-31.

20. Structure activity relationship: Antioxidant potential of some novel Schiff bases

containing benzophenone moiety, Ghulam Fareed, Muhammad Ali Virsiani, Nighat

Afza, Nazia Fareed, Lubna Iqbal and Mehreen Lateef, International Journal of

Current Pharmaceutical Research, 5, 61-64.

21. Phytochemical screening of total phenolic contents and and biological evaluation of

aerial parts of Nepeta praciervisa, G Fareed, N. Afza, A. Malik, M.A. Versiani, M.

Lateef, N. Fareed, U.R Mughal, R.B. Tareen and L. Iqbal, J. Chem. Soc. Pak.,

35(5)1364-1368.

22. A Potent Urease Inhibitor: 2-{[(2-{[€-(Hydroxyphenyl)Methyllidene]Amino}Ethyl I

Methyl} Phenol-Copper ((li) Complex NighatAfza, ItratAnis, M.Aslam, A

Hussain,M.Safdar, A.H. Chaudry, Lubna Iqbal, MehreenLateef, a. Qayyum, M. Niaz.

and Tahir Rehman. International Journal of Current Pharm ,83-85.

23. Antioxidant activity and structure activity relationship of some new Schiff bases

derived from 2-Aminobenzophenone, Ghulam Fareed, Nighat Afza, Muhammad Ali

Versiani, Nazia Fareed, Lubna Iqbal, Mehreen Lateef and Tahir Rehman, Medicinal

Chemistry & Drug Discovery, 27-34.

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24. Anthrarobin and its derivatives: evaluation of antibacterial and lipoxygenase

inhibition activities. Mehreen Lateef, Samina Iqbal, Nizam uddin, Bina S. Siddiqui

and Abid Azhar, Pak. J. Biochem. Mol. Biol., 46(2): 59-61

2012

25. Ophiamides A_B, New Potent Urease Inhibitory Sphingolipids from ophiogoglossum,

Sadiqa Firdous,Nida Hassan Ansari,Itrat Fatima, Abdul Malik, Nighat Afza, Lubna

Iqbal, Mehreen Lateef, Arch. Pharm. Res., 35(7), 1133-1137.

26. Bioactive Phenolic Amiides from Celtis Africana, Areej Mohammad, Al-Taweeel,

Shagufta Perveen, Azza Muhammad El-Shafae, Ghada Ahmed Fawzy, Abdul Malik,

Nighat Afza, Lubna Iqbal and Mehreen Latif, Molecules, 17, 2675, 2682.

27. Biologically Active Bergenin Dervatives from Bergenia stracheyi, Farah Siddiq, Itrat

Fatima, Abdul Malik, Nighat Afza, Lubna Iqbal, Mehreen Lateef, Saira Hameed and

Sher Wali Khan, Chemistry & Biodiversity, 9, 91-98.

28. Potent Antioxidant and Lipoxygenase Inhibitory Flavonone and Chalcone from

Erythrina mildbraedii Harms (Fabaceae) of Cameroon, Muhammad Shaiq Ali,

Muhammad Imran Ali, Ghafoor Ahmed, Nighat Afza, Mehreen Lateef, Lubna Iqbal,

Alain F.K. Saffo and Zeeshan Ahmed, Z. Naturforsch, 67b, 98-102.

29. Evaluation of Antioxidant and Urease Inhibition activities of roots glycyrrhiza

glabra, Mehreen Lateef, Lubna Iqbal, Kauser Siddiqui, Nudrat Fatima, Nighat Afza,

Zia ul Haq, Mansoor Ahmed, Pakistan Journal of Pharmaceutical Sciences, 25(1), 99-

102.

30. Estimation of Monosodium Glutamate by modified HPLC method in Various

Pakistani Spices' Formula, Mehreen Lateef, Kauser Siddiqui, Muhammad Saleem,

Lubna Iqbal. Journal of Chemical Society of Pakistan, 34(1), 39-42.

31. A one-pot synthesis, characterization and pharmacological investigations: Schiff

bases, I. Anis, M. Aslam, N. Afza, A. Hussain, F. S. Ahmad, L. Iqbal, M. Lateef, M. T.

Hussain, and T. H. Bokhari, International Journal of Pharmaceutical Chemistry, 2(3),

73-77.

2011

32. Bio reactive properties of citrus waste: An investigation of antioxidant and

tyrosinase inhibitory activities, Musarrat Akhtar, Lubna Iqbal, Mehreen Lateef,

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Bushra Nawab, Muhammad Saleem and Nighat Afza, Pakistan Journal of Botany,

43(6), 2881-2883.

33. Potent Antioxdant and Lipoxygenase Inhibitory flavanone and Chalcone from

Erythrina mildbraedii (Fabaceae) of Cameroon. M.S Ali, G.Ahmad, M.I. Ali, L.Iqbal,

N.Afza, M.Lateef, Alain..F,K. waffo, Z. Ahmad, Zeitschrift fuer Naturforshung B 67B

2011 p 98-102.

34. Sorbicins A and B, new urease and serine protease inhibitory triterpenes from

Sorbus cashmiriana, Mehdi Hassan Kazmi, Itrat Fatima, Abdul Malik, Lubna Iqbal,

Mehreen Latif and Nighat Afza, Journal of Asian Natural Products Research, 13(12),

1081-1086.

35. Antixodant and urease inhibitory C-glycosylflavonoids from Celtis Africana, Shagufta

Perveen, Azza Muhammad El-Shafae, Areej Al-Taweel, Ghada Ashmed Fawzy, Abdul

Malik, Nighat Afza, Mehreen Latif and Lubna Iqbal, Journal of Asian Natural

Products Research, 13(9), 799-804.

36. Allo-Imperatorin: A Potent Urease Inhibitor from Fresh Unripe Fruits of Aegle

marmelos (Rutaceae), Muhammad Shaiq Ali, Ghafoor Ahmed, Muhammad Kashif

Pervez, Mehreen Lateef, Nighat Afza and Lubna Iqbal, J. Chem. Soc. Pak., 33(6), 960-

964.

37. Relationship of leptin with BMD in postmeopausal osteoporosis, Lateef M., Baig, M.

and Azhar A., Osteoporosis International; 23S.

2010

38. Conferin, Potent antioxidant and Antiinflammatory isoflavone from Caragana

Conferta, S. Naz, I Fatima, N. Riaz, N. Afza, A. Malik, M. Lateef and L. Iqbal, Journal of

Enzyme Inhibition & Medicinal Chemistry, 25: 440-444.

39. Estimation of serum osteocalcin and telopeptide-C in postmenopausal osteoporosis,

Mehreen Lateef, Mukhtiar Baig, Abid Azhar, Osteoporosis International, 21:751-755.

40. Relationship of Age, BMI, Serum Calcium and estradiol with BMD in postmenopausal

osteoporotic Females, Mukhtiar Baig, Mehreen Lateef, Abid Azhar, Journal of

Bharia University, Medical & Dental College, 2:25-29.

2009

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41. Mutiniside, New Antioxidant Phenolic Glucoside from Abutlion muticum, S. Ali, S.

Yasmeen, N. Afza, A. Malik, M. Lateef, N. Riaz, M. Ashraf, Journal of Asian Natrual

Product Research, 11, 457-464.

42. Lipoxygenase Inhibitory Tetraketones; Potential Remedial Source for inflammation

and Asthma, S. Ali, G. M. Mharvi, N. Riaz, N. Afza, A. Malik, M. Lateef and L. Iqbal,

West Indian Medical Journal, 58:93-95.

43. Asphorodin, Potent Lipoxygenase Inhibitory Triterpene Diglycoside from

Asphodelus tenuifolius, S. Khan, S. Yasmeen, N. Riaz, N. Afza, A. Malik, M. Lateef and

L. Iqbal, Journal of Asian Natrual Products Research, 11: 945-950.

2008

44. Structural determination of salsolins A and B, new antioxidant polyoxygenated

triterpens from Salsola baryosma by 1D and 2D NMR spectroscopy, Zaher Ahmad,

Sajid Mehmod, Itrat Fatima, Abdul Malik, Rehana Ifzal, Nighat Afza, Lubna Iqbal,

Mehreen Lateef and Tanver Ahmad Nizami, Magnetic Resonance in Chemistry, 46:

94-98.

45. New butryl cholinesterase Inhibitory Steroid and Peroxy acid from Leucas

Utricifolia, Itrat Fatima, Ijaz Ahmed, Itrat Anis, Abdul Malik, Nighat Afza, Lubna

Iqbal, and Mehreen Lateef, Archieves of Pharmceutical Resonance, 31: 999-1003.

46. Mild and efficient syntheses of lipoxygenase inhibiting and antioxidant tetraketones,

Ghulam Murtaza Maharvi, Samar Ali, Naheed Riaz, Nighat Afza, Abdul Malik, M.

Ashraf, Lubna Iqbal and Mehreen Lateef, Journal of Enzyme Inhibition and Medicinal

Chemistry, 23:62-69.

47. Cotonoates A and B, new aromatic esters from Cotoneaster racemiflora, Shafiullah

Khan, Shazia Yasmeen, Nighat Afza, Abdul Malik, Lubna Iqbal and Mehreen Lateef,

Z. Naturforschung, 63:1219-1222.

48. Studies On Amylase Activity Of Pancreatin Obtained From Bovine Pancreas, Zaman

Niazi, Kauser Siddiqui, Lubna Iqbal and Mehreen Lateef, Pakistan Journal of

Scientific and Industrial Research, 51, 242-244.

2006

49. Determination of Radical Scavenging Activities and Reduction Capabilities of

Tetraketones derived from 5, 5-dimethyl-1, 3 cyclohexanedione, Lubna Iqbal, Samar

14

Ali, Mehreen Lateef, Abdul Wahab Zahid and Nighat Afza, Pakistan Journal of

Biochemistry and Molecular Biology, 39:36-40.

50. Role of Coriandrum Sativum as antioxidant, Lubna Iqbal, Mehreen Lateef, Abdul

Wahab Zahid, Nudrat Fatima, Nighat Afza, Pakistan Journal of Biochemistry and

Molecular Biology, 40: 95-98.

51. Antioxidant activities of tetraketones derived from 5,5 dimethylcycohexane-1,3-

dione, L. Iqbal, M. Lateef, S. Ali, N. Riaz, G. M. Maharvi, M. Ashraf and N. Afza, Journal

of Chemical Society of Pakistan, 29: 51-54.

52. Leufolins A and B, potent Butyrylcholinesterase inhibiting Flavonoid Glucosides

from Leucas urticifolia, Atia-tun-Noor, Itrat Fatima, Ijaz Ahmed, Abdul Malik, Nighat

Afza, Lubna Iqbal, Mehreen Lateef, Sher Bahadur Khan, Molecules, 12: 1447-1454.

53. Correlation between circulating leptin and gonadotrophins during the menstrual

cycle in infertile females, Mukhtiar Baig, Abid Azhar, Mehreen Lateef and Perveen

Zaidi, Pakistan Journal of Biochemistry & Molecular Biology, 40:115-119.

2005

54. Role of Serum Osteocalcin in Diagnosis of Postmenopausal Osteoporosis, Mehreen

Lateef,Mukhtiar Baig & Abid Azhar, Pakistan Journal of Biochemistry & Molecular

Biology, 38: 56-60.

2003

55. Depression of Plasma Testosterone Level by Heroin Addiction and its Restortion by

the Withdrawl of the Drug, Abid Azhar, Arif Siddiqui, Nosheen Afzal, Mukhtiar Baig

and Mehreen Lateef, Pakistan Journal of Biochemistry & Molecular Biology, 36: 73-

78.

Total Publications = 55 International= 44 National = 11

CHAPTER PUBLISHED IN BOOK

Serum Leptin and Bone Turnover Markers In Postmenopausal Osteoporosis

Mehreen Lateef, Mukhtiar Baig, Abid Azhar Topics in Osteoporosis, 2013 Dr. Margarita

Valdés-Flores (Ed.), ISBN: 978-953-51-1066-8, InTech, DOI:

15

10.5772/54527.http://www.intechopen.com/books/topics-in-osteoporosis/serum-leptin-

and-bone-turnover-markers-in-postmenopausal-osteoporosis

Patent

1. “A Process for the Preparation of Lactase free Milk supplement for Lactose Intolerant

Population” Mehreen Lateef, M. Saleem Qazi, Lubna Iqbal, Nighat Afza

SI no 1205/2008.

2. A Process for the preparation of an analgesic cream for joints and arthritis pain

Kauser Siddiqui, KanwalAbbasi, MehreenLateef, Muhammad Saleem, Lubna Iqbal,

Muhammad Riaz, Kaniz Fizza Azher, SI no: 141669.

3. A Process for the Preparation of Topical Analgesic Cream for Traumatic Pain

Kauser Siddiqui, Samina Iqbal, MehreenAkber, Kanwal Abbasi, Muhammad Saleem,

Saeeda Bano, Lubna Iqbal. Accepted Application no: 605/2013

Computer Skills

Having knowledge of Microsoft Word, Excel, PowerPoint, Publisher, Picture Manager,

Visio, Statistica etc.

Member of Organizing Committee

2005 Member of Organizing Committee of Higher Education Commission Workshop on

“Trends in Teaching of Biochemistry as Basic Science for Medicine &

Dentistry”

2003 Member of Organizing Committee of Workshop “Statistical Methods in Research

with Special Reference to Applied Biology”

2003 Member of Organizing Committee of International Symposium “Plant

Biotechnology: Recent Perspectives”

2002 Member of Organizing Committee of Workshop “Information Handling in

Biological Research”

2002 Member of Organizing Committee of “Biochemica” as a researcher.

16

Awards

2012 Awarded as “Best Mentor” for supervising six projects and training of students of various

colleges participated in Intel Science Exhibition and selected as winner at national and

international level.

2005

Awarded third prize of “Young Scientist Award” on presenting a paper in 8th Biennial National

Conference of Pakistan Society of Biochemistry & Molecular Biology.

Member ship

Pakistan Journal of Biochemistry and Molecular Biology

Organization of women in Science for the Developing Board (OWSD)

International Journal of Orthopaedics

Editorial Board Journal of Bahria University Medical and Dental College

References

Prof. Dr. Abid Azhar

Director General Karachi Institute of Biotechnology and Genetic Engineering University of Karachi, 75270. Pakistan. Tel: 9221-34823884 Email: abid.azhar@kibge.edu.pk

Dr. Lubna Iqbal Principal Scientific Officer Pakistan Council of Scientific and Industrial Research Laboratories Complex, Karachi-75280. Pakistan. Tel: 9221-34642894-98 Ext.27 Email: lubnaiqbal95@yahoo.com

Prof. Dr. Mukhtiar Baig Professor Faculty of Medicine Rabigh, King Abdulaziz University, Jeddah,

17

Kingdom of Saudia Arabia Email: drmukhtiarbaig@yahoo.com

Dr. Huzoor Akbar Assosiate Professor of Pharmacology, Department of Biomedical Science, Irvine Hall 416, Ohio University, Athens, Ohio, USA. Tel: 740-593-2406 Email: akbar@ohio.edu