Mega Bio Cluster Creation for InnovationPolicy; Infrastructure; Human Resource; Networking;

Mittur N. Jagadish, PhDHead - Biotech Facilitation CellKBITS- Department of IT BT and S&TGovernment of Karnataka

Area: 191,791 km2

Population: ~62 Million & counting / sec

Cha

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CHALLENGES – PERSISTAgriculture

Energy Environment

HealthWHY?

BIOTECH (4 major sub sectors)

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Agriculture

Energy Environment

Health

TECHNOLOGY INVENTIONS - UTILIZED

Polio Vaccine 170X 106

solar wind

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MORE of OLD + NEW CHALLENGESAgri Tech

Energy Tech Green Tech

Med TechHowever,

Need New Technologies

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Particle class Materials Application

Natural materials or derivatives

ChitosanDextraneGelatineAlginatesLiposomesStarch

Drug/Gene delivery

Dendrimers Branched polymers Drug delivery

Fullerenes Carbon based carriers PhotodynamicsDrug delivery

Polymer carriers

Polylactic acidPoly(cyano)acrylatesPolyethyleinemineBlock copolymersPolycaprolactone

Drug/gene delivery

Ferrofluids SPIONSUSPIONS Imaging (MRI)

Quantum dots Cd/Zn-selenides ImagingIn vitro diagnostics

Various Silica-nanoparticlesMixtures of above Gene delivery

Int J Nanomedicine. 2008 June; 3(2): 133–149

Nanoparticles & Applications in Life Sciences

NANOTECHNOLOGY

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Syngenta - Nanoemulsions in pesticide products:

– Primo MAXX® - Plant growth regulator – Used in turfgrass- prior to stress – strengthen physical structure

– Karate ® ZEON – λ-cyhalothrin (synthetic pyrethrins) - breaks open upon contact with leaves

– “Gutbuster” - Breaks open under alkaline conditions of the gut of certain insects

Precise Delivery Systems: Delivery of chemicals (Herbicides & insecticides)

Companies alliances with LG, BASF, Honeywell, Bayer, Mitsubishi, & DuPont - Plant health monitoring systems in next 10 yrs

NanotechnologyApplication in Agriculture @ Field Level

Plant health monitoring system: Devices giving early hints of pathogen/disease attack

Many more applications: Utilization of Agricultural Waste / Residues

Challenges are Plenty

Persisting CHALLENGES create newer opportunities for INNOVATION!

7Networking & Collaboration

BIOTECHNOLOGY / NANOTECHNOLOGY / INFORMATION TECHNOLOGY

PROCESS & PRODUCT

Identification Challenges

Key Factors for Innovation SuccessInfrastructure; Human Resource; Networking

INNOVATIONfor novel processes

and products

IS

HR

NW

Identify Challenges

Rural Urban

Objectives / Survey / Benefits

NECESSITY is the MOTHER of Invention

POLICY

FRAMEWORK

Regulatory Clearances

Government of KarnatakaBiotech Policy II highlights Importance of Biotech 2001; 2011

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v1.0 2001 / v2.0 2011 / v3.0 Soon

Vision Group on Biotechnology- Karnataka

Biotech Parks / Clusters for Innovationa. Bangalore Helix- BBC b. NPIC_CIF @ N2P2 in CFTRI – Mysorec. Agri BT Park in UAS-Dharwadd. Marine / Aquatic BT Park Mangaloree. Vivarium – Bidar

Biotech Centers & HR – Skills Development

a. IBAB, IABT, CHG: Higher Level b. BTFS - Medium Levelc. UHS- Bagalkot

Bio Venture Fund- 50 Crores being set up:

a. 26% (13 Crores) – GOK: 74% (37 Crores- Private)b. Identified a fund mobilizer – Agreement

Registration of BT Companies (~ 150 + TBD) Operational Guidelines / Only 2 with Power subsidy More intense efforts required

Showcasing of Biotech (National / International) BLR ITE-BIZ BLR India Nano BLR India Bio

POLICY

Bio-Nano Innovation Clusters1. Bangalore Helix – Bangalore

(- KBITS / IBAB)

2. Nutra- Phyto Pharmaceuticals – Mysore (- CFTRI)

3. Agriculture Biotech – Dharwad (- UAS- Dharwad)

4. Marine Biotech – Mangalore

(- College of Fisheries- KVAFSU)

5. Animal Biotech – Bidar

(- KVAFSU)10

GoK enabled- GoK Biotech Policy

Meeting our COMMITMENT

to create INFRASTRUCTURE

To be replaced by New Map of Karnataka

BBC(IBAB)

NPIC_CIF

(CSIR-CFTRI)

Agri BT IC_CIF(UAS-

D)

Marine BT

IC_CIF(COF-

KVAFSU)

Animal BT

IC_CIF(KVAFS

U)

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GOK – KBITS+ VGBT

+ GOI - DBT

Together Explore..

- Complementation- Technologies- Expertise- Instrumentation

- Collaboration - National / International

- Funding Agencies- State / Central / International

- Mentorship- Technical- Business Development - Legal- IP- Customs, Taxation & Excise

- Help transform Karnataka/India

KARNATAKA: Mega BioCluster For Innovation & Investment

CBF – Chuncheon, S. KoreaSDI – Scotland, UK Bio Village- MD, USA WIP

BIRACC-CAMP

OPPORTUNITIES TO INVEST / NETWORK

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Bangalore Bioinnovation Centre (BBC) A joint initiative by DBT, Govt. of India and KBITS, Dept of IT, BT and S&T, Govt. of Karnataka

1. Part of Bangalore Helix Biotech Park

2. Bangalore Helix Biotech Park (86 Acres)• Institutional Area- IBAB and CHG• Innovation Area- BBC• Industrial Area- Alexandria Biotech Park

3. Focus at BBC:• All aspects of Biotechnology (Nano Tech)

ContactDr Jitendra Kumar, Managing DirectorBangalore Bioinnovation Centre (BBC)Bangalore Helix Biotech Park Electronic City Phase I, Bangalore 560100M: +91 96866 95956 email: jkumar110@yahoo.com 4. Different focus in other innovation Centers

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BBC- Bangalore BBC- Bangalore

• 40,000 – 60,000 SFT• 25 Incubation suites : 200 to 600 SFT• Common Instrumentation facility (DBT)• Compliments others such as C-CAMP• Mammalian and Plant tissue culture• Dark room /Cold room/Utilities• Animal house/Chemical store• Library / Cafeteria / Auditorium• Meeting rooms/Conference rooms• Modular Laboratories with an option of

combining adjacent labs for bigger units• Structured as Section 8 Not-for-Profit

Company with independent andautonomous governance structure

• Academic / Business Mentorship• Promote soft-landing for companies new

to Bangalore

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BBC- Bangalore BBC- Bangalore

COMMON INSTRUMENTATION FACILITY

• Basic Lab Facilities• Small Instruments• Microscopy• Histology• Molecular Biology• Genomics• Proteomics • Small Molecule Analysis• FACS• Centrifugation• Milli-Q Filtration• Cell Culture• Bioreactors• Autoclaves• Washroom

Department of Biotechnology

“Instr

umenta

tion E

xperts

”

Explore Logistics for Bio-Manufacturing (Public & Private) in Karnataka

15http://www.richcoreindia.com/

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This is just the beginning!

Bangalore Helix Biotech Park (86 Acres)• Institutional Area- IBAB and CHG (20 Acres)• Innovation Area- BBC (10 Acres)• Industrial cluster Area- Alexandria Biotech Park (56Acres)

BIOCLUSTER – South Bangalore

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BBC - Bangalore

KVAFSUBidar

College of Fisheries - MangaloreUAS- Dharwad

CFTRI- Mysore

IC_CIFs

Innovation Clusters

OPPORTUNITIES TO INVEST & COLLABORATE

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EBQ – Edinburgh - Scotland

Genopole Campus - ParisJanssen Labs – San Diego

CBQ – Chuncheon – S. KoreaOUR BIOTECH PARKS must meet– INTERNATIONAL STANDARDS

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Bangalore South Bio Corridor - Cluster

Critical Mass

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Bangalore North Bio Corridor - Cluster

Critical Mass

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Institute for Bioinformatics and Applied Biotechnology (IBAB – BLR)

Ganit Labs - BLR

IABT - DharwadCentre for Human Genetics - BLR

Neem genome

done

Eco System: Institutions in Bangalore Helix Park

Our Determination

To build Human Resource

Institute for Agricultural Biotechnology @ UAS- DHARWAD

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Our Promise

To harness talent

First Cycle (2011 – 16) 7 Cities 9 Domains 12 Colleges02 Semesters03 Batches Finished4th Batch Internship5th Batch enrollment

Rs.10,000/- DBT Fellowship

~ 75% Placement

Next Cycle: 2016-21 A few new domains Nano Tech Stem Cells Data Management

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Bangalore India NANO

INVEST KARNATAKA 201523-25 November 2015

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For further details please contact :Principal Secretary / MD- KBITSDepartment of IT BT and S&T6th Floor, 5th Stage, MS BuildingBangalore 560001KARNATAKA- INDIA

Phone : +91– 80– 2220 -7006 / 2226 5943, Tele fax : +91-80-2272-7480, secy-itbt@karnataka.gov.in http://www.bangaloreitbt.in 

Thank You