MEDICINE - University of Pittsburgh

54
DIVISION OF DEPARTMENT OF MEDICINE ANNUAL REPORT FY20 GERIATRIC MEDICINE

Transcript of MEDICINE - University of Pittsburgh

DIVISION OF

DEPARTMENT OF MEDICINEANNUAL REPORT FY20

GERIATRICMEDICINE

ANNUAL REPORT

Message from the Chief 3

Faculty Listing 4

Clinical Activities 7

Quality Improvement Initiatives 9

Clinical Locations 14

Research Activities 16

Grants and Contracts Awarded 37

Teaching Activities 40

One-Year Bibliography 45

Acknowledgments 50

TABLE OF CONTENTS

DIVISION OF GERIATRIC MEDICINE

3

Division of Geriatric Medicine

Our mission is to enhance the health of older adults, by providing superb clinical care, training

others to do the same, and conducting research to ensure that tomorrow’s care is better than today’s.

When COVID arrived, we were well-positioned to lead key initiatives to help vulnerable older adults. We initiated eConsults and successfully transitioned our own patients to telehealth bringing visit volumes and quality metrics to pre-COVID levels by June. We provided medical management to all of UPMC’s 35 post-acute facilities, 24/7. We helped UPMC to create and deploy “swat teams” to test its SNF patients on-site, and we assisted its hospitals with difficult transfer decisions. We employed our telemedicine expertise to link the City’s EMS service to ED doctors, enabling them to test patients on-site and avoid the need for ED transport. By galva-nizing Pitt’s healthcare students, we were also able to respond to the state’s plea to help the 600 post-acute facilities in West-ern PA with concerns regarding PPE sourc-ing, testing, management, admission, and transfer decisions. In turn, the program’s success provided an opening to work with legislators to craft and unanimously pass a bill that allocated $175M to create a similar program statewide, allowing us to partner with local healthcare systems to lead it in the west. These efforts also forged allianc-es which—combined with Pitt’s expertise in virology and our own in SNF research—enabled us to respond to NIH’s requests to assist with COVID research focused on frail seniors, including trials of convalescent plasma, vaccines, and diagnostic testing. Finally, one of our faculty members, Dave Nace, was asked to join the White House Coronavirus Commission for SNF Quality and Safety.

DIVISION OF

GERIATRIC MEDICINE

With the national declines in funding, we have increasing-ly relied on innovation as our primary strategy for achiev-ing our goals. This year, although the advent of COVID-19 effectively divided the year into two parts, it also show-cased each of these aspects. Highlights are described be-low, and details are provided in the sections that follow. Clinically, prior to COVID, we enhanced our shared sav-ings program with UPMC’s Health Plan; by adding pa-tients, exceeding quality benchmarks, and improving ef-ficiency, we saved >$1 million. In addition, we built on the success of our telemedicine efforts, which had previously reduced unplanned nursing home transfers, contributed to our two successful $20 million CMS Innovation Center grants, and led UPMC Enterprises to sponsor our creation of Curavi HealthTM: in FY19, CuraviHealth acquired a New York telemedicine company; it now serves >150 nursing homes in 14 states and recently merged with 2 other com-panies to form Arkos. We also employed several initiatives to help UPMC reduce readmissions: (1) we expanded our Geriatric Trauma Service, which provides a proactive approach to >2000 older trauma patients admitted annually to UPMC Pres-byterian (PUH); propensity analyses showed that we cut readmissions by 42%. (2) Our delirium prevention (HELP) program at UPMC Shadyside continued to cut readmis-sions hospital-wide, consistent with its prior performance (JAGS 2018). (3) With radiology, we devised a new program to reinsert PEG tubes in NH patients and avoid ED visits. (4) We initiated a novel transition service for older TAVR and heart failure patients discharged to NHs. (5) With or-thopedics, we enhanced our Fracture Liaison Service (JBMR 2017) to ensure that, in addition to fracture repair, older patients receive appropriate therapy for osteopo-rosis; the service, which reduced recurrent fracture from 10% to 1.5%, is now the model for the National Osteopo-rosis Foundation, and we are working with UPMC Health

Neil Resnick, MD Chief

FACULTY

4

Department of Medicine 2020 Annual Report

Neil Resnick, MDChief, Division of Geriatric MedicineThomas Detre Professor of MedicineAssociate Director, Aging Institute of UPMC Senior Services and University of PittsburghDirector, Hartford Center of Excellence in Geriatrics

Namita S. Ahuja-Yende, MDClinical Assistant Professor of MedicineMedical Director, UPMC Heritage Shadyside Nursing CenterMedical Director, UPMC Health Plan I-SNP Program

Huai Y. Cheng, MD, MPH, MSAssociate Professor of Medicine

Becky D. Clarkson, PhDAssistant Professor of Medicine

Robert Elson, MDClinical Instructor of Medicine

Daniel E. Forman, MDProfessor of MedicineChair, Section of Geriatric Cardiology

Ramanamurthy R. Gokula, MDClinical Instructor of Medicine

Susan L. Greenspan, MDProfessor of MedicineDirector, Osteoporosis Prevention and Treatment Center

Aditi U. Gurkar, PhDAssistant Professor of Medicine

Steven M. Handler, MD, PhDAssociate Professor of Medicine, Biomedical Informatics, and Clinical & Translational ResearchAssociate Professor of RAND-University of Pittsburgh Health Institute (RUPHI)Core Faculty, Center for Critical Care NephrologyDirector of Geriatric Telemedicine ProgramsChief Medical Informatics Officer (CMIO), UPMC Community Provider Services

Joseph T. Hanlon, PharmD, MSEmeritus Professor of Medicine

Shuja Hassan, MDAssistant Professor of MedicineMedical Director, UPMC Canterbury Place

John Jochum, MDClinical Instructor of Medicine

Mary P. Kotlarczyk, PhDResearch Assistant Professor of MedicineAssociate Director, Osteoporosis Prevention and Treatment Center

Lena K. Makaroun, MD, MSAssistant Professor of MedicineCore Investigator, VA Pittsburgh Center for Health Equity Research and Promotion

Elizabeth M. Metrovich, DOClinical Assistant Professor of Medicine

David A. Nace, MD, MPHAssociate Professor of MedicineDirector of Long Term Care & Flu Programs, University of PittsburghInstitute on Aging, Medical Director

Neelesh K. Nadkarni, MD, PhDAssistant Professor of Medicine

John Naumovski, MDClinical Assistant Professor of Medicine

Anne B. Newman, MD, MPHProfessor of Medicine (Secondary Appointment)

Elizabeth A. O'Keefe, MDAssociate Professor of MedicineAssociate Director, Geriatrics Fellowship program

David A. Pasquale, DOClinical Assistant Professor of Medicine

KPG Subashan Perera, PhDProfessor of Medicine and BiostatisticsCore Co-Leader & Senior Statistician, Data Management and Analysis Core of the Pittsburgh Claude D. Pepper Older Americans Independence Center

Beth Porter, MDClinical Assistant Professor of Medicine

Jennifer A. Pruskowski, PharmDAssistant Professor of MedicineDirector, Geriatric Research and Education

Sangeeta Rana, MD, MPHAssistant Professor of Medicine

Eric G. Rodriguez, MD, MPHAssociate Professor of Medicine

Michelle I. Rossi, MD, MPHAssociate Professor of Medicine and EpidemiologyAssociate Director of Clinical Care Activities, Geriatric ResearchEducation and Clinical Center (GRECC) VA Pittsburgh Healthcare SystemDirector, Geriatric Evaluation and Management (GEM) Clinic, VA Pittsburgh Healthcare System

Fred H. Rubin, MDProfessor of MedicineChairman, Department of Medicine at UPMC Shadyside

Karen G. Scandrett, MD, MPHAssociate Professor of MedicineDirector, Geriatric Fellowship Program

Leslie Scheunemann, MD, MPHAssistant Professor of Medicine

Stasa D. Tadic, MD, MSAssociate Professor of MedicineAcademic Chief, Geriatric Medicine, UPMC MercyPhysician Leader, Supportive Services, UPMC Health Plan

Adele L. Towers, MD, MPHAssociate Professor of Medicine & PsychiatrySenior Clinical Advisor, UPMC EnterprisesDirector of Risk Adjustment, UPMC Enterprises

Shachi Tyagi, MD, MSAssistant Professor of Medicine

Adrian Visoiu, MDClinical Associate Professor of Medicine

Keisha Ward, MDClinical Assistant Professor of Medicine

Debra K. Weiner, MDProfessor of MedicineAssociate Director, Geriatric Fellowship Program

Rollin M. Wright, MD, MA, MPHAssistant Professor of MedicineChair of Education Committee, Division of Geriatric Medicine

5

Division of Geriatric Medicine

CHIEF'S MESSAGE

6

Department of Medicine 2020 Annual Report

Plan to scale it. We also continued two novel ambulatory geriatric subspecialty services: geriatric cardiology and geriatric chronic pain, and we partnered with nursing to sustain our delirium prevention rooms, both at UPMC PUH and Mercy hospitals. We also continued working with UPMC Mercy to create a Geriatric Center of Excellence; in FY20, Mercy achieved NICHE and Geriatric Emergency Depart-ment certification as well as Age-Friendly Health System recognition. Finally, we recruited a new Clinical Chief and a clinician, and we were again highly ranked by U.S. News and World Report. Educationally, we again filled our fellowship and T32 slots with excellent trainees. We substantially enhanced our rotation for medical residents, and our new geriatric pharmacist launched a widely circulated “Phast Phacts” newsletter. We also expanded and enhanced our required interdisciplinary medical school training course which now comprises >200 students from 10 healthcare disciplines; the course is led by Dr. Rollin Wright who also published her innovative hospitalist and dementia teaching modules in Annals of Internal Medicine Online. Finally, our Pepper Center provided a univer-sity-wide leadership training program for junior faculty members in aging.In research, we found that: (1) a low-intensity multifaceted educational approach can reduce in-appropriate antibiotic use by 25% in nursing homes and cut the incidence of C Diff by two-thirds (Nace, JAMA Int Med); (2) nearly 40% of patients discharged from hospital to a nursing home suffer an adverse event, the majority of which could be prevented (Handler, JAMA Int Med), (3) the state of the art approach to preventing falls among seniors at highest risk is of limited benefit (STRIDE [Greenspan, Resnick], N Engl J Med); (4) hospitals’ focus on preventing falls is misguided and should instead focus on maintaining mobility (Rubin, JAGS); (5) among incapacitated ICU patients, discus-sions often fail to include the patient’s own values and preferences (Scheunemann, JAMA Int Med); (6) by contrast with women aged 50-70, among those over age 80 who have taken a bisphosphonate for 5 years, it is more cost-effective to continue the drug for 5 years than to take a drug holiday (Greenspan, Osteop Int); (7) focusing on both nocturia and a behavioral approach to enlarge bladder capacity could provide a safer and possibly more effective approach to insomnia than drugs (Tyagi, JAGS);(8) contrary to USPSTF guidelines, screening for intimate partner violence among older women is warranted given its prevalence and impact (Makaroun, JAMA Netw Open); and (9) changing the paradigm of preclinical testing should improve the relevance of such testing for novel Alzheimer's drugs (Rizzo, Alz Dement). In addition, we continued our collaboration with Dr. Toren Finkel and UPMC’s Center of Excel-lence in the Biology of Aging, expanded our NIH-funded Center of Excellence in Long-Term Care Research, and renewed our T32 in Gerontology as well as our NIH Center of Excellence in Aging, the Pepper Center. Finally, faculty members secured new NIH funding, won research awards; contin-ued to serve on editorial boards as well as advisory boards of NIH, CDC, ACIP, AGS, and NOF, and as consultants to CMS, HEDIS and NQF, as well as the state. And Dr. Nace was appointed to the White House Coronavirus Commission for Safety and Quality in Nursing Homes.Pittsburgh VA/GRECC: After receiving a prestigious GRECC 20 years ago, our VA reallocated its geriatrics services to other service lines. In April, it decided to rethink this approach and named one of our faculty members, Steve Handler, to the newly-created position of ACOS for Geriatrics. Dr. Handler will remain a key Division faculty member, and we will partner with him to build on the considerable accomplishments of our existing GRECC faculty. In fact, our first success was the joint recruitment in May of Jennifer Pruskowski, PharmD, an outstanding geriatric pharmacist.

7

Division of Geriatric Medicine

Even excluding our VA efforts, we are responsible for thou-sands of ambulatory visits and hospital discharges, and near-ly 15,000 long term care visits at 13 different facilities. In ad-dition to our clinical volume, which is large for an academ-ic geriatric Division, our effort comprises several special fea-tures:

� Physician Excellence: 15 of our faculty are now in America’s Top Docs and/or Best Doctors in America. And, of <50 UPMC physicians (of >7500) to receive UPMC’s Award of Excellence in 2020, 3 were from our faculty.

� Vertically-Integrated Care, Across the Entire Health Care Spec-trum for thousands of our patients.

� Chronic Care Management (CCM): We were the first NCQA-certified Patient Centered Medical Home designed specifically for geriatric pa-tients (Gennari A et al. Cleveland Clin J Med 2012; 79: 359-66). We have now augmented it by creating a program to manage patients with multiple chronic conditions in compliance with the new CCM billing code. The program is based on patient goals, involves all members of the care team, and is designed to anticipate and avert problems in our most complicated patients.

� Group Visits: For >15 years, Dr. Towers has led one of the first such programs in an academic center.

� Integrated Geriatric Subspecialty Care: Consultative care is provided by fellowship-trained geriatricians, many of whom have additional training in cardiology, chronic pain, gait/mobility, sarcopenia, falls, osteoporosis, pulmonary/critical care, sleep disorders, incontinence, rheu-

We focus on pre-vention and man-

agement of the complex medical and psychosocial problems that afflict older adults.

CLINICALACTIVITIES

Geriatric faculty aspire everyday to improve the quality of life for the elderly

Photo top right

Keisha Ward, MD, brings a Lovebug Therapeutic Horse to visit patients at Asbury Heights.

Photo left

Drs. David Nace and Karen Scandrett were recognized as Long Term Care Physicians

Photo bottom right

CLINICAL

8

Department of Medicine 2020 Annual Report

matology, depression, dementia, audiology, or palliative care. DXA testing is provided by a dually-trained geriatric endocrinologist (Dr. Greenspan).

� Geriatric Pharmacists and Social Workers: Our geriatric pharmacists review medications, provide education, and counsel patients (cf: Gavini, Gennari, Ruby, Consult Pharm 2015;30:153). This service is especially important for patients recently discharged from the hospital or SNF and for those on warfarin. Our social workers serve both inpatients and outpatients. They help with care transitions, family conferences, and end of life/palliative care discussions. They also provide resources to address care deficits and financial issues, and they educate patients and families on a variety of topics including dementia and insurance coverage.

� Emergency Care. Both UPMC Magee and UPMC Mercy now screen for delirium in every older patient in the Emergency Dept., and pharmacists review the medications of every patient with a positive screening test.

� Hospitalist and Consult Services. At Shadyside, we staff a geriatrics hospitalist service and a consult service.

� HELP Program: Based on Dr. Inouye’s program and led by Dr. Rubin, this service prevents de-lirium, reduces readmissions, and saves >$7 million/yr since 2008 at UPMC Shadyside (Rubin, JAGS 2006, 2011, and 2018)

� UPMC Presbyterian (PUH) Geriatric Trauma Service. Dr. Scandrett initiated this service in 2016 to meet the needs of >2000 older patients admitted annually to our Level 1 trauma hos-pital. Readmissions were cut 42%.

� Fracture Liaison Service (UPMC PUH-Shadyside). Dr. Greenspan created this national mod-el to ensure that, in addition to surgical repair, those with a fracture are evaluated and treated for osteoporosis (JBMR 2017).

� Telemedicine Service for all of our institutionalized residents, both after hours and on week-ends.

� Teledementia service created by Dr. Rossi for VA patients and caregivers too far away to come to Pittsburgh

� Transitional Care Management/Readmission Prevention. Each of our patients is contact-ed within 48 hours of hospital discharge to review their progress, medications, unanticipated problems, and plans for medical follow-up. Uniquely, we have a similar process for our patients discharged from SNFs. In addition, for each readmission, the clinicians involved (PCP, hospitalist, NH physician, pharmacist, social worker, and/or home care) strive to identify interventions to prevent future readmissions, both at the patient and the system level.

� Advanced Heart Failure. A new unit, created at UPMC’s Canterbury SNF, is led by Drs. Hassan and Mathier and designed to reduce readmissions following discharge of patients with TAVR or advanced heart failure.

� Program for All-Inclusive Care of the Elderly (PACE). Directed by one of our adjunct faculty and working closely with the Division, this multisite program allows frail elderly to continue living at home.

� Nursing Home (NH) and Assisted Living. We provide care for hundreds of these residents, as well as training and medical leadership for more than 3 dozen facilities to improve care and reduce unnecessary admissions.

� Provision of Non-Reimbursable Services. Our readmission prevention service, an anticoag-ulation program for frail patients, Lifeline® even for those unable to pay, 55 Alive (to assess driving safety), and respite care.

9

Division of Geriatric Medicine

Our initiatives focus on each relevant setting. Some highlights include:

Ambulatory CareTelemedicine. With COVID restrictions, we have incorporated telemedicine visits into clinical prac-tice and plan to continue offering these visits to our high-risk patients next year. We also began offering eConsults in EPIC, which enables us to provide geriatric coverage to medical practices in surrounding and more remote areas. Chronic Care Management (CCM). For patients with frailty and/or multimorbidity, we develop a care plan in the context of their goals, life expectancy, and functional status. By using this informa-tion to develop an action plan and to reach out between office visits to assess progress, we qualify for CMS’ chronic care billing code. This enables us not only to defray the costs but also to provide targeted, multidisciplinary care from pharmacists, social workers, and CRNPs to additional patients, as well as same day appointments and continuity of care between care settings. These initiatives led to a 97% score on CG CAHPS. Based on our success, other departments have now begun to imple-ment the model.Transitional Care Management. In FY19, to determine whether Medicare’s new TCM billing code could enable us to further improve our transitional care, we hired a pharmacy technician to identify, track, and coordinate transitions for all of our patients discharged from a hospital, rehabilitation facility, or SNF. This year we shifted the task to our LPNs who ensure that each patient is called within two business days of discharge to address questions, unexpected problems, and any antici-pated difficulty in returning for follow-up within two weeks. The program has been well received by patients, staff, and physicians, and it won the “2019 People’s Choice” award at the UPMC PUH-SHY Quality Fair. By tracking its efficacy and cost, we hope to be able to systematize the program and disseminate it.Depression. We continue our CRNP-led depression screening and management program. Based on the PROSPECT study, which was developed by our geropsychiatrists’ (JAMA, 2004), we screen each of our patients with the PHQ-2, followed as needed by the PHQ-9. A positive score triggers the provid-er to evaluate and treat the patient according to an algorithm that we adapted with input from our geropsychiatrists. Patients are followed for 6-12 months by an interdisciplinary team that monitors response and assists with problem-solving. Annual Wellness Visits. To offer this valuable service to more patients, in FY20 we began schedul-ing patients to automatically see a CNP before or after their routine PCP visit. The focus is on pre-ventive services, immunizations, diet and exercise, and advance directives. We continue to garner top scores for preventive services across UPP. Dementia Care Assessment and Management Initiatives. Funded by HRSA’s Geriatric Workforce Enhancement Program (GWEP), we (Dr. Wright, Dr. Nace, and Ms. Jones) collaborated with Geriatric Psychiatry (Dr. Whyte) and the School of Nursing (Dr. Mathews) to develop and pilot a new dementia assessment program using CMS’ newly-approved cognitive assessment and non-face to face pro-longed service codes. We are now expanding the program by training additional providers and by

QUALITY IMPROVEMENTINITIATIVES

CLINICAL

10

Department of Medicine 2020 Annual Report

offering cognitive impairment eConsults to scale it across the UPMC Health System.

Emergency CareIn 2015, we and our colleagues in the Magee-Women’s Emergency Department became one of just two US programs selected to work with leaders from the American College of Emergency Physicians and the Society of Academic Emergency Physicians to improve care of older emergency patients. Funded by the Hartford Foundation, our first project began with development of a quality improve-ment program to enhance detection and management of delirium. Repeated QI cycles improved nurse-administered screening of older adults from 33% to >90% and the rate of physician confir-matory testing to 85%, with a positive screen triggering a pharmacist review of medications. To enhance reliability, we incorporated the tools and process into the EMR, which also enabled us to disseminate the program to UPMC Mercy. We are now developing a standardized care plan for ad-mitted patients and refining educational tools for patients and family. Follow up of patients with a positive score is underway to determine who can be safely discharged from the ED and the support required. A presentation of the MWH ED experience was accepted at SAEM conference in May 2020. A second project recently began to improve pain management for geriatric patients. The goal is to train ED physicians to provide regional anesthesia with femoral blocks for patients with hip frac-tures.

Inpatient CareMagee Acute Care and Transitions Program (ACT). Our program was based on two tenets: op-timal geriatric care requires anticipating problems and preventing them, and improved systems can help to do so. Led by Dr. Visoiu, over 8 years we identified new problems in medication recon-ciliation (Marcum et. al. J Am Geriatr Soc 2015 [2 articles]), expanded and enhanced our Geriatric Consult Service, and worked with orthopedics to improve protocols for all fracture patients. Within 2 years, we documented ≥50% reduction across the entire medical service in ALOS, falls, complications, and readmissions (cut to 10%), which we sustained for years. Unfortunately, faced with staff turnover, an unforeseen faculty shortage, and increased demand for our help on the UPMC PUH Trauma ser-vice, we had to suspend the MWH ACT although we continue to provide UPMC Magee with inpatient Geriatric consults.Delirium Reduction. Led by Dr. Visoiu, we worked with leaders in psychiatry, nursing, ED, and IT to design a Pathway to improve the approach to delirium in older patients. The goal is universal screening, prevention, and enhanced interprofessional management, from the ED to the wards. As described above, we integrated ED screening of all patients >65 years old. Unexpected departures of key faculty and UPMC’s CMIO delayed further intervention, so we switched our focus to reducing nursing documentation, partnering with UPMC’s CNO (Lorenz) and CQO (Minnier). We found that documentation could be substantially streamlined; for instance, we reduced required nurse docu-mentation for a new admission from 36 electronic screens to 8. The hope was to use the freed up time to enable enhanced screening and intervention – not only for delirium but for other problems as well. Unfortunately, the initiative was suspended owing to UPMC’s new partnership with Micro-soft and anticipated changes in the EMR. Fortunately, under Dr. Rubin’s leadership, the successful HELP program continues to reduce delirium at Shadyside on 11 wards (JAGS, 2017). In addition, under Dr. Tadic’s leadership, and with support of two grants from the Beckwith Foundation, we worked with nursing at UPMC Mercy to implement a delirium screening and prevention program for the medical service as well as a new activity room for demented patients who are at increased risk for delirium; both have been effective.Supportive Services Program. Developed in partnership with UPMC’s Health Plan and the Section of Palliative Care, early analyses proved that this program improved care and saved over $500,000/year. Based on its success at UPMC’s PUH, Dr. Tadic launched a new base at UPMC Mercy in FY14

11

Division of Geriatric Medicine

where, over the past 6 years, it has also generated a demand for consults on patients not insured by the Health Plan. Both sites are staffed by a nurse who is backed up by faculty members from geri-atrics and palliative care. By identifying and consulting proactively on high risk patients, our goal is to minimize complications, ensure a seamless post-discharge transition, and reduce readmissions.Geriatric Medicine Trauma Consult Service at PUH. We continue providing geriatric consultation for high risk patients at PUH, in partnership with general medicine. Propensity analyses by the Wolff Center in FY18 documented a 42% reduction in readmissions for such patients despite being select-ed for increased vulnerability. In FY20, we initiated a Geriatric Trauma Morbidity & Mortality confer-ence, which generated quality improvement opportunities to: (1) improve delirium management; (2) revise order sets to reduce deliriogenic prescribing (e.g., remove diphenhydramine from the platelet transfusion order set); and (3) reduce inappropriate cervical collar use in frail older adults.Fracture Liaison Service (FLS). As national pressure mounts to decrease length of stay, most frac-ture patients are now discharged without assessment or treatment of the underlying cause. With extramural funding, Dr. Greenspan designed this novel service, which increased bone density screening in such patients from 9% to 72% and appropriate medical treatment from 4% to 45%. This would have translated into an improved rating in the HEDIS measure from 1 star to 4 stars. More importantly, it was accompanied by reduction in the re-fracture rate from 10% to 1.3%. Based on these results, UPMC has supported the program which is now the model advocated by the National Osteoporosis Foundation.

Home CareLiving at Home (Dr. Rodriguez, Medical Director). This team-based preventive program collabo-rates with PCPs to provide advanced care coordination for roughly 500 high risk community-dwell-ing elderly with evidence of inadequate social support and cognitive and functional compromise. Nurses and social workers make home visits to assist with managing medications, keeping medi-cal appointments, arranging in-home and community services, and defining goals of care. Results have been excellent (Castle, Resnick. J Applied Geron-tol 2014), and participation in the program has been consistently associated with lower rates of emergency department visits, hospitalizations, and institutional-ization.

Long-Term Care (LTC)COVID-19. The Division played a critical role in COVID-19 management at LTC facilities, both within and beyond UPMC. Working with UPMC Senior Com-munities, we established a COVID-19 Command Cen-ter along with policies and processes to minimize in-fection. As of June 19, only one resident had become infected in UPMC’s 36 facilities on 21 campuses. The lack of secondary cases reassured staff of the effec-tiveness of our PPE plans and usage. Also, in collabo-ration with the Wolff Center and Senior Communities, we implemented a PCR testing program. By July, 2020, >6000 tests had been completed (2100 residents and 3900 staff) with 0.85% and 0.77% positivity rates, re-spectively. Impact beyond UPMC. The Divi-sion’s work was shared with PA’s

Drs. Rollin Wright and Keisha Ward honored for their commitment to being Long Term Care Physicians.

Photo

CLINICAL

12

Department of Medicine 2020 Annual Report

Departments of Health and Human Services, and was also used to establish national guidance for long-term care (LTC) facilities through AMDA (paltc.org/COVID-19) and the CDC. In addition, it helped create a public-private collabora-tion with the PA Depart-ment of Human Services that we were asked to lead: the Educational Support and Clinical Coaching Pro-gram for Southwest PA (ESCCP-West UPMC). ESCCP provided consultative support and facility assessment related to COVID-19 to all 600+ regional long-term care facilities. It also served as a learning opportunity for med-ical and nursing students who participated in the outreach and consulta-tions. Moreover, based on program’s success, PA House Speaker Turzai asked us to submit a similar statewide proposal. The resulting Act 24 is providing $175 million to six regional health systems. Funds will be used over 6 months for testing, onsite assessment, and advanced clinical management in the Commonwealth’s 1900 LTC facilities. UPMC and AHN are together overseeing the 600 facilities in SW and NW Pennsylvania. Reducing Unplanned Admissions. Led by Drs. Nace and Handler, in collaboration with UPMC Senior Communities, we created a comprehensive program to reduce unplanned admissions from nursing homes (NHs) to the hospital. It focuses on 4 issues: a) better understanding of patients’ care goals, b) earlier detection of deterioration, c) improved team communication, and d) use of clini-cal care pathways. The program reduced unplanned admissions across UPMC-owned NHs by 45%, from 4.9/1000 patient days in Jan 2010 to 2.7 in June 2013, with subsequent plateau. Its success led to our receiving a $19 million CMS Innovation Award (“RAVEN”) to implement and evaluate the pro-gram in 20 non-UPMC facilities. Based on success of the new program, which netted savings of $5 million (Inger, Health Affairs 2017), CMS awarded us another $20 million to sustain the intervention in the same 20 NHs, replicate it in another 20 NHs, and test a new payment model for all 40 NHs that pays both them and their practitioners to provide higher-level care on site. The RAVEN program will continue through October 2020.Telemedicine. Led by Dr. Handler, and in coordination with Curavi, in FY19 we expanded our tele-medicine service still further. Acquisition of New York’s TripleCare has enabled us to now cover >150 NHs across 14 states. In addition, we expanded our hours of coverage, from 84 to 108 hours of night and weekend coverage per week. As of July, 2020, our combined entity has conducted more than 65,000 consults resulting in >12,000 avoided hospitalizations.Teledementia. Led by Dr. Rossi, we continued our innovative VA teledementia program (JAGS 2017) and added more VA partners from across the country. Together they are utilizing national VA and CMS databases to evaluate the novel program’s health impact, as well as its effect on polypharmacy and under-prescribing. In 2017, Dr. Rossi added a new component: telesupport for those who care for these challenging patients. The program has decreased caregiver burden, and in FY20 she began expanding the intervention into patient’s homes.Dementia Care Management Initiative. Since 2011, the Division has led the Pennsylvania Demen-tia Care Partnership, which has effected a 30.1% decrease in antipsychotic use statewide. In addition, by emphasizing an interprofessional approach in our own UPMC Senior Communities facilities, we have reduced antipsychotic use across our own facilities to 14.6%, and the rate at two-thirds of our facilities is now below the state average.

Geriatric faculty and staff wearing red to raise awareness that heart disease is the #1 killer of women.

Photo

13

Division of Geriatric Medicine

Antimicrobial Stewardship. Under Dr. Nace’s leadership, and funded by AHRQ, the Division is spearheading new approaches to antimicrobial stewardship in long-term care. First, he helped to develop a national antimicrobial toolkit (https://www.ahrq.gov/nhguide/index.html). Second, he and his colleagues completed the Optimizing Antibiotic Stewardship in LTC Settings (OASIS) project, which involved 12 sites in Wisconsin and PA. Employing a systems approach, they compared antibi-otic prescribing workflows at each site. After identifying problems in communication and collabora-tion between nursing staff and prescribers as the highest priority, the team developed and imple-mented a post-prescribing review (“antibiotic timeout” [Ramly, JAGS 2020]). Third, since suspected UTI is the leading cause of inappropriate antibiotic use in the LTC setting, Dr. Nace launched the “Improving Outcomes of UTI Management (IOU)” project. As part of this study, the team developed the first evidence-based guidelines for diagnosis and treatment of uncomplicated cystitis and tested them in 25 facilities (12 intervention and 13 control sites). The intervention led to a 27% reduction in inappropriate treatment of asymptomatic bacteriuria, a 17% reduction in overall antibiotic use for UTI, and a 67% reduction in C. difficile infections, all without a change in mortality or hospitalizations (Nace et al, JAMA Intern Med 2020). The guidelines and tools have now been disseminated to all of the original control sites and to two more dissemination cohorts, reaching >50 homes across the country. Based on this work, Dr. Nace received a 2019 grant from the PA Department of Health to train nurses, prescribers and pharmacists to use the Modified Medication Appropriateness Index for Uncomplicated Cystitis (MMAI-UC), a modified version of a tool used in the IOU study. This work is important because current measures of antibiotic stewardship report utilization but not the more important aspect – appropriateness of use. Dr. Nace’s team is now working to study implementa-tion of the MMAI-UC as a quality measure with possible incorporation of the tool into the National Healthcare Safety Networks (NHSN) reporting system. For this work, Dr. Nace and his team received the 2019 ABIM/AMDA Choosing Wisely Champion award.Optimal Influenza Vaccines for Older Adults. The Division is collaborating with the Pittsburgh Vaccination Research Group to evaluate the effectiveness of different influenza vaccines in non-frail, pre-frail, and frail older adults. Led by Dr. Nace, this research is also investigating the impact of sarcopenia in vaccine response.

CLINICAL

14

Department of Medicine 2020 Annual Report

CLINICALLOCATIONS

UPMC Benedum Geriatric Center—UPMC Montefiore3459 Fifth Avenue, 4 EastPittsburgh (Oakland), PA 15213

UPMC Senior Care—UPMC ShadysideShadyside Medical Building5200 Centre Avenue, Suite 405Pittsburgh (Shadyside), PA 15232

University of Pittsburgh Osteoporosis Prevention and Treatment CenterKaufmann Medical Building3471 Fifth Avenue, Suite 1110Pittsburgh (Oakland), PA 15213

15

Division of Geriatric Medicine

RESEARCH

16

Department of Medicine 2020 Annual Report

Our faculty was again recognized for its research. More than 50 of their abstracts were accepted for presentation at annual meetings of the American Geriatrics Society, Gerontological Society of America, and AMDA. Dr. Scheunemann won DoM’s Research Day Award for Health Services/Epide-miology, Dr. Makaroun won AGS’ Presidential Poster Award for Epidemiology, Dr. Gurkar spoke at the TEDxPittsburghWomen event on chronological versus biological aging, and Dr. Nace received the 2019 ABIM/AMDA Choosing Wisely Champion award.

Division faculty also served on editorial boards and as visiting professors, committee chairs, and keynote speakers at national and international meetings. For instance, Dr. Newman is Editor of the Journal of Gerontology: Medical Sciences, and Dr. Nace is Associate Editor of JAMDA; Dr. Green-span is President of the National Osteoporosis Foundation. Drs. Greenspan and Newman served on NIA’s Board of Scientific Counselors and NIA’s External Advisory Council, respectively, while Dr. Greenspan served on NIA’s Clinical Trials Advisory Panel; and Dr. Forman served as Chairman of the American Heart Association’s Committee on Older Populations.

Current Division-led research: (1) NIH Cen-ters/Program Projects: a P30 Pepper Older American’s Independence Center (Greenspan), a T32 to train in geriatrics/gerontology (Green-span/ Finkel), a Center of Excellence in Chronic Pain (Weiner), and a Leadership K07 to create a Long-term Care Research Network (Green-span); (2) NIH R01/R56/R21s: Nitrite for HFpEF, and a modified approach to geriatric rehab (MACRO; both R01s [Forman]), PREVENTABLE (Forman, site PI), CNS mechanisms mediat-ing treatment response in overactive bladder, and brain mechanisms involved in urge incon-tinence (two R01s, Resnick), pathophysiology and behavioral therapy of nocturia (two R21s, Tyagi), CNS mechanisms underlying situational

RESEARCHACTIVITIES

Our goals are to: conduct cutting-edge research to improve the health of older adults and train the next generation of investigators to do the same. Areas of inquiry include

biology of aging, mobility/falls, frailty/sarcopenia, cardiology, chronic pain, osteoporosis, polypharmacy, incontinence, insomnia, rehabilitation, elder abuse, telemedicine, and long term care. Our funding contributed to Pitt’s being among the nation’s top recipients of NIH funding in aging.

RESEARCHBY THE NUMBERS

In FY20, the Division of Geratric Medicine received a total of $5.6m in research funding from the Public Health Service, Veterans Administration, and various societies and foundations. Research expenditures exceeded $4.9m, a slight decrease from FY19.

GRANTS & CONTRACTS AWARDEDFY20

17

Division of Geriatric Medicine

RESEARCH EXPENDITURESFY16-FY20

GRANTS & CONTRACTS AWARDEDFY20

RESEARCH

18

Department of Medicine 2020 Annual Report

urgency (R21, Clarkson), neural resilience in mobility impairment (Rosano/Hanlon), zoledronic acid for osteoporosis in institutionalized elderly (R01, Greenspan/Nace/Resnick), efficacy of denosum-ab for osteoporosis in long-term care (R01, Greenspan/Nace/Resnick), innovative approach to geri-atric osteoporosis (R01, Greenspan), a PCORI trial of home- vs. center-based cardiac rehabilitation (Forman); STRIDE, a pragmatic NIH/PCORI-funded trial to prevent injurious falls among high risk elderly (Greenspan/Resnick); R00 supplement (Gurkar); (3) CMS/CMMI-funded: RAVEN to reduce SNF transfers (Handler/Nace); (4) VA: role of hip arthritis in chronic low back pain (Weiner), devel-opment and validation of clinical prediction rules in seniors with lumbar spinal stenosis (Weiner), patient-centered vs. image-directed treatment of chronic low back pain (Weiner), a telemedicine ap-proach to improve care of community-based dementia patients (Rossi), and elder abuse in veterans (Makaroun); (5) Career Development: Dr. Nadkarni’s K23 on Alzheimer's; Dr. Scheunemann’s K08 on ICU Survivors; (6) AHRQ grants: reducing adverse drug events in nursing homes (Handler/Han-lon), improving outcomes of UTI in long-term care facilities (Nace), telemedicine to transform med-ication review for high- risk drugs in the nursing home (Handler), and two complementary grants to devise and implement a novel antibiotic stewardship intervention for nursing homes (Nace); (7) Pitt/UPMC funding: factors involved in premature and delayed aging using next generation DNA sequencing (Greenspan/Resnick); transcranial stimulation to treat urge incontinence (Clarkson), and medical marijuana and chronic pain in older adult (Nadkarni/Weiner).

Collaborations with non-Division PIs include: (1) P01/P50s: Alzheimer’s (ADRC, Lopez/Rodriguez, Na-dkarni), Molecular Transducers of Physical Activity Centers [MotrPAC, Forman/Jakicik]); sarcopenia mechanisms (SOMMA, Forman/ Newman/Nadkarni); mechanisms of stochastic damage of aging (Robbins/Perera), new approaches to urinary tract dysfunction due to spinal cord injury (Kanai/Per-era); biomechanical, biological and behavioral phenotypes (Weiner/Sowa); (2) R01s: a task-specific approach to improving gait and mobility (Brach/Perera), osteoporosis risk in smokers (Greenspan/ Bon), activating patients with osteoporosis (Saag/Greenspan), aging’s impact on urothelial function (Resnick/Birder), impact of obesity on body composition, gait, and function in older adults (Cham/ Perera), assessing the impact of improved vitamin D status on vascular health and metabolic syn-drome risk (Rajakumar/Greenspan), Reducing Sedentary Behavior RESET BP (Kline/Perera); inves-tigating exercise-associated gains in neurocognition (Forman/Erickson); metformin for pulmonary hypertension (Forman/Simon) (3) R56/R21/R24/R18s: biomarkers to predict lung function decline in physiologically normal smokers (Perera/Sciurba), establishment of the research infrastructure to facilitate analyses of Medicare Advantage plans (Gurwitz/Greenspan), dissemination of a diabetes prevention program in seniors (Venditti/Greenspan), and a PCORI-funded trial to examine exercise for fracture prevention in community elderly (Greenspan/McTigue) and another to devise and eval-uate a novel group exercise program to reduce falls in assisted living facilities (Brach/Perera); (4) K01: to devise a falls risk monitoring algorithm using a data mining technique (Boyce/Perera); (5) 3 VA Merit Reviews: patterns, determinants, and consequences among veterans receiving opiates from VA and non-VA sources (Gellad/Hanlon), improving safety and appropriateness of prescribing for demented veterans who receive drugs within and outside of the VA (Hanlon/Gellad), and cu-mulative CNS drug dosage and serious fall injuries (Hanlon/Thorpe) (6) Pitt/UPMC Funding: Toolkit for nursing home care (Handler/Harris), immune fingerprinting signatures in predicting successful aging (Greenspan/Perera/De Vallejo).

Our research training grants support junior faculty, fellows, and medical students. Our T32, which was recently refunded, now includes collaboration with the Aging Institute and an initiative with Dr. Jonassaint, Vice Chair of Diversity and Inclusion, to recruit URM trainees. Dr. Studenski’s former NIH K07 Leadership Award created an enduring Concentration in Aging Research for Pitt’s Clinical Research Training Program. Our Pepper Center incorporates an REC core, led by Dr. Resnick, which trains junior faculty in leadership and administration. And, Drs. Nace and Wright collaborated on the university’s HRSA-funded Geriatric Education Center (GWEP).

19

Division of Geriatric Medicine

Faculty Research Interests and Activities

Neil Resnick, MD Division ChiefA Professor of Medicine and Division Chief, Dr. Resnick focuses his research on the pathophysiol-ogy and therapy of geriatric syndromes. He serves as PI and Co-I for NIH-funded multidisciplinary studies of urinary incontinence that incorporate physiologic, neuroimaging, clinical, pharmacologi-cal and behavioral research aims. In addition, he serves as PI for two foundation-funded initiatives to develop system-based approaches to prevent, detect, and treat delirium in hospitalized patients. He is also a Co-Investigator on Dr. Greenspan’s research in geriatric osteoporosis, including her R01-funded studies in the nursing home and a PCORI-funded study of falls. Finally, he co-directs the Research and Career Development Core of the NIH-funded Pittsburgh Older Americans Inde-pendence Center, and he leads the Older Adult Research Network for the Pittsburgh Clinical and Translational Science Institute (CTSI).

Study Sections • Ad Hoc Reviewer, Division of Research Grants, NIA/NIH, 1983-present• Ad Hoc Reviewer, Gerontology and Geriatrics, NIA/NIH, 1988-present

Advisory Committee Memberships and Leadership Positions • Member, Scientific Advisory Board, Simon Foundation, 1984-present• Member, Abstract Review Committee, American Geriatrics Society, 1985-present• Member, Scientific Advisory Board, American Federation of Aging Research,

1989-present• Reviewer, Gerontological Society of America, 1989-present• Member, Advisory Committee, Alliance for Aging Research, 1991-present• Member, Advisory Committee, Geriatric Research Education and Clinical Center (GRECC),

Pittsburgh VA Health System, 1999-current • Co-Director, Pennsylvania American Geriatrics Society CME course: Clinical Update in

Geriatric Medicine, 2000-present• Member, Board of Directors, American Geriatrics Society, Pennsylvania/West Virginia

AGS Chapter, 2000-present• Member, Council of State Affiliates, American Geriatrics Society, 2003-present• Advisor, CMS/Medicare Innovation Advisors Program, 2014-present• Member, Editorial Board, Current Geriatrics Reports, 2014-present• Co-Chair, Council of State Affiliates Representative, American Geriatrics Society,

2018-present• Member, Board of Directors, American Geriatrics Society, 2018-present

Professional Affiliations and Society Memberships • Member, Gerontological Society of America, 1981-present• Member, Urodynamics Society, 1982-present• Member, American Urological Association (Affiliate Member), 1985-present• Member, Governing Board, Simon Foundation, 1986-present• Member, Long Term Care Committee, University of Pittsburgh, 1999-present• Member, National Mentoring Program, American Geriatrics Society, 2005-present• Member, Board of Directors, Pittsburgh Regional Health Initiative (PRHI), 2012-present• Member, Board of Directors, Jewish Healthcare Foundation, 2012-present

Editorships • Member, Editorial Board, Current Geriatrics Reports (Springer), 2014-present

Major Lectureships and Seminars • Speaker, AHRQ/PCORI, Improving Care for Women with UI, New York, NY, 2019• Member, Invited Panel, American College of Physician, “Meet the Professor”,

RESEARCH

20

Department of Medicine 2020 Annual Report

1990-present• Invited Lecturer, Pennsylvania American Geriatrics Society, Update in Geriatric Medicine,

Pittsburgh, Pennsylvania, 2000-presentHonors and Awards

• Best Doctors in America, Best Doctors Inc, 1992-present• Top Doctors in America, Castle Connolly’s Guide to America’s Top Physicians,

2000-present• Best Doctors, Pittsburgh Magazine, 2002-present

Huai Y. Cheng, MD, MPH, MSTrained in basic, clinical, and epidemiological research, Dr. Cheng is now interested in conducting medical education research in geriatrics curriculum development and evaluation and systematic re-view. Additionally, he is also interested in decision making and EBM in value- and preference-based prescribing and de-prescribing when treating elderly patients multiple co-existing conditions and complex needs. Dr. Cheng also conducts research in innovative geriatric practice models.

Professional Affiliations and Society Memberships • Member, American Geriatric Society, 2000-present• Member, American Medical Director Association, 2001-present• Member, Gerontology Society of America, 2011-present• Member, Alliance for Academic Internal Medicine, 2014-present• Member, The Association for Medical Education in Europe, 2018-present

Becky D. Clarkson, PhDOriginally trained as a medical physicist, Dr. Clarkson uses her experience of developing clinical tests and diagnostic tools to integrate brain imaging and bladder provocation to understand and treat bladder dysfunction related to higher control mechanisms. Her NIH-funded research focuses on environmental triggers of urinary leakage and using MRI to characterize the central neural control system of the continence mechanism. She is currently using the findings from this research as the basis for developing therapies for urgency incontinence which focus on bladder control, specifically behavioral therapies, and brain stimulation methods.

Advisory Committee Memberships and Leadership Positions • Co-Chair, Brain Bladder Research and Imaging Network, 2016-present

Professional Affiliations and Society Memberships • Member, Institute for Physics and Engineering in Medicine, 2004-present• Member, International Continence Society, 2007-present

Major Lectureships and Seminars • Invited Speaker, Neurogenic Bladder Research Group (NBRG) Meeting, 2019• Presenter, Swiss Continence Foundation, 7th Annual International Neuro-Urology

Meeting, Zürich, Switzerland, January 2020

Daniel E. Forman, MDA Professor of Medicine, Dr. Forman is dually trained in geriatrics and cardiology. He holds appoint-ments in both Divisions at UPMC as well as in both the Geriatrics Research Education and Clinical Center (GRECC) and the Cardiology Division at the Pittsburgh VA. With NIH funding, he is studying the benefit of nitrate capsules for fatigue and function in older adults with heart failure and pre-served ejection fraction. In two other NIH projects, he is studying the impact of exercise on skeletal muscle gene transcription (Molecular Transducers of Physical Activity in Humans [MoTrPAC]) and the impact of exercise training on cognition (Investigating Gains in Neurocognition in an Interven-tion Trial of Exercise [IGNITE]). At the VA, he is comparing the impact of different training regimens

21

Division of Geriatric Medicine

(strength, aerobic, and inspiratory muscle training) on skeletal muscle morphology, gene expres-sion, and functional capacity. He is also researching the utility of prehabilitation in frail elderly prior to abdominal and cardiothoracic surgery. Finally, Dr. Forman is funded by PCORI to devise novel strategies to improve cardiac rehabilitation, especially methods to improve enrollment, adherence, and value for complex, older cardiovascular patients.

Study Sections • Grant Reviewer, NIH/NHLBI, 2019• Scientific Reviewer, NHLBI UG3/U24 study section, 2019• Abstract Reviewer, American Heart Association National Meeting, Philadelphia, PA, 2019-

2020• Abstract Reviewer, American College of Cardiology National Meeting, New Orleans, LA,

2019-2020• Program Committee Leader, American Association for Cardiovascular and Pulmonary

Rehabilitation National Meeting, Portland, OR, 2019-2020• Scientific Reviewer, VA Rehabilitation Research and Development Service, 2019-2020

Advisory Committee Memberships and Leadership Positions • Inaugural Chair and Member, Geriatric Cardiology Section, American College of

Cardiology, 2009-present• Chair, Advocacy Workgroup, Geriatric Cardiology Section, American College of

Cardiology, 2014-present• Chair, International Workgroup, Geriatric Cardiology Section, American College of

Cardiology, 2014-present• Member, Council on Clinical Cardiology (CLCD) – Council Leadership Committee,

2015-present• Chair, Council on Clinical Cardiology, Older Populations Committee, American Heart

Association, 2016-present• Member, Council on Clinical Cardiology, Cardio Respiratory Fitness Registry,

2017-present• Member, Healthy Lifestyle Institute, University of Pittsburgh, 2017-present• Member, Program Committee, American College of Cardiovascular and Pulmonary

Rehabilitation, 2018-2021• Chair, cardiovascular track AACVR annual meeting (3-yr appointment), American

Association of Cardiovascular and Pulmonary Rehabilitation, Chicago, IL, 2018-present• Member, Tenured Faculty Promotions and Appointments Committee, University of

Pittsburgh, 2018-present• Member, Older Populations, American Heart Association, 2019-2020• Advisory Panel, Veterans Affairs, Cooperative Studies Program Coordinating Center, 2020• Member, Prevention Section, American College of Cardiology, 2020

Professional Affiliations and Society Memberships • Member, Data Safety and Monitoring Board, REHAB-HF, National Institute of Aging,

2014-present• Committee Member, Cholesterol Guideline Committee (American Geriatric Society

representative), Guideline committee, American College of Cardiology/American Heart Association, 2017-2019

• Faculty Member, F1000 Prime, Geriatric Cardiology, 2017-present• Member, Medical Subspecialties Section, American Geriatrics Society, New York, New

York, 2017-present• Member, Research Committee, American Geriatric Society, 2018-2021• Member, Executive Committee, Pittsburgh Claude D. Pepper Older Americans

Independence Center, University of Pittsburgh, Pittsburgh, PA, 2018-present• Member, American Geriatrics Society, 2019-2020

RESEARCH

22

Department of Medicine 2020 Annual Report

• Fellow, American College of Cardiology, 2020• Fellow, American Heart Association, 2020• Member, American Association of Cardiovascular and Pulmonary Rehabilitation, 2020

Editorships • Guest Editor, Clinics of Geriatric Medicine, 2020• Reviewer, Journal of the American Geriatrics Society, 2020• Editorial Board, Journal of Cardiopulmonary Rehabilitation and Prevention, 2016-present• Member, Journal of the American Geriatrics Society, Cardiology, 2016-present• Editorial Board, The Journal of Gerontology: Medical Sciences, 2017-present• Guest Editor, Circulation, 2017-present• Guest Editor, Journal of the American College of Cardiology, 2018-present

Major Lectureships and Seminars • Invited Participant, NIA: A Gerocentric Approach to Heart Failure with Preserved Ejection

Fraction in Older Adults, Bethesda, MD, 2019• Invited Speaker and Program Chair, NIA U13 conference, Washington, DC, 2019• Invited Speaker and Chair of Cardiology Panel, Annual Update in Geriatric Medicine,

University of Pittsburgh, Pittsburgh, PA, 2019• Invited Speaker, Lifestyle Institute, University of Pittsburgh, Pittsburgh, PA, 2019• Invited Speaker, Aging and Cancer Brainstorming Workshop, University of Pittsburgh,

Pittsburgh, PA, 2019• Invited Speaker, 15th International Congress of Update in Cardiology and Cardiovascular

Surgery (UCCVS), The American Heart Association, Antalya, Turkey, 2019• Invited Speaker, NHLBI Cardiovascular and Pulmonary Rehabilitation Investigators

Meeting, Bethesda, MD, 2019• Invited Speaker, Mid-Atlantic Capital Cardiology Symposium, Washington, DC, 2019• Invited Speaker (3 presentations), American Association of Cardiovascular and

Pulmonary Rehabilitation, Annual Meeting, Portland, OR, 2019• Keynote Speaker, American Geriatrics Society, Annual Meeting, Portland, OR, 2019• Meyers Visiting Professor of Geriatric Medicine, University of Massachusetts School of

Medicine, Worchester, MA, 2019• Visiting Professor, University of Vermont School of Medicine, Burlington, VT, 2019• Invited Speaker, Lifespan Cardiology Grand Rounds, Brown University, Providence, RI,

2020• Invited Speaker, Annual Update in Geriatric Medicine, University of Pittsburgh,

Pittsburgh, PA, 2020• Invited Speaker, GRECC, VAPHS, Pittsburgh, PA, 2020• Invited Speaker, NHLBI Workshop, Bethesda, MD, 2020• Invited Speaker, Barnes Jewish Hospital, Cardiovascular Grand Rounds, 2020 (cancelled

due to COVID-19)

Susan L. Greenspan, MDDirector of UPMC’s Osteoporosis Prevention and Treatment Center and Director of Bone Health at Magee Women’s Hospital, Dr. Greenspan is dually-trained in Geriatrics and in Endocrinology. Her research focuses on geriatric osteoporosis, including its pathophysiology, evaluation, and treat-ment. Her current R01s focus on osteoporosis in institutionalized elderly, including new treatment modalities and new assessments of bone strength. In addition, she is PI of our NIH-funded Pepper Center, our NIH T32 Pitt Integrated Clinical and Geroscience Research Training Program, and has a K07 that has developed a research registry and network for research in senior communities. A former member of NIH/NIA’s Board of Scientific Counselors, she now serves on NIA’s Clinical Trial Advisory Panel. She is also President of the National Osteoporosis Foundation and a member of its Board of Trustees.

23

Division of Geriatric Medicine

Advisory Committee Memberships and Leadership Positions

• Member, NIH/NIA Clinical Trials Advisory Program (CTAP), 2014-present

• Team Member, FNIH Sarcopenia Project, 2017-present

• Co-Chair, National Bone Health Alliance, 2018-present

Professional Affiliations and Society Memberships • Member, Steering Committee, American Society

of Bone and Mineral Research Secondary Fracture Prevention, 2018-present

• Member, Steering Committee, Fracture Liaison Service Key Outcome Measures, 2018-present

Editorships • Editorial Board, Journal of Gerontology, Medical Sciences, 1999-present• Editorial Board, National Osteoporosis Foundation, 2004-present

Major Lectureships and Seminars • Presenter, National Osteoporosis Foundation, Annual Meeting, May 2020 (cancelled due

to COVID-19)• Presenter, Endocrine Society Annual Meeting, June 2020 (cancelled due to COVID-19)• Presenter, Endocrine Fellows Foundation ASBMR Annual Conference, September 2020

(cancelled due to COVID-19)

Aditi U. Gurkar, PhDDr. Gurkar’s interest is in understanding the biology of aging and age-related diseases. Her NIH-fund-ed research focuses on identifying the signaling mechanisms that drive aging in response to endog-enous DNA damage. By defining these molecular mechanism(s), she hopes to identify novel thera-peutic targets that can be exploited to extend healthspan.

Advisory Committee Memberships and Leadership Positions • Co-Preceptor, Grant-Writing Workshop, Department of Medicine, University of

Pittsburgh, 2019Editorships

• Reviewer, eLife, 2019• Reviewer, Mechanisms of Aging and Development, 2019• Reviewer, PLoS One, 2019• Reviewer, DNA Repair, 2014-2019

Major Lectureships and Seminars • American Heart Association, American Heart Association Scientific Session, Philadelphia,

PA, November 2019 • TEDx, Pittsburgh, PA, 2019• Laidlaw Scholars, University of Oxford, Oxford, England, 2019• International Student Congress of (bio)Medical Sciences, Netherlands, June 2020

Professional Affiliations and Society Memberships • Member, American Aging Association, 2019-present, • Member, Society for Redox Biology and Medicine, 2019-present

Study Sections • Grant Reviewer, Aging Institute-Hillman Cancer Center Pilot Funds, 2019

Dr. Susan Greenapan discusses bone health with residents of Asbury Heights

Photo

RESEARCH

24

Department of Medicine 2020 Annual Report

• Judge, Smiddy Undergraduate Research Award (Florida International University), 2020• Judging Committee, Department of Medicine Annual Research Day, 2020• Grant Reviewer, The Dutch Research Council (NCO), 2020

Steven M. Handler, MD, PhDAn Associate Professor of Geriatrics, Dr. Handler also holds appointments in Biomedical Informat-ics and in Clinical and Translational Research. In addition to his role as Director of Geriatric Tele-medicine Programs, he serves as Medical Director for Telemedicine and Health Information for the RAVEN (Reduce AVoidable hospitalization using Evidence-based interventions for Nursing facilities in Western Pennsylvania) CMS Innovation Award. A practicing geriatrician, Dr. Handler’s primary research focuses on medication and patient safety, telemedicine, and clinical decision support sys-tems for older adults in the post-acute and long-term care setting.

Advisory Committee Memberships and Leadership Positions • Member, Pennsylvania Medical Directors Association (PMDA), 2004-present• Steering Committee Member, Long-Term Care Research Network, American Medical

Directors Association (AMDA), 2006-present• Technical Expert, Westat Research Corporation, “Developing a Patient Safety Culture

Instrument for Nursing Home Use,” 2006-present• Member, Health Information Technology (HIT) Subcommittee, American Medical

Directors Association (AMDA), 2008-present• Developer, Institute for Healthcare Improvement (IHI), Trigger Tool for Measuring

Adverse Drug Events in the Nursing Home, 2009-present• Member, Telehealth Advisory Committee, University of Pittsburgh/UPMC, 2012-present• Member, University of Pittsburgh/UPMC, Beckwith Clinical Transformation Program,

2012-present• Safety Expert Panelist, Center for Medicare and Medicaid Services’ (CMS) Innovation

Center, F-329 (Unnecessary Drugs) Guidance for State Surveyors Redesign Committee, 2012-present

• Member, Center for Medicare and Medicaid Services’ (CMS) Innovation Center, Enhanced Care and Coordination Provider (ECCP) Medical Director Council, 2013-present

• Member, University of Pittsburgh Graduate School of Public Health, Executive Leadership Committee, Center for Pharmaceutical Policy and Prescribing (CP3), 2013-present

• Member, PatientOrderSets.com, Long-Term Care Expert Advisory Group, 2014-present• Technical Expert and Physician Lead, Physician and Patient Safety, Centers for Medicare

and Medicaid Services (CMS)Raising Awareness for Reducing Adverse Events in Nursing Homes Campaign, 2014-present

• Member, Executive Committee for Quality Prescribing Campaign, AMDA/Society for Post-Acute and Long-Term Care, 2015-present

• Member, PA Dept. of Health, Taskforce on Quality Improvement in Nursing Home Regulation and Oversight, 2015-present

• Member, University of Pittsburgh/UPMC, Telehealth Operations Committee, 2015-present

• Member, National Quality Foundation (NQF), Framework Development to Support Measure Development for Telehealth, 2016-present

• Matter Expert, West Health Institute, Subject telemedicine and co-author of Implementing Telehealth in Post-Acute and Long-Term Care Settings (PALTC), 2019-present

• Member, AMDA, PA House of Delegates, 2019-present• Technical Expert/Advisory Panel, Agency for Healthcare Research and Quality (AHRQ),

Patient Safety Network, 2020-2025• Member, University of Pittsburgh/UPMC, Surgical Hip Femur Facture Treatment (SHFFT)

25

Division of Geriatric Medicine

Postoperative GroupProfessional Affiliations and Society Memberships

• Member, American Medical Informatics Association, 1998-present• Member, American Geriatrics Society, 2000-present• Member, Society for Post-Acute and Long-Term Medicine (AMDA), 2002-present• Member, Improvement Science Research Network, 2010-present• Member, Southwestern Pennsylvania Partnership for Aging (SWPPA), 2010-present• Member, American Telemedicine Association (ATA), 2014-present• Member, Pennsylvania Medical Society, 2014-present• Member, Allegheny Medical Society, 2014-present• Member, Pennsylvania Geriatrics Society, Western Division, 2016-present• Member, Pennsylvania Medical Society, eHealth and Health IT Task Force, 2016-present

Editorships • Reviewer, The American Journal of Geriatric Pharmacotherapy, 2003-present• Reviewer, The Journal of the American Medical Directors Association, 2006-present• Reviewer, The Journal of the American Geriatrics Society, 2006-present• Reviewer, Pharmacoepidemiology and Drug Safety, 2007-present• Reviewer, The Journal of the American Medical Informatics Association, 2008-present• Reviewer, SpringerPlus, 2013-present• Reviewer, Nephrology Dialysis Transplantation, 2014-present• Reviewer, Health Affairs, 2017-present

Major Lectureships and Seminars • Invited Speaker, Elder Care, Elder Care Symposium, Williamsport, PA, 2019• Invited Speaker, UPMC St. Margaret, Geriatric Medicine Grand Rounds, Pittsburgh, PA,

2019• Invited Speaker, LeadingAge/CAST, LeadingAge/CAST, Baltimore, MD, 2019• Invited Speaker, Real Time, Annual Summit, Baltimore, MD, 2019• Invited Speaker (2 presentations), American Academy of Home Care Medicine Annual

Meeting, Chicago, IL, 2019• Invited Speaker (3 presentations), Society for Post-Acute and Long-Term Care Medicine

(AMDA) Annual Symposium, Atlanta, GA, 2019• Poster Presentation, Research Day, Department of Medicine, University of Pittsburgh,

Pittsburgh, PA, 2019• Invited Speaker, Department of Biomedical Informatics Colloquium Series, University of

Pittsburgh, Pittsburgh, PA, 2020• Invited Speaker, National Consortium of Telehealth Resource Centers, Penn State

Project, ECHO COVID-19 Series, Webinar, 2020• Invited Speaker, AMDA Webinar Series, 2020

Joseph T. Hanlon, PharmD, MSAn Emeritus Professor of Medicine, Dr. Hanlon is also a geriatric pharmacist and health scientist with both the Center for Health Equity Research and Promotion (CHERP) and the Geriatric Research Education and Clinical Center (GRECC) at the Pittsburgh VA. His research focuses on three themes: 1) drug-related problems, 2) racial disparities in medication use, and 3) drug-induced geriatric syn-dromes. He serves as a Co-I and Consultant on a number of federally funded grants and on the editorial boards of four journals.

Shuja Hassan, MDDr. Hassan provides primary care and consultative services to older adults at UPMC Senior Care-Shadyside. He is board certified in Internal Medicine and Geriatrics. Dr. Hassan is also the Medical

RESEARCH

26

Department of Medicine 2020 Annual Report

Director at UPMC Canterbury Place, a long-term care facility.Advisory Committee Memberships and Leadership Positions

• Co-Director, Pennsylvania/W. Virginia American Geriatrics Society Annual Conference, Clinical Update in Geriatric Medicine, 2000-present

Professional Affiliations and Society Memberships • Member, AMDA, 2001-present• Member, Pennsylvania Geriatrics Society, 2004-present

Major Lectureships and Seminars • Presenter, Update in Geriatric Medicine, PA Geriatrics Society, Pittsburgh, PA, March

2020Honors and Awards

• Best Doctors, Pittsburgh Magazine, 2016-present

Mary P. Kotlarczyk, PhDDr. Kotlarczyk is a Research Assistant Professor of Medicine and Associate Director of the Osteo-porosis Prevention and Treatment Center. Dr. Kotlarczyk is also a current Scholar of the Pittsburgh Claude D. Pepper Older Americans Independence Center. Her research focuses musculoskeletal health and physical function in older adults, particularly those residing in long-term care communi-ties.

Advisory Committee Memberships and Leadership Positions • Co-facilitator, Pittsburgh Claude D. Pepper Center Leadership and Cultural Coaching

Workshop Series for Junior Faculty, 2017-present• Member, Early Career Faculty Workgroup for the Pepper Older Americans Independence

Center (OAIC) Coordinating Center, 2018-2020Professional Affiliations and Society Memberships

• Member, Pittsburgh Claude D. Pepper Center Long-term Care Workgroup, 2015-present• Member, American Geriatrics Society, 2015-present• Member, Gerontological Society of America, 2015-present• Member, American Society for Bone and Mineral Research, 2015-present• Member, American Geriatrics Society, Osteoporosis Special Interest Group, 2016-present• Member, American Geriatrics Society, Junior Faculty Research Special Interest Group,

2017-present• Member, Pittsburgh Claude D. Pepper Center Muscle Aging Workgroup, 2019-present

Editorships • Scholar, Journal of the American Geriatrics Society Junior Reviewer program, 2017-2019• Ad Hoc Reviewer, Journal of the American Geriatrics Society, 2017-present

Lena K. Makaroun, MD, MSAs a geriatrics health services researcher at the VA Pittsburgh Center for Health Equity Research and Promotion and a Pepper Scholar at the University of Pittsburgh Claude D. Pepper Older American Independence Center, Dr. Makaroun studies social influences (“determinants”) of health for older adults, with a particular focus on inter-personal violence, elder abuse, trauma and caregiving. She has an additional interest in studying firearm ownership and safety in older adults with dementia. Dr. Makaroun’s work focuses on improving detection of elder abuse and developing evidence-based, multi-disciplinary interventions to improve outcomes for this population.

Study Sections • Ad Hoc Reviewer, VA Center for Health Equity Research and Promotion Competitive Pilot

Award Program, 2019-present

27

Division of Geriatric Medicine

Advisory Committee Memberships and Leadership Positions • Member, Geriatric Division Education Committee, University of Pittsburgh, 2019-present• Member, PA Department of Human Services, Department of Health COVID Education

Support Clinical Coaching Program, April 2020-present Professional Affiliations and Society Memberships

• Member, American Geriatrics Society, 2009-present• Member, American Medical Association, member, 2013-present• Member, Gerontological Society of America, 2017-present• Member, Board of Directors, American Geriatrics Society, 2018-present• Member, PA Geriatrics Society, Western Division, 2018-present• Member, Investment Committee, American Geriatrics Society, 2019-present• Member, Engagement Task Force, American Geriatrics Society, 2020-present• Member, PA Medical Society, 2020-present

Editorships • Ad Hoc Reviewer, JAMA Internal Medicine, 2019-present• Ad Hoc Reviewer, Journal of the American Geriatrics Society, 2019-present

Major Lectureships and Seminars • Presenter, UPMC Mercy Hospital Medicine Grand Rounds, Pittsburgh, PA, November

2019 • Presenter, National VA Emergency Medicine Monthly Call, Virtual, January 2020 • Presenter, Update in Clinical Geriatrics Review Course, University of Pittsburgh Medical

Center/American Geriatrics Society, Pittsburgh, PA, March 2020• Presenter, Futures Without Violence National Conference, 2020 (cancelled due to

COVID-19)• Presenter, American Geriatrics Society Annual Scientific Meeting, 2020 (cancelled due to

COVID-19)

David A. Nace, MD, MPHDr. Nace is an Associate Professor of Medicine whose research focuses primarily on infectious disease in long-term care, particularly antimicro-bial stewardship, vaccine preventable diseases, and outbreak prevention and response. He is the PI of the Improving Outcomes of UTI Manage-ment in LTC Study, an AHRQ funded dissemination and implementation project. As part of the IOU project Dr. Nace’s team developed guidelines for the diagnosis and treatment of uncomplicated cystitis in nursing home residents and is testing the implementation of these guidelines in a na-tional cohort of nursing homes. Dr. Nace’s team received the AMDA/ABIM Choosing Wisely Campaign Award in March 2019 for this work. Dr. Nace is now leading work to develop a potential antibiotic stewardship quality measure that can be used by facilities and physicians. This would be the first quality measure that describes appropriateness of antibiotic prescribing as opposed to the existing crude utilization measures. This pilot work is being funded by the PA Department of Health. Dr. Nace is Co-PI on a CD-funded study evaluating the humoral and cellular response to the influenza vaccine in a cohort of adults 50 years and older by frailty status. He is also conducting a Pepper Center-funded pilot study to evaluate the impact of sarcopenia on humoral and cellular response among older adults. He serves as Co-Medical Director for our recently-renewed $39 million CMS Innovations Award project (RAVEN), which has devel-oped innovative approaches to reducing unplanned hospital transfers from nursing homes. Finally, he collaborates with other Division researchers on a variety of NIH, AHRQ, and foundation-fund-ed studies of older adults regarding infection control, osteoporosis, adverse drug events, palliative

Beyond working to develop a national antimicrobial toolkit, Dr. David Nace was instrumental in national efforts to improve COVID safety measures in SNFs.

Photo

RESEARCH

28

Department of Medicine 2020 Annual Report

care, interprofessional training, and quality assessment and improvement.

Advisory Committee Memberships and Leadership Positions • Chair, PMDA Public Policy Committee, 1997-present• Chair, UPMC Senior Communities PT Committee, 2006-Present• Chair, Pennsylvania Dementia Care Partnership, 2012-present• Vice Chair, AMDA Public Policy Committee, 2015-present• Vice President, AMDA – The Society of Post-Acute and LTC Medicine, 2018-2019• Chair, Public Policy Committee, AMDA – The Society of Post-Acute & Long-Term Care

Medicine, 2019-2020• President-Elect, AMDA – The Society of Post-Acute and LTC Medicine, 2019-2020• Member, UPMC, COVID-19 Leadership Team - Post-Acute & Long-Term Care,

2019-present• Member, A Secretary of Health’s Advisory Health Board, 2019-present• Member, CDC Healthcare Infection Control Practices Advisory Committee (HICPAC),

Long-Term Care Advisory Group, 2019-present• President, 2020-2021, AMDA – The Society of Post-Acute and LTC Medicine, 2020-2021• Advisory Lead, Pennsylvania Department of Human Services COVID-19 Educational

Support and Clinical Coaching Program (ESCCP) West-UPMC Lead, 2020-present• Member, AMDA COVID-19 Task Force, 2020-present

Professional Affiliations and Society Memberships • Member, UPMC Senior Communities Board of Directors, 2004-Present• Member, UPMC Influenza Task Force, 2004-Present• Member, UPMC Health System Infection Control Expert Work Group, 2009-Present• Member, UPMC Health System PT Committee, 2012-Present• Member, Department of Medicine, Clinical Directors Council, 2012-Present

Editorships • Abstract Reviewer, GSA, 1999-Present• Reviewer, American Journal of Geriatric Pharmacotherapy, 2004-Present• Reviewer, Infection Control and Hospital Epidemiology, 2004-Present• Reviewer, Vaccine, 2010-Present• Reviewer, Annals of Internal Medicine, 2010-Present• Associate Editor, JAMDA, 2018-present

Major Lectureships and Seminars • Invited Speaker, Florida State University, Advances in Post-Acute & Long-Term Care

Symposium, Tallahassee, FL, August 2019• Presenter, UPMC Susquehanna Williamsport, Eldercare Symposium, Williamsport, PA.,

September 2019• Invited Speaker, ID Week 2019, Washington, DC, October 2019• Invited Speaker, PMDA Annual Symposium, Hershey, PA, October 2019• Presenter, Public Policy Spotlight, FMDA Best Care Practices in the PALTC Continuum,

Orlando, FL, October 2019• Presenter, Philadelphia Department of Health, Healthcare Associated Infections Meeting,

Philadelphia, PA, October 2019• Presenter, RAVEN Leadership Day, Pittsburgh, PA, October 2019• Presenter, Department of Medicine Grand Rounds, University of Pittsburgh, Pittsburgh,

PA, January 2020 • Presenter, Update in Geriatric Medicine, PA Geriatrics Society, Pittsburgh, PA, March

2020• Invited Speaker, AMDA Annual Symposium, Virtual National Conference, April 2020• Presenter, University of Pittsburgh Medical Center, Medicine Grand Rounds, Pittsburgh,

29

Division of Geriatric Medicine

PA, March 2020 • Presenter, UPMC Shadyside, Medicine Grand Rounds, April 2020

Honors and Awards • Best Doctors, Pittsburgh Magazine, 2009-present• Best Doctors in America, Best Doctors, Inc, 2009-present• POLST Champion, PA POLST Coalition, 2010-present• Appointed/Honor, PA Governors Long-Term Care Council, 2017-present• Appointed, PA Secretary of Health, Advisory Health Board, PA Department of Health,

2019-present• Choosing Wisely Campaign Champion 2019 for Impact of the IOU Study on Improving

UTI Management in PALTC, AMDA/ABIM, 2019• Appointed, Coronavirus Commission for Safety and Quality in Nursing Homes, MITRE,

2020

Neelesh K. Nadkarni, MD, PhDAn Assistant Professor of Medicine and of Neurology at the School of Medicine, Dr. Nadkarni is a Principal Investigator of the study that examines the influence of Alzheimer’s disease and cerebral small-vessel disease on walking, thinking, and cognitive-motor interactions in cognitively normal mobility unimpaired older adults. He is also a PI on two pilot studies, one that examines the effect of cannabis on gait and cognition in older adults with chronic pain, and another on the relationship between cardiac amyloidosis and cerebral amyloidosis in healthy older adults. He is also co-investi-gator at the Alzheimer’s Disease Research Center involved in several studies in Alzheimer’s disease and actively collaborates with faculty in Neurology, Psychiatry, and Radiology in the School of Med-icine, in the School of Rehabilitation Sciences, and in the Graduate School of Public Health at the University of Pittsburgh.

Study Sections • Reviewer, Alzheimer’s Association International Conference, 2020, • Reviewer, Human Amyloid Imaging Annual International Conference, 2020

Advisory Committee Memberships and Leadership Positions • Member, UPMC Shadyside, 2018-present

Professional Affiliations and Society Memberships • Member, Royal College of Physicians and Surgeons of Canada, 2009-present• Member, American Geriatrics Society, 2018-present• Member, International Society to Advance Alzheimer’s Research and Treatment

(ISTAART), 2018-presentEditorships

• Ad hoc reviewer, Neurology, 2004-present• Ad hoc reviewer, Journal of the American Geriatrics Society, 2005-present• Member, Journal of Gerontology and Medical Sciences, 2012-present• Ad hoc reviewer, Alzheimer’s Research & Therapy, 2017-present• Ad hoc reviewer, Journal of Alzheimer’s Disease, 2019-present

Major Lectureships and Seminars • Presenter, Alzheimer’s Association International Conference, Los Angeles, CA, 2019• Presenter, Human Amyloid Imaging, 2019 Annual Conference, Miami Beach, FL, 2019

John Naumovski, MDDr. Naumovski developed a Geriatric/Post Acute and Long Term Care Rotation for the Family Medi-

RESEARCH

30

Department of Medicine 2020 Annual Report

cine residents at Charles Morris Nursing and Rehabilitation. They learn how to manage these types of patients, to become members of the Interdisciplinary Team, and to communicate with each of the involved health care professionals (RN/PT/OT/ST/SW).

Advisory Committee Memberships and Leadership Positions • Member, Quality Assurance and Performance Improvement, 2019-present• Member, Task Force, Question writing, ABIM, Geriatrics Section, 2019-present

Professional Affiliations and Society Memberships • Member, American Geriatrics Society, 2013-present• Member, AMDA, 2014-present

Honors and Awards • Best Doctors, Pittsburgh Magazine, 2019-2020

Anne B. Newman, MD, MPHDr. Newman is the Distinguished Professor and Chair of the Department of Epidemiology, with a secondary appointment as Professor of Medicine in Geriatrics. A member of NIH/NIA’s National Ad-visory Council on Aging, she is Principal Investigator for several large population studies and clinical trials and also serves as Director of the Center for Aging and Population Health at the Graduate School of Public Health. In addition, she collaborates with Dr. Greenspan as Co-PI of our Pepper Center, with Dr. Hanlon in the Health ABC Study, and with Dr. Nadkarni on the LIFE Study and the ENRGISE Study. Her research focuses on the factors associated with disability and healthy aging.

Advisory Committee Memberships and Leadership Positions • Member, Advisory Board, NIH/NIA Baltimore Longitudinal Study of Aging (BLSA),

2005-present• Member, Scientific Advisory Board, The Irish Longitudinal Study of Aging (TILDA),

2009-present• Member, External Advisory Committee, ALLHAT (Antihypertensive and Lipid-Lowering

Treatment to Prevent Heart Attack Trial), 2011-present• Member, External Advisory Committee, KURE (Korean Urban Rural Elderly) Study,

2012-present• Member, National Advisory Council on Aging (NACA), National Institute on Aging,

2014-presentEditorships

• Editorial Board, Journal of Aging and Health, 2010-present• Editor-in-Chief, Journal of Gerontology: Medical Science, 2016-present

Elizabeth A. O’Keefe, MDDr. O’Keefe is an Associate Professor and Clinician-Educator with experience in many fields of In-ternal Medicine and Geriatrics derived from years of medical practice in the United Kingdom and South Africa. She has several publications relating to functional bowel disease in the elderly and has served as a reviewer for Journal of the American Geriatrics Society.

Advisory Committee Memberships and Leadership Positions • Chair, VA VISN 4 Dementia Committee, 2019-present• Member, VA VISN 4 RECICE Committee, 2020

Major Lectureships and Seminars • Presenter, GRECC Core Geriatric Lecture Series, VA Pittsburgh Healthcare System,

Pittsburgh, PA, September 2019 • Presenter, Update in Internal Medicine Conference, UPMC, Pittsburgh, PA, October 2019 • Presenter, Healthcare Disparities in Adults with Intellectual Disabilities and Dementia

31

Division of Geriatric Medicine

Panel, American Academy of Developmental Medicine and Dentistry Annual Meeting, June 2020

Honors and Awards • 2020 Excellence in Patient Experience Award, University of Pittsburgh Medical Center,

2020• Best Doctors, Pittsburgh Magazine, 2013-present

David A. Pasquale, DODr. Pasquale provides geriatric primary care and consultative services at the Benedum Geriatric Center located in UPMC Montefiore Hospital.

Advisory Committee Memberships and Leadership Positions • Member, University of Pittsburgh, Geriatric Tract Residency Committee, 2020• Member, University of Pittsburgh, Geriatric Education Committee, 2020

Professional Affiliations and Society Memberships • Member, American Geriatric Society, 2020• Member, American Osteopathic Association, 2020

Honors and Awards • Best Doctors, Pittsburgh Magazine, 2016-present

KPG Subashan Perera, PhDDr. Perera is a Professor of Medicine and Biostatistics with special interest in clinical trials, aging, time series analysis, item response theory, data mining, and predictive modeling. His work has in-volved estimating criteria for clinically meaningful change in physical performance measures of the elderly, examining their association with future outcomes using large data sets, and using item response theory to analyze rating scales used in elderly populations. Dr. Perera also co-leads the Data Management, Analysis, and Informatics Core of our Pepper Center, in addition to serving as co-investigator for multiple grants funded by the NIH, AHRQ, and within and outside of the Division.

Study Section • Member, Urology and Nephrology Clinical Small Business Applications Special Emphasis

Panel, NIDDK, 2018-present• Abstract Reviewer, GSA Annual Scientific Meeting, April 2020 • Member, Patient-Centered Outcomes Research Institute COVID-19 Merit Review Panel,

June 2020 Professional Affiliations and Society Memberships

• Member, External Data and Safety Monitoring Board: Mechanistic Approach to Preventing Atrophy and Restoring Function in Older Adults Trial, 2014-present

• Member, Data and Safety Monitoring Board: Long-term effects of weight loss and supplemental protein on physical function, 2016-present

• Member, Data and Safety Monitoring Board: Sedentary Time and Aging Research (STAR) Program Project, 2017-present

• Member, Data and Safety Monitoring Board: Hip Muscle Power, Lateral Balance Function, and Falls in Aging, 2018-present

Eric G. Rodriguez, MD, MPHDr. Rodriguez is an Associate Professor of Medicine who serves as a Co-Investigator on grants relat-ed to the study of Alzheimer’s disease.

Advisory Committee Memberships and Leadership Positions • Member, NIH Data and Safety Monitoring, Mindfulness, Education, and Exercise for

RESEARCH

32

Department of Medicine 2020 Annual Report

Cognitive Function study, 2016-presentProfessional Affiliations and Society Memberships

• Rater, McMaster Online Rating of Evidence, 2014-presentHonors and Awards

• Best Doctors, Pittsburgh Magazine, 2014-present• Best Doctors in America, Best Doctors, Inc., 2014-present

Michelle I. Rossi, MD, MPHDr. Rossi’s research focuses on appropriate medication use in older adults, chronic pain in old-er adults, and development and evaluation of new models of care in older adults (i.e., innovative models of dementia care and driving safety assessment). Her teaching activities include a variety of clinical, didactic, and mentoring interactions with medical students, residents, and fellows, as well as teaching non-physician clinician trainees (nurse practitioner, physician assistant, psychology, pharmacy, speech therapy, occupational therapy, physical therapy, social work, speech therapy, au-diology) in geriatric medicine topics. Dr. Rossi is the current Associate Director for Clinical Care with the GRECC of the VA Pittsburgh Healthcare System. She is the Director of the Geriatric Evaluation and Management (GEM) Clinic at the VA Pittsburgh Healthcare System, which is an interdisciplinary outpatient consultative clinic that provides frail older veterans with comprehensive geriatric assess-ment. She also directs the VA Dementia Clinic and the VA TeleDementia Clinic, which provide care to veterans with dementia and support to their families over the course of their illness. In addition, Dr. Rossi is Medical Director of the VA Geriatric Driving Safety Clinic, which uses an interdisciplinary team to assess driving safety in veterans with cognitive decline.

Advisory Committee Memberships and Leadership Positions • Chair, VA Pittsburgh Healthcare System, VISN 4 Dementia Committee, 2019-present

Professional Affiliations and Society Memberships • Committee Member, VAPHS IRB, 2017-present• Member, VA Pittsburgh Healthcare System, VISN 4 RECICE Committee, 2020

Major Lectureships and Seminars • Lecturer, GRECC Core Geriatric Lecture Series, VA Pittsburgh Healthcare System,

Pittsburgh, PA, September 2019 • Lecturer, 2019 Update in Internal Medicine Conference, University of Pittsburgh Medical

Center, Pittsburgh, PA, October 2019 • Lecturer, Healthcare Disparities in Adults with Intellectual Disabilities and Dementia

Panel, American Academy of Developmental Medicine and Dentistry Annual meeting, June 2020

Honors and Awards • Chief of Staff Clinical Excellence Award, VA Pittsburgh Healthcare System, 2019

Fred H. Rubin, MDA Professor of Medicine, Dr. Rubin’s research has focused on evaluating the adaptability, sustain-ability, and impact of Dr. Sharon Inouye’s Hospital Elder Life Program (HELP). He has shown that it is as effective at preventing delirium at UPMC Shadyside, a large community-based hospital, as it was in the academic setting in which it was first developed and that it can decrease readmissions. By demonstrating both its efficacy and cost-savings, he has convinced hospital management to incor-porate the program into its annual budget.

Study Sections • Grant Reviewer, Beckwith Foundation, 1998-present• Grant reviewer, Shadyside Hospital Foundation, 2019-present

33

Division of Geriatric Medicine

Advisory Committee Memberships and Leadership Positions • Chair, Clinical Faculty Appointments and Promotions Committee, Department of

Medicine, UPSOM, 1999-present• Member, American Geriatrics Society Co-Care HELP, 2019-present• Member, Planning Committee, UPMC and PA American Geriatrics Society, Update in

Geriatric Medicine, 2019-present• Member, Planning Committee, Update in Internal Medicine, UPMC, 2019-present• Moderator, Medicine Grand Rounds, UPMC Shadyside, 2019-present

Editorships • Reviewer, JAMA Surgery, 2019• Reviewer, Archives of Gerontology and Geriatrics, 2019

Major Lectureships and Seminars • Invited Lecturer, Annual International Hospital Elder Life Program Conference, 2019• Lecturer, Update in Internal Medicine, UPMC, Pittsburgh, PA, October 2019 • Lecturer, Urology Grand Rounds, University of Pittsburgh School of Medicine, Pittsburgh,

PA, December 2019 • Lecturer, Medicine Grand Rounds, UPMC Shadyside, Pittsburgh, PA, January 2020 • Lecturer, Medicine Grand Rounds, UPMC, Pittsburgh, PA, January 2020 • Lecturer, Update in Geriatric Medicine, UPMC and PA Geriatrics Society, Pittsburgh, PA,

March 2020 • Lecturer, Geriatric Medicine Spanish Society, Albacete, Spain,

April 2020 (cancelled due to Covid-19) • Lecturer, Medicine Grand Rounds, UPMC Shadyside, Pittsburgh,

PA, April 2020 Honors and Awards

• Top Doctors in America, Castle Connolly’s Guide to America’s Top Physicians, 1992-present

• Best Doctors in America, Best Doctors, Inc., 1996-present• Best Doctors, Pittsburgh Magazine, 2017-present• Physician Excellence Award, University of Pittsburgh Medical

Center, 2020

Leslie P. Scheunemann, MD, MPHAn Assistant Professor of Medicine with dual training in geriatrics and in pulmonary/critical care, Dr. Scheunemann receives support as a Pepper KL2 Scholar through the Geriatric Division’s NIA Pepper Grant. Her research focuses on developing and testing transitional care interventions to improve health, functioning, and quality of life among older adults who survive critical illness and their family caregivers.

Advisory Committee Memberships and Leadership Positions • Member, Ethics and Conflicts of Interest Committee, American Thoracic Society,

2015-present• Director, Geriatrics Area of Concentration, University of Pittsburgh, 2016-present• Member, Occupational Therapy Advisory Committee, Department of Occupational

Therapy, University of Pittsburgh, 2019-2020• Director, University of Pittsburgh Medical Center, Trauma Consult Service, 2020-present

Professional Affiliations and Society Memberships • Member, American Geriatrics Society, 2009-present• Member, American Thoracic Society, 2009-present• Member, Aging and Geriatrics Special Interest Committee, American Thoracic Society,

2017-present

Dr. Rubin co-presented "Geriatric Medicine Year in Review" in January as part of the Department of Medicine Grand Rounds Series.

Photo

RESEARCH

34

Department of Medicine 2020 Annual Report

• Member, Junior Faculty Research Group, American Geriatrics Society, 2017-presentEditorships

• Ad Hoc Reviewer, Critical Care Medicine, 2010-present• Ad Hoc Reviewer, American Journal of Geriatric Psychiatry, 2018-present• Ad Hoc Reviewer, Annals of Internal Medicine, 2018-present• Ad Hoc Reviewer, Journal of Pain and Symptom Management, 2019-present• Ad Hoc Reviewer, Annals of the American Thoracic Society, 2020

Major Lectureships and Seminars • Poster Presenter, American Geriatrics Society Annual Meeting, Annual Meeting, Portland,

OR, 2019• Invited Presenter, Claude D. Pepper Older Adult Independence Center, Annual Meeting,

Hi Impact Publication Session, April 2020Honors and Awards

• Health Services / Epidemiology Research Award, University of Pittsburgh, Department of Medicine Research Day, Pittsburgh, PA, 2019

• Top Reviewer 2019, Annals of Internal Medicine, 2019

Stasa D. Tadic, MD, MSAn Associate Professor of Medicine, Dr. Tadic has remained involved in the study of geriatric urinary incontinence. Formerly supported by an NIA K23 Career Development Award, he is a member of the Geriatric Continence Research team (Drs. Resnick, Griffiths, and Clarkson). Although now more focused in the clinical arena, he continues to play a role in the group’s efforts.

Advisory Committee Memberships and Leadership Positions • Academic Chief, Geriatric Medicine, UPMC Mercy, 2015-present• Team Member and Co-Author, Beckwith Institute QI project Delirium Progressive Medical

Unit, 2016-present• Team Member and Co-author, Beckwith Institute QI project Delirium Dementia Room,

2016-presentProfessional Affiliations and Society Memberships

• Member, American Geriatrics Society, 2004-present• Member, American Delirium Society, 2018-present

Adele L. Towers, MD, MPHDr. Towers’s research interests are the study of healthcare financing and dementia prevention and treatment.

Study Sections • Member, AHRQ HSQR, 2017-present

Advisory Committee Memberships and Leadership Positions • Co-Chair, Allegheny County Medical Society Annual Fundraising Gala, 2014-present• President Elect, Allegheny County Medical Society, 2018-2019• Member, Ursuline Support Services, Board of Directors, 2018-present• Member, UPMC Health Plan P&T Committee, 2018-present• Member, Pennsylvania Health Care Cost Containment Council (PHC4), 2018-present• President, Allegheny County Medical Society, 2019-2020• Member, AHIMA Governance Task Force, 2019-present• Chair, Allegheny County Medical Society, 2020

Major Lectureships and Seminars • Chair and Panel, RISE, RISE West Summit, San Diego, CA, September 2019

35

Division of Geriatric Medicine

• Speaker, The National Association of ACO’s, NAACOS Webinar, October 2019 • Panel, HEDIS & QI, HEDIS & QI Summit, Miami, FL, October 2019• Panel, RISE, RISE Risk Adjustment Forum, Scottsdale, AZ, November 2019• Presenter, Healthcare Payments Innovations, Phoenix, AZ, February 2020 • Presenter, Health Fidelity, Upstream Risk Adjustment: Better Care Plans & Revenue

Capture Live Webinar, March 2020 Honors and Awards

• Best Doctors, Pittsburgh Magazine, 2016-2019

Shachi Tyagi, MD, MSAn Assistant Professor of Medicine, Dr. Tyagi is supported by an NIH-R21 Grant. Her research inter-ests include nocturia and geriatric insomnia, including their causes, treatment, and impact, both on each other and on the risk of falls.

Keisha Ward, MDDr. Ward provides geriatric primary care and consultative services at the Benedum Geriatric Center.

Professional Affiliations and Society Memberships• Member, American Geriatric Society, 2017-present• Member, Long Term Care Committee, Divison of Geriatrics, 2017-present

Debra K. Weiner, MDA Professor of Medicine with training in geriatrics, rheumatology, and acupuncture, Dr. Weiner re-searches chronic pain. She is PI of two VA Merit Review studies: 1) a multisite pilot study designed to improve management of chronic low back pain (CLBP) in older adults and 2) a multisite pro-spective cohort study to ascertain predictors of outcome in veterans undergoing decompressive laminectomy for lumbar spinal stenosis. She is PI (along with Dr. Neelesh Nadkarni) of a Pepper Center-funded pilot project evaluating the impact of medical marijuana on mobility and cognitive function in older adults. She also collaborates on NIH-funded studies that evaluate the contribution of hip osteoarthritis to pain and function in older adults with CLBP and that develop pain education programs for pre-professional students. Finally, she is Co-Director of the University of Pittsburgh’s NIDA-funded Center of Excellence in Pain Education.

Study Sections • Ad Hoc Reviewer, Grant Applications, NIH, 2013-present

Advisory Committee Memberships and Leadership Positions • Member, VAPHS Pain Committee, 2009-present• Member, American Chronic Pain Association, 2011-present• Associate Director, UPMC Geriatric Medicine Fellowship, 2014-present• Acting Associate Director, Education and Evaluation – VAPHS GRECC, 2018-present• Member, UPMC Division of Geriatric Medicine Education Committee, 2019-present

Professional Affiliations and Society Memberships • Member, American Geriatrics Society, 1989-present • Member, Gerontological Society of America, 1992-present• Member, American College of Physicians, 1992-present • Member, International Association for the Study of Pain, 1997-present • Member, American Pain Society, 1998-present• Member, American Academy of Pain Medicine, 1999-present• Member, Editorial Board, Pain Medicine, 2000-present• Member, American Academy of Medical Acupuncture, 2001-present• Fellow, American College of Physicians, 2013-present

RESEARCH

36

Department of Medicine 2020 Annual Report

• Member, American Medical Association, 2019-presentEditorships

• Senior Editor, Pain Medicine, 2011-presentMajor Lectureships and Seminars

• Presenter, Cornell University, Translational Research Institute on Pain in Late Life, Webinar presentation, July 2019

Honors and Awards • Chief of Staff Clinical Excellence Award, VA Pittsburgh Healthcare System, 2019

Rollin M. Wright, MD, MA, MPHAn Assistant Professor of Medicine, Dr. Wright’s interests as a clinician educator include curriculum development and evaluation in geriatric medicine, education research, advanced dementia, inter-professional education, terminal decline, and skilled and long-term care. Her education research is funded by a HRSA Geriatric Workforce Enhancement Program (GWEP) grant.

Advisory Committee Memberships and Leadership Positions • Assistant Chair, American Medical Directors Association Annual Program Planning

Committee, 2014-present• Project Director, HRSA Geriatric Workforce Enhancement Program Project 3 (Advanced

Dementia Communication Competency), 2015-2020• Course Director, Interprofessional Geriatrics Week, 2015-present• Chair, Awards Committee, Pennsylvania Geriatrics Society-Western Division,

2016-PresentMajor Lectureships and Seminars

• Speaker, Pennsylvania Geriatrics Society-Western Division, Annual Fall Program, Pittsburgh, PA, October 2019

• Invited Lecturer, Center for Bioethics and Health Law Ethics Consortium, University of Pittsburgh, Pittsburgh, PA, December 2019

• Invited Lecturer, Pennsylvania Geriatrics Society-Western Division, Annual Geriatrics Update, Pittsburgh, PA, March 2020

Honors and Awards • Best Doctors, Pittsburgh Magazine, 2016-2019

37

Division of Geriatric Medicine

July 1, 2019 to June 30, 2020

GRANTS AND CONTRACTSAWARDED

PUBLIC HEALTH SERVICE

INVESTIGATOR TITLE AGENCYANNUALDIRECTCOSTS

ANNUALINDIRECT

COSTSClarkson, Becky Investigation of Brain Mechanisms Involved in

Situational Urgency IncontinenceNIA $53,578 $30,138

Forman, Daniel Investigating Gains in Neurocognition in an Inter-vention Trial of Exercise

NIA $11,890 $6,724

Forman, Daniel Modified Application of Cardiac Rehabilitation for Older Adults (MACRO)

NIA $853,369 $153,563

Forman, Daniel A Phase II Trial of Metformin for Pulmonary Hyper-tension in Heart Failure with Preserved Ejection Fraction

NIA $3,251 $1,837

Forman, Daniel Nitrite Therapy to Improve Mitochondrial Energet-ics and Physical Activity in Older Adults

NIA $261,503 $83,425

Forman, Daniel Pittsburgh Older Americans Independence Center NIA $102,651 $55,432

Forman, Daniel Study of Muscle, Mobility and Aging (SOMMA) NIA/California Pacific Medical Center

$73,117 $41,312

Forman, Daniel Study of Muscle Mobility and Aging Additional Measures

NIA/California Pacific Medical Center

$21,354 $12,065

Forman, Daniel Molecular Transducers of Physical Activity Clinical Centers

NIAMS $48,864 $27,608

Greenspan, Susan Autoimmunity and Emphysema and Risk of Osteo-porosis in Smokers

NHLBI $13,924 $7,519

Greenspan, Susan Innovative Approach to Geriatric Osteoporosis NIA $206,393 $89,262

Greenspan, Susan Innovative Approach to Geriatric Osteoporosis NIA $264,162 $0

Greenspan, Susan Long-Term Care Research Network NIA $81,273 $6,502

Greenspan, Susan Maintenance of Skeletal Integrity in Frail Elders - Phase 2

NIA $375,743 $199,671

Greenspan, Susan Pitt Integrated Clinical and Geroscience Research Training Program

NIA $283,809 $19,552

Greenspan, Susan Pittsburgh Older Americans Independence Center NIA $94,953 $36,896

Greenspan, Susan Sustaining Skeletal Health in Frail Elderly NIA $467,010 $258,986

Greenspan, Susan Sustaining Skeletal Health in Frail Elderly (Supple-ment)

NIA $126,460 $68,288

Greenspan, Susan Prevention of Fractures in Patients with Parkin-son’s Disease

NIA/California Pacific Medical Center

$14,053 $7,939

Greenspan, Susan TOPAZ: Trial of Parkinsons and Zoledronic Acid NIA/California Pacific Medical Center

$177,170 $53,151

GRANTS

38

Department of Medicine 2020 Annual Report

PUBLIC HEALTH SERVICE

INVESTIGATOR TITLE AGENCYANNUALDIRECTCOSTS

ANNUALINDIRECT

COSTSGreenspan, Susan Advancing Geriatrics Infrastructure and Network

Growth (AGING) InitiativeNIA/University of Massachusetts

$5,015 $2,830

Handler, Steven M. Developing and Testing an Evidence-Based Toolkit for Nursing Home Care of Residents with Obesity

AHRQ/Magee Womens Re-search Institute and Foundation

$2,554 $1,443

Handler, Steven M. Reducing High-Risk Geriatric Polypharmacy via EHR Nudges

NIA/RAND $11,560 $6,530

Hanlon, Joseph T. Pittsburgh Older Americans Independence Center PESC

NIA $96,974 $52,366

Nace, David Improving Outcomes of UTI in LTC Facilities: The IOU Study

AHRQ $109,463 $39,554

Nace, David Pittsburgh Older Americans Independence Center RC1

NIA $67,206 $36,291

Nadkarni, Neelesh Neurodegeneration in Aging Down Syndrome (NiAD): A Longitudinal Study of Cognition and Biomarkers of Alzheimer’s Disease

NIA $7,075 $3,821

Nadkarni, Neelesh The Aging Brain and the Cognition - Mobility Inter-face in Clinically Normal Older Adults

NIA $142,110 $11,321

Perera, KPG Subashan Pittsburgh Older Americans Independence Center DMAC

NIA $29,019 $15,670

Perera, KPG Subashan Restoring Central Motor Control to Improve Com-munity Mobility of Older Adults

NIA $22,575 $12,755

Perera, KPG Subashan Task Specific Timing and Coordination Exercises to Improve Mobility in Older Adults

NIA $17,586 $9,496

Perera, KPG Subashan Instrumental Screening for Dysphagia by Com-bining High-Resolution Cervical Auscultation with Advanced Data Analysis Tools to Identify Silent Dysphagia and Silent Aspiration

NICHD $14,937 $8,440

Perera, KPG Subashan Effect of Reducing Sedentary Behavior on Blood Pressure

NHLBI $23,008 $13,000

Perera, KPG Subashan Effect of Reducing Sedentary Behavior on Sleep and Cardiovascular Health

NHLBI $11,424 $6,455

Resnick, Neil M. University of Pittsburgh Clinical and Translational Science Institute

NCATS $55,526 $31,372

Resnick, Neil M. Further Enhancing Treatment of Urgency Inconti-nence

NIA $164,626 $82,898

Resnick, Neil M. Investigation of Brain Mechanisms involved in Urgency Urinary Incontinence

NIA $424,981 $240,115

Resnick, Neil M. Pittsburgh Older Americans Independence Center RCDC

NIA $219,497 $17,560

Rodriguez, Eric G. Alzheimer’s Disease Research Center-Core A NIA $15,055 $8,130

Rodriguez, Eric G. Alzheimer’s Disease Research Center-Core A NIA $30,721 $17,357

Scheunemann, Leslie TeleRecovery: Engaging Stakeholders to Adapt and Pilot Test a Scalable Transitional Rehabilitation Intervention for Older, Rural ICU Survivors

AHRQ $137,296 $10,984

Tyagi, Shachi Impact of Behavioral Treatment of Insomnia on Nighttime Urine Production

NIA $124,658 $70,432

Weiner, Debra K. Chronic Back Pain in Older Adults: The Role of Co-Existing Hip Impairments

NIA/University of Delaware

$4,180 $2,362

Weiner, Debra K. HEALing LB3P: Profiling Biomechanical, Biological and Behavioral phenotypes

NIAMS $1,232 $696

39

Division of Geriatric Medicine

PUBLIC HEALTH SERVICE

INVESTIGATOR TITLE AGENCYANNUALDIRECTCOSTS

ANNUALINDIRECT

COSTSWright, Rollin Geriatrics Workforce Enhancement Program HRSA $35,710 $2,857

TOTAL PUBLIC HEALTH SERVICE $5,308,512 $1,864,601

VETERANS ADMINISTRATION

INVESTIGATOR TITLE AGENCYANNUALDIRECTCOSTS

ANNUALINDIRECT

COSTSForman, Daniel Kostra - IPA Home Based Cardiac Rehabilitation

for Rural VeteransVAPHS $70,181 $0

Forman, Daniel Kellar IPA - Home Based Cardiac Rehabilitation for Rural Veterans

VAMC $40,706 $0

Hanlon, Joseph T. Factors and Outcomes Associated with Inappropri-ate Prescribing of Phosphodiesterase-5-Inhibitors for Pulmonary Hypertension

VA HSR&D $14,600

Perera, KPG Subashan IPA Subashan Perera USDVA $11,461 $0

Weiner, Debra K. Patient-Centered versus Imaging-Directed Care for Older Veterans with Chronic LBP

USDVA $23,645 $0

TOTAL VETERANS ADMINISTRATION $160,593 $0

SOCIETY AND FOUNDATIONS

INVESTIGATOR TITLE AGENCYANNUALDIRECTCOSTS

ANNUALINDIRECT

COSTSClarkson, Becky Investigation of the Effect of Transcranial Magnet-

ic Stimulation on the BladderAging Institute of UPMC

$49,908 $0

Greenspan, Susan Integrating Patient-Centered Exercise Coaching into Primary Care to Reduce Fragility Fracture

PCORI/Penn State

$24,998 $9,999

Greenspan, Susan MyHealthAge: Immune Fingerprinting Signatures in Predicting Successful Aging

Aging Institute of UPMC

$80,273 $0

TOTAL SOCIETY AND FOUNDATIONS $155,179 $9,999

PUBLIC HEALTH SERVICE $5,308,512 $1,864,601VETERANS ADMINISTRATION $160,593 $0SOCIETY AND FOUNDATIONS $155,179 $9,999

TOTAL $5,624,284 $1,874,600

TEACHING

40

Department of Medicine 2020 Annual Report

TEACHINGACTIVITIES

Medical StudentsLed by Dr. Wright, we teach an innovative and required week-long inter-professional geriatrics course for >200 students from the schools of medicine (MS-3), nursing, dentistry, pharmacy, and allied health (OT, PT, Speech, Social Work, Nutrition/Dietetics, Audiology, and PAs). Evaluation shows improved knowledge, attitudes, and skills in geriatric medicine and team-based practices. In addi-tion, Drs. Scheunemann and Resnick direct a novel Geriatrics Area of Concentration, which enables medical students to “major” in geriatrics (12 in FY20). In FY20, Dr. Wright mentored 2 medical stu-dents; 1 received the 2020 David C. Martin award and was invited to give 2 poster presentations at national conferences. Finally, we sponsor scholarly projects for 3-7 students/year, many of whom are funded by our T32.

Medical ResidentsAll residents devote 6 weeks to geriatrics training in the clinic, home, hospital, and nursing home settings. In addition, we offer an innovative Geriatrics Track that enables 4-9 residents to “major” in geriatrics in which they base their continuity clinic in geriatrics and also care for panels of home-bound patients. We also offer 4 advanced geriatrics rotations which, in FY20, attracted 3 track res-idents and 1 non-Track resident. Several of these innovations have been featured at national AGS meetings, including the “Roadmap,” milestones, and pharmacology QI projects as well as a new curriculum to teach residents how to communicate and work with patients and families living with dementia. In addition, Dr. Wright helped mentor 1 track resident and 1 non-Track resident for their education research projects.

Geriatric Medicine FellowshipIn FY20, under Dr. Scandrett’s leadership, we graduated 4 excellent fellows. Each submitted ab-stracts accepted for presentation at AGS, AMDA, and DOM’s Research Day, and two published ar-ticles. Two are continuing in academic geriatric medicine positions, one began an endocrinology fellowship, and one accepted a J1 waiver position as a geriatric hospitalist at a community hospital. Three excellent new fellows matched for FY21, and we are developing a new initiative to recruit more fellows from our own residency program.

Continuing Medical Education (CME)Recognized by a national award from AGS, our annual CME course again attracted 400 attendees from >20 states. Dr. Greenspan continues to teach programs on osteoporosis which she helped to

In addition to the research training described above, Division faculty members teach trainees at every level, from high school student to practicing physician. We also teach advanced practice pro-

viders and trainees in pharmacy, nursing, psychology, chaplaincy, physical/occupational therapy, and social work.

41

Division of Geriatric Medicine

create for the American Academy of Family Medicine, ISCD, and the National Osteoporosis Founda-tion. Several faculty led “Meet the Professor” sessions at national meetings (e.g., ACP, AGS).

OtherWe continue to train both Physician Assistant and CRNP students in acute care geriatrics, as well as participating in the University of Pittsburgh Health Scholars Academy. This highly competitive—and highly rated—statewide summer program on aging is comprised of 25 elite high school students from throughout Pennsylvania are selected to participate each year.

Additionally, our faculty author chapters on aging for major textbooks, including Cecil’s Medicine (Resnick; Greenspan), UpToDate (Weiner), Braunwald’s The Heart (Forman), and DiPiro’s Pharmaco-therapy (Hanlon). Division faculty have also developed national geriatric curricula for surgical sub-specialties, including ENT, urology, and gynecology.

TEACHING

42

Department of Medicine 2020 Annual Report

Clinical Fellows* indicates departing fellow

*Aaiza Aamer, MD, MSMedical School: Hacettepe University, TurkeyResidency: Lincoln Hospital, New York, NYCurrent Position: Barnabus Health Medical Group—Geri Primary Care, Bayonne, NJ

*Ilia Bernstein, BMBSMedical School: University of LimerickResidency: Jewish Hospital of CincinnatiCurrent Position: Endocrinology Fellow, University of Nebraska

Anita Chandra, MDMedical School: St. George’s University School of MedicineResidency: Allegheny General HospitalCurrent Position: Allegheny General Hospital

*Ravneet Singh Sandhu, MDMedical School: Saba UniversityResidency: MedStar Health Internal Medicine, Baltimore, MDCurrent Position: Indiana Regional Medical Center, Indiana, PA

43

Division of Geriatric Medicine

Fellow Activities

Aaiza Aamer, MD, MS Publications

• Aamer A, Bernstein I, Sandhu R, Naumovski J. Reducing unnecessary antibiotics for bilateral cellulitis, Journal of the American Medical Directors Association, Vol. 21, Issue 3, B8. Published in issue: March 2020

• Baagar KA, Khan F, Zirie M, Darwish S, Mohammed AK, Aamer A, Shady A, Salama A, Hussein A, Adly H, Gul W. Prevalence and Predictors of Diabetic Retinopathy Among Type 2 Diabetes Patients at a Tertiary Care Center Journal of the Endocrine Society, Volume 4, Issue Supplement_1, April-May 2020, MON-667, Published : May 8 2020

Presentations and Abstracts• Aamer A, Mulvaney E, Wright RM. Introducing Teams of Health Sciences Students to Age

Friendly Care. 20th Annual American Geriatric Society Conference, April 2020. Journal of the American Geriatrics Society. Volume 68, Issue S1, 2020 Annual Scientific Meeting Pages: I-X, S1-S385. Cancelled due to Covid-19

• Aamer A, Bernstein I, Sandhu R, Chandra A, Cyr K, Perera S, Naumovski J. Daylight and Nursing Home Falls: Not Just Weekend Syndrome. Journal of the American Geriatrics Society. Volume 68, Issue S1, 2020 Annual Scientific Meeting Pages: I-X, S1-S385 April 2020, 20th Annual American Geriatric Society Conference. Cancelled due to Covid-19

• Aamer A, Chandra A, Naumovski J. To anticoagulate or not: the technology to choose wisely. Journal of the American Geriatrics Society. Volume 68, Issue S1 2020 Annual Scientific Meeting Pages: I-X, S1-S385 April 2020, 20th Annual American Geriatric Society Conference. Cancelled due to Covid-19

Ilia Bernstein, BMBS Presentations and Abstracts

• Bernstein I, Aamer A, Chandra AS, Sandhu R, Hassan S. Biotin: Unforeseen Consequences. Abstract. Journal of the American Geriatrics Society. S90. 2020 Supplement., 20th Annual American Geriatrics Society Conference. Cancelled due to Covid-19

• Bernstein I, Sandhu R, Aamer A, Chandra AS, Yacko M, Bateman J, Naumovski J. Transitions of Care: Strengthening the Weakest Link. Abstract. Journal of the American Geriatrics Society. S203. 2020 Supplement., 20th Annual American Geriatrics Society Conference. Cancelled due to Covid-19

Anita Shalini Chandra, MD Presentations and Abstracts

• Chandra, A. S., and S. Rana. "Malignant Peripheral Nerve Sheath Tumor Presenting as a Rare Cause of Hip Pain in an Older Adult: A Case Report." Journal of the American Geriatrics Society. Vol. 68. 111. Published: April 2020, 20th Annual American Geriatrics Society Conference Cancelled due to Covid-19

TEACHING

44

Department of Medicine 2020 Annual Report

Postdoctoral Fellows* Indicates departing fellow

*Rachel Jantea, MD Mentors: Rollin Wright, MD, MA, MPH, and Debra Weiner, MD Dr. Jantea designed a collaborative-practice curriculum for health profession students and provid-ers caring for older adults on a neurological trauma unit at UPMC. She is studying its impact on educational and healthcare outcomes.

45

Division of Geriatric Medicine

Non-original research publications are in italics. Geriatric Medicine faculty are in bold.

July 1, 2019 to June 30, 2020

ONE-YEARBIBLIOGRAPHY

Adami G, Saag KG, Mudano AS, Rahn EJ, Wright NC, Outman RC, Greenspan SL, LaCroix AZ, Nieves JW, Silverman SL, Siris ES, Watts NB, Miller MJ, La-dores S, Curtis JR, Danila MI. Factors associated with the contemplative stage of readiness to initiate osteopo-rosis treatment. Osteoporos Int. 2020 Jul;31(7):1283-1290. Epub 2020 Feb 4.

Alqahtani BA, Sparto PJ, Whitney SL, Greenspan SL, Perera S, Brach JS. Psy-chometric properties of instrumented postural sway measures recorded in community settings in independent living older adults. BMC Geriatr. 2020 Feb 28;20(1):82.

Alqahtani BA, Sparto PJ, Whitney SL, Greenspan SL, Perera S, VanS-wearingen J, Brach JS. Effect of Com-munity-Based Group Exercise Inter-ventions on Standing Balance and Strength in Independent Living Older Adults. J Geriatr Phys Ther. 2019 Oct/Dec;42(4):E7-E15.

Balachandran A, Gundermann DM, Walkup MP, King AC, Ambrosius WT, Kritchevsky SB, Pahor M, Newman AB, Manini TM. Associa-tion of Fish Oil and Physical Activity on Mobil-ity Disability in Older Adults. Med Sci Sports Exerc. 2020 Apr;52(4):859-867.

Balte PP, Chaves PHM, Couper DJ, Enright P, Jacobs DR Jr, Kalhan R, Kronmal RA, Loehr LR, London SJ, Newman AB, O’Connor GT, Schwartz JE, Smith BM, Smith LJ, White WB, Yende S, Oelsner EC. Association of Nonob-structive Chronic Bronchitis With Respiratory Health Outcomes in Adults. JAMA Intern Med. 2020 May 1;180(5):676-686.

Bhasin S, Travison TG, Manini TM, Patel S, Pencina KM, Fielding RA, Magaziner JM, New-man AB, Kiel DP, Cooper C, Guralnik JM, Cauley JA, Arai H, Clark BC, Landi F, Schaap LA, Perei-ra SL, Rooks D, Woo J, Woodhouse LJ, Binder E, Brown T, Shardell M, Xue QL, DʼAgostino RB Sr, Orwig D, Gorsicki G, Correa-De-Araujo R, Caw-thon PM. Sarcopenia Definition: The Position Statements of the Sarcopenia Definition and

Outcomes Consortium. J Am Geriatr Soc. 2020 Jul;68(7):1410-1418. Epub 2020 Mar 9.

Bowen E, Nayfe R, Milburn N, Mayo H, Reid MC, Fraenkel L, Weiner D, Halm EA, Makris UE. Do Decision Aids Bene-fit Patients with Chronic Musculoskel-etal Pain? A Systematic Review. Pain Med. 2020 May 1;21(5):951-969.

Brach JS, VanSwearingen JM, Gil A, Na-dkarni NK, Kriska A, Cham R, Perera S. Program to improve mobility in aging (PRIMA) study: Methods and rationale of a task-oriented motor learning ex-ercise program. Contemp Clin Trials. 2020 Feb;89:105912. Epub 2019 Dec 12.

Breitbach ME, Greenspan S, Resnick NM, Perera S, Gurkar AU, Absher D, Levine AS. Exonic Variants in Aging-Re-lated Genes Are Predictive of Pheno-typic Aging Status. Front Genet. 2019 Dec 19;10:1277. eCollection 2019.

Cawthon PM, Orwoll ES, Ensrud KE, Cauley JA, Kritchevsky SB, Cummings SR, Newman A. As-sessing the Impact of the COVID-19 Pandemic and Accompanying Mitigation Efforts on Older Adults. J Gerontol A Biol Sci Med Sci. 2020 Sep 16;75(9):e123-e125.

Chowdhury EK, Nelson MR, Ernst ME, Margo-lis KL, Beilin LJ, Johnston CI, Woods RL, Mur-ray AM, Wolfe R, Storey E, Shah RC, Lockery JE, Tonkin AM, Newman AB, Williamson JD, Abhayaratna WP, Stocks NP, Fitzgerald SM, Orchard SG, Trevaks RE, Donnan GA, Grimm R, McNeil JJ, Reid CM; ASPREE Investigator Group. Factors Associated With Treatment and Control of Hypertension in a Healthy El-derly Population Free of Cardiovascular Dis-ease: A Cross-sectional Study. Am J Hypertens. 2020 Apr 1;33(4):350-361.

Conley RB, Adib G, Adler RA, Åkesson KE, Alex-ander IM, Amenta KC, Blank RD, Brox WT, Car-mody EE, Chapman-Novakofski K, Clarke BL, Cody KM, Cooper C, Crandall CJ, Dirschl DR, Eagen TJ, Elderkin AL, Fujita M, Greenspan SL, Halbout P, Hochberg MC, Javaid M, Jeray KJ, Kearns AE, King T, Koinis TF, Koontz JS, Kuzma

M, Lindsey C, Lorentzon M, Lyritis GP, Michaud LB, Miciano A, Morin SN, Mujahid N, Napoli N, Olenginski TP, Puzas JE, Rizou S, Rosen CJ, Saag K, Thompson E, Tosi LL, Tracer H, Khos-la S, Kiel DP. Secondary Fracture Prevention: Consensus Clinical Recommendations from a Multistakeholder Coalition. J Bone Miner Res. 2020 Jan;35(1):36-52/J Orthop Trauma. 2020 Apr;34(4):e125-e141.

Coyle PC, Perera S, Albert SM, Fre-burger JK, VanSwearingen JM, Brach JS. Potential long-term impact of “On The Move” group-exercise program on falls and healthcare utilization in old-er adults: an exploratory analysis of a randomized controlled trial. BMC Geri-atr. 2020 Mar 16;20(1):105.

Coyle PC, Perera S, Shuman V, VanS-wearingen J, Brach JS. Development and validation of person-centered cut-points for the figure-of-8-walk test of mobility in community-dwelling older adults. J Gerontol A Biol Sci Med Sci. 2020 Feb 1:glaa035. Online ahead of print.

Custodero C, Anton SD, Beavers DP, Man-kowski RT, Lee SA, McDermott MM, Fielding RA, Newman AB, Tracy RP, Kritchevsky SB, Ambrosius WT, Pahor M, Manini TM; ENRGISE study investigators. The relationship between interleukin-6 levels and physical performance in mobility-limited older adults with chronic low-grade inflammation: The ENRGISE Pi-lot study. Arch Gerontol Geriatr. 2020 Sep-Oct;90:104131. Epub 2020 May 30.

Damluji AA, Huang J, Bandeen-Roche K, Forman DE, Gerstenblith G, Moscu-cci M, Resar JR, Varadhan R, Walston JD, Segal JB. Frailty Among Older Adults With Acute Myocardial Infarction and Outcomes From Percutaneous Coro-nary Interventions. J Am Heart Assoc. 2019 Sep 3;8(17):e013686. Epub 2019 Aug 31.

Deelen J, Evans DS, Arking DE, Tesi N, Nygaard M, Liu X, Wojczynski MK, Biggs ML, van der Spek A, Atzmon G, Ware EB, Sarnowski C,

BIBLIOGRAPHY

46

Department of Medicine 2020 Annual Report

Smith AV, Seppälä I, Cordell HJ, Dose J, Amin N, Arnold AM, Ayers KL, Barzilai N, Becker EJ, Beekman M, Blanché H, Christensen K, Chris-tiansen L, Collerton JC, Cubaynes S, Cummings SR, Davies K, Debrabant B, Deleuze JF, Duncan R, Faul JD, Franceschi C, Galan P, Gudnason V, Harris TB, Huisman M, Hurme MA, Jagger C, Jansen I, Jylhä M, Kähönen M, Karasik D, Kardia SLR, Kingston A, Kirkwood TBL, Launer LJ, Lehtimäki T, Lieb W, Lyytikäinen LP, Mar-tin-Ruiz C, Min J, Nebel A, Newman AB, Nie C, Nohr EA, Orwoll ES, Perls TT, Province MA, Psa-ty BM, Raitakari OT, Reinders MJT, Robine JM, Rotter JI, Sebastiani P, Smith J, Sørensen TIA, Taylor KD, Uitterlinden AG, van der Flier W, van der Lee SJ, van Duijn CM, van Heemst D, Vaupel JW, Weir D, Ye K, Zeng Y, Zheng W, Hol-stege H, Kiel DP, Lunetta KL, Slagboom PE, Mu-rabito JM. A meta-analysis of genome-wide as-sociation studies identifies multiple longevity genes. Nat Commun. 2019 Aug 14;10(1):3669.

Dichter ME, Makaroun L, Tuepker A, True G, Montgomery AE, Iverson K. Middle-aged Women’s Experiences of Intimate Partner Violence Screening and Disclosure: “It’s a private matter. It’s an embarrassing situation”. J Gen Intern Med. 2020 Jun 8. Online ahead of print.

Dodda BR, Bondi CD, Hasan M, Claf-shenkel WP, Gallagher KM, Kotlarczyk MP, Sethi S, Buszko E, Latimer JJ, Cline JM, Witt-Enderby PA, Davis VL. Co-administering Melatonin With an Estradiol-Progesterone Menopausal Hormone Therapy Represses Mam-mary Cancer Development in a Mouse Model of HER2-Positive Breast Cancer. Front Oncol. 2019 Jul 9;9:525. eCollec-tion 2019.

Drew DA, Katz R, Kritchevsky S, Ix JH, Shlipak MG, Newman AB, Hoofnagle AN, Fried LF, Sarnak M, Gutiérrez OM. Fibroblast Growth Factor 23 and Blood Pressure in Older Adults: The Health, Aging, and Body Composition Study. Hypertension. 2020 Jul;76(1):236-243. Epub 2020 May 18.

Drwal KR, Forman DE, Wakefield BJ, El Accaoui RN. Cardiac Rehabilitation During COVID-19 Pandemic: Highlighting the Value of Home-Based Programs. Telemed J E Health. 2020 Jun 17. Online ahead of print.

Dumyati G, Nace DA, Jump RLP. Do Clean Common Areas Save Lives?. J Am Geriatr Soc. 2020 Mar;68(3):460-462. Epub 2019 Dec 18.

Elstgeest LEM, Schaap LA, Heymans MW, Hengeveld LM, Naumann E, Houston DK, Kritchevsky SB, Simonsick EM, Newman AB, Farsijani S, Visser M, Wijnhoven HAH; Health ABC Study. Sex-and race-specific associa-tions of protein intake with change in muscle mass and physical function in older adults: the Health, Aging, and Body Composition (Health ABC) Study. Am J Clin Nutr. 2020 Jul 1;112(1):84-95.

Flint KM, Stevens-Lapsley J, Forman DE. Car-diac Rehabilitation in Frail Older Adults With Cardiovascular Disease: A NEW DIAGNOSTIC AND TREATMENT PARADIGM. J Cardiopulm Re-habil Prev. 2020 Mar;40(2):72-78.

Forman DE, Peterson LR. Cardiac Reha-bilitation: You Can’t Have “Too Much of a Good Thing”. J Card Fail. 2020 Jun 27:S1071-9164(20)30744-2. Online ahead of print.

Forman DE, Stone NJ, Grundy SM. Treating Hypercholesterolemia in Older Adults. JAMA. 2019 Aug 20;322(7):695.

Forman DE. Cardiac Rehabilitation for Old-er Adults: Vital Opportunity to Improve Pa-tient-Centered Cardiovascular Disease Care amid Worldwide Patient Aging. Clin Geriatr Med. 2019 Nov;35(4):xiii-xiv. Epub 2019 Aug 21.

Frentzel E, Jump RLP, Archbald-Pannone L, Nace DA, Schweon SJ, Gaur S, Naqvi F, Pandya N, Mercer W; Infection Advisory Subcommittee of AMDA, The Society for Post-Acute and Long-Term Care Medicine. Recommendations for Mandatory Influenza Vaccinations for Health Care Personnel From AMDA’s Infection Adviso-ry Subcommittee. J Am Med Dir Assoc. 2020 Jan;21(1):25-28.e2.

Garg PK, Tan AX, Odden MC, Gardin JM, Lo-pez OL, Newman AB, Rawlings AM, Muka-mal KJ. Brachial Flow-mediated Dilation and Risk of Dementia: The Cardiovascular Health Study. Alzheimer Dis Assoc Disord. 2020 Jul-Sep;34(3):272-274.

Gaur S, Dumyati G, Nace DA, Jump RLP. Unprecedented solutions for extraordinary times: Helping long-term care settings deal with the COVID-19 pandemic. Infect Control Hosp Epidemiol. 2020 Jun;41(6):729-730.

Gaur S, Pandya N, Dumyati G, Nace DA, Pan-dya K, Jump RLP. A Structured Tool for Com-munication and Care Planning in the Era of the COVID-19 Pandemic. J Am Med Dir Assoc. 2020 Jul;21(7):943-947.

Glynn NW, Gmelin T, Santanasto AJ, Lovato LC, Lange-Maia BS, Nicklas BJ, Fielding RA, Manini TM, Myers VH, de Rekeneire N, Spring BJ, Pahor M, King AC, Rejeski WJ, Newman AB; Lifestyle Interventions and Independence for Elders Study Group. Impact of Baseline Fatigue on a Physical Activity Intervention to Prevent Mobility Disability. J Am Geriatr Soc. 2020 Mar;68(3):619-624. Epub 2019 Dec 22.

Goyal P, Gorodeski EZ, Marcum ZA, Forman DE. Cardiac Rehabilitation to Optimize Medi-cation Regimens in Heart Failure. Clin Geriatr Med. 2019 Nov;35(4):549-560. Epub 2019 Jun 21.

Goyal P, Kneifati-Hayek J, Archambault A, Mehta K, Levitan EB, Chen L, Diaz I, Hollenberg J, Hanlon JT, Lachs MS, Maurer MS, Safford MM. Prescribing Patterns of Heart-Failure-Exacerbating Medications Following a Heart Failure Hospitalization. JACC Heart Fail. 2020

Jan;8(1):25-34. Epub 2019 Nov 6.

Häberle AD, Biggs ML, Cushman M, Psaty BM, Newman AB, Shlipak MG, Gottdiener J, Wu C, Gardin JM, Bansal N, Odden MC. Level and change in N-terminal pro B-type Natriuretic Peptide and kidney function and survival to age 90. J Gerontol A Biol Sci Med Sci. 2020 May 17:glaa124. Online ahead of print.

Hamsanathan S, Alder JK, Sellares J, Rojas M, Gurkar AU, Mora AL. Cellular Senescence: The Trojan Horse in Chronic Lung Diseases. Am J Respir Cell Mol Biol. 2019 Jul;61(1):21-30.

Hanlon JT, Schmader KE. Measuring Underuse and Overuse of Medications. J Am Geriatr Soc. 2019 Nov;67(11):2428. Epub 2019 Aug 7.

Hawley CE, Roefaro J, Forman DE, Orkaby AR. Statins for Primary Prevention in Those Aged 70 Years and Older: A Critical Review of Recent Cholesterol Guidelines. Drugs Aging. 2019 Aug;36(8):687-699.

Hengeveld LM, Wijnhoven HAH, Olthof MR, Brouwer IA, Simonsick EM, Kritchevsky SB, Houston DK, Newman AB, Visser M. Prospec-tive Associations of Diet Quality With Incident Frailty in Older Adults: The Health, Aging, and Body Composition Study. J Am Geriatr Soc. 2019 Sep;67(9):1835-1842. Epub 2019 Jul 2.

Inzitari M, Metti A, Rosano C, Udina C, Pérez LM, Carrizo G, Verghese J, Newman AB, Stu-denski S, Rosso AL. Qualitative neurological gait abnormalities, cardiovascular risk fac-tors and functional status in older commu-nity-dwellers without neurological diseases: The Healthy Brain Project. Exp Gerontol. 2019 Sep;124:110652. Epub 2019 Jul 6.

Kapoor A, Field T, Handler S, Fisher K, Saphirak C, Crawford S, Fouayzi H, Johnson F, Spenard A, Zhang N, Gur-witz JH. Adverse Events in Long-term Care Residents Transitioning From Hospital Back to Nursing Home. JAMA Intern Med. 2019 Jul 22;179(9):1254-61. Online ahead of print.

Karp JF, Zhang J, Wahed AS, Ander-son S, Dew MA, Fitzgerald GK, Weiner DK, Albert S, Gildengers A, Butters M, Reynolds CF 3rd. Improving Patient Reported Outcomes and Prevent-ing Depression and Anxiety in Old-er Adults With Knee Osteoarthritis: Results of a Sequenced Multiple As-signment Randomized Trial (SMART) Study. Am J Geriatr Psychiatry. 2019 Oct;27(10):1035-1045. Epub 2019 Mar 21.

Kellar G, Allsup K, Delligatti A, Althouse AD, Forman DE. Enhancing Function-al Risk Stratification in Contemporary Cardiac Rehabilitation: responding to patients who are increasingly older and more physically impaired. J Car-diopulm Rehabil Prev. 2020 Jun 19.

47

Division of Geriatric Medicine

Online ahead of print.

Kotlarczyk MP, Perera S, Resnick NM, Nace DA, Greenspan SL. Ear-ly changes in bone turnover predict longer-term changes in bone mineral density but not trabecular bone score in frail older women. Arch Osteoporos. 2020 May 26;15(1):79.

Kuipers AL, Wojczynski MK, Barinas-Mitchell E, Minster RL, Wang L, Feitosa MF, Kulminski A, Thyagarajan B, Lee JH, Province MA, Newman AB, Zmuda JM; Long-Life Family Study. Ge-nome-wide linkage analysis of carotid artery traits in exceptionally long-lived families. Ath-erosclerosis. 2019 Dec;291:19-26. Epub 2019 Oct 10.

Laxton CE, Nace DA, Nazir A; AMDA–The So-ciety for Post-Acute and Long-Term Care Med-icine. Solving the COVID-19 Crisis in Post-Acute and Long-Term Care. J Am Med Dir Assoc. 2020 Jul;21(7):885-887. Epub 2020 Jun 16.

Le Couteur DG, Anderson RM, Newman AB. COVID-19 Through the Lens of Gerontol-ogy. J Gerontol A Biol Sci Med Sci. 2020 Sep 16;75(9):e119-e120.

Leclerc AA, Gillespie AI, Tadic SD, Smith LJ, Rosen CA. The prevalence of cognitive impairment in laryngology treatment-seeking patients. Laryngo-scope. 2020 Aug;130(8):2003-2007. Epub 2019 Oct 25.

Liao CY, Nace DA, Crnich CJ, Bah-rainian M, Ford JH. Effect of antibiotic time-outs on modification of antibi-otic prescriptions in nursing homes. Infect Control Hosp Epidemiol. 2020 Jun;41(6):635-640.

Lingler JH, Sereika SM, Butters MA, Co-hen AD, Klunk WE, Knox ML, McDade E, Nadkarni NK, Roberts JS, Tamres LK, Lopez OL. A randomized controlled trial of amyloid positron emission to-mography results disclosure in mild cognitive impairment. Alzheimers De-ment. 2020 Jun 26. Online ahead of print.

Madill ES, Samuels R, Newman DP, Boudreaux-Kelley M, Weiner DK. De-velopment of an Evaluative, Educa-tional, and Communication-Facilitating App for Older Adults with Chronic Low Back Pain: Patient Perceptions of Us-ability and Utility. Pain Med. 2019 Nov 1;20(11):2120-2128.

Makaroun LK, Bachrach RL, Rosland AM. El-der Abuse in the Time of COVID-19-Increased Risks for Older Adults and Their Caregivers. Am J Geriatr Psychiatry. 2020 Aug;28(8):876-880. Epub 2020 May 19.

Makaroun LK, Brignone E, Rosland

AM, Dichter ME. Association of Health Conditions and Health Service Uti-lization With Intimate Partner Vio-lence Identified via Routine Screen-ing Among Middle-Aged and Older Women. JAMA Netw Open. 2020 Apr 1;3(4):e203138.

Marron MM, Harris TB, Boudreau RM, Clish CB, Moore SC, Murphy RA, Murthy VL, Sanders JL, Shah RV, Tseng GC, Wendell SG, Zmuda JM, Newman AB. A metabolite composite score attenuated a substantial portion of the higher mortality risk associated with frailty among community-dwelling older adults. J Gerontol A Biol Sci Med Sci. 2020 May 3:glaa112. Online ahead of print.

Marron MM, Wendell SG, Boudreau RM, Clish CB, Santanasto AJ, Tseng GC, Zmuda JM, New-man AB. Metabolites associated with walking ability among the oldest old from the CHS All Stars study. J Gerontol A Biol Sci Med Sci. 2020 Jan 23:glaa030. Online ahead of print.

Marron MM, Wojczynski MK, Minster RL, Bou-dreau RM, Sebastiani P, Cosentino S, Thyaga-rajan B, Ukraintseva SV, Schupf N, Christensen K, Feitosa M, Perls T, Zmuda JM, Newman AB; Long Life Family Study. Heterogeneity of healthy aging: comparing long-lived families across five healthy aging phenotypes of blood pressure, memory, pulmonary function, grip strength, and metabolism. Geroscience. 2019 Aug;41(4):383-393. Epub 2019 Jul 22.

Mattos MK, Sereika SM, Beach SR, Kim H, Klunk WE, Knox M, Nadkarni NK, Parker LS, Roberts JS, Schulz R, Tamres L, Lingler JH. Re-search Use of Ecological Momentary Assess-ment for Adverse Event Monitoring Following Amyloid-β Results Disclosure. J Alzheimers Dis. 2019;71(4):1071-1079.

McDermott MM, Newman AB. Preserving Clinical Trial Integrity During the Coronavirus Pandemic. JAMA. 2020 Jun 2;323(21):2135-2136.

Merrill Z, Perera S, Cham R. Predictive regression modeling of body segment parameters using individual-based anthropometric measurements. J Bio-mech. 2019 Nov 11;96:109349. Epub 2019 Oct 8.

Nace DA, Fridkin SK. Are Antibiograms Ready for Prime Time in the Nursing Home?. J Am Med Dir Assoc. 2020 Jan;21(1):8-11.

Nace DA, Hanlon JT, Crnich CJ, Drinka PJ, Schweon SJ, Anderson G, Perera S. A Multifaceted Antimicrobial Steward-ship Program for the Treatment of Un-complicated Cystitis in Nursing Home Residents. JAMA Intern Med. 2020 May 11;180(7):1-9. Online ahead of print.

Nadkarni NK, Tudorascu D, Camp-bell E, Snitz BE, Cohen AD, Halligan E, Mathis CA, Aizenstein HJ, Klunk WE. Association Between Amyloid-β,

Small-vessel Disease, and Neurode-generation Biomarker Positivity, and Progression to Mild Cognitive Impair-ment in Cognitively Normal Individu-als. J Gerontol A Biol Sci Med Sci. 2019 Oct 4;74(11):1753-1760.

Nayak S, Greenspan SL. Bisphospho-nate drug holidays. Osteoporos Int. 2019 Dec;30(12):2525. Epub 2019 Oct 15.

Nayak S, Greenspan SL. Cost-effec-tiveness of five versus ten years of alendronate treatment prior to drug holiday for women with osteoporosis. Osteoporos Int. 2020 Jul;31(7):1273-1282. Epub 2020 Feb 4.

Newman AB, Kritchevsky SB, Guralnik JM, Cummings SR, Salive M, Kuchel GA, Schrack J, Morris MC, Weir D, Baccarelli A, Murabito JM, Ben-Shlomo Y, Espeland MA, Kirkland J, Melzer D, Ferrucci L. Accelerating the Search for Inter-ventions Aimed at Expanding the Health Span in Humans: The Role of Epidemiology. J Geron-tol A Biol Sci Med Sci. 2020 Jan 1;75(1):77-86.

Newman AB. James Edgar Paullin: Pioneer in Geriatrics and Gerontology. J Gerontol A Biol Sci Med Sci. 2020 Jan 1;75(1):115-116.

Niznik JD, Hunnicutt JN, Zhao X, Mor MK, Sileanu F, Aspinall SL, Springer SP, Ersek MJ, Gellad WF, Schleiden LJ, Han-lon JT, Thorpe JM, Thorpe CT. Dein-tensification of Diabetes Medications among Veterans at the End of Life in VA Nursing Homes. J Am Geriatr Soc. 2020 Apr;68(4):736-745. Epub 2020 Feb 17.

Niznik JD, Zhao X, He M, Aspinall SL, Hanlon JT, Nace D, Thorpe JM, Thor-pe CT. Factors Associated With Depre-scribing Acetylcholinesterase Inhibi-tors in Older Nursing Home Residents With Severe Dementia. J Am Geriatr Soc. 2019 Sep;67(9):1871-1879. Epub 2019 Jun 4.

Niznik JD, Zhao X, He M, Aspinall SL, Hanlon JT, Hanson LC, Nace D, Thor-pe JM, Thorpe CT. Risk for Health Events After Deprescribing Acetylcho-linesterase Inhibitors in Nursing Home Residents With Severe Dementia. J Am Geriatr Soc. 2020 Apr;68(4):699-707. Epub 2019 Nov 26.

Niznik JD, Zhao X, He M, Aspinall SL, Hanlon JT, Nace D, Thorpe JM, Thorpe CT. Impact of deprescribing AChEIs on aggressive behaviors and antipsychot-ic prescribing. Alzheimers Dement. 2020 Apr;16(4):630-640. Epub 2020 Feb 13.

O’Neill D, Forman DE. Never Too Old for Car-diac Rehabilitation. Clin Geriatr Med. 2019

BIBLIOGRAPHY

48

Department of Medicine 2020 Annual Report

Nov;35(4):407-421. Epub 2019 Jul 2.

O’Neill D, Forman DE. The importance of physical function as a clinical outcome: As-sessment and enhancement. Clin Cardiol. 2020 Feb;43(2):108-117. Epub 2019 Dec 11.

O’Neill D, Stone NJ, Forman DE. Primary Pre-vention Statins in Older Adults: Personalized Care for a Heterogeneous Population. J Am Geriatr Soc. 2020 Mar;68(3):467-473. Epub 2020 Jan 22.

Odden MC, Rawlings AM, Arnold AM, Cushman M, Biggs ML, Psaty BM, Newman AB. Patterns of Cardiovascular Risk Factors in Old Age and Survival and Health Status at 90. J Gerontol A Biol Sci Med Sci. 2020 Apr 8:glaa043. Online ahead of print.

Odden MC, Rawlings AM, Khodadadi A, Fern X, Shlipak MG, Bibbins-Domingo K, Covinsky K, Kanaya AM, Lee A, Haan MN, Newman AB, Psaty BM, Peralta CA. Heterogeneous Exposure Associations in Observational Co-hort Studies: The Example of Blood Pressure in Older Adults. Am J Epidemiol. 2020 Jan 31;189(1):55-67.

Oelsner EC, Balte PP, Bhatt SP, Cassano PA, Couper D, Folsom AR, Freedman ND, Jacobs DR Jr, Kalhan R, Mathew AR, Kronmal RA, Loehr LR, London SJ, Newman AB, O’Connor GT, Schwartz JE, Smith LJ, White WB, Yende S. Lung function decline in former smokers and low-intensity current smokers: a secondary data analysis of the NHLBI Pooled Cohorts Study. Lancet Respir Med. 2020 Jan;8(1):34-44. Epub 2019 Oct 9.

Pahor M, Guralnik JM, Anton SD, Ambrosius WT, Blair SN, Church TS, Espeland MA, Field-ing RA, Gill TM, Glynn NW, Groessl EJ, King AC, Kritchevsky SB, Manini TM, McDermott MM, Miller ME, Newman AB, Williamson JD. Impact and Lessons From the Lifestyle Inter-ventions and Independence for Elders (LIFE) Clinical Trials of Physical Activity to Prevent Mobility Disability. J Am Geriatr Soc. 2020 Apr;68(4):872-881. Epub 2020 Feb 27.

Perera S, VanSwearingen J, Shuman V, Brach JS. Assessing gait efficacy in older adults: An analysis using item response theory. Gait Posture. 2020 Mar;77:118-124. Epub 2020 Jan 28.

Pickering AN, Hamm ME, Dawdani A, Hanlon JT, Thorpe CT, Gellad WF, Ra-domski TR. Older Patient and Caregiver Perspectives on Medication Value and Deprescribing: A Qualitative Study. J Am Geriatr Soc. 2020 Apr;68(4):746-753. Epub 2020 Feb 17.

Pruskowski J, Childers J, Moore PA, Ze-maitis MA, Bauer RE, Deverts DJ, Elnic-ki DM, Levine SC, Kaufman R, Dziabiak MP, Spallek H, Weiner DK, Horvath Z. Managing Acute Pain and Opioid Risks Following Wisdom Teeth Extraction: An Illustrative Case. MedEdPORTAL.

2019 Nov 22;15:10855.

Pruskowski J, Sakely H, Handler S. De-velopment of a required longitudinal residency experience focused on de-prescribing. Am J Health Syst Pharm. 2019 Feb 1;76(4):236-241.

Pruskowski JA, Springer S, Thorpe CT, Klein-Fedyshin M, Handler SM. Does Deprescribing Improve Quality of Life? A Systematic Review of the Literature. Drugs Aging. 2019 Dec;36(12):1097-1110.

Radomski TR, Zhao X, Hanlon JT, Thor-pe JM, Thorpe CT, Naples JG, Sileanu FE, Cashy JP, Hale JA, Mor MK, Haus-mann LRM, Donohue JM, Suda KJ, Stroupe KT, Good CB, Fine MJ, Gellad WF. Use of a medication-based risk adjustment index to predict mortal-ity among veterans dually-enrolled in VA and medicare. Healthc (Amst). 2019 Dec;7(4):S2213-0764(18)30230-6. Epub 2019 Apr 26.

Rajakumar K, Moore CG, Khalid AT, Vallejo AN, Virji MA, Holick MF, Green-span SL, Arslanian S, Reis SE. Effect of vitamin D3 supplementation on vas-cular and metabolic health of vitamin D-deficient overweight and obese chil-dren: a randomized clinical trial. Am J Clin Nutr. 2020 Apr 1;111(4):757-768.

Regan JA, Kitzman DW, Leifer ES, Kraus WE, Fleg JL, Forman DE, Whellan DJ, Wojdyla D, Parikh K, O’Connor CM, Mentz RJ. Impact of Age on Comorbid-ities and Outcomes in Heart Failure With Reduced Ejection Fraction. JACC Heart Fail. 2019 Dec;7(12):1056-1065.

Rich MW, Goyal P, Forman DE. Age and Heart Failure Trials - Lessons from DAPA-HF. J Card Fail. 2020 Mar;26(3):191-192.

Ryan J, Storey E, Murray AM, Woods RL, Wolfe R, Reid CM, Nelson MR, Chong TTJ, Williamson JD, Ward SA, Lockery JE, Orchard SG, Trevaks R, Kirpach B, Newman AB, Ernst ME, McNeil JJ, Shah RC; ASPREE Investigator Group. Ran-domized placebo-controlled trial of the effects of aspirin on dementia and cognitive decline. Neurology. 2020 Jul 21;95(3):e320-e331. Epub 2020 Mar 25.

Schaaf S, Huang W, Perera S, Conley Y, Belfer I, Jayabalan P, Tremont K, Coel-ho P, Ernst S, Cortazzo M, Weiner D, Vo N, Kang J, Sowa G. Association of Protein and Genetic Biomarkers with Response to Lumbar Epidural Steroid Injections in Subjects with Axial Low Back Pain. Am J Phys Med Rehabil. 2020 Jun 22. Online ahead of print.

Scheunemann LP, White JS, Prinjha

S, Hamm ME, Girard TD, Skidmore ER, Reynolds CF 3rd, Leland NE. Post-In-tensive Care Unit Care. A Qualitative Analysis of Patient Priorities and Impli-cations for Redesign. Ann Am Thorac Soc. 2020 Feb;17(2):221-228.

Shardell M, Drew DA, Semba RD, Harris TB, Cawthon PM, Simonsick EM, Kalyani RR, Schwartz AV, Kritchevsky SB, Newman AB. Plasma Soluble αKlotho, Serum Fibroblast Growth Factor 23, and Mobility Disability in Community-Dwelling Older Adults. J Endo-cr Soc. 2020 Apr 30;4(5):bvz032. eCollection 2020 May 1.

Shuman V, Coyle PC, Perera S, VanS-wearingen JM, Albert SM, Brach JS. As-sociation between improved mobility and distal health outcomes. J Gerontol A Biol Sci Med Sci. 2020 Apr 9:glaa086. Online ahead of print.

Skaar E, Øksnes A, Eide LSP, Norekvål TM, Ranhoff AH, Nordrehaug JE, Forman DE, Schoenenberger AW, Hufthammer KO, Kuiper KK, Bleie Ø, Packer EJS, Langørgen J, Haaverstad R, Schaufel MA. Baseline frailty status and outcomes important for shared decision-making in older adults receiv-ing transcatheter aortic valve implan-tation, a prospective observational study. Aging Clin Exp Res. 2020 Mar 19. Online ahead of print.

Sloane PD, Zimmerman S, Nace DA. Progress and Challenges in the Management of Nurs-ing Home Infections. J Am Med Dir Assoc. 2020 Jan;21(1):1-4.

Snitz BE, Tudorascu DL, Yu Z, Camp-bell E, Lopresti BJ, Laymon CM, Minhas DS, Nadkarni NK, Aizenstein HJ, Klunk WE, Weintraub S, Gershon RC, Cohen AD. Associations between NIH Toolbox Cognition Battery and in vivo brain amyloid and tau pathol-ogy in non-demented older adults. Alzheimers Dement (Amst). 2020 May 15;12(1):e12018. eCollection 2020.

Speiser JL, Callahan KE, Houston DK, Fanning J, Gill TM, Guralnik JM, Newman AB, Pahor M, Rejeski WJ, Miller ME. Machine Learning in Aging: An Example of Developing Predic-tion Models for Serious Fall Injury in Older Adults. J Gerontol A Biol Sci Med Sci. 2020 Jun 4:glaa138. Online ahead of print.

Springer SP, Mor MK, Sileanu F, Zhao X, Aspinall SL, Ersek M, Niznik JD, Hanlon JT, Hunnicutt J, Gellad WF, Schleiden LJ, Thorpe JM, Thorpe CT. Incidence and Predictors of Aspirin Discontinuation in Older Adult Veteran Nursing Home Residents at End of Life. J Am Geriatr Soc. 2020 Apr;68(4):725-735. Epub 2020 Feb 13.

49

Division of Geriatric Medicine

Stahl ST, Jung C, Weiner DK, Peciña M, Karp JF. Opioid Exposure Negative-ly Affects Antidepressant Response to Venlafaxine in Older Adults with Chronic Low Back Pain and Depres-sion. Pain Med. 2019 Oct 21:pnz279. Online ahead of print.

Tighe CA, Youk A, Ibrahim SA, Weiner DK, Vina ER, Kwoh CK, Gallagher RM, Bramoweth AD, Hausmann LRM. Pain Catastrophizing and Arthritis Self-Effi-cacy as Mediators of Sleep Disturbance and Osteoarthritis Symptom Severity. Pain Med. 2020 Mar 1;21(3):501-510.

Tyagi S, Perera S, Clarkson BD, Tadic SD, Resnick NM. Nocturnal Excretion in Healthy Older Women and Ratio-nale for a Safer Approach to Sleep Disruption. J Am Geriatr Soc. 2019 Dec;67(12):2610-2614. Epub 2019 Aug 22.

Weiner DK, Gentili A, Fang MA, Garay E, An-naswamy T, Castle S, Joseph L, Lawson L, Lee CC, Makris UE, Rossi MI, Thorn B, Clemens K, Newman D, Perera S. Caring for older veterans with chronic low back pain using a geriatric syndrome approach: Rationale and methods for the aging back clinics (ABC) trial. Contemp Clin Trials. 2020 Jun 25;95:106077. Online ahead of print.

Weiner DK, Gentili A, Rossi M, Cof-fey-Vega K, Rodriguez KL, Hruska KL, Hausmann L, Perera S. Aging Back Clinics-a Geriatric Syndrome Approach to Treating Chronic Low Back Pain in Older Adults: Results of a Preliminary Randomized Controlled Trial. Pain Med. 2020 Feb 1;21(2):274-290.

Westbury LD, Syddall HE, Fuggle NR, Dennison EM, Cauley JA, Shiroma EJ, Fielding RA, New-man AB, Cooper C. Long-term rates of change in musculoskeletal aging and body composi-tion: findings from the Health, Aging and Body Composition Study. Calcif Tissue Int. 2020 Jun;106(6):616-624. Epub 2020 Mar 3.

Wu C, Li YX, Marron MM, Odden MC, New-man AB, Sanders JL. Quantifying and Classi-fying Physical Resilience Among Older Adults: The Health, Aging, and Body Composition Study. J Gerontol A Biol Sci Med Sci. 2020 Sep 25;75(10):1960-1966.

Yende S, Kellum JA, Talisa VB, Peck Palmer OM, Chang CH, Filbin MR, Shapiro NI, Hou PC, Venkat A, LoVecchio F, Hawkins K, Crouser ED, Newman AB, Angus DC. Long-term Host Immune Response Trajectories Among Hospi-talized Patients With Sepsis. JAMA Netw Open. 2019 Aug 2;2(8):e198686.

Yousefzadeh MJ, Zhao J, Bukata C, Wade EA, McGowan SJ, Angelini LA, Bank MP, Gurkar AU, McGuck-ian CA, Calubag MF, Kato JI, Burd CE,

Robbins PD, Niedernhofer LJ. Tissue specificity of senescent cell accumu-lation during physiologic and acceler-ated aging of mice. Aging Cell. 2020 Mar;19(3):e13094. Epub 2020 Jan 25.

Yum B, Archambault A, Levitan EB, Dha-ramdasani T, Kneifati-Hayek J, Han-lon JT, Diaz I, Maurer MS, Lachs MS, Safford MM, Goyal P. Indications for β-Blocker Prescriptions in Heart Fail-ure with Preserved Ejection Fraction. J Am Geriatr Soc. 2019 Jul;67(7):1461-1466. Epub 2019 May 16.

Zhang Y, Vittinghoff E, Pletcher MJ, Allen NB, Zeki Al Hazzouri A, Yaffe K, Balte PP, Alonso A, Newman AB, Ives DG, Rana JS, Lloyd-Jones D, Vasan RS, Bibbins-Domingo K, Gooding HC, de Ferranti SD, Oelsner EC, Moran AE. Associa-tions of Blood Pressure and Cholesterol Levels During Young  Adulthood With Later  Cardio-vascular Events. J Am Coll Cardiol. 2019 Jul 23;74(3):330-341.

Zhang Z, Perera S, Donohue C, Kuro-su A, Mahoney AS, Coyle JL, Sejdic E. The Prediction of Risk of Penetra-tion-Aspiration Via Hyoid Bone Dis-placement Features. Dysphagia. 2020 Feb;35(1):66-72. Epub 2019 Mar 27.

Zhao J, Zhang L, Lu A, Han Y, Colange-lo D, Bukata C, Scibetta A, Yousefza-deh MJ, Li X, Gurkar AU, McGowan SJ, Angelini L, O’Kelly R, Li H, Corbo L, Sano T, Nick H, Pola E, Pilla SPS, Ladi-ges WC, Vo N, Huard J, Niedernhofer LJ, Robbins PD. ATM is a key driver of NF-κB-dependent DNA-damage-in-duced senescence, stem cell dysfunc-tion and aging. Aging (Albany NY). 2020 Mar 22;12(6):4688-4710. Epub 2020 Mar 22.

50

Department of Medicine 2020 Annual Report

CREDITS

50

Department of Medicine 2020 Annual Report

ACKNOWLEDGMENTSAND PHOTO CREDITS

EXECUTIVE EDITORSChristopher O'Donnell, PhDAssistant Vice Chancellor for Special Projects in the Health SciencesExecutive Vice Chair for Academic Affairs, Department of MedicineProfessor of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine

Nichole Radulovich, MEd, CRAExecutive Administrator

SENIOR EDITOR AND GRAPHIC DESIGNKatie Nauman

PROJECT COORDINATOR Kristen Bagwell

DATABASE DEVELOPMENT Nemanja Tomic

GRANTS AND RESEARCH EXPENDITURESJim Jarvis and Ed Hughes

GERIATRIC MEDICINE CONTENT MANAGERSMichelle Ardolino and Vanessa Benkovich

Photo credits:

All photos courtesy of Department of Medicine/University of Pittsburgh faculty and staff except page 3: Flati-con.com; page 9: monkeybusinessimages, iStock photo ID: 141948851; and page 17: Totojang, iStock photo ID: 909908830.

Google maps, accessed October 2020 (pages 14-15).

© 2020 Office of Academic Affairs, Department of Medicine, University of Pittsburgh

1218 Scaife Hall3550 Terrace StreetPittsburgh, PA 15261

Phone 412.648.9636Website www.dom.pitt.edu