Medical Students 2010 - Slide 5 - J.B. Vermorken - Introduction to Clincial Trials
MEDICAL TRIALS
1
161 drug. I have found the most efficacious to be, an infusion of from half a drachm to a drachm of the powder, and repeated, if necessary, in twenty minutes, with the addition of one tea- spoonful of brandy-and-sugar. In this way I have seldom seen even the approach to sickness; but have ALWAYS been re- warded by a safe and speedy termination of my patient’s sufferings. Surely, then,,Dr. Hewitt will agree with me, to carry this question further than he has done. The cause is a righteous one, and deserving our deepest interest. He will, I am sure, pardon my zeal on these interesting points, and the divergence of opinion which exists. It is by these means only that we can arrive at just conclusions; and with so much at stake-the suffering female in our hands-I feel persuaded that only one motive can actuate all. I am. Sir. vours faithfullv. WM. SETH GILL, L.R.C.P. Pentonville, Feb. 1863. MEDICAL TRIALS. GUILDHALL, FRIDAY, JAN. 30TH. Sittings at Nisi Prius. (Before Mr. Justice BYLES and a Common Jury.) TURNER AND ANOTHER V. REYNELL. Mr. Mills, Q.C., and Mr. Marshall Griffith were for the plaintiffs ; and Mr. Lopez was for the defendant. The plaintiffs are surgeons carrying on business in Phillimore- place, and the defendant is an attorney carrying on business in Staple-inn. This action was brought to recover the amount of the plaintiffs’ bill for medical attendance on the defendant’s family, and especially on his wife, who was afflicted with a nervous malady. The plaintiffs having sent in their account, the defendant wrote to say that he could not afford to pay so large a demand, and contrasted their bill with that of previous medical men who had attended his family. Some correspond- ence ensued, but no settlement was effected, and no money paid into court. The plaintiff Turner, having proved his case, was cross ex- amined as to the date of his registry, and that of his partner, and it was objected that Mr. Smith, one of the plaintiffs, was not registered at the time of the performance of the services sued for, although he had been registered since. On this point the learned judge said he was against the defendant. The next objection was that Mr. Turner and Mr. Smith did not enter into partnership until the 29th of September, and it was ruled that the plaintiffs could only recover jointly on that portion of the bill which had been contracted since that date ; for the previous portion of the bill another action must be brought. It was next urged that the plaintiffs, being surgeons, could only recover for surgical operations, such as galvanizing Mrs. Rey. nell, and syringing the defendant’s ears, not having a certifi- cate from the Apothecaries’ Hall. Mr. Justice BYLES remarked: Then, supposing a surgeon and an apothecary to be in partnership, they cannot recover for surgical items in their bill, because one of them is an apothe- cary ; neither can they recover for medicine and attendance, because one of them is a surgeon. In the end a verdict was entered for the plaintiffs for £46 13s. 6d., with leave to move on points of law raised, the Court to have power to make all the requisite amendments, and to grant all needful certificates to entitle the plaintiffs tc their costs. PARISIAN MEDICAL INTELLIGENCE (FROM OUR SPECIAL CORRESPONDENT.) I MENTIONED some months ago, when speaking of the various contributions made to pathology by Dr. Duchenne of Boulogne, that he in 1860 drew attention to a particular form of progressive muscular paralysis-that of the tongue, soft palate, and lip-which had previously escaped attention, or had not, at all events, been recognised as a distinct morbid species. M. Trousseau, in a recent clinical lecture at the Hôtel Dieu, has endorsed all Dr. Duchenne’s views, corrobo- rated the exactitude of his observations, and accepted the new malady defined by this zea’lous investigator as a bona,fide addi- tion to the nosological catalogue. " I saw examples of this disease," said M. Trousseau, " so early as the year 1841, with- out, however, I must confess, recognising its peculiar charac. teristics. I consequently feel that I have no share in a discovery which entirely belongs to Dr. Duchenne, and to this gentleman attaches the credit of having in 1860 called the attention of pathologists to this particular kind of paralysis. On the 4th of June last an example of this form of disease fell under my notice in the case of a printer, aged sixty-two, who was ad- mitted into the Hotel Dieu. This man, of a good constitution and regular habits, in the month of March, 1862, perceived for the first time some difficulty in pronouncing and articulating words. A month later a new symptom was added to the first. He found that during his meals the food was apt to collect between the teeth and the cheeks, and rendered the use of the finger necessary in order to bring the food back between the teeth, the tongue no longer performing this office. Moreover, the saliva was apt to collect in the mouth, and required to be frequently ejected. In this state the patient first came under my notice. There existed a paralysis of the orbicularis oris, and an almost complete absence of the power of speech, not from any laryngeal defect, but from paralysis of the lips and tongue. None of the muscles of the face, except the orbicu- laris, were affected. The tone of the voice was nasal, due no doubt to defective muscular power in the soft palate. The swallowing of solid and liquid food could be effected at will, as also the deglutition of the saliva ; but the intervention of the act of volition was necessary on each occasion. The instinctive deglutition by which the mouth when full of saliva is in the normal state emptied, had ceased to occur." This symptom, according to M. Duchenne, belongs to an early period of the malady. After having passed the summer in the wards of M. Empis, the patient fell under M. Trousseau’s immediate care. His intellect was perfect, but the power of speech was almost entirely extinct. He could still pronounce the vowels a, e, and i, but o and u, as well as the consonants b, d, 7c, l, p, t were beyond his powers of articulation. In spite of constant elec- trization by M. Duchenne, the paralysis increased, and even- tually, during the early part of the present month, the patien died of starvation. Paris, Feb. 2nd, 1863. THE ALLEGED CONSULTATION WITH A HOMŒOPATHIST AT BEDFORD. Up to the time of our going to press, we had received no, explanation from Dr. Wharton with respect to the statement made by his colleague, Mr. Sharpin, in the last number of this journal. Dr. Burrows may plead ignorance of the "anteee- dents" " of his former pupil, but Dr. Wharton is not in a cono dition to shelter himself under such an excuse. Medical News. APOTHECARIES’ HALL.-The following gentlemen passed their examination in the Science and Practice of Medicine, aDd received certificates to practise, on the 29th ult. :- Brittain, Thomas Lewis, Chester. Ellis, Heleir Dowling, St. Bartholomew’s Hospital. Gray, Frederick John, March, Isle of Ely. Handley, Joseph, King-street, Oldham. Johnson, James Mercer, Everton, Liverpool. Lyman, John, Guy’s Hospital. Mann, John Dixon, Westview, Kendal. Matthews, James, Cowes, Isle of Wight. Miller, John Nicholas, The Square, Hampstead. Patrick, Samuel Alex., Tipping-street, Manchester. The following gentlemen passed the Preliminary Examina- tion in Arts at the Hall on the 30th and 31st ult. :- Burge, Frederick John, Hammersmith. Bntlin, Henry Trensham, Camborne. Davies, Nathaniel Edward, Billesdon. Donalioo, Thomas Bradford, London. Drew, Alfred Stanbank, Stow-on-the-Wold. Farwell, James W. G., St. George’s Hospital. Flower, Thomas, Middlesex Hospital. Hickman, Richard MurhalJ, Shrewsbury. Hughes, J. B., Congleton. Hull, George Askew, Kensington. Peacock, Stanley, London. Kichardson, Charles, Gomersal. Sankey, Julius Ottaway, Witney. Waters, John H., :vottingham. Worthington, James C., Lowestoft.
Transcript of MEDICAL TRIALS
161
drug. I have found the most efficacious to be, an infusion of from half a drachm to a drachm of the powder, and repeated, ifnecessary, in twenty minutes, with the addition of one tea- spoonful of brandy-and-sugar. In this way I have seldom seeneven the approach to sickness; but have ALWAYS been re-
warded by a safe and speedy termination of my patient’ssufferings.
Surely, then,,Dr. Hewitt will agree with me, to carry thisquestion further than he has done. The cause is a righteousone, and deserving our deepest interest. He will, I am sure,pardon my zeal on these interesting points, and the divergenceof opinion which exists. It is by these means only that wecan arrive at just conclusions; and with so much at stake-thesuffering female in our hands-I feel persuaded that only onemotive can actuate all.
I am. Sir. vours faithfullv.WM. SETH GILL, L.R.C.P.Pentonville, Feb. 1863.
MEDICAL TRIALS.
GUILDHALL, FRIDAY, JAN. 30TH.
Sittings at Nisi Prius.(Before Mr. Justice BYLES and a Common Jury.)
TURNER AND ANOTHER V. REYNELL.
Mr. Mills, Q.C., and Mr. Marshall Griffith were for the plaintiffs ; and Mr. Lopez was for the defendant.The plaintiffs are surgeons carrying on business in Phillimore-
place, and the defendant is an attorney carrying on business inStaple-inn. This action was brought to recover the amount ofthe plaintiffs’ bill for medical attendance on the defendant’sfamily, and especially on his wife, who was afflicted with anervous malady. The plaintiffs having sent in their account,the defendant wrote to say that he could not afford to pay solarge a demand, and contrasted their bill with that of previousmedical men who had attended his family. Some correspond-ence ensued, but no settlement was effected, and no moneypaid into court.The plaintiff Turner, having proved his case, was cross ex-
amined as to the date of his registry, and that of his partner,and it was objected that Mr. Smith, one of the plaintiffs, wasnot registered at the time of the performance of the servicessued for, although he had been registered since. On this pointthe learned judge said he was against the defendant. The nextobjection was that Mr. Turner and Mr. Smith did not enterinto partnership until the 29th of September, and it was ruledthat the plaintiffs could only recover jointly on that portion ofthe bill which had been contracted since that date ; for theprevious portion of the bill another action must be brought. Itwas next urged that the plaintiffs, being surgeons, could onlyrecover for surgical operations, such as galvanizing Mrs. Rey.nell, and syringing the defendant’s ears, not having a certifi-cate from the Apothecaries’ Hall.Mr. Justice BYLES remarked: Then, supposing a surgeon and
an apothecary to be in partnership, they cannot recover forsurgical items in their bill, because one of them is an apothe-cary ; neither can they recover for medicine and attendance,because one of them is a surgeon.In the end a verdict was entered for the plaintiffs for
£46 13s. 6d., with leave to move on points of law raised, theCourt to have power to make all the requisite amendments,and to grant all needful certificates to entitle the plaintiffs tctheir costs.
PARISIAN MEDICAL INTELLIGENCE
(FROM OUR SPECIAL CORRESPONDENT.)
I MENTIONED some months ago, when speaking of thevarious contributions made to pathology by Dr. Duchenne of
Boulogne, that he in 1860 drew attention to a particular formof progressive muscular paralysis-that of the tongue, soft
palate, and lip-which had previously escaped attention, orhad not, at all events, been recognised as a distinct morbidspecies. M. Trousseau, in a recent clinical lecture at theHôtel Dieu, has endorsed all Dr. Duchenne’s views, corrobo-rated the exactitude of his observations, and accepted the newmalady defined by this zea’lous investigator as a bona,fide addi-tion to the nosological catalogue. " I saw examples of this
- - - --
disease," said M. Trousseau, " so early as the year 1841, with-out, however, I must confess, recognising its peculiar charac.teristics. I consequently feel that I have no share in a discoverywhich entirely belongs to Dr. Duchenne, and to this gentlemanattaches the credit of having in 1860 called the attention ofpathologists to this particular kind of paralysis. On the 4thof June last an example of this form of disease fell under mynotice in the case of a printer, aged sixty-two, who was ad-mitted into the Hotel Dieu. This man, of a good constitutionand regular habits, in the month of March, 1862, perceived forthe first time some difficulty in pronouncing and articulatingwords. A month later a new symptom was added to the first.He found that during his meals the food was apt to collectbetween the teeth and the cheeks, and rendered the use of thefinger necessary in order to bring the food back between theteeth, the tongue no longer performing this office. Moreover,the saliva was apt to collect in the mouth, and required to befrequently ejected. In this state the patient first came undermy notice. There existed a paralysis of the orbicularis oris,and an almost complete absence of the power of speech, notfrom any laryngeal defect, but from paralysis of the lips andtongue. None of the muscles of the face, except the orbicu-laris, were affected. The tone of the voice was nasal, due nodoubt to defective muscular power in the soft palate. Theswallowing of solid and liquid food could be effected at will, asalso the deglutition of the saliva ; but the intervention of theact of volition was necessary on each occasion. The instinctivedeglutition by which the mouth when full of saliva is in thenormal state emptied, had ceased to occur." This symptom,according to M. Duchenne, belongs to an early period of themalady. After having passed the summer in the wards of M.Empis, the patient fell under M. Trousseau’s immediate care.His intellect was perfect, but the power of speech was almostentirely extinct. He could still pronounce the vowels a, e,and i, but o and u, as well as the consonants b, d, 7c, l, p, t werebeyond his powers of articulation. In spite of constant elec-trization by M. Duchenne, the paralysis increased, and even-tually, during the early part of the present month, the patiendied of starvation.
Paris, Feb. 2nd, 1863.
THE ALLEGED CONSULTATION WITH AHOMŒOPATHIST AT BEDFORD.
Up to the time of our going to press, we had received no,explanation from Dr. Wharton with respect to the statementmade by his colleague, Mr. Sharpin, in the last number of thisjournal. Dr. Burrows may plead ignorance of the "anteee-dents" " of his former pupil, but Dr. Wharton is not in a conodition to shelter himself under such an excuse.
Medical News.APOTHECARIES’ HALL.-The following gentlemen passed
their examination in the Science and Practice of Medicine, aDdreceived certificates to practise, on the 29th ult. :-
Brittain, Thomas Lewis, Chester.Ellis, Heleir Dowling, St. Bartholomew’s Hospital.Gray, Frederick John, March, Isle of Ely.Handley, Joseph, King-street, Oldham.Johnson, James Mercer, Everton, Liverpool.Lyman, John, Guy’s Hospital.Mann, John Dixon, Westview, Kendal.Matthews, James, Cowes, Isle of Wight.Miller, John Nicholas, The Square, Hampstead.Patrick, Samuel Alex., Tipping-street, Manchester.
The following gentlemen passed the Preliminary Examina-tion in Arts at the Hall on the 30th and 31st ult. :-
Burge, Frederick John, Hammersmith.Bntlin, Henry Trensham, Camborne.Davies, Nathaniel Edward, Billesdon.Donalioo, Thomas Bradford, London.Drew, Alfred Stanbank, Stow-on-the-Wold.Farwell, James W. G., St. George’s Hospital.Flower, Thomas, Middlesex Hospital.Hickman, Richard MurhalJ, Shrewsbury.Hughes, J. B., Congleton.Hull, George Askew, Kensington.Peacock, Stanley, London.Kichardson, Charles, Gomersal.Sankey, Julius Ottaway, Witney.Waters, John H., :vottingham.Worthington, James C., Lowestoft.
