Medical Histology Laboratory

Stephen Ernst, Ph.D.

Integumentary System

EpidermisEpidermis

DermisDermis

HypodermisHypodermis Sweat GlandsSweat Glands

TendonTendon

Skeletal MuscleSkeletal Muscle

Blood VesselsBlood Vessels

Slide 112 SkinSlide 112 Skin

FATFAT

Dermal PapillaeDermal Papillae

Epidermal RidgesEpidermal Ridges

Reticular DermisReticular Dermis

Papillary DermisPapillary DermisComponentsOf DermisComponentsOf Dermis

St. Basale (B)St. Basale (B)

St. Spinosum (S)St. Spinosum (S)

St. Granulosum (G)St. Granulosum (G)

St. Corneum (C)St. Corneum (C)

Components of EpidermisComponents of Epidermis

CC

GG

SS

BB

NerveNerve

Blood VesselsBlood Vessels

CTCT

NOTE: Presence of nuclei here is abnormalNOTE: Presence of nuclei here is abnormal

Meissner’sCorpuscle inpapilla

Meissner’sCorpuscle inpapilla

Basement MembraneBasement Membrane

Dermal PapillaDermal Papilla

Meissner’sCorpuscleMeissner’sCorpuscle

Slide 180: Meissner’s CorpuscleSlide 180: Meissner’s Corpuscle

FlattenedSchwann CellLaminae encasing nervefiber endings

FlattenedSchwann CellLaminae encasing nervefiber endings

DermisDermis

HypodermisHypodermis

Nerve FasiclesNerve Fasicles

Secretory PortionsSecretory Portions

SecretoryDuctsSecretoryDucts

Sweat GlandsSweat Glands

Blood VesselsBlood Vessels

Myoepithelial ProcessesMyoepithelial ProcessesMyoepithelial NucleiMyoepithelial Nuclei

PacinianCorpusclePacinianCorpuscle

(multilayeredcapsule surrounding central nerve fiber)

(multilayeredcapsule surrounding central nerve fiber)

Slide 180: finger tipSlide 180: finger tip

EpidermisEpidermis

DermisDermisHypodermisHypodermis

Slide 108: finger tipSlide 108: finger tipDermisDermis

HypodermisHypodermis

Pacinian CorpusclesPacinian Corpuscles

Slide 42 MesenterySlide 42 Mesentery

PacinianCorpusclePacinianCorpuscle

NerveNerve

MelanocytesMelanocytes

Melanin granulesMelanin granules

105-1 Thin Skin105-1 Thin Skin

105-2105-2

External Root SheathExternal Root Sheath

Sebaceous Gland(Holocrine Secretion) Sebaceous Gland(Holocrine Secretion)

Eccrine Sweat GlandsEccrine Sweat Glands

Arrector Pili muscleArrector Pili muscle

Hair BulbHair BulbConnective Tissue (Dermal) PapillaConnective Tissue (Dermal) Papilla

Hair Shaft Canal

Hair Shaft Canal

107 Hair Follicle107 Hair Follicle

??

Slide 109-1 Apocrine GlandsSlide 109-1 Apocrine Glands

Myoepithelial Cell

Processes

Myoepithelial Cell

Processes

Myoepithelial CellsMyoepithelial Cells

ApicalSecretoryGranules

ApicalSecretoryGranules

Apocrine Glands Slide 104-2Apocrine Glands Slide 104-2

Slide 109-2 Apocrine Sweat Glands Slide 109-2 Apocrine Sweat Glands (PAS Stain for glycoproteins, mucins, etc.)(PAS Stain for glycoproteins, mucins, etc.)

Secretory GranulesSecretory Granules

Myoepithelial CellsMyoepithelial Cells

Basement MembraneBasement Membrane

Slide 265 Nipple and AreolaSlide 265 Nipple and Areola

Lactiferous DuctsLactiferous DuctsSebaceous

GlandsSebaceous

Glands

Smooth Muscle Fasicles

Smooth Muscle Fasicles

Duct opening to surfaceDuct opening to surface

Slide 259: Inactive Mammary GlandSlide 259: Inactive Mammary Gland

Interlobular Connective Tissue

Interlobular Connective Tissue

IntralobularConnectiveTissue

IntralobularConnectiveTissue

DuctsDucts

Ductal Cellslining lumenDuctal Cellslining lumen

2nd layer ofMyoepithelialCells

2nd layer ofMyoepithelialCells

Slide 258: Active Mammary GlandSlide 258: Active Mammary Gland

Interlobular CTInterlobular CT

ExcretoryDuctExcretoryDuct

Secretory Alveoli in Glandular Lobules

Secretory Alveoli in Glandular Lobules

(Ductal plus Myoepithelial Cells)(Ductal plus Myoepithelial Cells)