MBV2010/BIO2140 Colloquium, March 6. RULES Multiple choice Only one correct answer 30-60 seconds to...

MBV2010/BIO2140

Colloquium, March 6

RULES

• Multiple choice• Only one correct answer• 30-60 seconds to answer• No textbook, computer, mobile phone, please

There will be a prize for the group with the most correct answers.

Which of the following statements is wrong?

A Uracil is a pyrimidine base

B Virus genomes can have a size of more than 2 million bp

C Cytosine is often methylated in DNA

D Some bacteriophages are retroviruses

1

?

Which of the following statements is wrong?

A Uracil is a pyrimidine base

B Virus genomes can have a size of more than 2 million bp

C Cytosine is often methylated in DNA

D Some bacteriophages are retroviruses

1

Which of the following systems repairsDNA mismatches?

A RBCD

B MutSLH

C UvrABC

D DNA glycosylases

2

DNA glycosylases are involved in

A Base excision repair

B Nucleotide excision repair

C Direct repair of damaged bases

D Repair of double strand breaks

3

Which of the following DNA polymerasessynthesizes DNA in a template-independent manner?

A DNA polymerase I

B DNA polymerase III

C DNA polymerase IV

D DNA polymerase ß

4

Most histone tail modifications occur on

A Histone H2A

B Histone H2B

C Histone H3

D Histone H4

5

Pairing of homologous chromosomes in meiosisis mediated by

A Cohesins

B Condensins

C Homologous recombination

D Cyclins

6

TRF2 is a protein that binds to

A Centromeres

B Replication forks

C Telomeres

D Origins of replication

7

Which of the following proteins resolves Holliday junctions?

A RuvA

B RuvB

C RecA

D Rad51c

8

Which of the following proteins resolves Holliday junctions?

A RuvA

B RuvB

C RecA

D Rad51c

8

Rad51c

Rad51c and other eukaryotic proteinsfunction like RuvC in E. coli

Which protein initiates homologousrecombination in meiosis?

A Spo11

B Dmc1

C MRX

D Rad51

9

Spo11 is a

A serine recombinase

B transposase

C type II topoisomerase

D type I topoisomerase

10

What proteins are shown in this figure?

A Xis and IHF

B Xis and integrase

C Integrase and IHF

D none of the above

11

What proteins are shown in this figure?

A Xis and IHF

B Xis and integrase

C Integrase and IHF

D none of the above

11IHF

The molecular weight of histones is between12

A 11 – 21 kD

B 6 – 12 kD

C 20 – 25 kD

D 28 – 35 kD

The molecular weight of histones is between

A 11 – 21 kD

B 6 – 12 kD

C 20 – 25 kD

D 28 – 35 kD

12

What are the most abundant transposonsin the human genome?

13

A PolyA retrotransposons

B DNA transposons

C Endogenous retroviruses

D LTR retrotransposons

Which proteins are shown in this figure?14

A RuvA (1) and RuvB (2)

B RuvA (2) and RuvB (1)

C RuvA (1) and RuvC (2)

D RuvB (1) and RuvC (2)

1 2

The yellow protein in this figure is15

A a DNA topoisomerase

B a DNA polymerase

C a DNA helicase

D a primase

Insertion (IS) sequences are16

A LINE retrotransposons

B DNA transposons

C LTR retrotransposons

D SINE retrotransposons

Which genome contains Ty transposons?17

A Human

B Drosophila

C Yeast

D E. coli

All transposons18

A contain terminal repeats

B contain a reverse transcriptase

gene

C contain at least one gene

D are flanked by target site

duplications

MBV2010/BIO2140 Colloquium, March 6. RULES Multiple choice Only one correct answer 30-60 seconds to...

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