Malaria
2
The adult dose of Malarone ® by mouth is: 4 (‘standard’) tablets once daily for 3 days. The dose of Riamet ® by mouth for adult with bodyweiht o!er 3" # is: 4 tablets initially$ followed by " further doses of 4 tablets each i!en at %$ &4$ 3'$ 4%$ and ' hours (total &4 tablets o!er ' hours). arenteral. *f the +atient is seriously ill or unable to ta#e tablets$ or if more than & , of red blood cell are +arasiti-ed$ uinine should be i!en by intra!enous infusion /unlicensed0. The adult dosae reimen for uinine by infusion is: loadin dose & of & m1# 3 (u+ to ma2imum .4 ) of uinine salt infused o!er 4 hours then % hours after the start of the loadin dose$ maintenance dose of m1# 4 (u+ to ma2imum m) of uinine salt infused o!er 4 hours e!ery % hours (until +atient can swallow tablets to com+lete the 5day . 6alid for uinine hydrochloride$ dihydrochloride$ and sulfate7 not !alid for uinine bisulfate which
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Transcript of Malaria
The adult dose of Malarone by mouth is:4 (standard) tablets once daily for 3 days.The dose of Riamet by mouth for adult with bodyweight over 35 kg is:4 tablets initially, followed by 5 further doses of 4tablets each given at 8, 24, 36, 48, and 60 hours(total 24 tablets over 60 hours).Parenteral. If the patient is seriously ill or unable totake tablets, or if more than 2 % of red blood cell areparasitized, quinine should be given by intravenousinfusion [unlicensed]. The adult dosage regimen forquinine by infusion is:loading dose2 of 20 mg/kg3 (up to maximum 1.4 g)of quinine salt1 infused over 4 hours then 8 hoursafter the start of the loading dose, maintenance doseof 10 mg/kg4 (up to maximum 700 mg) of quininesalt1 infused over 4 hours every 8 hours (untilpatient can swallow tablets to complete the 7-day1. Valid for quinine hydrochloride, dihydrochloride, andsulfate; not valid for quinine bisulfate which
