Lipid. The function of lipid Lipids are a class of biological molecules defined by low solubility in...
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Transcript of Lipid. The function of lipid Lipids are a class of biological molecules defined by low solubility in...
The function of lipidThe function of lipid Lipids are a class of biological molecules defined by low solubility in water and high
solubility in nonpolar solvents.
Function:
Energy
membrane
5.· Fatty Acids5.· Fatty Acids
Fatty acids are either saturated (all carbon-carbon bonds are single bonds) or unsaturated
(with one or more double bonds in the hydrocarbon chain). If a fatty acid has a single double bond, it is said to be monounsaturated, and if it has more than one, polyunsaturated.
A list of the most abundant fatty acids (M table 10.1)A list of the most abundant fatty acids (M table 10.1)
Glycerophospholipids Glycerophospholipids
A 1,2-diacylglycerol that has a phosphate group esterified at carbon atom 3 of the
glycerol backbone is a glycerophospholipid, also known as a phosphoglyceride or a
glycerol phosphatide
The Most Common The Most Common Phospholipids Phospholipids
Phosphatidic acidPhosphatidic acid
phosphatidyleth-phosphatidyleth- anolamine,anolamine, is is diphosphatidylglyceroldiphosphatidylglycerol
Structures of several glycerophospholipids and space-filling models of phosphatidylcholine, phosphatidylglycerol, and phosphatidylinositol.
GlycerophospholipidGlycerophospholipid Degradation:Degradation:
One of the Effects of Snake Venoms The venoms of poisonous snakes contain (among
other things) a class of enzymes known as phospholipases, enzymes that cause the
breakdown of phospholipids.
Ether Glycerophospholipids Ether Glycerophospholipids
Ether glycerophospholipids possess an ether linkage instead
of an acyl group at the C-1 position of glycerol
The structure of 1-alkyl 2-acetyl-phosphatidylcholine, also known as
platelet activating factor or PAF
Sphingolipids often a hydrocarbon R group is Sphingolipids often a hydrocarbon R group is attached to the NHattached to the NH22 as in ceramide as in ceramide
Separation and analysis of lipidSeparation and analysis of lipid
Lipid extraction requires organic solvent
Adsorption chromatography separates lipids of different polarity
Gas-Liquid Chromatography resolves mixtures of volatile lipid derivatives
Specific hydrolysis(mild acid or alkaline treatment) aids in determination of lipid
structure
Mass spectrometry reveals complete lipid structure