PROFILE

1 NAME LIM SIONG MENG

2 ACADEMIC POSITION

SENIOR LECTURER

3 STATUS OF APPOINTMENT

PERMANENT

4 CITIZENSHIP MALAYSIAN

5 EDUCATION

PhD (Medicine); University of New South Wales, Australia; Ministry of Higher Education (MOHE) Scholarship; 2008 – 2012

MSc (Oncology); University of Nottingham, UK; Joint Chevening Scholarship; 2002 – 2003

BSc (Biomedical Sciences); Universiti Putra Malaysia; 1999 – 2002

6 WORKING EXPERIENCE

• Senior Lecturer (DM52), Faculty of Pharmacy, Universiti Teknologi MARA, Puncak Alam Campus, Selangor Branch, 1 March 2013 – present

• Lecturer (DM45), Faculty of Pharmacy, Universiti Teknologi MARA, Shah Alam Campus, 1 March 2005 – 2 8 February 2013

7 CURRENT ACADEMIC RESPONSIBILITIES

MSc

• NRS714: Applied Pharmacology in Nursing BSc/ BPharm • OPT476: General Pharmacology • PHC427: Principles of Pharmacology & Medicinal Chemistry • PHC452: Peripheral Nervous System &

Pharmacotherapeutics • PHC472: Infectious Diseases & Pharmacotherapeutics • PHC473: Endocrine, Reproductive Systems and

Pharmacotherapeutics • PHC502: Respiratory & Renal Systems &

Pharmacotherapeutics • PHC503: Cardiovascular System & Pharmacotherapeutics • PHC527: Toxicology • PHC553: Cancer Chemotherapeutics • PHC566: Research I • PHC567: Research II

8 RESEARCH INTERESTS/ PROJECTS

• Functional food (probiotics and their beneficial effects)

• Drug discovery (anti-angiogenic, anticancer, antimicrobial and neuroprotective agents, nutraceuticals)

• Therapeutic targets (cancer, Alzheimer’s disease and Parkinson’s disease, metabolic diseases)

9 PUBLICATIONS

INDEXED JOURNALS Google Scholar: H-Index = 11; Citations = 434 https://scholar.google.com/citations?user=Dj9HBjUAAAAJ&hl=en Scopus: H-Index = 9; Citations = 234 https://www.scopus.com/authid/detail.uri?origin=cto&authorId=57194562137&zone=&origin=cto 1. Sumit Tahlan, Balasubramanian Narasimhan, Siong Meng

Lim, Kalavathy Ramasamy, Vasudevan Mani, Syed Adnan Ali Shah (2018) 2-Mercaptobenzimidazole Schiff Bases: Design, Synthesis, Antimicrobial Studies and Anticancer Activity on HCT-116 Cell Line. Mini-Reviews in Medicinal Chemistry. DOI: 10.2174/1389557518666181009151008 (Epub Abstract Ahead of Print/ IF = 2.645/ ISI/ Q2)

2. Sumit Tahlan, Balasubramanian Narasimhan, Siong Meng Lim, Kalavathy Ramasamy, Vasudevan Mani and Syed Adnan Ali Shah (2018) Design, Synthesis, SAR Study, Antimicrobial and Anticancer Evaluation of Novel 2-Mercaptobenzimidazole Azomethine Derivatives. Mini-Reviews in Medicinal Chemistry https://doi.org/10.2174/1389557518666180903151849 (Epub Ahead of Print/ IF = 2.645/ ISI/ Q2)

3. Harmeet Kaur, Siong Meng Lim, Kalavathy Ramasamy, Mani Vasudevan, Syed Adnan Ali Shah, and Balasubramanian Narasimhan (2017) Diazenyl Schiff Bases: Synthesis, Spectral Analysis, Antimicrobial studies and Cytotoxic Activity on Human Colorectal Carcinoma Cell Line (HCT-116). Arabian Journal of Chemistry (In Press/ IF = 4.553/ ISI/ Q2)

4. Sanjiv Kumar, Balasubramanian Narasimhan, Siong Meng Lim, Kalavathy Ramasamy, Vasudevan Mani, Syed Adnan Ali Shah (2019) Design, Synthesis and Biological Potential of 5-(2-Amino-6-(3/4-bromophenyl) pyrimidin-4-yl) benzene-1,3-diol Scaffolds as Promising Antimicrobial and Anticancer agents. Mini-Reviews in Medicinal Chemistry, 19(10), 851-864 (IF = 2.645/ ISI/ Q2)

5. Deepika Sharma, Sanjiv Kumar, Balasubramanian Narasimhan, Kalavathy Ramasamy, Siong Meng Lim, Syed Adnan Ali Shah and Vasudevan Mani (2019) 4-(4-Bromophenyl)-thiazol-2-amine derivatives: synthesis, biological activity and molecular docking study with ADME profile. BMC Chemistry, 13:60

https://doi.org/10.1186/s13065-019-0575-x (IF = 2.284/ ISI/ Q2)

6. Sumit Tahlan, Sanjiv Kumar, Kalavathy Ramasamy, Siong Meng Lim, Syed Adnan Ali Shah, Vasudevan Mani, Ranjana Pathania and Balasubramanian Narasimhan (2019) Design, synthesis and biological profile of heterocyclic benzimidazole analogues as prospective antimicrobial and antiproliferative agents. BMC Chemistry, 13:50 https://doi.org/10.1186/s13065-019-0567-x (IF = 2.284/ ISI/ Q2)

7. Deepika Sharma, Sanjiv Kumar, Balasubramanian Narasimhan, Kalavathy Ramasamy, Siong Meng Lim, Syed Adnan Ali Shah and Vasudevan Mani (2019) Synthesis, molecular modelling and biological significance of N-(4-(4-bromophenyl) thiazol-2-yl)-2-chloroacetamide derivatives as prospective antimicrobial and antiproliferative agents. BMC Chemistry, 13:46 https://doi.org/ 10.1186/s13065-019-0564-0 (IF = 2.284/ ISI/ Q2)

8. Sanjiv Kumar, Balasubramanian Narasimhan, Siong Meng Lim, Kalavathy Ramasamy, Vasudevan Mani and Syed Adnan Ali Shah (2019) Design, Synthesis and Therapeutic Potential of Some 6, 6'-(1,4- phenylene)bis(4-(4-bromophenyl)pyrimidin-2-amine) analogues. Mini-Reviews in Medicinal Chemistry, 19(7), 609-621 (IF = 2.645/ ISI/ Q2)

9. Sumit Tahlan, Kalavathy Ramasamy, Siong Meng Lim, Syed Adnan Ali Shah, Vasudevan Mani and Balasubramanian Narasimhan (2019) 4-(2-(1H-Benzo[d]imidazol-2-ylthio)acetamido)-N-(substituted phenyl)benzamides: design, synthesis and biological evaluation. BMC Chemistry, 13:12 https://doi.org/10.1186/s13065-019-0533-7 (IF = 2.284/ ISI/ Q2)

10. Rohawi Nur Syakila, Siong Meng Lim, Snezana Agatonovic-Kustrin, Fei Tieng Lim, Kalavathy Ramasamy (2019) In vitro assessment of pediococci- and lactobacilli-induced cholesterol-lowering effect using digitally enhanced high-performance thin-layer chromatography and confocal microscopy. Analytical and Bioanalytical Chemistry, 411(6), 1181-1192 (IF = 3.307/ ISI/ Q1)

11. Sumit Tahlan, Kalavathy Ramasamy, Siong Meng Lim, Syed Adnan Ali Shah, Vasudevan Mani and Balasubramanian Narasimhan (2018) Design, synthesis and therapeutic potential of 3‑(2‑(1H‑benzo[d]imidazol‑2‑ylthio)acetamido)‑N‑(substituted phenyl)benzamide analogues. Chemistry Central Journal, 12: 139. https://doi.org/10.1186/s13065-018-0513-3 (IF =

2.442/ ISI/ Q2) 12. Saloni Kakkar, Sanjiv Kumar, Siong Meng Lim, Kalavathy

Ramasamy, Vasudevan Mani, Syed Adnan Ali Shah and Balasubramanian Narasimhan (2018) Design, synthesis and biological evaluation of 3-(2-aminooxazol-5-yl)-2H-chromen-2-one derivatives. Chemistry Central Journal, 12:130, https://doi.org/10.1186/s13065-018-0499-x (IF = 2.442/ ISI/ Q2)

13. Nor Faizatul F. Ismail, Chin Fen Neoh, Qi Ying Lean, Amir H. Abdullah, Siong Meng Lim, Kalavathy Ramasamy, Rahul P. Patel, Long Chiau Ming (2018) Facial candling for the treatment of allergic rhinitis in young adults: A qualitative study. Journal of Pharmacy and Bioallied Sciences 10 (4), 199-207 (Scopus/ Q2)

14. Neelam Vashist, Surinder Singh Sambi, Balasubramanian Narasimhan, Sanjiv Kumar, Siong Meng Lim, Syed Adnan Ali Shah, Kalavathy Ramasamy and Vasudevan Mani (2018) Synthesis and biological profile of substituted benzimidazoles. Chemistry Central Journal, 12:125 https://doi.org/10.1186/s13065-018-0498-y (IF = 2.442/ ISI/ Q2)

15. Shubham Kashyap, Sanjiv Kumar, Kalavathy Ramasamy, Siong Meng Lim, Syed Adnan Ali Shah, Hari Om and Balasubramanian Narasimhan (2018) Synthesis, biological evaluation and corrosion inhibition studies of transition metal complexes of Schiff base. Chemistry Central Journal, 12:117 https://doi.org/10.1186/s13065-018-0487-1 (IF = 2.442/ ISI/ Q2)

16. Sanjiv Kumar, Jagbir Singh, Balasubramanian Narasimhan, Syed Adnan Ali Shah, Siong Meng Lim, Kalavathy Ramasamy and Vasudevan Mani (2018) Reverse pharmacophore mapping and molecular docking studies for discovery of GTPase HRas as promising drug target for bis-pyrimidine derivatives. Chemistry Central Journal, 12:106 https://doi.org/10.1186/s13065-018-0475-5 (IF = 2.442/ ISI/ Q2)

17. Latifah Robbaniyyah Hassan, Amalina Mohd Tajuddin, Hadariah Bahron, Kalavathy Ramasamy and Siong Meng Lim (2018) Synthesis and characterization of benzohydroxamic acid metal complexes and their cytotoxicity study. Jurnal Teknologi, 80(6), 87-94 (Scopus/ Q3)

18. Saloni Kakkar, Sanjiv Kumar, Balasubramanian Narasimhan, Siong Meng Lim, Kalavathy Ramasamy, Vasudevan Mani and Syed Adnan Ali Shah (2018) Design, synthesis and biological potential of heterocyclic benzoxazole scaffolds as

promising antimicrobial and anticancer agents. Chemistry Central Journal, 12:96 https://doi.org/10.1186/s13065-018-0464-8 (IF = 2.442/ ISI/ Q2)

19. Ismail M. Fareez, Siong Meng Lim, Nurul Aida Ashyqin Zulkefli, Rakesh K. Mishra and Kalavathy Ramasamy (2018) Cellulose derivatives enhanced stability of alginate-based beads loaded with Lactobacillus plantarum LAB12 against low pH, high temperature and prolonged storage. Probiotics and Antimicrobial Proteins, 10(3), 543-557 (IF = 2.345/ ISI/ Q3)

20. Saloni Kakkar, Sumit Tahalan, Siong Meng Lim, Kalavathy Ramasamy, Vasudevan Mani, Syed Adnan Ali Shah and Balasubramanian Narasimhan (2018) Benzoxazole Derivatives: Design, Synthesis and Biological Evaluation. Chemistry Central Journal, 12:92 https://doi.org/10.1186/s13065-018-0459- (IF = 2.442/ ISI/ Q2)

21. Siti Solihah Khaidir, Hadariah Bahron, Amalina Mohd Tajuddin, Kalavathy Ramasamy and Siong Meng Lim (2018) High Nuclearity Cu(II) and Co(II) complexes of Schiff Base Derived from o-vanillin with substituted m-phenylenediamine. International Journal of Engineering & Technology, 7 (3.11) 72-76 (Scopus/ Q4)

22. Ismail M. Fareez, Siong Meng Lim and Kalavathy Ramasamy (2018) Microencapsulated Lactobacillus plantarum LAB12 showed no sign of acute or sub-chronic toxicity in vivo. Probiotics and Antimicrobial Proteins doi: 10.1007/s12602-018-9442-7 (IF = 2.345/ ISI/ Q3)

23. Sanjiv Kumar, Siong Meng Lim, Kalavathy Ramasamy, Vasudevan Mani, Syed Adnan Ali Shah and Balasubramanian Narasimhan (2018) Design, synthesis, antimicrobial and cytotoxicity study on human colorectal carcinoma cell line of new 4,4’-(1,4-phenylene)bis(pyrimidin-2-amine) derivatives. Chemistry Central Journal 12:73 https://doi.org/10.1186/s13065-018-0440-3 (IF = 2.442/ ISI/ Q2)

24. N. Zakaria, M.Z. Ramli, K. Ramasamy, L.S. Meng, C.Y. Yean, K.K. Banga Singh, Z.M. Zain, K.-F. Low (2018) An impedimetric micro-immunosensing assay to detect Alzheimer's disease biomarker: Aβ40, Analytical Biochemistry, 555 (2018), 12-21 (IF = 2.334/ ISI/ Q2)

25. Nur Syakila Rohawi, Kalavathy Ramasamy, Snezana Agatonovic-Kustrin and Siong Meng Lim (2018) A new high-performance thin-layer chromatographic method for determining bile salt hydrolase activity. Journal of

Chromatography B, 1092 (2018), 145-151 (IF = 2.603/ ISI/ Q1)

26. Snehlata Yadav; Siong Meng Lim, Kalavathy Ramasamy, Mani Vasudevan, Syed Adnan Ali Shah, Abhishek Mathur, Narasimhan B (2018) Synthesis and evaluation of antimicrobial, antitubercular and anticancer activities of 2-(1-benzoyl-1H-benzo[d]imidazol-2-ylthio)-N-substituted acetamides. Chemistry Central Journal, 12:66, https://doi.org/10.1186/s13065-018-0432-3 (IF = 2.442/ ISI/ Q2)

27. Snehlata Yadav; Narasimhan B, Siong Meng Lim, Kalavathy Ramasamy, Mani Vasudevan, Syed Adnan Ali Shah and Manaikandan Selvaraj (2017) Synthesis, characterization, biological evaluation and molecular docking studies of 2-(1H-benzo[d]imidazol-2-ylthio)-N-(substituted 4-oxothiazolidin-3-yl) acetamides. Chemistry Central Journal, 11:137, https://doi.org/10.1186/s13065-017-0361-6 (IF = 2.442/ ISI/ Q2)

28. Nurul Huda Musa, Vasudevan Mani, Siong Meng Lim, Sharmili Vidyadaran, Abu Bakar Abdul Majeed, Kalavathy Ramasamy (2017) Lactobacilli-fermented cow’s milk attenuated lipopolysaccharide-induced neuroinflammation and memory impairment in vitro and in vivo. Journal of Dairy Research, 84(4), 488-495. (IF = 1.409/ ISI/ Q2)

29. Sanjiv Kumar, Siong Meng Lim, Kalavathy Ramasamy, Mani Vasudevan, Syed Adnan Ali Shah, Manikandan Selvaraj and Balasubramanian Narasimhan (2017) Synthesis, molecular docking and biological evaluation of bis-pyrimidine Schiff base derivatives. Chemistry Central Journal, 11:89 DOI 10.1186/s13065-017-0322-0 (IF = 2.442/ ISI/ Q2)

30. Yuganthini Vijayanathan, Fei Tieng Lim, Siong Meng Lim, Chiau Ming Long, Maw Pin Tan, Abu Bakar Abdul Majeed and Kalavathy Ramasamy (2017) 6-OHDA-lesioned adult zebrafish as a useful Parkinson’s disease model for dopaminergic neuroregeneration. Neurotoxicity Research, 32(3), 496-506. (IF = 2.942/ ISI/ Q1)

31. Nor Faizatul Fatikah Ismail, Chin Fen Neoh, Siong Meng Lim, Amir Heberd Abdullah, Mohd Fahmi Mastuki, Kalavathy Ramasamy, Long Chiau Ming (2017) The Immediate Effect of Facial Candling on Inflammatory Mediators, Substance P, Symptoms Severity and Quality of Life in Allergic Rhinitis Patients: Study Protocol for a Randomised Controlled Trial. Medicine 96(30):e7511 DOI: 10.1097/MD.0000000000007511 (IF = 1.803/ ISI/ Q2)

32. Che Noradlia, Enche Ady, Siong Meng, Lim, Lay Kek, Teh,

Mohd Zaki, Salleh, Ai-Vyrn, Chin, Maw Pin, Tan, Philip, Pooi, Shahrul Bahyah, Kamaruzzaman, Abu Bakar, Abdul Majeed, Kalavathy, Ramasamy (2017) Metabolomic-guided discovery of Alzheimer’s disease biomarkers from body fluid. Journal of Neuroscience Research, 95(10), 2005 - 2024 (IF = 2.481/ ISI/ Q3)

33. Sanjiv Kumar, Siong Meng Lim, Kalavathy Ramasamy, Mani Vasudevan, Syed Adnan Ali Shah and Balasubramanian Narasimhan (2017) Bis-Pyrimidine Acetamides: Design, Synthesis and Biological Evaluation. Chemistry Central Journal, 11:80 DOI 10.1186/s13065-017-0312-2 (IF = 2.442/ ISI/ Q2)

34. Fei Tieng Lim, Siong Meng Lim and Kalavathy Ramasamy (2017) Cholesterol lowering by Pediococcus acidilactici LAB4 and Lactobacillus plantarum LAB12 in adult zebrafish is associated with improved memory and involves an interplay between npc1l1 and abca1. Food & Function, 8, 2817-2828 (IF = 3.247/ ISI/*Joint First Authorship/ Q1)

35. Vasudevan Mani, Siti Murnirah Binti Jaafar, Nur Syamimi Mohd Azahan, Kalavathy Ramasamy, Siong Meng Lim, Long Chiau Ming, Abu Bakar Abdul Majeed (2017) Ciproxifan improves cholinergic transmission, attenuates neuroinflammation and oxidative stress but does not reduce amyloid level in transgenic mice. Life Sciences, 108, 23-35 (IF = 2.936/ ISI/ Q1)

36. Sazereen Md Hasni Dayana, Siong Meng Lim, Ai Vyrn Chin, Maw Pin Tan, Philip Jun Hua Poi, Shahrul Bahyah Kamaruzzaman, Abu Bakar Abdul Majeed, Kalavathy Ramasamy (2017) Peripheral cytokines, C-X-C motif ligand10 and interleukin-13, are associated with Malaysian Alzheimer's disease. Geriatrics & Gerontology International, 17(5), 839-846 (IF = 2.351/ ISI/ Q1)

37. Ismail M. Fareez, Siong Meng Lim, Fei Tieng Lim, Rakesh K. Mishra and Kalavathy Ramasamy (2017) Microencapsulation of Lactobacillus SP. Using Chitosan-Alginate-Xanthan Gum-β-Cyclodextrin and Characterization of its Cholesterol Reducing Potential and Resistance Against pH, Temperature and Storage. Journal of Food Process Engineering, 40(3), e12458, DOI: 10.1111/jfpe.12458 (IF = 1.37/ ISI/ Q2)

38. Ali M. T. M, Zahari H, Aliasak A, Lim S. M, Ramasamy K, Macabeo A. P. G. (2017) Synthesis, Characterization and Cytotoxic Activity of Betulinic Acid and Seco-Betulinic Acid Derivatives against Human Colorectal Carcinoma. Oriental Journal of Chemistry, 33(1), 242-248 (IF = 0.56/ ISI/ Q3)

39. Chin Fen Neoh, Samah Syamimi, Yuet Yen Wong, Mohamed Azmi Ahmad Hassali, Asrul Shafie, Siong Meng Lim, Kalavathy Ramasamy, Yung Wen Han, Nafiza Mat Nasir, Thomas Burroughs (2017) Response: Linguistic and psychometric validation of the Malaysian version of Diabetes Quality of Life-Brief Clinical Inventory (DQoL-BCI): Methodological issues to avoid to misinterpretation. Research in Social and Administrative Pharmacy, 13(4), 884 DOI: 10.1016/j.sapharm.2017.02.004 (IF = 2.196/ ISI/ Q1)

40. Nur Syafiqah Rahim, Siong Meng Lim, Vasudevan Mani and Kalavathy Ramasamy (2017) Enhanced memory in Wistar rats by virgin coconut oil is associated with increased antioxidative, cholinergic activities and reduced oxidative stress. Pharmaceutical Biology, 55 (1), 825-832 (IF = 1.916/ ISI/ Q1)

41. F.T. Lim, S.M. Lim, and K. Ramasamy (2017) Pediococcus acidilactici LAB4 and Lactobacillus plantarum LAB12 assimilate cholesterol and modulate ABCA1, CD36, NPC1L1 and SCARB1 in vitro. Beneficial Microbes, 8(1), 97-109 (IF = 2.923/ ISI/ Q2)

42. Syamimi Samah, Chin Fen Neoh, Yuet Yen Wong, Mohamed Azmi Hassali, Asrul Akmal Shafie, Siong Meng Lim, Kalavathy Ramasamy, Nafiza Mat Nasir, Yung Wen Han, Thomas Burroughs (2016) Linguistic and Psychometric Validation of the Malaysian Version of Diabetes Quality of Life Brief Clinical Inventory (DQoL-BCI). Research in Social and Administrative Pharmacy, http://dx.doi.org/10.1016/j.sapharm.2016.10.017 (IF = 2.196/ ISI/ Q1)

43. Chin Fen Neoh, Chiau Ming Long, Siong Meng Lim, Kalavathy Ramasamy, Suzana Shahar, Abu Bakar Abdul Majeed (2017) Medication use and adherence among multi-ethnic community dwelling older adults in Malaysia. Geriatrics & Gerontology International, DOI: 10.1111/ggi.12849 (IF = 2.351/ ISI/ Q1)

44. Aakash Deep, Balasubramanian Narasimhan, Siong-Meng Lim, Kalavathy Ramasamy, Rakesh Kumar Mishra and Vasudevan Mani (2016) 4-Thiazolidinone derivatives: Synthesis, antimicrobial, anticancer evaluation and QSAR studies. RSC Advances, 6(111), 109485-109494 (IF = 3.108/ ISI/ Q1)

45. E.F. Mohamad Fakri, S.M. Lim, N.H. Musa, M. Hazizul Hasan, A. Adam and K. Ramasamy (2016) Lactobacillus Fermentum Lab 9-Fermented Soymilk with Enriched Isoflavones and Antioxidants Improved Memory In Vivo.

Sains Malaysiana, 45 (9), 1289-1297 (IF = 0.47/ ISI/ Q2) 46. Alia Hamad, Vasudevan Mani, Kalavathy Ramasamy, Siong

Meng Lim and Abu Bakar Abdul Majeed (2016) Memory Enhancement in Rats by Soybean and Tempeh Extracts is Associated with Improved Cholinergic and Reduced Neuroinflammatory Activities. Sains Malaysiana, 45 (9), 1299-1310 (IF = 0.47/ ISI/ Q2)

47. Aakash Deep, Pradeep Kumar, Balasubramanian Narasimhan, Lim Siong Meng, Kalavathy Ramasamy, Rakesh Kumar Mishra, Vasudevan Mani (2016) Synthesis, Antimicrobial and Anticancer Evaluation of 2-Azetidinones Clubbed with Quinazolinone. Pharmaceutical Chemistry Journal, 50 (1), 24 – 28 (IF = 0.445/ ISI/ Q3)

48. Syamimi Samah, Kalavathy Ramasamy, Siong Meng Lim, Chin Fen Neoh (2016) Probiotics for the management of Type 2 Diabetes Mellitus: a systematic review and meta-analysis. Diabetes Research and Clinical Practice, 118, 172-182 (IF = 3.639/ ISI/ Q1)

49. Aakash Deep, Pradeep Kumar, Balasubramanian Narasimhan, Siong Meng Lim, Kalavathy Ramasamy, Rakesh Kumar Mishra and Vasudevan Mani (2016) 2-Azetidinone Derivatives: Synthesis, Antimicrobial, Anticancer Evaluation And Qsar Studies. Acta Poloniae Pharmaceutica, 73 (1), 65 – 78 (IF = 0.745/ ISI/ Q2)

50. Aakash Deep, Pradeep Kumar, Balasubrmanian Narasimhan, Kalavathy Ramasamy, Siong Meng Lim, Vasudevan Mani and Rakesh Kumar Mishra (2016) Synthesis, Antimicrobial, Anticancer Evaluation and Qsar Studies Of Thiazolidin-4-One Derivatives, Acta Poloniae Pharmaceutica, 73 (1), 93 – 106 (IF = 0.745/ ISI/ Q2)

51. Nurhanisah Sejari, Kamaria Kamaruddin, Kalavathy Ramasamy, Siong Meng Lim, Chin Fen Neoh, Long Chiau Ming (2016) The immediate effect of traditional Malay massage on substance P, inflammatory mediators, pain scale and functional outcome among patients with low back pain: Study protocol of a randomised controlled trial. BMC Complementary and Alternative Medicine, 16:16 DOI: 10.1186/s12906-016-0988-1 (IF = 2.288/ ISI/ Q1)

52. Azzeme Harun, Sharmili Vidyadaran, Siong Meng Lim, Anthony L J Cole and Kalavathy Ramasamy (2015) Malaysian endophytic fungal extracts-induced anti-inflammation in lipopolysaccharide-activated BV-2 microglia is associated with attenuation of NO production and, IL-6 and TNF-α expression. BMC Complementary and Alternative Medicine, 15, 166 (IF = 2.288/ ISI/ Q1)

53. Ismail M. Fareez, Siong Meng Lim, Rakesh K. Mishra and Kalavathy Ramasamy (2015) Chitosan coated alginate-xanthan gum bead enhanced pH and thermotolerance of Lactobacillus plantarum LAB12. International Journal of Biological Macromolecules, 72 (2015), 1419-1428. (IF = 3.671/ ISI/ Q1)

54. R K Mishra, K Ramasamy, S M Lim, M F Ismail and A B A Majeed (2014) Antimicrobial and in vitro would healing properties of novel clay based bionanocomposite files. Journal of Materials Science: Materials in Medicine, 25 (8), 1925-1939. (IF = 2.325/ ISI/ Q2)

55. Pooja Rohilla, Aakash Deep, Manju Kamra, Balasubramanian Narasimhan, Kalavathy Ramasamy, Vasudevan Mani, Rakesh Kumar Mishra, Siong Meng Lim (2014) Synthesis, antimicrobial and anticancer evaluation of N’-(substituted benzylidene)-2-(benzo[d]oxazol-3(2H)-yl)aceto hydrazine derivatives. Drug Research, 64 (10), 505-509 (IF = 0.701/ ISI/ Q3)

56. Nurul Aqmar M.N. Hazalin, Siong Meng Lim*, Anthony L.J. Cole, Abu Bakar A. Majeed and Kalavathy Ramasamy (2013) Apoptosis induced by desmethyl-lasiodiplodin is associated with upregulation of apoptotic genes and downregulation of monocyte chemotactic protein-3. Anti-Cancer Drugs, 24 (8), 852-861 (IF = 2.32/ ISI/ *Joint First Authorship/ Q2)

57. Hazalin, N A, Ramasamy, K, Lim, S M, Cole, A L, Majeed, A B. (2012) Induction of apoptosis against cancer cell lines by four ascomycetes (endophytes) from Malaysian rainforest. Phytomedicine, 19 (7), 609-617 (IF = 3.526/ ISI/ Q1)

58. Harun A, Johari James RM, Lim SM, Abdul Majeed AB, Cole AL, Ramasamy K (2011) BACE1 inhibitory activity of fungal endophytic extracts from Malaysian medicinal plants. BMC Complementary and Alternative Medicine, 11 (1), 79 (IF = 2.288/ ISI/ Q1)

59. Kalavathy Ramasamy, Siong Meng Lim, Hamidah Abu Bakar, Noorliana Ismail, Maria Suhana Ismail, Muhamad Fuad Ali, Jean Frederic Faizal Weber, Anthony L. J. Cole (2010) Antimicrobial and Cytotoxic Activities of Malaysian Endophytes. Phytotherapy Research, 24 (5), 640-643 (IF = 3.092/ ISI/ Q1)

60. Nurul Aqmar, M.N.H., Kalavathy, R., Lim, S.M, Ibtisam Abdul Wahab, Weber, J.F.F. and Cole, A.L.J., Abu Bakar Abdul Majeed (2009) Cytotoxic and antimicrobial activities of endophytic fungi isolated from plants at the National Park Pahang. BMC Complementary and Alternative Medicine 9, 46 (IF = 2.288/ ISI/ Q1)

NON-INDEXED JOURNALS 1. Snehlata Yadav, Balasubramanian Narasimhan, Siong M.

Lim, Kalavathy Ramasamy, Mani Vasudevan, Syed A.A. Shah and Abhishek Mathur (2018) Synthesis and evaluation of antimicrobial, antitubercular and anticancer activities of benzimidazole derivatives. Egyptian Journal of Basic and Applied Sciences, 5 (2018), 100-109

BOOK CHAPTERS 1. Sejari N., Kamaruddin K., Neoh C.F., Ramasamy K., Lim

S.M., Ming L.C. (2018) The Effect of Massage and Spinal Manipulation on Substance P: A Narrative Review. In: Yacob N., Mohd Noor N., Mohd Yunus N., Lob Yussof R., Zakaria S. (eds) Regional Conference on Science, Technology and Social Sciences (RCSTSS 2016). Springer, Singapore, 659-665

2. Siong Meng Lim, Muhammad Zaki Bin Ramli, Nor Amalina Ahmad, Vasudevan Mani, Abu Bakar Abdul Majeed and Kalavathy Ramasamy (2015) Probiotics and Neuroprotection. In: Colin R Martin and Victor R Preedy (eds) Diet and Nutrition in Dementia and Cognitive Decline. Elsevier Inc., CA., 859-868

3. Vasudevan Mani, Aliya Ahmad, Kalavathy Ramasamy, Siong Meng Lim, Abu Bakar Abdul Majeed (2015) Murraya koenigii leaves and usage in dementia. In: Colin R Martin and Victor R Preedy (eds) Diet and Nutrition in Dementia and Cognitive Decline. Elsevier Inc., CA., 1039-1048

4. Ramasamy, K., Siong Meng, L., Abdul Wahab, I., Hamzah, M. K. and Abdul Majeed, A. B. (2012). Bioactive endophytic metabolites of selected plants in Taman Negara National Park. In M. N. Suratman, M. S. Daim, H. R. Singh & N. H. Ismail (Eds.), Taman Negara: towards biodiversity conservation and sustainability (pp. 3-12). Shah Alam: UiTM Press.

ABSTRACTS IN JOURNALS 1. Muhamad Fareez Ismail, Lim Siong Meng and Kalavathy

Ramasamy (2019) Alginate-based Microcapsules Facilitate Targeted Release of Lactobacillus plantarum LAB12 in vivo. Frontiers in Pharmacology 10, DOI: 10.3389/conf.fphar.2019.63.00032

2. Faezah Sabirin, Siong Meng Lim, Chin Fen Neoh and Kalavathy Ramasamy (2019) Hepatoprotection by probiotics

in vivo: a systematic review and meta-analysis. Frontiers in Pharmacology 9, DOI: 10.3389/conf.fphar.2018.63.00140

3. Noor Azman Muhammad Syukri, Siong Meng Lim, Fei Tieng Lim and Kalavathy Ramasamy (2019) Lactobacillus plantarum LAB12 enhances cognitive function via modulation of neurotransmitters and neuropeptides in antibiotic- and LPS-challenged rats. Frontiers in Pharmacology 9, DOI: 10.3389/conf.fphar.2018.63.00074

4. Z. M. Zaki, K. Ramasamy, V. Mani and S. M. Lim (2018) F8268-A3-induced Anti-Angiogenicity is mediated, in part, through Downregulation of Vascular Endothelial Growth Factor and Upregulation of Thrombospondin. Asian Journal of Pharmaceutical and Clinical Research, 11(9), 26

5. M. F. Ismail, S. M. Lim and K. Ramasamy (2016) Microencapsulated lactobacillus plantarum LAB12 with excellent heat and storage stability during and after pelletisation. The 4th International Conference on Pharmaceuticals, Nutraceuticals and Cosmetic Sciences (IPNACs), International Journal of Pharmacy and Pharmaceutical Sciences, 8 (2), 19

6. S. M. Lim, N. S. Abdul Rashid, N. Mohd Tahir, S. S. Hasni, S. F. S. Bahrin, M. S. Ibrahim and K. Ramasamy (2016) Cytotoxic and antimicrobial effects induced by ethyl acetate extracts of Malaysian marine endophytic fungi. International Journal of Pharmacy and Pharmaceutical Sciences, 8 (2), 76

7. C. N. A. Enche Ady, S. M. Lim, A-V. Chin, S. B. Kamaruzzaman, M. P. Tan, P. J. H. Poi, L. K. Teh, M. Z. Salleh, I. K. S. Yap, A. B. Abdul Majeed and K. Ramasamy (2016) Serum metabolic profiling of Malaysian Alzheimer’s disease patients unravel perturbed sphingolipid and amino acid pathways. International Journal of Pharmacy and Pharmaceutical Sciences, 8 (2), 110

8. R. M. Zaki, K. Ramasamy and S. M. Lim (2016) RhoA attenuation by pediococcus pentosaceus LAB6 and lactobacillus plantarum LAB12 in neuroblastoma cells is accompanied by amyloid-β inhibition. International Journal of Pharmacy and Pharmaceutical Sciences, 8 (2), 118

9. S. M. H. Dayana, S. M. Lim, A-V. Chin, M. P. Tan, P. J. H. Poi, S. B. Kamaruzzaman, A. B. Abdul Majeed, K. Ramasamy (2016) CXCL10 and CXCR3 mediate neuroinflammation and neuronal cell deaths in Alzheimer’s disease. International Journal of Pharmacy and Pharmaceutical Sciences, 8 (2), 119

10. Z. M. Zaki, K. Ramasamy, V. Mani and S. M. Lim (2016) Differential cytotoxicity of F8268-A3 against MCF7 and MDA468 human breast cancer cells. International Journal of

Pharmacy and Pharmaceutical Sciences, 8 (2), 120 11. S. Samah, C. F. Neoh, Y. Y. Wong, M. A. Hassali, A. A.

Shafie, Y. W. Han, N. Mat Nasir, S. M. Lim and K. Ramasamy (2016) Linguistic and psychometric validation of the Malaysian version of Diabetes Quality of Life Brief Clinical Inventory (DQoL-BCI). International Journal of Pharmacy and Pharmaceutical Sciences, 8 (2), 143

12. SMH Dayana, SM Lim, MP Tan, AV Chin, PJH Poi, K Sharul, ABA Majeed, K Ramasamy (2014) IP-10 and IL-13 as potentially new, non-classical blood-based cytokine biomarkers for Alzheimer’s Disease. Age and Ageing, 43 (Suppl 1), i32.

13. A. Z. Samsudin, K. Ramasamy, S. M. Lim, A. V. Chin, P. J. H. Poi, S. Kamaruzzaman, M. P. Tan and A. B. A. Majeed (2013) Gene expression profiling of peripheral blood identifies MEST, RASSF3, GLYAT, UCP3, IQSEC3 and CKAP4 as potential biomarkers for Alzheimer’s disease. Journal of Science & Technology in the Tropics, Special Issue Supplement, pg S94

14. S. M. H. Dayana, S. M. Lim, M. P. Tan, A. V. Chin, P. J. H. Poi, S. B. Kamaruzzaman, A. B. A. Majeed, K. Ramasamy (2013) Blood-based cytokine profiling of Malaysian Alzheimer’s disease patients. Journal of Science & Technology in the Tropics, Special Issue Supplement, pg S95

15. R. M. Zaki, K. Ramasamy, R. K. Mishra, A. B. A. Majeed and S. M. Lim (2013) Synthesis of starch/ hyaluronic acid films and antimicrobial evaluation against P. aeruginosa, E. coli, S. typhimurium and S. aurues. Journal of Science & Technology in the Tropics, Special Issue Supplement, pg S102

16. Azidah Ali, Siong Meng Lim and Kalavathy Ramasamy (2013) Lactobacillus sp. Isolated from Malaysian fermented food induced apoptosis against human colorectal cancer cells in vitro. Journal of Science & Technology in the Tropics, Special Issue Supplement, pg S114

17. Che Nor Adlia Enche Ady, Chin Ai-Vyrn, Siong Meng Lim, Shahrul Bahyah Kamaruzzaman, Tan Maw Pin, Lay Kek Teh, Mohd Zaki Salleh, Abu Bakar Abdul Majeed, Kalavathy Ramasamy (2013) Serum metabolic profiling of Alzheimer’s disease for early detection. Journal of Science & Technology in the Tropics, Special Issue Supplement, pg S115

18. Hanum Ya’akub, Lim Siong Meng, Vasudevan Mani and Kalavathy Ramasamy (2013) Lactic acid bacteria down-regulating pro-inflammatory cytokines in DSS-induced colitis mice model. Journal of Science & Technology in the Tropics, Special Issue Supplement, pg S117

19. Nor Amalina Ahmad, Siong Meng Lim, Vasudevan Mani, Abu Bakar Abdul Majeed and Kalavathy Ramasamy (2013) Lactobacillus probiotic-induced anti-neuroinflammation in transgenic mice with Alzheimer’s disease was associated with changes of pro- and anti-inflammatory cytokine levels. Journal of Science & Technology in the Tropics, Special Issue Supplement, pg S130

20. Nur Syamimi Mohd Azahan, Vasudevan Mani, Kalavathy Ramasamy, Richard Johari James, Siong Meng Lim and Abu Bakar Majeed (2013) Neuroprotective effects of Mahanimbine in SK-N-SH neuroblastoma cells against LPS-incuded neuroinflammation. Journal of Science & Technology in the Tropics, Special Issue Supplement, pg S149

21. N. S. Rahim, V. Mani, S. M. Lim, N. A. Hazalin and K. Ramasamy (2013) Neuroprotection of virgin coconut oil on memory impaired rat is mediated partly through inflammatory and cholinergic pathways. Journal of Science & Technology in the Tropics, Special Issue Supplement, pg S155

22. I. M. Fareez, S. M. Lim, R. K. Mishra and K. Ramasamy (2013) Microencapsulation of Lactobacillus sp. in chitosan coated alginate-xanthan gum beads enhanced survivability in simulated gastrointestinal condition and heat treatment. Journal of Science & Technology in the Tropics, Special Issue Supplement, pg S158

23. Lim, S. M., Perdomo, J., Galettis, P. and Links, M. (2011). Antiangiogenic effect of low-dose paclitaxel is mediated by RhoA inactivation: A potential new mechanism. In: Proceedings of the AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics; 2011 Nov 12-16; San Francisco, CA. Philadelphia (PA). Mol Cancer Ther, 10(11 Suppl), Abstract nr A4

24. Siong Meng Lim, Nor Hafizah Hassan, Srinivasa R. Jada, Siang Hui Lim, Johnson Stanslas. (2007) Antitumor Activity of SRJ13 Against Estrogen and Non-estrogen Sensitive Breast Cancer Cell Lines. Clinical Cancer Research, 13(22 Suppl), C30

25. Kalavathy R, Lim SM, Abu Bakar H, Ismail N, Ariffin NF, Ismail MS, Weber JFF (2007) Endophytes as a Potential Source of New Anticancer Agents. Clinical Cancer Research, 13(22 Suppl), C30

26. Lua Pei Lin, Wong Tin Wui, Kalavathy Ramasamy, Lim Siong Meng (2007) Flatusorb™: A Unique Flatus Odour Filter for Patients with Excessive Eructation. Malaysian Journal of Medical Sciences, 14 (Suppl 1), ISSN 13-94-195X,

pg 103 27. Lim, S. M., Kalavathy, R., Ismail, M. S. and Othman, N.

(2007) Effects of Malaysian Endophytes on HCT116 (Tumour Type) and WRL68 (Non-Tumour Type) Cell Lines: A Comparison. Malaysian Journal of Medical Sciences, 14 (Suppl 1), ISSN 13-94-195X, pg 213

28. Kalavathy, R., Lim, S. M., Ismail, N. and Ariffin, N. F. (2007) Effect of Malaysian Endophytes on MCF7, A Human Breast Cancer Cell Line. Malaysian Journal of Medical Sciences, 14 (Suppl 1), ISSN 13-94-195X, pg 220

29. SM Lim, J Stanslas and H Ariffin (2006) A Case Study of Precursor B-cell ALL with BCR-ABL Fusion Gene Showed Chemoresistance in vitro. Journal of Oncology Pharmacy Practice, 12 (1), 15

PROCEEDINGS WITH ISSN NUMBER 1. F. Umirah, C. F. Neoh, K. Ramasamy and S. M. Lim (2018)

Inter-Relationship Between Gut Microbiota Composition And Biochemical Profiles In Type 2 Diabetes Mellitus Patients: A Systematic Review. 2018 International Congress of Diabetes and Metabolism, 11-13 October 2018, Grand Hilton Seoul Hotel, Seoul, Korea, ISSN: 2234-4357, Pg 130

2. F. Umirah, C. F. Neoh, K. Ramasamy and S. M. Lim (2018) Differential Gut Microbiota Composition Between Type 2 Diabetes Mellitus Patients And Healthy Individuals: A Systematic Review. 2018 International Congress of Diabetes and Metabolism, 11-13 October 2018, Grand Hilton Seoul Hotel, Seoul, Korea, ISSN: 2234-4357, Pg 161

PROCEEDINGS

International – 53

National – 30

PHD THESES

1. Muhammad Zaki Bin Ramli, Kalavathy Ramasamy, Siong Meng, Lim (Main Supervisor). RhoA Targeting By Probiotics As Strategy To Interfere The Critical Link To Major Hallmarks Of Alzheimer’s Disease, Faculty of Pharmacy, UiTM, 2019

2. Muhamad Fareez Bin Ismail, Siong Meng, Lim (Co-supervisor), Kalavathy Ramasamy. Development Of Thermo-Stable And Ph-Responsive Microencapsulated

Lactobacillus Plantarum LAB12 For Targeted Gut Delivery, Faculty of Pharmacy, UiTM, 2018

MSC THESES

1. Nor Amalina Bt Ahmad Alwi, Kalavathy Ramasamy, Siong Meng, Lim (Main Supervisor). Lactobacillus Plantarum LAB12- and Lactobacillus casei LAB13-induced Neuroprotection was Associated, at Least in Part, with Increased Neurotransmission, Anti-oxidant and Decreased Neuroinflammation in APP Transgenic Mice, Faculty of Pharmacy, UiTM, 2018

2. Che Nor Adlia Bt Enche Ady, Siong Meng, Lim (Co-supervisor), Kalavathy Ramasamy. Serum Metabolic Profiling for Early Detection of Alzheimer’s Disease, Faculty of Pharmacy, UiTM, 2016

3. Nur Syafiqah Bt Rahim, Vasudevan Mani, Nurul Aqmar Mohamad Nor Hazalin, Siong Meng, Lim (Co-supervisor), Kalavathy Ramasamy. Neuroprotective Effect of Virgin Coconut Oil on Lipopolysaccharide-Induced Cell Death in SK-N-SH and Memory Impared in Rat, Faculty of Pharmacy, UiTM, 2015

4. Azidah Binti Ali, Vasudevan Mani, Siong Meng, Lim (Co-supervisor), Kalavathy Ramasamy. Mechanisms underlying anticancer effect of lactobacilli (LAB 12 and LABPC) against human colorectal cancer, Faculty of Pharmacy, UiTM, 2014

5. Ezza Fareesa Binti Mohamad Fakri, Aishah Adam, Siong Meng, Lim (Co-supervisor), Kalavathy Ramasamy. Probiotic fermented soymilk as a dietary antioxidant source and antiproliferative agent, Faculty of Pharmacy, UiTM, 2013

6. Azzeme Bin Harun, Siong Meng, Lim (Co-supervisor), Kalavathy Ramasamy. Inhibitory effects of Malaysian fungal endophytic extracts on BACE1 (β-secretase) and BV2 microglia-mediated inflammatory response, Faculty of Pharmacy, UiTM, 2012

7. Kathleen J Jalani, Siong Meng, Lim (Co-supervisor), Kalavathy Ramasamy, Ibtisam Abdul Wahab. Cytotoxic effect of synthetic stilbenes agaist breast, colon, lung and cancer cell lines, Faculty of Pharmacy, UiTM, 2012

8. Nurul Aqmar Binti Mohamad Nor Hazalin, Siong Meng, Lim (Co-supervisor), Kalavathy Ramasamy. Bioactive endophytic metabolites with antimicrobial and cytotoxic activity of flora sourced from Kuala Keniam and Kuala Trenggan of Taman Negara, Pahang, Faculty of Pharmacy, UiTM, 2010

10 RESEARCH GRANTS

INTERNATIONAL LEVEL 1. IBRO Associate School Workshop, IBRO, 2018,

RM82,000.00, Co-Researcher (Completed) 2. IBRO Associate School Workshop, IBRO, 2016,

RM87,890.00, Co-Researcher (Completed) INDUSTRIAL 1. Gut hormones and anti-inflammatory pathways in probiotics

mediated glycaemic control and improved quality of life, Chr Hansen, Denmark, 2016-2019, In kind probiotics and placebo [6 months; 50 patients (probiotics) + 50 patients (placebo)], Co-Researcher

NATIONAL LEVEL 1. Microbiota-Driven RhoA-Dependent VEGF Pathway

Underlying Lactobacillus plantarum Lab12-Induced Anti-Angiogenicity, FRGS (MOHE), 2017-2020, RM171,720, Principal Investigator

2. VEGF Signaling Cascade Underlying Endophytic Peptides Orchestrated Antiangiogenicity, FRGS (MOHE), 2013-2015, RM123,000, Principal Investigator (Completed)

3. Elucidation of Migratory Pathway-Driven Dopaminergic Neuroregeneration in Teleost-Based Parkinson’s Disease, FRGS (MOHE), 2019-2021, RM170,800, Co-Researcher

4. Elucidation of Brain-Derived Neurotrophic Factor and Neuroimmune Pathways in Cananga odorata Mediated Behaviour Alterations In Patients With Dementia, FRGS (MOHE), 2017-2020, RM155,820, Co-Researcher

5. Dopaminergic Neuroregeneration In Parkinson’s Disease: Missing Links In Wnt Signalling And Beyond, FRGS (MOHE), 2016-2019, RM92,600, Co-Researcher

6. Role Of D-Amino Oxidase Inhibitors As Potential Drugs In The Treatment Of Alzheimer’s Disease: A Proteochemometric Modelling And In Vivo Study , FRGS (MOHE), 2016-2019, RM136,800, Co-Researcher

7. Gut Hormones and Anti-inflammatory Pathways in Probiotics-mediated Glycaemic Control and Improved Quality of Life, FRGS (MOHE), 2014-2018, RM184,500, Co-Researcher (Completed)

8. Mechanism of Ciproxifan Against Cholinergic Deficit-Induced Neuronal Plasticity via Brain-Derived Neurotrophic Factor (BDNF) Signaling Pathway, FRGS (MOHE), 2013-2016, RM150,000, Co-Researcher (Completed)

9. Integrative Systematic Biology in Understanding the Cellular and Molecular Mechanisms of Locally Derived Feed Supplements for Poultry , LRGS (MOHE), 2012-2017, RM2,125,174, Co-Researcher (Completed)

10. AD Blood Biomarkers and Pathway Analysis in the Human Subject: An Integrative-OMICS Approach, LRGS (MOHE),

2012-2016, RM1,145,640, Co-Researcher (Completed) 11. The effect of ear candling on inflammatory mediators and

pain on of allergic rhinitis patients, RAGS (MOHE), 2014-2016, RM80,000, Co-Researcher (Completed)

12. Novel Microbial Metabolites of the National Park Pahang, FRGS (MOHE), 2008-2010, RM50,000, Co-Researcher (Completed)

13. Probiotic Fermented Milk as a Dietary Antioxidant Source and Antiproliferative Agent, E-Science (MOSTI), 2007-2010, RM164,000, Co-Researcher (Completed)

14. Effect of Synthetic Stilbenes against Breast, Lung and Colon Cancer Cell Lines, E-Science (MOSTI), 2007-2010, RM151,400, Co-Researcher (Completed)

15. BACE Inhibitors from Endophytes as Potential Drug against Neurodegeneration of Alzheimer’s Disease, E-Science (MOSTI), 2007-2011, RM200,000, Co-Researcher (Completed)

DANA KECEMERLANGAN UITM 1. Cheminformatics-driven elucidation of the anti-angiogenicity

of F8268, 2016-2018, RM20,000, Principal Investigator (Completed)

2. RhoA targeting by probiotics as strategy to interfere the critical link to major hallmark of Alzheimer's disease, 2016-2017, RM30,000, Principal Investigator (Completed)

3. RhoA targeting by probiotics as strategy to interfere the critical link to major hallmark of Alzheimer's disease, 2014-2015, RM25,600, Principal Investigator (Completed)

4. Novel and smart pH-sensitive 5-FU-loaded hydrogels for targeted drug delivery against colon cancer, 2012-2014, RM32,000, Principal Investigator (Completed)

5. Atheroprotective Effect of Probiotic Lactobacillus plantarum LAB12, 2018-2019, RM25,000, Co-Researcher

6. Biodegraable Nanoparticles Loaded Thermosensative In Situ Gels Of Lomefloxacin Hydrochloride For Sustained Ocular Drug Delivery: In Vitro And In Vivo Evaluation, 2018-2019, RM30,000, Co-Researcher

7. Unravelling The Inter-relationships Between Probiotic-enhanced Gut Microbiota, Glycaemic Control And Systemic Inflammation Among Type 2 Diabetes Patients, 2017-2019, RM50,000, Co-Researcher

8. Unravelling the inter-relationship between glycaemic control and oxidative stress level among diabetes patients upon probiotic intake, 2017-2019, RM20,000, Co-Researcher

9. Unravelling the metabolic signature of probiotics in patients

with Type 2 Diabetes, 2017-2019, RM40,000, Co-Researcher 10. Deciphering the inter-relationships between self-efficacy,

glycaemic control and quality of life among type 2 diabetes patients, 2016-2018, RM20,000, Co-Researcher (Completed)

11. Unravelling the neuroprotective effects of probiotics fermented in soymilk, 2015-2017, RM20,000, Co-Researcher (Completed)

12. Collaborative Drug Discovery Research (CDDR), 2015-2016, RM32,000, Co-Researcher (Completed)

11 AWARDS

INTERNATIONAL LEVEL: 1. Best Poster Presenter. Muhamad Fareez Ismail, Lim Siong

Meng and Kalavathy Ramasamy (2018) Alginate-based Microcapsules Facilitate Targeted Release of Lactobacillus plantarum LAB12 in vivo. The International Conference on Drug Discovery and Translational Medicine 2018 (ICDDTM '18): “Seizing Opportunities and Addressing Challenges of Precision Medicine”, December 3 – 5, 2018, The Everly Hotel, Putrajaya, Malaysia

2. Best Oral Presenter. Z. M. Zaki, K. Ramasamy, V. Mani And S. M. Lim (2018) F8268-A3-induced Anti-Angiogenicity is mediated, in part, through Downregulation of Vascular Endothelial Growth Factor and Upregulation of Thrombospondin. The 1st International Conference on Pharmacy Practice, 27-28 June 2018, Concorde Hotel Shah Alam, OPC4

3. Gold. S. M. Lim, K. Ramasamy, I. M. Fareez, R. M. Zaki and N. A. M. Syukri (2017) G2BTM: Gut-Brain Revitalized! The 28th International Invention, Innovation and Technology Exhibition (ITEX’17), Kuala Lumpur Convention Centre, Malaysia

4. Silver Medal. Z. M. Zaki, N. N. Ban, K. Ramasamy, C. O. Leong and S. M. Lim (2015) ActiPep: A precious gift from nature. The 14th International Conference and Exposition on Inventions by Institutions of Higher Learning (PECIPTA 2015), Kuala Lumpur Convention Centre, Malaysia

5. The University of Western Sydney School of Medicine Award for the best student presentation at the 2012 Australian Society for Medical Research NSW Annual Scientific Meeting, Australian Technology Park, Redfern.

6. 2nd Prize for Oral Presentation. S. M. Lim, J. Perdomo, P. Galettis and M. Links (2011) RhoA inactivation: a potential new mechanism for the antiangiogenic effect of paclitaxel. The St George and Sutherland Hospital Mediacl Research Symposium, The St George Bank Auditorium, Sydney

7. Gold Prize. Lim Siong Meng, Kalavathy Ramasamy, Ammu

Kutty Radhakrishnan and Jean Frederick Faizal Weber (2008) Chemflore: A Potential Novel Proapoptotic Anticancer Agent. The Seoul International Invention Fair (SIIF), Korea

8. Silver Medal. Lim Siong Meng, Kalavathy Ramasamy, Ammu Kutty Radhakrishnan, Anthony Cole and Jean Frederick Faizal Weber (2008) Chemflore: A Potential Novel Proapoptotic Anticancer Agent. The 19th International Invention, Innovation and Technology Exhibition (ITEX), KLCC, Malaysia

9. Gold Medal. Lua Pei Lin, Wong Tin Wui, Kalavathy Ramasamy, Lim Siong Meng (2007) Flatusorb: Flatus Filter. The British Invention Show, UK

10. Silver Medal (Innovation). Lua Pei Lin, Wong Tin Wui, Kalavathy Ramasamy, Lim Siong Meng (2007) Flatusorb™: A Solution to Malodorous Flatus. International Exposition of Research and Invention of Institutions of Higher Learning, KLCC, Malaysia

11. Certificate of Merit (Poster Presentation). Lim, S. M., Kalavathy, R., Ismail, M. S. and Othman, N. (2007) Effects of Malaysian Endophytes on HCT116 (Tumour Type) and WRL68 (Non-Tumour Type) Cell Lines: A Comparison. International Medical Health Congress 2007, USM, Kelantan, Malaysia

NATIONAL LEVEL: 1. Silver Medal. Nor Amalina Ahmad, Muhamad Fareez Ismail,

Lim Siong Meng and Kalavathy Ramasamy (2014) AD-Caps: When gut-brain connects. Malaysia Technology Expo 2014, PWTC, Kuala Lumpur.

2. Bronze Medal (Innovation). Kalavathy Ramasamy, Lim Siong Meng, Hamidah Bt Abu Bakar, Jean Frederic Faizal Weber, Anthony Cole (2007) Kalstevex™ : A New, Potential Local Microbial-derived Antineoplastic Agent. Malaysia Technology Expo 2007, Kuala Lumpur, Malaysia

3. Best Poster (RM200) for Pharmaceutical Chemistry/ Traditional and Complementary Medicine/ Basis of Therapeutics/ Pharmacology. N H Hassan, S M Lim, J Stanslas, S H Lim (2006) Antitumour Activity of SRJ13, a New Semisynthetic Derivative of Andrographolide in Breast Cancer Cell Lines. The 6th MPS Pharmacy Scientific Conference 2006, Crown Princess Hotel Kuala Lumpur, Malaysia

UNIVERSITY LEVEL:

1. Diamond Award. Nur Syakila, Siong Meng Lim, Kalavathy Ramasamy, Fei Tieng Lim and Snezana Agatonovic-Kustrin (2017) CardioLact: Guardian of your gut, protector of your heart. Invention, Innovation and Design Expo 2017, DATC, UiTM Shah Alam.

2. Gold Award. Nur Syakila, Siong Meng Lim, Kalavathy Ramasamy, Fei Tieng Lim and Snezana Agatonovic-Kustrin (2017) CardioLact: Guardian of your gut, protector of your heart. Invention, Innovation and Design Expo 2017, DATC, UiTM Shah Alam.

3. Gold Award. Syamimi Samah, Chin Fen Neoh, Siong Meng Lim, Kalavathy Ramasamy and Yuet Yen Wong. (2017) Diabetes Auxiliary Therapy Programme: A Natural, Holistic Diabetic Care for Type 2 Diabetes Mellitus (T2DM). Invention, Innovation and Design Expo 2017, DATC, UiTM Shah Alam.

4. Diamond Award. N. A. M. Syukri, R. M. Zaki, I. M. Fareez, S. M. Lim and K. Ramasamy (2016) G2BTM: Gut-Brain Revitalized! Invention, Innovation and Design Expo 2016, DATC, UiTM Shah Alam

5. Gold Award. N. A. M. Syukri, R. M. Zaki, I. M. Fareez, S. M. Lim and K. Ramasamy (2016) G2BTM: Gut-Brain Revitalized! Invention, Innovation and Design Expo 2016, DATC, UiTM Shah Alam

6. Diamond Award. Z. M. Zaki, N. N. Ban, K. Ramasamy, C. O. Leong and S. M. Lim (2015) ActiPep: A precious gift from nature. Invention, Innovation and Design Expo 2015, DATC, UiTM Shah Alam

7. Gold Award. Z. M. Zaki, N. N. Ban, K. Ramasamy, C. O. Leong and S. M. Lim (2015) ActiPep: A precious gift from nature. Invention, Innovation and Design Expo 2015, DATC, UiTM Shah Alam

8. Gold Award. N. S. Rahim, S. M. Lim, V. Mani, N. A. Hazalin and K. Ramasamy (2015) VCoil: Guardian of your brain. Invention, Innovation and Design Expo 2015, DATC, UiTM Shah Alam

9. Bronze Award. SMH Dayana, SM Lim, MP Tan, AV Chin, PJH Poi, K Sharul, ABA Majeed, K Ramasamy (2015) ADKin: Make that difference in your life with just a drop of blood. Invention, Innovation and Design Expo 2015, DATC, UiTM Shah Alam

10. Silver medal. R. M. Zaki, Ismail M. Fareez, K. Ramasamy and S. M. Lim (2014) Stay healthy, stay Rho-buzz. Invention, Innovation and Design Expo 2014, DATC, UiTM Shah Alam

11. Bank Islam Malaysia special award. Nor Amalina Ahmad Alwi, Muhamad Fareez Ismail, Kalavathy Ramasamy, Lim Siong Meng, Rakesh Mishra, Vasudevan Mani and Abu Bakar Abdul Majeed (2013) AD-Caps: When gut-brain connects. IIDEX13-SE Innovateur Wannabe!, Dewan Sri Budiman & Anjung Sri Budiman (Annex), UiTM Shah Alam.

12. Category B (Champion). Nor Amalina Ahmad Alwi, Muhamad Fareez Ismail, Kalavathy Ramasamy, Lim Siong Meng, Rakesh Mishra, Vasudevan Mani and Abu Bakar Abdul Majeed (2013) AD-Caps: When gut-brain connects. IIDEX13-SE Innovateur Wannabe!, Dewan Sri Budiman & Anjung Sri Budiman (Annex), UiTM Shah Alam.

13. Consolation Prize. Excellence Laboratory Award 2013. 14. Gold Medal. Mohd Fareez Ismail, Lim Siong Meng,

Kalavathy Ramasamy, Rakesh Mishra, Vasudevan Mani and Abu Bakar Abdul Majeed (2013) Capspro: Thermo- and pH-responsive microspheres with enhanced probiotic stability and targeted delivery in human gut. Invention, Innovation and Design Expo 2013, DATC, UiTM Shah Alam.

15. Second runner up of the St George Clinical School Postgraduate 2012 Three Minute Thesis Competition.

16. Judges’ Choice of the 2011 Faculty of Medicine 3 Minute Thesis Competition and Finalist of the 2011 UNSW Interfaculty 3 Minute Thesis Competition

17. Gold Medal. Ezza Fareesa Binti Mohamad Fakri, Kalavathy Ramasamy and Lim Siong Meng, Aishah Binti Adam and Mizaton Binti Hazizul Hasan (2010) Profermax: Friendly Gut Flora with Therapeutic Enhancement for Human Health. 7th Invention, Innovation and Design, UiTM

18. Gold Medal. Kathleen J. Jalani, Nurul Aqmar Mohamad Nor Hazali, Ibtisam Binti Abdul Wahab, Kalavathy Ramasamy and Lim Siong Meng (2010) NatsynTM: A Potential Anticancer Agent. 7th Invention, Innovation and Design, UiTM

19. Gold Medal (Innovations Category). Lim Siong Meng, Kalavathy Ramasamy, Anthony Cole and Jean Frederick Faizal Weber (2008) ChemofloreTM: Potential New/ Novel Proapoptotic Anticancer Agent. Inventions, Innovations and Design, UiTM

20. Silver Medal (Innovations Category). Kalavathy Ramasamy, Lim Siong Meng, Nor Zaihana Abdul Rahman, Ho Yin Wan, Dr Norhani Abdullah and Sieo Chin Chin (2008) PlantoraTM: A Designer Probiotic for Anticancer Dietary Measures. Inventions, Innovations and Design, UiTM

21. Gold Medal (Innovations Category). Kalavathy Ramasamy, Lim Siong Meng, Jean Frederic Faizal Weber (2007) Kalstevex™: A New, Potential Local Microbial-derived Antineoplastic Agent. Inventions, Innovations and Design, UiTM

22. Silver Medal (Innovations Category). Lua Pei Lin, Wong Tin Wui, Kalavathy Ramasamy, Lim Siong Meng (2007) Flatusorb™: A Solution to Malodorous Flatus. Inventions, Innovations and Design, UiTM

12 INVOLVEMENT IN PROFESSIONAL ORGANISATIONS

• Committee member, Malaysian Association for Cancer Research (PPM-005-10-18102017), 2017-present

• EXCO member, Malaysian Society of Lactic Acid Bacteria (MSLAB), 2017-present

• Committee member, Malaysian Society of Metabolomics (PPM-003-10-29072011), 2016-2018

• Secretary, Malaysian Society of Metabolomics (PPM-003-10-29072011), 2013-2015

• Life Member Chevening Alumni of Malaysia (PPM-001-14-27041998), 2014-Present

13 PARTICIPATION IN CONTINUING EDUCATION

CONFERENCES 1. Main Committee Member/ Co-chair (Scientific Committee),

The International Conference on Drug Discovery and Translational Medicine 2018 (ICDDTM ‘18), MACR, UPM, USM, UiTM, UM, Taylor's University, Quest International University, Mahsa University & Natureceuticals, 3-5 Dec 2018

2. Abstract Reviewer, The 1st International Conference On Pharmacy Practice, Faculty of Pharmacy, UiTM, 27-28 Jun 2018

3. Advisor (Scientific Bureau), The 5th International Postgraduate Conference on Pharmaceutical Sciences (iPoPS 2017), Faculty of Pharmacy, UiTM, 15-18 May 2017

4. Programme Committee, The 4th International Conference on Pharmaceuticals, Nutraceuticals and Cosmetic Science (IPNaCS), Faculty of Pharmacy, UiTM, 12-13 Nov 2015

5. Organizing Committee The 2nd International Conference on Science and Social Research, IRMI, UiTM, 5-6 Oct 2015

6. Co-Chair (Scientific Programme Bureau)/ Abstract Publication, The 3rd International Postgraduate Conference on Pharmaceutical Sciences (iPoPS 2014), Faculty of Pharmacy, UiTM, 11-12 Aug 2014

7. Co-Chair, The 2nd International Postgraduate Conference

Pharmaceutical Sciences (iPoPS 2013), Faculty of Pharmacy, UiTM, 2-7 Sep 2013

8. Committee Member, The National Symposium on Ethics in Clinical and Social Reseach 2017, Faculty of Pharmacy & IRMI, UiTM, 17 Aug 2017

9. Committee Member, The i-Sihat Post Conference Symposium LRGS Project TUA, UKM, UiTM and UPM, 13 Aug 2015

ASSOCIATE SCHOOLS

1. Secretary, IBRO-APRC Associate School of Neuroscience, Faculty of Pharmacy and the Rector’s Office, UiTM, 24-30 Sep 2018

2. Secretary, IBRO-APRC Associate School of Neuroscience, Faculty of Pharmacy, UiTM, 8-14 Aug 2016

WORKSHOPS

1. Organizing Committee, Immuno- labelling & Bio- imaging Workshop, CoRe, IRMI, UiTM, 14-15 Apr 2015

14 COMMUNITY SERVICES

1. Trainer, ILHAM Science Outreach 2017, 5 Jun 2017 2. Speaker/ Exhibitor, Petrosains Science Festival 2014,

KLCC, 15-21 Sep 2014 3. Exhibitor, Petrosains Science Festival 2013, KLCC, 29-30

Jun 2013 4. Scientist, Hotscience, Petrosains, KLCC "Your Brain - Use

it or lose it", 22-27 Oct 2013 5. Project Member/ Organiser, LRGS TUA Health Screening

Programme at the Kampung Tiram Burok Tanjung Karang, 4 May 2016

6. Project Member/ Organiser, LRGS TUA Health Screening Programme at the Taman Berkeley Klang, 26 Apr 2016

7. Project Member/ Organiser, LRGS TUA Health Screening Programme at the Kampung Sungai Terap Kuala Selangor, 22 Jan 2015

8. Project Member/ Organiser, LRGS TUA Health Screening Programme at the Kampung Tiram Burok Tanjung Karang, 21 Jan 2015

9. Supervisor, Research Attachment: Missippi College, USA, Aug 2016

10. Co-supervisor, Research Attachment: Kolej MARA Kuala

Nerang, 28 Nov 2013 11. Facilitator/ Organiser, Science Engagement Program, 17 Oct

2013