Letters to the Editor

modulate components of the immuneresponse, particularly those causing tissuedestruction, are important and should bepursued.

GILLIAN AINSLIEERIC BATEMANRespiratory Clinic,

Groote Schuur Hospital,Observatory,

7925 Cape, South Africa

Variability of inspired oxygen concen-tration with nasal cannulas

The paper by Dr EA Bazuaye and others(August 1992;47:609-1 1) on inspired oxygenconcentrations from nasal cannulas("prongs") is welcome. The potentialhazards of nasal oxygen are under-appreciated, as we found when asking juniormedical staff how they use oxygen duringexacerbations of chronic ventilatory failure.'This inquiry followed a particularly spec-tacular example of "prong poisoning," wherenasal oxygen at 1 litre per minute delivered anFio2 conservatively estimated at 40%.'Nearly half the doctors we asked thoughtnasal oxygen was as good as or better than aVenturi mask in these circumstances, andonly one appreciated that nasal cannulasdeliver an FIo2 which can rise as respiratoryfailure worsens and ventilation falls. Our casesupports the suggestion of Dr Bazuaye andcolleagues that nasal cannulas may be morehazardous during acute exacerbations of ven-tilatory failure, and sustains their statementthat nasal cannulas are "unsatisfactory ifprecise control ofinspired oxygen is desired."

R JO DAVIESJM HOPKIN

Osler Chest Unit,Churchill Hospital,Oxford OX3 7LJ

1 Davies RJO, Hopkin JM. Nasal oxygen inexacerbations of ventilatory failure, anunderappreciated risk. BMJ 1989;299:43-4.

Randomised clinical trial of chestdrainage systems

We should like to comment on the article byDr ANJ Graham and others (June1992;47461-2). The study sample consistedof only postoperative cases, though the auth-ors have extended the recommendation of aPortex drain to trauma and emergencieswhere the risk of tube blockage is higher andlow pressure negative suction is invariablyrequired.' In selecting their sample the auth-ors have excluded patients who would requiresuction, but in the discussion they haveanalysed the requirement of suction in twogroups. This would be a major confoundingfactor in the study. The reasons for reductionin "time to sitting" and in morbidity with aPortex drain, although drainage with bottleswas adequate, are not discussed. As thedrainage systems were not "blind" and therewas variable encouragement for mobilisationby the nursing stafl, there is scope for a bias formobilisation ofthe two study groups and thusin the observations. The major factors in theearly mobility of patients and dischargewould be the type of underlying andassociated illness and complications. Con-

sidering the requirement of suction and thepossibility that Portex tubes can fall out, theauthors' recommendations need furtherevaluation.

R M SARNIAKDepartment of Pulmonary Medicine,

Postgraduate Institute of Medical Educationand Research,

Chandigarh-160 012, India

1 Harriss DR, Graham TR. Management of inter-costal drains. Br J Hosp Med 1991;45:383-6.

AUTHORS' REPLY We thank Dr Samiak forshowing interest in our paper. His assertionthat chest drains inserted after thoracictrauma invariably require suction is not, infact, supported by the reference he cites. Inour experience this is necessary only in casesof persistent pneumothorax, usually becauseof a massive air leak.' Pleural suction is notreadily available at the roadside or battlefieldand the advantages that drainage bags haveover underwater seals in these circumstancesare obvious. This is supported by recentmilitary experience in wartime conditions.2

Patients were not entered into the trial if itwas known that postoperative pleural suctionwould be essential. Randomised patients whosubsequently required suction were retained inthe study and the results were analysedaccording to the intended treatment. This isan accepted method for reducing bias in thistype of clinical trial.3There are inherent difficulties in carrying

out a trial comparing such different methodsof treatment. It was not possible to perform ablind study. Nevertheless, we believe that it isimportant to attempt to assess different tech-niques in a randomised fashion rather thanbasing management on uninformed opinionand speculation. The fact that drainage bagswere found to be safe when used after electivesurgery, which is in effect a form of thoracictrauma, should give clinicians the confidenceto use them, when required, in emergencyconditions.

A N J GRAHAMJA McGUIGAN

Northern Ireland RegionalThoracic Surgical Department,

Royal Victoria Hospital,Belfast BT12 6BA

1 McManus KG, McGuigan JA. Management ofchest injuries. Bailliere's Clinical Anaesth-esiology 1992;6:349-80.

2 Williams JG, Riley TDR, Moody RA. Resus-citation experience in the Falkland Islandscampaign. BMJ 1983;286:775-7.

3 Altman DG. Clinical trials. In: Altman DG, ed.Practical statistics for medical research.London: Chapman and Hall, 1991:440-77.

Barcelona's asthma epidemics

With regard to Dr C Picado's "For Discus-sion" paper (March 1992;47:197-200), wepropose that exogenous 1 5-lipoxygenaseenzyme from soybean modulates the severityof the asthma response in soybean inducedasthma, since soybean is the world's richestknown source of lipoxygenase enzyme and iscausal in epidemic asthma with the unusualclinical features described by Dr Picado.

Plant lipoxygenases are common in natureand could readily be aerosolised during thebulk handling of dry soybean. After antigenchallenge a product of the 15-lipoxygenase

pathway of arachidonic acid metabolism-namely, 15(S)-hydroxy-5,8, 1-cis-13-trans-eicosatetraenoic acid (1 5-HETE)-isobserved in large amounts in bronchoalveolarlavage fluid from patients with chronic stableasthma. Eosinophil suspensions incubatedwith ionophore and granulocytes whenstimulated in the presence of 15-HETEproduce lipoxin A4.' A characteristic ofasthma is the presence of eosinophils inbronchial exudates. Lee et al have foundlipoxin A4 in the bronchoalveolar lavage fluidm human pulmonary disease.2 Lipoxin A4elicits constriction of the guinea pig lungstrip, is chemotactic and chemokinetic inresponse to leucocytes, and may furtherregulate arachidonic acid release. Lai et alshowed that preinhalation of 15-HETEincreased the early asthma response in atopicindividuals by 39%, with no late response,after stimulation by antigen.3 It is thereforelikely that the exacerbation of the asthmaticresponse seen after the inhalation of soybeandust is due to the excessive production oflipoxins or related products. We submit thatthe magnitude of that response is due to theexogenous enzyme. The clinical features inthe Barcelona epidemics that support thishypothesis are: sudden onset, severity, andrapid recovery; augmentation of the earlyasthma response and no late phase response;and a lack of clinical reproducibility withstandard methods of antigen challenge.Dr Picado's paper provides the clinical

observations necessary to describe a novelhuman disease mechanism whereby exogen-ous lipoxygenase enzymes may gain access tohuman substrates and modulate patho-physiological responses.

ANDREW JUDD120 Wilson Crescent,

Saskatoon, Saskatchewan,S7J 2L5

JOHN DOCHERTYDivision of Cardiovascular Sciences,

St Boniface General Hospital Research Centre,University of Manitoba Faculty of Medicine,

351 Tache Avenue,Winnipeg,

Canada R2H 2A6

1 Serhan CN, Samuelsson B. Lipoxins: a newseries of eicosanoids (biosynthesis, stereo-chemistry, and biological activities). Adv ExpMed Biol 1988;229:1-14.

2 Lee TH, Crea AE, Gant, Spur BW. Identifica-tion of lipoxin A4 and its relationship to thesulfidopeptide leukotrienes C4, D4, and E4 inthe bronchoalveolar lavage fluids obtainedfrom patients with selected pulmonary dis-eases. Am Rev Respir Dis 1990;141:1453-8.

3 Lai CKW, Polosa R, Holgate ST. Effect of 15-(S)-hydroxyeicosatetraenoic acid on allergen-induced asthmatic responses. Am Rev RespirDis 1990;141:1423-7.

NOTICE

Latin American conference on cysticfibrosis

The fifth Latin American Cystic FibrosisConference is to take place in Recife, Brazil,on 3-7 April 1993. Further information canbe obtained from Dr Fernando de Abreu eSilva, Rua Duque de Caxias 1327/101, PortoAlegre RS, Brazil 90010 (fax (081) 421.2404).

1086

VOLUME 47: AUTHOR INDEX

AABBOTT J see ROBSON M et alABDALLAH S et al: Opportunistic mycobacteria infection in bronchi-

ectasis (Bx), 251PABE S, SUKOH N, OGURA S, KUNIKANE H, WATANABE N,NAKAJIMA I, TAKEKAWA H, KAWAKAMI Y: Nucleolar organiserregions as a marker of growth rate in squamous cell carcinoma of thelung, 778

A'COURT C, GARRARD C S: Nosocomial pneumonia in the intensivecare unit: mechanisms and significance, 465

ADAM A see JOHNSTON S R D et alADAMSON B B see GALLACHER S J et alADDY D P: Cystic fibrosis: current survival and population estimates to

the year 2000: correspondence, 327AGARWAL P et al: A new device to determine which patients can use a

turbohaler efficiently, 889PAGNEW J E see HASANI A et al

POLOSA R et alAGUSTI A G N see AGUSTI C et al

RODRIGUEZ-ROISIN R et alAGUSTI C, XAUBET A, ROCA J, AGUSTI A G N, RODRIGUEZ-ROISIN R: Interstitial pulmonary fibrosis with and without associatedcollagen vascular disease: results of a two year follow up, 1035

AHMED A H et al: Nasal ventilation v doxapram in the treatment of type

II respiratory failure complicating chronic airflow obstruction, 858PAINSLIE G M, SOLOMON J A, BATEMAN E D: Lymphocyte andlymphocyte subset numbers in blood and in bronchoalveolar lavage andpleural fluid in various forms of human pulmonary tuberculosis at

presentation and during recovery, 513: correspondence, 1085AJAY R see PRABHUDESAI P P et alAKIYAMAY see NISHIMURA M et alAL-BAYARI T H see KURASHI NY et alAL-HAMDAN A see KURASHI NY et alAL-IDRISSI HY see KURASHI NY et alAL-JARAD N, STRICKLAND B, PEARSON M C, RUBENS M B,RUDD R M: High resolution computed tomographic assessment ofasbestosis and cryptogenic fibrosing alveolitis: a comparative study,645

AL-KASSIMI F see AL-MAJED S et alAL-MAJED S, AL-KASSIMI F, ASHOUR M, MEKKI M 0, SADIQ S:Removal of endobronchial mucormycosis lesion through a rigidbronchoscope: short report, 203

ALEXANDER A G et al: Effects of dexamethasone and cyclosporin A on

T lymphocytes in vitro in chronic severe asthma, 873PALI N J et al: Daytime behaviour in 4-5 year old children with mild to

moderate sleep disordered breathing, 220Psee also DAVIES R J 0 et al; MORRISON D et al

ALKNER U see PERSSON C G A et alALLEN M et al: Nebulised bronchodilator therapy in hospital: cost

effectiveness of education, 240PALLISON D J see JOHNSTON S R D et alALONSO A see PLAZA V et alALTINER M see PAKSOY N et alALTON EW FW, ROGERS D F, LOGAN-SINCLAIR R,YACOUB M,BARNES P J, GEDDES D M: Bioelectric properties of cystic fibrosisairways obtained at heart-lung transplantation, 1010

ALTON E W F W et al: 5-nitro-2-(3-phenylpropylamino) benzoic acid(NPPB): a chloride channel "blocker" which alters channel gating,233PAn airway epithelial chloride channel which functions normally in cystic

fibrosis, 868PAMJAD M et al: Right vocal cord palsy at bronchoscopy, 247PANDERSON G: Wegener's granuloma: a series of British cases seen

during 1975-85 by a subcommittee of the British Thoracic Society,217P

ANDERSON H R, POTTIER A C, STRACHAN D P: Asthma frombirth to age 23: incidence and relation to prior and concurrent atopicdisease, 537see also SIBBALD B et al

ANDERSON K et al: Effect of building ventilation on avian antigenconcentration in an animal laboratory, 889POsteoporosis, corticosteroids, and bone disease: comparison of oral and

intravenous bisphosphonates, 854Psee also GALLACHER S J et al

ANDERSON S D, DAVISKAS E: The airway microvasculature andexercise induced asthma: occasional review, 748

ANDERSSON M see PERSSON C G A et alANDO M see HONDA I et alANDREWS J M see BALDWIN D R et alANGUS RM et al: Computed tomography of the lungs in chronic allergic

bronchopulmonary aspergillosis and in asthmatic patients skin testpositive to A. fumigatus, 854PThe bronchodilator and cardiovascular response to high dose infused

atrial natriuretic peptide, 256PAQUILINA R J et al: Breathlessness and shoulder pain, 216P

Respiratory muscle function in patients with severe scoliosis, 848PARAKI S see HONDA I et alARANDA I see ROMERO S et alARAV R see SMOLINSKY A et alARMSTRONG J G see BOWLER S D et alARTVINLI M see PAKSOY N et alASHCROFT T see BOURKE S J et alASHOUR M see AL-MAJED S et alAUCKENTHALER R see PUGIN J et alAYRES J G: Barcelona's asthma epidemics: correspondence, 843

BBACKERV see ULRIK C S et alBAGDADES E K see SQUIRE S B et alBAKKE P see GULSVIK A et alBALDWIN D R, WISE R, ANDREWS J M, HONEYBOURNE D:

Quantitative morphology and water distribution of bronchial biopsysamples, 504

BALKANCI F see COPLU L et alBALTER M S see OH P I and BALTER M SBANG K see STORM H K R et alBANHAM SW see GALLACHER S J et alBARDSLEY P A et al: Effect of breathing strategy on two techniques of

incremental threshold loading, 880PBARI, Y I see COPLU L et al

KALYONCU A F et alBARNES M see BURDON J G W et alBARNES N C: Effects of corticosteroids in acute asthma: editorial, 582

see also POWNEY J et al; SHELDON C D et alBARNES P J: Bradykinin and asthma: occasional review, 979

Poorly perceived asthma: editorial, 408see also ALTON E W F W et al

BARRITT P W: General practitioners and asthma: editorial, 669BARSUM W et al: Adherence of fimbriate (F+) and non-fimbriate (F-)

strains of non-typable Haemophilus influenzae (NTHi) to purifiedhuman tracheobronchial mucin (HTBM) and mucin glycopeptides,252PInteraction of fimbriate (F+) and non-fimbriate (F-) clinical isolates of

non-typable Haemophilus influenzae (NTHi) with human respiratorytract mucus in vitro, 859P

BARTON S E see SMITH D E et alBASTARDO J see GONCALVES J R et alBATEMAN E D see AINSLIE G M et alBATEMAN NT see LEACH R M et al

O'DOHERTY M J et alBATTESTI J-P see PLANES C et alBAUDOUIN S V, BOTT J, WARD A, DEANE C, MOXHAM J: Shortterm effect of oxygen on renal haemodynamics in patients withhypoxaemic chronic obstructive airways disease, 550

BAUDOUIN SV et al: Effect of lipid on pulmonary vasoconstriction in therat, 225P

BAUM G L: A sabbatical year in England: adventitia, 913BAZUAYE E A, STONET N, CORRIS PA, GIBSON G J: Variability of

inspired oxygen concentration with nasal cannulas, 609BEACH J R et al: A survey of airway responsiveness to methacholine and

urinary sodium excretion, 856PBEASLEY R et al: Trial of a "credit card" asthma self management plan in

a Maori community, 890Psee also BREMNER P et al; MONTEFORT S et al; PEARCE N et al

BECK J S see GRANGE J S et alBEL E H see NIEROP G et alBELCHER J R: Charlie's club: adventitia, 737BELL D, LAYTON A: Acute asthma management: audit after feedbackand guidelines, 861P

BELL S C et al: Vitamin A and E concentrations in cystic fibrosis, 867PBELLINGAN G J see WHYTE M K B et alBENFIELD G F A see GANNON P F G et alBENSON D N see EFTHIMIOU J et alBENSON M K see EFTHIMIOU J et al

HARGREAVES M R et alBENTLEY A M et al: Expression of the endothelial and leukocyte

adhesion molecules, ICAM-1, E-selectin andVCAM-l in the bronchialmucosa in steady state asthma and allergen induced asthma, 852PIncreases in activatedT lymphocytes, eosinophils, and cytokine mRNA

expression for IL-5 and GM-CSF in bronchial biopsies after allergen

1 089Thorax 1992;47:1089-1103

Author Index

inhalation challenge in atopic asthmatic patients, 852PBENTLEY S see SPENCE D P S et alBEREND N see PETERS M J et alBERGER H A see NYGAARD S D et alBERGLUND E: Shunting through a patent foramen ovale: correspondence,

575BERRY L, BRAUDE S, HOGAN J: Refractory hypoxaemia afterpneumonectomy: diagnosis by transoesophageal echocardiography:short report, 60

BEYNEN J H see VLASVELD L Th et alBIAGI G see HAID M M et alBIERNACKI H, DOUGLAS N J: Evaluation of a computerised

polysomnography system, 234PBIRCHALL M A et al: Histamine challenge in allergic rhinitis: effect of

single doses of an anticholinergic agent and a adrenoceptor agonist,231P

BISCAIA I see GONQALVES J R et alBLACK C M see WELLS A U et alBLAIR A L T see NAMNYAK S S et alBLOODWORTH J, TOMASHEFSKI J F: Localised pulmonary meta-

static calcification associated with pulmonary artery obstruction, 174BLOWER G see LOCK S H et alBODANI H et al: Comparison of the mini-Wright and the Wright pocketpeak flow meters, 230P

BOLLIGER CT, FOURIE P R, KOTZE D, JOUBERT J R: Relation ofmeasures of asthma severity and response to treatment to outcome inacute severe asthma, 943

BONE M F: Use of nebulised azlocillin to prevent the emergence ofresistant pseudomonas in long term treatment with ciprofloxacillin,251PKUBIK M M: Comparison of the Bricanyl Turbohaler with the

pressurised meter dose inhaler (MDI) in adult asthmatics, 238PKUBIK M M: Comparison of a simple benchtop assay (Acculevel) for

plasma theophylline estimation with HPLC, 255PNAGENDRAN V: Use of nebulised immunoglobulin as adjunctive

therapy for severe pulmonary infection in bronchiectasis, 894PBOOK NOTICESBARNES P J, editor: British Medical Bulletin: a series of expert

reviews---asthma, 1992, 764BORDWO R A, MOSER K M, editors: Manual of clinical problems inpulmonary medicine, 3rd edition, 1991, 1081

BRAY M A, ANDERSON W H, editors: Mediators of pulmonaryinflammation, 1991, 764

BREWIS R A L: Lecture notes on respiratory disease, 4th ed. 1991,139

CLARKTJ H, GODFREY S, LEET H: Asthma, 3rd ed. 1991, 576COOVADIA J M, BENATAR S R: A century of tuberculosis--South

African perspectives, 1991, 460CROFTON J, HORNE N, MILLER F: Clinical tuberculosis, 1992,668

EVERINGHAM R, WOODWARD S, editors: Tobacco litigation-AFCO zv TIA.The case against passive smoking, 1991, 400

HOWARD P: Respiratory medicine in clinical practice, 1991, 67KALINER M A, BARNES P J, PERSSON C G A: Asthma-its

pathology and treatment, 1991, 67LEVY M, HILTON S: Asthma in practice, 1992, 1081LYNCH J P, DeREMEE R A editors: Immunologically mediatedpulmonary diseases, 1991, 67

MITCHELL D M: Recent advances in respiratory medicine 5, 1991,460

MOXHAM J, editor: Assisted ventilation, 1991, 326PROUST A J, editor: History of tuberculosis in Australia, New Zealandand Papua New Guinea, 1991, 576

RUDNIK J, KURZAWA R: Atlas of rare chest diseases in children,1991, 139

SMITH R, editor: The health of the nation:The BMJ view, 1991, 844TOBIN M J: Respiratory monitoring, 1992, 992WALDHAUSEN J A, ORRINGER M B editors: Complications in

cardiothoracic surgery, 1990, 138WIDDICOMBE J, DAVIES A: Respiratory physiology, 2nd ed, 1991,

326BOOTS R J, ROBERTS A W, McEVOY D: Immune thrombocytopenia

complicating pulmonary tuberculosis: case report and investigation ofmechanisms, 396

BOSJ A H see SCHMEKEL B et alBOSLEY C M et al: Patient compliance with inhaled medication: doescombining beta-agonists with corticosteroids improve compliance?845P

BOTHAMLEY G H, RUDD R, FESTENSTEIN F, IVANYIJ: Clinicalvalue of the measurement of Mycobacterium tuberculosis specific antibodyin pulmonary tuberculosis, 270

BOTT J see BAUDOUIN S V et alBOURKE SJ, QUINN A G, FARR P M, ASHCROFTT, GIBSON G J:

Neutrophilic alveolitis in Sweet's syndrome: short report, 572BOURKE S J et al: Chlamydia pneumoniae serology in UK populations,218PVentilation perfusion scans in cryptogenic fibrosing alveolitis, 881P

BOWLER S D, MITCHELL C A, ARMSTRONG J G: Corticosteroids inacute severe asthma: effectiveness of low doses, 584

BOYLE I T see GALLACHER S J et alBRADDING P et al: Cytokine immunoreactivity in the normal human

nasal mucosa, 896PInterleukin-4 immunoreactivity is localised to mast cells in the upper

respiratory tract, 231PBRADSHAW J R see KORMAS P et alBRAID G M et al: Survey of domiciliary nasal continuous positive airway

pressure in obstructive sleep apnoea, 878PBRAMBILLA C see PEPIN J L et alBRAND P L P, QUANJER P H, POSTMA D S, KERSTJENS H A M,KOETER G H, DEKHUIJZEN P N R, SLUITER H J, DUTCHCHRONIC NON-SPECIFIC LUNG DISEASE (CNSLD) STUDYGROUP: Interpretation of bronchodilator response in patients withobstructive airways disease, 429

BRANTHWAITE M A see ELLIOTT MW et alBRAUD M L see PFITZENMEYER P et alBRAUDE S see BERRY L et alBRAUNER M see PLANES C et alBRAY D H et al: Antiretroviral treatment modifies phenotype of alveolarmacrophages in AIDS patients, 223P

BREACH N M see EDEN C G et alBREDIN C P et al: Calculated annual risk of tuberculosis infection in

south west Ireland 1983-90, 228PBREEDERBELD N see WEMPE J B et alBREMNER P, BURGESS C D, CRANE J, McHAFFIE D, GALLETLY

D, PEARCE N, WOODMAN K, BEASLEY R: Cardiovascular effectsof fenoterol under conditions of hypoxaemia, 814

BREMNER P R et al: Inhaled formoterol: a comparison of thecardiovascular and metabolic effects with salbutamol and fenoterol,882P

BRESLIN A B X see PETERS M J et alBRIDGEMAN M M E et al: Comparison of the effects of oxidants on

liposomes and on alveolar epithelial cells, 246PBRITISH THORACIC SOCIETY: Summer meeting, University of

Sheffield, 8-10 July 1992, proceedings, 845Winter meeting, London, 9-1 1 December 1991, abstracts, 209

BRITISH THORACIC SOCIETY RESEARCH COMMITTEE:Clinical course of empyema, 851PThe microbiology of pleural empyema, 850PThe treatment of empyema, 851P

BRITlTON J: Pollution and respiratory morbidity: how much do weaccept? 391: correspondence repty, 762

BRITTON J R see ELBORN S et alBROPHY C see MIER A et alBROWN D M, DONALDSON K: Macrophage aggregates in rats

exposed to dust from the air of wool mills: mechanism of formation,213P

BROWN E M see DILWORTH J P et alBROWN G M, MACNEE W: A novel, rapid technique for isolating

peripheral blood neutrophils in the rat: in vitro function and in vivomigration in the lungs, 243P

BROWN P H et al: Peak inspiratory flow rates in acute asthma: are theyadequate for efficient use of a Turbohaler? 239PSerum IgG antibodies to Pseudontonas cepacia (PsC) in adults with cystic

fibrosis (CF), 252PSystemic effects of high dose inhaled steroids: a comparison of

beclomethasone dipropionate (BDP) and budesonide (BUD), 845PBRUCE I et al: Prevalence of respiratory symptoms and self reported

asthma in a student population, 209PBRUDIN L H, RHODES C G, VALIND S 0, BUCKINGHAM P D,JONES T, HUGHESJ M B: Regional structure-function correlations inchronic obstructive lung disease measured with positron emissiontomography, 914

BRUM G see GONCALVES J R et alBRYDEN F M see GALLACHER S J et alBUCKINGHAM P D see BRUDIN L H et alBUCKNALL C E et al: Improving hospital asthma management--where

next? 845PWhy uncritical criterion based audit is not enough: analysis of PEFR

data from a prospective asthma audit, 884PBURDON J G W, BARNES M, HARRIS A: Treatment of pulmonary

aspergilloma with itraconazole: correspondence, 328BURGE P S: Peak flow measurement: editorial, 903

see also GANNON P F G et alBURGE S see KONGERUD J et alBURGESS C see PEARCE N et alBURGESS C D see BREMNER P et alBURGESS C et al:The cardiovascular effects of isoprenaline are increasedunder conditions of combined hypoxaemia and hypercapnia in healthymales, 856P-

BURNETT D: Defensins: ancient but potentially dangerous weapons inthe armoury, 195Fine tuning of cell behaviour by modulation of plasma membrane

receptors, 563BURNEY P et al: Effect of a low sodium diet on asthma in general

1 090

Author Index

practice, 256PBURNSTOCK G see RENNICK R E et alBUSH A: Pulmonary function in chronic renal failure: effects of dialysis

and transplantation: correspondence, 763BUTLER J et al: Lung injury and cardiopulmonary bypass: a pilot study

of infused pentoxifylline in a model of ARDS, 244PBUTT AY et al: Effects of intravenous prostacyclin on haemodynamicsand pulmonary gas exchange in severe chronic obstructive pulmonarydisease, 893P

CCADRANEL J see DE LASSENCE A et alCALDERON M et al: Infiltration by lymphocytes in the nasal mucousmembrane in allergic rhinitis, 232P

CALVERLEY P M A: Domiciliary ventilation in chronic obstructive lungdisease: editorial, 334HOWATSON R, FLENLEY D C, LAMB D: Clinicopathological

correlations in cor pulmonale, 494see also NISAR M et al

CAMBRIDGE G see LEAKER B et alCAMERON I R see LEACH R M et alCAMPBELL I A: Four weeks' versus three months' anticoagulation for

deep vein thrombosis and/or pulmonary embolism, 217PCAMPBELL I A et al: Nicotine patches v placebo in 234 hospital patients,886Psee also HUSSAIN S F et al

CAMUS P see PFITZENMEYER P et alCAPELASTEGUI A see SOBRADILLO V et alCAPELL H A see MARSHALL D A S et alCAPEWELL S see MORRISON D et alCAQUET R see SITBON 0 et alCAREY FA,WALLACEWA H, FERGUSSON RJ, KERR K M, LAMBD: Alveolar atypical hyperplasia in association with primary pulmonaryadenocarcinoma: a clinicopathological study of 10 cases, 1041

CARPIAUX J-P see NOSEDA A et alCARRERES A see FIZ J A et alCARROLL M P see ELLIOTT MW et alCASALE R, NATALI G, COLANTONIO D, PASQUALETTI P:

Circadian rhythm of peak expiratory flow in children passively exposedand not exposed to cigarette smoke, 801

CASALS F see PLAZA V et alCASHMAN B see HUSSAIN S F et alCATTELL S A et al: Recruitment difficulties in a clinical trial for a newasthma drug, 254P

CHANG D-B seeYANG P-C et alCHARAN N B see CONNOLLY M J et alCHARLTON I: Controlled study evaluating a nurse run asthma clinic in

a paediatric department, 221PCHATHAM K et al: Use of the FlutterVRP 1 device in post-thoracotomy

patients, 236PCHAUHAN A J: Improvement in six minute walking test after regular

balloon inflation in patients with severe airflow limitation, 211PCHEN K see POZNIAK A L et alCHERRIE B see CULLEN RT et alCHETCUTI P, PHELAN P D, GREENWOOD R: Lung function

abnormalities in repaired oesophageal atresia and tracheo-oesophagealfistula, 1030

CHILVERS E R et al: Presence of multiple phosphoinositidase C isoformsin bovine tracheal smooth muscle (BTSM), 213Psee alsoWHYTE M K B et al

CHINN S, RONA R J: Height and age adjustment for cross sectionalstudies of lung function in children aged 6-11 years, 707Height and age adjustment of lung function in children, 236Psee also LEACH R M et al

CHONANT see MIURA C et alCHOWIENCZYK P J et al: Dependence of resistance during interruptionon rate of change of flow before interruption, 862P

CHRISTIE P E et al: Effects of lipoxin A4 (LXA4) on airway responses inasthmatic subjects, 242P

CHU J see PETERS M J et alCIMOLAI N, ROGERS P, SEEAR M: Corynebacterium pseudodiph-

theriticum pneumonitis in a leukaemic child: short report, 838CI'RON K: Tuberculin positive children: editorial, 768CLARK C J: Asthma and exercise: a suitable case for rehabilitation:

editorial, 765CLARKE SW see HASANI A et al

POLOSA R et alCLOSE P R et al: Comparison of two protocols for incremental exercise

testing, 210PCOAKLEY J F see JISHI F et alCOCK H see SHELDON C D et alCOLANTONIO D see CASALE R et alCOLE P, MATAR K S: Pleural abrasion: a new method of pleurodesis:

correspondence, 575COLES S J see EFTHIMIOU J et alCOLLARD Ph, WEYNANTS P, FRANCIS Ch, RODENSTEIN D 0:Treatment of relapse of small cell lung cancer in selected patients with

the initial combination chemotherapy carboplatin, etoposide, andepirubicin, 369

COLLINS J V see SULLIVAN PJ et alCOLQUHOUN I W et al: Steroid therapy and airway complications

following pulmonary transplantation, 248PValue of donor lung lavage in identification of postoperative infection

following lung transplantation, 248PCOLVILLE A, BAKER M: Culture positive pulmonary mycobacterial

disease in Nottingham 1979-91: an increasing proportion of non-tuberculous infection, 875P

CONGLETON J, MUERS M F: Bronchial carcinoma, airflow obstruc-tion, and breathlessness, 862P

CONGLETON J et al: Basal metabolic rate, weight loss, and decline inFEV, in chronic obstructive pulmonary disease (COPD), 847P

CONNETT G J, LENNEY W: Breathing better but blue: oxygensaturation changes after nebulised salbutamol in acute asthma, 220P

CONNOLLY C K et al: At what step do general practitioners referpatients with asthma and other chronic diseases? 239PFive year review of asthma: mortality, 209P

CONNOLLY M J, CROWLEY J J, CHARAN N B, NIELSON C P,VESTAL R E: Reduced subjective awareness of bronchoconstrictionprovoked by methacholine in elderly asthmatic and normal subjects asmeasured on a simple awareness scale, 410

CONWAY S P, SIMMONDS E J, LITTLEWOOD J M: Acute severedeterioration in cystic fibrosis associated with influenza A virusinfection, 112

COOK D G et al: Passive smoke exposure in children, 861PRelation of passive smoking assessed by salivary cotinine and ques-

tionnaire on spirometry in children, 850PTime trends in respiratory symptoms in childhood over a 24 year

period, 853PCOOKSON A G I see COOKSON J B and COOKSON A G ICOOKSON J B, COOKSON A G I: Does a positive Heaf test reaction in

Asian schoolchildren predict later breakdown of tuberculosis?, 776COOPER B G et al: Lipid and carbohydrate metabolism in subjects with

obstructive sleep apnoea (OSA) and the effects of CPAP, 235PCOOPER C B et al: New method for determining oxygen uptake kinetics:

application to chronic obstructive pulmonary disease (COPD) patients,210P

COOPER S M et al: Audit of inhaler technique in patients and hospitalstaff, 237P

COPLU L, EMRI S, SELCUK Z T, KALYONCU F, BALKANCI F,;AHIN A A, BARI,Y I: Life threatening chylous pleural and pericardialeffusion in a patient with Behcet's syndrome: short report, 64see also KALYONCU A F et al

COREY J see NAMNYAK S S et alCORRAL J see SOBRADILLO V et alCORREIA M J S see GONCALVES J R et alCORRIN B see GEDDES D M and CORRIN B

WELLS A U et alCORRIS P A see BAZUAYE E A et alCORZO J E, DE LEON F L, GOMEZ-MATEOS J, LOPEZ-CORTESL,VAZQUEZ R, GARCIA-BRAGADO F: Pneumothorax secondary toseptic pulmonary emboli in tricuspid endocarditis: short report, 1080

COSGROVE A P see GRAHAM A N J et alCOSIO M G see LEBY R D et alCOSTABLE U: BOOP and COP: correspondence, 207COSTELOE K L see MURCH S H et alCOTTRILL C P see MILLER R F et alCOUDERT B see PFITZENMEYER P et alCOULOMB M see PEPIN J L et alCOWAN R A see GALLACHER S J et alCOWEN M E see DONNELLY R J et alCOX A L seeVAN KLAVEREN R J et alCRANE J et al: Partial v full beta-receptor agonism: a clinical study of

inhaled salbutamol and fenoterol, 882Psee also BREMNER P et al; PEARCE N et al

CRANK P see KALRA S et alCRAWLEY D E et al: Changes in reactivity in pulmonary arteries of ratsexposed to hypoxia for seven days, 226P

CREMONA G et al: Hypoxic pulmonary vasoconstriction of isolatedporcine lungs is not dependent on changes in endogenous nitric oxiderelease, 893P

CRISP A J et al: Comparison of the radiographic features of pulmonaryinfections with Mycobacterium kansasii and Mycobacterium tuberculosis,876P

CROFTON J: Confessional: adventitia, 1062CROWLEY J J see CONNOLLY M J et alCULLEN R T, CHERRIE B, SOUTAR C A: Immune responses tocolophony, an agent causing occupational asthma, 1050

CULLEN R T et al: In vitro toxic effect of colophony to lung epithelialcells contrasts with its lack of effect on the lung in vivo, 214P

CUNDALL D B see TEALE C et alCUNDELL D R et al: Factors from non-typable Haemophilus influenzae

inhibiting neutrophil locomotion in vitro: gel filtration and HPLCanalysis, 868P

CUNNANE G et al: Is a three drug regimen the best treatment for

1091

Author Index

tuberculosis? 224PCURRIE D see SULLIVAN P J et alCURULLV see MORELL F et al

DDA COSTA P see DAVISON A M et alDA COSTA PEREIRA A et al: Selfmanagement of asthma-like symptoms

in a Scottish community, 890PDAMANI P see PARARAJASINGAM C D et alDANTON M see RITCHIE A J et alDAVIDSON A C see LEACH R M et alDAVIES P D B: My only private patient: adventitia, 650DAVIES P D 0: Recent developments in the management of thepulmonary complications of HIV disease: correspondence, 1084

DAVIES P D 0 et al: Pseudo-outbreak of tuberculosis in a paediatriconcology ward, 220PRisk of tuberculosis infection in residential homes for the elderly,228P

The standardised notification ratio for tuberculosis: a simple way ofassessing service needs, 875P

DAVIES R J 0

ALI N J, STRADLING J R: Neck circumference and other clinicalfeatures in the diagnosis of the obstructive sleep apnoea syndrome,101

HOPKIN J M: Variability of inspired oxygen concentration with nasalcannulas: correspondence, 1086

DAVIES R J 0 et al: Controlled trial of nasal CPAP in heart failure withsleep disordered breathing, 216PNight time blood pressure in obstructive sleep apnoea, snoring, and

normal sleep, 216PDAVIES S see SMITH D E et alDAVISKAS E see ANDERSON S D and DAVISKAS EDAVISON A M, LOWE J W, DA COSTA P: Adenocarcinoma arising in

a mucinous cystadenoma of the lung: short report, 129DE BRUIN P F et al: Respiratory and quadriceps muscle strength in

chronic adult onset asthma, 216PThe effects of dopaminergic stimulation on airway dynamics

and respiratory muscle strength in Parkinson's disease, 880PUltrasonographic evaluation and strength assessment of the respiratoryand thigh muscles in patients with chronic asthma, 849P

DE GRACIA J see MORELL F et alDE IONGH R, ING A, RUTLAND J: Mucociliary function, ciliary

ultrastructure, and ciliary orientation in Young's syndrome, 184DE LASSENCE A, LECOSSIER D, PIERRE C, CADRANEL J,STERN M, HANCE A J: Detection of mycobacterial DNA in pleuralfluid from patients with tuberculous pleurisy by means of the poly-merase chain reaction: comparison of two protocols, 265

DE LEON F L see CORZO J E et alDE SOUZA A C et al: Surgical treatment of empyema thoracis: analysis of88 cases between 1987 and 1991, 851P

DE VUYST P see LEDUC D et alDEANE C see BAUDOUIN S V et alDEKHUIJZEN P N R see BRAND P L P et alDEKKER F W, SCHRIER A C, STERK P J, DIJKMAN J H: Validity ofpeak expiratory flow measurement in assessing reversibility of airflowobstruction, 162

DELASPRE 0 see PUGIN J et alDELEMARRE J F M see VLASVELD LTh et alDEMIRCAN A see PAKSOY N et alDEMIRYUREK A T et al: Investigation of the mechanism of hypoxia

induced pulmonary vasoconstriction in human isolated pulmonaryarteries, 225P

DENBURG J A see PIN I et alDENNIS C et al: Heart-lung transplantation for end stage respiratory

disease in cystic fibrosis, 248PDEROM E Y, PAUWELS R A: Time course of bronchodilating effect of

inhaled formoterol, a potent and long acting sympathomimetic, 30DEV D et al: Analysis of amylase isoenzyme in the differential diagnosis of

amylase rich pleural effusions, 887PDEVALIA J L et al: Effect of nitrogen dioxide (NO2) on synthesis oftumour necrosis factor-a (TNF-a) by human bronchial epithelial cells invitro, 245P

DI BISCEGLIE M see HAID M M et alDICKINSON S A see MILLER M R et alDIJKMAN J H see DEKKER FW et al

NIEROP G et alSCHREUR H JW et al

DILWORTH J P, WHITE R J, BROWN E M: Microbial flora of thetrachea during intubation of patients undergoing upper abdominalsurgery, 818

DILWORTH J P et al: Salbutamol does not influence the incidence ofchest infection after upper abdominal surgery in high risk patients,249P

DIRKSEN A, MADSEN F, ENGEL T, FR0LUND L, HEINIG J H,MOSBECH H: Airway calibre as a confounder in interpreting bronchialresponsiveness in asthma, 702see also ULRIK C S et al

DOBSON M B: Use of jet mixing devices with an oxygen concentrator,1060

DOCHERTY J see JUDD A and DOCHERTY JDODD M see ROBSON M et alDODD M E et al: Costs of a district nebuliser compressor service,863P

DOIG J C et al: Pulmonary pressures and resistances in non-suppurativelung disease and their influence on survival following single lungtransplantation, 247P

DOLOVICH J see PIN I et alDONALD J J see MILLER R F et alDONALDSON K et al: Long fibres of amosite asbestos stimulate rat

alveolar macrophage secretion of tumour necrosis factor and the effectis enhanced by opsonisation with immunoglobulin G, 214P

DONNELLY M R see NAMNYAK S S et alDONNELLY R JPAGE R D: Endoscopic assisted microthoracotomy, 850PPAGE R D, COWEN M E: Endoscopy assisted microthoracotomy:

initial experience, 490see also HIND C R K and DONNELLY R J

DONNELLY S C, HASLETT C: Cellular mechanisms of acute lunginjury: implications for future treatment in the adult respiratory distresssyndrome: editorial, 260: correspondence reply, 668

DONNELLY S et al: Endotoxin, antiendotoxin core bodies, and oxygenrequirement after multiple trauma, 245PNeutrophil elastase levels and oxygen requirement after multiple

trauma, 245PDORCA J see MANRESA F et alDOUGLAS J G see PACKE G E et al

WALSHE A D P et alDOUGLAS N J see KERR K M et alDRAKE S see SHAHMANESH M et alDROST E see SELBY C et alDRUMMOND G B: Body composition and exercise performance in

patients with chronic obstructive pulmonary disease (COPD): corres-pondence, 66

DRUMMOND N A et al: Integrated care for asthma: the view fromgeneral practice, 238P

DRYDEN C M et al: A three probe portable system for assessment ofpulmonary endothelial permeability, 893P

DRYSDALE P see PITHIE A D et alDU BOIS R M: How T cells recognise antigen: implications for lung

diseases, 127see also LEAKER B et al; MILBURN H J et al; WELLS A U et al

DU PELOUX MENAGE H, DUFFY S, YATES D W, HUGHES J A:Reversible sensor motor impairment following prolonged ventilationwith isoflurane and vecuronium for acute severe asthma: short report,1078

DUFFY S see DU PELOUX MENAGE H et alDUIVERMAN E J see MERKUS P J F M et alDUJIC Z, ETEROVIC D,TOCILJ J: Pulmonary function in chronic renal

failure: effects of dialysis and transplantation: correspondence, 763DUROUX P see SITBON 0 et alDUTCH CHRONIC NON-SPECIFIC LUNG DISEASE (CNSLD)STUDY GROUP see BRAND P L P et al

EEARIS J: Lung sounds: editorial, 671EARIS J E see NISAR M et alEBDEN P et al: Measurement of magnetic particles in the lung bypneumomagnetometry, 888P

EDEN C G, BREACH N M, GOLDSTRAW P: Treatment of desmoidtumours in Gardner's syndrome: short report, 662

EDGE J: Bungalow hospital and coral reef: adventitia, 376EFFROS R: Bronchoalveolar lavage as a research tool: correspondence,207

EFTHIMIOU J, MOUNSEY P J, BENSON D N, MADGWICK R,COLES S J, BENSON M K: Effect of carbohydrate rich versus fat richloads on gas exchange and walking performance in patients with chronicobstructive lung disease, 451

ELBORN S, SHALE D J, BRITTON J R: Cystic fibrosis: current survivaland population estimates to the year 2000: correspondence reply, 327

ELBORN S et al: Comparison of intravenous ceftazidine and aztreonam inthe treatment of respiratory exacerbations in cystic fibrosis, 867PTumour necrosis factor-a, resting energy expenditure and cachexia in

cystic fibrosis, 868PELLIOTT M W, SIMONDS A K, CARROLL M P, WEDZICHA J A,BRANTHWAITE M A: Domiciliary nocturnal nasal intermittentpositive pressure ventilation in hypercapnic respiratory failure due tochronic obstructive lung disease: effects on sleep and quality of life,342

ELLIOTT MW et al: Double blind, placebo controlled study of the acuteeffects of fluoxetine on sleep and breathing in asymptomatic patientswith obesity, 235PThe role of expiratory positive airway pressure (EPAP) during nasal

ventilation, 858PELLIS C J see PITHIE A D et al

1 092

Author Index

EMERY C, TENG G Q: Vascular effects of chronic treatment of bothnormoxic and chronically hypoxic rats with L-NAME, an inhibitor ofnitric oxide release, 891P

EMRI S see COPLU L et alKALYONCU A F et al

ENGELT see DIRKSEN A et alENGLAND A et al: Measurement of urinary cyclic gmp in patients with

obstructive sleep apnoea, 878PEPSTEIN R S see JUNIPER E F et alERAUT D et al: British Thoracic Society (BTS) survey of respiratory

function laboratories and technicians, 848PERJEFALT I see PERSSON C G A et alERSOZ A, SONCUL H, GOKGOZ L, KALAYCIOGLU S,TUNAOGLU S, KAPTANOOLU M,YENER A: Horseshoe lung withleft lung hypoplasia: short report, 205

ESPERSEN F see PEDERSEN S S et alETEROVIC D see DUJIC Z et alEVANS A E et al: Respirable fraction and clinical response in relation to

orifice size of aerosol inhalers, 239PEVANS A J et al: Comparison of the radiographic features of pulmonary

infections with Mycobacterium malmoense and Mycobacterium tuberculosis,875P

EVANS D H see SPENCE D P S et alEVANS J see SHAHMANESH M et alEVANS M R see HUSSAIN S F et alEVANS S A, HOPKINSON N D, KINNEAR W J M, WATSON L,POWELL R J, JOHNSTON I D A: Respiratory disease in systemiclupus erythematosus: correlation with results of laboratory tests andhistological appearance of muscle biopsy specimens, 957

EVANS S A et al: Bronchial hyperresponsiveness, airway calibre and atrialnatriuretic peptide in chronic heart failure, 881PComparison of the clinical features of pulmonary infections withMycobacterium kansasii and Mycobacterium tuberculosis, 876P

Diaphragmatic strength in chronic heart failure, 216PNormal range for transdiaphragmatic sniff pressure with cathetermounted pressure transducers, 881P

EVANS T W: The pulmonary physician and critical care: introduction,463

FFARR P M see BOURKE S J et alFAUX J A, SHALE D J, LANE D J: Precipitins and specific IgG antibody

to Aspergillus fumigatus in a chest unit population, 48FAZEL S B, HOWIE S E M, KRAJEWSKI A S, LAMB D: B lymphocyte

accumulations in human pulmonary sarcoidosis, 964FENECK R 0 see POWNEY J et alFENNER J A K see GALLACHER S J et alFERGUSSON R J see CAREY F A et alFERINI-STRAMBI L see ZUCCONI M et alFERNANDES A see GONCALVES J R et alFERNANDEZ M C see MARTINEZ-LOPEZ M A et alFERRETTI G see PEPIN J L et alFERRIE P J see JUNIPER E F et alFESTEN J see VAN KLAVEREN R J et alFESTENSTEIN F see BOTHAMLEY G H et alFICK R B see NYGAARD S D et alFIFE K et al: Could lung cancer management be affected by age related

treatment policies? 251PFIROOZAN S see GRAY H H and FIROOZAN SFISHWICK D, PICKERING C A C: Byssinosis-a form of occupational

asthma: editorial, 401FISHWICK D et al: Comparison of six minute walk test performancebetween patients with cystic fibrosis and emphysema, 862P

FISHWICK K A et al: Evaluation of the "Ventilometer": a hand heldspirometer, 229P

FITTING J-W: Nutritional support in chronic obstructive lung disease:editorial, 141

FIZ J A, CARRERES A, ROSELL A, MONTSERRAT J M, RUIZ J,MORERA J M: Measurement of maximal expiratory pressure: effect ofholding the lips, 961

FLEMING J see MITCHELL D M et alFLENLEY D C see CALVERLEY P M A et al

JEFFREY A A et alFOLEY N M et al: Atypical Pneumocystis carinii pneumonia, 857P

Tuberculosis and AIDS: is the "white plague" up and coming? 223PFORBES A see SMITH D E et alFORSEN L et al: Interaction between current smoking, leanness, and

physical inactivity in the prediction of hip fracture, 861PFOSTER R W, JUBBER A 5: Bronchodilator effectiveness of inhaledMKS 492 assessed in normal human subjects, 242P

FOUCHER P see PFITZENMEYER P et alFOUNTAIN S W: Pleural abrasion: a new method of pleurodesis:

correspondence reply, 575FOURIE P R see BOLLIGER C T et alFOX G A, McCORMACK D G: A new look at the pulmonary circulation

in acute lung injury, 743FOX W, MITCHISON D A: Tuberculosis in the third world: correspon-

dence, 327FRANCIS Ch see COLLARD Ph et alFRASER F see JISHI F et alFRENCH N et al: Induced sputum as a diagnostic tool in community

acquired pneumonia, 874PFRETTE C, WEI S M, NEUKIRCH F, SESBOUE R, MARTIN J-P,JACOB M-P, KAUFFMANN F: Relation of serum elastin peptideconcentration to age, FEV,, smoking habits, alcohol consumption, andprotease inhibitor phenotype: an epidemiological study in working men,937

FREW A J et al: Bronchial reactivity, smoking, atopy, and accelerateddecline in FEV,, 221PSpecificity of plicatic acid induced histamine release from broncho-

alveolar lavage cells and bronchial biopsy tissue in asthma due towestern red cedar, 214P

FREY J G see TSCHOPP J M et alFRIEND J A R see VAN TEIJIUNGEN E and FRIEND J A RFRIMODT-M0LLER N see STORM H K R et alFRITH P A et al: Interrelations among physiological and psychological

function in chronic airflow limitation (CAL) patients, 850PFR0LUND L see DIRKSEN A et alFUJIMURA M, SAKAMOTO S, KAMIO Y, MATSUDA T: Effects of

methacholine induced bronchoconstriction and procaterol inducedbronchodilation on cough receptor sensitivity to inhaled capsaicin andtartaric acid, 441

FUTATSUKA M see HONDA I et al

GGABEZ P see PFITZENMEYER P et alGALLACHER S JFENNER J A K, ANDERSON K, ADAMSON B B, BANHAM S W,BOYLE I T: Vertebral fractures in steroid dependent asthma andinvolutional osteoporosis: a comparative study: correspondence, 207

FENNER J A K, ANDERSON K, BRYDEN F M, BANHAM S W,LOGUE F C, COWAN R A, BOYLE I T: Intravenous pamidronatein the treatment of osteoporosis associated with corticosteroiddependent lung disease: an open pilot study, 932

GALLETLY D see BREMNER P et alGANDEVIA S C see GORMAN R B et alGANNON P F G, BURGE P S,VENFIELD G FA: Occupational asthmadue to polyethylene shrink wrapping (paper wrapper's asthma): shortreport, 759

GANNON P F G et al: Different methods for calculating diurnal variationin peak expiratory flow, 882PEffect of the number of peak expiratory flow readings a day on diurnal

variation, 845PRespiratory symptom, spirometry, and employment status follow up in

occupational asthma, 229PNon-linearity of the Mini-Wright peak expiratory flow meter and its

effect on calculation of diurnal variation, 891PGANTV et al: Alveolar macrophage accessory cell function correlates with

bronchoalveolar lavage lymphocytosis in asthma, 873PGARCIA-BRAGADO F see CORZO J E et alGARDEN G M F, AYRES J G: Psychosocial factors in brittle asthma,209P

GARDINER P V et al: Repeatability of cell counts in bronchoalveolarlavage (BAL) fluid in asthmatic subjects, 241P

GARRARD C S see A'COURT C and GARRARD C SGASCOIGNE A D, CORRIS P A: Prevalence of al antitrypsin deficiency(aAT) in patients with emphysema referred for lung transplantation atFreeman Hospital, 248P

GASCOIGNE A D et al: Value of plasma soluble IL2-r monitoring in lungtransplantation, 249PVentilation-perfusion relationships after single lung transplantation foremphysema, 248P

GASTON J S H see PITHIE A D et alGAZZARD B G see SMITH D E et alGEDDES D M: Inhaled corticosteroids: benefits and risks: editorial,404CORRIN B: BOOP and COP: correspondence reply, 207see also ALTON EW FW et al

GELDER CM et al: Restriction of peripheralT cell receptorV-a gene usedin atopy and atopic asthma, 853P

GENEVOIS P A see LEDUC D et alGEORGE PJ M, HADLEY J M, MANTELL B S, RUDD R M: Medium

dose rate endobronchial radiotherapy with caesium-1 37: new techniques,474see also POWNEY J et al

GIBBONS J R P see GRAHAM A NTJ et atRITCHIE A J et al

GIBBONS L see LEBY R D et alGIBBS A R: Wegener's granuloma: histological features, 217PGIBSON G J see BAZUAYE E A et al

BOURKE S J et alGIBSON P G see PIN I et alGIJZELW P see NIEROP G et alGILL S S, NKERE U U, WALESBY R K: An expansible cannula: a new

1093

Author Index

technique for chest drain insertion, 657GILLOOLY M see McLEAN A et al

WALLACEW A H et alGINANNI R see MICHEL 0 et alGIRGIS-GABARDO A see PIN I et alGODDARD M see WESTON M and GODDARD PGODDEN D J: Outcome of wheeze in childhood: airway function 25

years later, 221Psee also WALSHE A D P et al

GOKGOZ L see ERSOZ A et alGOLDMAN J M et al: Extrathoracic tuberculosis, presentation and

outcome: Leeds TB survey 1991, 877PThe effect of endobronchial radiotherapy on tumour morphology and

lung function, 250PTuberculosis diagnosed in a contact clinic: Leeds TB survey 1991,876P

Tuberculosis in the elderly: presentation and outcome: Leeds tuber-culosis survey 1991, 223P

Who treats tuberculosis and how effectively: Leeds tuberculosis survey

1991, 222PGOLDSTRAW P: Endoscopy assisted microthoracotomy: editorial, 489The practice of cardiothoracic surgeons in the perioperative staging of

non-small cell lung cancer: editorial, 1

see also EDEN C G et al; PETERS P et al; WELLS A U et alGOMEZ-MATEOS J see CORZO i E et alGOMM S A et al: Differential effect of inhaled prostacyclin on airway

calibre in hyper-responsive subjects, 872PGONCALVESJ R, BRUM G, FERNANDES A, BISCAIA I, CORREIAMJ S, BASTARDO J: Aeromonas hydrophila fulminant pneumonia in a

fit young man: short report, 482GONZALEZJ J see MARTINEZ-LOPEZ M A et alGOOR D A see SMOLINSKY A et alGORMAN R B, McKENZIE D K, GANDEVIA S C, PLASSMAN B L:

Inspiratory muscle strength and endurance during hyperinflation andhistamine induced bronchoconstriction, 922

GOTTI G see HAID M M et alGRAHAM A et al: Inhibition of amiloride sensitive transport by

5-hydroxytryptamine in sheep and human airway epithelia, 233PTrial of nebulised amiloride in patients with cystic fibrosis, 867P

GRAHAM A NJ, COSGROVE A P, GIBBONSJ R P, McGUIGAN J A:Randomised clinical trial of chest drainage systems, 461: correspondence,1086

GRANGEJ M, STANFORDJ L, BECKJ S: Lymphocyte andlymphocyte subset numbers in blood and bronchoalveolar lavage andpleural fluid in various forms of human pulmonary tuberculosis:correspondence, 1085

GRANGE K L et al: Effect of amiloride on the airway response to

metabisulphite in asthma, 872PGRAY H H, FIROOZANS: Management of pulmonary embolism, 825GREALLY Pet al: Tumour necrosis factor-a, leukotrienes, and airflow

obstruction in cystic fibrosis, 868PGREENJ H, ALLEN M B: Basal metabolic rate in sleep apnoea, 878PGREEN M see MIER A et alGREENOUGH A see YUKSEL B and GREENOUGH AGREENWOOD R see CHETCUTI P etal

GREIFF L see PERSSON C G A et alGRIFFITHS MJ D see MESSENT M and GRIFFITHS MJ DGRIFFITHS P D see SQUIRE S B et alGRIS P see LEDUC D etal

GRUNDYJ E see SQUIRE S B et alGRZYBOWSKI 5: Tuberculosis in the third world: correspondence reply,

327GUERREIRO D et al: Experimental bronchiectasis producing potential of

bacteria frequently isolated from purulent sputum of patients withbronchiectasis (Bx), 859P

GUGGER M, VOCK P: Effect of reduced expiratory pressure on

pharyngeal size during nasal positive airway pressure in patients withsleep apnoea: evaluation by continuous computed tomography, 809

GULSVIKA, BAKKE P, HUMERFELT 5, OMENAAS E,TOSTESONT, WEISS S T, SPEIZER F E: Single breath transfer factor for carbon

monoxide in an asymptomatic population of never smokers, 167GURR C E et al: Effects of intranasal challenge with interleukin-8,893P

GUYATT G, KELLER J, SINGER J, HALCROW 5, NEWHOUSE M:Controlled trial of respiratory muscle training in chronic airflowlimitation, 598

GUYATT G H see JUNIPER E F et a!

HHADLEY J M see GEORGE P J M et a!HAID M M, PALADINI P, MACCHERINI M, DI BISCEGLIE M,BIAGI G, GOTTI G: Air transport and the fate of pneumothorax inpleural adhesions: short report, 833

HAITJEMA Tj, VAN VELZEN-BLAD H,VAN- DEN BOSCH J M M:Extrinsic allergic alveolitis caused by goose feathers in a-duvet: shortreport, 990

HALCROW S see GUYATT G et al

HALL I P et al: Control of beta adrenoceptor desensitisation in culturedhuman airway smooth muscle (HASM) cells, 212P

HALL J R et al: A comparison of the cost effectiveness of salmeterol vsalbutamol in patients with moderate asthma, 883P

HALPIN D M G et al: The effects of acute and chronic hypoxia on thesecretion of vasopressin, renin, and aldosterone, 846P

HAMBLIN A S et al: Patients with sarcoidosis express increasedconcentrations of leucam adhesion proteins (CD 11/CD 18) on theirperipheral blood leucocytes, 894P

HANCE A J see DE LASSENCE A et alHANRATH P see HURTER T and HANRATH PHANSELL D M see WELLS A U et alHARDMAN A E see SINGH S J et alHARGREAVE F E see PIN I et alHARGREAVES M R, MOWAT AG, BENSON M K: Acute pneumonitis

associated with low dose methotrexate treatment for rheumatoidarthritis: report of five cases and review of published reports, 628

HARRIS A see BURDONJ G W et alHARRIS M K et al: Pulmonary sequelae of chlorine gassing, 236PHARRISON N K see SHEPPARD M N and HARRISON N K

WELLS A U et alHARRISON T S et al: A criterion based audit of community acquiredpneumonia, 874P

HARTLEYJ P R et al: Bronchodilator effect of oxitropium bromidecompared with ipratropium bromide, 865P

HASANI A, SPITERI M A, PAVIA D, LOPEZ-VIDRIERO M T,AGNEWJ E, CLARKE SW: Effect of temazepam on tracheobronchialmucus clearance, 298see also POLOSA R et al

HASEGAWA S seeYAMASHITAY et alHASLETT C see DONNELLY S C and HASLETT CHASSAN W U et al: Bronchial reactivity and airways obstruction in

rheumatoid arthritis, 854PHATTON M et al: Comparison of "abruptly stopping" with "tailing off'

prednisolone in acute asthma, 229PHATTON M Q F et al: Bone mineral density changes in women taking

inhaled corticosteroids, 228PComparison of the use of peak flow meters before and after1 October

1990 in new patients referred from general practice with obstructiveairways disease, 237P

HAYCOCKJ see NISAR M et alHAYWARD S A et al: A nurse run asthma clinic: assessment of patient self

treatment for asthma, 238PHEARD B E: Prescribed fenoterol and death from asthma in New

Zealand, 1981-7: a further case-control study: correspondence, 400HEARD B E et al: Apposition of fibroblasts to mast cells and lymphocytes

in normal human lung and in cryptogenic fibrosing alveolitis: ultra-structure and cell perimeter measurements, 219P

HEATH D: A journey to Sakti: adventitia, 963HEGARTY V etal: Differences in adherence of Branhamella catarrhalis

organisms in the presence and absence of respiratory tract infection,252P

HEGESHJ see SMOLINSKY A etal

HEIMER D see LIEBERMAN D and HEIMER DHEINIGJ H see DIRKSEN A et alHENDERSON B L see WHYTE M K B etal

HENDERSONJ C etal: Caffeine decreases histamine induced broncho-constriction in mild asthma, 889P

HEPWORTHJ see KALRA S et a!HERAS M see ROCAJ et a!HEYSTRATEN F M J see VAN KLAVEREN R J et a!HIDA W see MIURA C et a!HIGGINS S P et a!: Tine testing HIV positive patients, 877PHILL A L et a!: Effect of addition of exercise to chest physiotherapy on

sputum expectoration and lung function in adults with cystic fibrosis,867P

HILLER T K see JUNIPER E F et a!HILVERING C see VAN BIEZEN P et a!HIND C R K, DONNELLY R J: Expandable metal stents for tracheal

obstruction: permanent or temporary? A cautionary tale, 757HITCHINGS DJ

see MILLER M R et a!HODSON M E see TAYLOR R F H et a!HOGAN F et a!: Effect of nedocromil sodium on leucocyte migration innormal and asthmatic leucocytes, 243P

HOGAN F P et a!: Eicosanoid production by leucocytes in airways

disease, 242PHOGAN J see BERRY L et alHOIBY N see JOHANSEN H K and HOIBY N

PEDE RSE NS S Pt a!HOLGATE ST see JOHNSTON S L et a!

MONTEFORT S et alPARARAJASINGAM C D et a!POLOSA R et a!

HONDA I, KOHROGI H, ANDO M, ARAKI 5, UENO T, FUTAT-SUKA M, UEDA A: Occupational asthma induced by the fungicidetetrachloroisophthalonitrile: short report, 760

HONEYBOURNE D see BALDWIN D R et a!

1 094

Author Index

HOPKINJ M see DAVIES RJ 0 and HOPKINJ MHOPKINSON N D see EVANS S A et alHORTON A see SHAHMANESH M et alHOSKER H S R et al: Assessment of patients for home nebulisers: survey

of present practice in Yorkshire, 863PChemiluminescence responses of alveolar macrophages obtained from

each lung in patients with lung cancer, 250PProvision of home nebulisers in Yorkshire, 863P

HOUSTON S see POZNIAK A L et alHOWATSON R see CALVERLEY P M A et alHOWIE S E M see FAZEL S B et alHUGH-JONES P: A rewarding combination: adventitia, 729HUGHES D F see NAMNYAK S S et alHUGHESJ A see DU PELOUX MENAGE H et alHUGHESJ M B see BRUDIN L H et al

WHYTE M K B et alHUMERFELT S see GULSVIK A et alHUMPHRIES M:The management of tuberculous meningitis: editorial,

577HURTER T, HANRATH P: Endobronchial sonography: feasibility and

preliminary results: new techniques, 565HUSSAIN S F, WATURA R, CASHMAN B, CAMPBELL I A, EVANSM R: Tuberculosis contact tracing: are the British Thoracic Societyguidelines still appropriate: short report, 894

HUSSAIN S F et al: Attitudes to smoking and smoking habit among ahospital staff: a five year follow up,850PAudit of a standard tuberculosis contact procedure, 227P

HUTCHISONJ T see MUSHTAQ M et al

IBRAHIM E M see KURASHI NY et alILES P B see PITHIE A D et alILYAS M et al: Platelet activating factor (PAF) and non-specific bronchial

hyperresponsiveness, 255PIND P W see JOHNSTON S R D et al

SPRING J et alING A see DE IONGH R et alINKSTER G et al: Audit of maintenance asthma treatment before

admission to hospital with acute severe asthma, 884PINNES J A see PITHIE A D et alIREDALE M J et al: Induced sputum: a method of assessment of airway

inflammation in asthma, 212PISHAQUI N A et al: The frequency content of snores in humans, 879PISKENDARANI A see KALYONCU A F et alISOSHIMA K see MORI M et alIVANYI J see BOTHAMLEY G H et al

JJACK C I A et al: Circulating free radical activity in patients with

cryptogenic fibrosing alveolitis, 219PComparison of induced sputum cytology with bronchial biopsy in the

diagnosis of lung cancer, 251PSerum concentrations of free radical activity in patients with BCNU

related pulmonary fibrosis, 219PSimultaneous tracheal and oesophageal pH (stop) measurements in

patients with gastrooesophageal reflux and asthma: microaspirationdoes occur, 881P

JACKSON J E see WHYTE M K B et alJACKSON M, SHNEERSON J M: The East Anglian GP domiciliary

oxygen treatment survey, 864PJACKSON M et al: Use of 24 hour ambulatory oximetry to monitor the

response to assisted ventilation with NIPPV, 215PJACKSON R see PEARCE N et alJACOB M-P see FRETTE C et alJAESCHKE R see JUNIPER E F et alJANSSEN J P see WESTERM ANN C J J and JANSSEN J PJAVAHERI S, SICILIAN L: Lung function, breathing pattern, and gas

exhange in interstitial lung disease, 93JEFFREY A AWARREN P M: Should we judge a mask by its cover?, 543WARREN P M, FLENLEY D C: Acute hypercapnic respiratory failure

in patients with chronic obstructive lung disease: risk factors and useof guidelines for management, 34

JENNEY M E M et al: Exercise capacity in survivors of childhood Wilms'stumour, 220P

JEYASINGHAM K see KORMAS P et alJISHI F, SISSONS C E, SILVERSTONE E J, COAKLEY J F, FRASER

F: Oesophageal dissection after thrombolytic treatment for myocardialinfarction: short report, 835

JOHANSEN B et al: Static lung volumes in healthy subjects assessed byhelium dilution during occlusion of one mainstem bronchus, 848P

JOHANSEN H K, H0IBY N: Seasonal onset of initial colonisation andchronic infection with Pseudomonas aeruginosa in patients with cysticfibrosis in Denmark, 109

JOHNSON A 0 C: Short term variability of saturation in patients beingassessed for long term oxygen treatment, 864P

JOHNSON M A see SQUIRE S B et al

JOHNSON M E, LLOYD H C: Salmeterol xinafoate: a comparison withnedocromil sodium in patients with mild asthma, 883P

JOHNSTON I D A see EVANS S A et alJOHNSTON S et al: Local hyperthermia reduces nasal blockage and

vascular leakage after allergen challenge in seasonal rhinitic subjects,232PWeb 2086, a platelet activating factor antagonist, has no steroid sparing

effect in asthmatic patients requiring inhaled corticosteroids, 871PJOHNSTON S L, PERRY D, O'TOOLE S, SUMMERS Q A, HOL-GATE S T: Attenuation of exercise induced asthma by local hyper-thermia, 592

JOHNSTON S R see SPRING J et alJOHNSTON S R D, ADAM A, ALLISON D J, SMITH P, IND P W:

Recurrent respiratory obstruction from a mediastinal bronchogeniccyst: short report, 660

JOHNSTONE D J see SULLIVAN PJ et alJONES D J M et al: Nasal intermittent positive pressure ventilation:

assessment and comparison of volume and pressure preset ventilatorsystems in chronic respiratory failure, 859P

JONES G S see SHAHMANESH M et alJONES K P et al: Do interleukin-6, IgG or CD23 provide evidence for B

cell activation in extrinsic allergic alveolitis? 214PSerum cytokines and salivary platelet aggregation factor in acute severe

asthma, acute myocardial infarction, and stable asthma, 870PTargetting asthma care in general practice, 238P

JONES N L see SIMPSON K et alJONES PW, BAVEYSTOCK C M: Sleep disturbance due to respiratory

symptoms: a marker of generalised impairment of health and wellbeing,855P

JONES T see BRUDIN L H et alJONES Y see NISAR M et alJORDANOGLOU J: A new and simple technique for estimating alveolar

carbon dioxide tension during tidal breathing, 210PJORIS F see TSCHOPP J M et alJOUBERTJ R see BOLLIGER CT et alJUBBER A S, FOSTER R W: Relationship of the slope of the log dose-

response curve to sensitivity to methacholine and starting airway calibrein normal human subjects, 242P

JUBBER A S et al: Dose-response relation of nebulized salbutamol againstbronchoconstriction induced by methacholine, 873P

JUDD A, DOCHERTY J: Barcelona's asthma epidemics: correspondence,1086

JUNIPER E F, GUYATT G H, EPSTEIN R S, FERRIE PJ, JAESCHKER, HILLERT K: Evaluation of impairment of health related quality oflife in asthma: development of a questionnaire for use in clinical trials,76

KKAELIN R M see TSCHOPP J M et alKALAYCIOGLU S see ERSOZ A et alKALLIS P et al: Intravascular oxygen supplementation, 215PKALRA S, CRANK P, HEPWORTH J, PICKERING C A C, WOOD-COCK A A: Absence of seasonal variation in concentrations of thehouse dust mite allergen Der pl in South Manchester homes, 928

KALRA S et al: Der pl levels six months after treatment of houses withliquid nitrogen, 219Psee also PANDIT A et al

KALYONCU A F, SELCUK ZT, ISKENDARANI A, COPLU L, EMRIS, SAHIN A A, BARIS Y I: Alternative and complementary medicinefor asthma: correspondence, 762

KALYONCU F see COPLU L et alKAMIO Y see FUJIMURA M et alKANEMURA T see NAGAI A et alKANTHAKUMAR K et al: Pseudomonas aeruginosa pyocyanin slowshuman ciliary beating via a cyclic amp dependent mechanism, 869PPyocyanin from Pseudomonas aeruginosa perturbs respiratory epitheliumby intracellular redox cycling, 252P

KAO N L, MOY J N, RICHMOND G W: Achilles tendon rupture: anunderrated complication of corticosteroid treatment: correspondence,484

KAPLAN D K: Mediastinal lymph node metastases in lung cancer: is sizea valid criterion: editorial, 332

KAPTANOGLU M see ERSOZ A et alKARUNAKARAN L S G et al: Effects of steroid on macrophagelymphocyte interactions in sarcoidosis, 215P

KAUFFMANN F see FRETTE C et alKAWAKAMIY see ABE S et al

NISHIMURA M et alKAWANA A et at: Multinucleated cells in bronchoalveolar lavage fromAIDS patients, 240P

KELLER J see GUYAT G et alKEMENY J-L see PLANES C et alKEMP A S see PETERS M J et alKENDRICK A H: Gas mixtures for estimated CO transfer factor, 862PSMITH E C: Asthma policy in schools in Great Britain, 237P

KENDRICKA H et al: Investigation of micro-organisms in wedge-bellowsspirometer tubes, 862P

1 095

Author Index

KEOGH B F see SWAMI A and KEOGH B FKERR K M, LAMB D,WATHEN C G,WALKERW S, DOUGLAS N J:

Pathological assessment of mediastinal lymph nodes in lung cancer:implications for non-invasive mediastinal staging, 337: correspondence,842see also CAREY F A et al; WALSHE A D P et al

KERREBIJN K F see MERKUS P J F M et alKERSTJENS H A M see BRAND P L P et alKHAN A R, see SCHMEKEL B et alKHAN J et al: Drug resistance of Mycobacteriuni tuberculosis in Karachi,

Pakistan, 227PKIDNEY J C et al: Effect of an oral potassium channel activator,BRL38227, in asthmatics: comparison with oral salbutamol, 254P

KIDOGAWA H see MORI M et alKIKUCHI Y see MIURA C et alKILBURN K H, WARSHAW R J, THORNTON J C, THORNTON K,MILLER A: Predictive equations for total lung capacity and residualvolume calculated from radiographs in a random sample of theMichigan population, 519

KILLIAN K see SIMPSON K et alKING K see SHELDON C D et alKINNEARW et al: Can nocturnal hypoxaemia be predicted from daytime

respiratory function tests in patients with a thoracoplasty? 879PIs hvypercapnia related to diaphragm fatigue in patients with a

thoracoplasty? 880PKINNEARW J M see EVANS S A et alKINSELLA D et al: Can multivariate analysis reduce the number of

intermediate V:Q scans? 236PKISHI F see NISHIMURA M et alKLEINKNECHT D see PLANES C et alKOCH C see PEDERSEN S S et alKOETER G H see BRAND P L P et al

WEMPE J B et alKOHROGI H see HONDA I et alKOLENDOWICZ R see PIN I et alKONGERUD J, S0YSETH V, BURGE S: Serial measurements of peak

expiratory flow and responsiveness to methacholine in the diagnosis ofaluminium potroom asthma, 292

KONNO K see NAGAI A et alKORMAS P, BRADSHAW J R, JEYASINGHAM K: Preoperativecomputed tomography of the brain in non-small cell bronchogeniccarcinoma, 106

KORT E seeWEMPE J B et alKOTZE D see BOLLIGER C T et alKRAJEWSKI A S see FAZEL S B et alKRASNIK M see STORM H K R et alKRISHNAN K et al: Difference in systemic absorption produced by

inhaling corticosteroid by different devices, 891PKUITERT L M: Beta agonists in asthma--state of the art: report on a

Royal Society of Medicine seminar, 568KUMAR S, LAWFORD P: Acute asthma: can admission rates be

reduced? 239PKUMAR S et al: Yield from tuberculosis contact tracing: Birmingham

1987-9, 875PKUMARARATNE D S see PITHIE A D et alKUNII 0 seeYAMAGUCHI M et alKUNIKANE H see ABE S et alKUO S-H seeYANG P-C et alKURASHI N Y, AL-HAMDAN A, IBRAHIM E M, AL-IDRISSI H Y,AL-BAYARI T H: Community acquired acute bacterial and atypicalpneumonia in Saudi Arabia, 115

LLACHMANN B, see SCHMEKEL B et alLACQUET L K see VAN KLAVEREN R J et alLACROIX S see PFITZENMEYER P et alLAI C K see POLOSA R et alLAMB D see CALVERLEY P M A et al

CAREY F A et alFAZEL S B et alKERR K M et alMcLEAN A et alWALLACEW A H et al

LAMBERT E J, PETERS S A, ROLLES C J: Cystic fibrosis: currentsurvival and population estimates to the year 2000: correspondence, 400

LANE D J: Alternative and complementary medicine for asthma:correspondence, 762see also FAUX J A et al

LANES S F, POOLE C, WALKER A M: Prescribed fenoterol and deathfrom asthma in New Zealand, 1981-7: a further case control study:correspondence, 574

LANGDON C G,THOMPSON J: Fluticasone propionate: a comparisonwith budesonide in adult asthmatic patients, 891P

LATIF A S see POZNIAK A L et alLAU K-Y: Endobronchial actinomycosis mimicking pulmonary neo-

plasm: short report, 664LAZAROWICZ H et al: Cross refractoriness between sodium meta-

bisulphite and exercise induced asthma, 873PLEACH R M: Right ventricular hypertrophy in chronically hypoxic rats is

associated with increased IGF-1 gene expression, 858PDAVIDSON A C, CHINN S, TWORT C H C, CAMERON I R,BATEMAN NT: Portable liquid oxygen and exercise ability in severerespiratory disability, 781

TREACHER D F: Oxygen transport: the relation between oxygendelivery and consumption, 971

LEACH R M et al: Endothelium dependent acute hypoxic vasoconstric-tion in isolated pulmonary arteries, 226PVasorelaxant effect of lemakalim on pulmonary arteries of normoxic and

chronically hypoxic rats, 227PLEAKER B, CAMBRIDGE G, DU BOIS R M, NEILD G H: Idiopathicpulmonary haemosiderosis: a form of microscopic polyarteritis: shortreport, 988

LECOSSIER D see DE LASSENCE A et alLEDUC D, GRIS P, LHEUREUX P, GEVENOIS P A, DE VUYST P,YERNAULT J C: Acute and long term respiratory damage followinginhalation of ammonia: short report, 755

LEEY-C seeYANG P-C et alLEIGH T R et al: A qualitative and quantitative comparison of the

polymerase chain reaction and immunofluorescence for diagnosingPneumocystis carinii pneumonia in AIDS patients, 857PDNA amplification by the polymerase chain reaction to detect

Pneumocystis carinii colonisation in asymptomatic human immuno-deficiency virus (HIV) infected subjects, 223P

LEITCH A G: An audit of prolixity, investigation rates and follow up ratesin 490 new consultations in a chest clinic, 881PExtrapulmonary tuberculosis in Lothian, 1980-1989: delay from start

of symptoms to diagnosis, 877PLETOVANEC N see TSCHOPP J M et alLEVY P A see PEPIN J L et alLEVY R D, COSIO M G, GIBBONS L, MACKLEM PT, MARTINJ G:

Induction of sleep apnoea with negative pressure ventilation in patientswith chronic obstructive lung disease, 612

LHEUREUX P see LEDUC D et alLI X et al: The evaluation of airway distensibility in asthma, 849PLI X Y et al: Development of an in vitro model of epithelial cell

permeability: effect of cigarette smoke condensate, 245PStudies of airspace epithelial permeability in acute lung inflammation

using a rat model, 244PLIEBERMAN D, HEIMER D: Effect of dietary sodium on the severity of

bronchial asthma, 360LIPMAN M C I see SQUIRE S B et alLIPWORTH B J et al: Sex differences in hypokalaemic, chronotropic, and

electrocardiographic effects of inhaled terbutaline, 882Psee also RAHMAN A R A et al

LITTLEWOOD J M see CONWAY S P et alLIU S F et al: Differential responses of guinea pig pulmonary arteries to

neuropeptides and neural stimulation, 226PLLEWELLYN-JONES C, STOCKLEY R A: Effects of elastase inhibitorson extracellular proteolysis by neutrophils, 246P

LLOBERES P, MONTSERRAT E, MONTSERRAT J M, PICADO C:Sputum sol phase proteins and elastase activity in patients with clinicallystable bronchiectasis, 88

LOCK S H, BLOWER G, PRYNNE M, WEDZICHA J A: Comparisonof liquid and gaseous oxygen for domiciliary portable use, 98

LOESCH A see RENNICK R E et alLOGAN-SINCLAIR R see ALTON E W FW et alLOGUE F C see GALLACHER S J et alLOPEZ-CORTES L see CORZO J E et alLOPEZ-VIDRIERO MT see HASANI A et alLOUGHREY C et al: Tuberculosis among health service employees,224P

LOWE JW see DAVISON A M et alLOZEWICZ S et al: Allergen induced release of inflammatory mediators

into nasal lavage fluid and the effect of topical glucocorticoids, 231PLUENGO M, PICADO C Vertebral fractures in steroid dependentasthma and involutional osteoporosis: a comparative study: correspond-ence reply, 207

LUH K-T see YANG P-C et alLUSKY A see SMOLINSKY A et alLYONS E et al: Evaluation of the FlutterVRP I device in young adults with

cystic fibrosis, 237P

MMABILLE J-P see PFITZENMEYER P et alMcCARTHY P T et al: New HPLC method for the measurement ofplasma terbutaline in patients with brittle asthma treated by continuousinfusion, 884P

McCARTNEY N see SIMPSON K et alMcCARTY M see MITCHELL D M et alMACCHERINI M see HAID M M et alMcCORMACK D G see FOX G A and McCORMACK D GMcDEVITT D G see RAHMAN A R A et alMcDONALD A F see PACKE G E et alMacDONALD T T see MURCH S H et al

1096

Author Index

McELHINNEY P see NAMNYAK S S et alMcEVOY D see BOOTS RJ et alMACFARLANEJ T see VENKATESAN P and MACFARLANEJ TMcGUIGAN J A see GRAHAM A NJ et alMcGUIGAN S see SIBBALD B et alMcHAFFIE D see BREMNER P et alMACKAY I S see TAYLOR R F H et alMACKAY TW et al: Atrial natriuretic peptide (ANP) release in the sleep

apnoea hypopnoea syndrome, 235PRole of the non-adrenergic, non-cholinergic nervous system (NANC) in

the overnight variation of airway calibre in asthma, 243PMcKEAN M E see WALSHE A D P et alMcKENZIE D K see GORMAN R B et alMACKLEM PT see LEBY R D et alMcLEAN A, WARREN P M, GILLOOLY M, MacNEE W, LAMB D:

Microscopic and macroscopic measurements of emphysema: relation tocarbon monoxide gas transfer, 144

MACNAUGHTON P D et al: Initial experience of artificial surfactanttherapy in adult acute lung injury, 243P

MACNEE B see SELBY C et alMacNEEW see McLEAN A et alMADAN I et al: Pre-employment chest x ray films for health service staff:who needs them? 877P

MADDEN B et al: Medium term results of heart and lung transplantation,247P

MADGWICK R see EFTHIMIOU J et alMADSEN F see DIRKSEN A et alMAGRINA J see ROCA J et alMAHASHUR A A see PRABHUDESAI P P et alMANN J S see MUSHTAQ M et alMANO K seeYAMAGUCHI M et alMANRESA F, DORCA J, PRATS E: Fatal lung abscess due to

LactobaciUlus casei ss rhamnosus: correspondence, 992MANTELL B S see GEORGE P J M et alMARSH P et al: Atopy as a risk factor for cryptogenic fibrosing alveolitis,849P

MARSHALL D A S, STURROCK R D, PORTER D, CAPELL H A:Pneumocystis carinii pneumonia complicating low dose methotrexatetreatment for rheumatoid arthritis: correspondence, 67

MARTI S see ORIOL A et alMARTIN B see STANFORD C F et alMARTIN C see ROMERO S et alMARTIN J G see LEBY R D et alMARTIN J-P see FRETTE C et alMARTIN T et al: Complications following multiple transbronchial lung

biopsy, 886PMARTINEZ-LOPEZ M A, PENA J M, QUIRALTE J, FERNANDEZM C, GONZALEZ J J, PATRON M, VAZQUEZ J J: Bronchocentricgranulomatosis associated with pure red cell aplasia and lymphadenop-athy: short report, 131

MATAR K S see COLE P and MATAR K SMATHUR R, JOHNSTON I D A: Optimum time of surgical intervention

for persistent air leak in spontaneous pneumothorax, 222PMATSUDA T see FUJIMURA M et alMATTHEWS A W: A survey of malignant mesothelioma in Portsmouth

1982-91, 851PMATUSIEWICZ S et al: Pet ownership and associated morbidity in

asthmatic patients, 210PMATUSIEWICZ S P et al: Subclinical Pneumocystis carinii detected at

routine bronchoscopy in a proportion of patients with small cell lungcancer, 857P

MAXWELL D L et al: Nedocromil sodium inhibits histamine releasewithin proximal asthmatic airways in vivo, 212P

MAYNARD R L,WALLER RE: Air pollution and respiratory morbidity:correspondence, 762

MEDICAL RESEARCH COUNCIL CARDIOTHORACIC EPIDE-MIOLOGY GROUP: National survey of notifications of tuberculosis inEngland and Wales in 1988, 770

MEERAN K: Bone turnover during short course prednisolone treatment

in patients with chronic obstructive airways disease: correspondence,1084

MEKKI M 0 see AL-MAJED S et alMENAGE H du PELOUX, DUFFY S, YATES D W, HUGHES J A:

Reversible sensorimotor impairment following prolonged ventilationwith isoflurane and vecuronium for acute severe asthma: short report

1078MERKUS PJ FM, ROODA H M E,VAN ESSEN-ZANDVLIET E E M,DUIVERMAN EJ, QUANJER Ph H, KERREBIJN K F: Assessment ofbronchodilatation after spontaneous recovery from a histamine chal-lenge in asthmatic children, 355

MESSENT M, GRIFFITHS M J D: Pharmacotherapy in lung injury,651

MICHAELIDES S et al: Effect of ipratropium bromide on posture

induced changes of expiratory flow indices in asthmatic and normal

subjects, 253PMICHEL 0, GINANNI R, SERGYSELS R: Relation between the

bronchial obstructive response to inhaled lipopolysaccharide and

bronchial responsiveness to histamine, 288MIER A, BROPHY C, MOXHAM J, GREEN M: Repetitive stimulation

of phrenic nerves in myasthenia gravis, 640MIKI H see MIURA C et alMILBURN H J, PRENTICE H G, DU BOIS R M: Can lung functionmeasurements be used to predict which patients will be at risk ofdeveloping interstitial pneumonitis after bone marrow transplantation?421

MILES J F, MILLER M R: Influence of peak flow meter non-linearity onrecorded PEF variability, 891P

MILES J F et al: Changes in Mini-Wright peak flow meter performanceafter prolonged use, 890P

MILLER A see KILBURN K H et alMILLER M R, DICKINSON S A, HITCHINGS D J:The accuracy of

portable peak flow meters, 904MILLER R et al: Investigation of acute respiratory illness in HIV positive

patients using indium labelled polyclonal immunoglobulin scans,240P

MILLER R FMITCHELL D M: Pneumocystis carinii pneumonia, 305TOMLINSON M C, COTTRILL C P, DONALDJ J, SPITTLE M F,SEMPLE S J G: Bronchopulmonary Kaposi's sarcoma in patientswith AIDS, 721

see also MITCHELL D M and MILLER R FMILLER R F et al: Lung function abnormalities in patients withpulmonary Kaposi's sarcoma, 888P

MITCHELL C A see BOWLER S D et alMITCHELL D MMcCARTY M, FLEMING J, MOSS F M: Bronchopulmonary

Kaposi's sarcoma in patients with AIDS, 726MILLER R F: Recent developments in the management of thepulmonary complications of HIV disease, 381

see also MILLER R F and MITCHELL D M; WALKER D A et alMITCHISON D A see FOX W and MITCHISON D AMITSUI Y seeYAMASHITA Y et alMIURA C, HIDAW, MIKI H, KIKUCHIY, CHONANT,TAKISHIMAT: Effects of posture on flow-volume curves during normocapnia andhypercapnia in patients with obstructive sleep apnoea, 524

MIYAMOTO K see NISHIMURA M et alMIYASHITA H seeYAMAGUCHI M et alMOAT N E et al: Porcine cardiopulmonary bypass: a model of acute lung

injury with increased pulmonary endothelial permeability, 244PMOGHISSI K: The practice of cardiothoracic surgeons in the perioper-

ative staging of non-small cell lung cancer: correspondence, 327MOGHISSI K et al: Endoscopic photodynamic therapy (PDT) for

malignant endobronchial obstruction, 251PMONTEFORT S, ROBERTS J A, BEASLEY R, HOLGATE S T,ROCHE W R: The site of disruption of the bronchial epithelium inasthmatic and non-asthmatic subjects, 499

MONTEFORT S et al: Circulating adhesion molecules in asthmatic andnon-asthmatic subjects, 852PThe expression of leucocyte endothelial adhesion molecules is increased

in perennial allergic rhinitis, 232PMONTSERRAT E see LLOBERES P et alMONTSERRAT J M see FIZ J A et al

LLOBERES P et alMORCOS S K et al: Bronchography complementing fibreoptic broncho-

scopy to evaluate the solitary pulmonary nodule, 886PMORELL F, ORRIOLS R, DE GRACIA J, CURULL V, PUJOL A:

Controlled trial of intravenous corticosteroids in severe acute asthma,588

MORENO J see ORIOL A et alMORERA J M see FIZ J A et alMORGAN A see SULLIVAN P J et alMORGAN DW see TAYLOR R F H et alMORGAN M D L: Detection and quantification of pulmonary emphy-sema by computed tomography: a window of opportunity: editorial,1001see also SINGH S J et al; SPENCE D P S et al

MORGANW K C: Every dogma has its day: adventitia, 808MORI M, KIDOGAWA H, ISOSHIMA K: Thoracic duct cyst in the

mediastinum: short report, 325MORRELL N W et al: Collateral ventilation and gas exchange in thenormal lung, 21 1P

MORRISON D, ALI N J, ROUTLEDGE P A, CAPEWELL S: Boneturnover during short course prednisolone treatment in patients withchronic obstructive airways disease, 418: correspondence, 1084

MORRISON D et al: Effect of high dose N-acetylcysteine on glutathioneand cysteine levels in bronchoalveolar lavage and lung tissue, 246P

MORRISON J B: Alternative and complementary medicine for asthma:correspondence, 762

MORSHUIS W J see VAN KLAVEREN R J et alMOSBECH H see DIRKSEN A et alMOSS F M see MITCHELL D M et alMOUNSEY P J see EFTHIMIOU J et alMOUSSA K et al: Blood CD4 and CD8 lymphocyte numbers incommunity acquired pneumonia, 253P

1 097

Author Index

MOWAT A G see HARGREAVES M R et alMOXHAM J see BAUDOUIN S V et al

MIER A et alMOYJ N see KAO N L et alMUKHERJEE A et al: Do body builders with large necks have sleep

apnoea? 879PMULVENNA P M see SQUIRE S B et alMUNRO N C et al: Corticosteroid improves bacterial clearance and

reduces bronchial inflammation in experimental bronchiectasis, 894PMURCH S H, MacDONALD T T, WOOD C B S, COSTELOE K L:Tumour necrosis factor in the bronchoalveolar secretions of infants withthe respiratory distress syndrome and the effect of dexamethasonetreatment, 44

MURUDKAR S N see PRABHUDESAI P P et alMUSHTAQ M, WARD S P, HUTCHISON J T, MANN J S: Multiple

cystic pulmonary hamartomas: short report, 1076MUSHTAQ M et al: An audit of lung function laboratories: the West

Midlands initiative, 848P

NNAGAI A, KANEMURA T, KONNO K: Abnormal movement of the

arytenoid region as a cause of upper airway obstruction: short report,840

NAKAGOMI K seeYAMASHITAY et alNAKAJIMA I see ABE S et alNAMNYAK S S, BLAIR A L T, HUGHES D F, McELHINNEY P,DONNELLY M R, COREY J: Fatal lung abscess due to Lactobacilluscasei ss rhamnosus: short report, 666

NATALI G see CASALE R et alNEIL P, CONGDON R: Pulmonary disease in a rural African hospital,228P

NEILD G H see LEAKER B et alNEILL P see POZNIAK A L et alNEUKIRCH F see FRETTE C et alNEWHOUSE M see GUYATT G et alNEWNHAM D M et al: Bronchodilator reversibility to low and high doses

of terbutaline and ipratropium in COPD, 255PComparison of the beta-2 adrenoceptor selectivity of inhaled fenoterol

and salbutamol, 882PNEWTON JM see TAYLOR K M G and NEWTON J MNICHOLLS D P see STANFORD C F et alNICHOLSON P S see TAYLOR R F H et alNIELSON C P see CONNOLLY M J et alNIEROP G, GIJZELW P, BEL E H, ZWINDERMAN A H, DIJKMAN

J H: Auranofin in the treatment of steroid dependent asthma: a doubleblind study, 349: correspondence, 992

NISAR M, SPENCE D P S, WEST D, HAYCOCK J, JONES Y,WALSHAW M J, EARIS J E, CALVERLEY P M A, PEARSON M G:A mask to modify inspired air temperature and humidity and its effecton exercise induced asthma, 446

NISHIMURA M, SUZUKI A, YOSHIOKA A, YAMAMOTO M,AKIYAMA Y, MIYAMOTO K, KISHI F, KAWAKAMI Y: Effect ofaminophylline on brain tissue oxygenation in patients with chronicobstructive lung disease, 1025

NISHIYA H seeYAMAGUCHI M et alNKERE U U see GILL S S et alNOSEDA A, CARPIAUX J-P, SCHMERBER J, YERNAULT J-C:Dyspnoea assessed by visual analogue scale in patients with chronicobstructive lung disease during progressive and high intensity exercise,363

NUNAN T 0 see O'DOHERTY M J et alNYGAARD S D, BERGER H A, FICK R B: Chylothorax as a

complication of oesophageal sclerotherapy: short report, 134NYMAN C R: Treatment of relapse of small cell lung cancer in selected

patients with the initial combination chemotherapy with carboplatin,etoposide, and epirubicin: correspondence, 668

0OBERWALDNER B see ZACH M S and OBERWALDNER BO'CONNELL F et al: Effect of clonidine on sensory nerve mediatedcough in guinea pigs and humans, 870P

O'CONNOR B J et al: Do cholinergic pathways take part in adenosine5'-monophosphate and sodium metabisulphite induced bronchocon-striction in asthma? 213PSodium metabisulphite induced bronchoconstriction is attenuated by a

carbonic anhydrase inhibitor, 234PO'CONNOR C M, FITZGERALD M X: Assessment of type I and type

III procollagen peptide levels in bronchoalveolar lavage fluid and serumas markers of fibrotic lung disease, 219P

O'DOHERTY M J, PAGE C J, NUNAN T 0, BATEMAN N T:Diagnostic value of lung clearance of 99mTc DTPA compared withother non-invasive investigations in Pneumocystis carinii pneumonia inAIDS: correspondence, 138

O'DRISCOLL B R, TAYLOR R J: Computerised bronchoscopy reportsand audit, 888P

O'DRISCOLL B R et al: A trial of steroid tapering in acute asthma,845PLung function and symptom scores during three years of home

nebuliser use, 863OGILVIE C M: Comroe in Philadelphia: adventitia, 297OGURA S see ABE S et alOH PI, BALTER MS: Cocaine induced eosinophilic lung disease: short

report, 478O'HICKEY S P, PITHIE A, SKINNER C: Unusual spinal tuberculosis

after adequate chemotherapy for lymph node tuberculosis in animmunocompetent man: short report, 986

O'HICKEY S P et al: Clinicopathological features of peribronchiolitis,217P

OLIVER R M et al: Abnormal right ventricular systolic and diastolicfunction in patients with pulmonary heart disease, 847P

OMENAAS E et al: Postal survey of respiratory symptoms in young adultsliving in Bergen, Norway, 884P

OMENAAS E see also GULSVIK A et alOPENSHAW P: Barcelona's asthma epidemics: correspondence, 668OPENSHAW PJ M, RECORD F M: Epithelial gamma delta T cells in

lung infection, 253PORENA C see ZUCCONI M et alORIOLA, RIBERAJ M, MORENOJ, MARTIS: Invasive aspergillosis in

a patient with idiopathic thrombocytopenic purpura without underlyinglung disease: correspondence, 328

ORMEROD L P: Results of tuberculosis contact tracing: Blackburn1982-90, 224PWhy does genitourinary tuberculosis occur proportionately less than

expected in the Indian subcontinent ethnic population in the UnitedKingdom? 876P

ORRIOLS R see MORELL F et alO'SHAUGHNESSY K M et al: Allergen evoked urinary leukotriene E,

excretion, bronchoconstriction, and airway hyper-reactivity after inhala-tion of a topically potent glucocorticoid, fluticasone propionate, 895PEffect of inhalation of the leukotriene D4 receptor antagonist ICI

204,219 on allergen evoked bronchoconstriction, 871PImaging allergen evoked airway inflammation in asthmatic patients: a

pilot study using (18F)-fluorodeoxy-glucose and positron emissiontomography, 870P

O'SULLIVAN M et al: Arachidonic acid metabolism by human bronchialepithelial cells, 243P

OSWALD N C: Little old NewYork: adventitia, 483O'TOOLE K M see SHAPIRO J M et alO'TOOLE S see JOHNSTON S L et alOVERBEEK S E see VAN BIEZEN P et alOWEN C A: Recent advances in somatic gene therapy for hereditary

respiratory diseases, 315

pPACKE G E, DOUGLAS J G, McDONALD A F, ROBINS S P, REIDD M: Bone density in asthmatic patients taking high dose inhaledbeclomethasone dipropionate and intermittent systemic corticosteroids,414

PACKE G E et al: Bronchial reactivity and immunoglobulin E concentra-tions in subjects with respiratory symptoms associated with theflowering of oilseed rape, 885PComparison of clinical features in cystic fibrosis patients with different

genotypes, 866PPADILLA I see ROMERO S et alPAGE C J see O'DOHERTY MJ et alPAGE R D see DONNELLY R J et alPAKSOY N, DEMIRCAN A, ALTINER M, ARTVINLI M: Localised

fibrous mesothelioma arising in an intralobar pulmonary sequestration:short report, 837

PALADINI P see HAID M M et alPALAZZI S see ZUCCONI M et alPANDIT A, KALRA S, WOODCOCK A: An unusual cause of bilateral

diaphragmatic paralysis: short report, 201PARARAJASINGAM C D, SITTAMPALAM L, DAMANI P, PATTE-MORE P K, HOLGATE S T: Comparison of the prevalence of asthmaamong Asian and European children in Southampton, 529

PASQUALETTI P see CASALE R et alPATEL K R: Comparison of 10 mg dry powder (DP) with 4 mg aerosol

of nedocromil sodium (NS) in exercise induced asthma (EIA), 230PPATRON M see MARTINEZ-LOPEZ M A et alPATTEMORE P K see PARARAJASINGAM C D et alPAUWELS R A see DEROM E Y and PAUWELS R APAVIA D see HASANI A et al

POLOSA R et alPAVORD I D, WISNEIWSKI A, TATTERSFIELD A E: Inhaled

frusemide and exercise induced asthma: evidence of a role for inhibitoryprostanoids, 797

PAVORD I et al: Effect of frusemide on allergen induced contractions ofpassively sensitised human bronchi in vitro, 872PFrusemide and allergen induced contractions of passively sensitisedhuman bronchi: evidence of a role for prostaglandin E2, 895P

Repeatability of measures of peak expiratory flow variability forcommunity studies, 230P

PEACOCK A Jet al: A growth factor and chemoattractant for fibroblasts(FB) is produced by endothelial cells (EC) exposed to hypoxia, 225P

PEARCE N, CRANE J, BEASLEY R, BURGESS C, JACKSON R:Prescribed fenoterol and death from asthina in New Zealand, 1981-7: a

1098

1099Author Index

further case control study: correspondence reply,

see also BREMNER P et alPEARCE N et al: Markers of risk of asthma

following a hospital admission for asthma,

Salbutamol and asthma deaths in New Zealand, 1969-1976:

control study, 210P

PEARSON M C see AL-JARAD N et al

PEARSON M G et al: Assessment of respiratory

provision of respiratory physicians, 222P

Asthma in general practice-prevalence and

Discharge and follow up of acute asthma,

see also NISAR M et alPEARSON S B see TEALE C et al

PEDERSEN S S, HOIBY N, ESPERSEN F, KOCH

in infection with mucoid Pseudomonas aeruginosa

PEEL E T: Wegener's granuloma: prognosis, treatment,

death, 217PPEIRRE C see DE LASSENCE A et al

PENA J M see MARTINEZ-LOPEZ M A et al

PENDLETON N et al: Expression of different cytoskeletal

resected non-small cell lung cancer, 249P

Expression of proliferating cell nuclear antigen

tracheobronchial epithelium, 249P

PEPIN L, FERRETTIG, VEALE D, ROMAND

BRAMBILLA C, LEVY P A: Somnofluoroscopy,

tomography, and cephalometry in the assessment

obstructive sleep apnoea, 150

PEPKE-ZABAJ et al: Hypoxia directly causes pulmonary

muscle to relax in man, 224P

PERRY D see JOHNSTON S L et al

PERRY FE et al: Characterisation of the respiratory

produced by S. pneumoniae, 869P

Interference of S. pneumoniae with the oxidative response

role of oxidation of cytochrome C by S. pneumoniae,

Stimulation of the oxidative response of neutrophils

pneumoniae, 870P

Susceptibility of S. pneumoniae to killing by reactive

869PPERSSON C G A, SVENSSON C, GREIFF L,

WOLLMERP, ALKNER U, ERJEFALT I: The use

the inflammatory response of the respiratory tract: editorial,

PETERS A M see WHYTE M K B etal

PETERS MJBRESLIN A B X, BEREND N: Effects of inhalation

methionyl-leucyl-phenylalanine in the well elderly

with chronic bronchitis, 279

BRESLIN A B X, KEMP AS, CHU J, BEREND

effects of inhalation of N-formyl-methionyl-leucyl-phenylalanineman, 284: correspondence repty, 763

PETERS P, TROTTER S E, SHEPPARD M

Primary leiomyoma of the pulmonary vein: short

PETERS S A see LAMBERT E J et at

PETERS S E et at: Absence of latentPneumocystis cariniimortem lung samples, 856P

PETROU M et at: Treatment of tracheobronchial

bronchoscopic diathermy resection: a cheap and

886PPFITZENMEYER P, FOUCHER P, PIARD F, COUDERT

M L, GABEZ P. LACROIX MABILLE J-P, CAMUS

pneumonitis: a report on eight patients,

PHAGOO S B, WILSON N M, SILVERMAN

methacholine challenge in asthmatic children measured

transcutaneous oxygen tension, 804

PHELAN P D see CHETCUTI P et

PIARD F see PFITZENMEYER P et

PICADO C: Barcelona's asthma epidemics: clinical

findings, 197: correspondence, 843

see atso LLOBERES P et at

LUENGO M and PICADO C

PLAZA V et at

PICKERING C A C see FISHWICK D and PICKERING

KALRA Set al

PIN I, GIBSON P G, KOLENDOWICZ R, GIRGIS-GABARDO

DENBURG J A, HARGREAVE F E. DOLOVICHsputum cell counts to investigate airway inflammation

PITHIE A see O'HICKEY S P et at

PITHIE A D, RAHELU M, KUMARARATNE

GASTON J S H, ILES P B, INNES J A, ELLIS

cytolyticT cells in individuals infected by Mvcobacterium

vaccinated with BCG, 695

PITKIN A D et at: Changing patterns of respiratory disease in HIV

positive patients 1986-7 and 1990-1, 854P

PITT T L see TAYLOR R F H et at

PLANES C, KLEINKNECHT D, BRAUNER BATTESTI

KEMENYJ-L, VALEYRE D: Diffuse interstitial lung

amyloidosis: short report, 323

PLASSMAN B L see GORMAN R B et at

PLAZA V, CASALS F, ALONSO A, PICADO C: Platelet kinetics inasthmatic patients with and without aspirin intolerance, 533

POLLOCK J S S et al: Improved recovery after propofol sedation foroutpatient bronchoscopy, 246P

POLOSA R, HASANI A, PAVIA D, AGNEW J E, LAI C K,CLARKE SW, HOLGATE S T: Acute effect of inhaled bradykinin on

tracheobronchial clearance in normal humans, 952POLOSA R et al: Cyclooxygenase inhibition modulates the change in

bronchial reactivity to methacholine with inhaled frusemide in normalsubjects, 853PModulation of tracheobronchial clearance by inhaled bradykinin and

(desArg9)-bradykinin in normal subjects, 860PTime course of change in bronchial reactivity to adenosine 5'-mono-

phosphate with inhaled loop diuretics in asthma, 872PDiagnostic value ofACTH, CRH and beta-endorphin concentrations as

tumoral markers in the bronchial lavage fluid of patients with lungcancer, 887P

POOLE C see LANES S F et al

PORTER D see MARSHALL D A S et alPOSTMA D S see BRAND P L P et al

WEMPEJ B et alPOTTIER A C see ANDERSON H R et al

POWELL RJ see EVANS S A et alPOWER C et al: How "normal" is a normal healthy subject? 240PPOWNEY J, SCOTT A D, GEORGE P J M, FENECK R 0,WRIGHT J, BARNES N C: Preoperative laser therapy in a patient withresectable bronchogenic carcinoma and severe coronary artery disease:short report, 1075

POZNIAK A L, LATIF A S, NEILL P, HOUSTON S, CHEN K,ROBERTSON V: Pulmonary Kaposi's sarcoma in Africa, 730

PRABHUDESAI P P, MAHASHUR A A, MURUDKAR S N, AJAY R:Percutaneous visceral pleural biopsy with fenestrated cup biopsyforceps: technical note, 753

PRAKASH D et al: Malignant pleural mesothelioma: role of the surgeon,851P

PRATS E see MANRESA F et alPRENTICE H G see MILBURN H J et al

PRIDE N B: Forced oscillation techniques for measuring mechanicalproperties of the respiratory system, 317

PRYNNE M see LOCK S H et alPUGIN J, AUCKENTHALER R, DELASPRE 0, VAN GESSEL E,SUTER P M: Rapid diagnosis of Gram negative pneumonia by assay ofendotoxin in bronchoalveolar lavage fluid, 547

PUJOL A see MORELL F etal

QQING F et al: Alveolar beta-adrenergic receptor density in asthmatic

subjects before and during corticosteroid and beta-agonist therapy:preliminary studies using positron emission tomography and 11 C-S-CGP 12177, 871P

QUANJER P H: A10 year follow up of 180 adults with bronchial asthma:factors important for the decline in lung function: correspondence, 484seealso BRAND P L P etal; MERKUS PJ F M etal

QUIGLEY C etal: Audit of patient education in asthma management,239P

QUINN A G see BOURKE S J etalQUIRALTE J see MARTINEZ-LOPEZ M A etal

QUIRK F H, JONES PW: Nocturnal symptoms, morning symptoms, andnight time inhaler use in patients with asthma, 861P

RRAHELU M see PITHIE A D etalRAHMAN A RA, McDEVITT D, STRUTHERS A D, LIPWORTH BJ:

Sex differences in hypokalaemic and electrocardiographic effects ofinhaled terbutaline, 1056

RAINER T et at: Determinants of inspiratory flow rate (IFR) throughDiskhalers, 239P

RAJAKULASINGAM K et at: Changes in mucosal blood flow and airwaysresistance after nasal challenge with bradykinin and histamine, 894PComparative nasal effects of bradykinin and histamine: influence on

nasal airways resistance and plasma vascular leakage, 232PCross refractoriness between bradykinin and hypertonic saline chal-

lenges in asthma, 873PFactors determining bradykinin responsiveness and refractoriness in

asthma, 856PRepeatability and reversibility of bradykinin induced nasal symptomsand plasma leakage, 232P

The role of histamine and cholinergic pathways on bradykinin inducednasal responses, 894P

R AMAGE L et a t:Chronic dosing w ithinhaled salmeterol in exerciseinduced asthma (EIA), 255P

REES J et at: AIDS related primary intrathoracic lymphoma, 223PREID D M see PACKE G E et atRENNICK R E, LOESCH A, BURNSTOCK G: Endothelin, vasopres-

sin, and substance P like immunoreactivity in cultured and intactepithelium from rabbit trachea, 1044

RENWICK P et at: Endoscopic Nd YAG laser treatment (ELT) forobstructive tracheal lesions, 250P

Author Index1100

RESTRICK L J et al: Effect of ambulatory oxygen treatment on symptoms

and exercise capacity in chronic heart failure, 858PPrescription of oxygen concentrators: review of patients with SaO,

above 910% at follow up assessment, 847P

Oxygen concentrators: assessment for prescription and reassessment,

222PREYNOLDS S P et al: The early immune response in extrinsic allergic

alveolitis as assessed by analysis of bronchoalveolar fluid, 214P

RHODES C G see BRUDIN L H et alRIBERAJ M see ORIOL A et alRIBET M: Surgical treatment of carcinoma of the oesophagus and

Laurence O'Shaughnessy: correspondence, 842

RICHARDS K et al: Descriptive epidemiology of airway hyperreactivity to

methacholine in a random adult population sample, 885P

RICHMOND GW see KAO N L et alRICHMOND I et al: Bronchus associated lymphoid tissue: does it exist in

humans? 241PBronchus associated lymphoid tissue: a feature of airway immuno-

pathology in smokers, 886PRICHON C A see TSCHOPPJ M et alRITCHIE A J, DANTON M, GIBBONSJ R P: Prophylactic digitalisation

in pulmonary surgery, 41

ROBERTS AW see BOOTS R J et alROBERTS C M et al: Obstructive sleep apnoea in single lung transplant

recipients, 878PROBERTSJ A et al: Effects of a six week course of salmeterol on bronchial

reactivity, 230Psee also MONTEFORT S et al

ROBERTSON V see POZNIAK A L et alROBINS S P see PACKE G E et alROBINSON D: Diagnostic value of lung clearance of 99mTc DTPA

compared with other non-invasive investigations in Pneumocystis carinii

pneumonia in AIDS: correspondence reply, 138

ROBINSON D S et al: Activation of CD4+ T cells and increased IL-4, IL-

5 and GM-CSF mRNA positive cells in bronchoalveolar lavage (BAL)

24 hours after allergen inhalation challenge of atopic asthmatic patients,

852PLocalisation of mRNA for IL-4 and IL-5 to T cells in bronchoalveolar

lavage fluid in atopic asthma, 212P

ROBSON M, ABBOTT J, WEBB K, DODD M, WALSWORTH-BELL

J: A cost description of an adult cystic fibrosis unit and cost analyses of

different categories of patients, 684

ROCA J, HERAS M, RODRIGUEZ-ROISIN R, MAGRINA J, XAU-

BET A, SANZ G: Pulmonary complications after long term amiodar-

one treatment, 372see also AGUSTI C et al; RODRIGUEZ-ROISIN R et al

ROCHEW R see MONTEFORT S et alRODENHUIS S see VLASVELD L Th et alRODENSTEIN D 0 see COLLARD Ph et alRODRIGUEZ-ROISIN R, AGUSTI A G N, ROCA J: The hepato-

pulmonary syndrome: new name, old complexities: editorial, 897

see also AGUSTI C et al; ROCA J et alROGERS D F: New perspectives on basic mechanisms in lung disease:

introduction, 1063see also ALTON EW FW et al

ROGERS P see CIMOLAI N et alROGERS T KMORICE A H: ANP relaxes resistance vessels at pathophysiological

concentrations, 225PMORICE A H: Effects of chronic hypoxia on contractility of pulmonary

resistance vessels, 225PMORICE A H: Inhibition of hypoxic vasoconstriction in isolated small

pulmonary arteries by ANP, 892P

ROGERS T K et al: Sputum induction in the cytological diagnosis of

bronchogenic carcinoma, 887PROLLES C J see LAMBERT E J et alROMAND P see PEPIN J L et alROMERO S,VELA P, PADILLA I, ROSAS J, MARTIN C, ARANDA I:

Pleural effusion as manifestation of temporal arteritis: short report, 398

ROMNEY B M see SHAPIRO J M et alRONA R J, CHINN S: Lung function, respiratory illness, and passive

smoking in British children, 220Psee also CHINN S and RONA R J

ROODA H M E see MERKUS P J F M et alROSAS J see ROMERO S et alROSELL A see FIZ J A et alROSS S J: Outcome of wheeze in childhood: educational attainment and

employment 25 years later, 253PROSSINI M J see TSCHOPP J M et alROUTLEDGE P A see MORRISON D et alRUBENS M B see AL-JARAD N et alRUDD R see BOTHAMLEY G H et alRUDD R M see AL-JARAD N et al

GEORGE P J M et alRUIZ J see FIZ J A et alRUSSELL P et al: Effect of hyperinflation on pulmonary artery pressure

in chronically hypoxic rats, 892P

RUTLAND J see DE IONGH R et al

SSADIQ S see AL-MAJED S et alSAHIN A A see COPLU L et al

KALYONCU A F et alSAKAMOTO S see FUJIMURA M et alSAKAMOTO T et al: Evaluation of a bradykinin antagonist (HOE 140)

against bradykinin and platelet activating factor induced airway respon-ses in the guinea pig, 241P

SALMERON S see SITBON 0 et alSANTIS G K see UDWADIA Z F et alSANZ G see ROCA J et alSARNAIK R M: Randomised clinical trial of chest drainage systems:

correspondence, 1086SCADDING G: Surgery at the Brompton Hospital in 1932-3: adventitia,549The early days of lobectomy for bronchiectasis: adventitia, 789

SCHMEKEL B, BOS J A H, KHAN A R, WOHLFART B, LACH-MANN B,WOLLMER P: Integrity of the alveolar-capillary barrier andalveolar surfactant system in smokers, 603

SCHMERBER J see NOSEDA A et alSCHOFIELD D et al: Glutathione state in adults with cystic fibrosis,866P

SCHOLS A M W J: Body composition and exercise performance inpatients with chronic obstructive pulmonary disease (COPD): corre-spondence reply, 66

SCHREUR H JW, STERK PJ,VANDERSCHOOT J,VAN KLINK H CJ, VAN VOLLENHOVEN E, DIJKMAN J H: Lung sound intensity inpatients with emphysema and in normal subjects at standardisedairflows, 674

SCHRIER A C see DEKKER F W et alSCOTT A D see POWNEY J et alSCOTT S see SINGH S J et alSEALE J see SPRING J et alSEATON A: How progressive is bronchopulmonary aspergillosis? 854PSEATON E D et al: Pressurised metered dose inhaler technique: howgood are general practitioners? 237P

SEEAR M see CIMOLAI N et alSELBY CDROST E, MACNEE B: Haematological effects of inhalation of

N-formyl-methionyl-leucyl-phenylalanine in man: corerspondence,763

SUDLOW M F: Management of spontaneous pneumothoraces: auditof process, 887P

SELBY C et al: Impaired neutrophil rheology: an early event in acute lunginjury, 244P

SELCUK Z T see COPLU L et alKALYONCU A F et al

SELL L et al: Communicating the diagnosis of lung cancer, 250PSEMPLE S J G see MILLER R F et alSERGYSELS R see MICHEL 0 et alSESBOUE R see FRETTE C et alSHAHEEN M Z et al: Phase angle changes as a measure of paradoxical

breathing during sleep related apnoeas/hypopnoeas in patients withsleep apnoea syndrome, 879PRandomised double blind cross over trial of immunoglobulin replace-ment therapy in patients with severe asthma, 254P

SHAHMANESH M, DRAKE S, WHITE D, HORTON A, EVANS J,JONES G S: Persistent alveolar increased permeability to 99mTcDTPA in patients with advanced HIV infection: correspondence, 575

SHALE D J: Scientific updates in respiratory medicine: introduction,127The cost of care in cystic fibrosis: editorial, 673Viral infections: a role in the lung disease of cystic fibrosis: editorial,69see also ELBORN S et al; FAUX J A et alSHAMSSAIN M H: Pulmonary function and symptoms in workers

exposed to wood dust, 84SHAPIRO J M, ROMNEY B M, WEIDEN M D, WHITE C S,O'TOOLE K M: Rhodococcus equi endobronchial mass with lungabscess in a patient with AIDS: short report, 62

SHARPLES L D et al: Predictors of survival of patients awaiting heart-lung transplantation in cystic fibrosis and assessment of postoperativesurvival, 247P

SHAW R J et al: Anti-inflammatory drugs increase mRNA of the growthfactor platelet derived growth factor-B in alveolar macrophages, 893PAssessment of PCR amplification of IS611 0 DNA in blood, as a

diagnostic test for tuberculosis, 876Psee also WALKER D A et al

SHEEDY W et al: Hypobaric and normobaric hypoxia in rats, 892PSHELDON C D, KING K, COCK H, WILKINSON P, BARNES N C:

Notification of tuberculosis: how many cases are never reported, 1015SHEPPARD M N, HARRISON N K: Lung injury, inflammatory

mediators, and fibroblast activation in fibrosing alveolitis, 1064see also PETERS P et al

Author Index

SHINER R J et al: Methotrexate in steroid dependent asthma: long term

results, 254PSHIRAKUSA T see UEDA H and SHIRAKUSA TSHNEERSON J: Transtracheal oxygen delivery: new techniques, 57SIBBALD B, ANDERSON H R, McGUIGAN S: Asthma and employ-ment in youngaduits, 19

SICILIAN! L see JAVAHERI S and SICILIAN LSILVERMAN M see PHAGOO S B et alSILVERSTONE E J see JISHI F et alSIMMONDS E J see CONWAY S P et alSIMONDS A K see EILIOTT MW et al

UDWADIA Z F et alSIMPSON K, KILLIAN K, McCARTNEY N, STUBBING D G,JONES N L: Randomised controlled trial of weightlifting exercise inpatients with chronic airflow limitation, 70

SINCLAIR D G et al: Screening for asthma in the British army, 890PThe effect of pulmonary infection on airway transepithelial potential

difference (TEPD) in ventilated patients, 233PSINCLAIR DJM see SKINNERJ S and SINCLAIR D J MSINGER J see GUYATT G et alSINGH S J, MORGAN M D L, SCOTTS,WALTERS D, HARDMANA E: Development of a shuttle walking test of disability in patients withchronic airways obstruction, 1019

SINGH S J et al: Comparison of patients' performance on the shuttlewalking test and the six minute walking test, 236P

SISSONS C E see JISHI F et alSITBON 0, SALMERON S, DUROUX P, CAQUET R: Auranofin in

steroid dependent asthma: correspondence, 992SITTAMPALAM L see PARARAJASINGAM C D et alSIVARDINE Z et al: Comparison of the bronchodilator potencies and

effects on bronchial reactivity of nebulised salbutamol and adrenaline inmild asthmatic subjects in vivo, 874P

SKINNER C see O'HICKEY S P et alSKINNERJ S, SINCLAIR DJ M: Fatal mediastinal compression as a late

complication of surgical plombage: short report, 321SLUITER H J see BRAND P L P et alSMIRNE S see ZUCCONI M et alSMITH B J: Inhaled corticosteroids: benefits and risks: correspondence,

1084SMITH D E, FORBES A, DAVIES S, BARTON S E, GAZZARD B G:

Diagnosis of Pneumocystis carinii pneumonia in HIV antibody positivepatients by simple outpatient assessments, 1005

SMITH D L et al: Chronic supplemental enteral nutrition via the

nasogastric route in cystic fibrosis, 866PCystic fibrosis related diabetes mellitus: prevalence and insulin respon-

ses in adults, 866PIncreased incidence of Pseudomonas cepacia infection in an adult CF

centre: management issues, 866PSMITH E C, KENDRICK A H: Asthma policy in state schools of 14

education authorities in the UK, 890PSMITH I E see TALBOT D C and SMITH I ESMITH P see JOHNSTON S R D et alSMOLINSKY A, ARAV R, HEGESH J, LUSKY A, GOOR D A: Surgical

closed pulmonary valvotomy for critical pulmonary stenosis: implica-tions for the balloon valvuloplasty era, 179

SMYTH ET et al: Effect of addition of increasing doses of salbutamol to

salmeterol, 855PSNASHALL P D et al: Bronchial responsiveness to intravenous adrenaline

in normal, atopic, and asthmatic man, 256PSOBRADILLO V, ZALACAIN R, CAPELASTEGUI A, URESANDI F,CORRAL J: Antibiotic treatment in pneumonia due to Q fever, 276

SOLOMON J A see AINSLIE G M et alSONCUL H see ERSOZ A et alSOUHAMI R L: The antigens of lung cancer, 53SOUSA A R et al: Up regulation of GM-CSF expression in the bronchial

epithelium of asthmatic patients shown by immunohistochemistry,852P

SOUTAR C A see CULLEN RT et alSOUTHCOTT A M et al: Interleukin-8 mRNA expression in sarcoidosis,215P

S0YSETH V see KONGERUD J et alSPEIZER F E see GULSVIK A et alSPENCE D P S, BENTLEY S, EVANS D H, MORGAN M D L: Effect

of methacholine induced bronchoconstriction on the spectral character-istics of breath sounds in asthma, 680see also NISAR M et al

SPENCE D P S et al: Asthma drug and peak flow meter prescribing ingeneral practitioner practices, 884PEffect of oxitropium bromide and salbutamol on oxygen desaturation

and breathlessness during six minute walking tests in chronicobstructive pulmonary disease, 211P

Influence of mechanical limitation on the ventilatory and sensory

responses to carbon dioxide and hypoxia, 211PPredictors of symptomatic and functional benefit after oxitropium in

COPD, 865PRelation between breath sounds and airflow obstruction during exacer-

bations of asthma, 888P

Relationship between wheeze, airflow and lung volume during metha-choline induced bronchoconstriction in asthmatic subjects, 253P

Tuberculosis and poverty, 849PSPIRO S: Supplements for Thorax: editorial note, 143SPITERI M A see HASANI A et alSPITTLE M F see MILLER R F et alSPRING J, JOHNSTON S R, SEALE J, IND PW: Failure of salmeterol

to inhibit circulating white cell responses and bronchoconstrictioninduced by platelet activating factor, 948

SPRING J et al: PAF induced bronchoconstriction and leucopenia are notinhibited by salmeterol, 255P

SQUIRE S B, LIPMAN M C I, BAGDADES E K, MULVENNA P M,GRUNDY J E, GRIFFITHS P D, JOHNSON M A: Severe cyto-megalovirus pneumonitis in HIV infected patients with higher thanaverage CD4 counts, 301

SRIDHAR M K et al: Estimation of resting energy expenditure (REE) inpatients with chronic lung disease: comparison of a ventilated hood andmouthpiece system, 864PUse of transcutaneous oxygen and carbon dioxide tensions for assessing

gas exchange during exercise, 848PSRIKRISHNA S V: Pleural abrasion: a new method of pleurodesis:

correspondence, 138STANFORD C F, MARTIN B, NICHOLLS D P, WATSON D: Lung

function testing in adults with preferential nasal breathing, 719STANFORD J L see GRANGE J S et alSTAPLES B et al: Respiratory effects of air pollution, 885PSTEEL D M et al: Second messenger regulation of the isolated chloride

current in human airway epithelium, 860PSecond messenger regulation of the isolated chloride current in asodium absorbing epithelium, 233P

STENTON S C et al: Asthmatic symptoms, airway responsiveness (AR)and appreciation of bronchoconstriction, 846PTechnique for double blind inhalation challenge testing with glutar-

aldehyde, 889PThe size of statistically significant late asthmatic reactions (LARs),855P

STERK P J see DEKKER F W et alSCHREUR H JW et al

STERN M et al: Vitronectin receptor mediates macrophage phagocytosisof apoptotic eosinophils, 240Psee also DE LASSENCE A et al

STEVEN M H et al: Home sleep studies with Mesam 4: feasibility,accuracy and diagnostic value, 234Psee also UDWADIA Z F et al

STEVENSON R D et al: Changes in neutrophil motility, shape andadhesiveness produced by a glucocorticoid induced peptide, 860P

STEWART A G et al: Hypoxia and sodium retention in chronicobstructive pulmonary disease (COPD), 847PHypoxia and water retention in chronic obstructive pulmonary disease(COPD), 846P

STONE R A et al: 5-Hydroxytryptamine and sensitivity of the humancough reflex, 895PCough responses to chloride deficient challenge are not inhibited by

acetazolamide, 234PSerotoninergic mechanisms influence control of the cough reflex in the

guineapig, 234PSTONE T N see BAZUAYE E A et alSTONEMAN S A T, EARIS J E: Measurement of attenuation ofpseudolung sounds by animal lung and chest wall, 880P

STORM H K R, KRASNIK M, BANG K, FRIMODT-MOLLER N:Treatment of pleural empyema secondary to pneumonia: thoraco-centesis regimen versus tube drainage, 821

STRACHAN D P see ANDERSON H R.et alSTRADLING J R see DAVIES R J 0 et alSTRICKLAND B: Practice makes perfect: adventitia, 320

see also AL-JARAD N et alSTRUTHERS A D see RAHMAN A R A et alSTUBBING D G see SIMPSON K et alSTURROCK R D see MARSHALL D A S et alSUKOH N see ABE S et alSULLIVAN P J, CURRIE D, COLLINS J V, JOHNSTONE D J,MORGAN A: Vertebral osteomyelitis presenting with pleuritic chestpain and bilateral pleural effusions: short report, 395

SUMMERS Q A see JOHNSTON S L et alSUTER P M see PUGIN J et alSUZUKI A see NISHIMURA M et alSVENSSON C see PERSSON C G A et alSWAMI A, KEOGH B F: The injured lung: conventional and novel

respiratory therapy, 555SYKES A P, AYRES JG: Incidence of side effects in brittle asthma patients

taking infused terbutaline with and without oral terbutaline, 256P

TTAKAO M et al: Changes of bronchial mucosal blood flow after lung

transplantation, 877PTAKEDAT seeYAMASHITAY et alTAKEKAWA H see ABE S et al

1 101

Author Index

TAKISHIMA T see MIURA C et alTALBOT D C, SMITH I E: New drugs in lung cancer, 188TAMM M et al: Early bacterial and fungal infections in lung transplanta-

tion, 885PTASKAR V et al: Breath holding time in normal subjects, snorers, and

sleep apnoea, 880PTATTERSFIELD A E see PAVORD I D et alTAYLOR I K et al: Urinary leukotriene E4 (LTE4) excretion in exercise

induced asthma (EIA), 241PTAYLOR I K sec also WALKER D A et alTAYLOR K M G, NEWTON J M: Liposomes for controlled delivery of

drugs to the lung: editorial, 257TAYLOR R F HHODSON M E: Cystic fibrosis: antibiotic prescribing practices in theUnited Kingdom and Ireland, 252P

MORGAN D W, NICHOLSON P S, MACKAY I S, HODSON M E,PIT1T T L: Extrapulmonary sites of Pseudonionas aeruginosa in adultswith cystic fibrosis, 426

TEALE C, CUNDALL D B, PEARSON S B: School microepidemic oftuberculosis: correspondence, 208

TEALE C et al: Side effects of anti-tuberculous therapy in the elderly,875PTerfenadine in nocturnal asthma, 230P

THATCHER N: Haematopoietic growth factors and lung cancer treat-ment, 119

THIEN F C K et al: Effects of dietary fish oil supplementation on seasonalasthma in pollen sensitive asthmatics, 885PEffects of exogenous eicosapentaenoic acid on in vitro eosinophil

generation of leukotriene C, 241PTHOMAS V E et al: Ipratropium bromide delivered orally by metered

dose inhaler does not decrease salivary flow in normal subjects, 891PTHORNTON J C see KILBURN K H et alTHORNTON K see KILBURN K H et alTOCILJ J see DUJIC Z et alTOMASHEFSKI J F see BLOODWORTH J and TOMASHEFSKI J FTOMLINSON M C see MILLER R F et alTOSTESON T see GULSVIK A et alTREACHER D F see LEACH R M and TREACHER D FTRIGG C J et al: Radiographic chemical sensitisation in a radiographer,229P

TROTTER S E see PETERS P et alTSANG G M K, WATSON D C T: The practice of cardiothoracic

surgeons in the perioperative staging of non-small cell lung cancer, 3TSANG K et al: Culture filtrates obtained from growth of non-typable

Haeniophilus influenzae with subminimal inhibitory concentrations ofantibiotics cause less ciliary slowing of human respiratory epithelium invitro, 868PThe protective effects of subminimal inhibitory concentrations of

antibiotics on non-typable Haeniophilus influenzae (NTHi) infectionof human respiratory epithelium in vitro, 859P

TSCHOPP JM, ROSSINI M J, RICHON C A, LETOVANEC N, JORISF, FREY J G, KAELIN R M: Retroperitoneal silicosis mimickingpancreatic carcinoma in an Alpine miner with chronic lung silicosis:short report, 480

TUNAOGLU S see ERSOZ A et alTWORT C H C et al: Human airway smooth muscle (HASM): the Ca2+

store during sustained agonist activation, 213Psee also LEACH R M et al

TYDEMAN D E: Evaluation of physiotherapy given before electiveabdominal surgery for patients who have no history of respiratorydisease, 249P

UUDWADIA Z F, SANTIS G K, STEVEN M H, SIMONDS A K: Nasal

ventilation to facilitate weaning in patients with chronic respiratoryinsufficiency, 715

UEDA A see HONDA I et alUEDA H, SHIRAKUSA T: Carinal transplantation, 968UEIKI J et al: In vivo quantification of pulmonary beta-adrenoceptor

density using 1IC-S-CGP 12177 and positron emission tomography(PET), 853P

UEKI J et al: Evaluation of diaphragmatic thickness-respiratory musclestrength relationship by ultrasound, 215P

UENOT see HONDA I et alULRIK C S, BACKERV, DIRKSEN A: A 10year follow up of 180 adultswith bronchial asthma: factors important for the decline in lungfunction, 14: correspondence, 484

URESANDI F see SOBRADILLO V etal

vVALEYRE D see PLANES C etalVALIND S0 seeBRUDIN L H etalVAN BIEZEN P, OVERBEEK S E, HILVERING C: Cystic fibrosis in a

70 year old woman: short report, 202VAN DEN BOSCH see HAITJEMA T etalVAN DER MARK TW seeWEMPE JB etal

VAN DER SCHANS C P: Effect of positive expiratory pressure breathingin patients with cystic fibrosis: corresponidenice, 66

VAN ESSEN-ZANDVLIET E E M see MERKUS P J F M et alVAN GESSEL E see PUGIN J et alVAN KLAVEREN R J, MORSHUIS W J, LACQUET L K, COX A L,FESTEN J, HEYSTRATEN F M J: Congenital bronchial atresia withregional emphysema associated with pectus excavatum: short report,1082

VAN KLINK H C J see SCHREUR H JW et alVAN TEIJLINGEN E, FRIEND J A R: Children and smoking: theproblem and the way forward: editorial, 485

VAN VELZEN-BLAD H see HAITJEMA T et alVAN VOLLENHOVEN E see SCHREUR H JW et alVANDERSCHOOT J see SCHREUR H JW et alVARNEY V A et al: Effect of grass pollen immunotherapy on cutaneous

mast cell subtypes and immediate sensitivity to allergen and histamine,871PEffect of grass pollen immunotherapy on cytokine mRNA expression

during allergen induced late cutaneous responses, 871PVATHENEN A S et al: Is the variation in bronchial reactivity greater in

patients with severe unstable asthma compared with patients withmilder stable asthma? 855P

VAZQUEZ J J see MARTINEZ-LOPEZ M A et alVAZQUEZ R see CORZO J E et alVEALE D et al: Survival in non-small cell lung cancer in relation to

epidermal growth factor receptor expression, 860Psee also PEPIN J L et al

VELA P see ROMERO S et alVENKATESAN P, MACFARLANE J T: Role of pneumococcal antigen

in the diagnosis of pneumococcal pneumonia: editorial, 329VESTAL R E see CONNOLLY M J et alVLASVELD LTh, DELEMARRE J F M, BEYNEN J H, RODENHUIS

S: Invasive aspergillosis complicated by subclavian artery occlusion andcostal osteomyelitis after autologous bone marrow transplantation: shortreport, 136

VOCK P see GUGGER M and VOCK P

WWAHEDNA I et al: Pulmonary lymphangioleiomyomatosis: a case control

study of possible aetiological factors, 217PWAKEFIELD A E, HOPKIN J M: Molecular genetic analysis shows

Pneunzocystis cariinz is closely related to the ustomycetous red yeastfungi, 856P

WAKEFIELD A E et al: DNA amplification for Pneunrocvstis cariliz froma saline mouth rinse, 857P

WALESBY R K see GILL S S et alWALKER A M see LANES S F et alWALKER D A, TAYLOR I K, MITCHELL D M, SHAW R J:Comparison of polymerase chain reaction amplification of two myco-bacterial DNA sequences, IS6110 and the 65kDa antigen gene, in thediagnosis of tuberculosis, 690

WALKER P E, FRITH P A: Chronic airflow limitation (CAL): cognitivefunctioning, pulmonary physiology and quality of life, 865P

WALKERW S see KERR K M et alWALLACE W A H, GILLOOLY M, LAMB D: Intra-alveolar macro-

phage numbers in current smokers and non-smokers: a morphometricstudy of tissue sections, 437see also CAREY F A et al

WALLER R E see MAYNARD R L and WALLER R EWALSH L J et al: Audit of pleural biopsies: an argument for setting up a

pleural biopsy service, 849PPneumonia after stroke, 874P

WALSHAW M J see NISAR M et alWALSHE A D P, DOUGLAS J G, KERR K M, McKEAN M E,GODDEN D J: An audit of the clinical investigation of pleural effusion,734

WALSWORTH-BELL J see ROBSON M et alWALTERS D see SINGH S J et alWALTERS E H: Bronchoalveolar lavage as a research tool: correspondenice

reply, 207WALTERS E H et al: Salmeterol xinafoate: an extended comparison with

salbutamol in patients with moderate asthma receiving prophylactictherapy, 883PSalmeterol xinafoate: a comparison with salbutamol in patients withmoderate asthma receiving prophylactic therapy, 883P

WARBURTON C J et al: Repeatability of histamine bronchial challenge insymptom free textile workers as measured by dose response, 889P

WARD A see BAUDOUIN S V et alWARD C ct al:How much fluid stays in the lung after bronchoalveolar

lavage? 887PWARD K A etal: Obligate nasal breathing in adults, 236PWARD S P see MUSHTAQ M etalWARDLE E N: Cellular mechanisms of acute lung injury: implications for

future treatment in the adult respiratory distress syndrome: correspond-ence, 668

WARREN P M et al: Effect of subanaesthetic dose of halothane on the

1102

Author Index

ventilatory response to sustained hypoxia in normal subjects, 879Psee also JEFFREY A A et al; JEFFREY A A and WARREN P M;McLEAN A et al

WARSHAW R J see KILBURN K H et alWATANABE N see ABE S et alWATERHOUSE J C et al: A clinical description of those prescribed

oxygen concentrators in England and Wales, 221PWATERHOUSE J et al: Breathlessness, hypoxaemia, and survival in acommunity study, 847PCommunity management of long term domiciliary oxygen therapy: an

outline plan, 864PWATHEN C G see KERR K M et alWATSON D see STANFORD C F et alWATSON D C T see TSANG G M K and WATSON D C TWATSON L see EVANS S A et alWATURA R see HUSSAIN S F et alWEBB K see ROBSON M et alWEDZICHA J A see ELLIOTT MW et al

LOCK S H et alWEI S M see FRETTE C et alWEIDEN M D see SHAPIRO J M et alWEIR D CBURGE P S: Relation between diurnal variability in peak expiratory

flow (PEF), symptoms, reversibility of FEVy, and bronchial respon-siveness in patients with severe chronic airflow obstruction (CAO),865P

BURGE P S: Significance of symptoms of bronchial irritability inpatients with non-asthmatic chronic airflow obstruction (CAO),865P

WEIR D C et al: Observations on decline in FEV, in patients with chronicairflow obstruction (CAO): relation to acute steroid response, bronchialresponsiveness (BHR), and treatment with inhaled corticosteroids,221P

WEISS S T see GULSVIK A et alWELLS A U, HANSELL D M, CORRIN B, HARRISON N K,GOLDSTRAW P, BLACK C M, DU BOIS R M: High resolutioncomputed tomography as a predictor of lung histology in systemicsclerosis, 508: correction, 738

WELLS A U et al: High resolution computed tomography appearancescorrelate with bronchoalveolar lavage cell profiles in fibrosing alveolitis,218PHRCT appearances can identify labile disease in fibrosing alveolitis

associated with systemic sclerosis, 218PRelationship between 99mTc DTPA clearance and extent of disease

assessed by HRCT inpatients with fibrosing alveolitis, 218PWEMPE J B, POSTMA D S, BREEDERVELD N, KORT E,VAN DERMARK T W, KOETER G H: Effects of corticosteroids on broncho-dilator action in chronic obstructive lung disease, 616

WEST D see NISAR M et alWESTERMANN C J J, JANSSEN J P: Bronchial compression as a result

of lung herniation after pneumonectomy: correspondence, 208WESTON M, GODDARD P: Pathological assessment of mediastinallymph nodes in lung cancer: implications for non-invasive mediastinalstaging: correspondence, 842

WEYNANTS P see COLLARD Ph et alWHITE C S see SHAPIRO J M et alWHITE D see SHAHMANESH M et alWHITE J E S et al: Effects of nasal CPAP on nocturnal profiles of

metabolic hormones in subjects with obstructive sleep apnoea (OSA),235P

WHHITE R J see DILWORTH J P et alWHYTE M K B, PETERS A M, HUGHES J M B, HENDERSON B L,BELLINGAN G J, JACKSON J E, CHILVERS E R: Quantification ofright to left shunt at rest and during exercise in patients with pulmonaryarteriovenous malformations, 790

WILKINSON J R et al: Paradoxical bronchoconstriction associated withsalmeterol metered dose inhaler, 254P

WILKINSON P see SHELDON C D et alWILSON G E et al: Insertion of self expandable metal stents under direct

vision via a fibreoptic bronchoscope: preliminary experience, 250PWILSON JW et al: Subepithelial fibrosis in asthmatic airways, 854PWILSON N M see PHAGOO S B et alWISE R see BALDWIN D R et al

WISNIEWSKI A see PAVORD I D et alWOHLFART B, see SCHMEKEL B et alWOLLMER P see PERSSON C G A et al

SCHMEKEL B et alWONG C S et al: Effects of budesonide and terbutaline on bronchial

reactivity to allergen in subjects with mild atopic asthma, 231PRepeatability of the early response to allergen in subjects with mild

atopic asthma, 231PWONG P S et al: Long term follow up of pleuroperitoneal shunts for

malignant pleural effusion, 861PWOOD A M et al: Active chloride transport in the sheep tracheal

epithelium is regulated by prostaglandins, 233PWOOD C B S see MURCH S H et alWOODCOCK A see PANDIT A et alWOODCOCK A A see KALRA S et alWOODHEAD M: New approaches to the rapid diagnosis of tuberculosis:

editorial, 264WOODMAN K see BREMNER P et alWOODMANSEY P A et al: The calcium antagonist amlodipine preferen-

tially inhibits the contraction of isolated rat pulmonary resistancearteries, 892P

WRAGG S et al: Sustained maximum voluntary ventilation causesdiaphragm fatigue, 858P

WRIGHT J see POWNEY J et al

xXAUBET A see AGUSTI C et al

ROCA J et al

yYACOUB M see ALTON EW FW et alYAMAGUCHI M, NISHIYA H, MANO K, KUNII 0, MIYASHITA H:

Chronic necrotising pulmonary aspergillosis caused by Aspergillus nigerin a mildly immunocompromised host: short report, 570

YAMAMOTO M see NISHIMURA M et alYAMASHITAY, NAKAGOMI K,TAKEDAT, HASEGAWA S, MITSUI

Y: Effect of heparin on pulmonary fibroblasts and vascular cells, 634YANG P-CCHANG D-B, LEE Y-C, YU C-J, KUO S-H, LUH K-T: Mediastinal

malignancy: ultrasound guided biopsy through the supraclavicularapproach, 377

CHANG D-B,YU C-J, LEE Y-C, KUO S-H, LUH K-T: Ultrasoundguided percutaneous cutting biopsy for the diagnosis of pulmonaryconsolidations of unknown aetiology, 457

YATES D H et al: Evaluating 99mTc DTPA lung clearance: how variableare results? 888PPassive smoking does not change lung permeability acutely, 860P

YATES DW see DU PELOUX MENAGE H et alYENER A see ERSOZ A et alYERNAULT J C see LEDUC D et al

NOSEDA A et alYOSHIOKA A see NISHIMURA M et alYU C-J seeYANG P-C et alYUKSEL B, GREENOUGH A: Randomised trial of inhaled steroids inpreterm infants with respiratory symptoms at follow up, 910

zZACH M S, OBERWALDNER B: Effect of positive expiratory pressure

breathing in patients with cystic fibrosis: correspondence, 66ZALACAIN R see SOBRADILLO V et alZHAO L et al: Resolution ofpulmonary hypertension, pulmonary vascular

remodelling and right ventricular hypertrophy induced by seven dayhypoxia in rats, 227PVascular reactivity to brain natriuretic peptide in the isolated and blood

perfused rat lung, 226PZONTA S see ZUCCONI M et alZUCCONI M, FERINI-STRAMBI L, PALAZZI S, ORENA C, ZONTA

S, SMIRNE S: Habitual snoring with and without obstructive sleepapnoea: the importance of cephalometric variables, 157

ZWINDERMAN A H see NIEROP G et al

1103

Thorax 1992;47:1 104-1116

VOLUME 47: INDEX TO TITLES

AAA amyloidosis, causing diffuse interstitial lung disease: short report,

323Abdominal surgery

elective, value of physiotherapy before, 249Ppostoperative chest infection, not influenced by salbutamol, 249P

Acculevel compared with HPLC for plasma theophylline estimation,255P

Acetazolamide, does not inhibit cough responses to chloride deficientchallenge, 234P

Achilles tendon rupture, underrated complication of corticosteroidtreatment: correspondence, 484

Actinomycosis, endobronchial, mimicking pulmonary neoplasm: shortreport, 664

Adenocarcinomaarising in mucinous cystadenoma of the lung: short report, 129primary pulmonary, and alveolar atypical hyperplasia, clinicopatho-

logical study of 10 cases, 1041Adenosine 5'-monophosphate, with inhaled loop diuretics, in asthma,

time course of change in bronchial reactivity, 872PAdrenaline

intravenous, in normal, atopic and asthmatic man, bronchial responsive-ness, 256P

and salbutamol, comparison of bronchodilator potencies and effects onbronchial reactivity in mild asthmatic subjects in vivo, 874P

Adult respiratory distress syndrome, 651endotoxin, antiendotoxin core antibodies, and oxygen requirement,245P

future treatment, cellular mechanisms: editorial, 260: correspondence,668

initial experience of artificial surfactant therapy, 243Pneutrophil elastase levels and oxygen requirement, 245P

Aeromonas hydrophila fulminant pneumonia, in a fit young man: shortreport, 482

Aerosol inhalers, orifice size, respirable fraction and clinical response inrelation to, 239P

Africa, rural, pulmonary disease statistics, 228PAgeand height adjustment for cross sectional studies of lung function,

children, 6-11 years, 707relation to serum elastin peptide concentration, working men, 937

AIDSantiretroviral treatment modifies phenotype of alveolar macrophages,223P

and bronchopulmonary Kaposi's sarcoma, 721, 726diagnostic value of 99mTc DTPA clearance: correspondence, 138and the lung: update 1992, 305, 381multinucleated cells in bronchoalveolar lavage, 240Prelated primary intrathoracic lymphoma, 223PRhodococcus equi causing endobronchial mass with lung abscess: short

report, 62and tuberculosis, is the "white plague" up and coming? 223Psee also HIV

Air transport and fate of pneumothorax in pleural adhesions: short report,833

Airflow limitationchronic

cognitive functioning, pulmonary physiology, and quality of life,865P

interrelations among physiological and psychological function, 850Prespiratory muscle training, controlled trial, 598weightlifting exercise, 70severe, walking tests, 211P

Airflow obstructionand breath sounds, during asthma exacerbations, relation between,888P

bronchial carcinoma, and breathlessness, 862Pvalidity of peak expiratory flow measurement in assessing reversibility,

162Airway calibre as confounder in interpreting bronchial responsiveness in

asthma, 702Airway distensibility, in asthma, evaluation, 849PAirway hyperreactivity to methacholine, 885PAirway inflammation

allergen evoked, asthma, imaging, 870Pasthma, induced sputum cell counts, 25

Airway microvasculature and exercise induced asthma: occasionalreview, 748

Airway resistance, dependence during interruption on rate of change offlow before interruption, 862P

Airway responsiveness, asthmatic symptoms, and appreciation ofbronchoconstriction, 846P

Airway smooth muscleCa2+ store during sustained agonist activation, 213Pcells, beta-adrenoceptor desensitisation control, 212P

Airways disease, eicosanoid production by leucocytes, 242PAlcohol, relation to serum elastin peptide concentration, working men,

937Aldosterone, secretion, effects of acute and chronic hypoxia, 846PAlginate, in infection with mucoid Pseudomonas aeruginosa in cystic

fibrosis, 6Allergen

challenge, effect of local hyperthermia, 232Pevoked bronchoconstriction, inhalation effect of leukotriene D4 recep-

tor antagonist ICI 204,219, 871Pinduced asthma, adhesion molecules, ICAM- 1, E-selectin andVCAM-

1 expression, 852Peffects of budesonide and terbutaline, 231Prepeatability of early response, 231P

induced contractions of passively sensitised human bronchi in vitro,effect of frusemide, 872P

induced release of inflammatory mediators into nasal lavage fluid andeffect of topical glucocorticoids, 231P

inhalation challengeCD4 + T cells, IL-4, 5 and GM-CSF mRNA in bronchoalveolar

lavage after, 852Pand increases in activated T lymphocytes, eosinophils, and cytokinemRNA expression for IL-5 and GM-CSF in bronchial biopsies,852P

Allergic rhinitiseffect of local hyperthermia, 232Phistamine challenge, 231Pinfiltration by lymphocytes in nasal mucous membrane, 232Pinflammatory mediators in nasal lavage fluid, 231Pleucocyte endothelial adhesion molecules, expression increased, 232Pstudy of nasal mucosa: editorial, 993

Alphal antitrypsin deficiencyin emphysema, prevalence in patients referred for lung transplantation,248P

somatic gene therapy, recent advances, 315Alternative and complementary medicine for asthma: correspondence,

762Aluminium potroom asthma, diagnosis, peak expiratory flow and

responsiveness to methacholine, 292Alveolar atypical hyperplasia, and primary pulmonary adenocarci-noma, clinicopathological study of 10 cases, 1041

Alveolar-capillary barrier, and alveolar surfactant system, integrity,smokers, 603

Alveolar macrophageaccessory cell function correlates with bronchoalveolar lavage lympho-

cytosis in asthma, 873Pnumbers in current smokers and non-smokers, 437

Ambulatory oxygen treatment, effect on symptoms and exercisecapacity in chronic heart failure, 858P

Amilorideeffect on airway response to metabisulphite in asthma, 872Pnebulised, in cystic fibrosis, 867Psensitive transport, inhibition by 5HT in airway epithelia, 233P

Aminophylline, effect on brain tissue oxygenation in chronic obstructivelung disease, 1025

Amiodarone, pulmonary complications after long term treatment, 372Amlodipine, inhibition of pulmonary resistance arteries, 892PAmmonia inhalation, acute and long term respiratory damage following:

short report, 755Amosite asbestos, long fibres, and tumour necrosis factor, and opsonisa-

tion with IgG, 214PAmylase isoenzyme, analysis in differential diagnosis of amylase rich

pleural effusions, 887PAnti-inflammatory drugs increase mRNA of growth factor platelet

derived growth factor-B in alveolar macrophages, 893PAnti-tuberculous therapy in the elderly, side effects, 875PAntibiotic treatment in pneumonia due to Q fever, 276Antigens, of lung cancer: new perspectives in lung cancer, 53Antiretroviral treatment modifies phenotype of alveolar macrophages

in AIDS, 223PArachidonic acid metabolism by human bronchial epithelial cells,243P

Artificial surfactant therapy, in ARDS, initial experience, 243PArytenoid region, abnormal movement as cause of upper airway

obstruction: short report, 840

1104

Index to titles

Asbestosis, high resolution computed tomographic assessment, 645Aspergilloma, pulmonary, treatment with itraconazole: correspondence,

328Aspergillosisbronchopulmonary

chronic allergic, and asthmatic patients skin test positive to A.fumigatus, computed tomography of the lungs, 854P

progressiveness, 854Pinvasive

complicated by subclavian artery occlusion and costal osteomyelitisafter autologous bone marrow transplantation: short report, 136

with idiopathic thrombocytopenic purpura without underlying lungdisease: correspondence, 328

Aspergillusffumigatus, specific IgG antibody, and precipitins, chest unitpopulation, 48

Aspergillus niger causing chronic necrotising pulmonary aspergillosis ina mildly immunocompromised host: short report, 570

Aspirin intolerance, asthmatic patients with and without, plateletkinetics, 533

Asthmaacute

can admission rates be reduced, 239Pdischarge and follow up, 209Pmanagement, audit after feedback and guidelines, 861Poxygen saturation changes after nebulised salbutamol, 220Ppeak inspiratory flow rates, are they adequate for efficient use of a

Turbohaler?, 239Pprednisolone, "abruptly stopping" compared with "tailing off",228P

steroid tapering, 845Pacute severe

corticosteroid effects: editorial, 582corticosteroids, effectiveness of low doses, 584sensor motor impairment following prolonged ventilation with

isoflurane and vecuronium, reversible: short report, 1078serum cytokines and salivary platelet aggregation factor, 870P

airway calibre as confounder in interpreting bronchial responsiveness,702

airway distensibility, evaluation, 849Pairway inflammation, induced sputum cell counts, 25alternative and complementary medicine: correspondence, 762and beta agonists, state of the art, report on Royal Society of Medicine

seminar, 568and bradykinin: occasional review, 979bradykinin responsiveness and refractoriness, factors determining,856P

breath sounds, effect of methacholine induced bronchoconstriction on

spectral characteristics, 680Bricanyl Turbohaler and pressurised meter dose inhaler compared,238P

brittleHPLC measurement of plasma terbutaline, 884Pinfused terbutaline with and without oral terbutaline, side effects,256P

psychosocial factors, 209PBRL38227 and salbutamol compared, 254Pbronchial, effect of dietary sodium on severity, 360bronchial responsiveness to intravenous adrenaline, 256Pcare

integrated, general practice, 238Ptargetting in general practice, 238P

caused by western red cedar, sensitisation to plicatic acid, 214Pchildren, spontaneous recovery after histamine challenge, bronchodila-

tation assessment, 355chronic, ultrasonographic evaluation and strength assessment of respira-

tory and thigh muscles, 849Pcirculating adhesion molecules, 852Pclinic, nurse run

assessment, 238Ppaediatric department, evaluation, 221P

deathsand prescribed fenoterol, New Zealand, 1981-7: correspondence, 400and salbutamol, New Zealand, 1969-76, case-control study, 210P

disruption site of bronchial epithelium, 499drug and peak flow meter prescribing, PACT data analysis, 884Peffect of ipratropium bromide on posture induced changes of expiratory

flow indices, 253Peffect of lipoxin A4 on airway responses, 242Peffect of low sodium diet, general practice, 256Pand employment, young adults, 19epidemics, Barcelona, clinical aspects and intriguing findings, 197:

correspondence, 668, 843, 1086evaluation of impairment of health related quality of life, questionnaire,

76exacerbations, breath sounds and airflow obstruction, relation between,888P

and exercise, suitable case for rehabilitation: editorial, 765

exercise inducedairway microvasculature: occasional review, 748attenuation by local hyperthermia, 592chronic dosing with inhaled salmeterol, 255Pnedocromil sodium aerosol and dry powder compared, 230Pand sodium meta-bisulphite, cross refractoriness between, 873Purinary leukotriene E4 excretion, 241P

fluticasone propionate and budesonide compared in adult patients,891P

from birth to age 23, incidence and relation to prior and concurrentatopic disease, 537

and gastro-oesophageal reflux, pH measurements, 881Pin general practice, prevalence and treatment, 846Pand general practitioners: editorial, 669GPs' referral, 238Phospital management, improving, where next? 845PIg replacement therapy, 254Pimaging allergen evoked airway inflammation, 870Pinduced sputum as method of assessing airway inflammation, 212Pinhaled corticosteroids, benefits and risks: editorial, 404: correspondence,

1084like symptoms, self management, Scottish community, 890Pmanagement

audit, 884Paudit of patient education, 239Pbefore hospital admission, audit, 884P

markers of severity and death, 209Pmeasures of severity and response to treatment, relation to outcome in

acute severe asthma, 943mild, caffeine decreases histamine induced bronchoconstriction, 889Pmild atopic

effect of budesonide and terbutaline on bronchial reactivity toallergen, 231P

repeatability of early response to allergen, 231Pmortality, five year review, 209Pnedocromil sodium inhibits histamine release, 212Pnew drug, clinical trial, recruitment difficulties, 254Pnocturnal symptoms, morning symptoms, and night time inhaler use,861P

nocturnal, terfenadine, 230Poccupational

induced by tetrachloroisophthalonitrile: short report, 760respiratory symptom, spirometry, and employment status follow up,229P

paper wrapper's, polyethylene shrink wrapping causing: short report,759

pet ownership and associated morbidity, 210Ppolicy in schools, Great Britain, 237Ppolicy in state schools of 14 education authorities, UK, 890Ppoorly perceived: editorial, 408prevalence, Asian and European children in Southampton compared,

529repeatability of cell counts in BAL fluid, 241Prole of NANC system in overnight variation of airway calibre, 243Pscreening, British army, 890seasonal effects of dietary fish oil supplementation, 885Pself management plan, "credit card," Maori community, 890Pself reported, and respiratory symptoms, prevalence, student popula-

tion, 209Psevere acute, intravenous corticosteroids, controlled trial, 588stable, serum cytokines and salivary platelet aggregation factor, 870Psteroid dependent

auranofin treatment, 349: correspondence, 992methotrexate, long term results, 254P

ten year follow up, 180 adults, factors determining outcome, 14:correspondence, 484

Web 2086 has no steroid sparing effect, 871Pwith and without aspirin intolerance, platelet kinetics, 533

Asthmatic airways, and subepithelial fibrosis, 854PAsthmatic symptoms, airway responsiveness, and appreciation of

bronchoconstriction, 846PAtopic disease, prior and concurrent, and asthma from birth to age 23,

incidence and relation, 537Atopyand restriction of peripheral T cell receptor Va gene, 853Pas risk factor for cryptogenic fibrosing alveolitis, 849P

Atrial natriuretic peptideinfused, high dose, bronchodilator and cardiovascular response, 256Pinhibition of hypoxic vasoconstriction, 892Prelaxes resistance vessels at pathophysiological concentrations, 225Prelease in sleep apnoea hypopnoea syndrome, 235P

Auditof acute asthma management, 861Pof asthma management, 884P

before hospital admission, 884Pof clinical investigation of pleural effusion, 734computerised bronchoscopy reports, 888P

1105

Index to titles

criterion based, of community acquired pneumonia, 874Pof inhaler technique in patients and hospital staff, 237Plung function laboratories, West Midlands initiative, 848Pof management of spontaneous pneumothoraces, 887Pof patient education in asthma management, 239Pof pleural biopsies, argument for setting up pleural biopsy service,849P

of prolixity, investigation rates and follow up rates, in 490 newconsultations in a chest clinic, 881P

Auranofin, in steroid dependent asthma, 349: correspondence, 992Avian antigen concentration, effect of ventilation, animal laboratory,889P

Azlocillin, nebulised, to prevent resistant pseudomonas in long termtreatment with ciprofloxacillin, 251P

Aztreonam, and ceftazidine, intravenous, compared, in treatment ofrespiratory exacerbations in cystic fibrosis, 867P

BB lymphocyte accumulations in human pulmonary sarcoidosis, 964Balloon valvuloplasty, surgical closed pulmonary valvotomy as back up

in critical pulmonary stenosis, 179Barcelona, asthma epidemics, clinical aspects and intriguing findings,

197: correspondence, 668, 843, 1086Basal metabolic rate in obstructive sleep apnoea, 878PBCG vaccinated M tuberculosis infection, and generation of cytolytic T

cells, 695BCNU related pulmonary fibrosis, free radical activity serum concentra-

tions, 219PBeclomethasone dipropionateand budesonide compared, inhaled, high dose, 845Pinhaled, high dose, and intermittent systemic corticosteroids, and bone

density, asthmatic patients, 414Beh4et's syndrome, life threatening chylous pleural and pericardial

effusion: short report, 64Beta adrenergic receptor density, asthmatic subjects on cortico-

steroids, 871PBeta adrenoceptor desensitisation, control in airway smooth muscle

cells, 2121PBeta agonists in asthma, state of the art, report on Royal Society ofMedicine seminar, 568

Beta receptor agonism, partial v full, clinical study of inhaledsalbutamol and fenoterol, 882P

Bioelectric properties of cystic fibrosis airways obtained at heart-lungtransplantation, 1010

Bisphosphonates, oral and intravenous compared, osteoporosis, cortico-steroids, and bone disease, 854P

Blood pressure, night time, in obstructive sleep apnoea, snoring, andnormal sleep, 216P

Body composition, and exercise performance, in chronic obstructivepulmonary disease: correspondence, 66

Bodybuilders with large necks, do they have obstructive sleep apnoea?,879P

Bone density, asthmatic patients taking high dose inhaled beclometha-sone dipropionate and intermittent systemic corticosteroids, 414

Bone disease, osteoporosis, and corticosteroids, oral and intravenousbisphosphonates compared, 854P

Bone marrow transplantationautologous, invasive aspergillosis complicated by subclavian artery

occlusion and costal osteomyelitis: short report, 136lung function measurements to predict risk of pneumonitis after, 421

Bone mineral density changes, in women taking inhaled corticosteroids,228P

Bone turnover during short course prednisolone treatment in patientswith chronic obstructive airways disease, 418: correspondence, 1084

Bovine tracheal smooth muscle, presence of multiple phosphoinositi-dase isoforms, 213P

Bradykininantagonist (HOE 140), evaluation against bradykinin and platelet

activating factor induced airway responses, 241Pand asthma: occasional review, 979and [desArg9]-bradykinin, inhaled, modulation of tracheobronchial

clearance, normal subjects, 860Pand histamine

and cholinergic pathways, nasal responses, 894Pcomparative nasal effects, 232Pnasal challenge, changes in mucosal blood flow and airways resistance

after, 894Pand hypertonic saline challenges in asthma, cross refractoriness

between, 873Pinduced nasal symptoms and plasma leakage, repeatability and reversi-

bility, 232Pinhaled, acute effect on tracheobronchial clearance in normal humans,

952responsiveness and refractoriness in asthma, factors determining,856P

Brainpreoperative computed tomography in non-small cell bronchogenic

carcinoma, 106tissue oxygen tension, effect of aminophylline, 1025

Brain natriuretic peptide, vascular reactivity to, 226PBranhamella catarrhalis organisms in presence and absence of

respiratory tract infection, differences in adherence, 252PBreath holding time, in normal subjects, snorers, and sleep apnoea,880P

Breath soundsand airflow obstruction during asthma exacerbations, relation between,888P

in asthma, effect of methacholine induced bronchoconstriction on

spectral characteristics, 680Breathing strategy, effect on two techniques of incremental threshold

loading, 880PBreathlessness

bronchial carcinoma, and airflow obstruction, 862Phypoxaemia, and survival, community study, 847Pand shoulder pain, 216P

Bricanyl Turbohaler and pressurised meter dose inhaler compared, in

adult asthmatics, 238PBritish Thoracic Society, survey of respiratory function laboratories and

technicians, 848PBRL38227 and salbutamol compared, in asthma, 254PBronchial atresia, congenital, with regional emphysema associated with

pectus excavatum: short report, 1082Bronchial biopsy samples, quantitative morphology and water distribu-

tion, 504Bronchial carcinoma

airflow obstruction, and breathlessness, 862Peffects of endobronchial radiotherapy, 250P

Bronchial compression, as result of lung herniation after pneumonec-tomy: correspondence, 208

Bronchial epithelium, disruption site in asthmatic and non-asthmaticsubjects, 499

Bronchial hyperresponsiveness, airway calibre, and atrial natriureticpeptide, in chronic heart failure, 881P

Bronchial irritability, in non-asthmatic CAO, significance of symptoms,865P

Bronchial mucosal blood flow, changes after lung transplantation,877P

Bronchial reactivityeffects of six week course of salmeterol, 230Psevere unstable and milder stable asthma compared, 855P

Bronchiectasisclinically stable, sputum sol phase proteins and elastase activity, 88experimental

effects of corticosteroids, 894Pproducing potential of bacteria from purulent sputum, 859P

nebulised IgG as adjunctive therapy, 894Popportunistic mycobacteria infection, 251P

Bronchiolitis organising pneumonia, obliterative, and cryptogenicorganising pneumonitis (BOOP and COP): corresponidence, 207

Bronchitis, chronic, effects of N-formyl-methionyl-leucyl-phenylalanineinhalation, 279

Bronchoalveolar lavageCD4+ T cells, IL-4, 5 and GM-CSF mRN.A after allergen inhalation

challenge, 852Pfluid, endotoxin assay in rapid diagnosis of Gram negative pneumonia,

547how much fluid stays in lung after, 887Plymphocytosis in asthma, and alveolar macrophage accessory cell

function, 873Pas research tool: correspondence, 207

Bronchocentric granulomatosis, associated with pure red cell aplasiaand lymphadenopathy: short report, 131

Bronchoconstrictionasthmatic symptoms and airway responsiveness, 846Pmethacholine induced

and dose-response relation of nebulised salbutamol, 873Peffect on spectral characteristics of breath sounds in asthma, 680

paradoxical, associated with salmeterol metered dose inhaler, 254Pprovoked by methacholine, reduced subjective awareness, elderly, 410

Bronchodilatation, after spontaneous recovery from histamine chal-lenge, asthmatic children, 355

Bronchodilator response, interpretation, in obstructive airways disease,429

Bronchogenic carcinomaresectable, and severe coronary artery disease, preoperative laser

therapy: short report, 1075sputum induction in cytological diagnosis, 887P

Bronchogenic cyst, mediastinal, and recurrent respiratory obstruction:short report, 660

Bronchography, complementing fibreoptic bronchoscopic to evaluatesolitary pulmonary nodule, 886P

1106

Index to titles

Bronchopulmonary aspergillosis, see Aspergillosis, bronchopulmo-nary

Bronchopulmonary Kaposi's sarcoma, in AIDS, 721, 726Bronchoscopy, computerised reports and audit, 888PBronchus associated lymphoid tissueand airway immunopathology in smokers, 886Pdoes it exist in humans, 241P

Budesonideand beclomethasone dipropionate compared, inhaled, high dose,845P

and terbutaline, effects on bronchial reactivity to allergen in mild atopicasthma, 231P

Byssinosis, a form of occupational asthma: editorial, 401

C1lC-S-CGP 12177, for in vivo quantification of pulmonary beta-

adrenoceptor density, 853PCachexia, in cystic fibrosis, TNF-alpha and resting energy expenditure,868P

Caesium-137, for medium dose rate endobronchial radiotherapy: newtechniques, 474

Caffeine decreases histamine induced bronchoconstriction in mildasthma, 889P

Calcification, localised pulmonary metastatic, associated with pulmonaryartery obstruction, 174

Calcium2" store during sustained agonist activation, airway smoothmuscle, 213P

Capsaicin, inhaled, cough receptor sensitivity to, effects of methacholineinduced bronchoconstriction and procaterol induced bronchodilation,441

Carbohydrate metabolism, obstructive sleep apnoea, and CPAP, 235PCarbohydrate rich versus fat rich loads, effect on gas exchange and

walking performance in chronic obstructive lung disease, 451Carbon dioxide

influence of mechanical limitation on responses to, 211Ptension

alveolar, during tidal breathing, new and simple technique forestimating, 210P

transcutaneous, gas exchange during exercise, 848PCarbon monoxide

gas transfer, relation to microscopic and macroscopic emphysemameasurements, 144

transfer factor, gas mixtures for estimating, 862Psingle breath, in never smokers, 167

Carbonic anhydrase inhibitor, attenuates sodium metabisulphiteinduced bronchoconstriction, 234P

Carboplatin, etoposide and epirubicin combined, in small cell lungcancer relapse, 369: correspondence, 668

Cardiopulmonary bypassand lung injury, pilot study of infused pentoxifylline in model of ARDS,244P

porcine, model of acute lung injury with increased pulmonary endothe-lial permeability, 244P

Carinal transplantation, 968CD4 blood lymphocyte numbers, in community acquired pneumonia,253P

CD4 counts, higher than average, in HIV infected patients, and severecytomegalovirus pneumonitis, 301

CD8 blood lymphocyte numbers, in community acquired pneumonia,253P

Ceftazidine, and aztreonam, intravenous, compared, in treatment ofrespiratory exacerbations in cystic fibrosis, 867P

Cell behaviour, fine tuning by modulation of plasma membranereceptors, 563

Cephalometric variables, and habitual snoring with and withoutobstructive sleep apnoea, 157

Cephalometry, in airway assessment, obstructive sleep apnoea, 150Chemiluminescence responses of alveolar macrophages obtained from

each lung in patients with lung cancer, 250PChest clinic, audit, Edinburgh, 881PChest drain insertion, expansible cannula, new technique: technical note,657

Chest drainage systems, randomised clinical trial, 461: correspondence,1086

Chest x ray films, pre-employment, for health service staff, who needsthem, 877P

Children and smoking, the problem and the way forward: editorial, 485Chlamydia pneumoniae serology inUK populations, 218PChloride

current, second messenger regulation, human airway epithelium,860Pin sodium absorbing epithelium, 233P

deficient challenge, cough responses, not inhibited by acetazolamide,234P

transport, active, in tracheal epithelium, regulated by prostaglandins,233P

Chlorine gassing, pulmonary sequelae, 236PCholinergic pathways in AMP and sodium metabisulphite induced

bronchoconstriction in asthma, 213PChronic airflow obstruction

effect of beclomethasone dipropionate and prednisolone treatment onhypothalamic-pituitary-adrenal function, 229P

non-asthmatic, bronchial irritability, significance of symptoms, 865PPEF, FEV1 reversibility, and bronchial responsiveness, 865P

Chronic airways obstruction, development of shuttle walking test ofdisability, 1019

Chronic heart failure, diaphragmatic strength, 216PChronic obstructive airways disease, short course prednisolone

treatment, bone turnover during, 418: correspondence, 1084Chronic obstructive lung disease

corticosteroid effects on bronchodilator action, 616domiciliary ventilation: editorial, 334

effects on sleep and quality of life, 342dyspnoea assessed by visual analogue scale during progressive and high

intensity exercise, 363effect of aminophylline on brain tissue oxygenation, 1025effect of carbohydrate versus fat rich loads on gas exchange and walking

performance, 451negative pressure ventilation, and sleep apnoea induction, 612nutritional support: editorial, 141regional structure-function correlations measured with positron emis-

sion tomography, 914Chronic obstructive pulmonary disease

basal metabolic rate, weight loss, and decline in FEV1, 847Pbody composition and exercise performance: correspondence, 66bronchodilator reversibility to low and high doses of terbutaline and

ipratropium, 255Peffect of oxitropium bromide and salbutamol, 211Phypoxia and sodium retention, 847Phypoxia and water retention, 846Pnew method for determining oxygen uptake kinetics, 210Ppredictors of symptomatic and functional benefit after oxitropium,865P

severe, effects on intravenous prostacyclin, 893PChronic renal failure, pulmonary function, effects of dialysis and

transplantation: correspondence, 763Chylothorax, as complication of oesophageal sclerotherapy: short report,

134Chylous pleural and pericardial effusion, in Behiet's syndrome: short

report, 64Cigarette smoke condensate, effect on epithelial cell permeability,245P

Cilary beat frequency, non-typable Haemophilus influenzae culturefiltrates slow, 868P

Ciliary beating, Pseudomonas aeruginosa pyocyanin slows via cyclic AMPdependent mechanism, 869P

CiLiary ultrastructure, mucociliary function, and ciliary orientation, inYoung's syndrome, 184

Clonidine, effect on sensory nerve mediated cough, guinea pigs andhumans, 870P

Cocaine induced eosinophilic lung disease: short report, 478Collagen vascular disease, interstitial pulmonary fibrosis with and

without, two year follow up, 1035Colophonyimmune responses to, agent causing occupational asthma, 1050toxic effect to lung epithelial cells contrasts with lack of effect on lung in

vivo, 214PCommunity acquired pneumonia: editorial, 329Complementary medicine for asthma: correspondence, 762Computed tomography

in airway assessment, obstructive sleep apnoea, 150brain, preoperative, in non-small cell bronchogenic carcinoma, 106in detection and quantification of pulmonary emphysema: editorial,

1001Continuous positive airways pressure

nasal, controlled trial in heart failure with sleep disordered breathing,216P

and obstructive sleep apnoealipid and carbohydrate metabolism, 235Pmetabolic hormones, 235P

Cor pulmonale, clinicopathological correlations, 494Coronary artery disease, severe, and resectable bronchogenic carci-noma, preoperative laser therapy: short report, 1075

Correction, 139, 738Corticosteroid dependent lung disease, and osteoporosis, intravenous

pamidronate, 932Corticosteroids

Achilles tendon rupture an underrated complication: correspondence,484

in acute severe asthma, effectiveness of low doses, 584effects in acute severe asthma: editorial, 582effects on bronchodilator action in chronic obstructive lung disease,616

1107

Index to titles

effects on experimental bronchiectasis, 894Pinhaled

benefits and risks: editorial, 404: correspondence, 1084bone mineral density changes in women taking, 228P

inhaling by different devices, difference in systemic absorption, 891Pintravenous, in severe acute asthma, controlled trial, 588osteoporosis, and bone disease, oral and intravenous bisphosphonates

compared, 854Psystemic, intermittent, and high dose inhaled beclomethasone dipropio-

nate, and bone density, asthmatic patients, 414see also Steroid(s)

Corynebacterium pseudodiphtheriticum pneumonitis, in a leu-kaemic child: short report, 838

Cost of care, cystic fibrosis: editorial, 673; paper, 684Cough receptor sensitivity to inhaled capsaicin and tartaric acid, effects

of methacholine induced bronchoconstriction and procaterol inducedbronchodilation, 441

Cough reflex5-HT mechanisms influence control, guineapig, 234Psensitivity, and 5-HT, 895P

Cough responses to chloride deficient challenge, not inhibited byacetazolamide, 234P

Critical care, and the pulmonary physician, 463, 465, 555, 651, 743, 825,971

Cryptogenic fibrosing alveolitisapposition of fibroblasts to mast cells and lymphocytes, 219Patopy as risk factor, 849Pcirculating free radical activity, 219Phigh resolution computed tomographic assessment, 645ventilation perfusion scans, 881P

Cyclic GMP, urinary, in obstructive sleep apnoea, 878PCyclooxygenase inhibition modulates change in bronchial reactivity to

methacholine with inhaled frusemide in normal subjects, 853PCyclosporin A, and dexamethasone, effects onT lymphocytes in vitro in

chronic severe asthma, 873PCysteine levels in bronchoalveolar lavage and lung tissue, effect of high

dose N-acetylcysteine, 246PCystic fibrosis

in a 70 year old woman: short report, 202acute severe deterioration associated with influenza A virus infection,

112addition of exercise to physiotherapy, effect on sputum expectorationand lung function, 867P

adults, serum IgG antibodies to P cepacia, 252Pairflow obstruction, TNF-alpha and leukotrienes, 868Pairway epithelial chloride channel which functions normally, 868Pairways, obtained at heart-lung transplantation, bioelectric properties,

1010antibiotic prescribing practices, UK and Ireland, 252Pcachexia, TNF-alpha and resting energy expenditure, 868Pchronic supplemental enteral nutrition via nasogastric route, 866Pcomparison of clinical features in patients with different genotypes,

866Pcost of care: editorial, 673; paper, 684current survival and population estimates to the year 2000: correspond-

ence, 327, 400effect of positive expiratory pressure breathing: correspondence, 66and emphysema, comparison of six minute walk test performance,862P

end stage respiratory disease, heart-lung transplantation, 248Pextrapulmonary sites of P aeruginosa, adults, 426Flutter VRPI device, evaluation in young adults, 237Pglutathione state in adults, 866Pincreased incidence of Pseudomonas cepacia infection in adult centre,

866Pinfection with mucoid Pseudomonas aeruginosa, role of alginate, 6lung disease, role of viral infections: editorial, 69nebulised amiloride trial, 867PP aeruginosa infection, seasonal onset, 109predictors of survival of patients awaiting hear-lung transplantation,and assessment of postoperative survival, 247P

related diabetes mellitus, prevalence and insulin responses in adults,866P

respiratory exacerbations, intravenous ceftazidine and aztreonam com-

pared, 867Psomatic gene therapy, recent advances, 315vitamin A and E concentrations, 867P

Cytochrome C and S pneumoniae interference with oxidative response ofneutrophils, 869P

Cytokinesimmunoreactivity, in normal human nasal mucosa, 896Pserum, in acute severe asthma, acute myocardial infarction, and stable

asthma,870PCytolytic T cells, generation in M tuberculosis infection and vaccinated

with BCG, 695

Cytomegalovirus pneumonitis, severe, in HIV infected patients withhigher than average CD4 counts, 301

Cytoskeletal peptides, expression in resected non-small cell lung cancer,249P

DDeep vein thrombosis, and/or pulmonary embolism, four weeks' versus

three months' anticoagulation, 217PDefensins, ancient but potentially dangerous weapons in the armoury,

195Der pl levels six months after treatment of houses with liquid nitrogen,219P

Desmoid tumours, treatment, in Gardner's syndrome: short report, 662Dexamethasoneand cyclosporin A, effects on T lymphocytes in vitro in chronic severe

asthma, 873Ptreatment, effect on TNF in bronchoalveolar secretions in respiratory

distress syndrome, infants, 44Diabetes mellitus, and cystic fibrosis, prevalence and insulin responses

in adults, 866PDialysis, and pulmonary function in chronic renal failure: correspondence,

763Diaphragm fatigue

caused by sustained maximum voluntary ventilation, 858Pand hypercapnia, in patients with a thoracoplasty, 880P

Diaphragmatic paralysis, bilateral, neck osteopathy causing: shortreport, 201

Diaphragmatic strength in chronic heart failure, 216PDiaphragmatic thickness-respiratory muscle strength relation-

ship, evaluation by ultrasound, 215PDiathermy resection, bronchoscopic, for tracheobronchial obstruction,886P

Diffuse interstitial lung disease, due to AA amyloidosis: short report,323

Digitalisation, prophylactic, in pulmonary surgery, 41Diskhalers, determinants of inspiratory flow rate, 239PDNA

amplification for P carinii from saline mouth rinse, 857Pmycobacterial

amplification, IS611O and 65kDa antigen gene compared, tuberculo-sis diagnosis, 690

detection in tuberculous pleurisy by polymerase chain reaction, 265Domiciliary oxygen treatment, East Anglian GP survey, 864PDomiciliary ventilation in chronic obstructive lung disease: editorial,

334effects on sleep and quality of life, 342

Donor lung lavage, value in identification of postoperative infectionfollowing lung transplantation, 248P

Dopaminergic stimulation, effects on airway dynamics and respiratorymuscle strength in Parkinson's disease, 880P

Doxapram, v nasal ventilation, in treatment of type II respiratory failurecomplicating chronic airflow obstruction, 858P

Drug delivery to lung, controlled, use of liposomes: editorial, 257Dyspnoea, assessed by visual analogue scale, in chronic obstructive lung

disease during progressive and high intensity exercise, 363

EEicosanoid production by leucocytes in airways disease, 242PEicosapentaenoic acid, exogenous, effects on in vitro eosinophil

generation of leukotriene C, 241PElastase

activity, and sputum sol phase proteins, in clinically stable bronchiecta-sis, 88

inhibitors, effects on extracellular proteolysis by neutrophils, 246PElastin peptide, serum concentration, relation to age, FEV,, smoking

habits, alcohol consumption, and protease inhibitor phenotype, workingmen, 937

Emphysemaand cystic fibrosis, comparison of six minute walk test performance,862P

measurements, microscopic and macroscopic, relation to carbon mon-oxide gas transfer, 144

and normal subjects at standardised airflows, lung sound intensity,674

and single lung transplantationa, antitrypsin deficiency, 248Pventilation-perfusion relationships, 248P

Empyemaclinical course, 851Ppleural, microbiology, 850Ptreatment, 851P

Empyema thoracis, surgical treatment, analysis of 88 cases, 1987-1991,851P

Endobronchial actinomycosis mimicking pulmonary neoplasm: shortreport, 664

Endobronchial mucormycosis lesion, removal through rigid broncho-scope: short report, 203

1108

Index to titles

Endobronchial obstruction, malignant, endoscopic photodynamictherapy, 251P

Endobronchial radiotherapy, medium dose rate, with caesium-137:new techniques, 474

Endobronchial sonography, feasibility and preliminary results: newtechniques, 565

Endoscopic Nd YAG laser treatment for obstructive tracheal lesions,250P

Endoscopic photodynamic therapy for malignant endobronchialobstruction, 251P

Endoscopy assisted microthoracotomy: editorial, 489; 850Pinitial experience, 490

Endotoxin in bronchoalveolar lavage fluid, assay in rapid diagnosis ofGram negative pneumonia, 547

Eosinophilic lung disease, cocaine induced: short report, 478Epidermal growth factor receptor expression, and non-small cell lung

cancer survival, 860PEpithelial cells

alveolar, and liposomes, comparison of effects of oxidants, 246Ppermeability

effect of cigarette smoke condensate, 245Peffect of NO2 on TNF synthesis, 245P

Epithelial yJ5 T cells in lung infections, 253PEpithelium, tracheal, endothelin, vasopressin, and substance P like

immunoreactivity, rabbit, 1044Exerciseand asthma, suitable case for rehabilitation: editorial, 765gas exchange during, transcutaneous oxygen and carbon dioxide

tensions, 848Pinduced asthma

airway microvasculature: occasional review, 748attenuation by local hyperthermia, 592effect of mask to modify inspired air temperature and humidity, 446and inhaled frusemide, evidence of role for inhibitory prostanoids,

797performance, and body composition, in chronic obstructive pulmonary

disease: correspondence, 66and right to left shunt in pulmonary arteriovenous malformations,

790testing, incremental, two protocols compared, 210P

Expansible cannula, new technique for chest drain insertion: technicalnote, 657

Expiratory positive airway pressure, role during nasal ventilation,858P

Expiratory pressure, reduced, effect on pharyngeal size during nasalpositive airway pressure in sleep apnoea, 809

Extracellular proteolysis by neutrophils, effects of elastase inhibitors,246P

Extrinsic allergic alveolitiscaused by goose feathers in a duvet: short report, 990do interleukin-6, IgG or CD23 provide evidence for B cell activation,214P

early immune response as assessed by analysis of bronchoalveolar fluid,214P

FFat rich versus carbohydrate rich loads, effect on gas exchange and

walking performance in chronic obstructive lung disease, 451Fenestrated cup biopsy forceps, for percutaneous visceral pleuralbiopsy: technical note, 753

Fenoterolcardiovascular effects under conditions of hypoxaemia, 814and death from asthma, New Zealand, 1981-7: correspondence, 400,

574Fibroblast activation in fibrosing alveolitis, lung injury and inflamma-

tory mediators, 1064Fibroblasts, pulmonary, effect of heparin, 634Fibrosing alveolitis

associated with systemic sclerosis, high resolution computed tomog-raphy, 218P

fibroblast activation, lung injury and inflammatory mediators, 1064high resolution computed tomography assessment and 99"Tc DTPA

compared, 218Phigh resolution computed tomography correlates with BAL cell profiles,218P

Fibrosis, subepithelial, in asthmatic airways, 854PFibrotic lung disease, assessment of types I and III procollagen peptide

levels in bronchoalveolar lavage fluid and serum as markers, 219PFish oil supplements, dietary, effects on seasonal asthma in pollen

sensitive asthmatics, 885PFluoxetine, effects on sleep and breathing in obesity, 235PFluticasone propionatecompared with budesonide, in adult asthma, 891LTE4 excretion, bronchoconstriction and airway hyperreactivity after,895P

Flutter VRP1 deviceuse in post-thoracotomy patients, 236Pin young adults with cystic fibrosis, evaluation, 237P

Forced expiratory volumedecline, bronchial reactivity, smoking and atopy, 221Pdecline in CAO, 221P

Forced oscillation techniques for measuring mechanical properties ofthe respiratory system, 317

Formoterol, inhaledcomparison of cardiovascular and metabolic effects with salbutamol and

fenoterol, 882Ptime course of bronchodilating effect, 30

N-Formyl-methionyl-leucyl-phenylalanine inhalationeffects in well elderly and chronic bronchitis, 279haematological effects, 284: correspondence, 763

Free radical activitycirculating, in cryptogenic fibrosing alveolitis, 219Pserum concentrations, in BCNU related pulmonary fibrosis, 219P

Frusemideand allergen induced contractions of passively sensitised human

bronchi, evidence of role for prostaglandin E2, 895Peffect on allergen induced contractions of passively sensitised human

bronchi in vitro, 872Pinhaled, and exercise induced asthma, evidence of role for inhibitory

prostanoids, 797

GGardner's syndrome, desmoid tumours, treatment: short report, 662Gas exchangeand collateral ventilation, normal lung, 211Pduring exercise, transcutaneous oxygen and carbon dioxide tensions,848P

Gastro-oesophageal reflux and asthma, pH measurements, 881PGeneral practitioners, and asthma: editorial, 669Glucocorticoid induced peptide, and changes in neutrophil motility,

shape and adhesiveness, 860PGlucocorticoids and allergic rhinitis, 231PGlutaraldehyde, double blind inhalation challenge testing technique,889P

Glutathionelevels in bronchoalveolar lavage and lung tissue, effect of high dose

N-acetylcysteine, 246Pstate in adults with cystic fibrosis, 866P

Goose feathers in a duvet, causing extrinsic allergic alveolitis: short report,990

Gram negative pneumonia, rapid diagnosis by assay of endotoxin inbronchoalveolar lavage fluid, 547

Granulocyte macrophage colony stimulating factor expression inbronchial epithelium in asthma, 852P

Grass pollen immunotherapyeffect on cutaneous mast cell subtypes and immediate sensitivity to

allergen and histamine, 871Peffect on cytokine mRNA expression during allergen induced late

cutaneous responses, 871PGrowth factor, platelet derived growth factor-B in alveolar macrophages,

anti-inflammatory drugs increase mRNA, 893P

HHaematopoietic growth factors, and lung cancer treatment, 119Haemophilus influenzae, non-typable

culture filtrates slow ciliary beat frequency, 868Pfimbriae, adherence to HTBM and mucin glycopeptides, 252Pfimbriation of clinical isolates increases adherence, 859Pand inhibition of neutrophil locomotion, 868Pprotective effects of subminimal antibiotic concentrations, 859P

Halothane, subanaesthetic dose, and sustained hypoxia, 879PHamartomas, multiple cystic pulmonary: short report, 1076Heaf test reaction, positive, and prediction of later breakdown of

tuberculosis, Asian schoolchildren, 776Health service employees, and tuberculosis, 224PHeart failure

chronicbronchial hyperresponsiveness, airway calibre and atrial natriuretic

peptide, 881Peffect of ambulatory oxygen treatment on symptoms and exercise

capacity, 858Pwith sleep disordered breathing, controlled trial of nasal CPAP, 216P

Heart-lung transplantationin cystic fibrosis, predictors of survival in patients awaiting, 247Pcystic fibrosis airways obtained at, bioelectric properties, 1010for end stage respiratory disease in cystic fibrosis, 248Pmedium term results, 247Psteroid therapy and airway complications following, 248P

Height and age adjustment for cross sectional studies of lung function,children, 6-11 years, 707

1109

Index to titles

Helium dilution, to assess static lung volumes in healthy subjects duringocclusion of one mainstem bronchus, 848P

Heparin, effect on pulmonary fibroblasts and vascular cells, 634Hepatopulmonary syndrome, new name, old complexities: editorial,

897Hereditary respiratory diseases, somatic gene therapy, recent advan-

ces, 315High resolution computed tomography

appearances can identify labile disease in fibrosing alveolitis associatedwith systemic sclerosis, 218P

appearances correlate with bronchoalveolar lavage cell profiles infibrosing alveolitis, 218P

assessment, and 4"TC DTPA clearance, relationship in fibrosingalveolitis, 218P

Hip fracture, interaction between current smoking, leanness, andphysical inactivity in prediction, 861P

Histamineand bradykininand cholinergic pathways, nasal responses, 894Pcomparative nasal effects, 232Pnasal challenge, changes in mucosal blood flow and airways resistance

after, 894Pbronchial challenge, in symptom free textile workers, as measured by

dose response, 889Pbronchial responsiveness, relation to bronchoconstriction after inhaled

lipopolysaccharide, 288challenge in allergic rhinitis, 231Pinduced bronchoconstriction

inspiratory muscle strength and endurance during, 922in mild asthma, caffeine decreases, 889P

HIV disease, pulmonary complications, recent developments in manage-ment, 381: correspondence, 1084

HIV infectionadvanced, and persistent alveolar increased permeability to ""TcDTPA: correspondence, 575

asymptomatic, PCR detection of P carinii, 223PHIV positive patients

acute respiratory illness, investigation using indium- 111 labelled poly-clonal immunoglobulin scans, 240P

changing patterns of respiratory disease, 1986-7 and 1990-1, 854Pdiagnosis of P carinii pneumonia by simple outpatient assessments,

1005with higher than average CD4 counts, and severe cytomegalovirus

pneumonitis, 301tine testing, 877P

Horseshoe lung with left lung hypoplasia: short report, 205House dust mite allergen, Der p 1, in South Manchester homes, absence

of seasonal variation in concentrations, 9285-Hydroxytryptamine

in inhibition of amiloride sensitive transport, 233Pand sensitivity of cough reflex, 895P

HypercapniaIhypoxaemia, cardiovascular effects of isoprenaline, 856Pin obstructive sleep apnoea, effects of posture on flow-volume curves,

524related to diaphragm fatigue, in patients with a thoracoplasty, 880P

Hypercapnic respiratory failure, acute, in chronic obstructive lungdisease, 34

Hyperinflation, inspiratory muscle strength and endurance during, 922Hyperthermia, local, and attenuation of exercise induced asthma, 592Hypertonic saline and bradykinin challenges in asthma, cross refractori-

ness between, 873PHypothalamic-pituitary-adrenal function, in CAO, effect of BDPand prednisolone, 229P

Hypoxaemiabreathlessness, and survival, community study, 847Pand cardiovascular effects of fenoterol, 814/hypercapnia, cardiovascular effects of isoprenaline, 856Pnocturnal, prediction, after thoracoplasty, 879Prefractory, after pneumonectomy, transoesophageal echocardiography:

short report, 60: correspondence, 575Hypoxaemic chronic obstructive airways disease, short term effect of

oxygen on renal haemodynamics, 550Hypoxia

acute and chronic, effects on secretion of vasopressin, renin, andaldosterone, 846P

chronic, effects on contractility of pulmonary resistance vessels, 225Pdirectly causes pulmonary vascular smooth muscle to relax, 224Peffect of hyperinflation on pulmonary artery pressure, 892Phypobaric and normobaric, rats, 892Pinduced pulmonary vasoconstriction in isolated pulmonary arteries,225P

induces endothelial cells to produce growth factor and chemoattractantfor fibroblasts, 225P

influence of mechanical limitation on responses to, 211Ppulmonary reactivity changes, 226P

in resolution of pulmonary hypertension, pulmonary vascular remodel-ling and right ventricular hypertrophy, 227P

and sodium retention, in chronic obstructive pulmonary disease,847P

vasoconstriction, endothelium dependent, 226Pvasorelaxant effect of lemakalim on pulmonary arteries, 227Pand water retention, in chronic obstructive pulmonary disease, 846P

Hypoxic pulmonary vasoconstriction of isolated porcine lungs is notdependent on changes in endogenous NO release, 893P

Idiopathic pulmonary haemosiderosis, form of microscopic poly-arteritis: short report, 988

Idiopathic thrombocytopenic purpura, without underlying lung dis-ease, and invasive aspergillosis: correspondenice, 328

IGF-1 gene expression, increased, and right ventricular hypertrophy inchronically hypoxic rats, 858P

Immunoglobulin G, nebulised, as adjunctive therapy for bronchiectasis,894P

Immunoglobulin replacement therapy, asthma, 254PInflammatory mediators, lung injury, and fibroblast activation in

fibrosing alveolitis, 1064Inflammatory response of respiratory tract, study using nose: editorial,

993Influenza A virus infection, and acute severe deterioration in cystic

fibrosis, 112Inhaled medication

compliance, effect of combining beta-agonists and corticosteroids,845P

high dose, systemic effects, 845Pnight time use, nocturnal symptoms, and morning symptoms, in

asthma, 861Ptechnique, audit in patients and hospital staff, 237P

Inspiratory flow rate through Diskhalers, determinants, 239PIntensive care unit, nosocomial pneumonia, mechanisms and sig-

nificance, 465Interleukin-2 receptor, plasma soluble, monitoring in lung transplanta-

tion, 249PInterleukin-4and 5, localisation of mRNA for, in bronchoalveolar lavage fluid in

atopic asthma, 212Pimmunoreactivity, is localised to mast cells in upper respiratory tract,231P

Interleukin-8effects of intranasal challenge, 893PmRNA expression in sarcoidosis, 215P

Interstitial lung disease, lung function, breathing pattern, and gasexchange, 93

Interstitial pulmonary fibrosis with and without associated collagenvascular disease, two year follow up, 1035

Intravascular oxygen supplementation, 215PIpratropium bromide

delivered orally by metered dose inhaler, does not decrease salivary flowin normal subjects, 891P

effect on posture induced changes of expiratory flow indices in asthma,253P

and oxitropium bromide compared, bronchodilator effect, 865PIpratropium and terbutaline, low and high doses, bronchodilator

reversibility, in COPD, 255PIsoflurane, and vecuronium, for acute severe asthma, sensorimotorimpairment following, reversible: short report, 1078

Isoprenaline, cardiovascular effects, hypoxaemia/hypercapnia, 856PItraconazole, in treatment of pulmonary aspergilloma: correspondence,

328

JJet mixing devices, use with oxygen concentrator, 1060

KKaposi's sarcomabronchopulmonary, in AIDS, 721, 726pulmonary

in Africa, 730lung function abnormalities, 888P

LLactobacillus casei ss rhamnosus, causing fatal lung abscess: short

report, 666: correspondence, 992Laser, NdYAG, endoscopic, in treatment of obstructive tracheal lesions,250P

Laser therapy, preoperative, in resectable bronchogenic carcinoma andsevere coronary artery disease: short report, 1075

Late asthmatic reactions, statistically significant, size, 855PLeiomyoma, primary, of pulmonary vein: short report, 393Lemakalim, vasorelaxant effect on pulmonary arteries, normal and

hypoxia, 227P

1110

Index to titles

LeuCAM adhesion proteins in sarcoidosis, 894PLeucocyte endothelial adhesion molecules, expression, increased in

perennial allergic rhinitis, 232PLeucocytes

asthmatic and normal, effect of nedocromil sodium on migration,243P

eicosanoid production in airways disease, 242PLeukaemia, acute lymphocytic, Corynebacterium pseudodiphtheriticum

pneumonitis, 6 year old child: short report, 838Leukotriene C, effects of exogenous eicosapentaenoic acid on in vitro

eosinophil generation, 241PLeukotriene D4 receptor antagonist ICI 204,219, inhalation effect on

allergen evoked bronchoconstriction, 871PLeukotriene E4, urinary excretion, in exercise induced asthma, 241PLeukotrienes, TNF-alpha, and airflow obstruction in cystic fibrosis,868P

Lipideffect on pulmonary vasoconstriction, 225Pmetabolism, obstructive sleep apnoea, and CPAP, 235P

Lipopolysaccharide, inhaled, bronchial obstructive response, and rela-tion to histamine bronchial responsiveness, 288

Liposomesand alveolar epithelial cells, comparison of effects of oxidants, 246Pfor controlled delivery of drugs to the lung: editorial, 257

Lipoxin A4, effects on airway responses in asthma, 242PLiquid and gaseous oxygen compared, for domiciliary portable use,98

Liquid nitrogen, Der pl levels six months after treatment of houses,219P

Localised fibrous mesothelioma arising in an intralobar pulmonarysequestration: short report, 837

Loop diuretics, inhaled, with adenosine 5-monophosphate, in asthma,time course of change in bronchial reactivity, 872P

Lungabscess, fatal, due to Lactobacillus casei ss rhamnosus: short report, 666:

correspondence, 992cancer

chemiluminescence responses of alveolar macrophages obtained fromeach lung, 250P

communicating diagnosis, 250Pinduced sputum cytology and bronchial biopsy compared in diag-

nosis, 251Pmanagement affected by age related treatment policies, 251Pmediastinal lymph node metastases, is size a valid criterion: editorial,

332mediastinal lymph nodes, pathological assessment, implications for

non-invasive mediastinal staging, 337: correspondence, 842new drugs, 188new perspectives in lung cancer, 19, 53, 188treatment, and haematopoietic growth factors, 119tumour markers in bronchial lavage fluid, 887Psee also specific cancers

functionabnormalities in repaired oesophageal atresia and tracheo-

oesophageal fistula, 1030children, height and age adjustment, 236Pcross sectional studies, height and age adjustment, children, 6-11

years, 707laboratories, audit, West Midlands initiative, 848Pmeasurements, to predict risk of pneumonitis after bone marrow

transplantation, 421respiratory illness, and passive smoking, British children, 220Ptesting in adults with preferential nasal breathing, 719

herniation after pneumonectomy, bronchial compression as result:correspondence, 208

histology in systemic sclerosis, high resolution computed tomography aspredictor, 508: correction, 738

infections, epithelial yd T cells, 253Pinflammation, acute, studies of airspace epithelial permeability, rat

model, 244Pinjured, conventional and novel respiratory therapy, 555injury

acuteimpaired neutrophil rheology an early event, 244Pwith increased pulmonary endothelial permeability, porcine cardio-pulmonary bypass, 244P

new look at pulmonary circulation, 743and cardiopulmonary bypass, pilot study of infused pentoxifylline inmodel of ARDS, 244P

inflammatory mediators, and fibroblast activation in fibrosing alveoli-tis, 1064

pharmacotherapy, 651left, hypoplasia with horseshoe lung: short report, 205sounds: editorial, 671

intensity, in emphysema and normal subjects at standardised airflows,674

transplantationa, antitrypsin deficiency in emphysema, prevalence, 248Pbronchial mucosal blood flow changes after, 877Pearly bacterial and fungal infections, 885Pfor emphysema, ventilation-perfusion relationships after, 248Psingle

obstructive sleep apnoea in recipients, 878Psteroid therapy and airway complications following, 248Psurvival, influence of pulmonary pressures and resistances, in non-

suppurative lung disease, 247Pvalue of donor lung lavage in identification of postoperative infection

following, 248Pvalue of plasma soluble IL2-r monitoring, 249P

volumes, static, in healthy subjects assessed by helium dilution duringocclusion of one mainstem bronchus, 848P

see also PulmonaryLymph node tuberculosis, unusual spinal tuberculosis after adequate

chemotherapy, immunocompetent man: short report, 986Lymphadenopathy and pure red cell aplasia, associated with broncho-

centric granulomatosis: short report, 131Lymphocytes

infiltration in nasal mucous membrane in allergic rhinitis, 232Pand subset numbers, in blood, lavage and pleural fluid, tuberculosis,

513; correspondence, 1085Lymphoma, primary intrathoracic, AIDS related, 223P

MMacrophage aggregates in rats exposed to dust from wool mill air,mechanism of formation, 213P

Macrophage lymphocyte interactions in sarcoidosis, effects of steroid,215P

Magnetic particles in lung, measurement by pneumomagnetometry,888P

Maori community, "credit card" asthma self management plan, 890PMask, to modify inspired air temperature and humidity, effect on exercise

induced asthma, 446Masks, oxygen, misleading labelling and packing, 543Maximal expiratory pressure, measurement, effect of holding the lips,

961Mediastinal compression, fatal, as late complication of surgical

plombage: short report, 321Mediastinal lymph node metastases in lung cancer, is size a valid

criterion: editorial, 332Mediastinal lymph nodes, in lung cancer, pathological assessment,

implications for non-invasive mediastinal staging, 337: correspondence,842

Mediastinal malignancy, ultrasound guided biopsy through the supra-clavicular approach, 377

Mediastinum, thoracic duct cyst: short report, 325Mesam 4, and home sleep studies, 234PMesothelioma

localised fibrous, arising in an intralobar pulmonary sequestration: shortreport, 837

malignant, Portsmouth, 1982-91, 851Pmalignant pleural, surgeon's role, 851P

Metabisulphite, in asthma, effect of amiloride on airway response,872P

Meter dose inhaler, pressurised, and Bricanyl Turbohaler compared, inadult asthmatics, 238P

Methacholineairway hyperreactivity, 885Pairway responsiveness, and urinary sodium excretion, 856Pchallenge, repeatability, asthmatic children, transcutaneous oxygen

tension, 804induced bronchoconstrictionand dose-response relation of nebulised salbutamol, 873Peffect on spectral characteristics of breath sounds in asthma, 680effects on cough receptor sensitivity to inhaled capsaicin and tartaric

acid, 441wheeze, airflow and lung volume, relationship between, 253P

with inhaled frusemide, and cyclooxygenase inhibition, 853Plog dose-response curve slope, relationship to sensitivity to, and starting

airway calibre, 242Preduced subjective awareness of bronchoconstriction provoked by,

elderly, 410responsiveness, and peak expiratory flow, in aluminium potroom asthma

diagnosis, 292Methotrexate

low dosefor rheumatoid arthritis, and acute pneumonitis, 628Pneumocystis carinii complicating: correspondence, 67

in steroid dependent asthma, long term results, 254PMicrobial flora of the trachea during intubation for upper abdominal

surgery, 818Microthoracotomy, endoscopy assisted: editorial 489, 850P

initial experience, 490

1111

Index to titles

Mini-Wright peak expiratory flow meter, non-linearity, effect on

calculation of diurnal variation, 891PMini-Wright peak flow meter performance, changes after prolonged

use, 890PMKS 492, inhaled, bronchodilator effectiveness assessed in normalhuman subjects, 242P

Morning symptoms, nocturnal symptoms, and night time inhaler use inasthma, 861

Mucinous cystadenoma of the lung, and adenocarcinoma: short report,

129Mucociliary function, ciliary ultrastructure, and ciliary orientation, in

Young's syndrome, 184Multinucleated cells in bronchoalveolar lavage from AIDS patients,240P

Multiple cystic pulmonary hamartomas: short report, 1076Multivariate analysis, and reduction of number of intermediate V:Q

scans, 236PMuscle

biopsy specimens, and respiratory disease in SLE, 957respiratory and quadriceps, strength in chronic adult onset asthma,216P

Myasthenia gravis, repetitive stimulation of phrenic nerves, 640Mycobacteria

non-tuberculous, Nottingham 1979-91, 875Popportunistic infection, in bronchiectasis, 251P

Mycobacterium kansasii and M tuberculosiisclinical features compared, 876Ppulmonary infections, radiography compared, 876P

Mycobacterium malmoense and M tuberculosis, pulmonary infections,radiography compared, 875P

Mycobacterium tuberculosisdrug resistance, Karachi, Pakistan, 227Pinfection, vaccinated with BCG, generation of cytolytic T cells, 695specific antibody, measurement in pulmonary tuberculosis, clinical

value, 270Myocardial infarction

oesophageal dissection after thrombolytic treatment: short report, 835stable, serum cytokines and salivary platelet aggregation factor, 870P

NN-Acetylcysteine, high dose, effect on glutathione and cysteine levels in

bronchoalveolar lavage and lung tissue, 246PNasal breathing

obligate, adults, 236Ppreferential, adults, lung function testing, 719

Nasal cannulas, variability of inspired oxygen concentrations, 609;correspondence, 1086

Nasal challenge with bradykinin and histamine, airway and blood flow

changes, 894PNasal continuous positive airway pressure, domiciliary, in obstructive

sleep apnoea, 878PNasal intermittent positive pressure ventilation, in chronic respira-

tory failure, 859PNasal mucosa, normal human, cytokine immunoreactivity, 896PNasal mucous membrane, in allergic rhinitis, infiltration by lympho-

cytes, 232PNasal ventilation

role of expiratory positive airway pressure, 858Pto facilitate weaning in patients with chronic respiratory insufficiency,

715v doxapram, in treatment of type II respiratory failure complicating

chronic airflow obstruction, 858Psee also Nose

Nebulised bronchodilator therapy in hospital, cost effectiveness of

education, 240PNebuliser compressor service, district, costs, 863PNebulisers, home

assessment of patients, survey of present practice in Yorkshire, 863P

lung function and symptom scores during three years, 863P

provision, Yorkshire, 863PNeck circumference, and other clinical features, in obstructive sleep

apnoea syndrome diagnosis, 101Neck osteopathy causing bilateral diaphragmatic paralysis: short report,

201Nedocromil sodium

aerosol and dry powder compared, in exercise induced asthma, 230Peffect on leucocyte migration in normal and asthmatic leucocytes,243P

inhibits histamine release within proximal asthmatic airways in vivo,212P

Neural stimulation, differential responses of pulmonary arteries, 226PNeuropeptides, differential responses of pulmonary arteries, 226PNeutrophilic alveolltis in Sweet's syndrome: short report, 572Neutrophils

elastase levels and oxygen requirement after multiple trauma, 245P

peripheral blood, novel, rapid technique for isolating, in vitro functionand in vivo migration in the lungs, 243P

rheology, impaired, early event in acute lung injury, 244PNew perspectives on basic mechanisms in lung disease, 1063, 1064Nicotine patches v placebo, 234 hospital patients, 886PNilutamide pneumonitis, eight patients, 622Nitric oxide release, inhibited by L-NAME, vascular effects, 891P5-Nitro-2-(3-phenylpropylamino) benzoic acid, a chloride channel

"blocker" which alters channel gating, 233PNitrogen dioxide, effect on synthesis of tumour necrosis factor (e byhuman bronchial epithelial cells in vitro, 245P

Nocturnal symptoms, morning symptoms, and night time inhaler use inasthma, 861P

Non-adrenergic, non-cholinergic nervous system, role in overnightvariation of airway calibre in asthma, 243P

Non-small cell bronchogenic carcinoma, preoperative computedtomography of brain, 106

Non-small cell lung cancerexpression of different cytoskeletal peptides, 249Pperioperative staging, practice of cardiothoracic surgeons: editorial, 1, 3;

correspondence, 327survival, in relation to epidermal growth factor receptor expression,860P

Normal healthy subjects, how normal is normal, 240PNormocapnia, in obstructive sleep apnoea, effects of posture on flow-volume curves, 524

Nosein study of inflammatory response of respiratory tract: editorial, 993see also Nasal

Nosocomial pneumonia, in the intensive care unit, mechanisms andsignificance, 465

Notices, 67, 139, 206, 328, 484, 576, 761, 844Nucleolar organiser regions as marker of growth rate in squamous cell

carcinoma of the lung, 778Nutritional support in chronic obstructive lung disease: editorial, 141

0Obstructive airways disease, bronchodilator response, interpretation,

429Obstructive sleep apnoea

airway assessment, somnofluoroscopy, computed tomography, andcephalometry, 150

basal metabolic rate, 878Pand bodybuilders with large necks, 879Pbreath holding time, 880Pdomiciliary nasal continuous positive airway pressure, 878Peffects of nasal CPAP, 235Peffects of posture on flow-volume curves during normocapnia and

hypercapnia, 524habitual snoring with and without, importance of cephalometric

variables, 157neck circumference and other clinical features in diagnosis, 101night time blood pressure, 216Pphase angle changes and breathing, 879Pin single lung transplant recipients, 878Purinary cyclic GMP, 878P

Oesophageal atresia, and tracheo-oesophageal fistula, repaired, lungfunction abnormalities, 1030

Oesophageal carcinoma, surgical treatment, and Laurence O'Shaugh-nessy: correspondence, 842

Oesophageal dissection after thrombolytic treatment for myocardialinfarction: short report, 835

Oilseed rape, and bronchial reactivity and IgE, 885POncology ward, paediatric, pseudo-outbreak of tuberculosis, 220PO'Shaughnessy, Laurence, at Dunkirk 1940: correspondence, 842Osteomyelitis, vertebral, presenting with pleuritic chest pain and

bilateral pleural effusions: short report, 395Osteoporosis

corticosteroids, and bone disease, oral and intravenous bisphosphonatescompared, 854P

involutional and corticosteroid associated, and vertebral fractures:correspondence, 207

Oximetry, 24 hour ambulatory, to monitor response to assisted ventila-tion with NIPPV, 215P

Oxitropium, in COPD, predictors of symptomatic and functionalbenefit, 865P

Oxitropium bromideand ipratropium bromide compared, bronchodilator effect, 865Pand salbutamol, effect on oxygen desaturation in COPD, 21 1P

Oxygenconcentrations, inspired, in nasal cannulas, variability, 609: correspond-

ence, 1086concentrators

assessment for prescription and reassessment, 222Pclinical description of those prescribed, England and Wales, 221Pand jet mixing devices, 1060prescription, 847P

1112

Index to titles

delivery, transtracheal: new techniques, 57liquid, portable, and exercise ability in severe respiratory disability,

781liquid and gaseous compared, for domiciliary portable use, 98masks, misleading labelling and packing, 543saturation changes after nebulised salbutamol in acute asthma, 220Pshort term effect on renal haemodynamics in hypoxaemic chronic

obstructive airways disease, 550supplementation, intravascular, 215Ptension, transcutaneous, gas exchange during exercise, 848Ptherapy

domiciliaryEast Anglian GP survey, 864Plong term, community management, outline plan, 864P

long term, short term variability of saturation in patients beingassessed for, 864P

transport, relation between oxygen delivery and consumption, 971uptake kinetics, applied to COPD, 210P

Oxygenation, brain tissue, in chronic obstructive lung disease, effect ofaminophylline, 1025

pPaediatric oncology ward, pseudo-oubreak of tuberculosis, 220PPamidronate, intravenous, for osteoporosis associated with cortico-

steroid dependent lung disease, 932Pancreatic carcinoma, retroperitoneal silicosis mimicking, in Alpineminer with chronic lung silicosis: short report, 480

Parkinson's disease, effects of dopaminergic stimulation on airwaydynamics and respiratory muscle strength, 880P

Passive smokingdoes not change lung permeability acutely, 860Pexposure in children, 801, 861Prelation to spirometric values in children, 850Prespiratory illness and lung function in British children, 220P

Patent foramen ovale, shunting through: correspondence, 575Peak expiratory flow

in children passively exposed and not exposed to cigarette smoke,circadian rhythm, 801

diurnal variability, in CAO, 865Pdiurnal variation, different methods for calculating, 882Peffect of number of readings a day on diurnal variation, 845Pmeasurement, validity in assessing reversibility of airflow obstruction,

162meter, non-linearity, effect on calculation of diurnal variation, 891Pvariability, repeatability of measures, for community studies, 230P

Peak flow measurement: editorial, 903Peak flow meter

and asthma drug prescribing, data analysis, 884Pnon-linearity, influence on recorded PEF variability, 891Pin obstructive airways disease, comparison of use before and after

1 October 1990, 237Pperformance, changes after prolonged use, 890Pportable, accuracy, 904

Peak inspiratory flow rates in acute asthma, are they adequate forefficient use of a Turbohaler, 239P

Pectus excavatum, and congenital bronchial atresia with regionalemphysema: short report, 1082

Pentoxifylline, infused, in ARDS model, lung injury and cardiopulmo-nary bypass, 244P

Peribronchiolitis, clinicopathological features, 217PPeripheral T cell receptor Va gene used in atopy and atopic asthma,

restriction, 853PPet ownership, and associated morbidity in asthma, 210PpH measurements, gastro-oesophageal reflux and asthma, 881PPharmacotherapy in lung injury, 651Pharyngeal size during nasal positive airway pressure in sleep apnoea,

effect of reduced expiratory pressure, 809Phosphoinositidase C isoforms, multiple, presence in bovine trachealsmooth muscle, 213P

Photodynamic therapy, endoscopic, for malignant endobronchialobstruction, 251P

Phrenic nerves, repetitive stimulation, in myasthenia gravis, 640Physiotherapy, before elective abdominal surgery, evaluation, 249PPlasma leakage, effects of bradykinin and histamine compared, 232PPlasma membrane receptors, modulation in fine tuning of cell

behaviour, 563Platelet activating factorinduced bronchoconstriction and circulating white cell responses,

failure of salmetrol to inhibit, 948induced bronchoconstriction and leucopenia are not inhibited by

salmeterol, 255Pand non-specific bronchial hyperresponsiveness, 255P

Platelet aggregation factor, salivary, in acute severe asthma, acutemyocardial infarction, and stable asthma, 870P

Platelet kinetics in asthma with and without aspirin intolerance, 533Pleural abrasionnew method of pleurodesis: correspondence, 138, 575

Pleural adhesions, pneumothorax, and air transport: short report, 833Pleural biopsies, audit, argument for setting up pleural biopsy service,849P

Pleural effusionamylase rich, analysis of amylase isoenzyme in differential diagnosis,887P

audit of clinical investigation, 734as manifestation of temporal arteritis: short report, 398

Pleural empyemamicrobiology, 850Psecondary to pneumonia, thoracocentesis regimen versus tube drainage,

821Pleuroperitoneal shunts for malignant pleural effusion, long term

follow up, 861PPlicatic acid induced histamine release from BAL cells, 214PPlombage, surgical, fatal mediastinal compression as late complication:

short report, 321Pneumocystis cariniiDNA amplification from saline mouth rinse, 857Pinfection, latent, absence in post-mortem lung samples, 856Pmolecular genetic analysis shows close relationship to ustomycetous red

yeast fungi, 856Ppolymerase chain reaction detection in asymptomatic HIV infection,223P

pneumonia, 305in AIDS, polymerase chain reaction and immunofluorescence com-

pared, 857Patypical, 857Pcomplicating low dose methotrexate treatment for rheumatoid arthri-

tis: correspondence, 67in HIV antibody positive patients, diagnosis by simple outpatient

assessments, 1005subclinical, in small cell lung cancer, 857P

Pneumomagnetometry, for measurement of magnetic particles in thelung, 888P

Pneumoniaacute bacterial and atypical, community acquired, Saudi Arabia, 115after stroke, 874Pcommunity acquired: editorial, 329blood CD4 and CD8 lymphocyte numbers, 253Pcriterion based audit, 874Pinduced sputum as diagnostic tool, 874P

due to Q fever, antibiotic treatment, 276fulminant, Aeromonas hydrophila, in a fit young man: short report, 482nosocomial, in the intensive care unit, mechanisms and significance,

465pleural empyema secondary to, thoracocentesis versus tube drainage in

treatment, 821Pneumonitis

acute, associated with low dose methotrexate for RA, 628after bone marrow transplantation, lung function measurements to

predict risk, 421nilutamide associated, eight patients, 622

Pneumothoraces, spontaneousmanagement, audit, 887Ppersistent air leak, optimum time of surgical intervention, 222P

Pneumothoraxin pleural adhesions, and air transport: short report, 833secondary to septic pulmonary emboli, in tricuspid endocarditis: short

report, 1080Pollution

respiratory effects, 885Pand respiratory morbidity, how much do we accept? 391; correspondence,

762Polyarteritis, microscopic, and idiopathic pulmonary haemosiderosis:

short report, 988Polyethylene shrink wrapping, causing occupational asthma (paper

wrapper's asthma): short report, 759Polymerase chain reaction

amplification of two mycobacterial DNA sequences, IS6110 and 65kDaantigen gene, in tuberculosis diagnosis, 690

in rapid diagnosis of tuberculosis: editorial, 264in tuberculous pleurisy diagnosis, 265

Polysomnography system, computerised, evaluation, 234PPositive expiratory pressure breathing, effect in cystic fibrosis:

correspondence, 66Positron emission tomography

to measure regional structure-function correlations in chronic obstruc-tive lung disease, 914

for in vivo quantification of pulmonary beta-adrenoceptor density,853P

Post-thoracotomy, use of Flutter VRP1 device, 236PPosture, effects on flow-volume curves during normocapnia and hyper-

capnia in obstructive sleep apnoea, 524Poverty, and tuberculosis, 849PPre-employment chest x ray films, for health service staff, who needs

them, 877P

1113

Index to titles

Precipitins, and specific IgG antibody to Aspergillus fumigatus, in chestunit population, 48

Prednisolone"abruptly stopping" compared with "tailing off," in acute asthma,228P

short course, in chronic obstructive airways disease, bone turnoverduring, 418; correspondence, 1084

Pressurised metered dose inhaler technique, how good are generalpractitioners, 237P

Procaterol induced bronchodilation, effects on cough receptor sensi-tivity to inhaled capsaicin and tartaric acid, 441

Propofol sedation for outpatient bronchoscopy, improved recovery after,246P

Prostacyclininhaled, differential effect on airway calibre in hyperresponsive subjects,872P

intravenous, effects in severe chronic obstructive pulmonary disease,893P

Prostaglandin E2, in protective effect of frusemide, 895PProstaglandins, in regulation of active chloride transport, 233PProstanoids, inhibitory, evidence of role in beneficial effects of frusemide

for exercise induced asthma, 797Protease inhibitor phenotype, relation to serum elastin peptide

concentration, working men, 937Pseudolung sounds, measurement of attenuation by animal lung and

chest wall, 880PPseudomonas aeruginosa

extrapulmonary sites, in adults with cystic fibrosis, 426infection, seasonal onset, and cystic fibrosis, 109mucoid, infection, in cystic fibrosis, role of alginate, 6pyocyanin from perturbs respiratory epithelium by intracellular redox

cycling, 252Ppyocyanin slows human ciliary beating via cyclic AMP dependentmechanism, 869P

Pseudomonas cepaciainfection, increased incidence in adult cystic fibrosis centre, 866Pserum IgG antibodies to, in adults with cystic fibrosis, 252P

Psychosocial factors in brittle asthma, 209PPulmonary

adenocarcinoma, primary, and alveolar atypical hyperplasia, clin-icopathological study of 10 cases, 1041

arteriovenous malformations, quantification of right to left shunt at restand during exercise, 790

aspergillosis, chronic necrotising, caused by A niger in a mildlyimmunocompromised host: short report, 570

circulation, in acute lung injury, a new look, 743complications, after long term amiodarone treatment, 372disease, rural African hospital, 228Pemboli, septic, pneumothorax secondary to, in tricuspid endocarditis:

short report, 1080embolism, management, 825emphysema, detection and quantification by computed tomography:

editorial, 1001endothelial permeability, three probe portable system for assessment,893P

functionin chronic renal failure, effects of dialysis and transplantation:correspondence, 763

and symptoms in workers exposed to wood dust, 84heart disease, and abnormal right ventricular systolic and diastolic

function, 847PKaposi's sarcoma, in Africa, 730lymphangioleiomyomatosis, possible aetiological factors, 217Pmetastatic calcification, localised, associated with pulmonary artery

obstruction, 174neoplasm, endobronchial actinomycosis mimicking: short report, 664sequelae of chlorine gassing, 236Psurgery, prophylactic digitalisation, 41valvotomy, surgical closed, for critical pulmonary stenosis, implications

for balloon valvuloplasty era, 179vascular smooth muscle, hypoxia induced relaxation, 224P

Pure red celi aplasia and lymphadenopathy, associated with broncho-centric granulomatosis: short report, 131

Pyocyanin from P aeruginosa perturbs respiratory epithelium by intra-cellular redox cycling, 252P

QQ fever, causing pneumonia, antibiotic treatment, 276

RRadiographic chemical sensitisation in a radiographer, 229PRadiotherapy, endobronchial, effect on tumour morphology and lung

function, 250PRenal haemodynamics, short term effect of oxygen, in hypoxaemic

chronic obstructive airways disease, 550Renin, secretion, effects of acute and chronic hypoxia, 846PResidual volume and total lung capacity, predictive equations calculatedfrom radiographs, random sample, Michigan population, 519

Respiratory disability, severe, portable liquid oxygen and exerciseability, 781

Respiratory distress syndrome, tumour necrosis factor in bronchoal-veolar secretions, dexamethasone treatment, infants, 44

Respiratory function laboratories and technicians, British ThoracicSociety survey, 848P

Respiratory insufficiency, chronic, nasal ventilation to facilitate wean-ing, 715

Respiratory musclefunction in patients with severe scoliosis, 848Pstrength in chronic asthma, 849Ptraining, in chronic airflow limitation, controlled trial, 598

Respiratory obstruction from mediastinal bronchogenic cyst, recurrent:short report, 660

Respiratory symptomsin childhood, time trends over 24 year period, 853Ppostal survey, young adults, Bergen, Norway, 884Pand self reported asthma, prevalence, student population, 209P

Respiratory workload, assessment against provision of respiratoryphysicians, 222P

Resting energy expenditureestimation in chronic lung disease, comparison of ventilated hood andmouthpiece systems, 864P

TNFa, and cachexia in cystic fibrosis, 868PReviewers used from 1 October 1991 to 30 September 1992, 1088Rheumatoid arthritis

bronchial reactivity and airways obstruction, 854Plow dose methotrexate treatment, Pneumocystic carinii pneumonia

complicating: correspondence, 67Rhodococcus equi, endobronchial mass with lung abscess, and AIDS:

short report, 62Right to left shunt, quantification at rest and during exercise, inpulmonary arteriovenous malformations, 790

Right ventricular hypertrophy in chronically hypoxic rats is associatedwith increased IGF-1 gene expression, 858P

SSalbutamoland asthma deaths, New Zealand, 1969-76, case-control study, 210Pand BRL38227 compared, in asthma, 254Pdoes not influence incidence of chest infection after upper abdominal

surgery in high risk patients, 249Peffect of addition of increasing doses to salmeterol, 855Pand fenoterol compared, 882P

cardiovascular and metabolic effects, 882Pclinical study, 882P

nebulisedin acute asthma, oxygen saturation changes after, 220Pand adrenaline, comparison of bronchodilator potencies and effectson bronchial reactivity in mild asthmatic subjects in vivo, 874P

dose-response relation against bronchoconstriction induced bymethacholine, 873P

and oxitropium bromide, effect on oxygen desaturation in COPD,211P

Salmeteroleffect of six week course on bronchial reactivity, 230Pfailure to inhibit circulating white cell responses and bronchoconstric-

tion induced by platelet activating factor, 948inhaled, chronic dosing in exercise induced asthma, 255Pmetered dose inhaler, paradoxical bronchoconstriction associated with,254P

PAF induced bronchoconstriction and leucopenia are not inhibited by,255P

v salbutamol, in moderate asthma, cost effectiveness compared, 883PSalmeterol xinafoate in asthmacompared with nedocromil sodium, 883Pcompared with salbutamol, 883P

Sarcoidosiseffects of steroid on macrophage lymphocyte interactions, 215PIL-8 mRNA expression, 215PLeuCAM adhesion proteins, 894Ppulmonary, B lymphocyte accumulations, 964

Sclerotherapy, oesophageal, chylothorax as complication: short report,134

Scoliosis, severe, respiratory muscle function, 848PSensorimotor impairment following prolonged ventilation with iso-

flurane and vecuronium for acute severe asthma, reversible: short report,1078

Shoulder pain and breathlessness, 216PShunting through a patent foramen ovale: correspondence, 575Shuttle walking test of disability, in patients with chronic airways

obstruction, development, 1019Silicosis, retroperitoneal, mimicking pancreatic carcinoma, in Alpineminer with chronic lung silicosis: short report, 480

Sleep apnoeaANP release, 235Pinduction with negative pressure ventilation, in chronic obstructive lung

1114

Index to titles

disease, 612obstructive, neck circumference and other clinical features in diagnosis,

101phase angle changes and breathing, 879Psee also Obstructive sleep apnoea

Sleep and breathing in obesity, effects of fluoxetine, 235PSleep disordered breathingand Mesam 4, 234Pmild to moderate, 4-5 year old children, daytime behaviour, 220P

Sleep disturbance, due to respiratory symptoms, 855PSmall cell lung cancer

relapse, treatment with initial combination chemotherapy carboplatin,etoposide, and epirubicin, 369: correspondence, 668

subclinical Pneumocystis carinii, 857PSmoke, cigarette, circadian rhythm of peak expiratory flow in children

passively exposed and not exposed to, 801Smokers

airway immunopathology, bronchus associated lymphoid tissue, 886Pintegrity of alveolar-capillary barrier and alveolar surfactant system,

603and non-smokers, intra-alveolar macrophage numbers, 437

Smokingchildren, the problem and the way forward: editorial, 485current smoking, leanness, and physical inactivity, interaction between,

in prediction of hip fracture, 861Ppassive, lung function, and respiratory illness, British children, 220Prelation to serum elastin peptide concentration, working men, 937and smoking habit, hospital staff attitudes, 850Psee also Passive smoking

Snorers, breath holding time, 880PSnores, frequency content in humans, 879PSnoring, habitual, with and without obstructive sleep apnoea, importance

of cephalometric variables, 157Sodium

dietary, effect on severity of bronchial asthma, 360low, diet, effect on asthma in general practice, 256P

Sodium metabisulphiteand exercise induced asthma, cross refractoriness between, 873Pinduced bronchoconstriction, attenuated by carbonic anhydrase inhib-

itor, 234PSodium retention, and hypoxia, in chronic obstructive pulmonary

disease, 847PSolitary pulmonary nodule, bronchography complementing fibreopticbronchoscopy to evaluate, 886P

Somatic gene therapy, for hereditary respiratory diseases, recent

advances, 315Somnofluoroscopy, in airway assessment, obstructive sleep apnoea,

150Sonography, endobronchial, feasibility and preliminary results: new

techniques, 565Spinal tuberculosis, unusual, after adequate chemotherapy for lymphnode tuberculosis in an immunocompetent man: short report, 986

Sputuminduced

cell counts, to investigate airway inflammation in asthma, 25as diagnostic tool in community acquired pneumonia, 874Pmethod of assessing airway inflammation in asthma, 212P

induction, in cytological diagnosis of bronchogenic carcinoma, 887Psol phase proteins, and elastase activity, in clinically stable bronchiecta-

sis, 88Squamous cell carcinoma of the lung, nucleolar organiser regions as

marker of growth rate, 778Stents expandable metal

for tracheal obstruction, permanent or temporary, cautionary tale: shortreport, 757

insertion under direct vision via a fibreoptic bronchoscope, preliminaryexperience, 250P

Steroid(s)dependent asthma, auranofin treatment, 349; correspondence, 992effects on macrophage lymphocyte interactions in sarcoidosis, 215Pinhaled, preterm infants with respiratory symptoms at follow up, 910tapering, in acute asthma, 845Ptherapy, and airway complications following pulmonary transplantation,248P

see also CorticosteroidsStreptococcus pneumoniae

cell associated, and stimulation of oxidative response of neutrophils,870P

interference with oxidative response of neutrophils, and oxidation ofcytochrome C, 869P

producing respiratory burst inhibitor, characterisation, 869Psusceptibility to killing by reactive oxygen species, 869P

Stroke, pneumonia after, 874PSweet's syndrome, and neutrophilic alveolitis: short report, 572Systemic lupus erythematosus, respiratory disease in, muscle biopsy

specimens, 957

Systemic sclerosis, high resolution computed tomography as predictorof lung histology, 508; correction, 738

TT cell recognition of antigen, and lung diseases, 127Tartaric acid, inhaled, cough receptor sensitivity to, effects of methacho-

line induced bronchoconstriction and procaterol induced bronchodila-tion, 441

Technetium-99m DTPAlung clearance

diagnostic value in P carinii pneumonia in AIDS: correspondence,138

evaluation, 888Ppersistent alveolar increased permeability to in advanced HIV infection:

correspondence, 575Temazepam, effect on tracheobronchial mucus clearance, 298Temporal arteritis, pleural effusion as manifestation: short report, 398Terbutalineand budesonide, effects on bronchial reactivity to allergen in mild atopic

asthma, 231Pinfused, with and without oral, in brittle asthma, side effects, 256Pinhaled

sex differences in hypokalaemic, chronotropic, and electrocardio-graphic effects, 882P

sex differences in hypokalaemic and electrocardiographic effects,1056

and ipratropium, low and high doses, bronchodilator reversibility, inCOPD, 255P

plasma, HPLC measurement, brittle asthma, 884PTerfenadine, in nocturnal asthma, 230PTetrachloroisophthalonitrile, inducing asthma: short report, 760Textile workers, symptom free, repeatability of histamine bronchial

challenge as measured by dose response, 889PTheophylline plasma estimation, Acculevel and HPLC compared,255P

Thigh muscle strength in chronic asthma, 849PThoracic duct cyst in the mediastinum: short report, 325Thoracocentesis regimen versus tube drainage in pleural empyema

secondary to pneumonia, 821Thorax, annual report October 1991-September 1992, 1087Three probe portable system for pulmonary endothelial permeability

assessment, 893PThrombocytopenia, immune, complicating pulmonary tuberculosis:

short report, 396Thrombolytic treatment for myocardial infarction, oesophageal dissec-

tion after: short report, 835Tine testing HIV positive patients, 877PTotal lung capacity and residual volume, predictive equations calculated

from radiographs, random sample, Michigan population, 519Trachea

epithelium, endothelin, vasopressin, and substance P like immuno-reactivity, rabbit, 1044

lesions, obstructive, endoscopic NdYAG laser treatment, 250Pmicrobial flora, during intubation for upper abdominal surgery, 818obstruction, expandable metal stents, permanent or temporary, cau-

tionary tale: short report, 757Tracheo-oesophageal fistula, and oesophageal atresia, repaired, lung

function abnormalities, 1030Tracheobronchial clearance

acute effect of inhaled bradykinin, normal humans, 952modulation by inhaled bradykinin and [desArg9]-bradykinin in normal

subjects, 860PTracheobronchial epithelium dysplasia, expression of proliferating

cell nuclear antigen, 249PTracheobronchial mucus clearance, effect of temazepam, 298Tracheobronchial obstruction, treatment with bronchoscopic dia-

thermy resection, 886PTransbronchial lung biopsy, multiple, complications following, 886PTranscutaneous oxygen tension, and repeatability of methacholine

challenge in asthmatic children, 804Transdiaphragmatic sniff pressure, with catheter mounted pressure

transducers, normal range, 881PTransepithelial potential difference, effect of pulmonary infection,233P

Transoesophageal echocardiography, in diagnosis of refractory hypox-aemia after pneumonectomy: short report, 60; correspondence, 575

Transplantation, and pulmonary function in chronic renal failure:correspondence, 763

Transtracheal oxygen delivery: new techniques, 57Trauma, multiple

endotoxin, antiendotoxin core antibodies, and oxygen requirementafter, 245P

neutrophil elastase levels and oxygen requirement after, 245PTuberculin positive children: editorial, 768Tuberculosis

and AIDS, is the "white plague" up and coming? 223P

1115

Index to titles

among health service employees, 224Paudit of standard contact procedure, 227Pcalculated annual risk of infection, south west Ireland 1983-90, 228Pcontact tracing

are British Thoracic Society guidelines still appropriate: short report,984

results, Blackburn 1982-90, 224Pdiagnosed in contact clinic, Leeds TB survey 1991, 876Pin the elderly, presentation and outcome, Leeds tuberculosis survey

1991, 223Pextrapulmonary, Lothian 1980-1989, delay from start of symptoms to

diagnosis, 877Pextrathoracic, presentation and outcome, Leeds TB survey 1991,877P

genitourinary, occurs proportionately less than expected in Indiansubcontinent ethnic population in the UK, 876P

immune thrombocytopenia complicating: short report, 396lymphocytes and subsets in blood, lavage and pleural fluid, 513:

correspondence, 1085M tuberculosis specific antibody measurement, clinical value, 270national survey of notifications, England and Wales, 1988, 770notification, number of cases never reported, 1015PCR amplification of IS611 0 DNA, 876Pand poverty, 849Pprediction of later breakdown and positive Heaf test reaction, Asian

schoolchildren, 776pseudo-outbreak, paediatric oncology ward, 220Prapid diagnosis, new approaches: editorial, 264school microepidemic: correspondence, 208side effects of therapy in the elderly, 875Pspinal, unusual, after adequate chemotherapy for lymph node tubercu-

losis in an immunocompetent man: short report, 986standardised notification ratio, simple way of assessing service needs,875P

in the third world: correspondence, 327three drug regimen as best treatment, 224Pwho treats and how effectively, Leeds tuberculosis survey 1991, 222Pyield from contact tracing, Birmingham 1987-9, 875P

Tuberculous meningitis, management: editorial, 577Tuberculous pleurisy, polymerase chain reaction in mycobacterial DNA

detection, 265Tumour markers in bronchial lavage fluid in lung cancer, 887PTumour necrosis factor, in bronchoalveolar secretions, respiratory

distress syndrome, dexamethasone treatment, infants, 44leukotrienes, and airflow obstruction in cystic fibrosis, 868Presting energy expenditure and cachexia in cystic fibrosis, 868Psynthesis by bronchial epithelial cells, effect of NO,, 245P

Turbohalerdevice to show patient efficiency, 889Pand peak inspiratory flow rates in acute asthma, 239P

UUltrasound guided percutaneous cutting biopsy for diagnosis of pulmo-

nary consolidations of unknown aetiology, 457Upper abdominal surgery, microbial flora of trachea during intubation,

818Upper airway obstruction, abnormal movement of arytenoid region as

cause: short report, 840

Ustomycetous red yeast fungi, molecular genetic analysis shows closerelationship to Pneumocystis carinii, 856P

VV:Q scans, intermediate, can multivariate analysis reduce number,236P

Vascular cells, effect of heparin, 634Vascular leakage, effect of local hyperthermia, 232PVasoactive substances, within tracheal epithelium, rabbit, 1044Vasopressin, secretion, effects of acute and chronic hypoxia, 846PVecuronium, and isoflurane, for acute severe asthma, sensor motor

impairment following, reversible: short report, 1078Ventilation

collateral, and gas exchange, normal lung, 211Peffect on avian antigen concentration in an animal laboratory, 889P-perfusion relationships, after single lung transplantation for emphy-

sema, 248Psustained maximum voluntary, causes diaphragm fatigue, 858P

Ventilometer, hand held spirometer, evaluation, 229PVertebral fractures in steroid dependent asthma and involutional

osteoporosis: a comparative study: correspondence, 207Vertebral osteomyelitis, presenting with pleuritic chest pain and

bilateral pleural effusions: short report, 395Viral infections, role in lung disease of cystic fibrosis: editorial, 69Visceral pleural biopsy, percutaneous, with fenestrated cup biopsy

forceps: technical note, 753Vitamin A and E concentrations in cystic fibrosis, 867PVitronectin receptor mediates macrophage phagocytosis of apoptotic

eosinophils, 240PVocal cord palsy, right, at bronchoscopy, 247P

WWalking tests

in severe airflow limitation, 211Pshuttle and six minute, comparison, 236P

Water retention, and hypoxia, in chronic obstructive pulmonary disease,846P

Web 2086, no steroid sparing effect in asthmatic patients requiring inhaledcorticosteroids, 871P

Wedge-bellows spirometer tubes, microorganisms in, 862PWegener's granuloma

1975-1985 clinical data, 217Phistological features, 217Pprognosis, treatment and cause of death, 217P

Weightlifting exercise, and chronic airflow limitation, trial, 70Wheeze in childhood

airway function 25 years later, 221Peducational attainment and employment 25 years later, 253P

Wilms's tumour, childhood, exercise capacity in survivors, 220PWood dust, pulmonary function and symptoms of exposed workers, 84Wool mills, macrophage aggregates in rats exposed to dust from air,mechanism of formation, 213P

Wright pocket and mini-Wright peak flow meters, comparison,230P

yYoung's syndrome, mucociliary function, ciliary ultrastructure, and

ciliary orientation, 184

1116