Lecture 2- Physiology and Effects of Flight

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    Human Physiology & Effects of

    Flight

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    understanding how the body and mind can beaffected in flight as well as why they are affectedin flight.

    clear understanding and overview of the many andvaried physiological situations that can interferewith safe flight.

    prevent impairment and reduce the risk of a

    human factorsrelated incident or accident. being knowledgeable about the physiology of the

    body in the flight environment further increasessafety.

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    Human Factors and Flight Safety

    Why Important?

    Flight physiology and human factors both

    have an impact on flight.

    More than 70 percent of aviation accidents

    and incidents are in some way related to

    human factors.

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    Accident vs. Incident

    An accident is one incident too many.

    No accident occurs without a series ofincidents happeningbeforehand.

    Its a chain of events that will eventually end up as anaccident unless someone breaks that chain.

    Contributing factor to an accident is probably associatedwith an incident of varying significance that could have

    been averted and the accident prevented. Always look for the contributing factors, because those

    usually can be controlled. The final event and the resultingaccident cannot be reversed.

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    Flight physiology is the most important part of

    human factors. Its the human element of human

    factors and safe flight, and it has a direct effect onperformance.

    Knowing flight physiology, being aware of its

    effects on performance, and maintaining a high

    index of suspicion when performance becomessubstandard will continue to make everyone a

    better and safer pilot.

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    Human Factors & Flight Physilogy

    the effects of fatigue, hypoglycemia, illness, noise, andother medical and psychological issues.

    Flight physiology is how the body and mind work in the

    flying environment. It includes such topics as understanding how our organs

    function, what keeps them from functioning in a hostileenvironment, and what the pilot can do to protect thesefunctions before and during flight.

    It is essential to safe flight.

    Flight physiology, therefore, is an integral part of humanfactors and safe flight.

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    H

    LS E

    L

    FRAMEWORK OF HUMAN FACTORS

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    S - Software (procedures, documentation, symbology,etc.)

    H Hardware

    (technology, machine, equipment)

    E - Environment

    (weather, temperature, noise)

    L - Liveware (human)(people, leader, follower, human element

    L I V E W A R E

    Core of the model comprised ofhuman operators, mostflexible and critical component in the system.

    S H E L L

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    The model is also important in explaining why the

    physiology of flight is important, since the human

    element is obviously crucial and central and everyaspect of physiology will affect every other

    interaction as defined in the model.

    Human factors are how these interfaces and

    interactions ultimately affect performance; humanfactors are a dynamic process.

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    Flight Physiology Objectives

    prevention of incapacitation or

    impairment, whether physical or mental.

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    Incapacitation & Impairment

    Incapacitation is defined as being incapable of performingexpected normal activity.

    Mental incapacitation is the minds inability to use proper

    judgment, reasoning, and decision making. Beyond that, mental incapacitation turns into

    neurological incapacitation, whereby the signals fromthe brain fail to use the sensory information and data fromthe eyes, ears, touch, smell, and the like.

    Physical incapacitation refers to the bodys inability tofunction in an expected way. The end result in any of theseincapacitating or impairing situations is an unsafe andpoorly performing pilot.

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    HUMAN ANATOMY

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    ELO #3

    Identify the components of the circulatory

    system that transport oxygen throughout the

    human body.

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    how the body should work under ideal and

    controllable situations, and raise the level of

    awareness of what can, and often does,happen in less than ideal conditions.

    brain, musculoskeletal, gastrointestinal,

    metabolic, and circulatory.

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    What is Physiology?

    The study of human systems' integrated

    functions and the processes by which theymaintain the body functions.

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    What is Human Physiology?

    Human physiology is the science of themechanical, physical, and biochemical

    functions of humans body system,which include the organs, and the

    cells of which they are composed.

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    Nervous system

    Consists of the Central Nervous System (which is the brainand spinal cord) and peripheral nervous system

    The brain is the organ of thought, emotion, and sensoryprocessing, and serves many aspects of communication andcontrol of various other systems and functions.

    The special senses consist of:

    Vision > eye

    Hearing > ear Taste > tongue

    Smell > nose

    The eyes, ears, tongue and nose gather information about thebody's environment.

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    Musculoskeletal System

    Consists of the human skeleton(which includes bones, tendons,ligaments and cartilage) and

    attached muscles.

    It gives the body basic structureand the ability for movement. Inaddition to their structural role,the larger bones in the body

    contain bone marrow, the site ofproduction of blood cells.

    Also, all bones are major storagesites for calcium and phosphate.

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    Gastrointestinal system

    Consists of the mouth,

    esophagus, gut (small and large

    intestines), and rectum, as well

    as the liver, pancreas,

    gallbladder, and salivary glands.

    It converts food into small,

    nutritional, non-toxic molecules

    for distribution by thecirculation to all tissues of the

    body, and excretes the unused

    residue.

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    Circulatory System

    Consists of the heart and bloodvessels (arteries, veins,capillaries).

    The heart propels thecirculation of the blood, whichserves as a "transportationsystem" to transfer oxygen,fuel, nutrients, waste products,

    immune cells, and signallingmolecules (i.e., hormones)from one part of the body toanother.

    The blood consists of fluid that

    carries cells in the circulation,including some that move from

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    Circulatory System

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    FUNCTIONS OF THE

    CIRCULATORY SYSTEM

    Oxygen and nutrient (fuel) transport to the cells.

    Transport of metabolic waste products to organ

    removal sites.

    Assists in temperature regulation.

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    Components of theCirculatory System

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    Plasma

    O2

    Red Blood Cell

    CO2

    CO2 O2

    CO2

    O2

    hemoglobinmolecule

    Blood transport ofO2 and CO2

    O2 molecule

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    Metabolic System

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    Respiratory System

    Respiratory system

    consists of the nose,

    nasopharynx, trachea,an lungs

    It brings oxygen from

    the air and excretes

    carbon dioxide and

    back into the air.

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    The respiratory system consists of passages andorgans that bring atmospheric air into the body

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    Respiratory System

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    ELO #4

    ACTION: Select the functions and types of

    respiration.

    CONDITION: Given a list.

    STANDARDS: IAW FM 3-04.301.

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    FUNCTIONS OF THE

    RESPIRATORY SYSTEM

    Intake of Oxygen [O2]

    Removal of Carbon Dioxide [CO2]

    Maintenance of body heat balance

    Maintenance of body acid base balance [pH]

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    Phases of Respiration

    Active PhaseINHALATION

    Passive PhaseEXHALATION

    Breathing in Breathing out

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    COMPONENTS OF THE RESPIRATORY SYSTEM

    Nasal/Oral

    pharynx

    Trachea

    Bronchi

    Bronchiole

    Alveolar

    DuctsAlveoli

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    Law of Gaseous Diffusion

    Gas molecules of higher pressure move in thedirection of gas molecules of a lower pressure

    PO2 = 100mmHg PO2 = 40mmHg

    PO2 = 70 mmHg PO2 = 70 mmHg

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    Blood GasExchange

    PCO2 = 46 mm

    PO2 = 100 mmPCO2 = 40 mm

    PO2 = 40 mm

    PO2 = 100 mm

    PCO2 = 40 mmPCO2 = 46 mm

    PO2 = 1 - 60 mm

    Arterial Capillary

    Hemoglobin Saturation 98%

    O2

    O2

    CO2

    O2

    CO2

    O2

    Venous Capillary

    Hemoglobin Saturation 75%

    Tissue Alveoli

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    Oxygen transport in the blood:

    dependent on thepartial pressure of oxygen.

    pO2

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    PERCENT COMPOSITION OFTHE ATMOSPHERE REMAINS

    CONSTANT

    BUT PRESSURE

    DECREASES

    WITH ALTITUDE

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    SIGNIFICANT PRESSURE ALTITUDES

    ALTITUDE PRESSURE

    FEET mm/HG ATMOSPHERES

    0 760 1

    18,000 380 1/2

    34,000 190 1/4

    48,000 95 1/8

    63,000 47 1/16

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    Physical characteristics of the atmosphere

    The atmosphere is like an ocean of air that surrounds thesurface of the Earth.

    It is a mixture of water and gases.The atmosphere extends from the surface of the Earth to

    about 1,200 miles in space.

    Gravity holds the atmosphere in place.

    The atmosphere exhibits few physical characteristics;however, it shields the inhabitants of the Earth fromultraviolet radiation and other hazards in space.

    Without the atmosphere, the Earth would be as barren asthe moon.

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    The atmosphere consists of several concentric layers, each

    displaying its own unique characteristics.

    Each layer is known as a sphere.

    Thermal variances within the atmosphere help define thesespheres, offering aviation personnel an insight into atmosphericconditions within each area.

    Between each of the spheres is an imaginary boundary, knownas a pause.

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    Troposphere

    Troposphere extends from sea level to about 26,405 feet

    over the poles to nearly 52,810 feet above the equator

    Stratosphere

    Tropopause to about 158,430 feet (about 30 miles)

    Mesosphere

    Stratopause to an altitude of 264,050 feet (50 miles) Thermosphere

    From 264,050 feet (50 miles) to about 435 miles above

    the Earth

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    Standard Pressure and Temperature Values at 40 Degrees Latitude for Specific Altitudes

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    Composition of the Air

    78 Percent Nitrogen N2

    21 Percent Oxygen

    1 Percent Other

    .03 percent CO2

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    Partial Pressure

    (Daltons Law)760 mm Hg

    47 --- mm/Hg

    95 ---

    190 ---

    380 ---

    523 ---

    760 ---

    21%O

    2

    78% N2

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    Boyles Law

    This law states that the volume of a gas is inversely proportional to thepressure (temperature remaining constant). This applies to all gases.V1/V2 = P2/P1 (V1 is the initial volume of the gas, V2 is the finalvolume, P1 is the initial pressure on the gas volume, and P2 is the finalpressure).

    In other words, if the pressure of the gas decreases with thetemperature unchanging, then its volume increases and vice versa (Fig.3-2). In dealing with gas expansion in the body, a correction must bemade for the ever-present water vapor; therefore, the formula nowbecomes: V1/V2 = (P247 mm Hg)/(P146 mm Hg) (Fig. 3-3). Water-

    vapor pressure at body temperature is 47 mm Hg. Such characteristics applied to the body explain The expansion of

    gases trapped within such moist areas as the middle ears, sinuses,stomach, and intestines.

    These are all actual or potential cavities within which moist air ispresent and can become trapped and expand like any other gas; hence,

    the physiological topic of trapped gases, which will be discussed inCha ter 5 re ardin altitude h siolo .

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    Charles Law

    Charles Law states that the volume of gas is directly proportional to the temperature (pressureremaining constant).

    This applies to all gases. This law has no direct physiological significance because body temperatureremains fairly constant.

    It does, however, explain the fact that pressure within supplemental oxygen containers will decrease

    if the ambient temperature surrounding the storage container decreases, even when no oxygen hasbeen used, such as at altitude.

    Daltons Law

    Since the atmosphere is a mixture of gases, and each gas has its own pressure at any giventemperature within a given volume, it is important to also be familiar with the physics of thecombined pressures.

    Daltons Law states that the total pressure of a gas mixture is the sum of the individual pressure (alsocalled partial pressure) that each gas would exert if it alone occupied the whole volume.

    Figure 3-3 The effect of water on gas expansion.

    Or expressed mathematically: PT= P1 + P2 + Ps + Pn; where PTis the total pressure of the mixtureof gases and the P value is the partial pressure of each gas, which is determined by multiplying thepercentage of the individual gas times the total pressure.

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    Physiological Divisions Of The

    Atmosphere

    Ph i l Di i i f th At h

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    TROPOSPHERE

    Sea level to flight level 300 -

    600 depending on temperature,

    latitude and season.

    Physical Divisions of the Atmosphere

    STRATOSPHERE

    IONOSPHERE

    EXOSPHERE

    MOUNT EVEREST 29,028 FEET

    1200 miles

    600 miles

    50 miles

    Tropopause

    Physiological Zones of the

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    Physiological Zones of the

    Atmosphere

    EFFICIENT ZONE: Sea level to 10,000 feet

    SPACE EQUIVALENT ZONE: 50,000 feet and above

    DEFICIENT ZONE: 10,000 to 50,000 feet18,000 ft

    63,000 ft

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    Composition of the Air

    78 Percent Nitrogen N2

    21 Percent Oxygen

    1 Percent Other

    .03 percent CO2

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    Hypoxia

    Hyperventilation

    Pressure effect changes

    Trapped Gas Disorders

    Evolved-Gas Disorders

    Visions 54

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    GENERAL EFFECTS ON THE

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    GENERAL EFFECTS ON THE

    HUMAN BODY

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    Altitude Physiology

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    The physiology of oxygen in the body 50

    Review of respiration physiology 51

    Carbon monoxide and ozone 67

    Decompression of cabin altitude 68

    Trapped gases 70

    Evolved gas disorders 75

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    Hypoxia

    Hyperventilation

    Pressure effect changes

    Trapped Gas Disorders

    Evolved-Gas Disorders

    Visions

    Gravity Force G

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    Contents

    Types of Hypoxia

    Causes of Hypoxia

    Effect of Hypoxia

    Overcoming Hypoxia

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    Hypoxia

    State ofoxygen [O2] deficiency

    in the blood cells and tissuessufficient to cause

    impairment of function.

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    Types of Hypoxia

    Hypemic

    Stagnant

    Histotoxic

    Hypoxic

    H i H i

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    ReducedpO2in the lungs

    (highaltitude)

    Body tissue

    Redblood cells

    Hypoxic Hypoxia

    A deficiencyin Alveolaroxygen

    exchange

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    Hypoxic hypoxia

    Hypoxic hypoxiaoccurs when not enough oxygen isin the air or when decreasing atmospheric pressuresprevent the diffusion of O2 from the lungs to thebloodstream.

    Aviation personnel are most likely to encounter thistype at altitude. It is due to the reduction of the O2 athigh altitudes

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    H i H i

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    An oxygendeficiencydue toreduction inthe oxygen

    carryingcapacity ofthe blood+

    +

    +

    +

    ++

    +

    ++

    +

    +

    +

    + ++

    Hypemic Hypoxia

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    Hypaemic, or anaemic,

    Hypaemic, or anaemic,hypoxia is caused by a reductionin the oxygen-carrying capacity of the blood.

    Anaemia and blood loss are the most common causes ofthis type.

    Carbon monoxide, nitrites, and sulpha drugs also causethis hypoxia by forming compounds with haemoglobinand reducing the haemoglobin that is available tocombine with oxygen.

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    Reducedbloodflow

    Bloodmovingslowly

    Adequateoxygen

    Red blood cells

    not replenishingtissue needsfast enough

    Stagnant

    Hypoxia

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    stagnant hypoxia

    In stagnant hypoxia, the oxygen-carrying capacity ofthe blood is adequate but, circulation is inadequate.

    Such conditions as heart failure, arterial spasm, andocclusion of a blood vessel predispose the individual tostagnant hypoxia.

    More often, when a crew member experiences extremegravitational forces, disrupting blood flow and causingthe blood to stagnate.

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    Histotoxic Hypoxia

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    Red blood cellsretain oxygen

    Inability of thecell to acceptor use oxygen

    Poisoned tissue

    Adequateoxygen

    Histotoxic Hypoxia

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    This type results when there is interferencewith the use of O2 by body tissues.

    Alcohol, narcotics, and certain poisonssuchas cyanideinterfere with the cells ability touse an adequate supply of oxygen.

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    Hypoxia Symptoms

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    Hypoxia Symptoms

    what you feel

    (subjective)Air hunger

    Apprehension

    Fatigue

    Nausea

    Headache

    Dizziness

    Denial

    Hot & Cold Flashes

    Euphoria

    Belligerence

    Blurred Vision

    Numbness

    Tingling

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    Symptoms vary from one person to another and,therefore, are subjective.

    Aviation personnel commonly experience mild hypoxia ataltitudes at orabove 10,000 feet.

    Those who fly must be able to recognize the possiblesigns and symptoms because the onset of hypoxia issubtle and produces a false sense of well-being.

    Crew members are often engrossed in flight activitiesand do not readily notice the symptoms of hypoxia.

    However, most individuals experience two or threeunmistakable symptoms or signs that cannot beoverlooked. 72

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    Susceptibility to hypoxia varies with individuals

    Several factors determine individual susceptibility

    1. O2 Deficiency - Onset Time and Severity

    The onset time and severity of hypoxia vary with the

    amount of oxygen deficiency.

    Crew members must be able to recognize hypoxia andimmediately determine the cause.

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    2. Self-Imposed Stress

    Self-imposed stressors, such as tobacco and alcohol,

    increase the physiological altitude.

    Physiological Altitude

    An individuals physiological altitude, the altitude that the

    body feels, is as important as the true altitude of a flight.

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    3. Smoking

    The haemoglobin molecules of RBCs have a 200- to300-times greater affinity for carbon monoxide than foroxygen

    Cigarette smoking significantly increases the amountof CO carried by the haemoglobin of RBCs; thus, itreduces the capacity of the blood to combine withoxygen

    Smoking 3 cigarettes in rapid succession or 20 to 30cigarettes within 24 hours before a flight may saturatefrom 8 to 10 percent of the haemoglobin in the blood.

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    4. Alcohol.

    Alcohol creates histotoxic hypoxia. For example, an individual who has

    consumed 1 ounce of alcohol may have a physiological altitude of 2,000feet

    5. Individual Factors Metabolic rate, diet, nutrition, and emotions greatly influence an

    individuals susceptibility to hypoxia.

    6. Ascent Rate (Climb Rate) Rapid climb rates affect the individuals susceptibility to hypoxia. High

    altitudes can be reached before the crew member notices serioussymptoms.

    7. Exposure Duration The effects of exposure to altitude relate directly to an individuals lengthof exposure. Usually, the longer the exposure, the more detrimental theeffects. At

    higher the altitude, the shorter the exposure time required beforesymptoms of hypoxia occur.

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    8. Ambient Temperature

    Extremes in temperature usually increase the metabolic rate of thebody. A temperature change increases the individuals oxygen

    requirements while decreasing the tolerance of the body to hypoxia. With these conditions, hypoxia may develop at lower altitudes than

    usual.

    9. Physical Activity When physical activity increases, the body demands a greater

    amount of oxygen. This increased oxygen demand hypxia to takeeffect faster

    10. Physical Fitness

    An individual who is physically conditioned will normally have ahigher tolerance to altitude problems than one who is not. Physical fitness raises an individuals tolerance ceiling.

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    In aviation, the most importanteffects of hypoxia are those related,either directly or indirectly, to thenervous system

    Nerve tissue has a heavyrequirement for oxygen. Brain tissueis one of the first areas affected by

    an oxygen deficiency

    A prolonged or severe lack ofoxygen destroys brain cells.

    The expected performance time isfrom the interruption of the oxygen

    supply until the crew member losesthe ability to take corrective action.

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    Aviators Performance Time VS Height

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    Hypoxia Signs

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    Hyperventilation

    Cyanosis

    Mental confusion

    Poor Judgment

    Lack of muscle coordination

    yp gwhat we see in you

    (objective)

    St f H i

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    Stages of Hypoxia

    Indifferent Stage

    Compensatory Stage

    Disturbance Stage

    Critical Stage

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    Indifferent Stage

    Altitudes:

    Air: 0 - 10,000 feet

    100% O2: 34,000 - 39,000 feet

    Symptoms: decrease in night vision

    @ 4000 feet acuity

    color perception

    Compensatory Stage

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    Compensatory Stage

    Altitudes:Air: 10,000 -

    15,000 feet

    100% O2: 39,000 - 42,000

    feet

    Symptoms: impaired efficiency,drowsiness, poor judgment and

    decreased coordination

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    CAUTION!!!!

    Failure to recognize yoursigns and symptoms may

    result in an aircraft mishap.

    Di t b St

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    Disturbance Stage

    Altitudes

    Air: 15,000 - 20,000 FEET

    100% O2: 42,000 - 44,800 FEET

    Disturbance Stage

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    Disturbance Stagesymptoms

    Memory

    Judgment

    Reliability

    Understanding

    Coordination

    Flight Control

    Speech

    Handwriting

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    Time of Oxygen

    1 Minute

    2 Minutes

    3 Minutes

    4 Minutes

    5 Minutes

    6 Minutes

    Put Back on Oxygen

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    Disturbance Stage

    Signs

    Hyperventilation

    Cyanosis

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    Critical Stage

    Altitudes

    Air: 20,000 feet and above

    100% O2: 44,800 feet and above

    Signs: loss of consciousness,convulsions and death

    Factors modifying hypoxia

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    y g ypsymptoms

    Pressure altitude

    Rate of ascent

    Time at altitude

    Temperature

    Physical activity

    Individual factors

    Physical fitness

    Self-imposed stresses

    DEATH

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    keep self imposed stresses out of the aircraft

    DEATH

    Drugs

    Exhaustion

    Alcohol

    Tobacco

    Hypoglycemia

    ALCOHOL

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    ALCOHOL

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    Expected performance time for a crew member

    flying in a pressurized cabin is reducedapproximately one-halffollowing

    loss of pressurization such

    as in a:

    RDRapidDecompression

    Expected Performance

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    FL 430 & above 9-12 secondsFL 400 15 - 20 secondsFL 350 30 - 60 seconds

    FL 300 1 - 2 minutes

    FL 280 2 1/2 - 3 minutes

    FL 250 3 - 5 minutes

    FL 220 8 - 10 minutes

    FL 180 20 - 30 minutes

    Expected Performance

    Times

    Hypoxia

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    Hypoxia

    Prevention

    Limit time at

    altitude

    100% O2

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    Individuals who exhibit signs and symptoms of hypoxiamust be treated immediately.

    Treatment consists of giving the individual 100 percent

    oxygen.

    If oxygen is not available, descent to an altitude below10,000 feet is mandatory.

    When symptoms persist, the type and cause of thehypoxia must be determined and treatment administeredaccordingly.