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Protease ResearchCenter ApprovedThe State Board of Higher Education approved the establishment of the NDSUCenter for Protease Research. The move came at the board’s November 21-22,2002 meeting.

Its mission will be to establish a competitive biomedical research center. Objec-tives include developing therapeutic inhibitors for matrixmetallo proteinases throughsynthesis, targeting and delivery of biopharmaceutics/drug design; organizingsymposiums, seminars and proposal writing workshops and facilitating facultygrant reviews; and recruiting fellows and graduate students.

The center, which will be directed by Mukund Sibi, professor of chemistry, will usegrants from private and governmental agencies as its primary source of funding.

From: It’s Happening, December 4, 2002

COBRE Principle Investigators (left to right):Inder Seghal (Assistant Professor, Pharmacy)Sanku Mallik (Associate Professor, Chemistry)Mukund Sibi (Professor, Chemistry) - Center DirectorGregory Cook (Associate Professor, Chemistry)Stefan Balaz (Assistant Professor, Pharmacy)Kenton Rodgers (Associate Professor, Chemistry).

www.ndsu.edu/cobre

Chem-News 2 February 2003

from: The Fargo Forum

New construction in North DakotaState University’s research park iscreating major economic ripples, andcould help reverse the exodus of areacollege graduates, state and localdignitaries said Monday.

A study by NDSU professor LarryLeistritz estimates the economicimpact of construction in the school’sResearch & Technology Park at $81.9million.

The figure includes $54.8 millionstemming from Research II, which willhouse the Center for NanoscaleScience and Engineering.

Lawmakers joined university officials tobreak ground for Research II anddedicate the $6.2 million Research Ibuilding.

“If we’re going to build a future thatkeeps people here, but brings othersback … it’s about creating opportuni-ties, and that’s what this research parkdoes,” Gov. John Hoeven said.

NDSU President, Joseph Chapman,said the research park “brings anopportunity to North Dakota that,frankly, just did not exist before.”

Research II will be valued at $26million to $28 million when completedin spring 2004. Footings will beinstalled before winter, said PhilBoudjouk, NDSU Vice President ForResearch, Creative Activities andTechnology Transfer.

Foss Associates of Fargo is theproject’s general contractor.

Leistritz’s study measured the impactof Research I construction at $14.9million.

The facility currently employs about80 staff and researchers, and focusesmainly on coatings and materials.

Phoenix International Corp., the park’smain tenant, employs 165 workers andhad an estimated construction impactof $12.2 million.

“On a scale of big deals and smallmatters, this is a really big deal – abig deal for NDSU and for NorthDakota,” said Sen. Byron Dorgan, D-N.D.

In addition to the construction impact,the park will generate $9.3 million intax revenue, the study said.

That figure was based on NDSU’s goalof having a $100 million annualresearch budget.

NDSU anticipates a $75 millionresearch budget for 2002-03, the studysaid.

Dorgan said Department of Defensecontracts, which historically havebeen awarded to states like Massa-chusetts, California, Texas and NewYork, will fund most of the research.

NDSU received $27 million in 2002 todevelop an ultra-low-power battlefieldsensor system and is also developingcoatings to prevent aircraft fromcorroding and barnacles from stickingto Navy ships.

“I’m not bashful about doing this,”Dorgan said. “This money’s going tobe spent. I’m not adding money to thefederal budget. The question is whereit’s going to be spent.”

Research II will have space for 125researchers and support staff,including a variety of engineers andchemists, Boudjouk said.

California-based Alien Technology Co.has already started transferring part ofthe $200 million in technology toNDSU. The company and universityare two of five partners in a $1.4million Department of Defensecontract that could drive NDSU to theforefront of sensor technologydevelopment.

Alien’s Technologies, known asNanoBlock and Fluidic Self Assembly,allow researchers to create microchipsthe size of pepper flecks at a rate of 6million an hour. The circuits conform toalmost any shape and could be usedfor anything from detecting spoiledfood to helping locate soldiers.

“This is a cross-cutting technology,”Boudjouk said.

Alien’s chief executive officer, JeffJacobsen, recounted how he learnedin his first meeting with NDSU officialsthat 90 percent of the university’spolymer and chemistry graduates wereleaving the state to take jobs at 3M.

“The technology has the potential forincreasing economic wealth of themany daughters, sons and grandchildren of the people here in NorthDakota,” Jacobsen said.

Research Park Generates $81.9M in Economic Help

http://www.ndsu.nodak.edu/cnse

Chem-News 3 February 2003

North Dakota Experimental Program toStimulate Competitive Research

Poster Session at ND EPSCoR’s Annual Conference at University of ND,Grand Forks.

Dr. Mark Hadley from Alien Technology instructs CNSE faculty,staff and students in the use of a high-end profilometer usedto examine flexible substrates with “NanoBlocks” assembledwith Alien’s patented technology. The instrument is located inthe new cleanroom in Dunbar Hall, Room 50.

Synthesis Station-01, CNSE engineer Bernd Scholz uses onecomponent of combinatorial synthesis and screeningequipment being installed in Dunbar Hall, Room 56. Theequipment is being used for a marine coatings developmentprogram supported by the Office of Naval Research.

Center for Nanoscale Science andEngineering update....

EPSCoR State Conference

The theme was “Research Opportunities and Forging Partner-ships.” Pre-conference workshops included electronic resources,molecular modeling and tribal college distance learning.

Events included a keynote address by Senator Byron Dorgan;“Forging University-Private Sector Partnerships,” by F. LeeWillams, University of Oklahoma; a review of capacity-buildingopportunities and accomplishments for science, engineering andmathematics research in North Dakota; presentations by federalagency officials in the development of competitive large-scale,multi-investigator projects; forging university/private sectorpartnerships; and student poster and paper presentations.

www.ndsu.nodak/epscor

Chem-News 4 February 2003

Last Spring was a busy time oftransition for the Boudjouk Group.Moving from Dunbar to the ResearchI building occurred “effectively” onApril 1, 2002. At the same time, thiswas a period of initiation for severalnew research projects that will occupythe group in the coming years.

The new laboratory (Room 232)achieved 100% functionality in Junewith the installation of our new solventpurification system. The systemutilizes dual column chromatographyto remove moisture and oxygen fromorganic solvents. Our many thanks goto Harlan Isensee, Research Special-ist, and his invaluable assistance insetting this system up. Stop by andsee us some time!

There are several personnel changesassociated with the Boudjouk labora-tory. Seok-Bong Choi and Tom Readyhave new appointments in the Centerfor Nanoscale Science and Engineer-ing (CNSE) as Senior ResearchScientists. They will continue theirwork in the Boudjouk laboratory at R1in conjunction with several existingand forthcoming research projects(see below).

CNSE has hired two additionalemployees who will work in theBoudjouk laboratory. Dr. JohnsonThomas is a new post-doctoralresearcher associate who will arrive inFargo Jan. 1, 2003. Dr. Thomasreceived his Ph.D. from MahatmaGhandi University in Kottayam, Kerala,India, worked in industry, but comes tous from the Laboratoire De ChemieDes Polymeres Organiques at theUniversity of Bordeaux, France. He willwork on both the Anti-Fouling/ Foul-Release Coatings and MicrosensorArray projects (described below).

Shane Stafslien is our new ResearchSpecialist who started work in October2002. Shane received his B.S. in

The New Laboratory Facility

Microbiology from NDSU in 1999 andhas worked in industry since then,most recently for the PRACS institute(Fargo) as a Team Leader / AnalyticalChemist. Shane will work on both theAnti-Fouling/ Foul-Release Coatingsand Microsensor Array projects(described below).

Microbial, bacterial, weed, and sea life(i.e. tubeworms & barnacles) fouling ofnaval ship hulls and ballast tanks posemany problems and threats for mari-time operation. These problems andthreats include reduced operationalspeed, increased fuel consumption,reduced payload size, increased threatof catastrophic corrosion & destructionof the hull, translocation of non-indigenous nuisance species from onepart of the world to another. Forenvironmental reasons, the anti-foulingagent tributyltin has been effectivelybanned from use as of Jan. 1, 2003,and most experts believe that copperanti-fouling agents will be banned inshort order.

On July 1, 2002, CNSE received a$3.5 M research grant from the Officeof Naval Research to develop Combi-natorial / High Throughput (C/HT)methods for the discovery and analysisof anti-fouling / foul-release coatings.The principal investigator for thisproject is Philip Boudjouk (Chemistry)and Co-PI’s on the project are DeanWebster (Polymers & Coatings), TomReady (CNSE), and Seok-Bong Choi(CNSE). Project manager for this effortis Greg McCarthy. CNSE will takedelivery on C/HT equipment thisAugust & September which includesrobotic synthesis, analysis / character-ization, and informatics work stations.Normally, a person performing 4experiments a day would take 4 – 6months to develop and characterize aneffective coating formulation. Whenfully operational, it is anticipated thatCNSE’s automated C/HT operation willenable a single researcher to synthe-size & characterizize 700 coating

formulations in 1 week. To our knowl-edge this will be the first fully auto-mated C / HT coatings developmentfacility in the world.

Current electronic devices operateutilizing the movement of charge (viaelectrons) through a circuit. However,charge is susceptible to strongelectromagnetic radiation or pulsesand this problem becomes accentu-ated with very small devices. Electronspin (a magnetic component) is muchless susceptible to this phenomenon.Hence, major research efforts areunderway to develop electronicdevices that are based on themovement of (magnetic) spin ratherthan charge. These devices are oftenreferred to as “spintronic” devices.

CNSE is the recipient of a one-year$0.5 M research grant from DefenseAdvanced Research Program Activityto develop polymeric magneticmaterials for use in spintronic de-vices. This project will involvecollaboration with researchers at theUniversity of California at SantaBarbara. The principal investigator forthis project is Philip Boudjouk(Chemistry) and Co-PI’s on theproject are Seok-Bong Choi (CNSE),and Tom Ready (CNSE). The projectmanager for this effort is Dean Grier.

The Boudjouk laboratory is alsoengaged with CNSE in its DefenseMicro Electronics Activity fundedproject for the development of newbattlefield sensors.

Members of the Boudjouk group havealso been on the road recently,attending:a) the 1st International Conference onNanotechnology & Micromechanics inWalsea, Maui (Choi, Ready, Al-Badri),

Boudjouk Lab, Research and Technology Park

Personnel Changes

Anti-Fouling/Foul-Release CoatingsCombinatorial Chemistry Project

“Spin-Tronics” Project

Microsensor Project

Recent Meetings

By: Tom Ready

cont’d page 5

Chem-News 5 February 2003

McCarthy Lab, Dunbar Hall 157

This has been an exciting year for theMaterial Characterization Laboratory.We’ve had to endure, among otherthings, “Aliens”, a new lab manager,and the death of our lab mascot, a fishnamed “Nano”. Nevertheless, thisyear hasn’t come without manyblessings! Wonderful people havecome and gone, projects have rolled inand out, and a new baby has joinedthe crew!

Dean Grier, our beloved MCL director,has been busy working with the newCenter for Nanoscale Science and

Engineer-ing(CNSE),where heis theAssistantDirectorforResearchandDevelop-ment.Thoughbusy with

many meetings and deadlines. Deanhas helped to keep the MCL moving inthe right direction during this transitionperiod for the lab. On July 13, Deanand his wife Kris became the proud

parents of Kate Frances, who we aredelighted to report is doing quite well.

Eric Jarabek was promoted to MCLmanager this past July. He has beenworking on several materials researchprojects, while trying to keep everyonehappy by making sure the MCLinstruments are running well. If youcan’t find Eric in the MCL, you’ll likelyfind him working in the dungeons ofDunbar in CNSE’s new Cleanroom. Healso spends a good deal of time withhis girlfriend, Laura Mergen, a formerMCL undergraduate research fellow.We are eagerly watching her left handfor any sign of a diamond.

Christine Bultema, a junior inchemistry, has taken part in severalmaterials projects with externalcorporations involving X-ray Diffraction(XRD) Analysis. In addition to herXRD work, she is in charge ofmaintenance, calibration, and sampleanalysis for the Elemental Analyzer,and was also responsible for theintroduction of the MCL’s very firstmascot.

We are mourning the sudden death ofour first mascot, a beta fish namedNano. During the Thanksgiving break,

he jumped out of his container andwas later found dried out about a footaway. Nano has since beenmournfully replaced by a new fish, abeautiful blue and red beta namedAlpha. He is affectionately known as“Alpha the beta”.

Jordan Sand, a sophomore studyingbiotechnology, is our resident Snoodmaster. Jordan has been instrumentalin helping set up and maintain theCleanroom. He plays a very criticalrole in doing literature research on avariety of topics related to CNSEinitiatives.

Another new but now familiar face inthe MCL is Matt Beeler. Matt, who ishoused in the MCL, is part of CNSE’sMicrosensors project. He keeps busydoing market analyses, patentresearch, and is currently investigatingbusiness plans related to CNSE spin-off companies. He is Jordan’s archnemesis when it comes to Snood.

We are missing Renee Peterson, an“MCLer” who graduated last spring.She is currently attending graduateschool at the University of NorthernColorado, pursuing a doctoral degreein chemical education and doing

By: Dean Grier, Eric Jarabek, Christine Bultema

Bo Boudjouk Lab cont’d

New Graduate Students for 2002-2003

Jason Rolfstad from Chariton, Iowa joined Dr. Hamilton’s Lab Matt Rex from Owatonna, MN joined Dr. Campiglia’s Lab Marina Santos from Rosario, Argentina joined Dr. Campiglia’s Lab Nicole Miller from Fargo, ND joined Dr. Sun’s Lab Misty Tomchuk from Fargo, ND joind Dr. Rasmussen’s Lab Xiaomin Jin from Zhejiang, China joined Dr. Cook’s Lab Robert Kargbo from Sierra, Leone joined Dr. Cook’s Lab Rajesh Subramaniam Perintalmanna,India joined Dr. Sibi’s Lab

Em

ily a

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atie

.

b) 2002 ONR Program Review in SanDiego, California (Boudjouk, Choi,Ready) ,

c) the 11th International Congress onMarine Corrosion and Fouling in SanDiego, California (Choi, Ready) ,

d) DMEA/Univ. Alaska-Fairbanks /NDSU Microsensor meeting inFaribanks, Alaska (Boudjouk, Choi,Ready),

e) Integrated Nanosystems 2002,Berkeley, California (Ready), e) TheWinter Materials Research Sympo-sium meeting, Boston, Massachusetts(Choi, AL-Badri), f) Bio-DetectionTechnologies, Washington D.C.(Ready).

Chem-News 6 February 2003

Chemistry Lab Groups

The Tallman lab and the Corrosiongroup have a spirit of changesurrounding them. After movinginto the Research and TechnologyPark last March, we are startingto settle into the facilities at thetech park.

After graduating with a B.S. inMay, Matt Dewald decided tostay on with the group as agraduate student in polymers andcoatings. This summer, we alsohad two summer REU students,Jennifer Sleeper from CentralCollege in Pella, IA and MichaelJaquith from Michigan TechUniversity in Houghton, MI. Jenworked with Amy Richter on theelectroless deposition ofpolypyrrole onto Al2024-T3 whileMike worked with Matt Dewald onthe electrodepostion ofpolypyrrole onto Al2024-T3. Thegroup enjoyed a trip to Medoraand end of summer picnic withthe REU students.

This fall three students defendedtheir Ph. D. Thesis, Jie He,Guoliang Chen, and Chur Vang,while Thane Underdahl will bedefending his M.S. thesis shortlyafter the holiday break. Jie He isstaying on with the CorrosionGroup as a post doc continuinghis research utilizing the Scan-ning Vibrational Electrode Tech-nique.

Shortly after Thanksgiving, wewelcomed a new post doc, KirillLevine, into the group. Hepreviously held a post docposition at the University ofCincinnati. Kirill received his B.S.from Leningrad PolitechnicalInstitute and Ph.D. from theRussian Academy of Science.

The Tallman LabBy: Amy Richter

At Christmas time the Rodgers Lab Group: Front row- Renee (Rodgers daughter),Gudrun-Lukat Rodgers, Indrani Chakraborty, (Husband) Yong Tang, Lei Tang.Back row: Hongshen He, Kent Rodgers, Nathan Silvernail and Doug Linder.

ThThe Rodgers Lab Group

The Hamilton Lab

Darla Powell, Nicole Poppinga, Jason Rolfstad, Karen Beckman, Dr. Hamilton andDave Schultz.

Chem-News 7 February 2003

Chemistry Lab Groups

Chemistry Junior, Paul Barron joinedDr. Sun’s group in September 2002.Paul worked as a REU student inDr. Sun’s lab during the summer 2002.He is working on the synthesis andcharacterization of pentaazadentateporphyrin-like rare-earth complexes forphotodynamic therapy application.

Dr. Sun is having three publicationscoming out in the February issue ofApplied Physics Letters, and Januaryand February issue of Optics Commu-nications, 2003.

Wenfang Sun’s Lab

Dr. Sun, Fengqi Guo and Paul Barron.

She and postdoctoral researcherDr. Fengqi Guo attended the 2002annual ND EPSCoR conference inOctober and presented their recentresults on the synthesis and lumines-cent properties of platinum terpyridylphenylacetylide complexes. They aregoing to submit a paper on this workto Chemistry of Materials very soon.

During the winter break, Dr. Sun took acruise vacation to the Bahamas. Sheenjoyed the wonderful tropic scenery,the delicious food and fantasticshows. Now she feels refreshed andready for the spring semester.

This year the Sibi group got muchlarger - 15 in total! We welcomedone grad student, and five post-docs.

Graduate student RajeshSubramanian is from India.

The new post-docs who joined ourgroup this year are Dr. PrabagaranNurayansay, also from India, Dr.Goran Petrovic from Yugoslavia,Dr Liwen He, Dr Xiaoping Nie andDr. Max from China.

Two of our grad students graduatedfinally and have taken up positionsin Chicago and Raleigh, N.C., Mei(Methyl Iodide) Liu (Abbott) andTara Rheault (GSK).

Most of you must have enjoyedthe movies Dr. Cook made forthem. If not, you can rent them inselect Blockbuster locations inFargo!

Mona went to her home country,Norway, after a long time for agrand re-union!

Guorong Sun went home to Chinaduring Christmas and came backwith a wedding ring on his finger!

Hirofumi Matsunaga will beleaving our group around April togo back as an assistant professorin Japan.

Sandeep Ghorpe is getting marriedin April, and is preparing for histravel to India in March. BonVoyage for him!

Doctor in waiting Shankar Manyemis busy writing a review for Chemi-cal Reviews.

Jake Zimmerman’s paper will besubmitted to JACS soon.

Most of the group will be in ‘post-Mardi Gras’ New Orleans for theAmerican Chemical Societymeeting.

News fromSibi Group

Three new people have joined theHamilton group. Sophomore KarenBeckman began working in the groupin August. Graduate student JasonRolfstad and freshman URM studentDave Schultz both joined in December.Karen and Jason are working ondeveloping multinuclear rutheniumcompounds for use as drugs to treatseptic shock, while Dave’s projectinvolves the coordination chemistry of

the antibiotic D-cycloserine withvarious first two transition metals.Second year graduate student NicolePoppinga continues her work on metalremoval from the iron transport proteintransferrin. Sophomores Darla Powelland Evan Erickson are investigatingthe interactions of ruthenium chemo-therapeutic agents with transferrin.

The Hamilton Lab

By: Dr. Wenfang Sun

By: Dr. Rajesh Subramaniam

By: Dr. David Hamilton

Chem-News 8 February 2003

May 31 - June 1, 2003 North Dakota State University Fargo, ND

Speakers (tentative list)

Amy Sang Danny Welch Florida State University University of Alabama-Birmingham

Gary Rosenberg Maury Goodman University of New Mexico University of California-San Diego

Gene Homandberg Tudor Oprea University of North Dakota Univ. New Mexico School of Medicine

Victor Hruby Yuan-Ping-Pong University of Arizona Mayo Clinic

Contact Information Chair Center for Protease Research Dr. Mukund P. Sibi Department of Chemistry Center for Protease Research North Dakota State University Phone: (701) 231-8251 Fargo, ND 58105-5516 Fax: (701) 231-1057 Phone: (701) 231-6114 E-mail: Mukund.Sibi@ndsu.nodak.edu E-mail: Libby.Wasserbeck@ndsu.nodak.edu

Research Contributions : All participatnts are encouraged to contribute a Poster, some of which will be selected on site for an oral presentation.

Rasmussen Group

This fall has been very eventful for theRasmussen Group. In September, graduatestudent Don Kenning presented his miniproposals. He is now developing his maxiproposal and hopes to defend it in the nearfuture.

In mid-December, the group published anote in the Journal of Organic Chemistry onthe synthesis and reactivity of thieno[3,4-b]pyrazines. In addition to graduate studentDon Kenning, undergraduates Kari Mitchell,Tessa Calhoun, Melanie Funfar, and DanielSattler were contributing co-authors to thiswork.

Two more papers, one from theaminothiophene project and one from thethienopyrazine project, have also beensubmitted to the Journal of the AmericanChemical Society.

By: Don D. Kenning The Rasmussen Group is continuing togrow. In December, former undergradu-ate Misty Tomchuk joined the Group asa graduate student and freshmenKenneth Anderson and Curtiss Kovashjoined the Group under the Undergradu-ate Research Mentorship program.They should be great additions to theunique character of the Group.

For the holidays, the Group got togetherat Dr. Rasmussen’s house for a Christ-mas party and exchanged gifts. Agood time was had by all.

Also over the holidays, former Groupmember Kari Mitchell became engagedto Chris McGee. We heartily congratu-late them and wish them the best ofluck for the future. Kari is currentlypursuing a Ph.D. at the University ofMinnesota – Twin Cities.

Since the fall of 1995 semester,the Chemistry Department hasoffered a series of weekly helpsessions for students takingChemistry classes.

The voluntary program givesstudents a chance to meet withother members of their class,compare notes, discuss importantconcepts and develop strategiesfor studying chemistry.

Greg Oswald coordinates theprogram. His chemistry SI staff:

Chemistry 117 Greg RohdeChemistry 121 Krista FisherChemistry 122 Amy Richter,

Dan KeysChem 341, 342 Penny Neisen

Some of the SI staff function asteaching lab assistants.

Present Enrollements:

Gen Chem121 lecture 389

Gen Chem122-1 200

Gen Chem122-2 397

Organ Chem 342-1 225

Organ Chem342-2 19

General Chemistry 121 Labs 280 students

General Chemistry 122 Labs 200 students

Organic Chemistry 341Labs 80 students

Organic Chemistry 342 Labs 60 students

Fargo Conference on Metalloproteinases 2003

SupplementalInstruction

Chem-News 9 February 2003

35th Great Lakes Regional Meeting

May 31 - June 2, 2003 Chicago

ton American Chemical Society News

Preliminary Calendar of Events

1/13/03 Call for papers Opens3/3/02 Registration Opens3/17/03 Deadline for papers5/12/03 Deadline/early registration5/31/03 Meeting starts

Friday, May 30, 2003 6:00 pmGibbs Medal Award to Prof. JohnBrauman of Stanford University

Saturday, May 31, 2003Awards Luncheon

Saturday, May 31, 2003EveningPoster Session/Reception

Sunday, June 1, 2003EveningPoster Session/Reception

Monday, June 2, 2003Grant Writing Workshop

Women’s LuncheonDr. Marian Thurnauwer (Argonne)

At:Loyola University of ChicagoLake Shore Campus6525 North Sheridan RoadChicago, Illinois

www.membership.acs.org

What is the Cook Group you ask?Better start at the top. The bosshimself, Dr. Greg Cook is in charge oftwo postdocs, four graduate studentsand two undergraduates—better knownas “The Cookies” and all of which maketheir home away from home in a littlecorner of third floor Dunbar Hall.

First are our postdocs. Dr. EthirajanManivannan hails from Chennai, Indiaand is currently working on thesynthesis of phosphinate andoxazoline based inhibitors of matrixmetalloproteinases (MMP).

Dr. Liangdong Sun comes fromLanzhou, China and works on naturalproduct synthesis and new palladiumand indium catalyzed reactions.

On to the graduate students. RobertKargbo comes from Freetown, SierraLeone. His project involves studying

the combination of palladium andindium to control the formation ofnew carbon-carbon bonds withimines.

Xiaomin Jin, from Zhejiang, China,is involved in the synthesis of MMPinhibitors.

Jason Smart, somewhat local fromRedwood Falls, Minnesota, works onthe synthesis of heterocyclic MMPinhibitors.

Finally, a bittersweet day in theCook Group. The senior member,Jason Hallman, successfullydefended his master’s thesis inDecember and is on track to earninghis Master of Science degree. Thegroup will miss him, but we wish himwell working North Carolina—we’reproud of you, Jason!

What’s Cooking in theCook Group?

By: Brandon Gustafson

Now, we are left with the undergraduates. First is Jessica Gorehamfrom Fargo. Jessica works withManivannan on synthesizingphosphinate MMP inhibitors.

Brandon Gustafson, from the distantland of West Fargo, rounds out thegroup. His work picks up whereprevious graduate students left off—studying the mechanism of atomtransfer cyclizations using catalyticamounts of In(I) and In(III) salts.

Basically, the Cook Group spends theirtime doing their part of the COBREProject and studying the behavior ofindium and palladium.

If you are looking for more info, or youjust want a place to hang out, look usup at:

www.ndsu.nodak.edu/instruct/grcook/group

Dr.

Man

ivan

nan

Chem-News 10 February 2003

Libby Wasserbeck joined the Centerfor Protease Research in August.

Libby says, “I’m from Newcastle, OK.Sooner born and Sooner bred.”

“I graduated from the University ofOklahoma with a B.A. in Sociologyand a minor in Business and on awhim decided to move to Fargo, ND.I worked for Lake Agassiz RegionalLibrary before coming to NDSU.”

“ In my spare time, I serve as editoron the board of Woman of Today, acommunity service organization. Ienjoy backpacking, camping, andhope to try cross-country skiing thiswinter! I also love to travel.”

Center for Protease Researchwww.ndsu.nodak.edu/cobre

Chem-News is published by

Department of ChemistryNorth Dakota State University

PO Box 5516Fargo, ND 58105

www.chem.ndsu.nodak.edu

Rose Overby, EditorDr. John Hershberger, Chairman

To obtain a copy or submit comments:e-mail:

R.Overby@ndsu.nodak.edu

New Enrollment RecordFor the first time, NDSU’s fall enroll-ment topped 11,000 students. Officialthird-week numbers announced are11,146 compared to 10,538 last year.

“Since 1997, we have increased by1,644 students. This represents oneof the most dramatic periods ofenrollment growth in the institution’shistory,” said George Wallman, vicepresident for student affairs.

DatesSummer 2003 OrientationJune 12-13 Honor’s OrientationThis session is designed for studentswho have an ACT score of 31+ and arereceiving Presidential or National MeritScholarships as well as those acceptedinto the University Honor’s Program.

June 23 Transfer Orientation (1 day)June 24-25 Freshman/Family (overnight)June 25-26 Freshman/Family (overnight)June 26-27 Freshman/Family (overnight)July 8 Freshman/Family (1 day session)July 9 Freshman/Family (1 day session)July 10 Freshma/Family (1 day ession)

For more information: (701)231-8379

The McNair Scholars Program

Robert Kargbo, at the McNair event presenta-tions on December 12, 2002. Robert is thefourth McNair Scholar to complete the programunder the mentorship of Professor Greg Cook.

Chemistry Activities

Dr. Melvin Morris, Professor Emeritus, continuesto offer “Free Tutoring” every day in theChemistry Department and is very popularespecially near exam time.

Chemistry DepartmentOffers Free Tutoring

New COBRE Staff

NDSU students who have completedtheir sophomore year in approvedacademic disciplines may apply.Participants are selected on the basisof having the greatest potential forpursuing doctoral studies.

Once a candidate is accepted in theprogram, a faculty mentor is chosenby the student in consultation with thedirector. In addition, a library mentoris selected to help McNair Scholarsprepare research materials for theirsenior project.

Students participating in the programreceive stipends of up to $2,800 percalendar year. Additional funds areavailable for travel to professionalconventions.

http://www.ndsu.edu/trio/msp/msp.html

Mary Hinschberger joined the ChemistryDepartment part-time this fall to help with ourgraduate recruiting efforts. Mary recentlyobtained her bachelor’s degree in sociology andremains with the departmet while pursuing aMaster’s degree.

Chem-News 11 February 2003

Governor’s School

April 26, 2003

North Dakota State University, Bison Sports Arena is thesite for the Science Olympiad. The events are forDivision C schools (grades 9-12 and Division B Schools(grades 6-9) and run from 9 am - 3 pm.

www.ndsu.nodak.edu/csme/olympiad

This summer we will do a pilot project with Fine Arts onthe NDSU campus and Trollwood Performing Arts toinvite additional students to our campus.

Governor’s Schools are nation wide with many stateshaving more than one and in many cases at multiplesites.

This will be our 14th summer at NDSU adding enrichmentto the many educational experiences of North Dakotahigh school sophomores and juniors.

http://govsch.ndsu.nodak.edu/gs98.html

June 8 - July 19

North Dakota StateScience & Engineering Fair

The Southeastern ND Regional Science and EngineeringFair, sponsored by North Dakota State University andSociety of Automotice Engineers will be held onApril 3, 4, 2003 at the Benson-Bunker Fieldhouse atNorth Dakota State University. The territory includes thecounties of Griggs, Steele, Barnes, Cass, Ransom,Richland and Sargent.

***

April 3, 4, 2003

NDSU Labs

***

***

Dr. Inder Seghdal,COBRE Principle

Investigator,Pharmacy, at work

with students.

Mallik Lab, Chemistry: Dr. Sanku Mallik with Benita Chandra. Sibi Lab, Chemistry: Rajesh Subramanian, Dr. Max and Jake Zimmerman.

News from Chemistry Club

North Dakota State University Chemistry Department P. O. Box 5516 Fargo, ND 58105-5516

Non-Profit OrgU. S. Postage Paid

Permit No. 818Fargo, ND 58105

By Karla Radke

Members of the Chemistry Club have been busy this fallwith the upcoming National ACS meeting in mind.

Many days were spent by Chemistry Club membersworking concession stands at FargoDome events. TheFargoDome football games and concerts are a great wayto earn money for traveling to the National ACS meetingand who doesn’t love a free hot dog at the end of yourshift? Yeah, me neither.

Anyway... we also did demonstrations for kids at YunkerFarm, hoping to inspire the little minds who came by themedical exhibit.

Finally, we publicized National Chemistry Week in Octoberby having an information booth in the Memorial Union andpublishing ads in the The Spectrum and The Forum.

Demonstrations by the Chemistry Club at local elementaryschools will take place in December and January. Thestudents will learn about candy chromatography, chemilu-minescence, a hands-on-activity for making “Gak,” andother exciting experiments.

Chemistry Club Members:Jess Augdahl, Derek, Hall, ScottRothstein, Mandy Zimmerli, SandiHagen, and Karla Radke.