UCL INSTITUTE OF CHILD HEALTH

Clinical and Molecular Genetics Unit, ICHand

Department of Chemical Pathology, GOSH

PROFESSOR OF CLINICAL CHEMISTRY

Job Ref. KW/08/60

UCL Institute of Child Health UCL Institute of Child Health in30 Guilford Street,  London WC1N 1EH partnership with Great Ormond Street Tel:  +44 (0)20 7905 2742 Hospital for Children NHS rust Fax:  +44 (0)20 7405 6917 The child first and always

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UNIVERSITY COLLEGE LONDON

INTRODUCTION

UCL is one of the UK’s premier universities. It is a world-class research and teaching institution based in London whose staff and former students have included 19 Nobel Prize winners. Founded in 1826, it was the only university in England at that time which admitted students regardless of race or religion. UCL was also the first to admit women on equal terms with men. Today UCL is a friendly university in which to work and study and it continues to thrive on the diversity and creativity of its community.

UCL is in practice a university in its own right, although constitutionally a college within the federal University of London. With an annual turnover exceeding £450 million, it is financially and managerially independent of the University of London.

The UCL community

UCL currently employs approximately 8,000 staff and includes academic units as diverse as the Slade School of Fine Art, the Bartlett School of Architecture and the Institute of Child Health (in which this post is based) which is associated with Great Ormond Street Hospital. In total, there are 70 Academic Departments and Institutes whose activities span the following: arts and humanities, social and historical sciences, law, architecture and the built environment, engineering, mathematical and physical sciences, life and clinical sciences, and medicine. UCL’s academic and research staff are a truly international community with more than a quarter coming from 84 countries outside the UK.

12,000 undergraduates and 7,000 graduate students study at UCL, of whom over 25% come from 130 countries outside the UK. UCL offers 275 undergraduate programmes and more than 220 taught postgraduate programmes as well as the opportunity to carry out postgraduate research in all of its subjects.

Quality of UCL’s teaching and research

Two measures of the current quality of UCL’s teaching and research are the results of the external teaching quality assessment reviews and the periodic Research Assessment Exercise (RAE).

During the teaching quality reviews conducted in the period 1993-2001, 75% of all reviews of UCL Departments resulted in ratings of ‘excellent’ (22+ points out of 24). Of these, four Departments received the maximum 24 points.

In the 2001 RAE, 60 UCL Departments achieved top ratings of 5* and 5: of these, 15 Departments have since been classified by the Higher Education Funding Council for England (HEFCE) as 'best 5*' for HEFCE research funding purposes - that is, departments which either received the 5* rating both in 2001 and in the previous RAE in 1996 or which improved their 1996 rating to 5* in 2001 while maintaining or increasing numbers of research active staff. These 'best 5*' departments span the full range of UCL’s disciplines.

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Another measure of UCL’s research excellence has been its success in bidding for external competitive funds from the Joint Infrastructure Fund (JIF) and the Science Research Investment Fund (SRIF). With the addition of required matching funds, JIF and SRIF are allowing UCL to invest more than £250 million into state-of-the-art infrastructure for cutting-edge research and teaching programmes.

UCL is consistently rated among the top four universities in the UK (together with Cambridge, Imperial College and Oxford) and in the 20 best universities in the world.

UCL Institute of Child Health and Great Ormond Street Hospital for Children NHS Trust

The UCL Institute of Child Health (ICH) forms part of the Faculty of Biomedical at University College London (UCL). ICH has maintained a particularly close relationship with Great Ormond Street Hospital for Children NHS Trust (GOSH) throughout its fifty-five year existence. These close links have enabled ICH to pursue medical research in the context of child health and disease, based upon an integrated approach of careful clinical observation and scientific investigation. This allows an understanding of the underlying mechanisms and, in turn, leads to precise diagnosis and development of new therapies. The Institute’s current academic structure consists of seven research themes:

CancerCardiorespiratory SciencesGenes, Development and DiseaseInfection and ImmunityNeurosciences and Mental HealthNutritional and Surgical SciencesPopulation Health Sciences

GOSH is a post-graduate teaching hospital, linked with the Institute of Child Health. Founded by Dr Charles West in 1852, Great Ormond Street Hospital was the country’s first hospital for children. Now one of the world’s leading children’s hospitals, the ward facilities consist of 357 beds. These beds are arranged in 26 wards including 33 intensive care beds (PICU, ICU and CICU), 8 high dependency and 5 transitional care beds. There are 8 operating theatres in use performing over 11,000 operations per year. The patient population consists of 22,000 inpatients per annum including 8,200 day cases (35% of inpatient activity). Some 84,000 outpatients attend the hospital annually and in addition there are over 600 outreach clinics per year. Referrals come from all over the UK and also abroad. With 32 clinical and surgical specialities, Great Ormond Street offers the widest range of paediatric expertise under one roof. The Trust employs a total of 2,600 staff. The Trust is in Partnership with North Middlesex University Hospital Trust and Haringey Primary Care Trust.

Examples of external recognition for the joint working at ICH and GOSH include the maximum Grade 5*A that was awarded to ICH in the 2001 HEFCE Research Assessment Exercise, one of only four in clinical sciences, and the “excellent” rating (score of 23/24) given in 2002 by the Quality Assurance Agency for ICH’s taught programmes. During 2005, all 22 programmes of Research and Development submitted to the Department of Health, under its Priorities and Needs Funding

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stream, were scored as “strong” (categories: strong, moderate, weak). In 2006, the partnership between Great Ormond Street Hospital for Children and the Institute of Child Health was awarded Specialist Biomedical Centre Status, under the government’s National Institute for Health Research initiative. This is the only biomedical centre devoted to children’s health, and confirms ICH and GOSH as the UK’s leading centre for research, education and service delivery in children’s medicine.

BACKGROUND TO THE POST This professorial position has been created by the bringing together of a vacant Chair of Chemical Pathology at ICH (now re-designated Chair of Clinical Chemistry), and a vacant Consultant Clinical Scientist post (Band 9) at GOSH. The aims of the position are:

(i) To provide academic leadership and innovative research in clinical chemistry as applied to childhood conditions, their diagnosis and early detection. The appointee will be a Professor within the Clinical & Molecular Genetics Unit at ICH, in which related academic staff in biochemical and metabolic paediatrics, as well as in clinical genetics, molecular genetics and endocrinology, are currently located;

(ii) To provide leadership for the development of the enzyme and metabolic clinical service within the Department of Chemical Pathology, GOSH. This department has much potential for expansion in diversity and volume of work, supported by a committed team of scientific staff and with close links with the metabolic and other physicians within GOSH.

A particular aim is that the appointee should develop laboratory-based clinical chemistry as an academic discipline of excellence at ICH. There has been little academic activity in this area for two decades, although there is a rich source of clinical and population material available for research through the services provided by GOSH. This professorial appointment is part of a renewed effort to develop further academic activity at ICH/GOSH in metabolic and biochemical paediatrics. The appointee will be expected to work closely with established academics in metabolic paediatrics, proteomics, genetics, nutrition and epidemiology to make full use of the rich clinical and biological material available and to generate new academically valuable and clinically-relevant research programmes. With the introduction of translational research funding via the National Institute for Health Research, it is expected that the appointee will be active in securing research funding for projects in applied paediatric clinical chemistry. Further translational opportunities are afforded by the location of the North London Newborn Screening Laboratory within the Department of Chemical Pathology at GOSH- the largest newborn screening laboratory in the UK – and the UK Newborn Screening Programme Centre (http://www.newbornscreening-bloodspot.org.uk/) at GOSH.

The appointee will have clinical responsibility for the Enzyme Laboratory, and will be expected to provide a strong lead in modernising and developing the laboratory service.

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Clinical and Molecular Genetics Unit, ICH

Genetics is a particular strength within ICH’s research portfolio, and encompasses clinical genetics and dysmorphology, together with laboratory-based molecular genetics. Included within the Unit are sub-groups of Metabolism & Proteomics, and Paediatric Endocrinology.

Senior members of the Clinical and Molecular Genetics Unit are: Professor Gudrun Moore – Head of Unit; Molecular Genetics of ImprintingProfessor Raoul Hennekam – Clinical Genetics and DysmorphologyProfessor Peter Clayton – Metabolic PaediatricsProfessor Mehul Dattani – Paediatric EndocrinologyProfessor Peter Hindmarsh – Paediatric EndocrinologyDr Maria Bitner-Glindzicz – Clinical and Molecular Genetics of Hearing DisordersDr Lyn Chitty – Fetal Medicine and Clinical Genetics

Senior staff in related areas of ICH include: Professor Andrew Copp – Director of ICHProfessor David Goldblatt – Director of Clinical R&DProfessor John Deanfield – Theme Leader for Cardiorespiratory SciencesProfessor Pete Scambler – Theme Leader for Genes, Development and DiseaseProfessor Christine Kinnon – Theme Leader for Infection and ImmunityProfessor Francesco Muntoni – Theme Leader for Neurosciences and Mental HealthProfessor Alan Lucas – Theme Leader for Nutrition, Metabolism & Surgical SciencesProfessor Carol Dezateux – Theme Leader for Population Health Sciences

The new Professor will have the opportunity to link with a wide variety of research areas, as represented by the current research strengths at ICH (see http://www.ich.ucl.ac.uk/ich/academicunits).

The following ICH facilities may be of particular interest:

Proteomics and mass spectrometry Affymetrix microarray service DNA diagnostics and cytogenetics (in conjunction with GOSH Departments) Automated DNA sequencing (including Illumina platform) Fluorescence-activated cell sorting Confocal microscopy Human Developmental Biology Resource (national resource providing human

fetal material for gene expression studies) Gene targeting service (ES cell transfection and chimera production) Transgenic breeding and re-derivation facility

Chemical Pathology Department, GOSH

The Chemical Pathology Department is part of the GOSH Pathology Unit, which also includes Haematology, Histopathology, Immunology, Microbiology and Paediatric Cyto-Malignancy Unit. The Pathology Unit is part of Diagnostic and Therapeutic Services. Chemical Pathology holds full CPA accreditation and is divided into 4 sections: Routine, Metabolic, Enzymes and Newborn Screening. Each area is led by

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a Principal Clinical Scientist and Biomedical Scientist 3, resulting in strong scientific expertise in all areas.

Senior Staff in GOSH Pathology are:

Dr Marian Malone – Pathology Service Unit ChairDr Catherine Cale – Head of Chemical Pathology Dept and Newborn ScreeningDr Steve Krywawych – Head of Metabolic LaboratoryMs Anne Sheldrake – Laboratory Manager for Chemical Pathology

Enzyme Laboratory, GOSHThe Professor will have clinical responsibility for the Enzyme Laboratory, which has a staff comprising: 4 BMS posts (1 band 8a, 1 band 7, 2 band 6) supported by 2 MLAs and 2 MTOs. A band 7 Clinical Scientist is dedicated to this service, and the band 8a Principal Clinical Scientist post in Newborn Screening (currently being recruited to) will have some input into this area.

The Enzyme Laboratory provides a service which is mainly for the investigation of lysosomal storage disorders. It attracts a significant volume of external work (at least 50%) and has a national and international reputation. It hosts an NCG funded service for monitoring lysosomal enzyme therapies.

Annually, the Enzyme Laboratory handles approximately 3000 specimens on which are performed approximately 6500 enzyme tests. This service provision comprises a wide range of enzymes involving different areas of metabolism and representing a variety of cellular organelles. The overall list of enzymes includes a comprehensive range of lysosomal enzymes, those associated with glycogen metabolism, galactose metabolism, fructose metabolism, the urea cycle and several connected with amino acid metabolism. A variety of tissues are employed for analysis which is dependent upon the enzyme investigation. For the major of these different enzyme assays, a prenatal diagnostic service is also available.

The laboratory benefits from close integration with the rest of the Chemical Pathology department (in particular metabolic) and with clinical colleagues. Senior members of the Enzyme Laboratory attend the weekly Metabolic Meeting in ICH and there is a fortnightly MDT attended by the Clinical Scientist and senior BMS staff from the Enzyme Laboratory, the consultant clinical metabolic team, Dr Steve Krywawych, members of the Histopathology Department and members of the Clinical Molecular Genetics Department.

The Enzyme Laboratory is currently situated within ICH, but is due to move into an area of the Camelia Botnar Laboratories (CBL) adjacent to the rest of Chemical Pathology when Molecular Genetics relocates during 2009. The CBL is a purpose built laboratory building (opened 1996) providing modern accommodation to all the Pathology departments.

REPORTING CHAIN

Academic responsibility is to the Head of the Clinical Genetics Unit (currently Professor Gudrun Moore), and thence to the Director of ICH (currently Professor

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Andrew Copp). Clinical responsibility is to Dr Catherine Cale, Head of Chemical Pathology Department, GOSH.

JOB SPECIFICATION

The appointee will be trained to PhD level, and have a strong track record of translational research in clinical chemistry. This will include the publication of original papers in high impact journals, the securing of grants from peer-reviewed funding bodies and the supervision of students for higher degrees. In addition, the appointee must be a state-registered Clinical Scientist, with previous record of excellence and achievement in the running of a forward-looking and successful NHS laboratory service in clinical chemistry. Duties of the post will include:

AcademicThe post-holder will be expected to develop an independent and original research programme in basic or clinical science that relates to the pathogenesis and diagnosis of inborn errors of metabolism, in particular neuro-metabolic disorders. The research programme should be relevant and complementary to existing research activities in chemical pathology, metabolic paediatrics, proteomics and other related areas of ICH and GOSH. As part of this research activity, the Professor is expected to:

Secure external grants from peer-reviewed funding bodies Publish original research and review articles in high impact journals Supervise postgraduate students to higher degrees

The appointee will be expected to engender a spirit of cooperation and collaboration in clinical chemistry and metabolic research at ICH and GOSH. He/she will be responsible for co-ordinating research across Chemical Pathology, facilitating studies with clinical teams, and developing translational interfaces between basic science research at ICH and other research activities, including GOSH-based clinical and newborn screening research, as well as ICH-based population-based research. The appointee will be expected to provide line management (including regular appraisal) to members of his/her own research team, and to promote the career development of staff under his/her line management.

The Professor’s research should incorporate a commitment to the principles of Research Governance. He/she will be expected to carry out any additional duties as may reasonably be required within the general scope and level of the post as agreed with the Unit Head and/or ICH Director.

ClinicalThe appointee will be expected to provide a high level of personal scientific skill and expertise in the full range of routine and specialised investigations and procedures in the Enzyme Laboratory, with additional input to the metabolic and other services where expertise and need arises. He/she will be expected to take a lead on assay development and modernisation within the Enzyme Laboratory to ensure that a comprehensive, efficient and cost effective service is provided.

He/she will provide strong leadership within the Enzyme Laboratory, providing training to other staff in the interpretation and authorisation of results in relevant areas and will receive and interpret results of investigations, and communicate

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results to requesters and users of the service. He/she will attend relevant ward rounds and multidisciplinary meetings and provide a high standard of clinical liaison.

The successful applicant will ensure the rational and appropriate use of tests by requesting clinicians, provide an expert consultation service for internal and external users in relevant areas and ensure that a prenatal diagnostic service can be maintained.

The appointee will be expected to ensure that the department participates in external quality assurance, has in place the necessary internal quality assurance procedures and that standards of work and procedures and policies are commensurate with maintenance of accreditation with CPA UK Ltd (or other relevant bodies). He/she will provide training to junior staff members, and also visiting scientific and medical staff.

The appointee will plan strategically for the provision of diagnostic services congruent with the needs of users, other sections in Chemical Pathology, the other pathology departments and the Trust. He/she will be expected to develop an active programme for new assays, methodologies and technologies to ensure the provision of an efficient and forward looking service. He/she will lead on the development of a programme of rationalisation and modernisation within the laboratory and assist with the management of the Chemical Pathology service where required, including budgetary management.

The appointee will be accountable for the effective organisation, staffing and appropriate skill mix of the service. He/she will be responsible for general staff management duties within the enzyme laboratory as required, including appraisals, interviews and disciplinary and other procedures and will collaborate with the Head of Department and Service Unit Chair in the preparation and implementation of service plans and policies.

PERSON SPECIFICATION

Requirements Essential DesirableQualifications/Training PhD

FRCPath

HPC registration (Clinical Scientist)

Knowledge/Previous Experience

Develops and delivers the strategy of the teams/departments

A strong track record of translational research in clinical chemistry

Supervision of students for higher degrees

Experience of leading and directing a successful research team.

Experience of working in multidisciplinary or interdisciplinary research teams and/or environments

Knowledge of, and experience

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High level of knowledge in interpretation of enzymatic and metabolic diagnostic tests

CPA/HTA and other regulatory and accrediting frameworks

Specialist expertise in techniques and methodologies in Enzyme and Metabolic Chemical Pathology

Ability to take full and independent clinical responsibility

Heading an NHS laboratory service.

Understanding of budgetary and staff management

in refining, high throughput technologies such as tandem mass spectrometry for novel diagnostic and screening applications

Awareness of, or contribution to, strategic debates relevant to diagnostic technologies and biomarker research and development

Experience of working with industry to support introduction of innovative diagnostic tests into the translational pipeline

Previous TrainingManagement/Audit

Training in research methodology gained through postdoctoral experience in high quality research organisations

Active participation in Clinical Audit

Recruits and manages individuals effectively to create a high performing team

Provides leadership, direction and feedback on team and individual objectives

Management training

Academic AchievementsResearch/Publications

Extensive track record of publications in high quality peer-reviewed scientific and clinical journals

Active clinical chemistry research profile at international level with a continuing track record of external research grant funding

Research programme that complements existing research strengths at ICH/GOSH

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SkillsLeadership skills

Organisation skills

Communication skills (verbal and written)

Ability to supervise and mentor junior colleagues in clinical and research work and participate in the organisation of an academic unit

Ability to interact on a daily basis with laboratory scientific staff and to work as part of a team

Maintains an awareness of the wider context (UCL wide, national and international as appropriate) and responds accordingly

Provides leadership, direction and feedback on team and individual objectives

Ability to provide a smooth and efficient specialist Pathology Service

Excellent communication skills, both verbal and written

Good teaching and presentation skills

Teaching Active participation and commitment to teaching at postgraduate level particularly the supervision of research students (PhD and MD)

Promotes excellence in areas of teaching, research, administration and the provision of support services

Ensures regular review of teaching, research, knowledge transfer, enabling and support activities to maximise effectiveness and impact

Training in teaching methods and experience of teaching courses at undergraduate and/or postgraduate level

Other Requirements Accountability - takes responsibility for own actions and promotes good team working

Computer literate

Awareness of the broader HE and NHS issues and the

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Openness - shares information and good practice appropriately

Mutual respect - treats others with courtesy and respect at all times

The highest ethical and professional standards in research, education and clinical practice and a flexible attitude to collegiate working

Involvement in continuing professional development

Commitment to implementation of the Principles of Research Governance

Promotes UCL’s values and corporate objectives to colleagues and externally to UCL

Demonstrates a commitment to (and promotes) equality and diversity ensuring UCL is an inclusive environment in which individuals are respected and unacceptable behaviours challenged

possible implications for the Unit/Theme

Involvement in professional activities external to the workplace

Training in interview and recruitment skills

The following links to the Competency expectations of post holders with management responsibilities.

http://www.ucl.ac.uk/hr/competencies/UCLManagementCompetencies.doc

TERMS AND CONDITIONS OF EMPLOYMENTThe appointment will be made in accordance with UCL’s Statutes and Regulations for Professors, Readers and Teachers. Further details are available in the Academic Staff Handbook provided by UCL (available on request). All appointments are subject to the receipt of references satisfactory to ICH and UCL.

Starting DatePost is available immediately but the actual start date will be negotiated with the Director of ICH and Head of Chemical Pathology, GOSH, to ensure continuity of the appointee’s research

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Salary Salary to be negotiated with the Director of ICH, in line with current practice for non-clinical professors at UCL.

In addition, London Weighting of £2,649 per annum is payable. Salaries are paid monthly in arrears by direct transfer to your bank account.

Progression through the salary scale is incremental and will take place on 1st August each year. Cost of living pay awards are negotiated nationally and are normally effective from 1st August each year.

SuperannuationThe successful applicant will be eligible to join the Universities Superannuation Scheme (USS) which is a final salary scheme or to remain in the NHS Scheme if he/she is already a member and wishes to continue in that scheme.

Hours of WorkThere are no fixed number of hours of work for Academic staff. However, a notional working week of 36.5 hours is used to assist in workload planning and calculations related to salary.

Time will be made available to attend meetings etc for the purposes of Continuing Professional Development (CPD).

Annual Leave

The leave year runs from 1 October to 30 September. Staff are entitled to 27 days annual leave per year (pro rata for part-time staff). Time off in lieu of additional hours worked may be taken in addition to annual leave, as agreed with the Head of Department

Staff are also entitled to 8 public and statutory holidays, and additional days (normally 6 per year) on which UCL is closed. Part-time staff will be entitled to the pro-rata equivalent of these days.

Relocation ExpensesUCL has a policy for the reimbursement of relocation expenses for general funded posts i.e. posts not funded from external sources – further information can be found at: http://www.ucl.ac.uk/hr/docs/relocation_expenses.php

Sabbatical LeaveAcademic staff who have completed probation are entitled to apply for sabbatical leave for one term in every three years.

Sick Leave

  Full Pay Half Pay

During first 3 months service 2 weeks 2 weeks

3 months service or more but less than 12 months service

9 weeks 9 weeks

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12 months service or more but less than 3 years service

13 weeks 13 weeks

3 years service or more but less than 4 years service

22 weeks 22 weeks

Service of 4 years or more 26 weeks 26 weeks

Retirement AgeThe normal date of retirement is 30th September in the session in which the member of staff reaches the age of 65.

Annual Season TicketUCL has an interest-free loan scheme to enable staff, to purchase annual season tickets, the cost being deducted from salary in ten equal monthly instalments.

Period of NoticeEmployees must give a minimum of 3 months notice in writing.

Staffs with teaching or other responsibilities for students are required to give notice such that they leave at the end of a term.

Rehabilitation of Offenders Act and Protection of ChildrenDue to the nature of this post it is exempt from Section 4(2) of the Rehabilitation of Offenders Act (1974) by virtue of the Rehabilitation of Offenders Act (Exemption Order 1975). Applicants are, therefore, not entitled to withhold information about convictions including those which for other purposes are "spent" under the provisions of the Act. In the event of employment, any failure to disclose such convictions could result in dismissal or disciplinary action by UCL. Any information given will be completely confidential and will be considered only in relation to application for positions to which the order applies.

In addition, ICH is entitled under arrangements introduced for the protection of children to check with the police for the existence of any criminal record of the successful applicant and to check the Protection of Children List. Information received by the police will be kept in strict confidence and will be destroyed immediately the selection process is completed. Any offer of employment is therefore subject to satisfactory clearance being received from the Criminal Records Bureau.

The disclosure of a criminal record or other information will not debar you from appointment unless the selection panel considers that the conviction renders you unsuitable for appointment. In making the decision, ICH will consider the nature of the offence, how long ago it took place, and at what age you were when it was committed along with any other factors which may be relevant, including appropriate considerations in relation to UCL’s Equal Opportunities Policy.

Failure to declare a conviction, caution or bind-over may, however, disqualify you from appointment or result in summary / disciplinary action if the discrepancy comes to light. If you would like to discuss this issue in confidence, please contact Ms Clare Speary, Human Resources Administrative Officer, on 020 7905 2650.

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Recruitment and selectionAll employees who are responsible for recruiting new staff are required to attend an in-house recruitment and selection training course before they can be involved in the recruitment process.

Research GovernanceThe postholder will be expected to be familiar with the requirements of the ICH/GOSH research governance framework and to comply with all ICH/GOSH policies pertaining to research governance. This will include ensuring that all clinical research activities of the postholder are approved by the Trust and an appropriate ethics committee before commencement. This will also include meeting all the Trust research audit, monitoring and training requirements.

The ICH/GOSH research governance framework can be found on the ICH website at:http://www.gosh.nhs.uk/ich/r&d/r&d.htm but it should be noted that the guidance is subject to change as the framework is implemented.

Data ProtectionUCL and the GOSH Trust are required by law to comply with the Data Protection Act, 1998. It is the commitment of UCL to ensure that every current employee and registered student complies with this Act to ensure the confidentiality of any personal data held by UCL, in whatever medium, through its Data Protection Policy.

Employees are authorised, if required to do so, to obtain, process and/or use personal information whether held on a computer or on manual paper files in a fair and lawful way and in accordance with data subjects’ rights. Data should be held only for the specific registered purpose and not disclosed in anyway incompatible with such purpose. It should be adequate, relevant and not excessive, accurate and where necessary up to date and kept for no longer than necessary. It should only be disclosed to authorised organisations as instructed and should not be transferred without adequate protection.

UCL, GOSH Trust, and all staff or others who process or use any personal information must ensure that they follow these principles at all times.

Health and SafetyEmployees must be aware of the responsibilities placed on them under the Health and Safety at Work Act (1974) and Fire Regulations, to ensure that agreed safety procedures are carried out to maintain a safe environment for employees, patients and visitors. UCL and the Trust both operate a No Smoking Policy, which does not allow smoking at work other than in a designated area.

‘No Smoking’ and ‘No Alcohol ‘PolicyIn the interest of community health, all GOSH buildings have been designated as no-smoking areas. The Trust prohibits the consumption of drugs and alcohol on Trust property and or during working hours, unless specifically sanctioned by an authorised Trust officer, and will not tolerate the use and misuse of alcohol and/or drugs in any way which impairs work performance or conduct

Confidentiality

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All UCL and UCLH employees and honorary appointees are required to exercise discretion and maintain confidentiality at all times.

In addition, the postholder will actively follow all other UCL policies which include:

Policy and Guidelines for Conflicts of InterestA Policy for Investigating and Resolving Allegations of Financial IrregularityPersonal Relationships at Work: Code of ConductPublic Interest DisclosurePolicy on the Investigation of Research MisconductFinancial RegulationsPolicy on Data ProtectionCode of Conduct for Undertaking Business on Behalf of UCL

Please see the Human Resources website http://www.ucl.ac.uk/hr/ for information on employment policies.

General Information about the UCL Institute of Child Health

ICH Refectory

Set in comfortable surroundings, the refectory offers a daily variety of hot dishes (including vegetarian), a sandwich/salad bar and other snacks and soft drinks at reasonable prices.

Training and Development

UCL is committed to the training and development of its staff. The Staff Development and Training Unit is available to offer advice, encouragement and support to staff and departments in respect of any training needs.

Full details of the courses available can be found in the Staff Development and Training Course Programme, which is available on request or by visiting the website www.ucl.ac.uk/hr/sdtu/

Library

The Friends of the Children of Great Ormond Street Library is a noted specialist paediatric collection and is the recognised main collection for paediatrics in the University of London.

The Library supports the research, teaching and clinical work of the Institute of Child Health (ICH) and Great Ormond Street Hospital for Children NHS Trust (GOSH). The Library was refurbished, redeveloped and extended in 1996, whilst a further extension was opened in November 2000. Networked PC workstations give users access to a wide range of databases and Internet resources. The collection is managed using the “Unicorn” system http://www.ion.ucl.ac.uk/admin/webcat.html

The main clinical collection comprises approximately 16,000 volumes, including bound journals, whilst over 250 current journals are received. The Library is one of the medical site libraries within UCL. Further information on the Library and Library

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services may be found at http://www.ich.ucl.ac.uk/services_and_facilities/internal/library/

The library is staffed from 9am to 6pm Mondays to Fridays.

Research and Development Office

The Research and Development (R&D) Office was set up in October 1994 to serve the joint needs of ICH and GOSH. The Office works closely with most administrative departments in the Hospital and Institute and is responsible for all research administration and implementation of the joint research strategy. There is also a close relationship with the UCL/UCLH R&D office which works in partnership with the office at ICH/GOSH. The main focus of the R&D team is to enhance performance in research and development, increase the opportunities for further funding and to maintain the level of excellence and recognition for the research that ICH and GOSH have achieved worldwide.

The current research portfolio extends to over 800 active projects covering seven research themes. The R&D Office has led the way nationally in the administration of research in the NHS and is one of the only offices in the UK to be ISO 9001 compliant. The ongoing changes to the funding of R&D make this a dynamic and challenging environment.

Information Systems Unit (ISU)

The Information Systems Unit (ISU) exists to support the IT requirements of the Institute in the areas of research, teaching and administration.

The unit supports over 1000 customers and about 2000 items of IT equipment (computers, printers etc) across seven buildings and within GOSH; support is also provided to a growing number of users based off-site.

The ISU works in liaison with colleagues within the Faculty of Biomedical Sciences (FBMS) and Information Systems at University College London (UCL IS). We are working towards streamlining our services with those of UCL IS and FBMS. There is ongoing work with the Information and Communication Technology (ICT) group at GOSH to support the interworking of IT services across ICH and GOSH.

Medical Illustration

Medical Illustration – ICH is based in Great Ormond Street Hospital and UCL Institute of Child health. It is organised into three sections:

1. Clinical Photography; dealing with photography and video recording of patients; operating theatre and post mortem room photography; pathological specimen photography and general, PR and still life photography. This section also deals with video/DVD production for in house and external clients.

2. The Reprographic Section deals with all forms of copy work including radiographs, scans, graphs, charts and tables for reproduction as prints or digital output. Also the construction and design of PowerPoint presentations.

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3. The Graphics Section produces graphic and website design, Logo and corporate ID creation, print and publication work. Output includes posters, overhead projection transparencies, booklets, brochures, stationery and digital files.

Local Amenities

In the heart of Bloomsbury, we are conveniently located between Russell Square and Holborn tube stations, served by the Central and Piccadilly lines.

Close by the Institute are numerous high street banks and a main post office.

Members of the Institute are also able to make use of UCL/ULU facilities at discounted rates, e.g. swimming pool, gymnasium, badminton, squash, exercise classes. There are also a number of cafes and bars and other facilities such as the Bloomsbury Theatre.

Informal Enquiries

Informal enquiries about the post can be discussed with Professor Andrew Copp, Director of ICH (020 7905 2189; dean@ich.ucl.ac.uk ).

For further information about the Institute of Child Health, please visit our website at www.ich.ucl.ac.uk

Submitting an application

Application for this post will be by Curriculum Vitae, Covering Letter, Appendix Form and Equal Opportunities Form (see below). Applicants must apply by email, your application MUST include a Covering Letter and CV, the application form and equal opportunities form.

Your covering letter should also include the following:

Job reference KW/08/60

1. Whether we may approach one or all of your referees prior to interview. Please note that we require details of at least two referees (to include your current/most recent employer) together with their full postal address, telephone number and email details. Relatives may not be used as referees.

2. Whether you require permission / a work permit to take up employment in the UK.

3. If employed, how many days (and how many periods) of sick leave you have had over the last 12 months (provide additional information if you feel this would be useful).

4. If you are called to interview, whether you would require any special facilities at the interview (please provide as much information as possible, and we will do our best to accommodate your request).

Equal Opportunities Policy

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In the recruitment, selection, training, appraisal, development and promotion of staff, the only consideration must be that the individual meets, or is likely to meet the requirements of the post. The requirements being met, no job applicant or employee will be discriminated against on the basis of their gender, race, colour, ethnic origin, nationality (within current legislation), disability, sexual marital status, caring or parental responsibilities, age, or beliefs on matters such as religion and politics.

The full policy statement can be found at: http://www.ucl.ac.uk/hr/docs/equal_opportunity.php

Unfortunately we cannot write to applicants who are not shortlisted. Consequently, if you have not heard from ICH within four weeks of the closing date, please assume that you have not been shortlisted. We hope that this does not discourage you from making further applications in the future.

Where to send the application

Applications should be sent to:

Mrs Katie WhiteHuman Resources OfficeInstitute of Child Health30 Guilford StreetLondonWC1N 1EH

We can be contacted by email at k.white@ich.ucl.ac.uk or by telephoning 020 7905 2741

Closing date for applications: 12th November 2008

We particularly welcome female applicants and those from an ethnic minority, as they are under-represented within UCL at these levels. This is in line with section 48 of the Sex Discrimination Act and section 38 of the Race Relations Act.

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