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The Mini-Gastric Bypass:The Mini-Gastric Bypass:vs.vs.
Roux-en-Y BypassRoux-en-Y Bypass
Dr K S KularKular Medical Education & Research Society ,
Kular Group of Institutes ,[email protected]
www.kularhospital.com
RNY is the MOST Dangerous Form of Bariatric Surgery
By Every measure, in Every study RNY
Highest Death Rate, Highest Leak Rate, Highest Early Complications,
Highest Major Complication Rate, Highest Rate Bowel Obstruction
Highest Bleeding Rate, Highest Re-operation Rate Highest PE Rate....
RNY is Without Question, the most dangerous form of Bariatric Surgery; References >100 Studies
Mini-Gastric Bypass
Very Safe/Very Good Results Gastric + Bypass (Restrictive + Malabsorptive)Minimal Weight Regain Minimal GERDVery High Patient SatisfactionVery easy to Revise
What is the BEST Source Medical Truth:Randomized Controlled Prospective Trials!
The Randomized Controlled Trial, Considered
The ''Gold Standard'' For Source of Medical Truth
What is the TRUTH About RNY Gastric Bypass
Recent Controlled Prospective Trials of RNY
At some of the best hospitals in the world
Controlled Prospective Randomized RNY Trial ! JAMA 2013
Some of the Best Hospitals in the WorldControlled Prospective Randomized Trial in Relatively
Healthy Pts12 months ONLY 44% Diabetics normal HgbA1c levels37% serious complications 3.3% Leaks!!! 1 patient suffered
Sepsis, anoxic brain injury and amputation!
Basics of MGB
Both Restrictive + Major Fat Malabsorption
Technically Straight forward
Low Risk (Complications/Leak)
Very Low Risk of SBO (0-0.3%)
Very High Weight Loss; Rare Regain
Bile Reflux rare and easily Rx (Experience with >12,000 MGB)
Fear of Gastric Cancer unfounded (a Hot Dog is more dangerous risk of Gastric Cancer)
MGB Very Effective & Very Safe
MGB SeriesRutledge U.S.A. 6,000 + (16 yr + FU)Cady France 2000 +Peraglie U.S.A. 2000 +Carbajo Spain 2000 +Noun Lebanon 1000Lee Taiwan 1000 + (RCT, 10 yr+ FU)Kular India 1000+Garcia-Caballero Spain 1000 +Musella et al. Italy 1000Others (i.e. Chevallier Paris 700,
Tacchino Rome 500, etc.)
MGB One of the Most Effective & Safest
MGB SeriesFindings in all series are the same:1. Short operation, low risk of short and long term
complications2. Excellent short and long term weight loss
75-100% EWL, (Better than BPD)3. Revisable and Reversible4. Minimal Risk of Bile Reflux in Knowledgeable Hands
One Thousand Consecutive Mini-gastric Bypass: Short- And Long-term Outcome
1,000 patients who underwent MGB from November 2005 to January 2011
Operative time and length of stay for primary vs. revisional MGB were
89 ± 12.8 min vs. 144 ± 15 min (p < 0.01) and
1.85 ± 0.8 day vs. 2.35 ± 1.89 day (p < 0.01)
Short-term complications 2.7%
Obes Surg. 2012 May;22(5):697-703. One thousand consecutive mini-gastric bypass: short- and long-term outcome. Noun et al, Department of Digestive Surgery, Hôtel-Dieu de France Hospital and University Saint Joseph Medical School, Bd Alfred Naccache, Achrafieh, BP 166830 Beirut, Lebanon. [email protected]
One Thousand Consecutive Mini-gastric Bypass: Short- And Long-term Outcome
Five (0.5%) patients presented with leak.
Four (0.4%) patients, all revisions with severe bile reflux Rx by stapled latero-lateral jejunojejunostomy (Braun).
Excessive weight loss occurred in four patients easily revised.
Percent excess weight loss (EWL) of 72.5% occurred at 18 months.Obes Surg. 2012 May;22(5):697-703. One thousand consecutive mini-gastric bypass: short- and long-term outcome.
Noun et al, Department of Digestive Surgery, Hôtel-Dieu de France Hospital and University Saint Joseph Medical School, Bd Alfred Naccache, Achrafieh, BP 166830 Beirut, Lebanon. [email protected]
One Thousand Consecutive Mini-gastric Bypass: Short- And Long-term Outcome
The 50% EWL was achieved for 95% of patients at 18 months and for 89.8% at 60 months.
MGB is an effective, relatively low-risk, and low-failure bariatric procedure.
In addition, it can be easily revised, converted, or reversed.
Obes Surg. 2012 May;22(5):697-703. One thousand consecutive mini-gastric bypass: short- and long-term outcome. Noun et al, Department of Digestive Surgery, Hôtel-Dieu de France Hospital and University Saint Joseph Medical School, Bd Alfred Naccache, Achrafieh, BP 166830 Beirut, Lebanon. [email protected]
Controlled Prospective Randomized Trial Lee WJ, Yu P-J, Wang W, Chen TC, Wei PL, Huang MT. Laparoscopic Roux-en-Y versus Mini-Gastric Bypass for the
treatment of Morbid Obesity. Ann Surg 2005 ; 242 : 20-28
RYG Bypass Mini Bypass
Op time (mns) 205 148Early complications 20.1% 7.5%Late complications 7.5% 7.5 %
EWL at one year 58.7% 64.9% EWL at two years 60% 64.4%
Randomized Controlled Prospective TrialsMGB MUCH Superior to RNY Rx Diabetes
MGB vs RNY Rx Diabetes, Two Controlled Prospective Randomized Trials
Ikramuddin S, et al. Roux-en-Y gastric bypass vs intensive medical management for the control of type 2 diabetes, hypertension, and hyperlipidemia: the Diabetes Surgery Study randomized clinical trial. JAMA. 2013 Jun
Lee WJ, et al. Gastric bypass vs sleeve gastrectomy for type 2 diabetes mellitus: a randomized controlled trial. Arch Surg. 2011 Feb
Resolution of Diabetes at 12 months
Sleeve 47%
RNY 44%
MGB 93%
WHY MGB?
Why Consider the MGB?With the Band/Sleeve/RNY available
Why even consider the Mini-Gastric Bypass?
Is Bariatric Surgery Worth It?
Comment on “Impact of Bariatric Surgery on Health Care Costs of Obese Persons”
Edward H. Livingston, MD
JAMA Surg. 2013;148(6):561
Why Consider MGB?Long Term Failure of Band / RNY
6 yr study 29,820 BCBS plan members.
"Laparoscopic RNY and Lap Band both Fail to reduce overall health care costs in the long term."
Impact of Bariatric Surgery on Health Care Costs of Obese Persons, A 6-Year Follow-up of Surgical and Comparison Cohorts Using Health Plan Data Jonathan P. Weiner, et al. JAMA Surg. 2013;148(6)
Long-term follow-up from the Swedish Obese Subjects study reported in JAMA showed that although fewer medications were used by bariatric patients compared with controls, the bariatric patients used substantially more hospital resources.
A formal cost-effectiveness study using very high-quality data from the US Department of Veterans Affairs did not show a cost benefit for Roux-en-Y gastric bypass.
Band/RNY Failure to Demonstrate benefit
Analysis of BlueCross Blue Shield patients for 6 years failed to demonstrate a benefit for Band or RNY
Coupled with findings that bariatric surgery confers little to no long-term survival benefit,4 these observations show that
bariatric surgery does not provide an overall societal benefit.
xxx
Band & RNY fail to reduce healthcare costsHealthcare Costs of RNY and Band
RNYBand
Why Consider MGB?
Why Consider Mini-Gastric Bypass?
Best Rx for Diabetes5 Objectives
1. Consider Band/Sleeve/RNY/MGB2. Best Rx DM Requires
Gastric Procedure + Duodenal Bypass3. Eliminates Band/Sleeve; Choice RNY vs MGB4. RNY Most Technically Difficult Dangerous &
Deadly form of Bariatric Surgery5. Data MGB One of the Most Effective & Safest
Rx for DM
Objective 1:Consider Band/Sleeve/RNY/MGB
Objective 2: Best Treatment of Diabetes Includes
Both a Gastric Procedure + Duodenal Bypass
Data from General Surgery, Bariatric Reports, Animal Studies
Objective 2: Animal Models Confirm
Duodenal Bypass Improves Effectiveness
“This study shows that bypassing Duodenum Improves T2D, independently of food intake, body weight, malabsorption, or
nutrient delivery”
The Mechanism of Diabetes Control After Gastrointestinal Bypass Surgery Reveals a Role of the Proximal Small Intestine in the Pathophysiology of Type 2 Diabetes. Rubino,); Marescaux, Jacques MD, FRCS Annals of Surgery; 244 (5): 741-749, November 2006
Objective 2: Billroth I vs Billroth IIGastrectomy vs Gastrectomy + Bypass
Primary Gastric Procedure (PGP)
Vs
Combined Gastric + Bypass (CGB)
Which Leads to Greater Weight Loss?
Which Leads to Greater Resolution of Diabetes?
General Surgery Answer:
Bariatric Surgeons Should Not Forget Their General Surgery Training
GS for Gastric Disease (Ca/Ulcer)
Gastrectomy ALONE 50%
Gastrectomy + Duodenal Bypass 75%
Rx T2D MUST Include Duodenal Bypass for BEST short and long term Efficacy
G.O. Less Effective G+D G.O.=Gastric Only vs G+D=Gastric + Duodenal
Outcome after gastrectomy in gastric cancer patients with type 2 diabetes
• 403 gastric cancer patients with T2DM• BMI % Reduction• Duodenal Bypass:• BI: No Bypass 7.6%• BII: Bypass 11.4%• ** 50% Improvement **
• Jong Won Kim, etal, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 135-720, South Korea, World J Gastroenterol. 2012 January 7; 18(1): 49–54.
Objective 2: General Surgery"Effect of Gastrectomy For
Stomach Cancer on Type 2 Diabetes Mellitus"
Kang KC, Shin SH, Lee YJ, Heo YS. J Korean Surg Soc. 2012 Jun;82(6):347-55.
Department of Surgery, Inha University Hospital, Inha University School of Medicine, Incheon, Korea.
Objective 2: Gastrectomy for stomach cancer on type 2 diabetes (Kang)
75 GCa Pts, 35 month FUBI vs BII Rx DMGastrectomy ALONE (i.e. Sleeve)
0% Resolved, 45% improvedGastrectomy + BII (i.e. MGB)
22% Resolved, 85% Improved
Objective 2: General SurgeryJ Gastrointest Surg. 2012 Jan;16(1):45-51
Gastrointestinal metabolic surgery for the treatment of diabetic patients: a multi-
institutional international study.
Lee WJ, Hur KY, Lakadawala M, Kasama K, Wong SK, Lee YC.
Gastrointestinal metabolic surgery for the treatment of diabetic patients (Lakadawala)
200 patients, Gastric Bypass vs Sleeve gastrectomy Remission of T2DM “Gastric Bypass pts (Gastric + Bypass)
lost more weight & higher diabetes remission Sleeve pts“Bypass pts mix of MGB/RNY
(per Dr. Lee)
Objective 2: MGB vs Sleeve
Mini-Gastric bypass vs Sleeve Gastrectomy
for type 2 diabetes mellitus: a Randomized Controlled TrialRandomized Controlled Trial
Lee WJ, Chong K, Ser KH, Lee YC, Chen SC, Chen JC, Tsai MH, Chuang
LM. Arch Surg. 2011 Feb
Objective 2: Lee MGB vs SleeveRandomized Controlled Trial
Randomized controlled trial
60 moderately obese patients (body mass index >25 and <35)
Outcome was remission of T2DM (fasting glucose <126 mg/dL and HbA(1c) <6.5% without glycemic therapy)
All completed the 12-month follow-up
Lee MGB vs SleeveRandomized Controlled Trial
Remission of Diabetes
** 93% ** Mini-gastric bypass
** 47% ** Sleeve gastrectomy
(P = .02)
Lee MGB vs SleeveRandomized Controlled Trial
Mini-gastric bypass
lost more weight,
achieved a lower waist circumference, and
Lower glucose, HbA(1c), and
blood lipid levels than
the sleeve gastrectomy group
Effectiveness of Bariatric ProceduresGastric + Duodenal BypassOutperforms Gastric Alone
G.O. Band PoorG.O. Sleeve Med HighG+D RNY HighG+D MGB High - HighestConclusions
Band & Sleeve Less Effective than RNY & MGB
Objective 3: Best Rx DM Gastric Procedure + Duodenal Bypass
This Excludes Band/Sleeve
Need for Gastric Procedure +Bypass
Eliminates Band/Sleeve;
Leaves Choice RNY vs MGB
Objective 4: RNY is the most
Technically Difficult, Dangerous & Deadly
form of Bariatric Surgery
>100 RefsOne Recent Example
RNY is the MOST Dangerous Form of Bariatric Surgery
By Every measure, in Every study RNY Highest Death Rate, Highest Leak Rate Highest Early Complications Highest Major Complication RateHighest Bleeding Rate, Highest Re-operation RateHighest PE Rate....RNY is the most dangerous form of Bariatric SurgeryReferences 25-100 Studies
RNY: Long learning curve of 500 cases
RNY technically challenging 2,281 cases 1999 - 2011
Complications Stabilized after *500* cases Mortality rate .43%,
main causes of death PE & Leaks (.14% each)Op time & Complications significantly reduced after a
long learning curve of 500 cases Surg Obes Relat Dis. 2013 Feb 11. Overcoming the learning curve of laparoscopic Roux-en-Y gastric bypass: A 12-year experience.
El-Kadre L, Tinoco AC, Tinoco RC, Aguiar L, Santos T. Department of Surgery, São José do Avaí Hospital, Itaperuna, Rio de Janeiro, Brazil.
Lap RNY Gastric Bypass
Med Coll Va. Postoperative Complications L-RNY
Leak 4.5%SBO 2%PE 1%Death 0.7%
Ann Surg. 2004 May; 239(5): 698–703. Multivariate Analysis of Risk Factors for Death Following Gastric Bypass for Treatment of Morbid Obesity, Adolfo Z. Fernandez, Jr, MD et al.
RNY Bypass Surgery for Diabetes With Nonmorbid Obesity? Maybe Jun 04, 2013
Controlled Prospective Rndomized 12-months, 49% RNY pts vs 19% lifestyle pts met primary end points
BUT37% serious complications in the RNY group 2 most serious complications were anastomotic leak 3.3%!!, 1 patient suffered anoxic brain injury. Patients who underwent surgery were also more likely to have
nonserious adverse events such as nutritional deficiencies.
JAMA. 2013 Jun 5;309(21):Roux-en-Y gastric bypass vs intensive medical management for the control of type 2 diabetes, hypertension, and hyperlipidemia: the Diabetes Surgery Study randomized clinical trial. Ikramuddin S, Department of Surgery, School of Public Health, University of Minnesota, Minneapolis, MN 55455, USA. [email protected]
RNY Bypass Surgery for Diabetes Controlled Prospective Randomized Trial
Normal HgbA1C level range from 4.5 to 6
Only 44% RNY pts HgbA1c < 6 (Cure)BUT
37% serious complications in the RNY group
3.3% anastomotic leaks
1 patient suffered anoxic brain injury.
JAMA. 2013 Jun 5;309(21):Roux-en-Y gastric bypass vs intensive medical management for the control of type 2 diabetes, hypertension, and hyperlipidemia: the Diabetes Surgery Study randomized clinical trial. Ikramuddin S, Department of Surgery, School of Public Health, University of Minnesota, Minneapolis, MN 55455, USA. [email protected]
1 yr RNY Did NotReachNormalHgbA1c
JAMA. 2013 Jun 5;309(21):Roux-en-Y gastric bypass vs intensive medical management for the control of type 2 diabetes, hypertension, and hyperlipidemia: the Diabetes Surgery Study randomized clinical trial. Ikramuddin S, Department of Surgery, School of Public Health, University of Minnesota, Minneapolis, MN 55455, USA. [email protected]
First report from the American College of Surgeons
Bariatric Surgery Center Network28,000 Patients
Ann Surg. 2011 Sep;254(3):410-20
Hutter MM, Schirmer BD, Jones DB, Ko CY, Cohen ME, Merkow RP, Nguyen NT.
Department of Surgery, Massachusetts General Hospital, Boston, MA 02114, USA.
American College of Surgeons Bariatric Surgery Center Network
Outcome SG N (%)RNY N (%)
Conv to Open 9 (0.10) 207 (1.43)
30-day Mortality 1 (0.11) 21 (0.14)
1-Year Mortality 2 (0.21) 49 (0.34)
Readmission 51 (5.4) 937 (6.47)
Reoperation28 (2.97) 728 (5.02)First report from the American College of Surgeons Bariatric Surgery Center Network28,000 Patients
American College of Surgeons Bariatric Surgery Center Network
Outcome LSG N (%) RNY N (%)Coma 0 2 (0.01)Stroke 0 5 (0.03)Cardiac Arrest0 13 (0.09)Myocard Infarct 0 9 (0.06)DVT 1 (0.11) 21 (0.14)Pneumonia3 (0.32) 58 (0.40)
American College of Surgeons Bariatric Surgery Center Network
Outcome SG N (%) RNY N (%)Intubation 3 (0.3) 59 (0.41)Ventilator (> 48 hrs) 0 55 (0.38)Acute Renal Failure 0 22 (0.15)UTI 5 (0.5) 104 (0.7)Wound Dehiscence 0 27 (0.19)Septic Shock 0 21 (0.14)
Controlled Prospective Randomized Trial Lee WJ, Yu P-J, Wang W, Chen TC, Wei PL, Huang MT. Laparoscopic Roux-en-Y versus Mini-Gastric Bypass
for the treatment of Morbid Obesity. Ann Surg 2005 ; 242 : 20-28
RYG Bypass Mini Bypass
Op time (mns) 205 148Early complications 20% 7.5%Late complications 7.5% 7.5 %
EWL at one year 58.7% 64.9% EWL at two years 60% 64.4%
Objective 5: MGB One of the Most Effective & Safest
Best Rx for DM
Objective 5:MGB One of the Most Effective & Safest
MGB SeriesRutledge U.S.A. 6,000 + (16 yr + FU)Lee Taiwan 1000 + (RCT, 10 yr+ FU)Noun Lebanon 1000Kular India 1000+Cady France 2000 +Peraglie U.S.A. 2000 +Carbajo Spain 2000 +Garcia-Caballero Spain 1000 +Musella et al. Italy 1000Otheres (i.e. Chevallier Paris , Tacchino Rome etc.)
MGB One of the Most Effective & Safest
MGB SeriesFindings in all series are the same:Short operation, low risk of short and long term
complicationsExcellent short and long term weight loss 75-100% EWL,
Better than BPD)Revisable and ReversibleMinimal Risk of Bile Reflux in Knowledgeable Hands
One Thousand Consecutive Mini-gastric Bypass: Short- And Long-term Outcome
1,000 patients who underwent MGB from November 2005 to January 2011
Operative time and length of stay for primary vs. revisional MGB were
89 ± 12.8 min vs. 144 ± 15 min (p < 0.01) and
l.85 ± 0.8 day vs. 2.35 ± 1.89 day (p < 0.01)
Short-term complications 2.7% for primary vs. 11.6% for revisionnal MGB (p < 0.01)
Obes Surg. 2012 May;22(5):697-703. One thousand consecutive mini-gastric bypass: short- and long-term outcome. Noun et al, Department of Digestive Surgery, Hôtel-Dieu de France Hospital and University Saint Joseph Medical School, Bd Alfred Naccache, Achrafieh, BP 166830 Beirut, Lebanon. [email protected]
One Thousand Consecutive Mini-gastric Bypass: Short- And Long-term Outcome
Five (0.5%) patients presented with leakage from the gastic tube but none had anastomotic leakage.
Four (0.4%) patients, all revisions with severe bile reflux Rx by stapled latero-lateral jejunojejunostomy (Braun).
Excessive weight loss occurred in four patientseasily revised.
Percent excess weight loss (EWL) of 72.5% occurred at 18 months.Obes Surg. 2012 May;22(5):697-703. One thousand consecutive mini-gastric bypass: short- and long-term outcome.
Noun et al, Department of Digestive Surgery, Hôtel-Dieu de France Hospital and University Saint Joseph Medical School, Bd Alfred Naccache, Achrafieh, BP 166830 Beirut, Lebanon. [email protected]
One Thousand Consecutive Mini-gastric Bypass: Short- And Long-term Outcome
The 50% EWL was achieved for 95% of patients at 18 months and for 89.8% at 60 months.
MGB is an effective, relatively low-risk, and low-failure bariatric procedure.
In addition, it can be easily revised, converted, or reversed.Obes Surg. 2012 May;22(5):697-703. One thousand consecutive mini-gastric bypass: short-
and long-term outcome. Noun et al, Department of Digestive Surgery, Hôtel-Dieu de France Hospital and University Saint Joseph Medical School, Bd Alfred Naccache, Achrafieh, BP 166830 Beirut, Lebanon. [email protected]
Laparoscopic Roux-en-y Vs. Mini-gastric Bypass For The Treatment Of Morbid Obesity: A 10-year Experience.
Obes Surg. 2012 Dec;22(12):1827-34. Laparoscopic Roux-en-Y Vs. mini-gastric bypass for the treatment of morbid obesity: a 10-year experience.
Lee WJ, Ser KH, Lee YC, Tsou JJ, Chen SC, Chen JC.
Department of Surgery, Min-Sheng General Hospital, National Taiwan University, No. 168, Chin Kuo Road, Tauoyan, Taiwan, Republic of China. [email protected]
Laparoscopic Roux-en-y Vs. Mini-gastric Bypass For The Treatment Of Morbid Obesity: A 10-year Experience.
October 2001 and September 2010, 1,657 patients who received gastric bypass surgery (1,163 for LMGB and 494 for LRYGB)
Surgical time was significantly longer for LRYGB (159.2 vs. 115.3 min for LMGB, p < 0.001).
The major complication rate was higher for LRYGB (3.2 vs. 1.8%, p = 0.07).
5 years after surgery, the mean BMI was lower in LMGB than LRYGB (27.7 vs. 29.2, p < 0.05) and
LMGB also had a higher excess weight loss than LRYGB (72.9 vs. 60.1%, p < 0.05).
Late revision rate was LRYGB 3.6% and MGB 2.8%
Laparoscopic Roux-en-y Vs. Mini-gastric Bypass For The Treatment Of Morbid Obesity: A 10-year Experience.
CONCLUSIONS:This study demonstrates that MGB
can be regarded as a SIMPLER and SAFER alternative to RNY with similar or BETTER efficacy at a 10-year experience.
Surgery Can Successfully Treat Obesity and Diabetes in Both Thin and Obese Diabetic Patients
• 2013: Kular Hospital• 6 year study T2DM
patients • Results:• Type 2 Diabetes
resolved • 98% of MGB
MGB More Effective than BPDDr Tacchino MGB vs BPD
Weight Loss and Diabetes Resolution Following Mini-Gastric Bypass and Bilio-Pancreatic Diversion. Tacchino R.,
Rutledge R., Università Cattolica del Sacro Cuore, Rome, Italy 408 pts Jan 2007 to Dec 2009 36 months follow-up Mini-Gastric Bypass (n = 164) initial BMI 46.4±9.6 or Bilio-Pancreatic Diversion (n = 244) initial BMI 46.9±7
(Tacchino’s perferred Operation)
MGB More Effective than BPDDr Tacchino MGB vs BPD
RESULTS:
Mean BMI at two years was 28.5±3.9 kg/m2 and at three years 27.4±4.5 kg/m2 after MGB
BMI at two years 32.7± 6.04 kg/ m2 and at three years 33.6±5.1 kg/m2 after BPD
One year resolution of diabetes was accomplished in:
100% in MGB group
95% in BPD group.
MGB More Effective than BPDDr Tacchino MGB vs BPD
Tacchino’s conclusions:
“Both MGB and BPD resluted in excellent weight loss, excellent resolution of co-morbities with low risk of long term complications.
The MGB was associated with greater weight loss than BPD.
Improvements in other cardiovascular risk factors and quality of life were similar after both procedures.”
Randomized Controlled Prospective TrialsMGB MUCH Superior to RNY Rx Diabetes
MGB vs RNY Rx Diabetes, Two Controlled Prospective Randomized Trials
Ikramuddin S, et al. Roux-en-Y gastric bypass vs intensive medical management for the control of type 2 diabetes, hypertension, and hyperlipidemia: the Diabetes Surgery Study randomized clinical trial. JAMA. 2013 Jun
Lee WJ, et al. Gastric bypass vs sleeve gastrectomy for type 2 diabetes mellitus: a randomized controlled trial. Arch Surg. 2011 Feb
Resolution of Diabetes at 12 monthsSleeve 47%
RNY 44%MGB 93%
Conclusions: MGB Best Rx for DM
1. Band/Sleeve/RNY/MGB2. Animal, Gen Surg and Bariatric Data:
Best Rx = Gastric + Duodenal Bypass3. Excludes Band/Sleeve4. RNY Unquestionably the Most Dangerous form of
Bariatric Surgery5. Numerous studies show MGB short safe and highly
effective; Best Choice
Which Is More Deadly Which Is More Deadly A Hot Dog Or A Billroth II?A Hot Dog Or A Billroth II?
Which Is More Deadly A Hot Dog Or A Billroth II?
Processed meats (Bacon, sausage, hot dogs, sandwich meat, packaged ham, pepperoni, salami, etc.)
Shown to be associated with gastric cancer. An increase intake of 100 g of processed meat per day Increases the risk of Gastric Cancer by 3.5 times= Natl Cancer Inst. 2006 Mar 1;98(5):345-54. Meat intake and risk of stomach and esophageal adenocarcinoma within
the European Prospective Investigation Into Cancer and Nutrition (EPIC).
= J Natl Cancer Inst. 2006 2;98(15):1078 "Processed meat consumption and stomach cancer risk: a meta-analysis" The Karolinska Institutet
(Hint: A Hot Dog weight 3.7 oz = 100 g = INCREASED RISK 3.5!)
Which is more deadly a Hot Dog or a Billroth II?
AA BBhttps://www.surveymonkey.com/s/IFSO-MGB-ConsensusConference
Or Email [email protected]
Which is more deadly a Hot Dog or a Billroth II?
0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
100%
A daily serving of processed meat Billroth II
88%
13%
Which Do Bariatric Surgeons Fear More? A Hot Dog or a Billroth II?
AA BBhttps://www.surveymonkey.com/s/IFSO-MGB-ConsensusConference
Or Email [email protected]
UNINFORMED FEAR BILLROTH IIEDUCATED USE BILLROTH II• 1. Gastric Cancer Declining Rapidly, > 50%
• 2. Gastric Cancer Cause: Environmental Factors / Easily Prevented
Diet, Lifestyle changes and Rx of H. Pylori
(Avoid Etoh, smoking, processed & salted meats and foods, seek high intake of fruits and vegetables)
UNINFORMED FEAR BILLROTH IIEDUCATED USE BILLROTH II
• 3. Some studies Slight Increased Risk of gastric cancer after 20 – 30 years (RR 1.5):But: BII was performed to Rx Ulcer => Ulcer => Increased Risk
• (Worried? Rx H Pylori, Eat healthy etc.)
• 4. Many Large Studies: No Increased RiskThousands of patients followed for Decades
UNINFORMED FEAR BILLROTH IIEDUCATED USE BILLROTH II
• 5. Endoscopic screening of Billroth II patients is Not Recommended. Why? Low Risk!
• 6. General, Trauma and Oncologic surgeons routinely use the Billroth II (Thousands of publications)
• 7. 2007 ~16,000 BII procedures were performed in the USA
UNINFORMED FEAR BILLROTH IIEDUCATED USE BILLROTH II
• 8. Billroth II and the Mini-Gastric BypassExcellent, Safe and Effective
• 9. FEAR Gastric Cancer? Avoid ETOH, Tobacco, Processed & Preserved Meats, Rx H. Pylori, Eat Fruits and Veggies, Yogurt and Drink Green Tea
• A Billroth II probably makes NO difference
T: TRADEOFFS• Rational Review of the Data vs.
Fear Gastric Cancer / Bile Reflux• Rational Thinking vs. Reptilian Brain
T: TRADEOFFS: Rational Data Analysis vs. Irrational FEAR Gastric Cancer
• 1. Gastric Cancer Declining Rapidly• 2. GC Environmental Causes; Easily Prevented• 3. Some studies show Small Increased Risk
Probably from Ulcers / H. Pylori
• 4. Many large studies: NO increased risk
• 5. Endoscopic Screening: Not Recommended • 6. General, Trauma & Oncologic Surgeons Use Billroth II
T: TRADEOFFS FEAR OF GASTRIC CANCER
• FEAR gastric cancer?
• Avoid: Alcohol, Tobacco, Processed & Preserved MeatsRx: H. Pylori, Eat Fruits & Veggies, Yogurt and Drink Green Tea
• Billroth II Probably Makes NO DifferenceBillroth II Probably Makes NO Difference
Bariatric Surgery Rx Type 2 Diabetes
Bariatric Surgery Has Been shown to Successfully Treat Type 2 Diabetes Mellitus
Unfortunately Failure of Bariatric Procedures Rx of T2D is reported
Operations to be considered: Band/Sleeve/RNY vs MGB
Bariatric Surgeons Should Not Forget Their General Surgery Training
• Bariatric Surgeons should Learn from General Surgery • General Surgery and T2D• Results of General Surgery for Gastric
Disease • Cancer / Ulcer
Laparoscopic Mini Gastric BypassCesare Peraglie MD FACS FASCRS
CLOS-Florida: Heart of Florida Regional Medical Center.Davenport, Florida
SECO 2012BARCELONA SPAIN
Laparoscopic-Mini Gastric Bypass: HOFRMC
•Over 1000 Laparoscopic MGB’s have been performed at HOFRMC since 2005.
•TYPICAL DEMOGRAPHICS: AGE: 45 (14-72), BMI: 45 (30-75), ~27% DIABETIC, ~50% HTN, ~31% PREVIOUS ABDOMINAL SURGERY
•OUTCOMESOP-TIME: 62Min. (37-186), Conversion to open: 0LOS: 1 DAY or less (88%), 2 DAY (10%), 3 DAY (~2%), 4+ DAY
(<1%)Re-admission: 5% (23 hour obs. PONV in all but one) / 0.8%
90 dayLeak: 0.3%MORTALITY: 0 (HOSPITAL), 0 (PERI-OP:90D)
RNY & Small Bowel Obstruction
Every Testbook in General Surgery Warns of SBO after RNY
RNY Causes Bowel Obstruction and Death
• My family member had RNY=>SBO=>Death
• RNY SBO 2-16%
• NO Other Bariatric Surgery Has Such High Rate of Bowel Obstruction
Some RNY Surgeons Never See Bowel Obstruction after RNY
How Can this Be?
Poor Follow UpMakes Good Results
RNY SBO 2-16%
RNY Surgeons Leave SBO to be Cleaned Up by General Surgeons
Every General Surgeon
is Now TaughtTo Look For,
Be Vigilant and Fear
Bowel ObstructionAfter RNY
Gastric Bypass
Poor Follow UpMakes Good Results
My Family Member
Who DIED
From Small Bowel Obstruction After RNY
Was Operated Upon by a
GENERAL Surgeon not a Bariatric Surgeon!
Her RNY Surgeon Does Not Know of her Death or her Bowel Obstruction
Mini-Gastric BypassBy Every Important Measure the Best Choice for Rx Type 2 DM
Compared to RNY: Efficacy/Safety
One of the Highest Efficacy of Rx T2D
Highest Safety
Lowest Death Rate
Lowest Leak Rate
Lowest Early Complication Rate
Lowest Major Complication Rate
Lowest Bleeding Rate
Lowest Re-operation Rate
Lowest PE Rate
By Every Measure and in Every Study
Lap RNY Gastric Bypass
Med Coll Va. Postoperative Complications L-RNY
Leak 4.5%SBO 2%PE 1%Death 0.7%
Ann Surg. 2004 May; 239(5): 698–703. Multivariate Analysis of Risk Factors for Death Following Gastric Bypass for Treatment of Morbid Obesity, Adolfo Z. Fernandez, Jr, MD et al.
Lap RNY Gastric Bypass
Med Coll Va. Postoperative Complications L-RNY
Leak 4.5%SBO 2%PE 1%Death 0.7%
Ann Surg. 2004 May; 239(5): 698–703. Multivariate Analysis of Risk Factors for Death Following Gastric Bypass for Treatment of Morbid Obesity, Adolfo Z. Fernandez, Jr, MD et al.
Patient Satisfaction
Kular Hospital Community Hospital No Advertisement: Offer Sleeve, RNY or MGB
Patients are followed
Sleeve pts frequently complain of N/V and referr fewer pats for operation
RNY Less satisfaction poor referral discouraged
MGB high satisfied and refer many patients
NOW 90% of cases are MGB
India Turns to the Sleeve
Band has come and gone
Many RNY programs
Centers across India turning to sleeve for the same reasond
Selecting an Operative ProcedureSafety and Effectiveness
Personal Experience, Animal Models, Expert Judgment, Published Data and Controlled Prospective Randomized
Trials all show:
MGB is More Effective than Sleeve \RNYMGB is Safer than Sleeve\RNY
Mini-Gastric Bypass: Excellent Results from Multiple
Surgeons
6,385 Consecutive Mini-Gastric Bypasses: 16 Years Later (Rutledge)
6,385 patients who underwent MGB from September 1997 to June 2011
Mean operative time 41 minutes and median length of stay 1 day
Early complications occurred in 4.9%.
44 (0.7%) patients had anastomotic leaks.
Three (0.05%) patients presented with dypepsia/bile reflux not responsive to medical therapy and were successfully treated by Braun side-to-side jejuno-jejunostomy.
6,385 Consecutive Mini-Gastric Bypasses: 16 Years Later (Rutledge)
Gastritis/dyspepsia/marginal ulcer was the most serious long term complication; routinely treated medically.
Excessive weight loss occurred in 1% of patients; treated by take down of the bypass.
Mean % excess weight loss (EWL) of 78%.
10 year weight regain was mean 4.9%. >50% EWL was achieved for 95% of patients at 18 months and for 92% at 60 months.
6% of patient had inadequate weight loss or significant weight regain were treated by revision, (addition of ~2 meters to the bypass).
Remember!All Medical and Surgery Can Fail!
Bariatric Surgery Procedures are Known to FailTherefore
ALWAYS CHOOSEOperation that Can Be Revised Safely!!
NEVER CHOOSE Operation Revision is Dangerous!
Revision of MGB: Easily Done Rarely Needed
Revisional Surgery For Laparoscopic Mini-Gastric Bypass
Wei-Jei Lee, M.D., Ph.D. , Yi-Chih Lee, Ph.D., Kong-Han Ser, M.D., Shu-Chun Chen, R.N.,
Jung-Chien Chen, M.D., Yen-How Su, M.D.
Surgery for Obesity and Related DiseasesVolume 7, Issue 4 , Pages 486-491, July 2011
Revision of MGB: Easily Done Rarely Needed
January 2001 to December 2009, 1322 patients excess weight loss and mean body mass index at 5 years after
LMGB was 72.1% and 27.1 ± 4.6 kg/m2. Of the 1322 patients, 23 (1.7%) had undergone revision surgery
during a follow-up of 9 years.The causes of revision Malnutrition (Excess Weight Loss) in 9 casesInadequate weight loss in 8 Intractable bile reflux 3 out of 1,322 cases, No patients had surgery for Internal hernia
FIRST International Consensus Conference on Mini-Gastric Bypass
Paris in October 2012.
The IFSO-EC Mini-Gastric BypassPostgraduate Course in Barcelona in April 2012 was a notable success
• As you may know we had a great slate of presenters included such experts and leaders included
• Prof Jean-Marc Chevallier, France, Prof Roberto Tacchino,Italy, Prof. Dr. Manuel Garcia-Caballero, Spain, Dr. Jean Mouiel,France, Dr. Rui Ribeiro, Dr. Cesare Peraglie, M.D., F.A.C.S., USA, Dr. Mario Musella and Dr. K S Kular M.S. from India; and others.
https://www.surveymonkey.com/s/CCVote Or Email [email protected]
Society of Mini-Gastric Bypass SurgeonsIssues (To Do) List
00. ISSUES
01. FIRST PRINCIPLES
02. NAMING/RENAMING THE MINI-GASTRIC BYPASS
04. THE PRESENT SATE OF THE MGB
05. NATIONAL AND INTERNATIONAL RECOGNITION OF THE MGB
06. INTERNATIONAL MGB REGISTRY
07. MENTORING PROGRAMS FOR NEW MGB/OL SURGEONS
08. SHARING INFORMATION
09. MGB RESEARCH PLANS
10. STANDARD PRE-OP EVALUATION PROCESS
11. STANDARD PRE-OPERATIVE PERMIT
12. PREOP MANAGEMENT OF MINI-GASTRIC BYPASS
13. ANESTHESIA MANAGEMENT OF MINI-GASTRIC BYPASS
14. STANDARDIZED MGB OPERATIVE PROCEDURE
15. POST OPERATIVE MGB MANAGEMENT
16. MANAGEMENT OF MGB COMPLICATIONS
17. OTHER TOPICS (COMMITTEE’S SUGGESTIONS)
IFSO – EC Mini-Gastric Bypass Post Grad Course, April Barcelona
The countries represented included France, Italy, Germany, Spain, the United Kingdom, the Czech Republic, Portugal, Egypt, United Arab Emirates, the Netherlands and India.
We were pleased that the room was near full, enthusiastic and educational.
As a follow up, the Society of MGB Surgeons is seeking to survey the present opinions of surgeons about the MGB and the other bariatric procedures.
https://www.surveymonkey.com/s/CCVote
Society of MGB SurgeonsMGB / OAGB Survey Respondents
https://www.surveymonkey.com/s/IFSO-MGB-ConsensusConference Or Email [email protected]
Society of MGB Surgeons: Rename the Mini-Gastric Bypass?
Dr. Rutledge & Experts Around the World:We Want to Help You!
USA 001-702-714-0011 [email protected]
CONSIDERING THE MGB?MGB IS A SUPERB SURGERY BUT…
WARNING: “THERE ARE “TRICKS AND TRAPS”“THERE ARE “TRICKS AND TRAPS”
https://www.surveymonkey.com/s/CCVote Or Email [email protected]
MGB Survey Findings
• Low VolumeLow Volume MGB Surgeons = Poorer Outcomes (Not as Bad as Sleeve or RNY)
• More Leaks• More Reflux• More Revisions• MoreMore Like the “Old Loop” Anatomy • LessLess Like Antrectomy & Billroth II Anatomy
Consensus Conference on MGB; Paris Oct 2012“TRICKS AND TRAPS” TRAINING PROGRAM
• Didactic SessionsTalk with the Leading World Experts
• Arrange for “Hands On Surgery” TrainingScrub on casesAssist and Participate in MGB Surgery
• Dr Rutledge & Dr Kular and other MGB experts World Wide
• USA 001-702-714-0011 [email protected]
Irrational Illogical Thinking Decision-Making Errors
• Confirmation Bias (favor information that confirms preconceptions)
• Herd Behavior (group think override rational)
• “Reptilian Brain”Amygdala is part "impulsive," primitive system that triggers emotional override rational thinking
https://www.surveymonkey.com/s/IFSO-MGB-ConsensusConference Or Email [email protected]
PRIMITIVE RESPONSE SYSTEMSMODIFY RISK ASSESSMENT
https://www.surveymonkey.com/s/CCVote Or Email [email protected]
THE REPTILIAN BRAIN:EMOTION & DECISION MAKING
• Rational Logical Thinking:Frontal Lobe
• Amygdala Interferes with the Frontal lobe
• Primitive, Impulsive
• Irrational decision-making
https://www.surveymonkey.com/s/CCVote Or Email [email protected]
IRRATIONAL ILLOGICAL THINKING CONFIRMATION BIAS
• Contrary Evidence =>Maintains or strengthens present beliefs
• Overconfidence in present beliefs
• Poor Decision Making
• Especially Present in Organizations, Military, Political & Social Groups
https://www.surveymonkey.com/s/CCVote Or Email [email protected]
REPTILIAN BRAIN POOR DECISIONSFEAR LEADS TO JUDGMENT ERRORS
• Errors in Risk Assessment
• Death Airplane Crash
• Death Car Crash
• 1 in 10,000 patient / 20 years risk of gastric cancer
• Bowel Obstruction from internal hernia +16% in 15 months!
https://www.surveymonkey.com/s/CCVote Or Email [email protected]
Surgeons Who Fear Gastric Cancer =Don't Know Much About Gastric Cancer
• Surgeons who say MGB = Bad, Because of the “Risk of Cancer”
• Don't know the Risk of Cancer in the General Population
• Don't know the risk of gastric cancer in Billroth II
• Don't Fear the Risk of Bowel Obstruction from internal hernia +16% in 5 years
• Don't Fear Esophageal Cancer after Band & Sleeve
Surgeons Who Fear Gastric Cancer =Don't Know Much About Gastric Cancer
0%
10%
20%
30%
40%
50%
60%
Agree Disagree
Know About Gastric Cancer
43%
57%
I have recently reviewed the literature on gastric cancer and am very knowledgeable about the risk of gastric cancer
Question Answer
H. Pylori Treatment Normalizes Risk of Gastric Cancer in Ulcer Patients.
Agree 100%
The association between H pylori infection and the development of gastric cancer is well established
Agree 100%
Gastric cancer can be prevented by treating H. Pylori, eating a diet of fresh fruit and vegetables and avoiding smoking, alcohol and nitrates in preserved foods
Agree 100%
Question Answer
There are many large scale studies that show no increased risk of gastric cancer after Billroth II:
Disagree 60% !!!
Unoperated Gastric Ulcer patients have double the risk for Gastric Cancer
Agree 100%
There are some studies showing a slight increased risk of gastric cancer 20-30 years after Billroth II. But these patients had the Billroth II overwhelmingly for Ulcer Disease &Ulcer and Gastric Cancer have a common etiology; H. Pylori.
Agree 100%
SURGERYHISTORY OF POOR DECISIONS
JOSEPH LISTER:
AMERICAN SURGEONS DELAYED ADOPTION OF ANTISEPSIS 10 YEARS
REPTILIAN BRAINPOOR DECISION MAKING
• Lister published antisepsis
paper:
• 1867
Dr. Gross; Gross Clinic 1875
(Un) Popularity of the MGB
• Confusion:MGB Not Old Mason Loop Gastric Bypass
• MGB = Antrectomy and BII
• Old Mason Loop = Total Gastrectomy + BII
https://www.surveymonkey.com/s/IFSO-MGB-ConsensusConference Or Email [email protected]
PR.O.A.C.T METHODOLOGY• Pr: Define the Problem• O: Objectives: Criteria for Success• A: Alternatives: Available Options• C: Consequences: Outcomes/Results • T: Tradeoffs: Weigh Pros & Cons• Different Systematic way to make decisions....
https://www.surveymonkey.com/s/IFSO-MGB-ConsensusConference Or Email [email protected]
PR: STATE THE PROBLEM
• Obesity Epidemic
• History of Failure of Bariatric Surgical Procedures
• Selecting the “Ideal / BEST” Bariatric Surgical Procedure
https://www.surveymonkey.com/s/IFSO-MGB-ConsensusConference Or Email [email protected]
PR: Problem Definition:Bariatric Surgery: A HISTORY OF FAILURE
Procedure AssessmentJejuno-ileal Bypass (Failure)Vertical Banded Gastroplasty (Failure)Lap Band (Fail?)RNY Bypass (Fail?)BPD/DS (Fail?)Sleeve: 1-5% Leaks, 60-80% Late GE Reflux, Irreversible, High Rate Weight regain (Fail?)
Sleeve Consensus Meeting?
19 surgeons have shared their data and consensus has been sought on specific points related to sleeve only
Mean 12% acid reflux
Many showing 20% reflux
Many showing 40 % weight loss failure ( < 50 % EWL )
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SUCCESS CRITERIA"IDEAL" WEIGHT LOSS SURGERY
1. Low Risk2. Major Weight Loss3. Easily performed4. Short operative times5. Outpatient or short hospital stay6. Minimal Blood Loss7. No Need for ICU Stay8. Minimal Pain9. Very High Patient Satisfaction10. A Good "Exit Strategy"
O: OBJECTIVES, SUCCESS CRITERIA"IDEAL" WEIGHT LOSS SURGERY
O: OBJECTIVES, SUCCESS CRITERIA"IDEAL" WEIGHT LOSS SURGERY11. Change Behavior & Preferences; Marked Decrease in Hunger
and Increased Satiety12. Minimal Retching and Vomiting 13. Few adhesions or hernias14. Minimal impact on Heart and Lung Function15. Low Failure Rate16. Low Cost17. Short Recovery Time18. Rapid Return to Work19. Low Risk of Pulmonary Embolus20. Durable weight loss
O: OBJECTIVES, SUCCESS CRITERIA"IDEAL" WEIGHT LOSS SURGERY
21. Low Risk of Ulcer22. Fat Malabsorbtion; low cholesterol & CV risk 23. No Plastic Foreign Body 24. Easily Verifiable Results; > 10 years of Results25. Low Risk of Bowel Obstruction26. Based upon sound surgical principles 27. Independent confirmation of results28. Healthy life after surgery29. Supported by LEVEL I Evidence; RCT (Controlled Prospective
Randomized Trial)30. Block “Sweet Eater” Failures
A: ALTERNATIVES
• RNY
• Band
• Sleeve
• MGB
https://www.surveymonkey.com/s/IFSO-MGB-ConsensusConference Or Email [email protected]
MINI-GASTRIC BYPASS
• The Mini-Gastric Bypass1997 – 2011 ; >6,000 pts, 10 yr Data; Multiple Centers, R.C.Trials
• Vertical Gastric Tube(Collis Gastroplasty)
• Gastric Bypass(Billroth II Gastro-jejunostomy)
https://www.surveymonkey.com/s/IFSO-MGB-ConsensusConference Or Email [email protected]
MINI-GASTRIC BYPASSBASED SOUND SURGICAL PRACTICE
• Billroth II Performed over 100 years
• 16,000 Billroth II’sUSA in 2007
• Operation of choice: Trauma, Ulcers, Cancer Stomach etc.
T: TRADEOFFS• Fear of Gastric Cancer \ Bile Reflux• Rational vs. Reptilian Brain Decision Making
STATISTICAL ILLITERACY; "MANY DOCTORS MISUNDERSTAND MEDICAL LITERATURE"
• Example: “In the absence of a Roux limb, the long-term effects of chronic alkaline reflux are unknown.”
• REALLY? Rational vs. Reptilian Brain thinking
• Billroth II >100 years and >1,450 papers on Billroth II
Collins BJ, Miyashita T, Schweitzer M, Magnuson T, Harmon JW., Gastric Bypass; Why Roux-en-Y? A Review of Experimental Data,
Arch Surg. 2007; 142(10):1000-1003.
STATISTICAL ILLITERACY; "MANY DOCTORS MISUNDERSTAND MEDICAL LITERATURE"
• Example:
“In the absence of a Roux limb,
the long-term effects of chronic alkaline reflux are unknown.”
Collins BJ, Miyashita T, Schweitzer M, Magnuson T, Harmon JW., Gastric Bypass; Why Roux-en-Y? A Review of Experimental Data,
Arch Surg. 2007; 142(10):1000-1003.
GASTRIC CANCER RAPIDLY DECLINING
• The incidence of gastric cancer in the United States has
• Decreased four-fold since 1930
• Approximately 7 cases per 100,000 people.
https://www.surveymonkey.com/s/IFSO-MGB-ConsensusConference Or Email [email protected]
BARIATRIC SURGEONS FEAR BILLROTH II;CANCER SURGEONS CHOOSE BILLROTH II
• 1,490 articles on performance of the Billroth II
• General/Trauma/Oncologic surgeons commonly use the Billroth II
• Over 16,000 Billroth II operation performed in USA 2007
• While Bariatric Surgeons Fear the Billroth II General Surgeons use the Billroth II routinely
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BARIATRIC SURGEONS FEAR BILLROTH IIWHAT IS MAGNITUDE OF THE PROBLEM
• Mayo Clinic Study (Example)• 338 Billroth II patients
• Followed 25-years
• 5,635 person-years
• Only 2 Cancers in 5,000+ pt years of Follow Up • Schafer et al, Risk of gastric carcinoma after treatment for benign ulcer disease. N
Engl J Med. 1983 Nov 17;309
BARIATRIC SURGEONS FEAR BILLROTH IIMAGNITUDE OF THE PROBLEM
• Population based study, 338 Billroth II pts
• Followed 25-years
• 5,635 person-years
• Only 2 Cancers Found in 5,000 years• Predicted 2.6 cancers (relative risk 0.8)
Schafer et al, Risk of gastric carcinoma after treatment for benign ulcer disease. N Engl J Med. 1983 Nov 17;309
BARIATRIC SURGEONS FEAR BILLROTH IIMAGNITUDE OF THE PROBLEM
• 338 Billroth II pts, Followed 25-years
• 5,635 person-years
• Only 2 Cancers in 5,000 pt years follow up
• RATE of Gastric Cancer is Declining• 24 - 50% Expected Decrease from 1983
• Future risk ~1 patient / 5,000 pt years
ULCERS INCREASE RISK CANCER
• Meta-analysis: 7 studies Small increased risk 5 studies No Increased Risk
• Studies with increased Risk; Flawed• Billroth II = Surgery Rx Ulcers
• ULCERS increase risk of Gastric Cancer!
• Ulcers and Gastric Cancer Common Etiology =H. Pylori=
ULCERS INCREASE RISK CANCER
•3,078 gastric cancer vs. 89,082 controls•Ulcer increases risk gastric cancer =(relative risk 1.53)=•Same as Increased Risk reported Billroth II •Many other studies confirm these findings: •Ulcer Increases Risk Gastric Cancer•Ulcers & Gastric Cancer:•Common Etiology =H. Pylori=
BARIATRIC SURGEONS FEAR BILLROTH IIGASTROENTEROLOGISTS IGNORE BILLROTH II
• Hundreds of thousands of people with Billroth II’s
• If cancer IS SUCH A BIG RISK…
• Shouldn’t gastroenterologists be looking for these people, screening them with endoscopy?
• No, there is no recommendation for BII follow up screening; Why? THE RISK IS LOW
• 63,000 yrs Follow up 23 cancers = Gen Pop.
RISK OF GASTRIC CANCER AFTER BILLROTH II IS LOW
• Follow-up study of 1000 patients
• 22-30 year follow-up
• 196 endoscopy and biopsy No Cancer of the gastric remnant seen
• Endoscopic screening will be “unrewarding”
• Br J Surg. 1983 Sep;70(9):552-4. Risk of gastric cancer after Billroth II resection for duodenal ulcer. Fischer AB
WHAT CAUSES GASTRIC CANCER?ITS NOT BILLROTH II
• Diets rich in fried, salted, smoked or preserved foods increased cancer risk in many studies.
• Foods contain nitrites and these chemicals can be converted to more harmful compounds (carcinogens) by bacteria in the stomach.
• Diets high in fruit and vegetables protects against Cancer
• Stomach cancer is much more common in smokers and in those with heavy alcohol intake.
• H. Pylori, No H. Pylori No Cancer
DIET AND CANCER PREVENTION
• Avoid ETOH, Tobacco, Processed & Preserved Meats, Salt
• RX H. Pylori, • Eat Fruits and Veggies,
Yogurt and • Drink Green Tea
•Gonzalez CA, Cancer Research, Institut Català d'Oncologia, Av. Gran Via s/n, km 2.7, 08907 L'Hospitalet, Barcelona, Spain.
T: TRADEOFFS FEAR OF GASTRIC CANCER
A Billroth II Probably Makes No Difference
T: TRADEOFFS FEAR OF GASTRIC CANCER
A Billroth II Probably Makes No Difference
Expert Opinions: "May be the Best Operation, I Use It Frequently"
Good, maybe the best form of WLS, I use it often?
May I beg your indulgence: Please consider giving us your learned opinion:https://www.surveymonkey.com/s/IFSO-MGB-ConsensusConference Or Email [email protected]
0%
10%
20%
30%
40%
50%
Band Sleeve RNY MGB
Maybe Best Operation
4%
48%
46%
46%
Expert Opinion: Operation Judged Short and Simple
0%
20%
40%
60%
80%
100%
Band Sleeve RNY MGB
Short Simple Op
89%
51%
11%
47%
Expert Opinion: Failure is "VERY RARE"
0%
10%
20%
30%
40%
50%
Band Sleeve RNY MGB
Failure is Very Rare
0%
16%
37%
42%
Experts Who Once Used the Band and Now Have Stopped Using the Band (38%)
0%
10%
20%
30%
40%
50%
60%
70%
Y N
Stopped Using the Band
38%
62%
Expert Opinions: Patients Routinely Get Major Weight Loss
0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
100%
Band Sleeve RNY MGB
Patients routinely get major weight loss
15%
85%
89% 89%
Expert Opinions: Patients RARELY Regain Their Weight
0%
20%
40%
60%
80%
100%
Band Sleeve RNY MGB
Patients RARELY Regain Their Weight
8%
48%
68%
77%
Expert Opinion: Patients RARELY Suffer Long Term Complications
0%
10%
20%
30%
40%
50%
60%
70%
80%
Band Sleeve RNY MGB
Patients RARELY Suffer Long Term Complications
18%
72%
55%
64%
MGB Experts (>100 MGBs): Patients RARELY Suffer Long Term Complications
0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
100%
Band Sleeve RNY MGB
MGB Experts: Patients RARELY Suffer Long Term Complications
0%
44%
34%
89%
Expert Opinions: Procedure Advocates Reporting "No Leaks"
25%
30%
35%
40%
45%
50%
55%
60%
65%
MGB Sleeve RNY
No Leaks %
61%
48%
38%
No Leaks %
Expert Opinions: Procedure Advocates Reporting a Leak
25%
30%
35%
40%
45%
50%
55%
60%
65%
MGB Sleeve RNY
Surgeons WITH Leaks
39%
52%
62%
Expert Opinion: Revision is Relatively Easy
0%
10%
20%
30%
40%
50%
60%
70%
80%
Band Sleeve RNY MGB
Revision is relatively easy
41%
48%
6%
67%
RNY Band SG MGB1. Low Risk - + - +2. Major Weight Loss + - - ++3. Easily performed - - + + +4. Short operative times - + + +5. Short hospital stay - - + + +6. Minimal Blood Loss - + + +7. No Need for ICU Stay - + + +8. Minimal Pain - + + +9. High Patient Satisfaction - - - +10. A Good "Exit Strategy" - - - + - - +
RNY Band Sleeve MGB11. Decrease Hunger + - + +12. Min Vomiting + + + +13. No Internal hernias - + + +14. Min Heart/Lung - + + +15. Low Failure Rate - - - +16. Low Cost - - - +17. Short Recovery - + + +18. Return to Work - + + +19. Low Risk of PE - + + +20. Durable Weight Loss - - - +
RNY Band SG MGB21. Low Risk of Ulcer - + + -22. Malabsorption of fat + - - +23. No Foreign Body + - + +24. Verifiable Results - - - ++25. Bowel Obstruction - - + + ++26. Sound Surgical + - + +27. Independent confirm - - - ++28. Healthy life - - - ++29. RCT; LEVEL I Evidence - - - ++30. Block Sweet Eater + - - ++
CONCLUSIONS: PR.O.A.C.T.Rational Choice: Mini-Gastric Bypass• Pr: Choice of Obesity Surgery
• O: Objectives “Ideal” Weight Loss Surgery
• A: RNY, Band, Sleeve, MGB
• C: MGB meets almost all objectives/success criteria
• T: Fear of Bile Reflux & Gastric Cancer Not Supported by the Data
• Rational Decision Making: Best Choice; Mini-Gastric Bypass
WHY CRITICS ONLY CARE FOR MGB?• Why do Critics only care about the
Mini-Gastric Bypass?
• 100,000’s of people already have and are living with and are getting the Billroth II every day
• Why haven’t concerned bariatric surgeons stepped forward to stop all general, trauma and oncologic surgeons from performing this Billroth II surgery?
WHY CRITICS ONLY CARE FOR MGB?•Why do Critics only care about the Mini-Gastric Bypass?
•Why haven’t concerned bariatric surgeons stepped forward to start a fund to help suffering Billroth II patients get needed conversions of their surgery to Roux-en-Y?
•Why don’t they write letters to the editor calling for the Billroth II to be declared a operation non-grata?
WHY CRITICS ONLY CARE FOR MGB?• Why do Critics only care about the
Mini-Gastric Bypass?
• Why haven’t concerned bariatric surgeons stepped forward to national funding for lifetime endoscopic screening of Billroth II patients to find dreaded gastric cancers?
• It seems odd doesn’t it?
• There is a simple reason
WHY CRITICS ONLY CARE FOR MGB?• There is a simple reason
• The critics of the MGB do not do those things because they are ...
• Such actions are Not supported by the data
• The Billroth II and the MGB are both good operations
• Published data Does Not support the critics misreading of the medical literature
THE TIDE BEGINS TO TURNTO THE MINI-GASTRIC BYPASS
• “Not too long ago, the bariatric community questioned the role of the mini-gastric bypass and its appropriateness as a durable operation for obesity.”
• The experience of Lee et al. with a large cohort suggests some answers.”
• Michel M. Murr, M.D.
• “The Journal continues to commit to open, spirited, and balanced discussions that are supported by data and withstand the test of common sense.”
• Editorial: Revisional surgery for laparoscopic mini-gastric bypass. Lee WJ, Surg Obes Relat Dis. 2011 Jul-Aug;7(4):486-91
Mini-Gastric Bypass: 9 YEARS LATER! OUT PERFORMS RNY
• New results of the MGB:
• “1,322 patients, 23 (1.7%) had revision Follow-up of 9 years.”
• Excess weight loss 72.1%
• No patient had surgery for internal hernia Revisional surgery for laparoscopic mini-gastric bypass.
Lee WJ, Surg Obes Relat Dis. 2011 Jul-Aug;7(4):486-91
Patient Survey: MGB OUT-PERFORMS BAND & RNY
• Follow up survey of bariatric surgery results in 1,500 patients’ friends, family and acquaintances
• Patient Reported Success in Friends Family:
36% RNY,
24% Band and
93% MGB
EXAMPLE FEAR & DECISION MAKINGSBO VS. GASTRIC CANCER
• Which is more Deadly?
• Gastric Cancer or Small Bowel Obstruction?
• Which is more fearsome?
11+ RNY STUDIES INTERNAL HERNIA BOWEL OBSTRUCTION
• 1 - 16% Internal Hernia /Small Bowel Obstruction
• Follow Up 1-10 years (only 7% at 10 years)
• Note: Dead patients cannot return for follow up
• =15/18 patients, ReOp, failed closure USA=
DEATH AFTER SMALL BOWEL OBSTRUCTION
• 877 patients who underwent 1,007 operations for SBO from 1961 to 1995
• Risk of bowel obstruction increases over time• 52 Deaths 6% Death Rate
• Ann Surg. 2000 April; 231(4), Complications and Death After Surgical Treatment of Small Bowel Obstruction A 35-Year Institutional Experience Fevang et.al., Department of Surgery, University Hospital, University of Bergen, Norway
FEAR AND DECISION MAKINGSBO VS. GASTRIC CANCER
• Which is more Deadly?
• Gastric Cancer or Small Bowel Obstruction?
• Which is more fearsome?
FEAR AND DECISION MAKINGSBO VS. GASTRIC CANCER• 1,000 RNYs, Estimate 20% SBO => 200 operations for
SBO in 5-10 years (? How many more for 20 years?)
FEAR?SBO VS. GASTRIC CANCER• 1,000 RNYs, 20% SBO => 200 operations for SBO in
5-10 years (? How many for 20 years?)• 6% Death Rate => 12 dead before the end of 10 years
from SBO
FEAR?SBO VS. GASTRIC CANCER• 1,000 RNYs, 20% SBO => 200 operations for SBO in
5-10 years (? How many for 20 years?)• 6% Death Rate => 12 dead before the end of 10 years
from SBO• 1,000 MGBs After 20 years possibly increased risk of
cancer of 1 / 1,000
FEAR?SBO VS. GASTRIC CANCER• 1,000 RNYs, 20% SBO => 200 operations for SBO in
5-10 years (? How many for 20 years?)• 6% Death Rate => 12 dead before the end of 10 years
from SBO• 1,000 MGBs After 20 years possibly increased risk of
cancer of 1/1,000• Deaths at 10 years from Gastric Cancer 0.0
FEAR?SBO VS. GASTRIC CANCER• 1,000 RNYs, 20% SBO => 200 operations for SBO in 5-10
years (? How many for 20 years?)• 6% Death Rate => 12 dead before the end of 10 years
from SBO• 1,000 MGBs After 20 years possibly increased risk of
cancer of 1/1,000• Death at 10 years from Gastric Cancer 0.0• Death SBO 12/10 years, Deaths Gastric Cancer 10-20
years 0-1
WHICH DO YOU FEAR?SBO VS. GASTRIC CANCER
• 1,000 RNYs = 200 SBO operations
• Death from RNY SBO 12 deaths / 10 years
• 1,000 MGB’s 0-1 Gastric Cancer @ 20 yrs
• Deaths Gastric Cancer 10-20 years 0-1?
FEAR AND DECISION MAKINGSBO VS. GASTRIC CANCER
• Which is more Deadly?
• Gastric Cancer or Small Bowel Obstruction?
• Which is more fearsome?
FOLLOW UP EFFECT• Unbiased Population based studies => Poor Results of RNY
• Positive Results of RNY reported from RNY centers
• Suffer from “Follow Up Effect”
• Patient Returns to clinic doing well: Greeted Warmly with Great Joy
• Patient Returns to clinic doing poorly: Greeted with anger and disapproval
• Successful pt => Good Follow Up / Failed pt tacitly sent away
• Now; Center reports excellent results; (30%) follow up
• Weight Regain, Band Erosion, Death
• Not Seen, Not Reported