KLERESCA®

SKIN REJUVENATION

SKIN REJUVENATION REIMAGINED

*

* W ith LED light as a control, the treatment delivers approximately a 400% increase in collagen production. These results were documented in-vitro and support findings from in vivo studies based on biopsies9,10.

A new technology that boosts your skin’s natural repair mechanisms1-8

SKIN REJUVENATION REIMAGINED

• Non-invasive biophotonic treatment1, 10

• Designed to rejuvenate your skin1, 9, 10

• Comfortable, with little to no downtime1

• One treatment per week for 4 weeks

• Each treatment takes approximately 30 minutes

• Gel is applied on the affected area and illuminated under Kleresca® blue light for 9 minutes

• After treatment, gel is removed and skin is cleansed and moisturized

KLERESCA® SKIN REJUVENATION TREATMENT5

• Make-up can be applied immediately after

• Male patients should shave the night before

• Please, refrain from using any topical creams or ointments dur the treatment, unless specified by your treating physician

• Inducing collagen production9

• Reducing pore size9

• Eliminating fine lies9

• Reducing signs of scars1,6,9

EFFECT WITHOUT COMPROMISE

• Transient redness after the treatment

• Hyperpigmentation (bronzing of an area of the skin)

• Slight discoloration of hair in some cases where the gel was applied covering facial hair

WHAT YOU MIGHT EXPERIENCE

In the clinical trial, adverse events were transient in nature and did not require any intervention by the investigators

BEFORE AND AFTER

Female patient 3 months post Kleresca® Skin Rejuvenation.

Baseline After 12 weeks

Improvement of crow’s feet and decrease in fine rhytides

BEFORE AND AFTER

Baseline After 12 weeks

Pore size improvement at week 12

Female patient 3 months post Kleresca® Skin Rejuvenation.

BEFORE AND AFTER

Baseline After 12 weeks

Reduction of marionette lines at week 12 due to increase in collagen production

Female patient 3 months post Kleresca® Skin Rejuvenation.

1. Antoniou, C.et al . A multicenter, randomized, split-face clinical trial evaluating the efficacy and safety of chromophore gel-assisted blue light phototherapy for the treatment of acne. 2016; Int J Dermatol, 2016, 55; 1321 – 1328

2. KL-K1005-P001. LEO Pharma – Data on file3. PCL-K1005-001-11. LEO Pharma – Data on file4. In vitro release test. LEO Pharma – Data on file5. Kleresca® Skin Rejuvenation Instruction for Use6. Nikolis, A. et al. An extension of a multicenter, randomized, split-face clinical trial evaluating the efficacy and safety of

chromophore gel-assisted blue light phototherapy for the treatment of acne. Int. J. Dermatol. 2017; Accetped7. Endothelial cell study. LEO Pharma – Data on file.8. SKR1. LEO Pharma – Data on file.9. Nielsen, M.E., et al (2017). Introducing: photobiomodulation by low energy chromophore-induced fluorescent light. Mechanisms

of Photobiomodulation Therapy IV, SPIE Photonics West BIOS, San Francisco, 2017; 28 January – 2 February10. SKR Safety Report. LEO Pharma - Data on file.

References