Kamerow 10-12 ADA Forum Poster - Final.pdf

Kamerow 10-12 ADA Forum Poster - Final.pdf
download Kamerow 10-12 ADA Forum Poster - Final.pdf

of 1

  • date post

  • Category


  • view

  • download


Embed Size (px)

Transcript of Kamerow 10-12 ADA Forum Poster - Final.pdf

Evaluation of Multicomponent Interventions to Enhance Outcomes and Reduce Disparities among Diverse Patient PopulationsMegan A. Lewis, Pamela A. Williams, Jeffrey Brenner, Patria Johnson, Kathy Langwell, Monica Peek, James Walton, Noreen M. Clark, and Douglas Kamerow *1 1 2 3 4 5 6 7 1

AbstractThe Alliance to Reduce Disparities in Diabetes, sponsored by The Merck Company Foundation, is a consortium of five grantees, a National Program Office, and an external evaluator. The Alliance integrates innovative professional and patient education and quality of care improvements aimed at vulnerable patients, and focuses on reducing disparities in diabetes care and enhancing outcomes through clinical and community interventions. Five project sites involving key community stakeholders in reducing disparities are based in Chicago, IL, Camden, NJ, Wind River Indian Reservation, WY, Dallas, TX, and Memphis, TN. Across the Alliance sites a multiracial patient group was enrolled and sites implemented multilevel and multicomponent interventions to enhance patient skills, clinician cultural competencies, and health care systems changes to address disparities and enhance care. Each grantee provided clinical (hemoglobin A1c [HbA1c], blood pressure [BP]) and patient-reported outcomes (diabetes competence, quality of life, resources and supports for self-management, and diabetes self-care behaviors) for program participants to the Alliances external evaluator. Baseline and follow-up clinical data are reported for more than 1,000 patients, with a decrease of mean HbA1c values from 8.5% to 7.9% and a decrease in BP from 132/80 to 129/78, both significant at the p < .001 level. Multivariable regression analysis showed that patients who participated in more than half of the program had greater changes in both HbA1c and BP over time, controlling for age and gender. Analyses of the patient-reported survey measures also showed significant improvements in perceived diabetes competence, resources and supports for self-management, and self-care behaviors. We conclude that multicomponent programs can reduce disparities and improve outcomes for people with diabetes. It combines the strengths of the healthcare system, the strengths of the community, and there havent been a lot of projects like this in [our city]. I think its a positive in terms of doing these collaborations across the five centers and the partnership, which, again, has not traditionally happened. So its fun. Site Co-PI

2. InterventionsAlthough the interventions vary across the programs, the focus is on three core components:

3. Cross-Site Evaluation (continued)Program ParticipantsTable 1 presents the demographic characteristics for program participants who currently have baseline and follow-up measures, and are included in the cohort analysis. The average time between baseline and cohort measures is 1 year. Table 1. Demographic Characteristics of Program Participants in the Cohort Characteristic Cohort Gender Male Female White African American Native American Race/Ethnicity Hispanic Asian/Pacific Other Unknown 1844 N 1,143 417 710 91 300 34 627 16 16 59 345 398 388 Unweighted Percent 100.0 37.0 63.0 8.0 26.3 3.0 54.9 1.4 1.4 5.2 30.5 35.2 34.3

4. Preliminary Results (continued)Table 3. Patient-Reported Measures Aggregated Across All Grantees Outcome Diabetes Competence Resources and Support for Selfmanagement Quality of Life (VR-12) Physical Mental Diabetes Self-care General diet Specific diet Exercise Blood-glucose testing Foot care 4 4 4 4 4 4 4 4 4 4 Baseline Follow-up Baseline Follow-up Baseline Follow-up Baseline Follow-up Baseline Follow-up 3.6 4.5 4.0 4.4 2.8 3.3 4.2 5.0 4.0 5.0 162 162 165 165 166 166 168 168 167 167 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 7.0 0.000 0.000 0.000 0.000 0.000 4 4 4 4 Baseline Follow-up Baseline Follow-up 40.1 41.2 44.6 45.6 167 167 167 167 18.8 18.1 11.5 20.4 59.9 64.4 69.5 69.6 0.090 0.019 Number of Sites 3 3 2 2 Time Baseline Follow-up Baseline Follow-up Mean 5.2 5.9 2.6 2.9 N 126 126 38 38 Min 1.0 1.4 1.0 1.0 Max 7.0 7.0 4.0 4.0 0.004 0.000 t-test (p-value)

5. DiscussionAlthough these five programs are not randomized controlled trials, comparisons of clinical and patient-reported measures from baseline to follow-up show improvements across almost all measures, including both clinical and behavioral outcomes. I think the fact that they were able to go [work out] together and sort of have partners and that they have this resource that was free in the community was really exciting. So it was a really nice example of the education and the social support and the community resources that our project brings together, really helping a couple of these patients become empowered and take control of their health. Site Project Manager This evaluation suggests that the Alliance is demonstrating that diabetes outcomes can be improved and disparities potentially decreased in groups most burdened by diabetes management by using multifocal interventions that include patient, provider, and system components. Analyses specifically comparing racial differences did not emerge as significant. These findings are likely attributable to the fact that the Alliance programs sought to serve low-income and underserved adults with type 2 diabetes regardless of race, although these programs have successfully served a large multi-ethnic and multiracial group of program participants.

Patient Component: Patient education included community, small group, and individual materials, classes, and discussions. Curricula included topics such as the basics of diabetes; food diary instructions and healthy eating tips; physical activity and exercise; goal setting; glucose monitoring; fat and calorie education; HbA1c, BP, and cholesterol education; managing high and low glucose; checking blood sugar levels; smoking and alcohol; long-term complications; and treatment options. The patient classes are diabetes education and then patient/ provider communication around shared decision making. Patients are educated on how to take care of themselves and a lot of that requires what you eat and what you do, which means that they need to be aware of community resources that can help them with eating better and having better physical activity. Site PI Clinician Component: Provider education included cultural competency training and behavioral change education about communicating effectively with patients and facilitating lifestyle improvements. Before I used to focus only on numbers. Now I understand that its not all about that. Those [numbers] are important but also taking into account what the patients are going through in their houses and with their family, it has a great effect, too. Diabetes Health Promoter System Change Component: Diabetes management via systems changes included care coordination, use of diabetes registries, nurse or community health worker participation in care management, enhanced community partnerships, and policy changes. All of these elements focused on improving care for and self-management by patients with diabetes. We reach out as far as like system level, to the community, from the patient and the provider. Its like multifaceted and all of those areas together, like one is no more important than the other, you cant subtract one for another, they all need to work together and thats what were doing. Site Project Manager

6. Next StepsNext steps in the cross-site evaluation include additional data collection, such as a comparison cohort, that will allow us to determine whether disparities in diabetes were reduced. In addition, a final site visit with grantees at the end of their intervention programs will allow us to better understand program process improvements over the course of the initiative that may have helped contribute to program success.


4554 55 or older

Note: VR-12 = Veterans RAND 12 Item Health Survey

1. BackgroundTo address the growing problem of health care disparities in the context of type 2 diabetes in the United States among low-income and underserved adult populations, The Merck Company Foundationthe philanthropic arm of Merck & Co., Inc.launched the Alliance to Reduce Disparities in Diabetes. The Alliance aims to help decrease diabetes disparities and enhance the quality of health care by improving prevention and management services. Through grants to five organizations, The Merck Company Foundation supports comprehensive, multifaceted, community-based programs that address key factors to improve health outcomes for people living with diabetes. The five programs and grantees are:

4. Preliminary ResultsResults for Clinical and Patient-Reported OutcomesFor the participant cohort, we used t-tests and multivariable regression analyses to understand how health and diabetes outcomes changed over time because of program participation. Table 2 presents the descriptive statistics for the baseline and follow-up clinical measures, and indicates significant differences. Both HbA1c and BP improved from baseline to follow-up. Table 3 presents the same information for patient-reported outcomes. All measures show improvement from baseline to followup (p < .05), except for quality of life measured by mental functioning, although there was a trend toward significance for this measure (p < .10). Table 2. Clinical Measures Aggregated Across All Grantees t-test Median (p-value) 8.0 7.4 128/80 123/78 98 97 0.437 0.000 0.000

To further understand the potential impact of the grantee programs on changes over time, we regressed each of the changes in clinical measures on selected characteristics, including age (under 55 years vs. 55 or older), gender (male vs. female), and race (any underrepresented race vs. White), and program participation status (high intensity vs. low intensity). Highintensity progra