Jurnal Reading Retinopati Diabetik Stase Mata

8/18/2019 Jurnal Reading Retinopati Diabetik Stase Mata

1/16

“Proliferative diabetic retinopathy isassociate with microalbuminuria in

patients type 2 diabetes”

Meiki permatasari, S.Ked

Pembimbin ! dr. "ahmad syuhada, M.Kes, Sp.M

#K $

%ournal readin !

K&P'()*&"''( K+)()K S&()" "S P&"*'M)(' -)(*'( 'M)(/0S'1'

'K0+*'S K&1K*&"'( 0()3&"S)*'S M'+'/'4'*) -'(1'"+'MP0( 2567


2/16

)(*"108*)(

• 1iabetic patients with proteinuria orthose on dialyss ussually presentsevere forms of 1", but associationof 1" with early stae of diabeticnephropathy has not been entirelyestablished.


3/16

P0"PS&

*he aim of present study was todetermine if microalbuminuria isassociated with proliferative 1" in

type 2 diabetic patients while takininto account other possible factors


4/16

M&*1&

• ' cross9sectional study

• was conducted on 626: type 2 diabetic patients to determinewhether

• microalbuminuria is associated with proliferative diabeticretinopathy

• in these patients. Patients were evaluated by direct and indirect

• ophthalmoscopy and rouped accordin to the presence orabsence of

• proliferative diabetic retinopathy. *he areement of diabeticretinopathy

• classi;cation performed by ophthalmoscopy and by stereoscopic

• color fundus photoraphs


5/16

8ontinue<

undus e=amination was performed in

all patients by a trained ophthalmoloist usin

direct and indirect ophthalmoscopy

throuh dilated pupils. "etinopathy was classi;ed

as non9proliferative #includin absentsins of 1" or sins of non9proliferative

1", i.e., microaneurysms, hemorrhae, hard

e=udates$ or proliferative #newly formed

blood vessels and>or rowth of ;brous tissueinto the vitreous cavity$. Patients with

panphotocoaulation

were classi;ed as presentin

proliferative 1".


6/16

8ontinue<

*he severity of 1"

was raded based on the worst eye. )n 2

patients in whom the presence of media

opacities due to vitreous hemorrhae #6 patient$,

and cataract #6 patient$ prevented fundoscopy

in one eye, the contralateral eye

was used to classify 1". (o patient was

e=cluded as a result of unreadable fundoscopy

in both eyes. *he dianosis of proliferative1" based on fundoscopy performed

by the ophthalmoloists was used to classify

the patients


7/16

8ontinue..

• 1emoraphic information, smokinhistory, anthropometric and bloodpressure measurements, lycemic

and lipid pro;le, and urinary albuminwere evaluated.


8/16

8linical and laboratory evaluation

• se=

• 'e

• 1iabetes duration

• Smokin habit

• Metabolic syndrome

• )nsuline use

• 0se of '8& inhibitor

• /ypertension

• 1iabetic (eprophati

• Microalbuminuria

• Macroalbuminuria

• 1ialisys

• Systolic blood pressure

• 1iastolic blood pressure

•

-ody mass inde=• ?aist9to9hip ratio

• lycosylated hemolobin

• *otal cholesterol

• /1+

• +1+

• *rilyserides

• Serum creatinin


9/16

"&S0+*

*able 6. clinical and laboratory characteristicsof 626: type 2 diabetic patients with and

without proliferative diabetic retinopathy


10/16

Withproliferativediabetic

retinopathy

Withoutproliferat

ivediabeticretinopha

ty

P

(umber of sub@ectsMale se='e #years$1iabetes duration #years$Smokin habit

Metabolic syndrome)nsuline use A0se of '8& inhibitors/ypertension1iabetic nephropathyMicroalbuminuria

Macroalbuminuria1ialysisSistolic blood pressure#mm/$1iastolic blood pressure#mm/$

-ody mass inde= #k>m2$?aist to hi ratio

22C6D: #EF.5B$75.D A F.F6E.7 A G.ED5 #6D,2B$

25F #F2.2B$6:D #7D.5B$626 #ED.6B$6CF #CG.CB$6G5 #CF.DB$:C #25.CB$

76 #27.GB$C2 #D6.CB$

6:C.2 A 22.CGE.7 A 6:.D2C.: A :.C5.FE A 5.5G

G.72 A 6.G:

FGCDF2

#DF.CB$EG.6 A65.:

65.6 AG.625D

#25.7B$G57

#G6.CB$

D6F#D2.DB$

D77#DC6B$

7:F#7E.GB$

D:CDE,2B

H5.5565.55E

H5.5565.567

H5.556

H5.556H5.556H5.556H5.5565.:67

H5.556

H5.5565.5525.D5C

H5.5565.D725.G7:

5.G7:


11/16

Withproliferativediabetic

retinopathy

Withoutproliferativediabetic

retinopathy

P

*otal cholesterol

#m>d+$/1+ #m>d+$+1+ #m>d+$ *rilycerides #m>d+$Serum creatinine#m>d+$

262.C A E:.6

:2.E A 66.76:D.6 A E:.6

6E5.7 #ED.69F5D.:$6.:G A 6.6:

262.C A E:.5

:7.: A 66.56DF.2 A DG.C6E5.C #27.79

6:C5.5$5.FC A 5.D2

5.G7:

5.5:25.25G5.FCC

H5.556


12/16

M0+*)3'")'*& '('+4S)S

“table 2. multiple loistic

reression analysisI


13/16


14/16

• *o evaluate the association ofmicroalbuminuria with proliferative 1",patients with macroalbuminura #(J6EC$

and patients on dialysis #(JF6$ weree=cluded from reression model #on table2$

• Microalbuminuria #"J D.D, FEB 8)J 6.E79

7.FG, PJ 5.552$• )ts remained associated with proliferative

diabetic retinophaty


15/16

8(8+0S)(

• *ype 2 diabetic patients withproliferative diabetic retinopathymore often presented renal

involvement, includin urinaryalbumin e=cretion within themicroalbuminuria rane

• *herefore, all patients withproliferative diabetic retinophatyshould undero an evaluation of

renal function includin urinary


16/16

* / ' ( K 4 0

Jurnal Reading Retinopati Diabetik Stase Mata

Documents

Transcript of Jurnal Reading Retinopati Diabetik Stase Mata