June 26– July 1, 2010 June 26– July 1, 2010 •• Gothenburg, …emilie/programme.pdf · June...

www.febs2010.org

Programme

June 26– July 1, 2010 • Gothenburg, SwedenJune 26– July 1, 2010 • Gothenburg, Sweden

Welcome to 35th FEBS Congress 2010. For the first time a FEBS Congress is organised jointly by two FEBS Constituent Societies. Your hosts are the Swedish Society for Biochemistry and Molecular Biology and the Norwegian Biochemical Society. We are very grateful to our colleagues from the Baltic Countries Latvia, Lithuania and Estonia as well as Poland, Finland and Denmark, who all supported us in our task.

FEBS Congresses are showcases of the advances in the molecular bio and medical sciences. We have arranged for – as we believe – an attractive and exciting scientific pro-gramme that reflects the most recent advances in molecular biology and biochemistry. More than 140 invited speakers will present their research, among them four Nobel Laureates, nine additional plenary speakers and many further top scientists. We are also proud that one third of our speakers are women (a proportion twice as high as that of women among professors in Europe).

At the same time FEBS Congresses play important roles in networking between scientists from Europe and the whole world. Importantly, FEBS Congresses also serve the purpose of training young scientists and integrating them into the larger scientific community. We are dedicated to make 35th FEBS Congress 2010 a forum for young scientists to interact with peers in the field. The Young Scientist Forum is dedicated to this purpose but also the main Congress will encompass many relevant activities, such as for instance the speaker’s corners.

Göteborg/Gothenburg is a most effective congress city where everything is truly in walking distance – the congress centre is located in the heart of the city. Our efficient Congress organisation will allow you to focus on the scientific pro-gramme and interact with colleagues and young researchers. Gothenburg is a lively, friendly and open city with many attractions. 35th FEBS Congress 2010 starts on the midsum-mer weekend, the most important celebration in the Nordic countries. Daylight almost around the clock! These attributes together with the open and friendly atmosphere will make sure that scientific interaction and communication will thrive at 35th FEBS Congress 2010!

Welcome to

We do our best to make 35th FEBS Congress 2010 a memorable Nordic experience.

For the organising committeeStefan Hohmann, University of Gothenburg (Chairman SFBM)Winnie Eskild, University of Oslo (Chairperson NBS)

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Table of contents

Welcome letter 3

Committees 5

Sponsors and exhibitors 6

Key information 8

Social programme and tours 11

Poster presentations 12

Programme outline 14

Plenary lectures 17

Detailed programme 18

Venue floorplan 32

DESIGN: N.FORM, COVERPHOTOS: © 2005 CLAES AXSTÅL, BJÖRN LARSSON ROSVALL, PRINT: INFORMTRYCKET, 2010

Congress secretariat: Congrex Sweden ABBox 5078, SE 402 22 Göteborg, Sweden

E-mail: [email protected]: +46 31 708 60 25

June 26 – July 1, 2010 • Gothenburg, Sweden

Committees

Local organising committeeStefan Hohmann (chair), Winnie Eskild (co-chair), Bengt Nordén, Catharina Hiort, Claes Gustafsson, Erik Boye, Gunnar C. Hansson, Jan Rydström, Jens Lagerstedt, Jens Nielsen, Karin Lindkvist, Marija Cvijovic, Martin Lidell, Maria Enge, Per Elias, Per Sunnerhagen, Richard Neutze, Sven-Olof Olofsson, Therese Jacobson.

YSF organising committeeErta Kalanxhi, Madelene Palmgren, Malin Johansson, Urszula Kosinska Eriksson.

Nordic programme committeeAnna Blom, Bengt Persson, Bertil Andersson, Britt Marie Sjöberg, Carl Tryggvasson, Carl-Henrik Heldin, Cecilia Holm, Cecilia Hägerhäll, Christer Jansson, Claes Gustafsson, Dan Hultmark, Dick Heinegård, Elisabet Sauer-Eriksson, Elzbieta Glaser, Geir Slupphaug, Gunnar Bjursell, Gunnar von Heijne, Göran Hansson, Hans Jörnvall, Harald Stenmark, Jaak Järv, Katri Niemi, Kjetil Tasken, Lars Hederstedt, Lars Thelander, Lars Wieslander, Leif Bülow, Lena Kjellén, Lorenz Poellinger, Magnus Ingelman-Sundberg, Marc Baumann, Mats Hansson, Måns Ehrenberg, Nils Göran Larsson, Ove Nilsson, Peter Brzezinski, Sara Linse, Slawomir Pikula, Staffan Eriksson, Stefan Björklund, Stefan Ståhl, Stein Ove Døskeland, Steinar Johansen, Sven Enerbäck, Thomas Nyström, Torleif Härd, Tuula Kallunki, Ulf Landegren, Vincent Eijsink, Ylva Engström.

International advisory committeeAaron Ciechanover, Bengt Samuelsson, Claudina Pousadas, Fotis Kafatos, Israel Pecht, Julio Celis, Karl Kuchler, Saskia van der Vies, Tim Hunt.

Professional congress organiserCongrex Sweden AB [email protected]

FEBS executive committeeSecretary General Professor Israel Pecht, Weizmann Institute, Rehovot, ISRAEL

Treasurer Professor John Mowbray, University College, London, UK

Chairman Professor Emmanuel Fragoulis, University of Athens, GREECE

Vice Chairman Professor Tomas Zima, Charles University, Prague, CZECH REPUBLIC

Congress Counsellor Professor Adam Szewczyk, The Nencki Institute of Experimental Biology, Warsaw, POLAND

Chairman Advanced Courses Committee Professor Karl Kuchler, Medical University Vienna, AUSTRIA

Chairman Science and Society Committee Professor Giorgio Semenza, ZOLLIKON, SWITZERLAND

Chairman Fellowships Committee Professor Maciej Nalecz, UNESCO, Paris, FRANCE

Chairman Publications Committee Professor Félix M. Goni, Universidad del Pais Vasco, Laioa, SPAIN

Chairman Education Committee Professor Gül Güner Akdogan, Dokuz Eylül University, TURKEY

Chairman YSF (Young Scientists’ Forum) Dr. Daniela Corda, National Research Council, Napoli, ITALY

Chairman WISE (Women in Science) Professor Ruth H. Paulssen, University of Tromsø, NORWAY

Chairman of the Working Group on Assistance to Central & Eastern Europe (WOGCEE) Professor Mathias Sprinzl, Universität Bayreuth, GERMANY

Contact detailsFEBS2010 Organising committeec/o Prof. Stefan HohmannCell and Molecular BiologyUniversity of GothenburgBox 462SE-405 30 Göteborg, Sweden

http://www.febs2010.org

Congrex Sweden ABRef: FEBS 2010Box 5078402 22 GöteborgSweden

Fax: +46 [email protected]

Göteborg Convention Centre.

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June 26– July 1, 2010 • Gothenburg, Sweden

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Sponsors

www.enzolifesciences.com

Exhibitors

Main sponsor

Silver sponsor

Bronze sponsors

Other sponsors


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Key informationA – Z

Airport busLeaves from Landvetter airport to the city centre every 15 min. and takes approximately 20 min. The first stop (Korsvägen) is in front of the conference center. A return ticket is SEK 150.

BadgesEach participant will receive a name badge upon registration. For security reasons all participants are requested to wear their badge during all the Congress activities and social events.

BanksBanks are open between 09.30 and 15.00 on weekdays. Some banks in central Göteborg are open between 09.00 and 17.00.

ClimateFor weather forecast please visit http://www.smhi.se/en

CurrencyThe official currency is Swedish Krona (SEK).USD 1 = SEK 7,82 (June 2010)EUR 1 = SEK 9,62 (June 2010)

Cash machines (bankomat) are common and accept major credit and debit cards.

Credit cards is accepted almost everywhere. You can use the card on buses, trams, taxi’s and shopping. The chip and pin is the common method. Cash machines (bankomat) are common and takes major credit and debit cards. They can be found in the main shopping centres, the airport and in main streets such as Kungsportsavenyn. Forex is the largest foreign exchange company located at the airport, Kungsportsavenyn 22, the Central Station, Nordstan Shopping Centre and Kungsports platsen.

DisclaimerThe Organising Committee and Congrex Sweden AB accept no liability for injuries/losses of whatever nature incurred by partic-ipants and/or accompanying persons, nor loss of, or damage to, their luggage and/or personal belongings.

ElectricitySweden use 220V AC, 50Hz. Laptops from US using only 110V will need a transformer.

Emergency numberTo call ambulance, police or fire brigade, simply call 112.Main police station, +46 (0) 31 114 14 (24 hours)

Internet accessWiFi will be available at the Congress Centre for all participants attending the Congress.

LanguageThe official language of the Congress is English (no translation facilities will be provided).

Speakers/PresentationsAll speakers are asked to hand in their presentation on a CD or a USB stick at the speaker desk, located opposite the registra-tion desk in the Congress foyer at Svenska Mässan. Computer (PC) and power point projection will be available in all session halls.

Tickets trams and busesThere are several ways to buy tickets. In the area of Göteborg, Mölndal and Partille, you cannot buy tickets from the driver. Instead you need to buy your ticket from newsagents such as Pressbyrån, 7-Eleven or anywhere displaying the Västtrafik sign. You can also buy tickets by text message (if you have a Swedish mobile phone operator) and via credit card on board (one way).

If you are going to travel several times you can by a short-term top-up card. This card enables you to travel wherever you want within specified areas, and as much as you want, within one or three 24-hour periods. They are valid on all Västtrafik vehicles, including all trains except the X2000.

For more information on trams and buses please visit www.vasttrafik.se.

TippingTen per cent of the bill or taxi fare is the usual and appreciated.

MealsCoffee and lunch are included in the Registration fee and will be served in the Exhibition hall during the Congress.

Medical servicesEmergency healthcare

Capio Axess AkutenSödra Allégatan 6, +46 (0) 31 425 00 50 www.capioaxessakuten.se

CityAkutenNordstadstorget 6, +46 (0) 31 10 10 10www.cityakuten.se

Emergency Dental care

Tandvården GöteborgAkuttandvårdenOdinsgatan 10+46 (0)31 80 78 00

MessagesA message board will be located in the registration area. You can post your message here.

On site registration in GöteborgOn site registration will start on Saturday, 26 June at 12.00–18.30 hrs and will then be open during congress hours.

The registration desk and congress secretariat are located at Svenska Mässan, Entrance 8, Mässans gata 8 in Gothenburg.

The registration fee for participants includes: congress bag, congress materials, abstract book, daily coffee/tea, lunches, welcome reception and entrance to the poster/exhibition area.

Poster exhibitionThe poster exhibition will be placed in direct connection to the conference rooms and the exhibition area. Your poster should be on display throughout the Congress.

Programme changesThe organisers cannot assume liability for any changes in the programme due to external or unforeseen circumstances.

ShopsMost Swedish shops open between 9.00 and 10.00 (many grocery stores open at 7.00) and close between 18.00 and 20.00. There is usually no lunch break. Shops in the historical centre are also open during the weekend. Shopping centres are usually open during the weekend and some shops and restaurant Offer 24 hour service. Commonly, most Swedish shops and service providers accept major credit cards (e.g. VISA, Euro card/MasterCard, American Express).

Tourist informationTourist information can be found in the following locations:

Main officeKungsportsplatsen2, +46 (0) 31 61 25 00, www.gothenburg.com

Bransch officeNordstan Shopping Centre, +46 (0) 31 61 25 00

TransportationTaxiWe recommend that you use one of the following taxi companies:

Taxi Göteborg +46 (0) 31-65 00 00 VIP-taxi +46 (0) 31-27 16 11Taxi kurir +46 (0) 31-27 27 27

Do not use taxis that lack clear labelling and that approach you in late evenings.

Travellers with disabilitiesMost hotels have good disabled facilities, with top-end estab-lishments providing access to all areas, including swimming pools and spa facilities. Public transports poses few problems but most trams have often one carriage which is low enough for wheel chairs.

Venue

Svenska MässanThe Swedish Exhibition & Congress Centre Mässans gata 20 SE-412 51 Göteborg


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Social programme and toursSocial programme

Welcome reception – Opening mixerDate: Saturday June 26, at 18.00 hrs. Location: Svenska Mässan, Göteborg The Welcome Reception is free of charge but please indicate upon registration if you will attend in order to guarantee your place. Finger food and one glass of wine/bear will be served.

Social dinner – Midsummer partyDate: Tuesday June 29, at 19.30 hrs. Location: Restaurant Trädgår’n, Göteborg All delegates are invited to join us for an evening with entertainment and a traditional Swedish Midsummer buffet at Restaurant Trädgår’n in the city centre of Göteborg. Price per person: 380 SEK (sign up for the dinner when registering for the Congress)

Monday 28th June 2010, 10.00 – 12.00 hrsMeeting Point: The Swedish Exhibition & Congress Centre, entrance 8

Gothenburg City Tour by bus – 2 hoursThe guests will be picked up at the Congress Centre for a guided tour in the area ofGothenburg, the harbour, the old and new city and many other interesting places.Explore Gothenburg and see the city’s most interesting attractions. The tour begins at Gustav Adolfs Torg square were we find out more about the origins of the city and the importance of the canals to Gothenburg as a trading city. We continue down to the water to look at our beautiful Opera House. Then we travel westwards along the harbor to Klippan cultural reserve with its interesting history, through the old Majorna workers’ quarters and Masthugget where the harbor workers and sailors used to live with their families.

We arrive back in the city centre via Gothenburg’s lung, Slottsskogen park and the trendy Linnéstaden district. Now it’s time to take in the sights and sound of fashionable Avenyn and see Carl Milles’ famous statue of Poseidon up on Götaplatsen square.Minimum number of participants: 25 Price per person: SEK 300 (approx. EUR 30).Includes: Coach, Guide and VAT

Tuesday 29th June 2010, 12.00 – 15.00 hrsMeeting Point: The Swedish Exhibition & Congress Centre, entrance 8

Vikings – 3 hoursThe coach departs from the convention centre to drive you back in time. The trip will take approx. 40 minutes, but that will be just the time you need to enter the 900th century. The staff at the Viking House welcomes you dressed in the clothes of the Viking age. You will get a guided tour around the surroundings, hearing the history of the Viking life. Games, music and woodcraft will get you in the Viking mood and give you an experience you never will forget.

Coffee will be served in the café and afterwards the coach will drive you back to civilisation and the year 2010.Minimum number of participants: 25 Price per person: SEK 700 (approx. EUR 70)Includes: – Coach

– Guide – Guided tour – Possibility to try some Viking games and dressing in contemporary clothing – Coffee and cake (please note this will be served in the cafeteria and not in the Viking house) – VAT

You are most welcome to sign up for the events above at the Registration desk!

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200 V - 37 minutes

300 V - 22 minutes

400 V - 12 minutes

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Poster exhibition

The poster exhibition is placed in direct connection to the conference rooms and the exhibition area.All accepted poster abstracts have received their poster number in the notification email. Please mount your poster to the

assigned poster board marked with your poster number. Poster mounting material for the poster boards will be provided in the exhibition area.

You are asked to mount your poster on June 26 from 12.00. The posters will be on display throughout the conference.Make sure to remove all poster-mounting materials from the board after the Congress. The Congress staff will remove

posters not taken down on time. However, the Congress Organisers cannot ensure any further responsibility for the material.Poster presenters are to be present at their poster board during assigned time slots, please see Detailed Programme.

Poster discussion sessionsPoster sessions for short oral presentations are located in G2, G3 and G4. Please see below the schedule for Poster discussion sessions.

All speakers are asked to hand in their presentation, three power-point slides, on a USB stick at the speaker desk, located opposite the registration desk in the Congress foyer at Svenska Mässan. Computer (PC) and power point projection will be available in all session halls.

Poster discussion session titlesPoster discussion session titles Posters

A1 Ageing A1.04 A1.06 A1.07 A1.09 A1.10 A1.12 A1.15 A1.18 A1.19 A1.24 YSF-51

A2 Molecular immunology A2.05 A2.06 A2.12 A2.16 A2.17 A2.21 A2.34 A2.39 A2.42 A2.45 A2.50 YSF-21

A3 Metabolic diseases A3.11 A3.22 A3.32 A3.63 A3.69 A3.71 A3.73 A3.81 B1.36 B4.71 B4.72

A4 Neurobiology A4.12 A4.13 A4.20 A4.24 A4.25 A4.26 A4.29 A4.36 A4.37 A4.39 A4.41 A4.48

A5 Infectious diseases A5.07 A5.17 A5.55 A5.57 A5.58 A5.66 A5.67 A5.74 A5.76 A5.79 A5.80 YSF-18

B1 Metabolic networks B1.01 B1.09 B1.11 B1.17 B1.18 B1.19 B1.20 B1.24 B1.25 B1.26 B1.28 B1.33

B2 Signal transduction B2.04 B2.05 B2.25 B2.30 B2.41 B2.46 B2.55 B2.71 B2.89 B2.93 B2.99 B2.111

B3 Global networks A5.63 B2.32 B2.85 B2.86 B3.02 B3.03 B3.05 B3.07 B3.12 B3.13 YSF-20

B4 Gene regulation B4.07 B4.19 B4.24 B4.32 B4.44 B4.49 B4.51 B4.54 B4.66 B4.69 D4.07 YSF-121

B5 Regulation of protein function B5.19 B5.28 B5.32 B5.47 B5.50 B5.53 B5.60 B5.62 B5.79 YSF-37 YSF-50 YSF-73

C1,C5 Molecular machines and energy transduction

C1.01 C1.06 C1.07 C1.18 C1.20 C5.01 C5.04 YSF-05 YSF-42 YSF-75 YSF-77 YSF-116

C2,C4 Membrane transport Biological cycles

B2.51 B2.88 C4.13 C4.23 C4.27 C4.28 C4.34 YSF-62 YSF-79 YSF-83 YSF-86 YSF-122

C3 Extracellualr structures C1.23 C3.03 C3.04 C3.05 C3.09 C3.13 C3.15 C3.17 C3.23 C3.25 YSF-43 YSF-76

D1,D3-D5 Cellular Compartments C4.33 D1.01 D1.02 D1.09 D3.04 D3.06 D5.03 D5.07 YSF-04 YSF-13 YSF-14 YSF-80 YSF-103

D2 Mitochondria D2.01 D2.07 D2.08 D2.12 D2.18 D2.21 D2.22 D2.24 YSF-22 YSF-39 YSF-71 YSF-125

E1 Synthetic biology E1.01 E1.02 E1.06 E1.08 E1.11 E1.19 E1.20 E1.24 E1.29 YSF-74 YSF-89

E2 Molecualr recognition B2.96 E2.01 E2.03 E2.04 E2.06 E2.11 E2.12 E2.14 E2.16 E2.19 E2.20 E2.25

E3 Design of macromolecules E3.09 E3.11 E3.12 E3.14 E3.16 E3.18 E3.19 YSF-44 YSF-60 YSF-68 YSF-81 YSF-117

E4 Folding E4.03 E4.11 E4.13 E4.18 E4.22 E4.23 E4.24 E4.25 E4.26 E4.27 E4.29 E5.08

E5 Catalytic mechanisms E5.05 E5.15 E5.17 E5.20 E5.23 E5.24 E5.25 E5.28 E5.34 E5.36 E5.42 E5.50

Sunday, June 27 Hall Session 13.00 Session 14.15

G2 A1 D1,3-5

G3 B1 E1

G4 C1,5 A2

Monday, June 28 Hall Session 13.00 Session 14.15

G3 C2,4 E2

G4 B2 D2

Tuesday, June 29 Hall Session 13.00 Session 14.15

G2 A3 E3

G3 B3 A4

G4 C3 B4

Wednesday, June 30 Hall Session 13.00 Session 14.15

G3 A5 E5

G4 E4 B5

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08.30–11.00

11.00–11.30

11.30–12.30

12.30–13.00

13.00–15.30

15.30–17.00

17.15–19.15

19.30–23.00

08.30–11.00

11.00–11.30

11.30–12.30

12.30–13.00

13.00–15.30

15.30–17.00

17.15–19.15

19.30–23.00

Sunday, June 27Symposium A

Molecules in Health and DiseaseA1 – Ageing, Congress Hall

Symposium B

Molecular NetworksB1 – Metabolic networks, Hall G3

Symposium C

Molecules at WorkC1 – Molecular Machines, Hall G4

Symposium D

Cellular CompartmentsD1 – Secretory pathways, Hall G2

Symposium E

Biomolecular Design and FunctionE1 – Synthetic Biology, Hall J1

Coffee Break

Plenary LectureEMBO Lecture, Congress HallUri Alon

Lunch Service, Hall H

Poster exhibition and discussions Hall H, G2, G3, G4

Speakers corner, C-Balkongen

Activities by FEBS working groupsScience and Society, Hall J1Biofuels

Technology Workshops(3 parallell sessions)• Protein expression, Hall G2• Life cell imaging, Hall G3• Bioinformatics, Hall G4

Plenary LecturesNobel Laureate Lecture, Congress HallJohn Walker

Bücher Lecture, Congress HallSvante Pääbo

Evening eventsFEBS dinner, Blomstermåla, Särö (on invitation)

Saturday, June 26

Registration12.00–18.30

Opening speeches16.30–17.00Congress Hall

Nobel Laureate Lecture, Congress Hall Roger Tsien17.00–18.00

Opening mixer18.00–20.00, Hall H

Monday, June 28Symposium A

Molecules in Health and DiseaseA2 – Molecular Immunology,Congress Hall

Symposium B

Molecular NetworksB2 – Signal Transduction, Hall G3

Symposium C

Molecules at WorkC2 – Biological Cycles, Hall G4

Symposium D

Cellular CompartmentsD2 – Mitochondria, Hall G2

Symposium E

Biomolecular Design and FunctionE2 – Molecular Recognition, Hall J1

Coffee Break

Plenary LectureIUBMB Lecture, Congress HallSusan Lindquist


Poster exhibition and discussionsHall H, G3, G4


Activities by FEBS working groupsEducation, Hall J1Research, Teaching, Learning

Young Scientist Forum, Hall G2Scientific Careers13.30–15.00

Research-Oriented Education at High Schools, Hall J115.40–18.00

Technology Workshops(3 parallell sessions)• Proteomics technologies, Hall G3• Metabolomics, Hall G2• Dynamic modelling, Hall G4

Plenary LecturesNobel Laureate Lecture, Congress HallElizabeth Blackburn

Special event, Congress HallUri Alon (and his guitarr)

Tuesday, June 29Symposium A

Molecules in Health and DiseaseA3 – Metabolic Diseases, Congress Hall

Symposium B

Molecular NetworksB3 – Global Networks, Hall G3

Symposium C

Molecules at WorkC3 – Extracellular structures, Hall J1

Symposium D

Cellular CompartmentsD3 – Endocytosis, Hall G2

Symposium E

Biomolecular Design and FunctionE3 – Design of Macromolecules, Hall G4

Coffee Break

Plenary LectureKREBS Medal Lecture, Congress HallHarald Stenmark


Poster exhibition and discussionsHall H, G2, G3, G4


Tutorials and Events & Corporate SeminarsNMR and Biology – In Interaction, Congress Hall

Activities by FEBS working groupsEducation, Hall J1Practical Systems Biology

Technology Workshops(3 parallell sessions)• Protein interactions, Hall G3• Lipidomics, Hall G2• Applying sequencing technologies,

Hall G4

Plenary LecturesAward Lectures, Congress HallMercedes Munkonda, Hideo Iwai

Svedberg 2010 Lecture, Congress HallPer Jemth

Evening eventsMidsummer party, Trädgårdsföreningen(sep. payment)

Wednesday, June 30Symposium A

Molecules in Health and DiseaseA4 – Neurobiology, Hall G3

Symposium B

Molecular NetworksB4 – Gene regulation, Congress Hall

Symposium C

Molecules at WorkC4 – Membrane Transport, Hall G4

Symposium D

Cellular CompartmentsD4 – Nucleus, Hall G2

Symposium E

Biomolecular Design and FunctionE4 – Folding, Hall J1

Coffee Break

Plenary LectureDATTA Medal Lecture, Congress HallJuleen Zierath


Poster exhibition and discussionsHall H, G3, G4


Tutorials and Events & Corporate SeminarsDatabase taster (by the EBI), Halll G2

Activities by FEBS working groupsWomen in Science, Gender in Science, Hall J1

Technology Workshops(3 parallell sessions)• Protein structures, Hall G3• Molecular imaging, Hall G2• Network modelling, Hall G4

Plenary LectureWomen in Science Award, Congress HallIngrid Grummt

Thursday, July 1Symposium A

Molecules in Health and DiseaseA5 – Infectious Diseases, Congress Hall

Symposium B

Molecular NetworksB5 – Regulation of protein function,Hall G3

Symposium C

Molecules at WorkC5 – Energy transduction, Hall G2

Symposium D

Cellular CompartmentsD5 – Chloroplasts, Hall G4

Symposium E

Biomolecular Design and FunctionE5 – Catalytic Mechanisms, Hall J1

Coffee Break

Plenary LectureNobel Laureate Lecture, Congress HallVenki Ramakrishnan

Closing ceremony12.30–13.00Congress Hall

FEBS Council meeting, Hall G4continues July 2, (on invitation only)

FEBS2010 Congress programme outline


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The FEBS Letters Awardis given to the author of the mostoutstanding research letter published inthe previous calendar year. The awardeemust be the corresponding author of theletter and be aged 40 years or younger atthe time of manuscript acceptance.

The FEBS Journal Prize is awarded to the graduate student oryoung post-doctoral research worker (no more than 3 years from the time ofaward of the PhD degree when the paperis submitted) who is the first author of apaper that is judged to be the best inFEBS Journal during the calendar year.

Details at:www.febsletters.org/content/youngscientist

Details at:www.febsjournal.org/young.asp

Annual Awards for

€10,000 prizesyoung scientists

35th FEBS Congress – Plenary speakers

Plenary speaker Lecture Time Hall Title Affiliation

Roger Tsien Nobel Laureate Lecture June 2617.00

Congress hall Breeding and building molecules to spy on cells and tumors

Department of Chemistry and Biochemistry, University of California San Diego

Uri Alon EMBO Lecture June 2711.30

Congress hall Design principles of biological circuits Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel

John Walker Nobel Laureate Lecture June 2717.15

Congress hall The mechanism and regulation of F-ATPases

MRC Mitochondrial Biology Unit, Cambridge, UK

Svante Pääbo Bücher Lecture June 2718.15

Congress hall Analyses of pleistocene genomes Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany

Susan Lindquist IUBMB Lecture June 2811.30

Congress hall Protein folding and inheritance of environmentally acquired characteristics

Whitehead Institute for Biomedical Research, MIT, Cambridge MA

Elizabeth Blackburn Nobel Laureate Lecture June 2817.15

Congress hall Telomeres and telomerases Department of Biochemistry and Biophysics, University of California San Fransisco, San Fransisco, USA

Harald Stenmark Krebs Medal Lecture June 2911.30

Congress hall How a lipid mediates tumour suppression Centre for Cancer Biomedicine, University of Oslo and Department of Biochemistry, Institute for Cancer Research, the Norwegian Radium Hospital, Montebello, Norway

Mercedes Munkonda FEBS Journal Prize June 2917.15

Congress hall A monoclonal antibody as the first specific inhibitor of human NTPDase3

Institute of Cardiology and Pneumology, Laval University, Québec, Canada

Hideo Iwai FEBS Letters Award June 2917.45

Congress hall Structural basis for the design of a new split intein suitable for site-specific chemical modification

Institute of Biotechnology, University of Helsinki, Finland

Per Jemth Svedberg Lecture 2010 June 2918.15

Congress hall Allosteric pathways in protein domains: sequence versus topology

Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden

Juleen Zierath Datta Medal Lecture June 3011.30

Congress hall Gene/Environment influence on skeletal muscle insulin sensitivity in Type 2 Diabetic patients

Karolinska Institutet, Clinical Integrative Physiology, Stockholm, Sweden

Ingrid Grummt FEBS/EMBO Women in Science Award Lecture

June 3017.15

Congress hall Wisely chosen paths: Regulation of ribosomal RNA synthesis

Division of Molecular Biology of the Cell II, German Cancer Research Center, DKFZ- ZMBH Alliance, Heidelberg, Germany

Venki Ramakrishnan Nobel Laureate Lecture July 111.30

Congress hall What we have learned from structures of the ribosome

Structural Studies Division, MRC Laboratory of Molecular Biology, Cambridge, UK

Plenary lectures


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35th FEBS Congress – FEBS2010 – Detailed Programme

Saturday, June 26, 2010

16.30–20.00 Congress Hall Opening 35th FEBS Congress

Chairperson: Stefan Hohmann (Göteborg)

16.30 Stefan Hohmann Opening speech Chairman, FEBS2010 Organising Committee, Göteborg

Winnie Eskild Opening speech Co-chair, FEBS2010 Organising Committee, Olso

Emmanuel G. Fragoulis Opening speech FEBS Chairman of the Executive Committee, Athens

Israel Pecht Opening speech FEBS Secretary General, Rehovot

17.00 Nobel Laureate Lecture

Chairperson: Gunnar von Heijne (Stockholm)

17.00 Roger Tsien Breeding and building molecules to spy on cells and tumors – I142

Department of Chemistry and Biochemistry, University of California San Diego

18.00 Hall H, Foyer Opening Mixer

Sunday, June 27, 2010

08.30–11.00 Congress Hall A – Molecules in Health and Disease. A1 – Ageing

Chairperson: Marija Cvijovic (Göteborg)

08.30 Thomas Nyström Unequal inheritance of protein damage during yeast cytokinesis – I89

Department of Cell and Molecular Biology, University of Gothenburg, Göteborg, Sweden

09.00 Nils-Göran Larsson Regulation of mtDNA expression in disease and ageing – I70

Max Planck Institute for Biology of Ageing, Köln, Germany

09.30 Gro Amdam Dual insulin signaling in fat tissue linking food choice and aging in honey bees – I02

University of Life Sciences, As, Norway and School of Life Sciences, Arizona State University, Tempe, Arizona, USA

10.00 Tom Kirkwood Systems biology of ageing and longevity – I63 Ageing Research Laboratories, Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, UK

10.30 Cynthia McMurray Mechanisms of Age-related instability in the brain: the role of oxidation – I79

Lawrence Berkeley Laboratory, Berkeley, California, USA

08.30–11.00 Hall G3 B – Molecular Networks. B1 – Metabolic networks

Chairperson: Martin Lidell (Göteborg)

08.30 Uwe Sauer Transcriptional control of metabolic fluxes and compu-tational identification of the governing principles – I117

Institute of Molecular Systems Biology, ETH Zürich, Zürich, Switzerland

09.00 Bernhard Palsson The meta-structure of the E. coli genome and its genome-scale transcriptional regulatory network – I95

Department of Bioengineering, University of California San Diego, La Jolla, California, USA

09.30 Jens Nielsen Metabolism of filamentous fungi at the genome level – I86

Department of Chemical and Biological Engineering – Systems Biology, Chalmers University of Technology, Göteborg, Sweden

10.00 Matej Oresic Reconstruction and multi-scale modeling of lipid networks – I91

VTT Technical Research Centre of Finland, Espoo, Finland

10.30 Fredrik Bäckhed Global transcriptional regulation of the gut microbiota and its impact on host physiology – I06

Wallenberg Laboratory, University of Gothenburg, Göteborg, Sweden

08.30–11.00 Hall G4 C – Molecules at Work. C1 – Molecular Machines

Chairperson: Erik Boye (Oslo)

08.30 Mikael O´Donnell The E. coli replisome and use of clamps to bypass repli-cation barriers – I90

Laboratory of DNA Replication, The Rockefeller University, New York, USA

09.00 Dale Wigley How do helicases know which way to walk? – I155 Lincoln's Inn Fields and Clare Hall Laboratories, London Reseach Institute, Cancer Research London, UK

09.30 Elmar Schiebel Separation of centrosomes during the cell cycle – I120 Zentrum für Molekulare Biologie der Universität Heidelberg (ZMBH), Heidelberg, Germany

10.00 Måns Ehrenberg Lessons from the pH-sensitivity of the rate of peptidyl transfer from P-site to A-site tRNA on the translating ribosome – I32

Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden

10.30 Yossi Yarden Feedback control of receptor tyrosine kinases: Multiple defects in cancer – I157

Department of Biological Regulation, the Weizmann Institute of Science, Rehovot, Israel


08.30–11.00 Hall G2 D – Cellular Compartments. D1 – Secretory pathways

Chairperson: Per Sunnerhagen (Göteborg)

08.30 Gunnar von Heijne The ‘molecular code’ for membrane protein insertion into the ER – I150

Department of Biochemistry and Biophysics, The Arrhenius Laboratories for Natural Sciences, Stockholm University, Stockholm, Sweden

09.00 Graham Warren Golgi biogenesis in a protozoan parasite – I154 Max F. Perutz Laboratories, University of Vienna, Vienna, Austria

09.30 Anne Spang Identification of the switch in early-to-late endosome transition – I132

Biozentrum, University of Basel, Basel, Switzerland

10.00 Peter Novick Phosphatidylinositol 4-phosphate controls both mem-brane recruitment and a regulatory switch of the Rab GEF, Sec2p – I88

Department of Cell Biology, Yale University School of Medicine, New Haven, USA

10.30 Ida van der Klei Peroxisome inheritance in yeast: the involvement of multifunctional proteins – I145

Molecular Cell Biology, University of Groningen, Kluyver Centre for Genomics of Industrial Fermentation, Haren, The Netherlands

08.30–11.00 Hall J1 E – Biomolecular Design and Function. E1 – Synthetic Biology

Chairperson: Marcus Krantz (Göteborg)

08.30 Owe Orwar Controlling the rates of biochemical reactions and signaling networks by shape-and-volume changes – I92

Department of Chemical and Biological Engineering, Chalmers University of Technology, Göteborg, Sweden

09.00 Ülo Langel Applications of cell-penetrating peptides in oligonucle-otide delivery – I68

Department of Neurochemistry, Stockholm University, Stockholm, Sweden

09.30 Joerg Stelling Computational engineering of synthetic genetic circuits – I135

Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland

10.00 Sven Panke From understanding to designing enzymatic networks – I96

Institute of Process Engineering, ETH Zürich, Zürich, Switzerland

10.30 Ralf Wagner Synthetic Biology: Genes, genomes, applications – I151 Institute of Medical Microbiology and Hygiene, University of Regensburg, Regensburg, Germany

11.00–11.30 Coffee Break

11.30–12.30 Congress Hall EMBO Lecture

Chairperson: Israel Pecht (Rehovot)

11.30 Uri Alon Design principles of biological circuits – I01 Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel

12.30–13.00 Hall H Lunch service

13.00–15.30 Hall H Poster exhibition (Topics; B2, C2, C4, D2, E2)

13.00–15.30 Poster discussions

13.00 G2 Chair: Marija Cvijovic A1 Ageing: A1.04, A1.06, A1.07, A1.09, A1.10, A1.12, A1.15, A1.18, A1.19, A1.24, YSF-51

13.00 G3 Chair: Martin Lidell B1 Metabolic networks: B1.01, B1.09, B1.11, B1.17, B1.18, B1.19, B1.20, B1.24, B1.25, B1.26, B1.28, B1.33

13.00 G4 Chair: Jan Rydström C1,C5 Molecular machines and energy transduction: C1.01, C1.06, C1.07, C1.18, C1.20, C5.01, C5.04, YSF-05, YSF-42,YSF-75, YSF-77, YSF-116

14.15 G2 Chair: Per Sunnerhagen D1,D3-D5 Cellular Compartments: C4.33, D1.01, D1.02, D1.09, D3.04, D3.06, D5.03, D5.07, YSF-04, YSF-13,YSF-14, YSF-80, YSF-103

14.15 G3 Chair: Marcus Krantz E1 Synthetic biology: E1.01, E1.02, E1.06, E1.08, E1.11, E1.19, E1.20, E1.24, E1.29, YSF-74, YSF-89

14.15 G4 Chair: Jens Lagerstedt A2 Molecular immunology: A2.05, A2.06, A2.12, A2.16, A2.17, A2.21, A2.34, A2.39, A2.42, A2.45, A2.50, YSF-21


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13.00–15.30 C-Balkongen Speakers corner

13.00 Thomas Nyström, Uwe Sauer, Mikael O’Donnell, Gunnar von Heijne, Owe Orwar, Uri Alon

13.30 Nils-Göran Larsson, Bernhard Palsson, Dale Wigley, Graham Warren, Ülo Langel

14.00 Gro Amdam, Jens Nielsen, Elmar Schiebel, Anne Spang, Joerg Stelling

14.30 Tom Kirkwood, Matej Oresic, Måns Ehrenberg, Peter Novick, Sven Panke

15.00 Cynthia McMurray, Fredrik Bäckhed, Yossi Yarden, Ida van der Klei, Ralf Wagner

13.00–15.30 Hall J1 Biofuels are more than fuels – by the FEBS Science and Society Committee

Chairperson: Giorgio Semenza (Zürich)

13.00 Bärbel Friedrich Nature’s way to exploit dihydrogen as an alternative fuel – I39

Institute of Biology/Microbiology, Humboldt University, Berlin, Germany

13.45 Fraser Armstrong A chemist’s view of the challenges for biohydrogen – I04

Department of Chemistry, University of Oxford, Oxford, UK

14.30 Uri Pick Accumulation of triglycerides in green algae:? a poten-tial for biodiesel – I100

Department of Biological Chemistry, Weizmann Institute of Sciences, Rehovot, Israel

14.50 Samuel C. Zeeman Understanding starch? biosynthesis in plants: the potential to improve raw materials for biofuel ?production – I159

Institute of Plant Sciences, ETH Zürich, Zürich, Switzerland

15.10 Marc van Montagu A brief discussion on EtOH production – I146 Institute of Plant Biotechnology for Developing Countries, University of Ghent, Ghent, Belgium

15.30–17.00 Hall G2 Technology Workshop – Protein Expression

Chairpersons: Karin Lindkvist (Göteborg) and Sophia Hober (Stockholm)

15.30 Sophia Hober Progress in production and purification of proteins – I56 Department of Proteomics, Royal Institute of Technology, Stockholm, Sweden

16.15 Dikatein Rivka TISU, a common transcription and translation element specific to mRNAs with extremely short 5’UTR – B4.51

Weizmann Institute of Science, Rehovot, Israel

16.30 David Vikström Overexpressing ‘difficult proteins’ in Escherichia coli – B5.67

CBR-Center for Biomembrane Research, Stockholm University, Stockholm, Sweden

16.45 Annie Barrand-Frelet Lactococcus lactis, an alternative system for functional expression of peripheral and intrinsic plant membrane proteins – C4.07

Laboratoire de Physiologie Cellulaire Vegetale, CNRS, UJF, INRA, CEA, iRTSV, Grenoble, CEA Saclay/iBiTec-S/SB2SM/LSOD, Gif sur Yvette, France

15.30–17.00 Hall G3 Technology Workshop – Life cell imaging

Chairpersons: Mattias Goksör (Göteborg) and Thomas Huser (Davis)

15.30 Thomas Huser Imaging HIV transfer between T cells with optical superresolution – I59

NSF Center for Biophotonics Science and Technology, University of California, Davis, Sacramento, USA

16.00 Johan Elf Probing intracellular kinetics at the level of single molecules – I34

Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden

16.30 Elin Esbjörner Multiparametric fluorescence microscopy imaging of amyloid beta allows for direct observations of protein misfolding in vitro and in cells – A4.39

University of Cambridge, Chemistry, Cambridge, UK

16.45 Pyotr Tyurin-Kuzmin Hydrogen peroxide generated during the RTKs signaling produces and acts locally confined – B2.98

Moscow State University, Faculty of Basic Medicine, Moscow, Russian Federation

15.30–17.00 Hall G4 Technology Workshop – Bioinformatics

Chairpersons: Tore Samuelsson (Göteborg) and Alex Bateman (Hinxton)

15.30 Alex Bateman The billion protein question – I09 Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK

16.15 Olga Kalinina Predicting novel protein-small molecule interactions via a network of 3D structures – E2.18

University of Heidelberg, Exzellenzcluster CellNetworks, Heidelberg, Germany

16.30 Massimo Sandal The tube model in Gromacs: A platform for the study of protein folding and aggregation – E4.18

University of Cambridge, Department of Chemistry, Cambridge, UK

16.45 Laura Guasch Three-dimensional quantitative structure-activity rela-tionships (3D-QSAR) study of PPAR? partial agonists – A3.37

17.15–18.15 Congress Hall Nobel Laureate Lecture

Chairperson: Jan Rydström (Göteborg)

John Walker The mechanism and regulation of F-ATPases – I153 MRC Mitochondrial Biology Unit, Cambridge, UK


18.15–19.15 Congress Hall Bücher Lecture

Chairperson: Ulrich Brandt (Frankfurt am Main)

Svante Pääbo Analyses of pleistocene genomes – I94 Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany

19.30–23.00 Blomstermåla, Särö

FEBS Dinner

Chairpersons: Israel Pecht (Rehovot) and Emmanuel Fragoulis (Athens)

On invitation only

Monday, June 28, 2010

08.30–11.00 Congress Hall A – Molecules in Health and Disease. A2 – Molecular Immunology

Chairpersons: Gunnar Hansson (Göteborg)

08.30 Anna M Blom Relationships between structure and functions of a major complement inhibitor C4b-binding protein – I14

Department of Laboratory Medicine, Lund University, University Hospital, Malmö,Sweden

09.00 Inga-lill Mårtensson The pre-B cell receptor checkpoint – I77 Developmental Immunology, The Babraham Institute, Cambridge, UK and Department of Rheumatology and Inflammation Research, University of Gothenburg, Göteborg, Sweden

09.30 Matthias Merkenschlager Disentangling canonical cohesin functions in chromo-some maintenance from non-canonical functions in gene regulation and genome organisation – I80

MRC Clinical Sciences Centre, Imperial College London, London, UK

10.00 Maria Rescigno EMBO Young Investigator Lecture: TLR4 mediated skin carcinogenesis is dependent on immune and radioresistant cells – I111

Department of Experimental Oncology, European Institute of Oncology, Milan, Italy

10.30 Pärt Peterson Autoimmune Regulator: molecular mechanisms of central immune tolerance – I98

Department of Molecular Pathology, Institute of General and Molecular Pathology, Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia

08.30–11.00 Hall G3 B – Molecular Networks. B2 – Signal Transduction


08.30 Jen Sheen Differential innate immune signalling via Ca2+ sensor protein kinases in plants – I127

Department of Molecular Biology, Massachusetts General Hospital and Department of Genetics, Harvard Medical School, Boston, USA

09.00 Kjetil Taskén Spatiotemporal control of cyclic AMP signaling processes – I139

The Biotechnology Centre of Oslo and Centre for Molecular Medicine Norway, Nordic EMBL Partnership, University of Oslo, Blindern, Norway

09.30 John D Scott Cell Signaling in Space and Time – I125 Department of Pharmacology, University of Washington School of Medicine, Seattle, USA

10.00 Ivan Dikic Ubiquitin-mediated regulation of NF-KappaB activation and autophagy – I29

Institute of Biochemistry II and Cluster of Excellence Frankfurt, Goethe University School of Medicine, Frankfurt (Main), Germany

10.30 Phil Cohen The interplay between phosphorylation and ubiquiti-nation in regulating the innate immune system – I23

MRC Protein Phosphorylation Unit, University of Dundee, Dundee, UK

08.30–11.00 Hall G4 C – Molecules at Work. C2 – Biological Cycles

Chairperson: Matteo Barberis (Berlin)

08.30 Michael Brunner Molecular mechanism of photo-adaptation and light entrainment of the circadian clock of Neurospora crassa – I20

Biochemistry Center, Heidelberg University, Heidelberg, Germany

09.00 Paloma Mas EMBO Young Investigator Lecture: A functional role for protein kinase CK2 in the Arabidopsis circadian sys-tem – I78

Centre for Research in Agricultural Genomics (CRAG); Consortium CSIC-IRTA-UAB , Barcelona, Spain

09.30 Hiroki Ueda Systems biology of mammalian circadian clocks – I143 Laboratory of Biomolecular Informatics, RIKEN Center, Kobe, Japan

10.00 Aziz Sancar Circadian clock control of the cellular response to DNA damage – I115

Department of Biochemistry and Biophysics, UNC School of Medicine, Chapel Hill, USA

10.30 Arp Schnittger EMBO Young Investigator Lecture: Cell cycle control during growth and reproduction – I121

Institut de Biologie Moléculaire des Plantes du CNRS, IBMP-CNRS – UPR2357, Université de Strasbourg, France.


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08.30–11.00 Hall G2 D – Cellular Compartments. D2 – Mitochondria

Chairperson: Elzbieta Glaser (Stockholm)

08.30 Nikolaus Pfanner The mitochondrial machinery for import and assembly of proteins – I99

Institute of Biochemistry and Molecular Biology, ZBMZ, University of Freiburg, Freiburg, Germany

09.00 Johannes Herrmann What mitochondria learned from their bacterial ancestors: Oxidation-driven protein folding – I54

Department of Cell Biology, University of Kaiserslautern, Kaiserslautern, Germany

09.30 Paulo Bernardi Pathophysiology of the mitochondrial permeability transition – I12

Department of Biomedical Sciences, University of Padova, and Consiglio Nazionale delle Ricerche Center, Padova, Italy for the Study of Biomembranes, Padova, Italy

10.00 Maria Falkenberg Mechanisms of initiation of DNA replication in human mitochondria – I37

Department of Medical Biochemistry and Cell Biology, University of Gothenburg, P.O. Box 440, SE-405 30 Gothenburg, Sweden

10.30 Luca Scorrano EMBO Young Investigator Lecture: Size matters: mitochondria elongate to support survival of starving cells – I124

Venetian Institute of Molecular Medicine, Padova, Italy

08.30–11.00 Hall J1 E – Biomolecular Design and Function. E2 – Molecular Recognition

Chairperson: Richard Neutze (Göteborg)

08.30 Ute Krengel Hypothesis: Molecular basis of cholera blood group dependence and implications for a world characterized by climate change – I66

Department of Chemistry, University of Oslo, Oslo, Norway

09.00 Attila Remenyi Protein-protein interactions in MAP kinase mediated signaling networks – I110

Department of Biochemistry, Eotvos Lorand University, Budapest, Hungary

09.30 Gebhard Schertler Structure of Active and Inactive G Protein Coupled Receptors: Implications for Signaling and PharmacologyStructure of Active and Inactive G Protein Coupled Receptors: Implications for Signaling and Pharmacology – I119

MRC Laboratory of Molecular Biology, Cambridge, UK

10.00 Irmi Sinning SIMIBI class NTP binding proteins in co- and posttrans-lational targeting – I129

Biochemistry Center, Heidelberg University, Heidelberg, Germany

10.30 Karin Dahlman-Wright Molecular characterization of estrogen receptor signaling in breast cancer cells – I26

Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden


11.30–12.30 Congress Hall IUBMB Lecture

Chairperson: Stathis Gonos (Athens)

11.30 Susan Lindquist Protein folding and inheritance of environmentally acquired characteristics – I73

Whitehead Institute for Biomedical Research, MIT, Cambridge MA


13.00–15.30 Hall H Poster exhibition (Topics; A3, A4, B3, B4, C3, E3)


13.00 G3 Chair: Bengt Persson C2,C4 Membrane transport Biological cycles: B2.51, B2.88, C4.13, C4.23, C4.27, C4.28, C4.34, YSF-62, YSF-79, YSF-83, YSF-86, YSF-122

13.00 G4 Chair: Stefan Hohmann B2 Signal transduction: B2.04, B2.05, B2.25, B2.30, B2.41, B2.46, B2.55, B2.71, B2.89, B2.93, B2.99, B2.111

14.15 G3 Chair: Richard Neutze E2 Molecular recognition: B2.96, E2.01, E2.03, E2.04, E2.06, E2.11, E2.12, E2.14, E2.16, E2.19, E2.20, E2.25

14.15 G4 Chair: Elzbieta Glaser D2 Mitochondria: D2.01, D2.07, D2.08, D2.12, D2.18, D2.21, D2.22, D2.24, YSF-22, YSF-39, YSF-71, YSF-125


13.00 Anna M Blom, Jen Sheen, Michael Brunner, Nikolaus Pfanner, Ute Krengel, Susan Lindquist

13.30 Inga-lill Mårtensson, Kjetil Taskén, Paloma Mas, Johannes Herrmann, Attila Remenyi

14.00 Matthias Merkenschlager, John D Scott, Hiroki Ueda, Paulo Bernardi, Gebhard Schertler

14.30 Maria Rescigno, Ivan Dikic, Aziz Sancar, Maria Falkenberg, Irmi Sinning

15.00 Pärt Peterson, Phil Cohen, Arp Schnittger, Luca Scorrano, Karin Dahlman-Wright


13.00–15.30 Hall J1 The Researching, Teaching and Learning Triangle at Universities: Unite or Divide? – by the FEBS Education Committee

Chairpersons: Miguel Castanho (Lisbon) and Gül Güner-Akdogan (Izmir)

13.00 Miguel Castanho Context, motivation and timeliness of the theme Department of Biophysics, School of Medicine, Lisbon, Portugal

13.10 Ana Sebastião Research in undergraduate medical education – I126 Institute of Neurosciences and Pharmacology, School of Medicine, Lisbon, Portugal

13.30 Jane Saffell Research in the early stages of scientific curricula – I113 Department of Life Sciences, Imperial College, London, UK

13.50 Jorge Guimarães Nation-wide program for undergradute research: The long Brazilian experience

President of CAPES, Brazil

14.10 Susan Hamilton The Advanced Study program in science: Exposing motivated and interested students to the research culture of the University of Queensland – I164

President, Academic Board, University of Queensland, Brisbane, Australia

14.30 Moderator: Jason Perret Panel discussion with the speakers Laboratoire de Chimie Biologique et de la Nutrition, Faculté de Médecine, Université Libre de Bruxelles, Belgium,Laboratoire de Chimie Biologique et de la Nutrition (L.C.B.N.), Faculté de Médecine, Université Libre de Bruxelles, Belgium

13.30–15.00 Hall G2 Scientific Careers – by the FEBS Young Scientists Forum

Chairperson: Daniela Corda (Napoli)

Karl Kuchler The FEBS Programme – Opportunities for Training & Education of Young Scientists in Molecular Biosciences

Max F. Perutz Laboratories, Medical University Vienna, Vienna, Austria

Eeva Moilanen Career in Drug Research – Opportunities and Challenges Department of Pharmacology, University of Tampere, Tampere, Finland

Alan Craig “People” programme; Marie Curie actions European Commission, DG Education and Culture (EAC), Brussels, Belgium

Moderator: Daniela Corda General discussion National Research Council, Napoli, Italy

15.30–17.00 Hall G3 Technology Workshop – Proteomics Technologies

Chairpersons: Gunnar Hansson (Göteborg) and Paola Picotti (Zürich)

15.30 Chunaram Choudhary High resolution quantitative mass spectrometry for analysis of proteomes and PTMs – I22

Department of Proteomics, The NNF Center for Protein Research, University of Copenhagen, Denmark

16.00 Paola Picotti Quantitative targeted proteomics for the analysis of cellular networks – I101

Institute of Molecular Systems Biology, ETH Zürich, Zürich, Switzerland

16.30 Katarina Alenäs Heat inactivation of tissue samples to stabilize proteins, peptides and their modifications – A4.40

Denator AB, Göteborg, Sweden

16.45 Daniel Auerbach An integrated experimental workflow to increase throughput and data robustness for analysis of mam-malian protein interaction networks – B2.32

Dualsystems Biotech AG, Schlieren, Switzerland

15.30–17.00 Hall G2 Technology Workshop – Metabolomics

Chairpersons: Jens Nielsen (Göteborg) and Nicola Zamboni (Zürich)

15.30 Nicola Zamboni A pragmatic update on cellular metabolomics – I158 Institute of Molecular Systems Biology, ETH Zürich, Zürich, Switzerland

16.15 Erna Knutsdottir Comparison of lipid and fatty acids composition of basolateral membrane from rat (Rattus norvegicus) and Atlantic cod (Gadus morhua) intestinal enterocytes: The question of homeoviscous adaptation – C4.15

Science Institute, University of Iceland, Department of Biochemistry, Reykjavik, Iceland

16.30 Kuk-Ki Hong Metabolome analysis of yeast strains with improved galactose uptake


16.45 Pramote Chumnanpuen Dynamic footprinting for phenotypic profiling of yeast Department of Chemical and Biological Engineering – Systems Biology, Chalmers University of Technology, Göteborg, Sweden

15.30–17.00 Hall G4 Technology Workshop – Dynamic Modelling

Chairpersons: Marija Cvijovic (Göteborg) and Ursula Kummer (Heidelberg)

15.30 Ursula Kummer Assessing the importance of individual players in biochemical networks in a global way – I67

Bioinformatics and Computational Biochemistry Group, EML Research, Heidelberg, Germany

16.15 Matteo Barberis Sic1 plays a role in timing and oscillatory behaviour of B-type cyclins in yeast – B5.14

Theoretical Biophysics, Humboldt University Berlin, Berlin, Germany


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16.30 Elena Papaleo Identification of a molecular switch regulated by phos-phorylation in E2 ubiquitin-conjugating enzymes – B5.53

University of Milano-Bicocca, Milano, Italy

16.45 Ana Kitanovic Computer controlled automated assay for comprehen-sive studies of S.cerevisiae growth kinetic in response to extracellular conditions – C2.03

Institute for Pharmacy and Molecular Biotechnology, University of Heidelberg, Heidelberg, Germany

15.40–18.00 Hall J1 Research-Oriented Education at High Schools – by the FEBS Education Committee

Chairpersons: Jane Saffell (London) Gül Güner-Akdogan (Izmir)

15.40 Jane Saffell Introduction

15.50 Gül Güner-Akdogan Coordinating Research Project competitions between High School students in the Izmir region

16.00 Various speakers Short Presentations from the science teachers

16.20 Small group discussions

17.20 Various speakers Report to the whole group and whole group discussion

17.50 Jane Saffell and Gül Güner-Akdogan

Conclusions


Chairperson: Erik Boye (Oslo)

Elizabeth Blackburn Telomeres and telomerases – I13 Department of Biochemistry and Biophysics, University of California San Fransisco, San Fransisco, USA

18.15–18.45 Congress Hall Special event

Uri Alon (and his guitarr) Importance of Emotional and Subjective Sides of Science Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel

18.30–19.30 Hall J1 Annual proceedings of the Swedish Society for Biochemistry and Molecular Biology

Chairperson: Stefan Hohmann

Tuesday, June 29, 2010

08.30–11.00 Congress Hall A – Molecules in Health and Disease. A3 – Metabolic Diseases

Chairperson: Sven-Olof Olofsson (Göteborg)

08.30 Antonio Vidal-Puig An allostatic control of membrane lipid composition in obeisty by SREBP1 – I149

Institute of Metabolic Science-Metabolic Research Labora-tories and Department of Clinical Biochemistry, University of Cambridge, Cambridge, UK

09.00 Göran Hansson Immune regulation of lipid metabolism and atherosclerosis Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden.

09.30 Sven Enerbäck Human Brown Adipose Tissue – I35 Department of Biomedicine, University of Gothenburg, Göteborg, Sweden

10.00 Dominique Langin Metabolism and inflammation in human adipose tissue – I69

Inserm, Rangueil Institute of Molecular Medicine, Obesity Research Laboratory, Toulouse, France

10.30 Ulf Eriksson Vascular endothelial growth factor B controls endothelial fatty acid uptake

Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden

08.30–11.00 Hall G3 B – Molecular Networks. B3 – Global networks

Chairperson: Jens Nielsen (Göteborg)

08.30 Charlie Boone The genetic landscape of a cell – I17 Banting and Best Department of Medical Research, University of Toronto, Toronto, Canada

09.00 Marc Vidal Interactome networks and human disease – I148 Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA

09.30 Giulio Superti-Fuga Molecular networks in Leukemia and Innate immunity – I138

Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria

10.00 Ben Lehner Perturbing genes and predicting the outcome – I72 EMBL-CRG Systems Biology Unit, Centre for Genomic Regulation, UPF, Barcelona, Spain

10.30 Dirk Bumann Salmonella metabolism during infection – I10 Infection Biology, Biozentrum, University of Basel, Basel, Switzerland


08.30–11.00 Hall J1 C – Molecules at Work. C3 – Extracellular structures

Chairperson: Anna Blom (Lund)

08.30 Jean-Paul Latge Cell wall and extracellular matrix in the human opportunistic fungus Aspergillus fumigatus – I71

Pasteur Institute, Paris, France

0900 Taina Pihlajaniemi The homologous collagens XV and XVIII have distinct physiological roles – I102

Department of Medical Biochemistry and Molecular Biology, University of Oulu, Oulu, Finland

09.30 Johanna Ivaska EMBO Young Investigator Lecture: Regulation of epithelial cell migration, invasion and EMT – I60

Turku Centre for Biotechnology, Turku, Findland

10.00 Nikos Karamanos Implication of extracellular matrix in growth and meta-static potential of human breast cancer cells to bone: the role of zoledronate – I62

Department of Chemistry, University of Patras, Greece

10.30 Liliana Schaefer Biglycan signaling: Toll-like receptors, the NLRP3- inflammasome and beyond – I118

Institut für Allgemeine Pharmakologie und Toxikologie, Universitätsklinikum, Frankfurt, Germany

08.30–11.00 Hall G2 D – Cellular Compartments. D3 – Endocytosis

Chairperson: Jens Lagerstedt (Lund)

08.30 Peter Deen Exocytosis, endocytosis and lysosomal targeting of the Aquaporin-2 water channel: an interplay of phosphoryla-tion and ubiquitination – I28

Department of Physiology, Radboud University of Nijmegen Medical Center, Nijmegen, Netherlands

09.00 David J Owen Cargo recognition by the AP2 endocytic adaptor complex – I93

Cambridge Institute for Medical Research, Department of Clinical Biochemistry, University of Cambridge, Cambridge, UK

09.30 Kirsten Sandvig Protein toxins from plants and bacteria: Probes for intra-cellular transport and tools in medicine – I116

Centre for Cancer Biomedicine, Faculty Division Norwegian Radium Hospital, University of Oslo, Oslo, Norway

10.00 Giorgio Scita The endocytic networks in the control of the plasticity of tumor cell migration – I123

Department of Medicine, Surgery and Dentistry of the University of Milan, Milan, Italy

10.30 Anna Elisabetta Salcini PI3KC2alpha, a class II PI3K, is required for dynamin-independent internalization pathways – I114

Biotech Research and Innovation Centre, University of Copenhagen, Copenhagen, Denmark

08.30–11.00 Hall G4 E – Biomolecular Design and Function. E3 – Design of Macromolecules

Chairperson: Karin Lindkvist (Göteborg)

08.30 Birte Höcker Protein design from fold fragments – I57 Max Planck Institute for Developmental Biology, Tübingen, Germany

09.00 Stefan Ståhl Affibody molecules: Engineered proteins for therapeutic, diagnostic and biotechnological applications – I134

Division of Molecular Biotechnology, Royal Institute of Technology, Stockholm, Sweden

09.30 Edvard Bayer Designer cellulosomes: Synthetic multi-enzyme macro-molecular complexes – I11

Department of Biological Chemistry, The Weizmann Institute of Science, Rehovot, Israel

10.00 Christina Smolke Engineering RNA controllers for programming cellular behavior – I131

Department of Bioengineering, Stanford University, Stanford, USA

10.30 Tanja Kortemme Molecular Design – from proteins to networks, coupling computation and experiment – I65

California Institute for Quantitative Biosciences, University of California San Francisco, San Francisco, USA


11.30–12.30 Congress Hall Krebs Medal Lecture

Chairperson: Giorgio Semenza (Zürich)

11.30 Harald Stenmark How a lipid mediates tumour suppression – I136 Centre for Cancer Biomedicine, University of Oslo and Department of Biochemistry, Institute for Cancer Research, the Norwegian Radium Hospital, Montebello, Norway


13.00–15.30 Hall H Poster exhibition (Topics; A5, B5, E4, E5, YSF)


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13.00 G2 Chair: Sven-Olof Olofsson

A3 Metabolic diseases: A3.11, A3.22, A3.32, A3.63, A3.69, A3.71, A3.73, A3.81, B1.36, B4.71, B4.72

13.00 G3 Chair: Jens Nielsen B3 Global networks: A5.63, B2.32, B2.85, B2.86, B3.02, B3.03, B3.05, B3.07, B3.12, B3.13, YSF-20

13.00 G4 Chair: Gunnar Hansson C3 Extracellualr structures: C1.23, C3.03, C3.04, C3.05, C3.09, C3.13, C3.15, C3.17, C3.23, C3.25, YSF-43, YSF-76

14.15 G2 Chair: Karin Lindkvist E3 Design of macromolecules: E3.09, E3.11, E3.12, E3.14, E3.16, E3.18, E3.19, YSF-44, YSF-60, YSF-68, YSF-81, YSF-117

14.15 G3 Chair: Andrew Ewing A4 Neurobiology: A4.12, A4.13, A4.20, A4.24, A4.25, A4.26, A4.29, A4.36, A4.37, A4.39, A4.41, A4.48

14.15 G4 Chair: Claes Gustafsson B4 Gene regulation: B4.07, B4.19, B4.24, B4.32, B4.44, B4.49, B4.51, B4.54, B4.66, B4.69, D4.07, YSF-121


13.00 Antonio Vidal-Puig, Charlie Boone, Jean-Paul Latge, Peter Deen, Birte Höcker, Harald Stenmark

13.30 Göran Hansson, Marc Vidal, Taina Pihlajaniemi , David J Owen, Stefan Ståhl

14.00 Sven Enerbäck, Giulio Superti-Fuga, Johanna Ivaska, Kirsten Sandvig, Edvard Bayer

14.30 Dominique Langin, Ben Lehner, Nikos Karamanos, Giorgio Scita, Christina Smolke

15.00 Ulf Eriksson, Dirk Bumann, Liliana Schaefer, Anna Elisabetta Salcini, Tanja Kortemme

13.00–15.30 Hall J1 Tutorial: Practical Systems Biology – by the FEBS Education Committee

Chairpersons: Marcus Krantz (Göteborg) and Gül Güner-Akdogan (Izmir)

13.00–15.30 Congress Hall East-NMR Workshop: NMR in Biology – In Interaction

Chairpersons: Lucia Bianci (Florence) and Göran Karlsson (Göteborg)

13.00 Lucia Bianci The East NMR and the BioNMR initiatives Centro Risonanze Magnetiche, University of Florence, Florence, Italy

13.45 Volker Dötsch Cell free protein expression and membrane protein structure determination by NMR

Institute of Biophysical Chemistry, University of Frankfurt, Frankfurt, Germany

14.30 Jacob Anglister TBA Department of Structural Biology, Weizmann Institute of Science, Rehovot, Israel

15.00 Göran Karlsson Transient protein interaction and NMR Swedish NMR Centre, University of Gothenburg, Göteborg Sweden

15.30–17.00 Hall G3 Technology Workshop – Protein Interaction

Chairpersons: Anders Blomberg (Göteborg) and Igor Stagljar (Toronto)

15.30 Igor Stagljar Protein Networks Regulating Cell Signaling in Human Health and Disease – I133

Terrence Donnelly Centre for Cellular and Biomolecular Research, Department of Biochemistry and Department of Molecular Genetics, University of Toronto, Canada

16.00 Matthias Gstaiger Systematic analysis of dynamic signaling modules by quantitative mass spectrometry – I47

Institute for Molecular Systems Biology, ETH, Zürich, Switzerland

16.30 Jochen Schwenk GABAB receptors are heteromultimers with a family of auxiliary subunits – A4.37

Institute of Physiology II, University of Freiburg, Freiburg, Germany

16.45 Sandra Orchard The PSICQUIC interface — a portal into to the world of the interactome – B3.07

Proteomics Services Team, EMBL-EBI, Cambridge, UK

15.30–17.00 Hall G2 Technology Workshop – Lipidomics

Chairpersons: Sven-Olof Olofsson (Göteborg) and Kim Ekroos ( Espoo)

15.30 Kim Ekroos Lipidomics in health and disease – I33 ZORA Biosciences, Espoo, Finland

16.00 Ole Kristian Greiner- Tollersrud

Characterisation of two new enzymes involved in lyso-somal phospholipid degradation – B1.11

Institute of Medical Biology, University of Tromsø, Tromsø, Norway

16.30 Massimo Aureli Plasma membrane associated enzymes for sphingolipid structural changes and neuronal development – B1.07

Department of Medical Chemistry, University of Milan, Milan, Italy

16.45 Cristina Cianflone Diacylglycerol kinase alpha regulates SDF1?-induced cell invasion by regulating atypical PKC and matrix metallo proteinases 9 – B2.17

Department of Clinical and Experimental Medicine, University of Piemonte Orientale Amedeo Avogadro, Novara, Italy


15.30–17.00 Hall G4 Technology Workshop – Applying Sequencing Technologies

Chairpersons: Per Elias (Göteborg) and Joakim Lundeberg (Stockholm)

15.30 Joakim Lundeberg Intense parallel sequencing and high sensitivity identifi-cation of mutations, transcriptomes and genomes – I75

Department of Biotechnology, Royal Institute of Technology, Stockholm, Sweden

16.00 Thomas Svensson Strategies to handle massive DNA sequencing data Science for Life Laboratory, KI Science Park, Stockholm, Sweden

16.25 Erik Kristiansson Antibiotic-contaminated effluent promotes mobile resistance in environmental bacteria – A5.62

Department of Neuroscience and Physiology, University of Gothenbur, Göteborg, Sweden

16.35 Dalanya Mohammed Comparative analysis of the Tn1546 element from newly isolated and identified vancomycin resistant staphylococcus aureus strain – A5.24

College of Science, Biology, University of Sulaimani, Sulaimani-Kurdistan, Iraq

16.45 Wanwipa Vongsangnak Genome sequencing, annotation and analysis of Saccharomyces cerevisiae: from genotype to phenotype for industrial biotechnology applications – B1.28


17.15–18.15 Congress Hall FEBS Journal Prize and FEBS Letters Award Lectures

Chairpersons: Felix Wieland (Heidelberg) and Richard Perham (Cambridge UK)

Mercedes Munkonda FEBS Journal Prize: A monoclonal antibody as the first specific inhibitor of human NTPDase3

Institute of Cardiology and Pneumology, Laval University, Québec, Canada

Hideo Iwai FEBS Letters Award: Structural basis for the design of a new split intein suitable for site-specific chemical modification

Institute of Biotechnology, University of Helsinki, Finland

18.15–18.45 Congress Hall Svedberg Lecture 2010


Per Jemth Allosteric pathways in protein domains: sequence versus topology – I166

Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden

19.30–23.00 Trädgårds-föreningen

Social Dinner – Midsummer party

Wednesday, June 30, 2010

08.30–11.00 Hall G3 A – Molecules in Health and Disease. A4 – Neurobiology

Chairperson: Winnie Eskild (Oslo)

08.30 Andrew Ewing Quantitative electrochemical cytometry of nanometer transmitter vesicles – what fraction is released in exocytosis? – I165

Department of Chemistry, University of Gothenburg, Göteborg, Sweden

09.00 Chris Dobson Life on the Edge: The Generic Nature of Protein Misfolding Disorders – I30

Department of Chemistry, University of Cambridge, Cambridge, UK

09.30 Tõnis Timmusk Molecular dissection of the calcium-regulated tran-scriptional activator TCF4/ITF2/E2-2 in neurons – I140

Department of Gene Technology, Tallinn University of Technology, Tallinn, Estonia

10.00 Mahmood Amiry-Moghaddan

Aquaporin water channels in health and disease – I03 Center for Molecular Biology and Neuroscience and Department of Anatomy, University of Oslo, Oslo, Norway

10.30 Laurent Groc High-resolution imaging of neurotransmitter receptors: learning from a single molecule – I44

CNRS-UMR 5091 Physiologie Cellulaire de la Synapse, Institut François Magendie, Université Bordeaux, Bordeaux, France

08.30–11.00 Congress Hall B – Molecular Networks. B4 – Gene regulation

Chairperson: Claes Gustafsson (Göteborg)

08.30 Francesc Posas Control of gene expression by the Hog1 stress-activated protein kinase – I105

Departament of Experimental Health Sciences, Universitat Pompeu Fabra, Parc de Recerca Biomèdica de Barcelona (PRBB), Barcelona, Spain, Departament de Ciències Experi-mentals i de la Salut, Universitat Pompeu Fabra, Parc de Recerca Biomèdica de Barcelona

09.00 Henk G Stunnenberg The transcriptional and epigenetic targets of the AML associated oncofusion proteins AML1-ETO and PML-RAR<alpha> – I137

Department of Molecular Biology, Radboud University Nijmegen, Nijmegen, Netherlands

09.30 Richard Treisman MAL: linking the actin cytoskeleton to transcriptional regulation – I141

Lincoln's Inn Fields and Clare Hall Laboratories, London Research Institute, Cancer Research, London, UK


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10.00 Albertha J Walhout Gene-centered regulatory networks – I152 University of Massachusetts Medical School, Worcester, USA

10.30 Kevin Verstrepen Unstable tandem repeats in promoters confer transcrip-tional evolvability – I147

VIB Laboratory of Systems Biology, Katholieke Universiteit Leuven, Leuven, Belgium

08.30–11.00 Hall G4 C – Molecules at Work. C4 – Transmembrane transport

Chairperson: Bengt Persson (Kalmar)

08.30 Poul Nissen A revised model of the mechanism of P-type ATPase cation pumps – I87

Centre for Structural Biology, Department of Molecular Biology, University of Aarhus, Aarhus, Denmark

09.00 Carola Hunte Towards structural und functional characterization of human sodium/proton antiporters

Institute of Membrane and Systems Biology, University of Leeds, Leeds, UK

09.30 Richard Neutze Structural insights into eukaryotic aquaporin regulation – I84

Department of Chemistry, University of Gothenburg, Göteborg, Sweden

10.00 Bert Poolman Substrate-binding proteins: A structural classification and the mechanism of peptide selection by the transport receptor OppA – I104

Groningen Biomolecular Sciences and Biotechnology Institute and Zernike Institute for Advanced Materials, Riksuniversiteit Groningen, Groningen, The NetherlandsUniversity of Groningen, Nijenborgh, Netherlands.

10.30 Raimond Dutzler The Structural basis for ion conduction and gating in pentameric ligand-gated ion channels – I31

Biochemisches Institut, Universität Zürich, Zürich, Switzerland

08.30–11.00 Hall G2 D – Cellular Compartments. D4 – Nucleus

Chairperson: Camilla Sjögren (Stockholm)

08.30 Helle Ullrich Timing and spacing of ubiquitin-dependent DNA damage bypass – I144

Cancer Research UK London Research Institute, Clare Hall Laboratories, South Mimms, UK

09.00 Claudia Lukas Real-time microscopy and high-content imaging as essential tools to dissect dynamics of the DNA damage response – I74

Center for Genotoxic, Danish Cancer Society, Copenha-gen, Denmark

09.30 Dirk Görlich Transport through nuclear pore complexes – I42 Max Planck Institute for Biophysical Chemistry, Göttingen, Germany

10.00 Francois Fuks EMBO Young Investigator Lecture: Mechanisms of DNA methylation in mammals – I40

Laboratory of Molecular Virology, Free University of Brussels, Brussels, Belgium

10.30 Camilla Sjögren The SMC5/6 complex and replication-induced topological stress – I130

Department of Cell and Molecular Biology, Karolinska Institute, Stockholm, Sweden

08.30–11.00 Hall J1 E – Biomolecular Design and Function. E4 – Folding

Chairperson: Per Elias (Göteborg)

08.30 Sheena Radford How well evolved is the folding code? – I106 Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, UK

09.00 Lucia Banci Folding and redox processes in the mitochondria – I07 Magnetic Resonance Center and Department of Chemistry, FiorGen Foundation, University of Florence, Sesto Fiorenti-no, Italy

09.30 Annalisa Pastore Frataxin, not any longer a function orphan protein – I97 The National Institute for Medical Research, The Ridgeway, Mill Hill, London, UK

10.00 Christian Griesinger Folding and its redirection studied with NMR – I43 Max-Planck Institute for Biophysical Chemistry, Göttingen, Germany

10.30 Per Hammarström Svedberg Lecture 2009: The dynamic amyloid landscape – I49

IFM-Department of Chemistry, Linköping University, Linköping, Sweden


11.30–12.30 Congress Hall Datta Medal Lecture

Chairperson: Iain Mowbray (London)

11.30 Juleen Zierath Gene/Environment influence on skeletal muscle insulin sensitivity in Type 2 Diabetic patients – I160

Karolinska Institutet, Clinical Integrative Physiology, Stockholm, Sweden


13.00–15.30 Hall H Poster exhibition (Topics; A1, A2, B1, C1, C5, D1, D3, D4, D5, E1)


13.00–15.30 G3, G4 Poster discussions

13.00 G3 Chair: Hans Wolf-Watz A5 Infectious diseases: A5.07, A5.17, A5.55, A5.57, A5.58, A5.66, A5.67, A5.74, A5.76, A5.79, A5.80, YSF-18

13.00 G4 Chair: Per Elias E4 Folding: E4.03, E4.11, E4.13, E4.18, E4.22, E4.23, E4.24, E4.25, E4.26, E4.27, E4.29, E5.08

14.15 G3 Chair: Bengt Mannervik E5 Catalytic mechanisms: E5.05, E5.15, E5.17, E5.20, E5.23, E5.24, E5.25, E5.28, E5.34, E5.36, E5.42, E5.50

14.15 G4 Chair: Therese Jacobson B5 Regulation of protein function: B5.19, B5.28, B5.32, B5.47, B5.50, B5.53, B5.60, B5.62, B5.79, YSF-37, YSF-50, YSF-73


13.00 Andrew Ewing, Francesc Posas, Poul Nissen, Helle Ullrich, Sheena Radford, Juleen Zierath

13.00 Ralf Bartenschlager, Anne Simonsen, Ulrich Brandt, Egbert Boekema, Bengt Mannervik

13.30 Chris Dobson, Henk G Stunnenberg, Carola Hunte, Claudia Lukas, Lucia Banci

13.30 Wayne Hendrickson, Gerald W Hart, Shelagh Ferguson-Miller, Eva-Marie Aro, Donald Hilvert

14.00 Tõnis Timmusk, Richard Treisman, Richard Neutze, Dirk Görlich, Annalisa Pastore

14.00 Hans Wolf-Watz, Ivan Mijakovic, So Iwata, Holger Dau, Manfred Reetz

14.30 Mahmood Amiry-Moghaddan, Albertha J Walhout, Bert Poolman, Francois Fuks, Christian Griesinger

14.30 Pascale Cossart, Davide Corona, Wolfram Saenger, Chris Bowler, Maria Joao Ramos

15.00 Laurent Groc, Kevin Verstrepen, Raimond Dutzler, Camilla Sjögren, Per Hammarström

15.00 Shulamit Michaeli, Piet Gros, Peter Brzezinski, Ralph Bock, Isabelle Moura

13.00–14.30 Hall J1 Gender in Science – by the FEBS Working Group on Women in Science

Chairpersons: Ruth Paulssen (Tromsö)

13.00 Elizabeth Pollitzer Reaching consensus on the gender dimension in science Portia Ltd, London, UK

14.00 General discussion

13.00–15.30 Hall G2 Database Taster – organised by the European Bioinformatics Institute, EBI

13.00 Cath Brooksbank Brief introduction to the EMBL-EBI’s data resources Outreach and Training Team, EMBL-European Bioinformatics Institute, Hinxton, UK

13.15 Jennifer McDowall Proteomics resources (UniProt, InterPro) – I163 External Services Team, EMBL-European Bioinformatics Institute, Hinxton, UK

13.45 Adel Golovin Protein structures (PDBe) PDBe Team, EMBL-European Bioinformatics Institute, Hinxton, UK

14.15 Sandra Orchard Interactions and pathways: IntAct and Reactome Proteomics Services Team, EMBL-European Bioinformatics Institute, Hinxton, UK

14.45 Janna Hastings Small molecules (ChEBI and ChEMBLdb) – I162 Cheminformatics and Metabolomics Team, EMBL-European Bioinformatics Institute, Hinxton, UK

15.15 Open discussion

15.30–17.00 Hall G3 Technology Workshop – Protein Structures

Chairpersons: Richard Neutze (Göteborg) and Magnar Björås (Oslo)

15.30 Elspeth Garman From hot to cool and more for less: New developments for structural biology – I41

Department of Biochemistry, University of Oxford, Oxford, UK

16.15 Denys Pogoryelov On the rotary mechanism and ion binding specificity of F1Fo-ATP synthases – C5.01

Department of Structural Biology, Max Planck Institute of Biophysics, Frankfurt / M, Germany

16.30 Mark Currie Dissect and build: Reconstructing the cellulosome using X-ray crystallography and small angle X-ray scattering – C1.23

Biochemistry, Queen's University Kingston, Canada

16.45 Ilona Nudelman NMR structural studies of the human interferon-?2 complex with human Type I Interferon receptor – C3.03

Structural Biology,Weizmann Institute of Science, Rehovot, Israel


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15.30–17.00 Hall G2 Technology Workshop – Molecular Imaging

Chairperson: Hans Hebert (Stockholm)

15.30 Hans Hebert The tmRNA system for ribosome rescue: Single particle cryo electron microscopy, structural heterogeneity and difference map calculations – I52

Structural Biotechnology, Royal Institute of Technology, Huddinge Sweden

16.00 Roman A. Zubarev Novel “tomography” mass spectrometry tissue imaging method – I161

Department of Medicinal Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden

16.30 Dagmar Salber Imaged by LA-ICP-MS: Metal accumulations after cerebral infarct in course of time – A4.27

Institute of Neurosciences and Medicine, Forschungszentrum Jülich, Jülich, Germany

16.45 Jelena Markovic The nuclear compartimentation of glutathione: effect on cell cycle progression and chromatin condensation – D4.08

Core Research Facility, University of Valencia, Valencia, Spain

15.30–17.00 Hall G4 Technology Workshop – Network Modelling

Chairperson: Stefan Schuster (Jena)

15.30 Stefan Schuster Predicting pathways in genome-scale metabolic net-works – I122

Department of Bioinformatics, Friedrich-Schiller-University Jena, Jena, Germany

16.00 Brenda Andrews A comprehensive genetic-interaction map of a eukaryo-tic kinome – B3.12

Banting and Best Department of Medical Research, University of Toronto, Toronto, Canada

16.30 Marija Cvijovic Yeast Protein-Protein Interaction annotation – B3.14 Department of Chemical and Biological Engineering – Systems Biology, Chalmers University of Technology, Göteborg, Sweden

16.45 Carsten Kettner Reporting and capturing uniform enzyme function data – B1.01

Beilstein-Institut, Frankfurt, Germany

17.15–18.15 Congress Hall FEBS/EMBO Women in Science Award Lecture

Chairperson: Peter Herrlich (Jena)

Ingrid Grummt Wisely chosen paths: Regulation of ribosomal RNA synthesis – I46

Division of Molecular Biology of the Cell II, German Cancer Research Center, DKFZ-ZMBH Alliance, Heidelberg, Germany

Thursday, July 1, 2010

08.30–11.00 Congress Hall A – Molecules in Health and Disease. A5 – Infectious Diseases

Chairpersons: Viesturs Baumanis (Riga)

08.30 Ralf Bartenschlager New Insights into Hepatitis C Virus Replication and Persistence – I08

Department of Molecular Virology, University of Heidel-berg, Heidelberg, Germany

09.00 Wayne Hendrickson Ligand recognition and plasticity in HIV envelope glyco-protein gp120 – I53

Department of Biochemistry and Molecular Biophysics, Columbia University, New York, USA

09.30 Hans Wolf-Watz Yersinia blocks innate immunity via the TypeIII secretion system; A possible drug target for novel therapy? I156

Department of Molecular Biology, Umeå University, Umeå, Sweden

10.00 Pascale Cossart The bacterium Listeria monocytogenes: A brilliant cell biologist and an insidious biochemist – I25

Institut Pasteur, Paris, France

10.30 Shulamit Michaeli Trans-splicing is a regulated and is master regulator of trypanosome gene expression – I81

The Mina and Everard Goodman Faculty of Life Sciences, and Advanced Materials and Nanotechnology Institute, Bar-Ilan University, Ramat-Gan, Israel

08.30–11.00 Hall G3 B – Molecular Networks. B5 – Regulation of protein function

Chairpersons: Therese Jacobson (Göteborg)

08.30 Anne Simonsen Fighting disease by selective autophagy of aggregate-prone proteins – I128

Dept. of Biochemistry, University of Oslo, Oslo, Norway

09.00 Gerald W Hart Extensive crosstalk between O-GlcNAcylation and phos-phorylation: A new paradigm for cellular signaling? – I51

Department of Biological Chemistry,Johns Hopkins University School of Medicine, Baltimore, USA

09.30 Ivan Mijakovic Protein phosphorylation in bacteria – I82 MICALIS UMR 1319, AgroParisTech-INRA, Thiverval-Grignon, France

10.00 Davide F.V. Corona Functional interaction between chromatin remodelers and non-coding RNA’s – I24

Department of Cell and Developmental Biology, University of Palermo, Palermo, Italy

10.30 Piet Gros Mechanistic insights into complement activation and regulation – I45

Department of Chemistry, University of Utrecht, Utrecht, The Netherlands


08.30–11.00 Hall G2 C – Molecules at Work. C5 – Energy Transduction

Chairperson: Jan Rydström (Göteborg)

08.30 Ulrich Brandt Structural and functional insights into mitochondrial complex I – I19

Cluster of Excellence Frankfurt Macromolecular Complexes, Centre for Membrane Proteomics, Johann Wolfgang Goethe-Universität, Frankfurt am Main, Germany

09.00 Shelagh Ferguson-Miller Conformational changes seen in crystal structures of oxidized, reduced and mutant forms of cytochrome c oxidase: clues to coupling and gating mechanism? – I38

Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, USA

09.30 So Iwata Structure and mechanism of membrane transporters – I61

Division of Molecular Biosciences, Imperial College London, London, UK

10.00 Wolfram Saenger Photosystem II at 2.9 Ã resolution – Quinones, lipids, channels and chloride ion – I112

Institute for Chemistry and Biochemistry/Crystallography, Freie Universitaet Berlin, , Berlin, Germany

10.30 Peter Brzezinski Tuning the proton pumping stoichiometry in cytochrome c oxidase by single mutations – I21

Department of Biochemistry and Biophysics, The Arrhenius Laboratories for Natural Sciences, Stockholm University, Stockholm, Sweden

08.30–11.00 Hall G4 D – Cellular Compartments. D5 – Chloroplasts

Chairperson: Cecilia Hägerhäll (Lund)

08.30 Egbert Boekema Structure of chloroplast membrane organization using cryo-electron tomography – I16

Groningen Biomolecular Sciences and Biotechnology Insti-tute, University of Groningen, Groningen, The Netherlands

09.00 Eva-Marie Aro Electron transfer routes in photosynthetic membranes – Impact on biohydrogen production – I05

Plant Physiology and Molecular Biology, Department of Biochemistry and Food Chemistry, University of Turku, Turku, Finland

09.30 Holger Dau On the role of protons and O2 partial pressure in water oxidation by photosystem II – I27

Fachbereich Physik, Freie Universität Berlin, Berlin, Germany

10.00 Chris Bowler Genomics-enabled approaches for revealing the mo-lecular secrets of marine diatoms – I18

Centre National de la Recherche Scientifique (CNRS), UMR8186, Ecole Normale Supérieure, Paris, France

10.30 Ralph Bock Transgenic plastids as expression factories in biotech-nology – I15

Max-Planck-Institut für Molekulare Pflanzenphysiologie, Potsdam-Golm, Germany

0830–1100 Hall J1 E – Biomolecular Design and Function. E5 – Catalytic Mechanisms

Chairperson: Jaak Järv (Tartu)

08.30 Bengt Mannervik The quest for molecular quasi-species in ligand-activity space and its application to directed enzyme evolution – I76

Department of Biochemistry and Organic Chemistry, Uppsala University, Uppsala, Sweden

09.00 Donald Hilvert Teaching old enzymes new tricks – I55 Laboratory of Organic Chemistry, ETH Zürich, Zürich, Switzerland

09.30 Manfred Reetz Methodology development in directed evolution – I109 Max-Planck-Institut für Kohlenforschung, Mülheim an der Ruhr, Germany

10.00 Maria Joao Ramos Computational enzymatic catalysis – I108 Department of Chemistry, University of Porto, Porto, Portugal

10.30 Isabelle Moura The two terminal enzymes of denitrification: Nitric and nitrous oxide reductase – I83

Departement of Chemistry, Universidade Nova de Lisboa, Caparica, Portugal



Chairperson: Winnie Eskild (Oslo)

11.30 Venki Ramakrishnan What we have learned from structures of the ribosome – I107

Structural Studies Division, MRC Laboratory of Molecular Biology, Cambridge, UK

12.30–13.00 Congress Hall Closing Ceremony

14.00–17.00 Hall G4 FEBS Council Meeting


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32


33




Notes


34

DESIG

N: N

.FORM

, CO

VERPH

OTO

S: © 2005 C

LAES A

XSTÅ

L, PRINT: Inform

trycket, Göteborg, 2009.

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• More than 30,000 coding and non-synonymous SNPs

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