Journal of Neurology, Neurosurgery, Psychiatry r .4 ... · JournalofNeurology,Neurosurgery,...

Journal of Neurology, Neurosurgery, and Psychiatry } .4January 1985 Vol. 48 No. 1 C.ContentsWho goes home? Predictive factors in stroke recovery SUSAN HENLEY, SYLVLA PETTIT, ANDREW TODD-POKROPEK,ANNEMARIE TUPPER page 1Recovery after stroke: the first three months DERICK T WADE, VICTORINE A WOOD, RICHARD LANGTON HEWER page 7TECHNICAL NOTE

Stereotaxis and nuclear magnetic resonance LARS LEKSELL, DAN LEKSELL, JOHN SCHWEBEL page 14Visualisation of stereotactic radiolesions by nuclear magnetic resonance LARS LEKSELL, TORSTEN HERNER, DAN LEKSELL,BERTIL PERSSON, CHRISTER LINDQUIST page 19Residual complaints of patients two years after severe head injury AH VAN ZOMEREN, W VAN DEN BURG page 21Complex visual hallucinations in the hemianopic field HANSW KOLMEL page 29Digital subtraction angiography in patients with cerebral ischaemic attacks and normal continuous wave dopplerstudies M GUIDOTTI, G LANDI, G SCOTTI, G SCARLATO page 39Presentation and management of parasellar and suprasellar metastatic mass lesions JORGE C KATTAH, ROBERT M SILGALS,HERBERT MANZ, JAIME G TORO, ANATOLY DRITSCHILO, FREDERICK P SMITH page 44Cerebrospinal fluid vasopressin in neurological and psychiatric disorders PER SOELBERG S0RENSEN, ANNETTE GJERRIS,MOGENS HAMMER page 50Correlation between plasma fibrin-fibrinogen degradation product values and CT findings in head injurySHINSUKE UEDA, KAZUHIKO FUJITSU, HIDEYO FUJINO, TSUNEMI SEKINO, TAKEO KUWABARA page 58Basal ganglia calcification in Down's syndrome S TAKASHIMA, LE BECKER page 61Guillain-Barre syndrome following zimeldine treatment JAN FAGIUS, PER OLOF OSTERMAN, AKE SIDf-N,BENGT-ERIK WIHOLM page 65Mitochondrial malic enzyme in Friedreich's ataxia: failure to demonstrate reduced activity in culturedfibroblasts RGF GRAY, D KUMAR page 70A relationship between claudication of the cauda equina and the small aorta syndrome KR POSKITT, GD PERKIN,RM GREENHALGH page 75Unusual EEG patterns in coma, and their evolution DF SCOTT, RS SUMRA page 80SHORT REPORTS

Denervation in wasted hand muscles in a case of primary cerebellar ectopia without syringomyelia SM ALANI page 84Contralateral gaze deviation after frontal lobe haemorrhage JAMES A SHARPE, ROBERTA L BONDAR, WILLIAM A FLETCHERpage 86LETTERS

Central cord syndrome in an infant complicating inadvertent intraoperative stretching of the neckA NORMAN GUTHKELCH page 89Relapse of benign partial epilepsy of children in adulthood: report of a case GIOVANNI AMBROSETTO, PAOLO TINUPER,AGOSTINO BARUZZI page 90Left temporal lobe abscess presenting with an acute amnesic syndrome 28 years after contralateral temporal lobeabscess BA SIMPSON, M SWASH page 90MATrERS ARISING page 92BOOK REVIEWS page 94

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No 1 JANUARY 1985 PageWho goes home? Predictive factors in stroke recovery SUSAN HENLEY, SYLVIA PETrIT, ANDREW TODD-POKROPEK,ANNEMARIE TUPPER ...................................................................... 1

Recovery after stroke: the first three months DERICKTWADE, VICTORINEAWOOD, RICHARD LANGTON HEWER .. 7

TECHNICAL NOTE

Stereotaxis and nuclear magnetic resonance LARS LEKSELL, DAN LEKSELL, JOHN SCHWEBEL .... ............ 14Visualisation of stereotactic radiolesions by nuclear magnetic resonance LARS LEKSELL, TORSTEN HERNER,DAN LEKSELL, BERTIL PERSSON, CHRISTER LINDQUIST .............................................. 19Residual complaints of patients two years after severe head injury AHVANZOMEREN, WVANDENBURG ...... 21Complex visual hallucinations in the hemianopic field HANS WK6LMEL............................... 29Digital subtraction angiography in patients with cerebral ischaemic attacks and normal continuous wave dopplerstudies M GUIDOTTI, G LANDI, G SCOTTI, G SCARLATO ............................................. 39Presentation and management of parasellar and suprasellar metastatic mass lesions JORGECKATTAH,ROBERT M SILGALS, HERBERT MANZ, JAIMEG TORO, ANATOLY DRITSCHILO, FREDERICK P SMITH ................. 44Cerebrospinal fluid vasopressin in neurological and psychiatric disorders PER SOELBERG S0RENSEN,ANNETTE GJERRIS, MOGENS HAMMER .......................................................... 50Correlation between plasma fibrin-fibrinogen degradation product values and CT findings in head injurySHINSUKE UEDA, KAZUHIKO FUJITSU, HIDEYO FUJINO, TSUNEMI SEKINO, TAKEO KUWABARA .... ............... 58Basal ganglia calcification in Down's syndrome S TAKASHIMA, LE BECKER ............................ 61Guillain-Barre syndrome following zimeldine treatment JAN FAGIUS, PER OLOFOSTERMAN, AKE SIDEN,BENGT-ERIK WIHOLM .............. ....................................................... 65Mitochondrial malic enzyme in Friedreich's ataxia: failure to demonstrate reduced activity in cultured fibroblastsRGFGRAY, DKUMAR ..................................................................... 70A relationship between claudication of the cau4a equina and the small aorta syndrome KRPOSKITT, GDPERKIN,RMGREENHALGH ....... ................................................................. 75Unusual EEG patterns in coma, and their evolution DFSCOTT, RSSUMRA............................ 80

SHORT REPORTS

Denervation in wasted hand muscles in a case of primary cerebellar ectopia without syringomyelia SMALANI 84Contralateral gaze deviation after frontal lobe haemorrhage JAMES A SHARPE, ROBERTA L BONDAR,WILLIAM A FLETCHER ..................................................................... 86

LETTERS

Central cord syndrome in an infant complicating inadvertent intraoperative stretching of the neck ANORMANGUTHKELCH............................................................................ 89Relapse of benign partial epilepsy of children in adulthood: report of a case GIOVANNI AMBROSETTO,PAOLOTINUPER, AGOSTINO BARUZZI .......................................................... 90Left temporal lobe abscess presenting with an acute amnesic syndrome 28 years after contralateral temporal lobeabscess BA SIMPSON, M SWASH...................................................................... 90

MATTERS ARISING....................................................................... 92

BOOK REVIEWS..........................................................................94

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No 2 FEBRUARY 1985 PageOccasional reviewThe pre-morbid personality of patients with Parkinson's disease CJ TODES, AJ LEES..................... 97

The relationship between serum concentrations and central nervous system actions of metoprolol FM GENGO,JC ERMER, C CAREY, GC KALONAROS, WB MCHUGH ......................... 101

An assessment of 24-hour ambulatory EEG/ECG monitoring in a neurology clinic RE CULL............. 107

Fatal intracranial arterial dissection: clinical pathological correlation MICHAEL A FARRELL, JOSEPH I GILBERT,JOHN CE KAUFMANN...................-.-.-..1.......................1l

Herpes zoster ophthalmicus followed by contralateral hemiparesis: report of two cases and review of literatureELI RESHEF, STEPHEN B GREENBERG, JOSEPH JANKOVIC ...... ................. ...................... 122

Cervical nystagmus due to loss of cerebellar inhibition on the cervico-ocular reflex: a case report AM BRONSTEIN,JD HOOD............................................................................... 128

Incidence ofdelayed cerebral ischaemia following subarachnoid haemorrhage ofunknown cause PHILIP BARLOW 132

Neuropsychological evaluation of mild head injury MASSIMO GENTILINI, PAOLO NICHELLI, RUDOLF SCHOENHUBER,PAOLO BORTOLOTTI, LUIGI TONELLI, ANGELO FALASCA, GIAN A MERLI .................................. 137

Two basic properties of space representation in the brain: evidence from unilateral neglect EDOARDO BISIACH,ERMINIO CAPITANI, ENRICA PORTA............................................................ 141

Cerebellar degeneration in dominantly inherited spastic paraplegia CL SCHOLTZ, M SWASH .... ........... 145

SHORT REPORTS

Neurological findings in patients with the fragile-X syndrome PASQUALE F FINELLI, SIEGFRIED M PUESCHEL,TERESITA PADRE-MENDOZA, MARK M O'BRIEN ........................... ......................... 150

Vitamin B nutrition in Nigerian tropical ataxic neuropathy BO OSUNTOKUN, A ALADETOYINBO, 0 BADEMOSI ... 154

Intravenous methylprednisolone for multiple sclerosis in relapse MP BARNES, DE BATEMAN, PG CLELAND, DJ DICK,TJ WALLS, PK NEWMAN, M SAUNDERS, PJB TILLEY ................................................ 157

Outcome from 'rescue clipping' of ruptured intracranial aneurysms during induction anaesthesia andendotracheal intubation SATSEMENTZIS, ER HITCHCOCK .......................................... 160

Pseudotumour cerebri and the Turner syndrome VIRGINIA P SYBERT, THOMAS D BIRD, DARRELL J SALK ...... 164

Hypotrophy of type I fibres with central nuclei: recovery 4 years after diagnosis JOSt R RICOY, ANA CABELLO 167

Neurological involvement in type 1 (adult) Gaucher's disease RO MCKERAN, P BRADBURY, D TAYLOR, G STERN 172The effect of skin temperature on vibratory sensitivity in polyneuropathy RICHARD TEGNR.............. 176

Polyneuropathy due to polyangiitis overlap syndrome LHTHS KORTBEEK, MWPM VAN BEEK .... ........... 179

The effects of conditioning stimuli on the F-response FL MASTAGLIA, WM CARROLL..................... 182

LETTERS

Epilepsy: an early symptom of systemic lupus erythematosus CG MACKWORTH-YOUNG, GRV HUGHES ....... 185Unusual features in a case of bilateral paramedian thalamic infarction G KARABELAS, N KALFAKIS, I KASVIKIS,D VASSILOPOULOS........................................................................ 186

Focal seizures with reversible hypodensity on the CT scan D ZEGERS DE BEYL, N HERMANUS, H COLLE, S GOLDMAN 187

Transient hemiparesis - a cautionary tale: coexistence of phaeochromocytoma and intracranial aneurysmAN JHA, RH LYE......................................................................... 188

Hemifacial spasm associated with a mixed benign parotid tumour A DESTEE, B BOUCHEZ, Ph PELLEGRIN,P WAROT.............................................................................. 189

Recurrent intracranial haemorrhage in Behcet disease KEN NAGATA ................. .. ................. 190

MATTERS ARISING................................................................................. 192

BOOK REVIEWS.................................................................................... 196

LIST OF ASSESSORS AND BOOK REVIEWERS .............................................................. 199



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No 3 MARCH 1985 PageA study of cerebral blood flow and metabolism in epileptic psychosis using positron emission tomography andoxygen B GALLHOFER, MR TRIMBLE, R FRACKOWIAK, J GIBBS, T JONES ................................ 201Pantomime comprehension and ideomotor apraxia LESLIE J GONZALEZ ROTHI, KENNETH M HEILMAN,ROBERT T WATSON....................................................................... 207Brain atrophy in chronic alcoholic patients: a quantitative pathological study CLIVE HARPER, JILLIAN KRIL . . 211Hereditary whispering dysphonia NEVILLE PARKER ............................................. 218Vasopressin secretion in progressive autonomic failure: evidence for defective afferent cardiovascular pathwaysTDM WILLIAMS, SL LIGHTMAN, R BANNISTER .................................................... 225The effect of lithium on choline transport in human erythrocytes JB UNEY, RM MARCHBANKS, A MARSH ...... 229Familial clustering of the ataxic form of Creutzfeldt-Jakob disease with hirano bodies L CARTIER, S GALVEZ,DC GAJDUSEK............................................................................ 234The pathological basis of conduction block in human neuropathies TE FEASBY, WF BROWN, JJ GILBERT,AF HAHN......................................................................................... 239Phrenic nerve conduction time in Guillain-Barresyndrome M GOUREE-DEVI, GR GANAPATHY.............. 245Orthodromic sensory action potentials from palmar stimulation in the diagnosis of carpal tunnel syndromeKR MILLS.............................................................................. 250Ultrastructure of cerebral arteries following experimental subarachnoid haemorrhage JD PICKARD, DI GRAHAM,ELIZABETH MATEAR, P MacPHERSON, A TAMURA, W FITCH .......................................... 256Small cerebellar strokes may mimic labrynthine lesions CY HUANG, YL YU ........................... 263

SHORT REPORTS

Distal amyotrophy of predominantly the upper limbs with pyramidal features in a large kinship EM VAN GENT,RA HOOGLAND, FGI JENNEKENS .............................................................. 266Inclusion body myositis: a case with associated collagen vascular disease responding to treatment RJM LANE,IJ FULTHORPE, P HUDGSON................................................................. 270A note on the mechanism of resistance to anoxia and ischaemia in pathophysiological mammalian myelinatednerve JM RITCHIE........................................................................ 274Positive bromide partition test in the absence of tuberculous meningitis JR WEINBERG, SP COPPACK ........ 278

LETTERSThe cytopathogenic agent in CSF: evidence for a relationship with enolase levels GR TAYLOR, GW ROBERTS,TJ CROW, JA ROYDS, SJ GAMBLE, CB TAYLOR, GI CARTER, WR TIMPERLEY ............................... 281Computed tomography and acute carbon monoxide poisoning A DESTEE, V COURTEVILLE, Ph DEVOS, P BESSON,PWAROT.............................................................................. 281Isoniazid and action tremor in multiple sclerosis JAMES- MORROW, HELEN MCDOWELL, CATHERINE RITCHIE,VICTOR PATTERSON ...................................................................... 282Drug-induced alpha coma RAHMAN POURMAND, OKMAR N MARKAND................................ 283Development of tolerance to anticonvulsant effect of clobazam JW ALLEN, S JAWAD, J OXLEY, M TRIMBLE.... 284Juvenile muscular atrophy of distal upper extremities CT TAN .................................... 285The effects of magnetic resonance imaging on different types of microsurgical clips DM KEAN, BS WORTHINGTON,JL FIRTH, RC HAWKES..................................................................... 286Rapid enlargement of non-functioning pituitary tumour following withdrawal of bromocriptine IDA CLARK,T WHEATLEY, OM EDWARDS ................................................................ 287Prolactin cell autoantibodies and Alzheimer's disease M PHILPOT, J COLGAN, R LEVY, A HOLLAND, R MIRAKIAN,CA RICHARDSON, GF BOTTAZZO.............................................................. 287Spinal angiomatosis presenting as a sensory neuropathy RAC HUGHES, CWM ADAMS ... ................. 288Cephalic tetanus presenting with Bell's palsy J MAYO, J BERCIANO.................................. 290Unmasking of cerebellar tumours by amitriptyline in depressive patients JOSE MARTIN RABEY, ELIESER AVRAHAMI 291



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NOTICE ............................................................................... 291

MATTERS ARISING.292

BOOK REVIEWS.293

No 4 APRIL 1985OCCASIONAL REVIEW

The limbic system and the localisation of herpes simplex encephalitis ANTONIO R DAMASIO, GARY W VAN HOESEN 297

Intramedullary spinal cord glioma with intracranial seeding M HELY, J FRYER, G SELBY.302Blood flow and oxygen utilisation in the contralateral cerebral cortex of patients with untreated intracranialtumours as studied by positron emission tomography, with observations on the effect of decompressivesurgery RONALD P BEANEY, DAVID J BROOKS, KLAUS L LEENDERS, DAVID GT THOMAS, TERRY JONES, KEITH E HALNAN 310

Morbidity and mortality in motor neuron disease: comparison with multiple sclerosis and Parkinson's disease: ageand sex specific rates and cohort analyses TING-MING LI, MICHAEL SWASH, EVA ALBERMAN.320

Serum dopamine f3-hydroxylase activity in menstrual migraine AL MAGOS, M BRINCAT, KJ ZILKHA, JWW STUDD 328

Thymectomy in myasthenia with pure ocular symptoms F SCHUMM, H WIETHOLTER, A FATEH-MOGHADAM,J DICHGANS ............................................................................ 332

Contralateral hemiparesis following herpes zoster ophthalmicus CHRISTINE GASPERETTI, SUN KYU SONG.338

Cerebellar atrophy due to chronic bromisovalum abuse demonstrated by computed tomographyAJLM VAN BALKOM, BJM VAN DE WETERING, DLJ TAVY, REM HEKSTER, TCAM VAN WOERKOM.342

Computed tomographic correlates of auditory brainstem responses in alcoholics NAI-SHIN CHU.348

An improved automated method for the measurement ofthermal thresholds. 1. Normal subjects. GORAN A JAMAL,STIG HANSEN, ANDREW I WEIR, JOHN P BALLANTYNE.354

An improved automated method for the measurement of thermal thresholds. 2. Patients with peripheralneuropathy GORAN A JAMAL, ANDREW I WEIR, STIG HANSEN, JOHN P BALLANTYNE .... ..................... 361

Visual evoked potentials to lateralised stimuli in two cases of callosal agenesis MICHAEL D RUGG, A DAVID MILNER,CHRISTOPHER R LINES.367

The interaction of denzimol (a new anticonvulsant) with carbamazepine and phenytoin PN PATSALOS,SD SHORVON, AA ELYAS, G SMITH ......................; . ............... 374

SHORT REPORTS

The spoon test: a simple bedside test for assessing sudomotor autonomic failure SA TSEMENTZIS, ER HITCHCOCK 378

Calcium channel antagonism by pizotifen STEPHEN J PEROUTKA, SUZANNE B BANGHART, GEORGES ALLEN.381

LETTERS

Painful arm and moving fingers WIM VERHAGEN, MWIM HORSTINK, SLH NOTERMANS.384

The arm-mouth reflex in a patient with amyotrophic lateral sclerosis K KURODA, K ODA, H SHIBASAKI 385

Triphasic spike-wave stupor in portal-systemic encephalopathy: a case report MITSUTOSHI YAMAMOTO, KIYOSHIHOSOKAWA.386

Low-dose bromocriptine in Parkinson's disease IRIS PEARCE, JMS PEARCE.388

NOTICES.389

MATTERS ARISING.390

BOOK REVIEWS.......................................................................... 392



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No 5 MAY 1985 PageOCCASIONAL REVIEW

"Depressive pseudodementia" or "Melancholic dementia": a 19th century view GE BERRIOS .............. 393The long term experience of thymectomy for myasthenia gravis GK SCADDING, CWH HARVARD, MJ LANGE, I DOMB 401Spared musical abilities in a conductor with global aphasia and ideomotor apraxia ANNA BASSO, ERMINIO CAPITANI 407Cholinergic correlates of cognitive impairment in Parkinson's disease: comparisons with Alzheimer'sdisease ELAINE K PERRY, MICHAEL CURTIS, DAVID J DICK, JOHN M CANDY, JOHN R ATACK, CLIVE A BLOXHAM, GARRYBLESSED, ANDREW FAIRBAIRN, BERNARD E TOMLINSON, ROBERT H PERRY................................ 413Neuronal distribution in the putamen in Huntington's disease RAC ROOS, JFM PRUYT, J DE VRIES, GTAM BOTS ... 422Huntington's disease: visuomotor disturbance in patients and offspring G OEPEN, U MOHR, K WILLMES, U THODEN 426Electroneurographic correlates of the monosynaptic reflex: experimental studies and normative dataMICHELE ABBRUZZESE, SANDRO RATTO, GIOVANNI ABBRUZZESE, EMILIO FAVALE ............................ 434The flexor carpi radialis H-reflex in lesions of the sixth and seventh cervical nerve roots RJ SCHIMSHEIMER,BW ONGERBOER DE VISSER, B KEMP ............................................................ 445Protection of respiration of a crude mitochondrial preparation in cerebral ischaemia by control of bloodglucose AJ STRONG, SUSIE A MILLER, IC WEST ................................................... 450Rhino-orbital zygomycosis CJK ELLIS, SE DANIEL, PG KENNEDY, SM OPPENHEIMER, F SCARAVILLI.............. 455Antiepileptic and antiamnesic effect of carbamazepine in experimental limbic epilepsy CATHERINE A HAWKINS,JANE MELLANBY, J BROWN .................................................................. 459

SHORT REPORTSPutative amino acid transmitters in lumbar cerebrospinal fluid of patients with histologically verified Alzheimer'sdementia CCT SMITH, DM BOWEN, PT FRANCIS, JS SNOWDEN, D NEARY ................................. 469Toxic "ictal" confusion in middle age: treatment with benzodiazepines B VAN SWEDEN .... .............. 472

Intramedullary sarcoidosis of the cervical spinal cord ALAIN VIGHETTO, GEORGES FISCHER, PHILIPPE COLLET,BERNADETTE BADY, MARC TRILLET ............................................................ 477Status epilepticus, hypothermia and metabolic chaos in a man with agenesis of the corpus callosum MH JOHNSON,SN JONES............................................................................... 480Hyperkalaemic paralysis following traumatic rupture of the urinary bladder HITOSHI SHINOTOH,TAKAMICHI HATTORI, KUNITAKA KITANO, JOJI SUZUKI ...... .................. ...................... 484

LETTERS

Vertebrobasilar insufficiency in a patient with anomaly of the thyroscapular trunk: an unusual stealsyndrome? B BOUCHEZ, GE ARNOTT, E DELANDSHEER, G GOZET, M RIBET, B HUBSCHMAN, P LESTAVEL .... ....... 486Familial writer's cramp P MARTiNEZ-MARTiN, F BERMEJO PAREJA .................................... 487Asterixis due to pontine haemorrhage YUTAKA KUDO, MITSUHIRO FUKAI, ATSUSHI YAMADORI .... .......... 487

CORRECTION ............................................................................ 489

MATTERS ARISING........................................................................ 489

BOOK REVIEWS.......................................................................... 491

No 6 JUNE 1985Hyperbaric oxygen in chronic progressive multiple sclerosis: visual evoked potentials and clinical effectsJACK NEIMAN, BENGT Y NILSSON, PER 0 BARR, DAVID JD PERRINS ....................................... 497Circulating T cell subsets in the Lambert-Eaton myasthenic syndrome STEPHANIE A ROBB, TERRY J BOWLEY,H NICHOLAS A WILLCOX, JOHN NEWSOM-DAVIS........................................... ........ 501Primary generalised epileptic myoclonus: a frequent manifestation of minipolymyoclonus of centralorigin DE WILKINS, M HALLETT, GERBA ....................................................... 506The effect of Parkinson's disease on the ability to maintain a mental set KAFLOWERS, C ROBERTSON........ 517



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PageLate onset of Huntington's disease RICHARD H MYERS, DANIEL S SAX, MIRIAM SCHOENFELD, EDWARD D BIRD,PHILIP A WOLF, JEAN PAUL VONSATTEL, ROBERTA F WHITE, JOSEPH B MARTIN.530Tonic, phasic and cortical arousal in Gilles de la Tourette's syndrome RICHARD D BOCK, LEO GOLDBERGER ... 535Writing tremor: its relationship to benign essential tremor T KACHI, JC ROTHWELL, JMA COWAN, CD MARSDEN. . 545The relationship of transient hemiparesis following febrile convulsions in infancy to subsequent temporallobectomy for intractable seizures A DARKINS, CE POLKEY ........................................ 551Impairment of remote memory after closed head injury HARVEY S LEVIN, WALTER M HIGH, CHRISTINA A MEYERS,ALEXANDER VON LAUFEN, MARY ELLEN HAYDEN, HOWARD M EISENBERG.................................. 556Social adjustment after closed head injury: a further follow-up seven years after injury MICHAEL ODDY,TONY COUGHLAN, ANDREW TYERMAN, DAVID JENKINS.............................................. 564

Five-year neurological and EEG outcome after open-heart surgery KA SOTANIEMI...................... 569

SHORT REPORTSPeripheral neuropathy during longterm high-dose amiodarone therapy AG FRASER, INF MCQUEEN, AH WATT,MR STEPHENS............................................................................ 576

Sacral sparing with cauda equina compression from central lumbar intervertebral disc prolapse DJ LAFUENTE,JANDREW, AJOY........................................................................ 579Brachial plexus myoclonus G BANKS, VK NIELSEN, MP SHORT, CD KOWAL.............................. 582Levodopa and melanoma: three cases and review of literature FRANS HJ RAMPEN ....................... 585

Germinoma of the pituitary gland; a report of two cases J ANDREW, BE KENDALL, CD BROOK... ........... 589

LETTERAcute polyneuritis with cranial nerve involvement following Campylobacter jejuni infection SJ WROE,LD BLUMHARDT . ........................................................................ 593

Proceedings of Society of the British Neurological Surgeons ...................................... 594

Proceedings of the Association of British Neurologists........................................... 601MATTERS ARISING.................................................................................. 606BOOK REVIEWS .......................................................................... 608

No 7 JULY 1985Rehabilitation after severe brain injury: a follow-up study of a behaviour modification approach PETER EAMES,RODGER WOOD.................................................................................... 613Syringoperitoneal shunt for treatment of cord cavitation MIKIO SUZUKI, CHARLES DAVIS, LINDSAY SYMON, F GENTILI 620Pellagra encephalopathy among tuberculous patients: its relation to isoniazid therapy NOBUYOSHI ISHII,YASUO NISHIHARA.................................................................................. 628Human monoclonal anti-MAG antibody and anti-Leu 7 recognise shared antigenic determinants in peripheralnerve and spinal cord GUIDO STOLL, GUNTHER SCHWENDEMANN, KURT HEININGER, ANDREAS J STECK, KLAUS V TOYKA 635A prospective study between carbamazepine, phenytoin and sodium valproate as monotherapy in previouslyuntreated and recently diagnosed patients with epilepsy N CALLAGHAN, RA KENNY, B 0 NEILL, M CROWLEY,TGOGGIN ....................................................................................... 639Absence of enhanced physiological tremor in patients without muscle or cutaneous afferents JEROME N SANES 645Hemidystonia: a report of 22 patients and a review of the literature L CREED PETTIGREW, JOSEPH JANKOVIC.... 650Pontine haemorrhage: a clinical analysis of 26 cases SHOJI MASIYAMA, HIROSHI NIIZUMA, JIRO SUZUKI.......... 658The effects of hyperglycaemia on changes during reperfusion following focal cerebral ischaemia in the catGS VENABLES, SUSIE A MILLER, G GIBSON, JA HARDY, AJ STRONG ............................................. 663Reversible abnormalities of the Hering Breuer reflex in acrylamide neuropathy PAUL SATCHELL............. 670Chronic transformation of muscle in spasticity: a peripheral contribution to increased tone A HUFSCHMIDT,K-H MAURITZ .................................................................................... 676Thermal discrimination thresholds in normal subjects and in patients with diabetic neuropathy FW BERTELSMANN,JJ HEIMANS, EJM WEBER, EA VAN DER VEEN, JA SCHOUTEN ................................................... 686



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Electrophysiological studies in the post-viral fatigue syndrome GORAN A JAMAL, STIG HANSEN ..... .......... 691Cerebellar ataxia in enteric fever RS WADIA, NR ICHAPORIA, RS KIWALKAR, RB AMIN, HV SARDESAI .... ......... 695The relationship of peripheral trauma and pain to dystonia GD SCHOTT ................................ 698Reaction time of patients with Parkinson's disease, with reference to asymmetry of neurological signsFUSAKO YOKOCHI, RYUICHI NAKAMURA, HIROTARO NARABAYASHI .......................................... 702Peripheral polyneuropathy and monoclonal gammopathy of undetermined significance MJ KROL-V STRAATEN,RGA ACKERSTAFF, CEM DE MAAT ................. .................................................... 706The value of the measurement of cerebrospinal fluid levels of lysozyme in the diagnosis of neurologicaldisease G FIRTH, J REES, RO MCKERAN ............. .................................................. 709

LETTERS

Neuropsychological functions in the follow-up of transient global amnesia J MATIAS-GUIU, ACODINA.713

Neuropsychiatric symptoms in the course of Wegener's granulomatosis IG MCKEITH ......... .. ........... 713Chronic meningitis in Fabry's disease JJ DUBOST, IL VIALLARD, BSAUVEZIE .............. .. ............... 714Acute acquired toxoplasmosis causing neuroptico-meningoencephalitis in an immunocompetent boyC CONFAVREUX, P GIRARD-MADOUX, T MOULIN, D BOISSON, A VIGHETTO, G AIMARD, M DEVIC ..... ............... 715"True" cystic meningioma ANTONIO RUELLE, ENRICO MARIOTTI, MASSIMILIANO BOCCARDO ..... .............. 716Stroke due to atrial myxoma in a young woman with co-existing acoustic neuroma and pituitary adenomaP GORMAN, R LANGTON HEWER...................................................................... 718Myasthenia gravis associated with a hormone producing malignant carcinoid tumour SJ WROE, M ARDRON,AN BOWDEN ..................................................................................... 719Multiple adverse reactions following metrizamide myelography C PASCHALIS, C SOTIRIADOU, D SIABLIS,Th PAPAPETROPOULOS.............................................................................. 720The role of childbirth on the natural history of occult spinal dysraphism J DE KEYSER, G EBINGER, L CALLIAUW 721Paraspinal myoclonus due to spinal root lesion KA SOTANIEMI ......................................... 722Failure to promote spinal cord regeneration in rats with immunosuppressive treatment EARL R FERINGA,H LEE VAHLSING, WAYNE J GILBERTIE ............. .................................................... 723MATTERS ARISING .................................................................................. 725NOTICE ...................................................................................... 725BOOK REVIEWS ................................................................................... 726

No 8 AUGUST 1985Motorist's vestibular disorientation syndrome NGR PAGE, MA GRESTY ................................... 729A double-blind, placebo controlled trial of high-dose lecithin in Alzheimer's disease ADRIENNE LITTLE, RAYMONDLEVY, PAZ CHUAQUI-KIDD, DAVID HAND ............ .................................................. 736Spontaneous recovery oflanguage in patients with aphasia between 4 and 34 weeks after stroke WENDY LENDREM,NADINA B LINCOLN................................................................................ 743Combined scatter diagrams of sheath thickness and fibre calibre in human sural nerves: changes with age andneuropathy RL FRIEDE, W BEUCHE ............. .................................................... 749Myasthenia gravis: long-term prognostic value ofthymus lactate dehydrogenase isoenzyme pattern of hyperplasticthymus and thymoma ISTVAN SZATHMARY, LASZL6 SELMECI, ELEK P6SCH, ALBERT SZOBOR, JANOS MOLNAR .... 757Bladder dysfunction in distal autonomic neuropathy of acute onset ROGER S KIRBY, CLARE J FOWLER, JOHN AGOSLING, ROGER BANNISTER........................................................................ 762Facial reflex examination for assessment of trigeminal nerve involvement in pituitary fossa tumours OLOF BYNKE- 768Effects of chronic low frequency electrical stimulation on normal human tibialis anterior muscle OM SCOTT,G VRBOVA, SA HYDE, V DUBOWITZ ................................................................... 774Increased co-activation of the upper limb muscles in writer's cramp M HUGHES, DL MCLELLAN ............. 782



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PageThe variation of finger tremor with age in man AT BIRMINGHAM, HI WHARRAD, EJ WILLIAMS.788Neurological and neuropsychological effects of cerebral spinal fluid shunting in children with assumed arrested("normal pressure") hydrocephalus RICHARD D TORKELSON, LYAL G LEIBROCK, JOHN L GUSTAVSON, ROBERT RSUNDELL.799Cerebrospinal fluid immunoglobulin abnormalities in systemic lupus erythematosus JAN ERNERUDH, TOMASOLSSON, FOLKE LINDSTROM, THOMAS SKOGH.807Cerebellar calcification and lead MD BENSON, J PRICE.814Usefulness of intraoperative cortical blood flow measurement by heat clearance method for monitoring cerebralischaemia during therapeutic carotid ligation T HAYAKAWA, K YAMADA, Y IWATA, A KATO, T YOSHIMINE, Y USHIO,S NAKATANI, T IKEDA, H MOGAMI.819Simulated paraplegia: an occasional problem for the neurosurgeon RS MAURICE-WILLIAMS, H MARSH.826

SHORT REPORTS

The effect of spinal cord stimulation on idiopathic detrusor instability and incontinence: a case report DJ READ,ED JAMES, C SHALDON.832Prognostic significance of serum a,-acid glycoprotein in patients with glioblastoma multiforme: a preliminarycommunication HIROSHI MATSUURA, SHOZO NAKAZAWA.835Pain in motor neuron disease PG NEWRICK, R LANGTON-HEWER.838

LETTERS

CT brain scan in acute water intoxication VLADIMIR M BERGINER, ALICIA OSIMANI, JULIA BERGINER, ELISHA BARMEIR 841Cortical vasoactive intestinal peptide in relation to dementia in Parkinson's disease S JEGOU, F JAVOY-AGID,C DELBENDE, M RUBERG, H VAUDRY, Y AGID .......................................................... 842Acute myelopathy in a drug abuser following an attempted neck vein injection RANGANNA KISHOREKUMAR,PRATAP YAGNIK, VASANT DHOPESH.................................................................. 843Solitary neurofibroma of the lumbosacral plexus A ARGYRAKIS, A TEICHMANN, W KUHN .... ............... 844MATTERS ARISING................................................................................. 847BOOK REVIEWS................................................................................... 850

No 9 SEPTEMBER 1985OCCASIONAL REVIEWCryptococcal meningitis TJOEI LIAN TJIA, YEW KIM YEOW, CHAI BENG TAN ............................... 853

MAIN PAPERS

Multiple sclerosis in research workers studying swayback in lambs: an updated report G DEAN, El MCDOUGALL,M ELIAN ......................................................................................... 859

Appearing and disappearing CT scan abnormalities and seizures PK SETHI, BR KUMAR, VS MADAN, V MOHAN 866Three months after severe head injury: psychiatric and social impact on relatives MARTIN G LIVINGSTON,D NEIL BROOKS, MICHAEL R BOND ............ ....................................................... 870Patient outcome in the year following severe head injury and relatives' psychiatric and social functioningMARTIN G LIVINGSTON, D NEIL BROOKS, MICHAEL R BOND ............................................... 876Tubular aggregates: their association with myalgia ENAYAT NIAKAN, YADOLLAH HARATI, MORIS J DANON ..... 882The rigid spine syndrome: a myopathy of uncertain nosological position W POEWE, H WILLEIT, E SLUGA, U MAYR 887A clinical and electrophysiological study of patients with polychlorinated biphenyl poisoning LIE-GANCHIA,FU-LI-CHU ............................................ 894Mortality and stroke after amaurosis fugax CJM POOLE, RW ROSS RUSSELL ............................... 902

Sensory involvement in motor neuron disease: further evidence from automated thermal threshold determinationGORAN A JAMAL, ANDREW I WEIR, STIG HANSEN, JOHN P BALLANTYNE ..................................... 906Primidone in essential tremor of the hands and head: a double blind controlled clinical study LESLIE J FINDLEY,LYNN CLEEVES, STEPHANO CALZETTI ................................................................. 911



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Parkinson's disease and Alzheimer's disease: hypersensitivity to X-rays in cultured cell lines JAY H ROBBINS,FUJIO OTSUKA, ROBERT E TARONE, RONALD J POLINSKY, ROGER A BRUMBACK, LINDA E NEE .... ................ 916

SHORT REPORTS

Immunohistological study of granulovacuolar degeneration using monoclonal antibodies to neurofilamentsJ KAHN, BH ANDERTON, A PROBST, J ULRICH, MARGARET M ESIRI .......................................... 924Passive transfer studies in demyelinating neuropathy with IgM monoclonal antibodies to myelin associatedglycoprotein ANDREAS J STECK, NORMAN MURRAY, JEAN-CLAUDE JUSTAFRE, CLAUS MEIER, KLAUS V TOYKA,KURT HEININGER, GUIDO STOLL..................................................................... 927

Clinical evaluation of 4-channel ambulatory EEG monitoring in the management of patients with epilepsyJOLYON OXLEY, MARGARET ROBERTS ............. .................................................... 930

A study of the effects of isaxonine on vincristine-induced peripheral neuropathy in man and regeneration followingperipheral nerve crush in the rat PAMELA M LE QUESNE, CLARE J FOWLER, ANITA E HARDING .... ............ 933

Familial syringomyelia NEIL A BUSIS, FRED H HOCHBERG .............................................. 936

The Marin-Amat syndrome: an unusual facial synkinesia PVS RANA, RS WADIA ..... ..................... 939

Pachymeningitis cranialis hypertrophica AP MOORE, EB ROLFE, EL JONES ................................. 942

Giant cell arteritis with spinal cord infarction and basilar artery thrombosis WRG GIBB, PAULINE A URRY, AJ LEES 945A case of granulomatous hypophysitis with hypopituitarism and minimal pituitary enlargement PATRICEHASSOUN, ELYAS ANAYSSI, IBRAHIM SALTI ........... .................................................. 949

LETTERS

Midbrain locked-in state with oculomotor subnucleus lesion DAISUKE UEMATSU, MAKOTO SUEMATSU, YASUOFUKUUCHI, SHIN-ICHIRO EBIHARA, FUMIO GOTOH ....................................................... 952Fluid chronic epidural haematoma: a rare complication of ventriculo-peritoneal shunt CHUNG P YUE,KIRPAL S MANN .................................................................................. 953Germinoma in the cerebellopontine angle K NAGENDRAN, M RICE-EDWARDS, B KENDALL, RO BARNARD, RJ GUILOFF 955Transient global amnesia after whiplash trauma HAKON HOFSTAD, IVAR OTTO GJERDE ..... ................ 956MATTERS ARISING ................................................................................. 957NOTICE ..................................................................................... 957BOOK REVIEWS ................................................................................... 958

No 10 OCTOBER 1985OCCASIONAL REVIEW

Scotland: the birthplace of surgical neurology PAUL C BUCY .......................................... 965

MAIN PAPERS

The influence of physostigmine on visual-vestibular interaction in hereditary ataxias CC TIJSSEN, U ENDTZ, C GOOR 977Lesions of the optic radiations mimicking lateral geniculate nucleus visual field defects JOHN E CARTER,PATRICK O'CONNOR, DAVID SHACKLETT, MICHAEL ROSENBERG ............................................ 982

Suspected and clinically definite multiple sclerosis: the relationship between CSF immunoglobulins and clinicalcourse ALAN J THOMPSON, MICHAEL HUTCHINSON, EDWARD A MARTIN, MAURA MANSFIELD, ALEX WHELAN,CONLETH FEIGHERY................................................................................ 989Free light chains in the cerebrospinal fluid: an iAdicator of recent immunological stimulation A VAKAET,EJ THOMPSON .................................................................................... 995

The near-nerve sensory nerve conduction in tarsal tunnel syndrome SHIN J OH, HYUN S KIM, BASHIRUDDIN K AHMAD 999Decelerating burst and complex repetitive discharges in the striated. muscle of the urethral sphincter, associatedwith urinary retention in women CLARE J FOWLER, RS KIRBY, MJG HARRISON ............................. 1004Complex partial seizures: EEG foci and response to carbamazepine and sodium valproate AK GUPTA, PM JEAVONS 1010



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PageNeuropathy and myopathy in two patients with anorexia and bulimia nervosa R ALLOWAY, EH REYNOLDS,E SPARGO, GFM RUSSELL........................................................................... 1015Autonomic nervous system dysfunction in workers exposed to organic solvents ESKO MATIKAINEN, JUHANIJUNTUNEN.1021Autonomic neuropathy in acute intermittent porphyria AC YEUNG LAIWAH, GJA MACPHEE, P BOYLE, MR MOORE,A GOLDBERG.................................................................................... 1025Differential effects of alpha-adrenoceptor blockade on essential, physiological and isoprenaline-induced tremor:evidence for a central origin of essential tremor B ABILA, JF WILSON, RW MARSHALL, A RICHENS.1031A dominantly inherited lower motor neuron disorder presenting at birth with associated arthrogryposis P FLEURY,C HAGEMAN ...................................................................................... 1037

SHORT REPORTS

Luria's frontal lobe syndrome: psychological and anatomical considerations AGM CANAVAN, I JANOTA, PH SCHURR 1049Granulomatous angiitis of the central nervous system: a case with recurrent intracerebral haemorrhageRE CLIFFORD-JONES, S LOVE, N GURUSINGHE ........................................................... 1054Rhabdomyolysis and concomitant neurological lesions after intravenous heroin abuse J DE GANS, J STAM,GK VAN WIJNGAARDEN............................................................................. 1057Plasma catecholamines in Down's syndrome, at rest and during sympathetic stimulation G UDESCHINI, G CASATI,F BASSANI, GB PICOTTI, P CULOTTA .............. .................................................... 1060Suppressor T cell changes in active multiple sclerosis: analysis with three different monoclonal antibodiesAJ THOMPSON, J BRAZIL, EA MARTIN, M HUTCHINSON, CA WHELAN, C FEIGHERY ............................. 1062Spinal cord lesions in heat stroke GABRIEL DELGADO, TERESA TUN6N, JAIME GALLEGO, JOSE A VILLANUEVA .... 1065

LETTERS

Postoperative salmonella meningitis: successful treatment with cefotaxime PAUL MOEST, JEAN-LOUIS VINCENT,JEAN-PIERRE THYS, JACQUES NOTERMAN, JACQUES BERRE, ROBERT J KAHN ................................... 1068High-resolution CT scan in pontine ataxic hemiparesis GABRIEL DELGADO, JAIME GALLEGO, JOSE LUIS ZUBIETA 1069Pseudoankylosis of the mandible following a fronto-temporal craniotomy MYM ZAFARULLA.1069MATTERS ARISING.................................................................................. 1070BOOK REVIEW .................................................................................... 1072

No II NOVEMBER 1985OCCASIONAL REVIEW

The comparative efficacy of antiepileptic drugs for partial and tonic-clonic seizures D CHADWICK, DM TURNBULL 1073

MAIN PAPERS

Subcortical lobar intracerebral haemorrhages: clinical-computed tomographic correlations LEON A WEISBERG 1078Validity of clinical diagnosis in dementia: a prospective clinicopathological study PEKKA K MOLSA, LEO PALJARVI,JUHA 0 RINNE, URPO K RINNE, ERKKI SAKO ........................................................... 1085Positron emission tomography with [18F] fluorodoeoxyglucose differentiates normal pressure hydrocephalus fromAlzheimer-type dementia WILLIAM J JAGUST, ROBERT P FRIEDLAND, THOMAS F BUDINGER.1091A study of the relationship between neurological function and serum vitamin E concentrations in patients withcystic fibrosis HJ WILLISON, DPR MULLER, S MATTHEWS, S JONES, A KRISS, RlSTEAD, ME HODSON, AEHARDING 1097A quantitative study of intermediolateral column cells in motor neuron disease and the Shy-Drager syndromePGE KENNEDY, LW DUCHEN ...................... .................................................. 1103Brain-stem auditory evoked responses in chronic alcoholics Y-WCHAN, JG MCLEOD, RR TUCK, PA FEARY 1107Visual field rehabilitation in the cortically blind? RICHARD BALLIET, KATHERINE MT BLOOD, PAUL BACH-Y-RITA 1113Pattern and flash evoked potentials in the assessment and management of optic nerve gliomas zGROSWASSER,A KRISS, AM HALLIDAY, WI MCDONALD ............... ................................................ 1125



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PageMotor conduction velocity in the human spinal cord: slowed conduction in multiple sclerosis and radiationmyelopathy SJ SNOOKS, M SWASH ............... ................................................... 1135Verapamil-induced perturbations of central conduction in patients with multiple sclerosis ROBIN L GILMORE,EDWARD J KASARSKIS, RG MCALLISTER ............................................................... 1140A comparison of the changes in suprathreshold apparent contrast in acute and simulated optic neuritisM ABRAHAMSSON, J SJOSTRAND....................................................................... 1147F-response behaviour in a control population s PEIOGLOU-HARMOUSSI, D HOWEL, PRW FAWCETT, DD BARWICK 1152F-responses: a study of frequency, shape and amplitude characteristics in healthy control subjectsSOTIRIA PEIOGLOU-HARMOUSSI, PETER RW FAWCETT, DENISE HOWELL, DAVID D BARWICK ..... ................. 1159

SHORT REPORTS

The neuroanatomy of vomiting in man: association of projectile vomiting with a solitary metastasis in the lateraltegmentum of the pons and the middle cerebellar peduncle PHILIP CH BAKER, JAMES L BERNAT .... ......... 1165Effect of naltrexone on senile dementia of the Alzheimer type BRADLEY T HYMAN, PAUL J ESLINGER, ANTONIO RDAMASIO .................................................................................... 1169A comparison of the frequency of major affective disorder in Huntington's disease and Alzheimer's diseaseRHS MINDHAM, CYNTHIA STEELE, M FOLSTEIN, JANE LUCAS ............................................... 1172Subacute spongiform encephalopathy (Creutzfeldt-Jakob disease) with amyloid angiopathy C KEOHANE,R PEATFIELD, LW DUCHEN ......................................................................... 1175Syndrome of the mesencephalic artery: report of a case with CT and necropsy findings M SETH HOCHMAN,JORGE J SOWERS, JOCELYN BRUCE-GREGORIOS ........... ............................................... 1179Polyneuritis cranialis associated with Borrelia burgdorferi E SCHMUTZHARD, G STANEK, P POHL .... ......... 1182

LETTERS

Plasma citrate in motor neuron disease STEINAR T VILMING ........................................... 1185Opsoclonus in hyperosmolar nonketotic coma SHOSAKU NODA, AKIRA TAKAO, HIROAKI ITOH, HIROTOSHI UMEZAKI 1186Successful treatment of migraine attacks with intravenous injection of aspirin SHOSAKU NODA, HIROAKI ITOH,HIROTOSHI UMEZAKI, YASUO FUKUDA .............. .................................................. 1187Chronic mucormycosis manifesting as hydrocephalus LATA S BICHILE, SHASHIKALA C ABHYANKAR, NK HASE 1187Impaired neurotransmitter amine metabolism in arginase deficiency K HYLAND, ISABEL SMITH, PT CLAYTON,JV LEONARD ..................................................................................... 1188MATTERS ARISING .................................................................................. 1190BOOK REVIEWS ................................................................................... 1191

No 12 DECEMBER 1985OCCASIONAL REVIEWTreatment of peripheral neuropathies MARK HALLETT, DEEPAK TANDON, ALFREDO BERARDELLI .... .......... 1193Ruptured intracranial aneurysms: the overall effect of treatment and the influence of patient selection and datapresentation on the reported outcome RS MAURICE-WILLIAMS, H MARSH ................................. 1208A potential application for the intracerebral injection of drugs entrapped within liposomes in the treatment ofhuman cerebral gliomas RONALD 0 MCKERAN, GARY FIRTH, SPENCER OLIVER, DAVID UTTLEY, SEAN O'LAORE ... 1213Magnetic resonance imaging in the diagnosis of spinal cord diseases F AICHNER, W POEWE, W ROGALSKY,K WALLNOFER, J WILLEIT, F GERSTENBRAND .......................................................... 1220Carotid blood flow measured by an ultrasonic volume flowmeter in carotid stenosis and patients withdementia SUMIO UEMATSU, MARSHAL F FOLSTEIN ..................................................... 1230Cognitive deficits in the Steele-Richardson-Olszewski syndrome (progressive supranuclear palsy) ER MAHER,EILEEN M SMITH, AJ LEES........................................................................... 1234Respiration and sleep in Parkinson's disease MCP APPS, PC SHEAFF, DA INGRAM, C KENNARD, DW EMPEY ..... 1240Acetylcholine receptor antibody as a diagnostic test for myasthenia gravis: results in 153 validated cases and 2967diagnostic assays A VINCENT, J NEWSOM-DAVIS.1246



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Neuromuscular function in limb girdle dystrophy AY BELANGER, AJ MCCOMAS ............................ 1253

An hereditary sensory and autonomic neuropathy transmitted as an X-linked recessive trait iv JESTICO, PA URRY,J EFPHIMIOU ...................................................................................... 1259

Laser injury of peripheral nerve: a model for focal endoneurial damage ROBERT R MYERS, HECTOR E JAMES, HENRYC POWELL ..................................................................................... 1265

Congenital hypomyelinating neuropathy YADOLLAH HARATI, IAN J BUTLER .............................. 1269

Dopamine agonists suppress visual-cortical reflex myoclonus JA OBESO, J ARTIEDA, T TUNON, MR LUQUIN,JM MARTINEZ LAGE............................................................................... 1277

Jaw, blink and corneal reflex latencies in multiple sclerosis EACM SANDERS, BW ONGERBOER DE VISSER,EC BARENDSWAARD, RJHM ARTS ................. .................................................... 1284

Lipoid proteinosis presenting with neuropsychiatric manifestations ROBIN A EMSLEY, LOUIS PASTER .... ..... 1290

SHORT REPORTS

A case of Gilles de la Tourette's syndrome with midbrain involvement JPWF LAKKE, JT WILMINK .... ....... 1293

Bethanechol decreases reaction time in senile dementia of the Alzheimer type P DAVOUS, Y LAMOUR ........ 1297

Unexpected improvement after prolonged posttraumatic vegetative state WFM ARTS, HR VAN DONGEN, J VAN

HOF-VAN DUIN, E LAMMENS ......................................................................... 1300

LETTERS

Neuroleptic malignant syndrome associated with metoclopramide MB ROBINSON, RP KENNETT, AE HARDING,NJ LEGG, B CLARKE............................................................................... 1304

Catamenial exacerbation of action myoclonus: successful treatment with acetazolamide MARK G GOETTING 1304

Enophthalmos and metastatic carcinoma of the breast PD THOMPSON, RJS WISE, BE KENDALL ..... .......... 1305

Pseudomonas osteitis causing cranial nerve palsies AHV SCHAPIRA, AN GALE ............................. 1306

Nutritional amblyopia in a patient with Crohn's disease ROBERT IANSEK, CHRISTOPHER J EDGE .... ......... 1307

Prolactin cell autoantibodies and Alzheimer's disease TA VAN DORP, Li ENDTZ, J TE VELDE, JPJ SLAETS, J REICHGELT 1308

Muscle hypertrophy in chronic polymyositis K PRASAD, M BEHARI, MC MAHESHWARI ..... ................. 1309

MATTERS ARISING ................................................................................. 1310

NOTICE ......................................................................................... 1310

BOOK REVIEWS ................................................................................... 1311

INDEX ...................................................................................... 1313



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