Journal Hospital Capacity Planning

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  • Faculty of Business and Economics

    A multilevel integrative approach to hospital case mix and capacity planningGuoxuan Ma & Erik Demeulemeester

    DEPARTMENT OF DECISION SCIENCES AND INFORMATION MANAGEMENT (KBI)

  • KBI 1201

  • A multilevel integrative approach to hospital case mix and capacity planning

    Guoxuan Ma & Erik Demeulemeester*

    Katholieke Universiteit Leuven, Faculty of Business and

    Economics Department of Decision Sciences and Information

    Management Naamsestraat 69, B-3000 Leuven, Belgium

    Tel: +32-16-32.69.72

    Fax: +32-16-32.66.24

    [email protected]

    [email protected]

    * Corresponding author

    1

  • A multilevel integrative approach to hospital case mix and capacity planning

    Abstract:

    Hospital case mix and capacity planning involves the decision making both on patient volumes

    that can be taken care of at a hospital and on resource requirements and capacity management. In

    this research, to advance both the hospital resource efficiency and the health care service level, a

    multilevel integrative approach to the planning problem is proposed on the basis of mathematical

    programming modeling and simulation analysis. It consists of three stages, namely the case mix

    planning phase, the master surgery scheduling phase and the operational performance evaluation

    phase. At the case mix planning phase, a hospital is assumed to choose the optimal patient mix

    and volume that can bring the maximum overall financial contribution under the given resource

    capacity. Then, in order to improve the patient service level potentially, the total expected bed

    shortage due to the variable length of stay of patients is minimized through reallocating the bed

    capacity and building balanced master surgery schedules at the master surgery scheduling phase.

    After that, the performance evaluation is carried out at the operational stage through simulation

    analysis, and a few effective operational policies are suggested and analyzed to enhance the

    trade-offs between resource efficiency and service level. The three stages are interacting and are

    combined in an iterative way to make sound decisions both on the patient case mix and on the

    resource allocation.

    Keywords: health care, case mix and capacity planning, master surgery schedule, multilevel,

    resource efficiency, service level

    2

  • 1 Introduction

    In Belgium, the total health expenditures increase year after year and may expand potentially in

    the future. Actually, 15.38 billion Euro was spent in the health care sector in 2003, whereas this

    number was increased to 20.70 billion Euro in 2008 (RIZIV [1]). This represents an increase from

    9.6% of the gross domestic product in 2003 to 10.2% in 2008 (OECD [2]). On the one hand, this

    increment attributes to an aging population growth combined with new and more expensive

    treatments, but on the other hand it is also the result of the incapability of the hospital to handle

    the decision making at strategic, tactical and operational levels in an integrative way, resulting in

    inefficiencies of the hospital operations.

    Moreover, an inefficient hospital management will not only bring huge economic pressures to a

    hospital, but also result in the waste of precious resources and the inefficiency of the patient flow,

    as exemplified by long waiting lists, surgery cancellations or patient misplacements, which will

    directly impact the health care service level. Particularly, under the limited resource capacity in a

    given hospital, the inevitable variability within health systems, both from the hospital supply side

    (e.g., a machine breakdown, surgeons called away for emergency) and from the patient demand

    side (e.g., random patient arrivals, stochastic surgery durations), will undoubtedly further add to

    this inefficiency. Therefore, it becomes important for the health care sector to improve both the

    hospital resource efficiency and the health service level, and it becomes increasingly necessary

    for hospitals to investigate the production management problem in a systematic way.

    Firstly, in order to mitigate the increasing economic pressures, hospitals are prone to advance the

    financial contribution of their resources through an efficient capacity allocation and management.

    Naturally, it is expected that the available resource capacity may match the stochastic patient

    demand as perfectly as possible and the utilizations of multifold resources (i.e., hospital beds,

    3

  • operating rooms (ORs), nursing staff, etc.) may be coordinated as best as possible. Nevertheless,

    due to the scarcity of resources and the variability (e.g., the random patient arrivals, the variable

    length of stays (LOSs), etc.) within the patient flow, the capacity management problem seems to

    be quite complicated. But it is fortunate that, as pointed out by Michael Carter [3], these complex

    problems within health care systems could benefit from operational research methods, such as

    mathematical programming, discrete-event simulation, and so on.

    To implement target patient throughputs, Vissers [4] combines hospital production management

    and resource capacity planning together, and proposes a formalized method to allot the resource

    capacity within a whole hospital. Two mathematical models are built to calculate the resource

    requirements of each specialty. One supports long-term decisions about the resources required to

    match the future patient demand, and another supports decision making at the medium-term level

    for balancing the resource requirements of various types. Similarly, for the financial purpose, it is

    also beneficial for a hospital to integrate the production management and the capacity planning.

    Here, a hospital pursues to choose the patient mix and volume of different pathology types that

    can bring maximum profits and to determine the corresponding hospital-wide resource allocation.

    The mix and volume of different types of patients are referred to as the patient case mix [5] in this

    context, and the production management problem is referred to as the hospital case mix and

    capacity planning problem. Clearly, this hospital planning problem involves the decision making

    both on patient volumes and on resource requirements and allocation, and thus concerns both the

    patient volumes planning and control level and the resources planning and control level within

    the health care production control framework of Vissers et al. [6].

    Hospitals are classified into two categories: constrained profit satisfiers and profit maximizers

    [7], according to the different profit targets of health care providers. Constrained profit satisfiers

    4

  • are motivated by professional interests rather than economic returns. A profit satisfier hospital

    seeks for the preferred case mix pattern or other preset objectives on condition that it can manage

    to break even without violating the capacity constraints [8]. On the other hand, profit maximizer

    hospitals are assumed to be positioned in a competitive business environment and thus they are

    willing to choose the patient cases that will bring the maximum rewards (e.g., [9-11]). In these

    papers, the mathematical programming models (i.e., linear programming, integer programming,

    goal programming) are deployed to solve the intended patient case mix. Moreover, in previous

    research [11], an efficient solution method for huge integer programs, branch-and-price [12], is

    presented and applied to solve the case mix problem optimally. In addition, to reflect and contain

    the variability in the system (e.g., the variable LOS of patients) into the planning model, both

    Utley et al. [13] and Adan et al. [14] successfully translate the stochastic resource requirements

    into the mathematical modeling by replacing the expected LOS with its probability distribution,

    and receive a better result from these stochastic models when solving the patient case mix and/or

    the allocation of resources in real configurations.

    Secondly, as mentioned above, the inevitable variability in the health care system will not only

    influence the resource utilization [15-17], but also affect the service level of health care delivery

    [18-21]. Specifically, both the unpredictable patient demand (e.g., emergency admissions [15])

    and the variable length of stay of patients (e.g., [13, 14, 16]) have a considerable impact on the

    fluctuation of bed capacity requirements. Moreover, Green [17] points out that the bed capacity

    planning should not be based on the target occupancy level only, but be connected with measures

    of patient delays, such as patient refused admission rate [18], patient waiting time [19], surgery

    cancellation [20], and patient misplacement [21]. To assess the operational performance and to

    examine the health care service level, a queueing model is adopted in [18] and simulation models

    5

  • are applied in [19-21]. In addition, besides the variability, changes in a cyclic master surgery

    schedule itself also affect bed consumptions. For instance, Belin et al. [22] present a software

    system that visualizes the impact of the master surgery schedule on the demand for other various

    resources throughout the rest of the hospital.

    Apparently, the balanced use of various resources will not only increase the resource efficiency

    but advance the patient service level. Hence, it is significant to harmonize the utilization of, e.g.,

    operating rooms and beds, in order to acquire an efficient patient flow in the health care system.

    Belin and Demeulemeester [23] take into account the resulting daily bed occupancy levels when

    building cyclic master surgery schedules. The variable LOS of patients will bring fluctuations in

    the bed capacity requirement and deviations of the real bed demand from the assigned capacity,

    which causes the bed shortage phenomenon. Then, the bed shortage will lower the patient service

    level, since it either makes the scheduled surgery to be cancelled [20] or it makes the operated

    patient to be misplaced [21]. Hence, it is meaningful to seek for a balanced cyclic master surgery

    schedule through minimizing the total expected bed shortages [23]. Besides, van Oostrum et al.

    [24] also incorporate maximizing OR utilizations and leveling bed requirements together when

    scheduling the surgery procedures into operating rooms.

    In addition, there also exist a number of articles [25-27] applying an integrative approach to the

    hospital planning problems. Bretthauer and Ct [25] develop an optimization/queueing network

    model to determine resource requirements, which minimizes the capacity costs while controlling

    the customer service by enforcing a set of performance constraints. The queueing network model

    allows to involve the stochastic property of health care systems and to estimate the service levels

    within an optimization framework. Butler et al. [26] propose a two-phase model-based approach

    to the hospital layout problem. A quadratic integer goal programming model is built to determine

    6

  • a hospital configuration and the allocation of beds to health services in the first phase. Then, the

    detailed ramification of the suggested layout is assessed in the second phase through a simulation

    model. Oddoye et al. [27] also combine simulation analysis with goal programming modeling for

    the healthcare planning in order to achieve an optimal clinical workflow.

    In this research, to overcome the increasing economic pressures on hospitals and the inefficiency

    in patient flows, the case mix and capacity planning problem is studied comprehensively, which

    on the one hand maximizes the financial contribution of the given resources at a hospital, and on

    the other hand improves the health care service level under the variability condition. To achieve

    the efficient trade-offs between resource efficiency and service level, an integrative three-phased

    solution approach is proposed, in which the first phase aims at maximizing the overall profits,

    the second phase is focused on reducing the total expected bed shortages, and the third phase

    works on assessing the operations performance and on analyzing the suggested effective policies.

    Each phase has its own emphasis and merits, and their solutions complement each other and

    complete the sound decision making for the hospital planning problem.

    The remainder of this paper is structured as follows. Section 2 describes the hospital case mix

    and capacity planning problem briefly and addresses some concerned matters being valuable to

    the planning process. Section 3 specifies the proposed solution methodology for the planning

    problem, which is a multilevel model-based integrative approach on the basis of operational

    research methods, i.e., mathematical (integer linear) programming and discrete-event simulation.

    The methodology framework is formulated and explained in detail, and each phase is elaborated

    respectively. Afterwards, an example is applied to demonstrate the efficiency and the importance

    of the designed integrative method in Section 4. Finally, in Section 5 we draw the conclusions of

    this paper and mention some ideas for further developments.

    7

  • 2 Problem description

    As discussed above, the hospital case mix and capacity planning problem concerns the decision

    making both at the patient volumes planning and control level and at the resources planning and

    control level of the hierarchical framework for production control of hospitals [6]. Both levels

    consider an entire hospital as the main unit of analysis. The patient volumes planning and control

    level with a planning horizon of 1 to 2 years concerns the long-term decision making on patient

    flows and resources. Decisions regarding patient flows consist of the annual number of patients

    that can be treated per pathology group, namely the patient case mix, while decisions regarding

    resources consist of the capacity requirement of each specialty within the hospital. The objective

    is to match patient demands and supplied resources as best as possible. The resources planning

    and control level with a planning horizon of 3 months to 1 year concerns the decision making at

    the medium-term level, which consists of the time-phased resource allocation and the capacity

    coordination requirement. The objective is to maximally coordinate the utilization of multifold

    resources (e.g., operating rooms and beds) within the whole hospital. Ignoring this coordination

    may result in capacity losses, i.e., a poor performance in resource utilization. Hence, integrating

    the decision making at both levels is beneficial to produce an efficient patient flow and thus to

    advance the hospitals production efficiency.

    A hospital might be considered as a production system, in which the scarce resources are used to

    support the patient flow. Then, the demand side of a hospital consists of the many patients with

    different pathologies that enter the hospital according to their own time pattern, while the supply

    side consists on the one hand of the available personnel (e.g., surgeons, nursing staff) and on the

    other hand of the material resources (e.g., operating rooms, beds). The objective of a hospital is

    to match its supply and demand side in the best possible way, resulting in a quick, reliable and

    8

  • efficient patient service. However, the uncertainty existing in the health care system will play a

    destructive role on the efficiency of the health service delivery.

    In this study, a hospital is assumed to be a profit maximizer. From an organizational perspective,

    the hospital is assumed to possess a fixed number of different departments and a common

    surgical center. Each department has its own surgeon groups and its own ward with a certain

    number of beds accommodating the recovery of its patients. Each surgeon group is engaged in

    one specialized medical field covering a few similar pathologies, and usually contains a certain

    number of equally qualified surgeons, who are inter-replaceable when performing surgery on

    their patients. The common surgical center is assumed to comprise a certain number of identical

    operating rooms (ORs), which are shared by all surgeon groups for performing surgeries. While

    hospital beds are allocated to each ward in a fixed way, operating rooms are assigned to surgeon

    groups in a time-phased manner. Clearly, operating rooms are the time-shared leading resources,

    while beds are the following resources. In the context of this research, emergency patients are

    assumed to be taken care of by the emergency department with the reserved capacity, and thus

    are left out of the planning process. The involved elective inpatients are classified into different

    patient groups according to an iso-process grouping procedure [6], and each patient group is

    characterized by a series of observed parameters: i.e., the average reward of the treatment, the

    specialized surgeon group, the expected surgery duration and the expected LOS with their

    probability distributions. Clearly, one surgeon group may perform surgeries on several different

    patient groups, but one patient group can only be treated by one surgeon group.

    Figure 1 shows an example of the general hospital configuration, which clearly illustrates the

    relationship amongst wards, surgeon groups (S1 to S4) and patient groups (P1 to P9): e.g.,

    surgeon group S1 takes care of patient groups P1 and P2, which will normally get recovery beds

    9

  • in Ward 1, and all patient groups P6 to P9, which are taken care of by surgeon groups S3 and S4

    respectively, will normally end up in Ward 2.

    Figure 1: Hospital configuration (S: surgeon group, P: patient group)

    Generally speaking, given the predictions of the number of patients that will enter a hospital with

    a certain pathology, given the expected financial reward, the expected operating time and the

    expected LOS per patient group and given the knowledge to which surgeon group and to which

    ward a patient with a certain pathology will be assigned, the basic hospital case mix and capacity

    planning problem consists of determining how operating rooms are assigned to surgeon groups,

    how many beds are allocated to each ward and how many patients from each pathology group

    can be taken care of at the hospital over the course of one year in view of maximizing the overall

    contribution. As a result, an optimal case mix pattern generating the maximum profits is sought,

    accompanied by a corresponding resource allocation scheme.

    In previous research [11], the basic planning model generates the optimal case mix decision

    within a deterministic system, through matching the given resource capacity and various patient

    demands optimally from the perspective of resource efficiency. However, the uncertainty in the

    health care system, both from the arrival process and from the treatment process, not only upsets

    the resource utilization [14, 15, 16], but further impacts the patient service level [18, 19, 20, 21].

  • 10

  • Therefore, in order to make sound decisions on case mix and resource allocation, it becomes of

    necessity to incorporate the variability into the capacity planning process.

    Additionally, there are some other reasons influencing the medium-term decision on the resource

    allocation. First, according to our contacts with a number of well-reputed Belgian hospitals, we

    know that typically every six months (sometimes a year) a reallocation of capacity is performed

    based on proven capacity use in the previous six months (or a year). As such, the allocation of

    resources is based on historical rights rather than on real data on the demand for and use of

    resources. Apparently, the current practice fails to provide a sound decision on the allocation of

    resources if a number of changes have taken place in the hospital during the period of six months,

    such as, the treatment of a certain pathology is changed (e.g., a different surgery procedure for a

    hip replacement results in a reduction of the average LOS from 9 to 7 days). The second possible

    reason considered is the time varying demand over the months, e.g., the seasonality in epidemics.

    Clearly, the patient arrivals in one department may vary periodically, while another department

    may have a countercyclical patient demand pattern. Then, for the hospital efficiency as a whole, it

    is helpful to allow borrowing beds from an idle department to a busy one or to set swing beds

    that can be shared by clinical units that have countercyclical demand patterns [17].

    3 The multilevel integrative approach

    In this section, a multilevel model-based integrative approach is built to solve the hospital case

    mix and capacity planning problem. The solution methodology is based on operational research

    methods, such as mathematical programming and discrete-event simulation. It consists of three

    phases, each of which has its own emphasis and function and has a corresponding mathematical

    modeling. In the following, the methodology framework is formulated and explained clearly, and

    then each phase is elaborated in more detail.

    11

  • 3.1 Methodology framework

    The studied case mix and capacity planning problem has two distinct objectives: (1) maximizing

    the hospital resource efficiency and (2) improving the patient service level. Since each target has

    its own perspective and characteristics, it seems to be necessary to introduce a combined solution

    approach to achieve both objectives. Actually, our proposed solution approach comprises both a

    deterministic analysis and a stochastic analysis. The deterministic analysis allows to determine

    the optimal patient mix to be served, but it is unable to take the impact of variability into account.

    The stochastic analysis may reflect the influence of variability and explain the trade-offs between

    resource efficiency and service level for a given case mix, but does not give an optimal case mix.

    Clearly, both analyses are complementary in nature, and both are indispensable for studying the

    planning problem at hand in order to fulfill the two objectives.

    Specifically, the proposed solution methodology includes three stages: i.e., the case mix planning

    phase, the master surgery scheduling (MSS) phase and the operational performance evaluation

    phase. The case mix planning phase involves the long-term decision making on patient volumes

    and capacity requirements of each specialty within a deterministic system, while the MSS phase

    considers the medium-term decision on resource allocation, i.e., a cyclic master surgery schedule,

    and takes into account the variability and its effect on resource utilizations, e.g., the expected bed

    occupancy of each ward. The performance evaluation phase is applied to assess and analyze the

    operational performance of a given case mix and capacity decision within a stochastic system.

    Figure 2 displays the basic methodology framework. Clearly, there exists a loop among the three

    stages. Firstly, at the case mix planning phase, the optimal case mix pattern is sought, as well as

    the accompanying capacity allocation scheme is produced. Then, the solved case mix decision is

    communicated to the MSS phase, in which a balanced master surgery schedule is generated

    12

  • with an improved resource utilization. Afterwards, the obtained case mix and capacity decision is

    translated into the operational performance phase, in which the performance evaluation is carried

    out in order to advance the health service level and to give valuable feedback to the upper stages.

    Thus, the three stages are interacting and are combined in an iterative way to form a multilevel

    integrative approach to the hospital planning problem with multiple objectives.

    Case mix planning phase

    Aim: maximizing the resource efficiency

    Decision: case mix & capacity allocation

    Method: integer linear programming Interaction & feedbackCapacity:

    Adapting the bed capacityMaster surgery scheduling phase

    Aim: improving the resource utilization

    Decision: cyclic master surgery scheduleMethod: mixed integer programming

    Variability:Altering the probability

    Performance evaluation phase distribution of the LOS, etc.

    Aim: advancing the health service level

    Decision: effective operations policies

    Method: discrete-event simulation

    Figure 2: Methodology framework

    At the case mix planning phase, the hospital is considered as a deterministic system, in which the

    patient treatment is following a standard care process for each patient group. The objective is to

    maximize the resource efficiency, so the hospital aims at choosing the optimal patient case mix

    that will bring the maximum overall financial contribution under the given resource capacity. In

    order to achieve this objective, a mathematical (integer linear) programming model is built to

    determine the optimal case mix pattern as well as the corresponding capacity allocation scheme.

  • 13

  • Then, the solved optimal case mix pattern is communicated as a constraint to the lower levels to

    make further decisions (e.g., the balanced master surgery schedule).

    At the MSS phase, the variable resource requirement of each patient group is taken into account,

    which may impact the resource utilization, for example, the varied surgery duration may result in

    overtime in operating rooms, the variable LOS may result in bed shortages in a ward, and so on.

    Clearly, the variable LOS will impact the daily bed requirement of each ward, i.e., the expected

    bed demand may exceed the allocated bed capacity, which thus causes bed shortages. As a result,

    the bed shortage will force the scheduled surgeries to be cancelled or the operated patients to be

    misplaced, which lowers the patient service level. Hence, the objective at this level is to improve

    the resource utilization, i.e., minimizing the total expected bed shortage (TEBS) through leveling

    the daily bed occupancy of each ward. For this purpose, a mixed integer programming model is

    proposed to build a balanced master surgery schedule with leveled resulting bed occupancy at

    each ward. Then, the balanced master surgery schedule together with the optimal case mix will

    be evaluated under the variability condition at the operational level.

    At the performance evaluation phase, the variability is introduced explicitly, such as the random

    patient arrivals and the stochastic resource requirements of each patient. For the purpose of the

    performance evaluation, a discrete-event simulation model is developed. The simulation analysis

    is applied to evaluate the operational performance of the provided case mix and capacity decision,

    and to analyze the suggested operations policies in order to improve the health care service level.

    The effective operations policies include adapting the bed capacity appropriately and altering the

    probability distribution of the LOS, both of which are helpful to advance the patient service level.

    Finally, the valuable effects of the operations policies are fed back to the upper stages to enhance

    the trade-offs between resource efficiency and service level.

    14

  • 3.2 Case mix planning

    At this level, a hospital is considered as a deterministic production system, in which each patient

    group represents a standard product type with a well-defined resource requirement structure. The

    patient treatment is following a standard procedure for each patient group. Then, patients within

    a same group will occupy the same constellation of resources, such as equal operating room time

    and equal bed days, and contribute the same reward to the hospital.

    The determination of how many patients from each pathology group can be treated at a hospital

    over the course of one year is called the case mix planning problem. Aiming at maximizing the

    resource efficiency, the case mix planning problem will determine an optimal case mix pattern

    that can bring the maximum overall financial contribution, accompanied by a capacity allocation

    scheme over the whole hospital. To allocate the time-shared operating rooms to various surgeon

    groups, an OR block is defined as the smallest time unit for which an operating room can be

    assigned to a surgeon group to perform surgeries exclusively. The block length is usually set as

    eight hours, but this block length can easily be changed into other units (e.g., four hours). Here, it

    should be mentioned that the special surgery cases with a planned duration that is longer than the

    block length are excluded from this discussion. In addition, the case mix pattern is determined

    periodically with a cycle length of one week or a multiple of weeks.

    In order to model the case mix planning problem mathematically, the required notation is defined

    as follows and remains valid for the rest of the paper. The needed sets and indices are:

    set of wards with index ;

    set of surgeon groups with index ;

    set of patient groups with index ;

    set of days in a cycle with index ;

    15

  • set of active days in a cycle with index ;

    subset of surgeon groups whose patients are moved in ward after surgery is performed;

    subset of patient groups of which the patients occupy the beds of ward ;

    subset of patient groups of which the patients are operated on by surgeon group ;

    subset of active days for which it applies that patients of group still stay in hospital on

    day if they underwent surgery on that day. (Remark: for the patient group with a mean

    LOS being longer than the cycle length, an active day may be counted multiple times.)

    The coefficients and the right hand side values are:

    the profit generated by treating a patient of patient group ;

    the surgery duration time of operating on a patient of patient group ;

    the lower bound on the number of patients of group that can be treated per cycle;

    the upper bound on the number of patients of group that can be treated per cycle;

    the total number of available beds (assumed to be the existing bed capacity);

    the total number of OR blocks per day (assumed to be the daily block capacity);

    the operating room block length (assumed to be 480 minutes).

    In addition, the decision variables include:

    the number of patients of patient group that receive surgery on day ;

    the number of beds assigned to ward ;

    the number of OR blocks assigned to surgeon group on day .

    Then, the hospital case mix planning problem is formulated as an integer linear programming

    (ILP) model as below:

    16

  • The objective function (1) maximizes the total financial contribution. Constraint (2) indicates the

    allocation of bed capacity. Constraint set (3) denotes that the daily bed occupancy of each ward

    cannot exceed its allocated capacity. Constraint set (4) reflects the time-phased allocation of OR

    blocks. Constraint set (5) indicates that the total surgery time for each surgeon group on an active

    day cannot exceed the assigned block length. Constraints (6) denote the admission volume bound

    of each patient group and constraints (7) reflect the integer property of the decision variables.

    Generally, the above formulation results in a huge integer program even for a hospital of regular

    size. For instance, for a hospital with 25 departments, if each department possesses three surgeon

    groups, each of which treats three patient groups on average, and if the cycle length is assumed

    to be one week, the ILP modeling will contain 1525 integer variables. Basically, no commercial

    ILP software (e.g., ILOG CPLEX) can solve an integer problem of this dimension effectively. In

    previous research [11], numerical experiments have shown that CPLEX fails to give an optimal

    or a feasible solution efficiently even for a hospital with five departments, but it is fortunate that

    an efficient branch-and-price approach has been developed to cope with this huge ILP model.

    17

  • 3.3 Master surgery scheduling

    At the case mix planning phase, besides an optimal case mix pattern, the corresponding resource

    capacity requirement of each specialty is also determined. However, the capacity allocation plan

    is a rough decision, since on the one hand it does not consider the variability and its impact on

    resource utilization and on the other hand it is a long-term decision, which neglects the medium-

    term factors, such as the seasonality. As mentioned before, the variability will affect the resource

    utilization, and further impact the patient service. Therefore, it becomes important to incorporate

    the variability at the master surgery scheduling phase to determine the refined resource allocation

    at the medium-term level (e.g., the balanced cyclic master surgery schedule) from the perspective

    of the improved resource utilization.

    As discussed above, both the cyclic master surgery schedule and the variable LOS of patients

    influence the daily bed occupancy of each ward. The variable LOS may introduce bed shortages,

    which thus lowers the patient service level. Hence, it is meaningful to reduce the total expected

    bed shortage as best as possible. In order to minimize the total expected bed shortage at the MSS

    phase, one attempts to take the variability of the LOS into account and to build a balanced master

    surgery schedule with a leveled resulting bed occupancy at each ward. At this phase, the concept

    of the expected bed shortage (EBS) is introduced to reflect the daily bed occupancy at each ward,

    and the probability distribution of the LOS of each patient group is applied to calculate the EBSs.

    Basically, the rough capacity decision at the case mix planning level may result in an unbalanced

    bed distribution (i.e., the possible spare beds are assigned to a few wards, which may cause a bed

    redundancy in some wards and a bed deficit in others) and the uneven peaks and troughs of bed

    occupancy at each ward. Then, a balanced master surgery schedule is built through reallocating

    the bed capacity and reassigning the OR blocks to level the bed occupancy of each ward.

    18

  • In order to build a balanced master surgery schedule with a leveled resulting bed occupancy, a

    mathematical (mixed integer) programming model that aims at minimizing the total expected bed

    shortage (TEBS) is proposed as below:

    In this model, represents the total expected bed shortage of ward , while denotes

    the patient throughput of pathology group , which is received from the case mix planning level.

    This model seems to be similar with the one derived in the literature [23], but there are two main

    differences. First, the basic driving force to construct a master surgery schedule in this model is

    the case mix variable instead of the block assignment variable . Thereby, in this case each

    surgeon group can perform a few different surgery types in one assigned OR block. Second, only

    one ward is considered in [23], whereas our proposed modeling involves multiple wards. Hence,

    this model is an improved extension to the one presented in [23]. However, similarly as pointed

    out in [23], the total expected bed shortage of each ward cannot easily be expressed in

    terms of the decision variables due to the complicated combinations of the stochastic

    variables of the bed occupancy volume, which makes the above model intractable.

    19

  • To be able to solve the MSS problem effectively, we present an efficient approximation to the

    objective function (8), instead of calculating the complicated directly. In the following, a simple

    version of the mixed integer programming (MIP) model is addressed to approximate the

    minimization of the total expected bed shortage over all wards. Moreover, in order to generate

    the master surgery schedule with more balanced bed occupancy levels, the OR blocks are relaxed

    to be more flexible (e.g., one 8-hour OR session is divided into two 4-hour sessions, or the block

    length is changed from 8 hours to 4 or 6 hours, but the total capacity of each OR-day is limited to

    at most 10 hours, etc). Then, a linear approximation MIP model is given below:

    20

  • The above model is applied to produce a balanced cyclic master surgery schedule with a leveled

    resulting bed occupancy. Here, constraints (11) and (12) respectively express the mean value and

    the variance of the bed requirement of ward on day , in which denotes the probability

    that a patient of group is still an inpatient days after being operated on. In constraints (13), the

    negative deviation indicates the bed deficit and the positive deviation represents the bed

    surplus of ward on day , while denotes the maximum daily spare bed volume of ward .

    Constraints (14) define the largest variance of the daily bed occupancy of each ward. In addition,

    constraints (15 - 16) are about the OR blocks, which are the variants of constraints (4) and (5)

    except that each operating room is considered individually and the blocks are differentiated into

    distinct lengths. denotes the set of rooms with an index , and denotes the set of block types

    with an index and a specific block length . indicates the operating capacity

    of room on day , and the binary decision variable implies whether the surgeon group

    obtains a block of type in room on day . Constraints (15) ensure that for each OR-day the

    assigned surgery blocks cannot exceed its capacity, while constraints (16) guarantee that every

    surgeon group acquires enough OR blocks to perform its surgeries. The objective function (10)

    contains three weighted parts for each ward: i.e., the total bed deficit , the maximum

    daily spare bed volume and the maximal variance of the bed occupancy .

    Clearly, the MSS approach implements refining the resource capacity allocation. In addition, the

    MSS model is also applied to adjust the cyclic master surgery schedule at the medium-term level,

    according to the expected seasonal patient admission in place of the average target throughput of

    each patient group. The adaptation of the target patient throughput is helpful to reduce the patient

    waiting list. However, the revision should satisfy the condition that the given resource capacity is

    sufficient for each specialty in the deterministic environment.

    21

  • 3.4 Operational performance evaluation

    At the performance evaluation level, a discrete-event simulation model is developed to reflect the

    dynamic property of the health care system. Then, the variability within the health care system,

    either from the patient arrival process or from the patient treatment process, might be included

    explicitly. The simulation model is applied to evaluate the operational performance of the case

    mix and capacity decision that is obtained at the upper stages under the uncertainty condition.

    Moreover, in order to advance the trade-offs between resource efficiency and patient service, two

    effective operational policies are introduced, which are respectively adapting the bed capacity

    appropriately and altering the distribution of the variable LOS. The policies are analyzed through

    simulation experiments and the acquired valuable effects are fed back to the upper stages.

    The discrete-event simulation model is built through using the user-friendly simulation software

    Arena version 11.0 [28]. It is elaborated in the previous research [21] and applied in this research

    to implement the performance evaluation. More specifically, a hospital is modeled as a stochastic

    production system, in which the random patient arrivals and the stochastic resource requirements

    of each patient are achieved by adopting probability distribution functions. Patient arrivals are

    created randomly and enter into each department. According to their pathology type, patients are

    classified into different groups and are put on the corresponding waiting lists. The master surgery

    schedule that is solved at the MSS stage determines on each day how many and which patients of

    every (first in first out) waiting queue are admitted and go into the surgical center to be operated

    on by the proper surgeon groups. Afterwards, patients will move to a proper ward to get recovery.

    If there exist bed shortages in the proper ward, the operated patient will be misplaced in a second

    suitable ward to recover temporarily. However, once a free bed is available in the proper ward,

    the misplaced patient will be transferred back from the wrong ward to the correct one. The LOS

    22

  • of each patient follows a certain probability distribution. When patients get recovered, they will

    leave the hospital in the end. Thereby, a simulation modeling of a hospital is portrayed from the

    perspective of the patient flow.

    Ma and Demeulemeester [21] present a simulation modeling of a hospital with two departments.

    From the unit perspective, each department has its own patient arrival generators, which produce

    the patient arrivals of nine different pathology types randomly, as well as its corresponding three

    surgeon groups. Patients will wait for the admission and the treatment on their respective waiting

    lists. The surgical center has two operating rooms, which are shared and used by all six surgeon

    groups to perform surgeries on the total 18 patient groups, and the time-phased allocation of ORs

    is based on the obtained master surgery schedule. In addition, each department has an associated

    ward with a fixed number of beds to accommodate its patients for recovery. The number of beds

    at each ward is dependent on the planned resource allocation scheme. Besides, there exist a few

    temporary beds in the ward area, which will be used when no free bed is available at both wards.

    Clearly, the built simulation model by Arena is easily extendible and adaptable, so it is feasible to

    be applied in this research to implement the performance evaluation.

    In order to be able to conduct the simulation experiments, the built simulation model needs to be

    concretized. The required data, such as the patient arrival rate of each pathology type, the cyclic

    master surgery schedule and the bed capacity allocation to each ward, as well as the expected

    surgery duration and the probability distribution of the variable LOS of each patient group, need

    to be specified in the simulation model. In addition, as the solved case mix and capacity decision

    plan is effective for six months to one year, the replication length is set as 365 days, in which the

    warm-up period is fixed as 60 days, and the number of replications is set as 50 to achieve reliable

    results in the simulation experiment.

    23

  • In order to guarantee the target patient throughput and thus the maximum financial contribution,

    the planned surgery will not be canceled when there exist bed shortages in the destined ward, but

    we adopt a policy that the operated patient will be misplaced in a second suitable ward to recover

    temporarily. Therefore, not the surgery cancellation but the patient misplacement is defined as

    the main performance indicator reflecting the patient service level, whereas the bed occupancy

    rate is another main performance indicator reflecting the resource utilization. The weekly volume

    of patient arrivals of every pathology is in accordance with the solved case mix pattern to ensure

    sufficient patient admissions. In addition, different from the variable LOS, the surgery length of

    each patient is assumed to be deterministic in the simulation model and is set as the mean value

    of its corresponding patient group for two reasons. First, the variable surgery duration does not

    affect the planned patient admission and the resulting bed occupancy, but only incurs the under-

    or over-utilization of operating rooms. Second, the ORs overtime to some extent is common and

    allowed in most Belgian hospitals. Hence, the variable surgery duration is not considered and the

    ORs utilization is not involved in this research.

    The first objective of the performance evaluation phase is to assess and compare the operational

    performance of the produced various optimal case mix and capacity decisions through simulation

    experiments. Moreover, to advance the patient service level, two effective operational polices are

    proposed in this phase, which are analyzed through simulation experiments. Then, the obtained

    valuable information is fed back to the upper stages to further affect the case mix and capacity

    decision and to further influence the operational performance. The iteration is helpful to enhance

    the trade-offs between resource efficiency and service level, which is the second objective of this

    phase. The suggested two policies are respectively proposed from the perspective of capacity and

    of variability.

    24

  • The first efficient policy is to adapt the bed capacity appropriately. Because of the seasonality of

    patient arrivals, the bed requirement in some departments may be changed seasonally. That is, for

    one department there may exist a few spare beds at its ward during the low season, while the bed

    deficit may happen in a high season. However, for another department with countercyclical

    patient arrivals, there may appear a complementary bed requirement pattern. Then, for these two

    departments, if it is allowed to borrow/lend the spare beds from an idle department to a busy one

    temporarily, it will not only improve the bed utilization but also reduce the patient misplacement.

    If the simulation analysis shows that there exist bed shortages as a whole in the hospital in a busy

    period, we cope with this situation by staffing the stand-by beds during peak times or setting the

    swing beds shared by the departments with countercyclical demand patterns at the operational

    level. Furthermore, the bed deficit/surplus status will be fed back to the tactical level to adapt the

    bed capacity appropriately, i.e., expanding or reducing the total bed capacity.

    The second policy is to alter the probability distribution of the variable LOS properly. According

    to previous research [29], the patient delay and the bed utilization are tightly related with the

    variability within the healthcare system, which inspires us to examine the effect of the variability

    on the operational performance in this context. As mentioned before, a modified treatment of a

    pathology may cause the variable LOS to be changed, for example, the mean LOS is decreased

    and its probability distribution is varied as well. Undoubtedly, shortening the mean LOS of some

    pathologies will reduce both the bed occupancy and the patient misplacement as a whole, but the

    comparison seems to be unfair. Hence, we adopt a policy of changing the probability distribution

    but keeping the mean value of the variable LOS, which is called curtailing the distribution of the

    LOS (e.g., the distribution of a LOS with an interval between 3 and 11 days and an average of 7

    days is changed to one with an interval between 5 and 9 days and an average of 7 days). The

    25

  • policy of curtailing the distribution of the LOS not only influences the operational performance

    but also affects the decision of the cyclic master surgery schedule at the MSS phase. Besides, the

    shortened average LOS will also affect the case mix and capacity planning. Therefore, adjusting

    the variable LOS of patients can be fed back to the upper stages to further influence the case mix

    and capacity decision.

    4 An application

    In this section, a small example is applied to demonstrate the efficiency and the effectiveness of

    the built integrated solution methodology to the hospital case mix and capacity planning problem.

    To implement the illustration, we built a small-sized simulated hospital following the general

    organizational structure and the basic operating principle of most Belgian hospitals. So, the small

    numerical example is representative and can easily be extended and adapted to the real situation.

    In the solution process, the case mix planning model is solved optimally by using the developed

    branch-and-price algorithm, and the MSS model is solved with the commercial ILP solver ILOG

    CPLEX. Then, the created discrete-event simulation model by Arena is launched to perform the

    simulation analysis, and two groups of simulation experiments are conducted to interpret the two

    proposed operational policies.

    The fictitious hospital is assumed to have two departments (Dept. A and Dept. B) and a common

    surgical center with two time-shared operating rooms. Each department has three surgeon groups

    and each surgeon group can perform surgeries for three patient groups. Two operating rooms are

    open for eight hours on each working day, which are assigned to the total six surgeon groups

    based on the obtained resource allocation scheme. In addition, the random patient arrival of each

    pathology follows a certain non-stationary Poisson process. The expected surgery length of each

    pathology type is generated randomly from a uniform distribution between one and four hours.

    26

  • The variable LOS of each patient group is described by a discrete probability distribution. For

    example, a variable LOS with an average of days has the probability distribution as follows:

    , , and .

    The first experiment is to test the policy of adapting the bed capacity appropriately. According to

    the result of numerical experiments for the given hospital, when the total bed capacity reaches 38

    beds, the overall financial contribution arrives at the maximum value in the deterministic phase.

    At that time, operating rooms become a bottleneck resource. A bed expansion cannot increase the

    total profits but will influence the operational performance of the hospital under uncertainty.

    Thus, we devise a simulation experiment to evaluate and to compare the operational performance

    of three different bed capacity cases (i.e., 38 beds, 40 beds and 41 beds). The simulation results

    are displayed and compared in Table 1, in which the Base scenario refers to the rough resource

    allocation scheme by solving the case mix model, while the +MSS scenario refers to the refined

    resource allocation by further solving the MSS model.

    Exp.1: Adapting the bed 38 beds 40 beds 41 beds

    capacity appropriately Base +MSS Base +MSS Base +MSS

    Patient As MBDs 60.04 30.68 31.38 6.08 17.42 5.42

    Misplacement Bs MBDs 54.02 34.74 9.40 10.72 4.12 2.72

    Bed Days AB in T 56.80 27.42 8.64 4.34 2.46 1.32

    (MBDs) Total 114.06 65.42 40.78 16.80 21.54 8.14

    0.8566 0.8576 0.8581 0.7987 0.7894 0.7973Bed Ward A

    Occupancy 10.2792 10.2912 10.2966 10.3831 10.2620 10.3652

    Rate & 0.9028 0.9058 0.8494 0.8767 0.8384 0.8464Number Ward B

    23.4739 23.5505 23.7827 23.6704 23.4764 23.6979

    Table 1: Comparison results of adapting the total bed capacity

    27

  • The main performance indicators are compared in Table 1, comprising the patient misplacement

    bed days (MBDs) and the average bed occupancy of each ward. Here, AB in T represents the

    total misplacement bed days of patient A (patients of Dept. A) and patient B (patients of Dept. B)

    on temporary beds, which are occupied as both wards have no free bed available. A(B)s MBDs

    consist of the misplacement bed days of patient A(B) both in ward B(A) and on temporary beds.

    Besides, Total reflects the total misplaced bed days of patients A and B. Clearly, for each case,

    the refined resource allocation scenario has much better operational performance than the rough

    resource allocation scenario on the whole, as both the AB in T and the total MBDs demonstrate

    a definite decrease in total. In the first and the third cases, both patient As MBDs and patient Bs

    MBDs have evident decreases, and the bed occupancy rate shows a little increment. However, in

    the second case, patient Bs MBDs have some increment in the +MSS scenario and the average

    bed occupancy rates at two wards have an inverse change. This is because a spare bed of Ward B

    is reallocated to Ward A in the refined resource allocation plan. On the other hand, the quite high

    bed occupancy rate (more than 85% at both wards) in the case of 38 beds implies the necessity of

    expanding the total bed capacity. Clearly, when the total bed capacity reaches 41 beds, the bed

    occupancy rates of both wards decrease to lower than the baseline of 85%. In general, as the bed

    capacity gets expansion, both the total patient misplacement and the average bed occupancy have

    evident improvements, which thus advances the trade-offs between the patient service level and

    the hospital resource efficiency.

    The second experiment is to examine the efficiency of curtailing the distribution of the variable

    LOSs. To reflect the possible treatment improvement for some certain pathologies, it is assumed

    that the long-tailed LOS of some patient groups can get effectively controlled, which refers to the

    second policy that we introduced. In our numerical experiments, a variable LOS with an average

    28

  • of days and the probability distribution of , , ,

    , and is changed to one with a distribution of

    , , and .

    Figure 3 exhibits the effect of curtailing the distribution of the variable LOSs via the simulation

    experiments. Here, the Base scenario denotes the rough resource allocation without considering

    the variability, the Balanced scenario refers to the refined resource allocation after taking into

    account the variability, the mixed B&C scenario relates the refined resource allocation with the

    curtailing information in the performance evaluation phase, while the Curtailed scenario refers

    to the updated resource allocation after feeding back the curtailing information to the MSS stage.

    Apparently, the average bed occupancy rates remain constant, since the required overall bed days

    are unchanged. However, the patient misplacement bed days show definite improvements when

    considering the variability in different levels, which clearly reveals that the higher the degree of

    variability, the worse the operational performance will be for the same utilization level.

    45

    40

    35

    30

    25

    20

    15

    10

    5

    0Base Balanced

    Total MBDs

    AB inT

    BedsA Occupancy

    BedsB Occupancy

    Average Occupancy

    Figure 3: The effect of curtailing the

    distribution of the variable LOSs 29

  • According to the above simulation results, it is clearly shown that the operational performance of

    the optimal case mix and capacity decision derived from the proposed methodology, such as the

    +MSS scenario or the Curtailed scenario, presents visible improvements compared to the base

    case scenario derived from a deterministic approach. Therefore, the proposed integrative solution

    methodology is demonstrated to be effective to enhance the efficient trade-offs between hospital

    efficiency and patient service.

    5 Conclusions and future research

    This paper presents a multilevel integrative solution approach to a hospital case mix and capacity

    planning problem on the basis of mathematical programming and simulation analysis. The case

    mix and capacity planning problem aims at advancing both the resource efficiency and the health

    service level. In order to maximize the hospital resource efficiency, an optimization (ILP) model

    is developed to solve the optimal case mix pattern and the associated resource allocation scheme

    in a deterministic manner. However, the existing variability within a health care system not only

    affects the resource utilization but further impacts the health service delivery. Hence, we take the

    variability into account to absorb its effects and to improve the time-phased resource allocation.

    Moreover, a discrete-event simulation model is built to evaluate the operational performance and

    to analyze how to enhance the trade-offs between efficiency and service.

    A numerical example is applied to illustrate the efficiency of the proposed solution methodology.

    Then, it would be more valuable to apply this methodology to a real case situation in a Belgian

    hospital, in which the seasonality of the patient arrivals can be included instead of considering an

    identical patient demand over the whole year in the numerical example. The time-varying patient

    demands of some pathologies reflect the real situation in a hospital, but may challenge the time-

    phased resource allocation of the planning problem. To cope with this issue, we might adopt the

    30

  • flexible master surgery scheduling, i.e., generating the seasonal master surgery schedules, which

    is helpful to increase the resource utilization and to reduce the patient waiting list.

    This paper works on a study of the case mix and capacity planning for elective inpatients, while

    emergency patients are excluded from the discussion since the case mix planning is infeasible for

    emergency patients because of their random arrival property. Actually, according to a prediction

    for the amount of emergencies, it is assumed that there are a certain number of reserved resource

    capacities exclusively utilized by the emergency patient in our healthcare setting. Nevertheless, it

    is feasible to incorporate the emergency admission at the resources planning level to improve the

    time-phased resource allocation, which may advance both the resource utilization and the patient

    service. Other possible extensions can be formed through including some other resources such as

    intensive care beds or by integrating the nursing staff planning and scheduling.

    In addition, the studied case mix and capacity planning problem considers a whole hospital as the

    main unit of analysis. The hospital planning decides a tactical master plan for elective inpatients

    and the resource allocation over a whole hospital, and the performance evaluation is also carried

    out from a tactical perspective. However, the planning problem can be extended over a hospital

    network in a certain area, and the tactical case mix and capacity planning can be combined with

    the operational patient scheduling to form an efficient health care production framework.

    Acknowledgements

    The authors acknowledge the support given to this project by the Fonds voor Wetenschappelijk

    Onderzoek (FWO)-Vlaanderen, Belgium under contract number G.0456.08.

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