JOINT ANNUAL MEETING OF IMMUNOLOGY OF THE AUSTRIAN … · arising not only in basic innate and...
Transcript of JOINT ANNUAL MEETING OF IMMUNOLOGY OF THE AUSTRIAN … · arising not only in basic innate and...
Österreichische Gesellschaft für Allergologie und Immunologie&
Deutsche Gesellschaft für Immunologie
JOINT ANNUAL MEETING OF IMMUNOLOGY
OF THE AUSTRIAN AND GERMAN SOCIETIES
Lecture Centre of the Vienna General HospitalVienna, Austria
Wednesday, September 3 – Saturday, September 6, 2008
Final Programme
www.medacad.org/oegai2008
ALLERGIE LAUF
Sonntag, 7. September 2008 Schlosspark Schönbrunn
Hiermit laden wir Sie ganz herzlich dazu ein, im Anschluss an den Kongress „Joint Annual Meeting of Immunology, Wien, 3.-6. September 2008“, am
ALLERGIE LAUF am Sonntag, 7. September 2008 im SCHLOSSPARK SCHÖNBRUNN,
einer der schönsten Parkanlagen Wiens, teilzunehmen. Nach dem Startschuss von Nobelpreisträger Peter Doherty geht es durch den Schlosspark Schönbrunn, durch Alleen mit barocker Gartenbaukunst, und vorbei am Schloss Schönbrunn, einem der bedeutendsten Kulturdenkmäler Österreichs, einst bewohnt von Kaiserin Sissi und heute ein beliebtes Ausflugsziel vieler Wiener und Wienbesucher. Sie können unter verschiedenen Distanzen wählen und auch im Team laufen. Das Tempo bleibt Ihnen überlassen: gemütlich oder mit sportlichem Ehrgeiz, dazu wird es eine exakte elektronische Zeitmessung geben. Ob Kongressteilnehmer oder nicht - es sind alle eingeladen, mit zu laufen. Im Anschluss an den Lauf folgen als Krönung des Tages und als Belohnung für Ihren sportlichen Einsatz und das tüchtige anfeuern Ihrer Fans, die After Running Party, die Siegerehrung, eine Tombola, ein Buffet reich an köstlichen typisch österreichischen Gerichten, und eine Musikshow. Es unterhalten Sie Harry Sonnek und der legendäre Dave Dee, der mit seinen besten Songs aus den 60ern aus London zu uns kommen wird und für die richtige Partystimmung sorgen wird. Zur After Running Party sind alle Läufer und deren Begleiter ganz herzlich eingeladen. Bitte nutzen Sie die Möglichkeit der Online-Anmeldung auf www.medacad.org/oegai2008 unter „Allergy Run“ sobald als möglich, damit Sie sich Ihr, in der Gebühr inkludiertes, Erinnerungs- T-Shirt in der richtigen Größe sichern. Auf der Homepage finden Sie auch alle mit dem Lauf verbundenen Informationen, sowie den vorläufigen Streckenplan.
Wir freuen uns auf zahlreiche Anmeldungen!
www.bundesgaerten.at
Österreichische Gesellschaft für Allergologie und Immunologie&
Deutsche Gesellschaft für Immunologie
JOINT ANNUAL MEETING OF IMMUNOLOGY
OF THE AUSTRIAN AND GERMAN SOCIETIES
Lecture Centre of the Vienna General HospitalVienna, Austria
Wednesday, September 3 – Saturday, September 6, 2008
Final Programme
www.medacad.org/oegai2008
Table of Contents
General
Patronage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2
Acknowledgements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2
Welcome Addresses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3
Committees – Board – Organisation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5
Programme at a Glance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6
Scientific Programme
- Wednesday, September 3, 2008 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8
- Thursday, September 4, 2008 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9
- Friday, September 5, 2008 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15
- Saturday, September 6, 2008 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20
Poster Viewing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25
Business Meetings . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26
Satellite Lunch Symposia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27
Information on Posters . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28
Information for Speakers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29
Information
Congress Information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30
Registration Fees . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32
General Information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33
Venue . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35
Social Events . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37
Underground Map . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38
City Map . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39
Exhibition
Exhibition – General Information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 40
List of Sponsors, Exhibitors and Advertisers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41
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Patronage
Under the Patronage of
Dr. Alfred GusenbauerFederal Chancellor of the Federal Republic of Austria
Dr. Johannes HahnFederal Minister for Science and Research
Dr. Andrea KdolskyFederal Minister for Health, Family and Youth
Mag. Sonja WehselyExecutive City Councillor for Public Health and Social Affairs
Acknowledgements
The Joint Annual Meeting of Immunology gratefully acknowledges the support of the followinginstitutions, companies and organisations (list correct as per date of printing):
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Welcoming Addresses
Unquestionably a high level of health care is the core element of our modernwelfare system as we know it. It is therefore our duty as politicians to securethe basis for its long-term financial stability. Furthermore, we must create aninstitutional and legal framework to guarantee universal and non-discrimina-tory access to all forms of treatment. Nobody should be excluded or left behind. Only under these conditions can health-care professionals fulfil theiressential duty and live up to their oath i.e. helping people.
Public opinion polls show the high satisfaction of Austrians with our nationalhealth care system. But no society can satisfy itself with self appreciation. Many challenges lieahead of us. Some are institutional, financial, others are scientific. This congress will help to pro-mote knowledge and hopefully inspire all working in your field.
On behalf of the Austrian government it is my pleasure to welcome you here in Austria and inparticular at this “Joint Annual Meeting of Immunology”.
Dr. Alfred GusenbauerFederal Chancellor of the Federal Republic of Austria
More than 1000 participants at the „Joint Annual Meeting of lmmunology"give invigorating proof of the importance and international reputation of theSocieties of Allergology and Immunology in Austria and Germany on the onehand and the Vienna Medical Academy in the fields of education/research aswell as conference and association management – an organisation dedicatedto serving the needs of the medical non-profit community - on the other. Asminister of Science and Research it is good news for me that internationalexperts are discussing such pressing topics as vaccination, infection and allergy just now in Austria. That means new incentives for the Scientific Com-
munity especially in our country and the opportunity to expand international networking. Theseissues are of great relevance for nearly all of us and the expectations are very high, if you only thinkof tumor immunology for example. May the meeting be a successful one with impressing resultsand congratulations on bringing together university professors of international reputation in thisfield in Vienna for the first time. In this way the meeting is a great recognition of Vienna as an im-portant medical research place.
Dr. Johannes HahnFederal Minister for Science and Research
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Welcoming Addresses
Dear colleagues and scientific friends,
It is our great pleasure to welcome you to the Joint Annual Meeting of the Austrian and the Ger-man Societies of Immunology in Vienna.
The annual conferences of our societies allow for an exchange of thoughts and information on cut-ting edge developments taking place in the immunological laboratories worldwide. The format ofa joint annual conference allows for an expansion of this exchange into a neighbouring countryand likewise fosters new and/or permits to renew longstanding scientific and social relationships.
With this meeting we are aiming to delineate the latest progress in our field, focusing on mattersarising not only in basic innate and adaptive immunity, but also clinical immunology includingnovel therapeutic approaches. The scientific committee has invited outstanding scientists to pres-ent their thinking and to summarize data on their advances in plenary sessions and introductionsto workshops. Within workshops and during the poster sessions, there will be ample opportunityespecially for students and postdoctoral fellows to present their newest research results and thusa broad array of work which is performed in the realm of the hosting societies and beyond.
We have made all efforts to create a scientific program that meets your expectations. In additionyou shall enjoy Vienna´s ambience and hospitality, the unique culture and spirit which so fewother cities have to offer.
With best wishes for a scientifically exciting and stimulating meeting and
mit herzlichen Grüßen,
Yours
Stefan Meuer & Josef Smolen
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Committees – Board – Organisation
Congress Committee
Stefan C.W. Meuer Josef SmolenAndreas Radbruch Marcus SäemannReinhold E. Schmidt
Local Organising Committee
Irmgard Förster Marcus SäemannBeatrix Grubeck-Loebenstein Reinhold SchmidtErika Jensen-Jarolim Josef SmolenStefan C.W. Meuer Hannes StockingerWinfried Pickl Rudolf ValentaAndreas Radbruch Gerhard Zlabinger
ÖGAI Executive Committee
Josef Smolen (President) Gernot Achatz (Board Member)Rudolf Valenta (President Elect) Hans-Peter Brezinsek (Board Member)Beatrix Grubeck-Loebenstein (Past President) Roswitha Gruber-Sgonc (Board Member)Marcus Säemann (Secretary General) Erika Jensen-Jarolim (Board Member)Winfried Pickl (Deputy Secretary) Johannes Stöckl (Board Member)Tamara Kopp (Secretary Protocol) Martin Thurnher (Board Member)Barbara Bohle (Treasurer) Othmar Förster (Honorary President)
DGfI Executive Committee
Stefan C.W. Meuer (President) Reinhold Förster (Board Member)Andreas Radbruch (President Elect) Stefan H. E. Kaufmann (Board Member)Reinhold E. Schmidt (Past President) Heidrun Moll (Board Member)Werner Solbach (Secretary General) Yvonne Samstag (Board Member)Christian Bogdan (Board Member) Burkhart Schraven (Board Member)Barbara Bröker (Board Member) Hans Dieter Volk (Board Member)Stefan Ehlers (Board Member) Hans-Martin Jäck (Board Member)Irmgard Förster (Board Member)
Conference Organisation, Abstract Management, Sponsoring
Vienna Medical AcademyMs. Marieke HodelAlser Strasse 4, 1090 Vienna, AustriaPhone: +43 1 405 1383-10; Fax: +43 1 407 8274E-mail: [email protected]
Exhibition Management Hotel Accomodation
Medizinische Ausstellungs- und Mondial Congress & EventsWerbegesellschaft MAW Operngasse 20bFreyung 6 1040 ViennaA-1010 Vienna, Austria Phone: +43 1 58804-0Phone: +43 1 536 630 Fax: +43 1 58804-185Fax: +43 1 535 60 16 Email: [email protected]: [email protected]
Congress Venue
Lecture Centre of the Vienna General Hospital(Allgemeines Krankenhaus - AKH)Währinger Gürtel 18-201090 Vienna, Austria
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Scientific Programme – Wednesday, September 3, 2008 8
Time Lecture Hall 1
15.00-
15.10
WelcomeChair: S. Meuer, J. Smolen
Welcoming addresses by
Stefan Meuer, President DGfI
Josef Smolen, President ÖGAI
15.10-
15.25
Karl Landsteiner (1868-1943) - An Austrian Immuno-PathologistGabriela Schmidt-Wyklicky
15.25-
15.45
Awarding of the Landsteiner Price of the DGfI to Max CooperLaudatio: Andreas RadbruchAward Lecture: Max Cooper
15.45-
16.05
Awarding of the Landsteiner Medal of the ÖGAI to Ron GermainLaudatio: Clemens ScheineckerAward Lecture: Ron Germain
16.05-
16.20
Rainer Honeck, Concert Master of the The Vienna Philharmonic Orchestra: J.S. Bach
16.20-
16.50
Keynote Lecture:Nobel laureate Peter Doherty
16.50-
17.00
Rainer Honeck, Concert Master of the Vienna Philharmonic Orchestra: F. Kreisler
17.00-
17.15
Opening by Wolfgang Schütz (Rector of the Medical University of Vienna)
17.15 Welcome Drinks
Scientific Programme – Thursday, September 4, 2008 9
Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3
08.15-
09.30
Parallel Symposium 1:T-Cell SignalingChair: W. Pickl, D. Kabelitz
Parallel Symposium 1:Innate Immunity: Antigen-Presenting-CellsChair: G. Stingl, B. Broeker
Parallel Symposium 1:Tumor ImmunologyChair: E. Jensen-Jarolim, G. Riethmüller
Molecular determinants of Inside-out signaling in T-cellsB. Schraven
DC dependent maintenance of peripheralregulatory T-cellsS. Beissert
Human Self/Tumor Antigens and TumorImmunosurveillanceO.J. Finn
From T cell activation signals to signalingcontrol of anti-cancer immunityJ. Penninger
Role of antimicrobial peptides in triggeringautoimmunityM. Gilliet
The immune response to sporadic cancerT. Blankenstein
Deciphering TCR ligand discrimination bycombining experiments, computer modeling, and predictive simulationsR. Germain
TLR-activated dendritic cells as effectorcells of the immune responseG. Stingl
Development of DNA vaccination strate-gies for pediatric cancersH.N. Lode
09.30-
10.30Coffee Break / Poster Viewing / Exhibition
Scientific Programme – Thursday, September 4, 2008 10
Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3 Lecture Hall 4 Lecture Hall 5
10.30-
12.15
T-Lymphocytes IChair: G. Schütz, H. Wolf
Autoimmunity IChair: H. Strobl, G. Beilhack
Tumor ImmunologyChair: J. Singer, T. Weichhart
ImmunomodulationChair: K. Loser, W. Berger
Innate Immunity: Anti-gen-Presenting CellsChair: N. Romani, H. Schild
1. Increased Th17 anddecreased CD4+FoxP3+T regulatory cells in thirdtrimester pregnancieswith pre-eclampsiaB. Santner-Nanan, M. Peek, L. Richarts, R. Khanam, E. Zhu, B.Fazekas de St. Groth, R. K. Nanan
9. The role of B cells intissue draining lymphn-odes for the develop-ment of collageninduced arthritis (CIA)C. Scheinecker, A. Rapp, M. Bonelli, A. Savitskaya, J. S. Smolen
17. Higher avidity ofTCR-gene-modified Tcells by using parts ofthe murine constant TCRregionsD. Sommermeyer, W. Uckert
25. Regulation of homingreceptor expression inCD4+ T cellsB. A. Ratsch, C. Doebis,S. Jennrich, S. Floess, A. Hamann, U. Syrbe
33. Targeting ofHaemagglutinin antigento C-type Lectins onhuman Dendritic Cellselicits different T cell re-sponses in vitroG. F. Heidkamp, F. Nimmerjahn, A. Piperno, H. Zebroski,R. M. Steinman, M. C. Nussenzweig, D. Dudziak
2. Blockade of induciblecostimulator (ICOS) in-hibits accumulation ofpolyfunctionalTh1/Th17cCells and pre-vents autoimmune arthri-tisO. Frey, J. Meisel, L. Bruns, A. Hutloff, L. Morawietz, T. Kamradt
10. T helper cells only in-duce acute inflammationbut B cells are necessaryfor the induction ofchronic Antigen-inducedArthritisM. Janke, T. Hohnstein,L. Morawietz, A. Scheffold
18. Reprogramming Tcells to become MHC in-dependent - electropo-ration of RNA encodingchimeric antigen recep-torsN. Schaft, T. Schunder,C. Krug, S. Reuter, D. Kosmides, H. Abken,M. Kershaw, E. Kämpgen, G. Schuler,J. Dörrie
26. Regulated releaseand functional modula-tion of junctional adhe-sion molecule A bydisintegrin metallopro-teinasesJ. Pruessmeyer, R. Koenen, L. Fraemohs,O. Soehnlein, C. Weber,A. Ludwig
34. PPARgamma en-hances uptake andcross-presentation ofsoluble antigen in den-dritic cellsS. Hucke, J. Floßdorf, I. Dani, D. Thimm, A. Kautz, C. Kurts, P. Knolle, L. Klotz, S. Burgdorf
3. IRF4 is essential forIL-21-mediated induc-tion, amplification andstabilization of the Th17phenotypeM. Huber, A. Brüstle, A. Guralnik, A. Mahiny, E. von Löw, M. Lohoff
11. Crucial role of CCR4in the development ofexperimental CNS au-toimmune disease bymodulation of Treg cellcompartimentalizationJ. Alferink, D. M. Otte,K. Poppensieker, Ö. Yilmaz, A. Mildner, M. Prinz, W. Maier, A. Zimmer
19. Memory CD8+ T-cellmediated tumor rejectionis impaired in NKG2D-dysfunctional miceM. C. Banerjea, D. Sigurdardottir, B. Pömmerl, H. Rammensee, A. Steinle
27. Ontogeny of Langer-hans cells in prenatalhuman skinC. Schuster, C. Vaculik,C. Fiala, W. Eppel, S. Meindl, M. Imhof, A. Elbe-Bürger
35. Genomic RNA ofhuman rhinovirus - a”semi-danger-signal” fordendritic cellsC. Schrauf, S. Kirchberger, O. Majdic, J. Seipelt, J. Stöckl
4. Acid sphingomyeli-nase is a critical regula-tor of cytotoxic granulesecretion by primary TlymphocytesJ. Herz, J. Pardo, H. Kashkar, M. Schramm, E. Kuzmenkina, E. Bos,K. Wiegmann, R. Wallich, P. J. Peters,S. Herzig, E. Schmelzer,M. Krönke, M. M. Simon,O. Utermöhlen
12. Antigen-specificTGF -induced Treg sup-press Th17-mediatedautoimmune diseaseE. N. Huter, G. H. Stummvoll, E. M. Shevach
20. Rejection of estab-lished cancer: Lack ofIFN- , TNF- and Fas-lig-and but not perforin byeffector CD8+ T cells al-lows cancer to progressJ. J. Listopad, G. Willimsky, B. Silkenstedt, T. Kammertöns, T. Blankenstein
28. Requirement ofCCL17 for progressionof atopic dermatitis andcontact hypersensitivityin miceS. Stutte, N. Gerbitzki, I. Förster
36. Antagonism betweenGATA-1 and vitamin D3receptor in myelopoisisand dendritic cell subsetdifferentiationS. Taschner-Mandl, F. Göbel, M. Kumerz, J. Jurkin, C. Vaculik, S. Richter, C.Bieglmayer, A. Elbe-Bürger, H. Strobl
5. Adenosine regulatesCD8 T cell priming by in-hibition of membrane-proximal T cell receptorsignalingD. Stabenow, C. Linnemann, F. A. Schildberg, A. Schurich, S. I. Hegenbarth, L. Diehl, E. Endl, S. Lacher, C. E. Müller, J. Frey, L. Simeoni, L. Simeoni, B. Schraven,P. A. Knolle
13. The pathogenic roleof HnRNP-A2 in Pris-tane-induced arthritisM. H. Hoffmann, C.Baumann, B. Meyer, G. Steiner
21. Defects of the anti-gen processing machin-ery leading to T cellresistance of melanomacellsM. Keller, F. Ebstein, A. Paschen, E. Bürger,D. Schadendorf, P. M. Kloetzel, U. Seifert
29. Acid sphingomyeli-nase is required for effi-cient phago-lysosomalfusionM. Schramm, U. Karow,A. Haas, M. Krönke, O. Utermöhlen
37. Function of hypoxia-inducible factor (HIF)-1in dendritic cellsT. Köhler, R. S. Johnson, H. Weighardt, I. Förster
6. pSMAC formation inhuman peripheral bloodT-cells requires localiza-tion of the actin-bundlingprotein L-plastin to theimmunological synapseG. Wabnitz, P. Lohneis,H. Kirchgessner, Y. Samstag
14. The autoimmune reg-ulator Roquin-a cofactorfor miRNA function?E. Glasmacher, K. P. Höfig, E. Kremmer,V. Heissmeyer
22. Tumor-specific Thelper cells regulatetumor dormancy orprogress multistage car-cinogenesis through Tcell cytokinesH. Braumueller, T. Wieder, N. Bauer, M. Rocken
30. Phenotypic and mo-lecular analysis of anHLA Class II deficientpatient reveals a ho-mozygous nonsensemutation in the CIITAgene at amino acid posi-tion 381K. G. Schmetterer, M. G. Seidel, U. Körmöczi, K. Schwarz, S. Matthes-Martin, P. Steinberger,W. F. Pickl
38. Distinct mechanismof antigen routing andcross-presentation inLSECA. K. Schurich, J. Böttcher, S. Burgdorf,P. Penzler, S. Hegenbarth, D. Stabenow, A. Dolf, E. Endl, C. Kurts, P. A. Knolle
Scientific Programme – Thursday, September 4, 2008 (continued) 11
Lecture Hall 1 Lecture Hall 2 Lecture Hall 3 Lecture Hall 4 Lecture Hall 5
7. The effect of thymec-tomy in early childhoodon the naive T cell com-partment in later lifeM. Prelog, M. Keller, R. Geiger, A. Brandstaet-ter, R. Würzner, B. Grubeck-Loebenstein,L. B. Zimmerhackl
15. OSCAR, a key co-stimulation molecule forosteoclasts, is inducedin patients with rheuma-toid arthritisS. Herman, G. Krönke,R. Müller, J. Zwerina, K. Redlich, G. Schett
23. Identification oftumor antigens using an-tibodies induced by den-dritic cell (DC) basedvaccinesJ. Leitner, A. Stift, J. Friedl, R. Pfranger, P. Steinberger, K. Pfistershammer
31. Different mecha-nisms of immunosup-pression caused byCyclosporine A (CsA)and FK506T. Giese, C. Sommerer,C. Jacobi, M. Zeier, S. Meuer
39. Skin dendritic cellspresent lipid antigens tonatural killer T cellsP. Stoitzner, I. F. Hermans, N. Romani
8. Clonal evolution of theeffector T cell repertoireD. Zehn, M. J. Bevan
16. Imaging immune-neuronal interactions inexperimental auto -immune encephalo -myelitis using intravitaltwo- photon microscopyV. Siffrin, J. Herz, T. Leuenberger, A. U. Brandt, H. Radbruch, R. Niesner, C. Infante-Duarte, F. Zipp
24. Serological relation-ship between cutaneoushuman papillomavirustypes 5, 8 and 92A. Handisurya, C. Schellenbacher, R. Gambhira, S. Shafti-Keramat, O. Forslund, M. Favre, R. Kirnbauer
32. Identification of threenovel genes as biomarker for monitoringanti-TGFbeta therapyS. Classen, C. Muth, D. Eggle, M. Beyer, T. Zander, A. Staratschek-Jox, J. L. Schultze
Time Lecture Hall 1
12.15-
13.45
Satellite Lunch Symposium - RocheB cell: Promising target in autoimmune diseasesChair: J. Smolen
The biology of the B cell in autoimmune diseasesA. Radbruch
Clinical experiences with B cell therapiesT. Dörner
Safety: Experiences with RituximabH-P. Brezinsek
12Scientific Programme – Thursday, September 4, 2008
Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3 Lecture Hall 4 Lecture Hall 5
14.00-
15.30
T-Lymphocytes IIChair: M. Lohoff, A. Thiel
Vaccines & AdjuvantsChair: B. Grubeck, S. Weiss
Signal TransductionChair: T. Bürckstürmer, T. Stulnig
NK cellsChair: C. Watzl, M. Fischer
Veterinary ImmunologyChair: A. Saalmüller, M. Müller
40. Stability and flexibil-ity of CD4 T cell differen-tiation programs in vitroand in vivoA. N. Hegazy, H. Hengartner, R. M. Zinkernagel, A. Radbruch, M. Löhning
48. Improvement of theImmunogenicity of aHIV-1 Clade C Candi-date Vaccine increasingGag, Pol, Nef and EnvSpecific T-Cell Re-sponsesJ. Wild, J. Koestler, S. Bredl, K. Boeckl, R. Wagner
56. Oxidation of cofilinmediates T cell hypore-sponsiveness under ox-idative stress conditionsM. Klemke, G. Wabnitz,F. Funke, B. Funk, H. Kirchgessner, Y. Samstag
64. The stress-inducibleendogenous danger sig-nals HSP70 and MICAsynergistically activatethe cytotoxic effectorfunctions of human NK cellsL. Elsner, P. F. Flügge, J. Lozano, V. Muppala,S. Y. Demiroglu, D. Malzahn, H. Bickeböller,G. Multhoff, L. Walter, R. Dressel
72. Charakterization ofthe chicken CD40-CD40L system unsingthe RCAS retroviral genetransfer technologyK. Schenk-Weibhauser,J. Young, B. Kaspers, S. Kothlow
41. On the role ofadipokines in Th2 lym-phocyte polarizationA. Batra, B. Okur, J.Ihbe, T. Stroh, R. Glauben, I. Fedke, M. Zeitz, B. Siegmund
49. Safety and immuno-genicity in a phase Idose-escalation BPV-1VLP vaccine trial inhorsesR. Kirnbauer, S. Brandt,S. Shafti-Keramat, E. K. Hainisch
57. The orphan adapterprotein SLY1 as a novelanti-apoptotic protein re-quired for thymocyte de-velopmentB. Reis, D. Finkenstaedt,D. K. Finlay, D. A. Cantrell, K. Pfeffer,S. Beer
65. Regulation of NK cellactivity through extracel-lular HLA-B-AssociatedTranscript 3E. Pogge von Strand-mann, V. Simhadri, K. S. Reiners, H. P. Hansen, A. Engert
73. Analysis of potentialantiviral MX activity inthe chickenB. Schusser, N. Penski,A. Reuter, G. Kochs, P. Staeheli, B. Kaspers,S. Kothlow
42. In vivo generatedTh17 cells have a stablememory for IL-17 ex-pressionM. H. Lexberg,I. Albrecht, A. Förster, A. Richter, A. Radbruch,H. D. Chang
50. Characterisation ofeffects on growth ofStaphylococcus aureusmediated by specificIgGsB. Tosetti, E. Glowalla,M. Krönke, O. Krut
58. Micropatterning ofCD4 in the live cellplasma membrane re-veals novel bindingmechanisms to LckM. Schwarzenbacher,M. Kaltenbrunner, M. Brameshuber, C. Hesch, W. Paster, J. Weghuber, B. Heise,A. Sonnleitner, H. Stok-kinger, G. J. Schütz
66. Natural killer cell’sactivation by Im-munomodulin for treat-ment strategy ofrecurrent genital herpesV. Garib, U. Djabborov,Y. Rasul-Zade
74. MHC typing in swine:SLA class I and class II-allele distribution in Aus-trian Large White,Landrace, and Pietrainbreeding stocksS. E. Hammer, J. Deutsch, B. C. Rütgen, S. Groiß,W. Gerner, S. Müller, A. Saalmüller
43. Role of HDAC in Thelper cell developmentR. Glauben, E. Sonnenberg, I. Fedke,P. Mascagni, M. Zeitz, B. Siegmund
51. Analysis of themechanisms mediatingdendritic cell-based vac-cination against Leish-mania majorJ. K. Schnitzer, C. Hambrecht, M. Fajardo-Moser, K. A. Remer, H. Moll
59. Stat3 serine 727phosphorylation uponactivated TLR bindingpromotes viaMyD88/TRIF safekeep-ing of IL-1betaS. Dreher, F. Schmitz, R. Ferstl, S. Spiller, J. Marges, A. Heit, I. För-ster, R. Lang, H. Wagner, C. J. Kirschning
67. Decision making inNK cellsD. Urlaub, S. Mesecke,H. Busch, R. Eils, C. Watzl
75. Porcine coccidiosis -adaptive immune re-sponse mechanismsagainst Isospora suisH. L. Worliczek, W. Gerner, A. Saalmüller,A. Joachim
44. HumanCD4+CD25+Foxp3+ regu-latory T cells efficientlyinhibit GvHD induction ina humanized mousemodelC. Becker, J. Kubach,C. Taube, C. Becker, K. Michel, K. Reifenberg,H. Jonuleit
52. Virus-like particles: Acell-free antigen-pre-senting platform modu-lating lymphocyteactivation in vitro and invivoH. J. Kueng, V. M. Leb,D. Haiderer, G. Raposo,C. Thery, S. V. Derdak, K. G. Schmetterer, A. Neunkirchner, C. Sillaber, B. Seed, W. F. Pickl
60. Carma1/Bcl10/Malt1Complexes TransmitITAM-coupled NK CellReceptor Signals for NF-B and MAPK ActivationO. Groß, C. Grupp, C. Steinberg, S. Zimmermann, D. Strasser, N. Hannesschläger, W. Reindl, C. Peschel,A. Krug, J. Ruland
68. Natural killer cells aremodulated in patientswith neuroimmunologicdisorders in response totreatment with intra-venous immunoglobulinC. Jacobi, M. Claus, B. Wildemann, J. Römisch, C. Watzl, S. Meuer, T. Giese
76. Potential diagnosticmarkers for subclinicalendometritis in cows:TNF-alpha, IL-1 alpha,IL-1 beta, and IL-8C. Gabler, M. Drillich, C. Fischer, C. Holder, W. Heuwieser, R. Einspanier
45. Mathematical model-ing of the diversity of theimmunological synapseM. T. Figge, M. Meyer-Hermann
53. Priming and boostingof melanA-specific Tcells - in vitro studies onthe importance of anti-gen-presentation densityJ. Dörrie, N. Schaft, V. Wellner, C. Wohn, T. Schunder, I. Müller, E. Kämpgen, G. Schuler
61. Functional analysisof the riboflavin kinaseand its role in TNF-in-duced signallingB. Yazdanpanah, C. Pongratz, K. Wiegmann, H. Kashkar, M. Krönke
69. Myeloid-Derived“Suppressor” Cells ex-press Rae-1 and activateNK cellsA. Cerwenka, E. Schlecker, I. Galani, N. Nausch
77. Toll-like receptor ex-pression and bacterialstrain dependentchemokine response in aprimary bovine colonicepithelial cell culturemodelP. S. Bridger, M. Mohr,J. Fröhlich, H. Metcalfe,D. Werling, G. Baljer,C. Menge
13Scientific Programme – Thursday, September 4, 2008 (continued)
Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3 Lecture Hall 4 Lecture Hall 5
46. The role of the zincfinger protein MAZR inCD4/CD8 cell fate deci-sions during thymocytedevelopmentS. Sakaguchi, I. Bilic, M. Hombauer, A. Schebesta, W. Ellmeier
54. Propagation-defi-cient LCMV-derived vac-cine vector efficientlytargets dendritic cells toinduce potent T and Bcell responses againstimmunogens of choiceL. Flatz, A. N. Hegazy, A. Verschoor, A. Bergthaler, M. Löhning, D. D. Pinschewer
62. The DEAD-box heli-case DDX3X is a criticalcomponent of the TANK-binding kinase 1-depen-dent innate immuneresponseD. Soulat, T. Buerckstuemmer, S. Westermayer, A. Goncalves, A. Bauch,A. Stefanovic, O. Hantschel, K. L. Bennett, T. Decker,G. Superti-Furga
70. Characterization of anovel, RORgt-expressingmucosal NK cell popula-tionS. L. Sanos, A. Mortha,V. Bui, K. Oberle, A. Diefenbach
78. Analysis of CD28 inhorses and applicationof a polyclonal Ab to in-duce co-stimulationS. Ibrahim, E. Abd El-Gawad, F. Steinbach
47. 2D-DIGE analysis ofenriched secretory lyso-somes of human T andNK cellsH. Schmidt, C. Gelhaus,M. Lettau, M. Nebendahl, M. Leippe, O. Janssen
55. Vaccination withMHC class II-heterolo-gous dendritic cells in-duces protectiveimmunity against Leish-mania majorK. A. Remer, H. Moll
63. Post-transcriptionalregulation of FasL ex-pression: Molecular in-sights into storage,activation-induced mo-bilization and sheddingof a prototypic deathfactorM. Lettau, O. Janssen
71. Specificity of interac-tion between killer cellimmunoglobulin-like re-ceptors (KIR) and MHCclass I molecules of therhesus macaque(Macaca mulatta)P. Kruse, C. Rosner, M. Hermes, L. Walter
79. Species-specificgeneration of immuneregulatory molecules byhost pathogen coevolu-tionR. Kammerer, T. Popp,S. Haertle, B. B. Singer,E. Travanty, Z. Qian, K. V. Holmes, W. Zimmermann
15.30-
16.30Coffee Break / Poster Viewing / Exhibition
14Scientific Programme – Thursday, September 4, 2008
Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3
16.45-
18.00
Parallel Symposium 2:VaccinationChair: M. Müller, H.J. Schild
Parallel Symposium 2:In Vivo ImagingChair: C. Scheinecker, C. Berek
Parallel Symposium 2:ImmunomodulationChair: W. Ellmeier, E. Schmitt
Delineation of plasmablast characteristicsgenerated in steady-state and in systemicimmune responsesH. Mei
The In Situ Dynamics of Innate and Adap-tive Immune Cell Behaviour Revealed ByIntravital Multiphotometry MicroscopyR. Germain
Probing Dendritic cell In vivo FunctionsS. Jung
Towards a coronavirus- based multigenevaccine platformB. Ludewig
In vivo imaging of Germinal Center B CellsA.E. Hauser
Tec kinases in T cell activation and functionL. Berg
Modulating Vaccine Responses with Innate ImmunityB. Pulendran
Non-invasive imaging of inflammation -the quest for specificityA. Wunder
Inducible Foxp3-dependent or -indepen-dent human CD4+ regulatory T Cells.R. Bacchetta
19.00 Welcome Reception at the Vienna City Hall
For more information, please contact us at:Call: +49 (0) 9761/ 406-0 • +31 (0) 43 40 77 310E-mail: [email protected] • [email protected] [email protected]
NUDIST COLONIES.CD-1-nude • NMRI-nude • BALB/c-nude
We’ve improved the availability of our nude mouse strains.
15Scientific Programme – Friday, September 5, 2008
Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3
08.15-
09.30
Parallel Symposium 1:Innate Immunity: RegulationChair: M. Säemann, W. Solbach
Parallel Symposium 1:Mucosal InflammationChair: B. Bohle, D. Männel
Parallel Symposium 1:TransplantationChair: T. Wekerle, R. Schmidt
Innate resistance, inflammation, and cancerG. Trinchieri
Role of epithelial barrier function in allergyP. Brandtzaeg
Antibody-mediated transplant rejectionG. Böhmig
Interferon regulatory factors and innate immunity in early lifeM. Goldman
A prominent role for mucosal cystine/cys-teine metabolism in intestinal immunoreg-ulationS. Meuer
Immune monitoring and therapy in trans-plantation - from bench-to -bedsideH.D. Volk
The mammalian target of rapamycin andinnate immunityT. Weichhart
Tumor Necrosis Factor and the conse-quences of its ablation in vivoS. Nedospasov
Tolerance through mixed chimerism: howclose to clinical application is it?T. Wekerle
09.30-
10.30Coffee Break / Poster Viewing / Exhibition
16Scientific Programme – Friday, September 5, 2008
Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3 Lecture Hall 4 Lecture Hall 5
10.30-
12.15
Allergy IChair: H. Renz, F. Horak
Regulatory Lympho-cytes IChair: L. Klein, T. Wekerle
Alloimmunity & Toler-anceChair: B. Arnold, H. Ankersmit
Pattern RecognitionReceptors & MyeloidCellsChair: S. Bauer, C. Bogdan
Innate Immunity: RegulationChair: M. Zeyda, K. Pfeffer
80. Tracing antigen sig-natures in the human IgE repertoireK. Marth, M. Novatchkova, M. Focke-Tejkl, S. Jenisch, S. Jäger, D. Kabelitz, R. Valenta
88. Analyses of a novelregulatory T cell subsetin patients with SystemicLupus Erythematosus(SLE)M. Bonelli, A. Savitskaya, E. Feierl,S. S. Smolen, C. Scheinecker
96. Role of IL-2 in induc-tion of CD8 T cell toler-ance by LSECA. K. Schurich, M. Berg,A. Limmer, H. J. Schild,L. Diehl, P. A. Knolle
104. Influence of viral in-fection on recognition ofself RNAT. von Thülen, M. Nain,S. Bauer
112. Suppression ofadaptive immune re-sponses by Toll-like re-ceptor ligandsB. Schumak, M. Brock,F. Jüngerkes, G. Hartmann, T. Tüting,P. Knolle, R. Zawatzky, S. Bauer, A. Limmer
81. Stable dust chal-lenge inhibits allergic air-way reactivity throughTLRs 2, 3, 4, 7, 9 and/orother PRRs/TLRsR. Ferstl, S. Spiller, S. Dreher, H. Garn, H. Fehrenbach, E. Von Mutius, H. Renz,H. Wagner, C. J. Kirschning
89. CD4+ CD25high regu-latory T cells suppress Thelper 1 but not T helper2 cytokinesT. Bollinger, A. Bollinger, W. Solbach
97. Proliferation of CD8-positive T cells in the Lu-mina of Rat RenalAllograft Blood VesselsV. Grau, G. Fuchs-Moll,W. Padberg
105. TLR7-dependentrecognition of transferRNAY. Zhao, A. Kaufmann, K. Steinbach, S. Bauer
113. The cytoplasmic tailof CD45 is released fromactivated phagocytesand can act as an in-hibitory messenger for T cellsS. Kirchberger, O. Majdic, S. Blüml, C. Schrauf, J. Leitner, C. Gerner, W. Paster, N. Gundacker, M. Sibilia,J. Stöckl
82. Composition of Bcell receptor classic anti-gen-binding site regu-lates allergic airwayinflammation in a murinemodel of experimentalasthmaS. Kerzel, J. Wagner, T. Rogosch, A. Yildirim, H. Fehrenbach, H. Garn,R. F. Maier, H. W. Schroeder Jr., M. Zemlin
90. Induction of CD25-
Foxp3- regulatory T cellsby chronic antigen stim-ulation in vivoW. Hansen, A. M. Westendorf, J. Buer
98. Dickkopf 3, a novelmodulator of T cell re-sponsesM. Papatriantafyllou,G. Moldenhauer, H. J. Gröne, C. Niehrs,G. J. Hämmerling, T. Oelert, B. Arnold
106. Intrabody mediatedretention of TLR2 andTLR9 in the ER to inhibitchronic inflammationT. Böldicke, S. Dreher,S. Somplatzki, L. Grosse-Hovest, B. Maaß, W. Lindenmaier, H. Wagner, C. Kirschning
114. Molecular mecha-nisms of Staphylococcusaureus-induced au-tophagyK. Sabel, D. Grumme, S. A. Leggio, A. Schnaith, M. Krönke,O. Krut
83. High expression ofinflammatory cytokines,chemokines and their re-ceptors in lungs of miceduring allergic asthmaremission underlies thepersistence of chroniclung inflammationR. Bankoti, L. El-Housseiny, G. Dekan, O. Hoffmann,G. Stingl, M. M. Epstein
91. Transfer of in vitroexpanded humanCD45RA+CD4+CD25high regulatory T cells in-hibits early expansion ofconventional T cells inimmunodeficient Rag2-/-c-/- miceT. J. Boeld, J. Albrecht,K. Doser, R. Eder, J. Stahl,E. Typlt, E. Obermann, R. Andreesen, P. Hoffmann, M. Edinger
99. Toag-1 enables pre-diction of CMV mediatedtransplant tolerance ab-rogationW. Gong, M. Klöpfel, K. Vogt, S. Haase, A. Reutzel-Selke, H. Volk, A. Pascher, B. Sawitzki
107. Analysis of Toll-likereceptor 7 and Toll-likereceptor 9 chimeric mol-eculesJ. Willemsen, P. Yu, S. Bauer
115. 12/15-lipoxygenaseis involved in the limita-tion of inflammation andtissue damage in murinearthritisG. Krönke, J. Katzenbeisser, S. Uderhardt, W. Baum,R. Axmann, J. Zwerina,G. Schett
84. Antigen -specific im-munotherapy inhibitedTh2 via GATA-3 andTh17 cells in an allergicasthma model.N. Zhivkova, R. Karwot,J. H. Maxeiner, P. Scholtes, K. Soo, S. Finotto
92. Long-term vaccina-tion efficiency is inde-pendent of regulatory TcellsG. Gasteiger, W. Kastenmuller, L. Stross, D. H. Busch, T. Sparwasser, I. Drexler
100. Mutated CYLD af-fects the functional stateof dendritic cellsM. Bros, N. Wiechmann,V. Besche, N. Hövelmeyer, S. Reissig, S. Grabbe, A. Waisman,A. B. Reske-Kunz
108. The divergent roleof the mammalian targetof rapamycin (mTOR) indendritic cells subtypesM. Haidinger, T. Weichhart, M. Poglitsch, M. Hecking,M. Zeyda, R. Geyeregger,J. Werzowa, W. H. Hörl,M. D. Säemann
116. Promoter methyla-tion status is changedwith altered DEFB1 geneexpression in COPDE. Andresen, J. Bullwinkel, C. Lange,H. Heine
85. Selective depletionof Foxp3+ cells inDEREG mice allowsfunctional analysis ofregulatory T cells duringexperimental allergic air-way inflammationA. Hartl, K. Lahl, H. Hamad, A. Ö. Yildirim,H. Fehrenbach, R. Teich,H. Garn, H. Renz, B. Lambrecht, T. Sparwasser
93. Retrovirally trans-duced, antigen-specificT cells for therapy oftype 1 diabetesN. Mpofu, N. Saal, M. Hardtke-Wolenski, M. P. Manns, E. Jaeckel
101. Enhanced nuclearexport of NFATc1 andimpaired translocation ofNFATc2 is observed inanergic iTreg generatedby tolerogenic DCH. S. Adler, R. Orth, K. Streck, E. Graulich, K. Steinbrink
109. Mammalian targetof rapamycin (mTOR) or-chestrates the defenseprogram of innate im-mune cellsF. Schmitz, A. Heit, S. Dreher, K. Tittel, J. Mages, T. Haas, A. Krug, K. Janssen, C. V. Kirschning, H. Wagner
117. Macrophage phos-phoproteome dynamicsafter LPS-stimulationand its shaping by theMAPK-PhosphataseDUSP1: a SILAC-basedapproachG. Weintz, J. Olsen, J. Mages, M. Mann, R. Lang
17Scientific Programme – Friday, September 5, 2008 (continued)
Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3 Lecture Hall 4 Lecture Hall 5
86. Molecular and func-tional analysis of theantigen receptor of Bet v1-specific helper T lym-phocytesA. Neunkirchner, V. M. Leb, K. G. Schmetterer, H. J. Kueng, D. Haiderer,S. Mutschlechner, B. Bohle, W. F. Pickl
94. BAC-transgenic micefor depletion of Foxp3+
regulatory T cells:Homeostatic expansionof TregsJ. Suffner, K. Hochweller, N. Garbi,G. Hämmerling
102. Allogeneic dispari-ties in the surface mole-cule immunoglobulin-liketranscript 5 (ILT-5) in-duce potent antibody re-sponses in stem celltransplanted patientsK. Pfistershammer,, A. Lawitschka, J. Leitner,C. Klauser, R. Weigl, G. Böhmig, G. F. Fischer,M. Heemskerk, O. Majdic, W. F. Pickl, H. Greinix, P. Steinberger
110. Hsp60 modulatesneutrophil functionsA. Osterloh, M. Piedavent, F. Geisinger, B. Fleischer, N. Brattig,M. Breloer
118. Prophylactic block-ade of TLR4 or thera-peutic blockade of bothTLR2 and TLR4 protectsmice from Gram-nega-tive infection and subse-quent antibiotic therapyinduced fatal septicshockC. J. Kirschning, G. Elson, R. Ferstl, S. Dreher, T. Müller, M. Freudenberg, B. Daubeuf, H. Wagner,S. Spiller
87. Cloning, expressionand mapping of aller-genic determinants of alphaS1-casein, a majorcow’s milk allergenU. Schulmeister, H. Hochwallner, I. Swoboda, M. Focke-Tejkl, M. Nystrand, A. Harlin, J. Thalhamer,S. Scheiblhofer, W. Keller,B. Niggemann, S. Quirce,C. Ebner, A. Mari, G. Pauli, B. Geller, U. Herz, R. Valenta, S. Spitzauer
95. Lack of Foxp3 Treg-linage marker expressionin mouse epithelial cellsC. T. Mayer, K. Lahl, C. Loddenkemper, T. D. Sparwasser
103. Dendritic cell-acti-vated, endothelial cell-specific CTL recognizinga minor histocompatibil-ity antigen rapidly inducetransplant vasculopathyB. B. Bolinger, D. Engeler, P. Krebs, S. Miller, B. Ludewig, M. Hoffmann, P. Clavien,Y. Tian
111. Spatial separationof cross-presentationand endogenous antigenpresentationS. Burgdorf, C. Schölz,A. Kautz, R. Tampé, C. Kurts
119. Biological charac-terization of mouse betadefensin 14 - an ortho-logue of human beta defensin 3J. Röhrl, T. Hehlgans
Time Lecture Hall 2
12.15-
13.45
Satellite Lunch Symposium - OctapharmaImmune modulation with intravenous immunoglobulin: the established and the advancesChair: S. Meuer
Immunthrombocytopenia as the first model for biological treatment with IVIG in chronic inflammatory and autoimmune diseasesP. Imbach
Intravenous Immunoglobulins: mechanisms of action and options for improvement of therapeutic efficacyF. Nimmerjahn
Basic research in human immunology creates new therapeutic optionsS. Meuer
Discussion and wrap-up
Time Lecture Hall 1
13.00-
13.45
Drittmittelförderung der DFG: Kriterien für eine erfolgreiche AntragstellungChair: Y. SamstagA. Strecker
18Scientific Programme – Friday, September 5, 2008
Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3 Lecture Hall 4 Lecture Hall 5
14.00-
15.30
Infection IChair: F. Schmitz, S. Ehlers
Allergy IIChair: B. Linhart, G. Stary
Regulatory Lympho-cytes IIChair: A. Rosenkranz, H. Schulze-Koops
Mucosal ImmunityChair: R. Förster, M. Pasparakis
B-LymphocytesChair: V. Sexl, T. Winkler
120. Restricted B cell re-ceptor diversity convertsacute into chronic viralinfectionA. Bergthaler, L. Flatz,A. Verschoor, A. N. Hegazy, E. Horvath, M. Holdener,K. Fink, B. Odermatt, D. D. Pinschewer
128. HLA-classII/pep-tide-TCR interactions ofthe single immunodomi-nant T cell epitope of Artv 1, the major mugwortpollen allergenB. Jahn-Schmid, B. Maillere, V. Leb, W. Pickl, G. Gadermaier,F. Ferreira, B. Bohle
136. Generation of in-duced CD8+Foxp3+ reg-ulatory T cells in vitroC. Mayer, K. Lahl, D. Dittlein, V. Wenzel, O. Gassner, J. Stephani,C. Loddenkemper, T. Sparwasser
144. Role of the tran-scription factor PU.1 inhuman lamina propriamacrophagesF. A. Lasitschka, A. Heidtmann, T. Giese,G. Wabnitz, A. Schrödter, J. Winter,A. Ulrich, S. C. Meuer, J. Schröder-Braunstein
152. Swiprosin 1 - posi-tive regulator of BCR in-duced calcium fluxC. Kroczek, C. Lang, A. Avramidou, L. Nitschke, A. Elter, H. M. Jäck, D. Mielenz
121. Interleukin 18 is es-sential for protective im-munity against M.tuberculosis.B. Schneider, D. Korbel, K. Hagens, M. Koch, S. H. Kaufmann, H. Mittruecker, U. E. Schaible
129. Proteomic analysisand mass-spectrometricidentification of differen-tially regulated proteinsin primary human ker-atinocytes by allergensS. Ohnesorge, L. Dietz,P. Pankert, M. Schnoelzer, H. Thierse
137. CD8+CD38+ T-cells:A competent regulatoryT-cell populationA. Bollinger, H. Fehrenbach, T. Bollinger, T. Bollinger,Z. Orinska, S. Bulfone-Paus
145. Role of eosinophilsin TGF-beta expressionin human intestineF. Ulmer, S. C. Bischoff,A. Lorentz
153. Engagement ofCD83 on B cells aug-ments IgG1 response invivoB. Kretschmer, K. Lüthje, S. Schneider, B. Fleischer, M. Breloer
122. Wnt/Frizzled signal-ing in infectious dis-eases: Deciphering therole of FZD1 in my-cobacterial infectionsN. Reiling, T. Endermann, S. Ehlers,J. Neumann
130. Immunosuppres-sion and allergy in organtransplant recipients: ev-idence for insufficientcontrol of allergen spe-cific responsesT. Eiwegger, S. Gruber,C. Geiger, E. Dehlink, T. Frischer, P. Jaksch, W. Klepetko, Z. Szépfalusi
138. Tolerogenic poten-tial of lentivirally trans-duced murine DCoverexpressing antiin-flammatory moleculesV. Besche, N. Wiechmann, S. Trojandt, S. Grabbe,A. B. Reske-Kunz, M. Bros
146. CD4+ Foxp3+ regu-latory T cell expansioninduced by antigen-dri-ven interaction with in-testinal epithelial cellsindependent of localdendritic cellsA. M. Westendorf, D. Fleissner, S. Jung, A. D. Gruber, W. Hansen,J. Buer
154. The analysis of in-travital two-photon im-aging of germinalcentres implies a novellymphocyte migrationand affinity maturationmodelM. Meyer-Hermann, M. Figge
123. Cavity formation intuberculosis is mediatedby interleukin-4 recep-tor-alpha-dependentmechanismsL. Heitmann, T. Schreiber, T. Thye, A. N. McKenzie, A. Cutler, F. Brombacher,R. D. Horstmann, C. G. Meyer, S. Ehlers,C. Hoelscher
131. Long-term toler-ance in IgE-mediated al-lergy through molecularhematopoieticchimerism in a murinemodelU. Baranyi, B. Linhart,N. Pilat, M. Gattringer, C. Klaus, E. Schwaiger,F. Muehlbacher, J. Iacomini, R. Valenta, T. Wekerle
139. IL-27 inhibits thedevelopment of regula-tory T cells via STAT3M. Huber, V. Steinwald,A. Guralnik, A. Brüstle, P. Kleemann, C. Rosenplänter, T. Decker, M. Lohoff
147. Split tolerance afteroral vaccination of micewith recombinant Es-cherichia coli Nissle1917 expressing fimbrialadhesin K88K. A. Remer, M. Bartrow, H. Moll, T. A. Oelschläger
155. Proapoptotic BH3-only proteins Bim andPuma are essential forapoptosis of germinalcenter-derived memoryB cells and antibody-forming cellsS. Fischer,, D. Tarlinton,A. Strasser
124. Immunological inhi-bition of gC1qR/p33, areceptor for C1q, de-creases adherence ofStaphylococcus aureusto microvascular en-dotheliumS. Sethi, M. W. Laschke,J. Roller, L. von Mueller,E. Peerschke, B. Ghebrehiwet, I. Bajric,M. D. Menger, M. Herrmann
132. Generation of anIgE knock-in mouse andits use in systemic ana-phylaxis in vivoP. Yu, W. Lübben, S. Bauer
140. Development of“would-be” regulatory Tcells and defective con-trol of Th2-cytokine pro-duction in natural scurfymutant miceK. I. Lahl, C. T. Mayer, J. Huehn, C. Lodden-kemper, G. Eberl, J. Buer, T. Sparwasser
148. The role of IL-23/IL-17 in Toxoplasma gondiiinduced small intestinalimmunopatologyM. L. Munoz-Roldan, D. Struck, M. Heimesaat,C. Hoelscher, U. Mueller,Y. Iwakura, N. Ghilardi,O. Liesenfeld
156. Identification of achemokine receptor pro-file characteristic for me-diastinal large B-celllymphomaU. E. Höpken, I. Anagnostopoulos, M. Broemer, C. Scheidereit, K. Joehrens, M. Hübler,H. Stein, M. Lipp, B. Dörken, A. Rehm
125. The fibrin-derivedpeptide B 15-42 (FX06)for treatment of capillaryleakM. Gröger, W. Pasteiner,G. Ignatyev, U. Matt, S. Knapp, P. Friedl, D. Zinkl, K. Zacharowski,R. Hofer-Warbinek, P. Petzelbauer, S. Reingruber
133. Murine plasma andnon-plasma B cells ex-press different IgE reper-toiresT. Rogosch, S. Kerzel, L. Sikula, R. Maier, M. Zemlin
141. TLR2 ligands act directly on Treg to abro-gate suppression ofCD4+CD25- T cellsH. Oberg, M. Juricke, S. Ussat, H. Ly, D. Kabelitz, D. Wesch
149. The mesentericlymph node regulatesthe amplitude of IgA secretion in the drainedarea: potential role of thespleen in the immune response against orallyapplied cholera toxinA. Hahn, N. Thiessen, R. Pabst, M. Ahrendt, U. Bode
157. The adapter proteinSLy2 represents a newlyidentified regulator of cy-toskeletal rearrange-mentsM. L. von Holleben
19Scientific Programme – Friday, September 5, 2008 (continued)
Time Lecture Hall 2
18.00-
19.30
General Assembly DGfIChair: S. Meuer
Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3 Lecture Hall 4 Lecture Hall 5
175. Immunopathologi-cal basis of lymphocyticchoriomeningitis virus-induced chorioretinitisand keratitisM. Zinkernagel, P. Krebs,B. Bolinger, S. Miller, B. Ludewig
134. Induced ablation ofmast cells in adult mice:Slow recovery of mastcell populations in thetissues.J. Scholten, A. Gerbaulet, B. Hiller,W. Muller, T. Krieg, T. Buch, A. Waisman, K. Hartmann, A. Roers
142. Influence ofCD4+CD25+ regulatoryT cells on thetransendothelial migra-tion of CD4+CD25- TcellsT. Bedke, M. Kretz, K. Mahnke, A. H. Enk
150. The role of CXCR5in antigen-independentdevelopment and anti-gen-dependent matura-tion of nose-associatedlymphoid tissue (NALT)J. Krege, S. Seth, S. Hardtke, A. MarquesDavalos-Misslitz, R. Förster
158. Antigen receptor tailclue of class-switchedmemory B cellsN. Engels, C. Heemann,L. König, T. Tsubata, S. Griep, V. Schrader, J. Wienands
127. CD8 T cell-medi-ated immune responsesagainst cross-presentingliver sinusoidal endothe-lial cells leads to hepati-tisD. Stabenow, K. Gärtner, M. Svorcova,M. Odenthal, H. Dienes,U. Protzer, P. A. Knolle
135. Timothy grasspollen major allergen Phlp 1 - a protease?K. Röschmann, P. König, A. J. Ulmer, A. Petersen
143. Expansion of im-mune-suppressiveV 9V 2 T cells as a novelregulatory mechanism ofIL-12 secreting dendriticcellsM. W. Traxlmayr, A. M. Dohnal, D. Wesch,D. Kabelitz, T. Felzmann
151. T cell-specific dele-tion of gp130 rendersthe highly susceptible In-terleukin-10 deficientmouse mutant resistantto intestinal nematodeinfectionN. Fasnacht, M. C. Greweling, M. Bollati-Fogolin,, A. Schippers,, W. Müller,
159. Role of basophils inimmunological memoryresponsesA. J. Denzel, U. Maus,M. Rodriguez Gomez, M. Niedermeier, Y. Talke,N. Göbel, M. Mack
15.30-
16.30Coffee Break / Poster Viewing / Exhibition
Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3
16.45-
18.00
Parallel Symposium 2:InfectionChair: S. Knapp, I. Förster
Parallel Symposium 2:Adaptive Immunity: RegulationChair: H. Stockinger, L. Klein
Parallel Symposium 2:Adaptive Immunity: B-CellsChair: G. Zlabinger, H-M. Jäck
Origin of CD8+ effector and memory T cellsubsetsD.H. Busch
Innate and adaptive IL-17 in the control ofimmune responsesB. Stockinger
Transcriptional control of B cell develop-mentM. Busslinger
Mutual host pathogen reactions in tuber-culosisU. Schaible
Autoregulatory circuits in inflammatory T cell responsesA. Scheffold
Memory B cell sub-populationsJ.C. Weill
Innate immune response to pneumococcalpneumoniaS. Knapp
Innate Immunity in regulation of antibodymediated inflammationR.E. Schmidt
Plasma cell memoryA. Radbruch
19.30 Departure with buses to the Viennese “Heuriger” Fuhrgassl-Huber
20Scientific Programme – Saturday, September 6, 2008
Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3
08.45-
10.00
Parallel Symposium 1:AutoimmunityChair: J. Smolen, H. Schulze-Koops
Parallel Symposium 1:InflammationChair: J. Stöckl, K. Pfeffer
Parallel Symposium 1:AllergyChair: R. Valenta, J. Kalden
The life history of an autoimmune drivercloneE. Sercarz
Mechanisms of inflammatory bone destructionK. Redlich
Human Th17 cellsS. Romagnani
Immunopathogenesis of rheumatoid arthri-tis: induction of arthritogenic autoimmunereactions by proinflammatory stimuliG. Steiner
Novel cytokines in inflammatory diseasesF. Liew
New facets in mast cell activationS. Bulfone-Paus
Modeling multiple sclerosis: autoimmune T and B cells in the pathogenesis of thebrain inflammatory diseaseH. Wekerle
IL-17 and kynurenines in pathogenic inflammationL. Romani
From allergens to vaccinesR. Valenta
10.00-
10.30Coffee Break / Exhibition
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21Scientific Programme – Saturday, September 6, 2008
Time Lecture Hall 2 Lecture Hall 3 Lecture Hall 4 Lecture Hall 5
10.30-
12.15
Autoimmunity IIChair: R. Schwinzer, G. Staffler
Infection IIChair: V. Leksa, O. Sharif
Complement SystemChair: M. Kirschfink, M. Wahrmann
Cytokines, Chemokines &their receptorsChair: U. Höpken, M. Sibilia
160. CCR7 is essential for reg-ulatory T cell function in anti-GBM glomerulonephritisK. Hochegger, A. Rosenkranz,A. Rot
168. Immunemodulation bySiglec-E during Trypanosomacruzi infectionH. Erdmann, P. R. Crocker, B. Fleischer, T. Jacobs
176. Human factor H-relatedprotein 4 (CFHR4) recruits C-reactive protein to the surfaceof necrotic cellsM. Mihlan, M. Hebecker, M. Huber-Lang, R. Dahse, P. F. Zipfel, M. Józsi
183. gp130 onmacrophages/neutrophils neg-atively regulates Th17 develop-ment during experimentaltuberculosisJ. Sodenkamp, I. Foerster, W. Mueller, C. Hoelscher
161. The nuclear receptorPPARgamma serves as an in-trinsic regulator of Th17 cell dif-ferentiationL. Klotz,, I. Dani, S. Burgdorf,A. Waisman, G. Eberl, J. Alferink, B. Langhans, T. Klockgether, P. Knolle
169. A novel Leishmania majoramastigote culture systemU. A. Wenzel, S. Möller, M. Klinger, S. Liebau, T. Laskay,G. van Zandbergen
177. Regulation of mouse fi-colin-B expression in immunecompetent cellsV. L. Runza, J. Kürchner, D. Weber-Steffens, D. N. Männel
184. The role of optineurin(FIP2) in adenovirus E3-14.7K-mediated inhibition of TNFR1apoptosisL. Klingseisen, G. Knoll, W. Schneider-Brachert
162. Spontaneous CD8+ T CellMediated Liver Inflammation ina Transgenic Mouse Model ofAutoimmune HepatitisM. Zierden, E. Kühnen, M. Odenthal, H. P. Dienes
170. The elimination ofAnaplasma phagocytophilum invivo requires CD4+ T cells, butis independent of Th1 cy-tokines and a wide spectrum ofeffector mechanismsK. Birkner, Y. Kern, B. Steiner,C. Bogdan, F. D. von Loewenich
178. Functional analyses indi-cate pathogenic role of factor H autoantibodies in atypicalhemolytic uremic syndromeS. Strobel, P. F. Hoyer, C. J. Mache, E. Sulyok, P. F. Zipfel, M. Józsi
185. Overlapping functions ofIL-7 and TSLP in lymphoid de-velopmentD. Finke, L. Flueck, A. G. Farr,A. G. Rolink, S. Chappaz
163. Peripheral T cells are thetherapeutic targets of high-dose glucocorticoids in experi-mental autoimmuneencephalomyelitisS. Wüst, J. van den Brandt, J. P. Tuckermann, R. Gold, H. M. Reichardt, F. Lühder
171. Oxidized phospholipids in-hibit phagocytosis via a PKAdependent mechanismU. Matt, O. Sharif, T. Furtner, K. Stich, A. Zivkovic, S. Knapp
179. A dual role of the C5a re-ceptor (C5aR) in acute andchronic dextran sulphate in-duced models of inflammatorybowel diseaseK. Johswich, M. Martin, A. Bleich, M. Kracht, O. Dittrich-Breiholz, E. Gessner,S. Suerbaum, C. Rheinheimer,A. Klos
186. Organ-specific suppres-sion of CCL17 productionthrough Interferon-T. Globisch, S. Stutte, V. Lukacs-Kornek, C. Kurts, I. Förster
164. The proteasome inhibitorbortezomib depletes plasmacells and protects lupus micefrom nephritisK. Neubert, S. Meister, K. Moser, F. Weisel, D. Maseda,K. Amann, T. H. Winkler, J. R. Kalden, R. E. Voll
172. Control of Persistent HBVInfection by Hepatitis B CoreAntigen-activated NK cells: A Possible Mechanism for theHBV PersistenceL. Huang, P. Chen, P. Knolle
180. Candida albicans CaHGT1and its role in complement inhi-bition and modulation of othervirulence factorsI. Lesiak, G. Vogl, T. Schwarzmüller, M. P. Dierich,K. Kuchler, R. Würzner
187. Down-regulation of IFN-during HPV-induced carcino-genesisB. Rincon-Orozco, F. Rösl
165. CD8 T cells specific for aglomerular antigen induce renalinflammation in a CD4 help de-pendent fashion and maycause progressing Glomeru-lonephritisF. Heymann, E. E. Hamilton-Williams, I. Ludwig-Portugall, S. Quaggin, J. Flöge, H. Gröne,C. Kurts
173. Acute infection with a sin-gle hepatitis C virus strain indialysis patients: analysis ofadaptive immune response andits impact on viral sequenceevolutionL. Weseslindtner, C. Neumann-Haefelin, S. Viazov,A. Haberstroh, J. Kletzmayr, J. H. Aberle, J. Timm, S. R. Ross, R. Klauser-Braun, T. F. Baumert, M. Roggendorf, R. Thimme, H. Holzmann
P419. Characterization of factorH binding to neutrophil granu-locytesJ. Losse, P.F. Zipfel, M. Józsi
188. An IFN reporter mousemodel for the visualization ofthe initiation of the Type I inter-feron response in vivoP. Dresing, S. Scheu, R. M. Locksley
166. A new model for inflam-matory bowel disease: A trans-genic mouse expressing acrossreactive T cell receptorrecognizing murine and bacter-ial HSP60N. Schmidt, T. Joeris, U. Steinhoff
174. Type I Interferons as viru-lence-determining factors inListeria monocytogenes infec-tionsB. Reutterer, S. Stockinger, A. Pilz, D. Soulat, R. Kastner, S. Westermayer, T. Rülicke, M. Müller, T. Decker
182. Rituximab-induced ADCCof tumour cells is variably modified by complement iC3bA. Dörr, C. Watzl, M. Kirschfink
189. Chemokine receptor CCR7contributes to a rapid and effi-cient clearance of lytic MHV-68from the lung while bronchus-associated lymphoid tissue har-bors virus during latencyJ. R. Kocks, H. Adler, H. Danzer, K. Hoffmann, D. Jonigk, U. Lehmann, R. Förster
167. NAADP/Ca2+ signaling: anew therapeutic target for T cellmediated autoimmune diseaseF. Odoardi, C. Cordiglieri, W. Dammermann, B. Zhang, M. Hohenegger, B. V. Potter, A. Guse, A. Flügel
126. Yersinia enterocolitica dif-ferently affects DC subpopula-tions in vivoS. E. Autenrieth, T. Linzer, P. Warnke, S. Schmitz, I. B. Autenrieth
190. IL-27 acts as a PrimingSignal on Human Keratinocytesand Antigen- Presenting CellsJ. Zeitvogel, T. Werfel, M. Wittmann
Venue
International Congress Center Berlin (ICC Berlin)
Neue Kantstraße / Ecke Messedamm
14057 Berlin, Germany
www.icc-berlin.de
Under the auspices of EFIS
Congress President
Prof. Dr. med. Reinhold E. Schmidt
Medizinische Hochschule Hannover
Klinik für Immunologie und Rheumatologie
Carl-Neuberg-Straße 1
30625 Hannover, Germany
Phone: +49 (0)511– 532-6656
Fax: +49 (0)511– 532-9067
E-Mail: [email protected]
Congress Secretariat
K.I.T. GmbH Association & Conference
Management Group & Co. KG
Kurfürstendamm 71
10709 Berlin, Germany
Phone: +49 (0)30 – 246 03-0
Fax: +49 (0)30 – 246 03-200
E-Mail: [email protected]
www.kit-group.org
2nd European Congress of Immunology
www.eci-berlin2009.com
September 13 – 16, 2009Berlin, Germany
Immunity for LifeImmunology for Health
8575_kit_eci09_anzA4_bl.indd 1 04.08.2008 11:27:59 Uhr
23Scientific Programme – Saturday, September 6, 2008
Time Lecture Hall 1
10.30-
12.45
Satellite Lunch Symposium - PhadiaVom rekombinanten Allergen zu neuen AllergietherapienChair: R. Valenta, N. Reider
Rekombinante Allergene: Vom Beginn zur GegenwartH. Breiteneder
Rekombinante NahrungsmittelallergeneK. Hoffmann-Sommergruber
Klinische Anwendungen für rekombinante AllergeneP. Schmid-Grendelmeier
Klinische Erfahrungen mit AllergenchipsJ. M. Baron
Die Komplexitaet von zellulären Allergietesten J. Kleine-Tebbe
Immuntherapie und Verlaufkontrolle mit rekombinanten AllergenenG. Pauli
12.45-
13.00Pause (mit Snack)
Time Lecture Hall 1
13.00-
13.45
Klinische Fälle aus der Allergologie: Wie hätten Sie entschieden?Chair: Z. Szepfalusi, G. Pauli
Werner Aberer, Reinhart Jarisch, Felix Wantke und Stefan Wöhrl präsentieren klinische Fälle aus der Allergologie
14.00-
14.30
Best Poster AwardsChair: J. Smolen, S. Meuer
Time Lecture Hall 2
15.00 General Assembly ÖGAIChair: J. Smolen, M. Säemann
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Poster Viewing 25
Thursday, September 4, 2008
09.30 – 10.30 hrs
T-Lymphocytes IChair: B. Jahn-Schmid, C. ScheineckerP001 – P028
T-Lymphocytes IIChair: W. Pickl, H. StockingerP029 – P056
Innate Immunity: Antigen-Presenting CellsChair: T. Weichhart, M. GillietP057 - P075
Signal TransductionChair: L.J. Berg, W. EllmeierP076 - P094
Tumor ImmunologyChair: O.J. Finn, T. BlankensteinP095 - P117
Thursday, September 4, 2008
15.30 – 16.30 hrs
Innate Immunity: RegulationChair: M. Zeyda, S. BeissertP118 - P134
Pattern Recognition Receptors & Myeloid CellsChair: F. Schmitz, J. StöcklP135 - P151
NK CellsChair: C. Watzl, V. SexlP152 - P164
Vaccines & AdjuvantsChair: H. Lassmann, T. WeichhartP165 - P187
ImmunomodulationChair: M. Fischer, G. ZlabingerP188 - P208
Friday, September 5, 2008
09.30 – 10.30 hrs
Alloimmunity & ToleranceChair: G. Böhmig, M. SäemannP209 - P233
AllergyChair: B. Bohle, S. Bulfone-PausP234 - P264
InfectionChair: U. Schaible, S. KnappP265 - P296
Mucosal ImmunityChair: S. Meuer, P. BrandtzaegP297 - P308
Friday, September 5, 2008
15.30 – 16.30 hrs
Autoimmunity IChair: R. Germain, E. SercarzP309 - P329
Autoimmunity IIChair: G. Steiner, J. KaldenP330 - P352
Complement System and B-LymphocytesChair: F. Melchers, A. RadbruchP420 and P353 - P360
Regulatory LymphocytesChair: L. Klein, R. BacchettaP361 - P383
Cytokines, Chemokines & their receptorsChair: F.Y. Liew, L. RomaniP384 - P404
Veterinary ImmunologyChair: B. Kaspers, A. SaalmüllerP405 - P418
Business MeetingsAs per date of printing
Closed Business Meetings
Wednesday, September 3, 200810.00 – 12.00 hrs Steering Committee Meeting ECI 2009 Lecture Room 25 / Level 812.00 – 14.30 hrs Vorstandssitzung DGfI Hotel Regina – Salon Makart
Thursday, September 4, 200811.00 – 13.00 hrs Promotion Committee Meeting des ECI 2009 Lecture Room 25 / Level 812.30 – 14.00 hrs Sitzung der DGfI Kommission “Fachimmunologe” Lecture Room 13 / Level 7
Friday, September 5, 200812.00 – 14.00 hrs Arbeitskreise der DGfI Lecture Room 25 / Level 8
Saturday, September 6, 200809.00 – 11.00 hrs DGfI Educational Committee Lecture Room 25 / Level 8
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Satellite Lunch Symposia
Thursday, September 4, 2008, 12.15 – 13.45 hrs, Lecture Hall 1
B cell: Promising target in autoimmune diseasesChair: J. Smolen
The biology of the B cell in autoimmune diseasesA. Radbruch
Clinical experiences with B cell therapiesT. Dörner
Safety: Experiences with RituximabH-P. Brezinsek
Friday, September 5, 2008, 12.15 – 13.45 hrs, Lecture Hall 2
Immune modulation with intravenous immunoglobulin: the established and the advancesChair: S. Meuer
IntroductionS. Meuer
Immunthrombocytopenia as the first model for biological treatment with IVIG in chronic inflammatory and autoimmune diseasesP. Imbach
Intravenous Immunoglobulins: mechanisms of action and options for improvement of therapeutic efficacyF. Nimmerjahn
Basic research in human immunology creates new therapeutic optionsS. Meuer
Discussion and wrap-up
Saturday, September 6, 2008, 10.30 – 12.45 hrs, Lecture Hall 1
Vom rekombinanten Allergen zu neuen AllergietherapienChairs: R. Valenta, N. Reider
Rekombinante Allergene: Vom Beginn zur GegenwartH. Breiteneder
Rekombinante NahrungsmittelallergeneK. Hoffmann-Sommergruber
Klinische Anwendungen für rekombinante AllergeneP. Schmid-Grendelmeier
Klinische Erfahrungen mit AllergenchipsJ.M. Baron
Die Komplexitaet von zellulaeren AllergietestenJ. Kleine-Tebbe
Immuntherapie und Verlaufkontrolle mit rekombinanten AllergenenG. Pauli
12.45 - 13.00 Pause (mit Snack)
13.00 - 13.45 Klinische Fälle aus der Allergologie: „Wie hätten Sie entschieden”
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Information on Posters
Poster TopicsP01 T-Lymphocytes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P001 – P056P02 Innate Immunity: Antigen-Presenting Cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P057 – P075P03 Signal Transduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P076 – P094P04 Tumor Immunology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P095 – P117P05 Innate Immunity: Regulation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P118 – P134P06 Pattern Recognition Receptors & Myeloid Cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P135 – P151P07 NK cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P152 – P164P08 Vaccines & Adjuvants . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P165 – P187P09 Immunomodulation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P188 – P208P10 Alloimmunity & Tolerance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P209 – P233P11 Allergy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P234 – P264P12 Infection . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P265 – P296P13 Mucosal Immunity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P297 – P308P14 Autoimmunity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P309 – P352P15 B-Lymphocytes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P353 – P360P16 Regulatory Lymphocytes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P361 – P383P17 Cytokines, Chemokines & their receptors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P384 – P404P18 Veterinary Immunology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P405 – P418P19 Complement system . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P420 – P420
• Posters will be on display from Wednesday, September 3, (15.00 hrs) to Saturday, September 6, 2008,(15.00 hrs).
• Poster mounting will be possible on: Wednesday, September 3, 2008 from 10:00 - 15:00.
• Removal will be possible on: Saturday, September 6, 2008 from 14:30 - 15:30.Please note that posters not removed by then, will be taken down by conference staff and will not be stored or forwarded to the authors after the meeting.
• You will find your poster board number in the author index at the end of the abstract book.
Presence at PostersIn order to enable discussion and interaction with other participants, we request you or another member of yourgroup to be at your poster board at the following times:
• Thursday, September 4, 2008, 09.30 – 10.30 hrsT-Lymphocytes-1 P001 - P028T-Lymphocytes-2 P029 - P056Innate Immunity: Antigen-Presenting Cells P057 - P075Signal Transduction P076 - P094Tumor Immunology P095 - P117
• Thursday, September 4, 2008, 15.30 – 16.30 hrsInnate Immunity: Regulation P118 - P134Pattern Recognition Receptors & Myeloid Cells P135 - P151NK Cells P152 - P164Vaccines & Adjuvants P165 - P187Immunomodulation P188 - P208
• Friday, September 5, 2008, 09.30 – 10.30 hrsAlloimmunity & Tolerance P209 - P233Allergy P234 - P264Infection P265 - P296Mucosal Immunity P297 - P308
• Friday, September 5, 2008 15.30 – 16.30 hrsAutoimmunity-1 P309 - P329Autoimmunity-2 P330 - P352B-Lymphocytes P353 - P360Regulatory Lymphocytes P361 - P383Cytokines, Chemokines & their receptors P384 - P404Veterinary Immunology P405 - P418Complement System P420
If this is not possible, please leave a note on your poster board detailing the times when you will be present at the board.
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Information for Speakers
Projection and Technical Setting• All rooms will be equipped with data- and overhead projection (no slides).• It is essential that you load and view your presentation in the slide preview room preferably in the
morning of the day your talk is scheduled, but no later than 2 hours in advance.• The lecture rooms are exclusively equipped with Windows-PCs (no Macintosh machines). In case you
absolutely need to use your own laptop or notebook, please contact the preview center well in advance of your talk.
• Please bring a USB-stick or CD-ROM, all formatted for Windows® (PC). You may want to carry a second disk/CD as a back-up in case there is any unsolvable technical problem.
• File Format: Microsoft® Power Point™ presentation formatted for Windows® (PC) only. (Operatingsystem: Windows XP®)
• Preferred Resolution: XGA (1024 x 768 pixel)
Preview RoomThe Speaker’s Preview will be located in Room Nr. 11 on Level 7. Equipment for a final check of the sequence of yourpresentation is available in the preview room. All presenters should bring their electronic presentation to the previewroom preferably in the morning of the day of the talk, but no later than 2 hours before the start of the session. Forsessions starting at 08.15 hrs, the PowerPoint presentations should be handed in the previous day.Opening hours of the preview room:Wednesday, September 3, 2008 12.00 – 18.00Thursday, September 4, 2008 07.30 – 18.00Friday, September 5, 2008 07.30 – 18.00Saturday, September 6, 2008 08.15 – 15.00
Programme ChangesThe organisers cannot assume any liability for changes in the programme due to external or unforeseen circumstances.
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Congress Information
Abstract BooksYou will find an Abstract Book in your conference bag.
Accreditation
The Joint Annual Meeting of Immunology has applied for credits at the European Accreditation Council for Con-tinuing Medical Education, Institution of the UEMS.The number of credits (which will be announced after the meeting) will figure on the respective confirmation,which will also be sent after the meeting.The rules of the EACCME state that participants are kindly asked to fill in the feedback (evaluation) form includedin the conference bag. It can be returned to the registration desk.
Participants applying for EACCME Credits will have to have their badge scanned daily at the registrationdesk before entering the conference. The confirmation will be mailed after the conference at the end ofSeptember.
Die österreichische Akademie der Ärzte hat an diese Veranstaltung 41 Diplomfortbildungspunktevergeben.
Admission to Lecture HallsParticipants are requested to enter the lecture halls via Level 8 only.
BadgesParticipants will receive their name badges from the conference registration desk. Since only registered participants will be per-mitted to attend scientific sessions, the exhibition and poster areas, you are kindly asked to wear your badge when entering thecongress venue. Please note that admission to scientific sessions is strictly restricted to participants wearing their badges. Ex-hibitors and accompanying persons are not entitled to attend the scientific sessions. Lost badges can be replaced at the regis-tration desk. However, a handling fee of € 20,- will be charged.
The following badge-colours are used at the Congress:
White � ParticipantsYellow � Accompanying PersonsGreen � ExhibitorsRed � Staff
Cancellations and RefundsNotice of cancellation must be made in writing by registered letter or fax to the Congress Office.The policy for refunding registration fees is as follows:Written cancellation received:- before July 31, 2008: 75% refund - after July 31, 2008: no refundThe date of the postmark or fax ID is the basis for considering refunds. Refunds will be made after the congress.
Cash BarSnacks and drinks may be purchased at the cash bar on Level 8 during congress hours.
Certificate of AttendanceConfirmations of attendance will be issued at the registration desk.
City TourThe city tour “Classical Vienna – A City Stroll” will take place on Thursday, September 4, 2008. It is free of charge for accompa-nying persons, however, registration in advance is mandatory.
Coffee BreaksDuring the session breaks, refreshments will be served free of charge to participants wearing name badges.
Exhibition Opening HoursWednesday, September 3, 2008 15.00 – 17.00 hrsThursday, September 4, 2008 08.15 – 17.00 hrsFriday, September 5, 2008 08.15 – 17.00 hrsSaturday, September 6, 2008 08.45 – 15.00 hrs
Hotel and Tours DeskMondial, the official travel agency of the meeting, will be present at the conference onWednesday, September 3, 2008 from 14.30 – 17.30 hrs and onThursday, September 4, 2008 from 07.30 – 09.30 hrs.If you have any questions regarding your hotel booking or the city tour, please approach Mondial. They will be located near theregistration desk.
InternetA few internet stations will be available at the conference. Please ask at the registration desk. You may also find small internetcafés throughout the city.
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Congress Information
Message BoardA Message Board and notice of the daily programme are available on Level 7 and Level 8.
Poster Mounting and RemovalThere are four poster sessions: Thursday and Friday from 09.30 – 10.30 hrs and from 15.30 – 16.30 hrs. Poster mounting will bepossible on Wednesday, September 3, 2008 from 10.00 – 15.00 hrs. Poster removal will be possible on Saturday, September 6,2008 from 14.30 – 15.30 hrs. Please note that the organisers cannot assume any liability for loss or damage of posters displayedin the poster area. Posters that are not removed by 15.30 hrs on Saturday, September 6, 2008 will be removed by staff and willnot be stored or forwarded to the author after the meeting.
Preview RoomThe Speaker’s Preview will be located in Room Nr. 11 on Level 7. Equipment for a final check of the sequence of your presenta-tion is available in the preview room. All presenters should bring their electronic presentation to the preview room preferably inthe morning of the day of the talk, but not later than 2 hours before the start of the session. For sessions starting at 08.15 hrs,the PowerPoint presentations should be handed in the previous day.Following are the opening hours of the preview room:Wednesday, September 3, 2008 12.00 – 18.00Thursday, September 4, 2008 07.30 – 18.00Friday, September 5, 2008 07.30 – 18.00Saturday, September 6, 2008 08.15 – 15.00
Public TransportRegistered congress participants receive a 4-days-ticket when picking up their registration materials. This ticket is valid for all pub-lic transport within Vienna from Wednesday, September 3, 2008 to Saturday, September 6, 2008. This ticket is not valid for goingto the airport, since the airport is out of town. Congress participants are kindly requested to return their ticket if it is not needed.
Registration Desk opening hoursWednesday, September 3, 2008 10.00 – 18.00Thursday, September 4, 2008 07.30 – 18.00Friday, September 5, 2008 07.30 – 18.00Saturday, September 6, 2008 08.15 – 15.00
Smoking PolicyThe Joint Annual Meeting of Immunology is a “No-smoking-Conference”. Please note that smoking is banned from all publicbuildings. Restaurants and bars may, depending on size, be declared either as “smoking” or “no-smoking” locations or haveseparate areas and ventilation systems.
StaffShould you have any questions, congress staff, recognizable by a blue t-shirt and red badge, will be pleased to help you.
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Registration Fees
Onsite registration
Wednesday, September 3, 2008 10.00 – 18.00Thursday, September 4, 2008 07.30 – 18.00Friday, September 5, 2008 07.30 – 18.00Saturday, September 6, 2008 08.15 – 15.00
What is covered by the registration fee?
Payment of registration fees may be made in cash (Euros only), by maestro debit card, or by the following credit cards: Diners Club, Mastercard, Visa.
Please note that the reduced registration fee is only applicable if it has been credited to the congress account before the dead-line. Registering without performing an actual payment is not sufficient to benefit from the reduction. Pre-registration withoutpayment of the registration fee is possible. The full fee is to be paid at the registration desk.
Cancellations and refunds:
Notice of cancellation must be made in writing by registered letter or fax to the Congress Office.
Notice of cancellation must be made in writing by registered letter or fax to the Congress Office.The policy for refunding registration fees is as follows:Written cancellation received:- before July 31, 2008: 75% refund - after July 31, 2008: no refundThe date of the postmark or fax ID is the basis for considering refunds. Refunds will be made after the congress.
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Payment received before June 15, 2008 after June 15, 2008 and on-site
Members EUR 190.— EUR 300.—
Student Members* EUR 95.— EUR 135.—
Non-Members EUR 280.— EUR 390.—
Student Non-Members* EUR 140.— EUR 180.—
Accompanying Persons EUR 60.— EUR 60.—
Day Ticktet Member EUR 140,—
Day Ticket Non-Member EUR 180,—
* please provide a copy of an ID together with your registration
Participants Accompanying persons
• Admission to all scientific sessions• Access to the exhibition • Coffee breaks• Welcome reception at the City Hall
Thursday, September 4, 2008, 19.00 hrs• Abstract book• Programme• 4-days public transport ticket
• Admission to the welcome reception at the City HallThursday, September 4, 2008, 19.00 hrs
• Classical Vienna City Tour*,Thursday, September 4, 2008, 09.00 hrs
• Access to the exhibition and coffee breaks
(no admission to lectures)
*Please note that the classical city tour is not available foron site registrations of accompanying persons.
General Information
Bank services - Money mattersBanks are open from 8.30 – 12:30 and from 13:30 – 15:00, Monday to Friday. Some banks are also open on Thursday afternoonsuntil 17:30 hrs. Cash machines (ATMs), which accept all major international bank cards, are available throughout the city. Thereis a cash machine in the main entrance of the Vienna General Hospital. The currency of Austria is the Euro (€). Major credit cardsare widely accepted, but please always check beforehand.
Car ParkingThe Vienna General Hospital has approximately 800 car parking spaces available for visitors in an underground car park. Theentrance is at Währinger Gürtel.
Eating out in Vienna Vienna has a broad variety of local and international restaurants, many of them located in the old city and in the vicinity of the con-ference venue.
Emergency servicesThe phone number to dial for emergencies is 112.
GSM cell phone roaming GSM cell/mobile phone roaming is available without any problems for all major international providers. It is advisable to inquirebeforehand at your provider which roaming company in Austria offers the cheapest tariffs.
InsuranceIn registering for the Joint Annual Meeting of Immunology 2008 participants agree that neither the organising committee northe congress office assume any liability whatsoever. Participants are requested to make their own arrangements for health andtravel insurance.
Internet and printing facilitiesA few internet stations will be available at the conference. Please ask at the registration desk. You may also find small internetcafés throughout the city.
LanguageThe official language of the congress will be English (no simultaneous translation).
Medical careThe Austrian National Health Service may be used by all persons from European Union countries who have the E111 Form (EHI-Card). This form/card should be obtained at the health service or post office of the visitor’s home country before travelling toAustria. It is advisable for participants from countries outside the European Union to take out medical insurance before reachingAustria, since they will be charged for access to the national health system.
PharmaciesMedicines that do not require a medical prescription may be purchased over the counter. If you need advice, do not hesitate toask the pharmacist. If you usually take medication, it is advisable to bring a sufficient amount with you for your trip. Pharmaciesin the vicinity of the conference venue are on Zimmermannplatz 1, 1090 Vienna. There are duty pharmacies open 24 hours a day.Outside each pharmacy there is a list of the nearest duty pharmacies, or you may ask at your hotel reception for more informa-tion.
Safety - CrimeVisitor safety is generally adequate. Like in any other major European city, you can walk everywhere using common sense. Pickpocketing in heavily visited tourist zones or in public transport lines might be a concern. Unfortunately experience has shown that some basic precautionary measures should always be kept in mind in any city:- Do not carry important items like flight tickets, passports etc. with you when visiting the conference or strolling through the city;leave them in the hotel safe during your stay. Rather carry a photocopy of your passport or an identity card with you.- Try not to carry all documents, money, credit cards and other essential items and valuables in one bag. If it gets lost or stolen,everything will be gone and might be difficult to replace on short notice, especially passports and visa to return to your countryof residence. - Take off your name badge when leaving the conference centre.
ShopsShops in Vienna are generally open between 09.00 and 18.00 hrs Mon-Fri, and between 09.00 and 12.00 on Saturdays. Someshops are open until 19.00 Mon-Fri and until 17.00 on Saturdays. Shops are usually closed on Sundays, except for a few estab-lishments with special permits.
TaxisThere are Taxi ranks throughout the city, but calling is often your best option. Please address your hotel reception or the regis-tration desk of the conference venue. A taxi station can be found in front of the main entrance at Level 5 and at Lazarettgasse(exit on Level 4).
TippingTips are not obligatory in Austria, although people usually tip approximately 10% at restaurants, cafés and bars. Hotel and air-port porters will accept tips, depending on the luggage.
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General Information
Travelling within Vienna
Registered congress participants receive a 4-days-ticket when picking up their registration materials. This ticket is valid for all pub-lic transport within Vienna from Wednesday, September 3, 2008 to Saturday, September 6, 2008. This ticket is not valid for goingto the airport, since it is out of town. Congress participants are kindly requested to return their ticket if it is not needed.
For accompanying persons and exhibitors tickets are available from machines at underground stations (maestro debit cards ac-cepted), at news agents’, or at Vienna Transport Authority’s ticket offices. Tickets bought in advance are cheaper and must bepunched in a blue ticket cancelling machine on the tram or bus, or at the barrier before boarding the underground train.
Single trip tickets can be used for any single trip within Vienna. You may change lines (and switch between bus, tram, under-ground, or urban train), but you may not interrupt your journey. Ticket price: EUR 1.70 when bought in advance; EUR 2.20 whenbought in the means of transport.The 24-hour pass is valid throughout Vienna for exactly 24 hours from the time it is punched. Price: EUR 5.70The 72-hour pass is valid throughout Vienna for exactly 72 hours from the time it is punched. Price: EUR 13.60The 8-day ticket is valid for any eight days, not necessarily eight consecutive days. It is a rover ticket, which means you can travelall around Vienna. You can also use the ticket for several people travelling together. Simply punch one strip for each person in thegroup. Price: EUR 27.20Week-pass valid from Monday to Monday, 09.00 hrs. Price: EUR 14.00
A taxi is the most comfortable way of getting around the city but also the most expensive. They are identifiable by their roof-signwhich is lit when available. Prices must be displayed inside the cab and meters (which are compulsory in all cabs) will indicatethe fare.
Travelling from and to the Airport
Vienna International Airport is located 13 kilometres south east of Vienna.
City Airport Train (CAT)The train service between the airport and the city centre (City Air Terminal – Station ‘Wien Mitte’) is every 30 minutes and takes16 minutes. It is covered from 6:05 hrs to 00:05 hrs (Airport to City) and from 5:38 hrs to 23:38 hrs (City to Airport). Tickets maybe purchased online (EUR 8.00 single or EUR 15.00 return), from ticket machines at the airport/station (EUR 9.00 single or EUR16.00 return) or on board (EUR 10.00 single). From ‘Wien Mitte’ you can take the green line (U4) direction Heiligenstadt and getoff at ‘Spittelau’ (five stops) and then take the brown line (U6) direction Siebenhirten and get off at Michelbeuern-AllgemeinesKrankenhaus.
Taxi fares to the conference venue are about EUR 35.00 and take around 25 minutes. There is a taxi rank outside the airport ter-minal. Night-time fees are slightly higher.
Travelling to the Vienna General Hospital by Public TransportationThe Vienna General Hospital (the congress venue) is easily reachable by taking the subway line U6 (the brown line) and gettingoff at Michelbeuern – Allgemeines Krankenhaus. Furthermore, it can be reached by tramway 42, tramways 5 and 33 (stopLazarettgasse) as well as tramways 43 and 44 (stop Alser Straße).
ViennaVienna, the capital of Austria, 2 million inhabitants, is situated on the banks of the Danube. Vienna is a dream city for anyone withan interest in history. Narrow, medieval alleyways and grand boulevards lead to historic sights such as the Imperial Palace (Hof-burg), Belvedere Palace, Burgtheater, the Spanish Riding School, St. Stephen’s Cathedral, the Opera House, Karlskirche, orSchönbrunn Palace. Vienna has been synonymous with music for centuries, and was home to Mozart, Beethoven, Schubert andJohann Strauss. The Vienna Philharmonic Orchestra is one of the world’s top orchestras; the Vienna Boys’ Choir is triumphantlysuccessful wherever it tours. Vienna possesses a lively and vast array of cultural attractions, from classical or experimental the-atre, film or dance festivals, opera or operetta, to exhibitions and concerts. The Museum of Fine Arts is one of the world’s largestand most distinguished museums, housing priceless works of art. Art accompanies you wherever you go in Vienna - even someof its underground stations are listed properties on account of their elegant, ornamental Jugendstil (Art Nouveau) style designedby Otto Wagner. For more information about Vienna, please see www.aboutvienna.org.
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Venue
Location of the Vienna General Hospital and the Lecture Centre
Public transportation in ViennaThe Vienna General Hospital (the congress venue) is easily reachable by taking the subway line U6 and getting offat the station ”Michelbeuern – Allgemeines Krankenhaus”. Furthermore it can be reached with the tramway 42, thetramway 5 and 33 (station ”Lazarettgasse”) as well as the tramways 43 and 44 (station ”Alser Strasse”)
35
GENERAL INFORMATIONCongress venueVienna General HospitalAllgemeines Krankenhaus WienLecture Hall CentreHörsaalzentrumWähringer Gürtel 18-20A-1090 Vienna, Austria
HÖRSAALZENTRUM
EBENE 07/08
Venue 36
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LectureHall 1
LectureHall 3
LectureHall 2
LectureHall 5
LectureHall 4
Escalators to main entranceGreen Elevators to main entrance
Red Elevators
PreviewRoom
Registration
MeetingRoom 13
Coffee
Cof
fee
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Exhibition
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Cloak-room
Level 7Access from main entrance
No entrance to Lecture Halls.Please use the doors on Level 8.
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LectureHall 1
LectureHall 3
LectureHall 2
LectureHall 5
LectureHall 4
Escalators to main entranceGreen Elevators to main entrance Red Elevators
MeetingRoom
25
Posters
Posters
Posters and Exhibition
sretsoPraB hsa
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Coffee
Level 8Access to Lecture Halls
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?
? Entrance to Lecture Halls
Posters
Post
ers
Social Events
Thursday, September 4, 2008, 19.00 hrs
Welcome Reception by the Mayor of Vienna at the Vienna City Hall
The mayor of the city of Vienna is pleased to invite you to a Welcome Reception. Meet your colleagues at this event. Enjoy theevening with a Buffet and live music.
Dress code: business attire
Attendance is free for registered participants and accompanying persons. Those who have registered prior to the congressshould have received their ticket with the congress material. Please remember to bring your ticket.
Please note that attendance is limited and advance registration is mandatory in order to receive a ticket!A limited number of tickets will still be available for onsite bookings.
Venue: Vienna City Hall, Lichtenfelsgasse 2, 1010 Vienna
Directions: From the conference venue take the brown underground line U6 (direction Siebenhirten) one stop and get off at AlserStrasse. Take the tram 43 (direction Schottentor) and get off at Landesgerichtsstrasse. From there you can walk along Landes-gerichtsstrasse until you reach the city hall on your left hand side. Walk past the city hall and turn left into Lichtenfelsgasse. Theentrance to the reception is on your left.
Alternatively you can take the brown underground line U6 (direction ‘Floridsdorf’) three stops and get off at ‘Spittelau’. Take thegreen underground line U4 (direction ‘Hütteldorf’) three stops and get off at ‘Schottenring’. Take the purple underground line U2(direction ‘Karlsplatz’) two stops and get off at ‘Rathaus’. Take the exit towards the front of the train and turn left and cross thestreet. This is Lichtenfelsgasse. The entrance to the Reception is on the left hand side.
Friday, September 5, 2008, 19.30 hrs.
Dinner at a Viennese “Heuriger”
An evening spent in typical Austrian wine taverns in Vienna. You will be served a delicious Austrian buffet and excellent localwines while enjoying the atmosphere of a traditionally decorated restaurant. “Heuriger” could be translated with “of this year”and means a young crisp wine produced during the current wine season. Only wine producers serving their own product,grown in the vineyards of Vienna, may call their tavern “Heuriger”.
Dress code: casual
Venue: Weingut Fuhrgassl Huber Neustift/Walde 681190 Vienna
Buses depart from the main entrance on Level 5 of the Vienna General Hospital, at 19.30 hrs and return in the lateevening.
Price per ticket including transport, music, food and beverages: EUR 45.–
Please note that advance registration is mandatory in order to receive a ticket! A limited number of tickets will still beavailable for onsite bookings.
37
Underground Map 38
9
Congressvenue
WelcomeReception
City Map 39
1) Lecture Centre of the ViennaGeneral Hospital (AKH)
2) City Hall (Welcome Reception)3) Arcotel Boltzmann4) Mercure Josefshof5) Hotel & Palais Strudlhof6) Carlton Opera
7) Wandl8) Atlas9) Academia10) Pension Ani Falstaff11) Pension Ani12) Regina13) Royal
Exhibition – General Information
Exhibiton Organiser:
Name MAW – Medizinische Ausstellungs- und WerbegesellschaftAddress Freyung 6
1010 Vienna, Austria
Telephone Ms. Ingrid Winkler: +43 664 441 8285Ms. May-Britt Ernst: +43 664 105 2018
Fax +43 1 535 6016E-mail [email protected]
Exhibition Dates & Opening hours:
Wednesday, September 3, 2008 15.00 – 17.00 hrsThursday, September 4, 2008 08.15 – 17.00 hrsFriday, September 5, 2008 08.15 – 17.00 hrsSaturday, September 6, 2008 08.45 – 15.00 hrs
Poster Mounting, Poster Viewing, Poster Removal Hours
Wednesday, September 3, 2008 – poster mounting 10.00 – 15.00 hrsWednesday, September 3, 2008 – poster viewing 15.00 – 18.00 hrsThursday, September 4, 2008 – poster viewing 08.15 – 18.00 hrsFriday, September 5, 2008 – poster viewing 08.15 – 18.00 hrsSaturday, September 6, 2008 – poster viewing 08.45 – 14.30 hrsSaturday, September 6, 2008 – poster removal 14.30 – 15.30 hrs
Location
Venue Lecture Centre of the Vienna General HospitalExhibition Areas Level 7 and Level 8Address Währinger Gürtel 18-20, 1090 Vienna, Austria
40
List of Sponsors, Exhibitors and Advertisers*
Ärztezentrale Adressen- und Drucksortenverlag, Vienna, Austria
Abd Serotec- Endeavour House, Oxon, United Kingdom
Acris Antibodies, Hiddenhausen, Germany
Active Motif Europe, Rixensart, Belgium
Aesca Pharma, Traiskirchen, Austria
Alk Abello Allergie – Service GmbH, Linz, Austria
Allergopharma, Vienna, Austria
AstraZeneca Österreich, Vienna, Austria
Becton Dickinson Austria, Schwechat, Austria
Bencard Allergie, Vienna, Austria
Bender Medsystems, Vienna, Austria
Biomedica, Vienna, Austria
Bio-Rad Laboratories, Munich, Germany
Biotest AG, Dreieich, Germany
Biozym Biotech Trading, Vienna, Austria
Boehringer Ingelheim International GmbH, Ingelheim am Rhein, Germany
CellGenix Technologie Transfer, Freiburg, Germany
Cell Kinetice, Lod, Israel
2nd European Congress of Immunology – ECI 2009
eubio, Vienna, Austria
Fermentas, St. Leon-Rot, Germany
GE Healthcare Europe, Vienna, Austria
Greiner Bio – One, Kremsmünster, Austria
Hal Allergy, Vienna, Austria
*(as per printing date)
41
List of Sponsors, Exhibitors and Advertisers*
Invitrogen, Karlsruhe, Germany
Jackson ImmunoResearch Europe Ltd., Suffolk, United Kingdom
LaVision BioTec, Bielefeld, Germany
Mabtech AB, Nacka Strand, Sweden
Ferdinand Menzl Medizintechnik, Vienna, Austria
Miltenyi Biotec, Bergisch Gladbach, Germany
NatuTec, Frankfurt am Main, Germany
New England Biolabs, Frankfurt am Main, Germany
Novartis Pharma, Vienna, Austria
Octapharma, Lachen, Switzerland
Partec, Görlitz, Germany
PeproTech, Hamburg, Germany
Phadia Austria, Vienna, Austria
Porsche Austria
ProFas, Regensburg, Germany
Charles River Consulting, Sulzfeld, Germany
Roche Austria, Vienna, Austria
R + D Systems, Wiesbaden, Germany
Siemens Medical Solutions Diagnostics, Vienna, Austria
Stallergenes France, Antony Cedex, France
Stemcell Technologies, Grenoble, France
tebu – bio, Offenbach, Germany
THP Medical Products, Vienna, Austria
Werfen Austria, Vienna, Austria
Wiley Blackwell, Weinheim, Germany
Yakult Deutschland, Neuss Germany
*(as per printing date)
42
Notes
Printed in Austria by: ROBIDRUCK, 1200 Vienna – www.robidruck.co.at
Das Immunglobulin inseiner natürlichen Form
Natur weitergeben
Zusammensetzung: 1 ml Intratect® enthält 50 mg Plasmaproteine vom Menschen, davon mind. 96 % IgG (57,2 % IgG1, 37,2 % IgG2, 3,1 % IgG3, 3,0 % IgG4). Höchstgehalt an IgA: 2 mg/ml. Hilfsstoffe: Glycin, Wasser zur Injektion. Anwendungsgebiete: Substitutionstherapie bei primären Immunmangelsyndromen, sekundärer Hypogammaglobulinämie und rezidivierenden bakteriellen Infektionen bei CLL und multiplem Myelom, Kinder mit angeborenem AIDS und rezidivierenden Infektionen. Immunmodulation bei ITP bei Kindern oder Erwachsenen mit einem hohen Blutungsrisiko oder vor chirurgischen Eingriffen zur Korrektur der Thrombozytenzahl, Guillain-Barré-Syndrom und Kawasaki-Syndrom. Allogene Knochenmarktransplantation. Art der Anwendung, Dosierung: Intratect® wird intravenös verabreicht. Dosierung und Intervalle der Infusionen richten sich nach der Indikation. Gegenanzeigen: Überempfi ndlichkeit gegen jegliche Bestandteile des Präparates. Überempfi ndlichkeit gegen homologe Immunglobuline, insbesondere in den sehr seltenen Fällen von IgA-Mangel, wenn der Patient Antikörper gegen IgA aufweist. Spezielle Hinweise: Bestimmte schwere unerwünschte Nebenwirkungen können im Zusammenhang mit der Infusionsgeschwin-digkeit stehen. Es ist die in der Gebrauchsinformation beschriebene Infusionsgeschwindigkeit zu beachten. Die Patienten müssen während der gesamten Dauer der Infusion kontrolliert und auf Symptome uner-wünschter Wirkungen beobachtet werden. Bestimmte unerwünschte Nebenwirkungen können bei einer hohen Infusionsgeschwindigkeit häufi ger auftreten, bei Patienten mit Hypo- oder Agammaglobulinämie mit oder ohne IgA-Mangel, bei Patienten, die zum ersten Mal Immunglobulin vom Menschen erhalten oder, in seltenen Fällen, bei einem Wechsel des Immunglobulin-Präparates oder nach einer längeren Behand-lungspause. Nebenwirkungen: Gelegentlich können Schüttelfrost, Kopfschmerzen, Fieber, Übelkeit und Erbrechen, allergische Reaktionen, niedriger Blutdruck, Gelenkschmerzen und leichte Rückenschmerzen. Selten: plötzlicher Blutdruckabfall, vorrübergehende Hautreaktionen, Anstieg des Serumkreatinin-Spiegels, akutes Nierenversagen, thromboembolische Komplikationen. In Einzelfällen: anaphylaktischer Schock, reversible aseptische Meningitis, reversible hämolytische Anämie/Hämolyse. Wechselwirkungen: Die Gabe von Immunglobulin kann für eine Dauer von mindestens 6 Wochen und bis zu 3 Monaten die Wirksam-keit von attenuierten Lebendimpfstoffen wie Masern-, Röteln-, Mumps- und Windpockenimpfstoffen beeinträchtigen. Nach der Gabe dieses Präparates ist vor der Impfung mit attenuierten Lebendimpfstoffen eine Wartezeit von 3 Monaten einzuhalten. Bei Masernimpfung kann diese Beeinträchtigung bis zu einem Jahr fortbestehen. Daher sollte bei Patienten, die Masernimpfstoff erhalten, der Antikörperstatus über-prüft werden. Handelsformen: Gebrauchsfertige Lösung zur intravenösen Infusion in Durchstichfl aschen aus Glas zu 20 ml (1,0 g), 50 ml (2,5 g), 100 ml (5,0 g) und 200 ml (10,0 g).
Biotest Pharma GmbH · Postfach 10 20 40 · D-63266 Dreieich · www.biotest.de
Intratect_DGN.260706.indd 1 01.08.2006 11:41:20 Uhr