January 27, 2009 4 th BVDV Symposium –BVDV Variability: Impact on Virulence, Host Range, and...
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Transcript of January 27, 2009 4 th BVDV Symposium –BVDV Variability: Impact on Virulence, Host Range, and...
January 27, 20094th BVDV Symposium –
BVDV Variability: Impact on Virulence, Host Range,
and Control
Bovine Viral Diarrhea Virus (BVDV) Research Needs and Coordinating Efforts of NCBA, AABP, AVC, and
USAHA
BVDV Research Priorities: Input NCBA BVD Research Subcommittee
2008NCBA BVD Working Group 2008Academy of Veterinary Consultants:
BVDV committeeAABP BVDV committee2008 USAHA Infectious Diseases of
Cattle Committee
BVDV Research Priorities1. Assessment of the Economic Impact of BVDV
in Beef Production Operations2. Design and Evaluation of Surveillance/Control
Programs3. Surveillance, Identification, and
Determination of Significance of Emerging BVDV Subtypes
4. Development and Critical Evaluation of Diagnostic Tests
5. Critical Evaluation of Current Vaccines6. Development of Innovative New BVDV
Vaccines7. Investigate the Pathogenesis of BVDV in
Cattle Based on Disease Predisposition and Genetics
BVDV Research PrioritiesAssessment of Economic Impact of
BVD in Beef Production Operations General economic impact of BVDTransmission dynamics of PI
(Persistently Infected) and TI (Transiently Infected) BVD cattle in production enterprises in relation to economic cost
Morbidity and mortality rate of TI and PI calves in relation to economic cost
Design and Evaluation of Surveillance Programs
Surveillance strategies for early detection of PI BVDV incursion in BVDV negative beef breeding herds and support for herd disease freedom claims
Testing strategies at the ranch, dairy, auction market or feedyard to economically detect positive individuals and herds and to control herd introduction risk
Management strategies for biosecurity and biocontainment to control impact of PI cattle
Role of wildlife as reservoir of exposure and infection for cattle
Surveillance, Identification, and Determination of Significance of
Emerging BVDV Subtypes
Detection and confirmation of new BVDV subtypes in the U.S.
Determine if differences among BVDV subtypes affect diagnostic and vaccine performance.
Development and Critical Evaluation of Diagnostic
Tests
Validation of diagnostic tests available in the U.S.
Innovative test development
Critical Evaluation of Current Vaccines
Fetal protection challenge studies for all USDA licensed vaccines
Effective models for acute challenge for the postnatal susceptible calf
Duration of immunity after BVDV vaccination
Investigate the Pathogenesis of BVDV in Cattle Based on Disease
Predisposition and Genetics
Genetics for infectious disease resistance/susceptibility relating to BVDV
Critical Issues Facing BVDV Programs and Various Groups Definition and agreement on goals of
control and eradicationAdequate funding at federal- state levels
Private and corporate , producer organizations
Collaborative research teams Unified voice on control programs to the
producersNumerous groups already involved
Potential of a national committee with range of participants