January 2013 Refill

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E-NEWSLETTER OF THE UNIVERSITY OF TOLEDO COLLEGE OF PHARMACY AND PHARMACEUTICAL SCIENCES Distinguished University Professor Dr. Paul Erhardt, professor of Medicinal and Biological Chemistry and Director of the Center for Drug Design and Development (CD3) has been a faculty member at The University of Toledo for 18 years. He earned his B.A. in Chemistry and his Ph.D. in Medicinal Chemistry from University of Minnesota before accepting a postdoctoral position in bio-analytical chemistry at the University of Texas-Austin. He then spent almost 20 years in industry, rising to Assistant Director of Research and Development at Berlex Laboratories before joining the College of Pharmacy and Pharmaceutical Sciences (CPPS) in 1994. Dr. Erhardt is a medicinal chemist with an international reputation for his research in the area of drug design and development. In 2002, he was elected President of the International Union of Pure and Applied Chemistry (IUPAC) Division VII Chemistry and Human Health. In 2007, he was awarded the IUPAC Appreciation of Service Award for Outstanding Contributions to the Advancement of Worldwide Chemistry. He has displayed international leadership in Medicinal Chemistry, including presenting exciting new ideas and predicting future directions in the field. Dr. Erhardt was awarded a special gold medal to recognize his innovation in medicinal chemistry by the Indian Society of Chemists and Biologists at the 2011 International Conference on Chemistry for Mankind. Dr. Erhardt‟s research career embodies highly creative and original work with many notable contributions. For example, his discovery and chemical development of esmolol (Brevibloc®) served to lay a solid foundation for his reputation among his peers. Esmolol, an ultra-short-acting beta blocker, is used primarily in surgeries, and the story of esmolol's discovery has been documented in the prestigious American Chemical Society series entitled Chronicles of Drug Discovery. He currently has a number of additional drug candidates in various stages of the drug development process in the Center for Drug Design and Development (CD3). Dr. Erhardt has been exceptionally successful in garnering extramural research funding from a variety of agencies, totaling about $7M; this includes strong support ($3.4M) from the United States Department of Agriculture (USDA), $600,000 from Pfizer and $636,000 from the U.S. Army. Dr. Erhardt has a notable body of research work: 77 papers published or in press, 32 issued patents and applications (14 from work at UT), and 32 published reviews and book chapters. In recognition of his outstanding and sustained research JANUARY 2013 01 x ReFILL Medicinal Chemistry BS/MS 2012 welcomed the college‟s first students into the BS/MS in Medicinal Chemistry program. Students in this new program have the opportunity to complete both a BS and an MS degree in five calendar years. Students in the B.S. in Pharmaceutical Sciences program have the option of completing some of the graduate course work during their junior and senior years as part of this accelerated program. These students, who complete a required research internship during the summer after the junior year, continue their research with the same mentor during the graduate portion of the program. This offers undergraduate students who intend to pursue graduate studies an additional option for continuing their research with the faculty of the College of Pharmacy and Pharmaceutical Sciences. Continued on page 2 Dr. Erhardt (center) with (L-R) Brian Kress, Neha Malik, Rachael Jetson, and Dr. Chris Trabbic. this issue Dr. Paul Erhardt, DUP P.1 Building Bridges P.2 UT Migrant Programs P.3 Young Pharmacy Leaders P.4 A University Rising P.4

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The e-newsletter of The University of Toledo College of Pharmacy and Pharmaceutical Sciences

Transcript of January 2013 Refill

E-NEWSLETTER OF THE

UNIVERSITY OF TOLEDO

COLLEGE OF PHARMACY AND

PHARMACEUTICAL SCIENCES

Distinguished University Professor

Dr. Paul Erhardt, professor of Medicinal and Biological Chemistry and Director of the Center for Drug Design and Development (CD3) has been a faculty member at The University of Toledo for 18 years. He earned his B.A. in Chemistry and his Ph.D. in Medicinal Chemistry from University of Minnesota before accepting a postdoctoral position in bio-analytical chemistry at the University of Texas-Austin. He then spent almost 20 years in industry, rising to Assistant Director of Research and Development at Berlex Laboratories before joining the College of Pharmacy and Pharmaceutical Sciences (CPPS) in 1994.

Dr. Erhardt is a medicinal chemist with an international reputation for his research in the area of drug design and development. In 2002, he was elected President of the International Union of Pure and Applied Chemistry (IUPAC) Division VII Chemistry and Human Health. In 2007, he was awarded the IUPAC Appreciation of Service Award for Outstanding Contributions to the Advancement of Worldwide Chemistry. He has displayed international leadership in Medicinal Chemistry, including presenting exciting new ideas and predicting future directions in the field. Dr. Erhardt was awarded a special gold medal to recognize his innovation in medicinal chemistry by the Indian

Society of Chemists and Biologists at the 2011 International Conference on Chemistry for Mankind.

Dr. Erhardt‟s research career embodies highly creative and original work with many notable contributions. For example, his discovery and chemical development of esmolol (Brevibloc®) served to lay a solid foundation for his reputation among his peers. Esmolol, an ultra-short-acting beta blocker, is used primarily in surgeries, and the story of esmolol's discovery has been documented in the prestigious American Chemical Society series entitled Chronicles of Drug Discovery. He currently has a number of additional drug candidates in various stages of the drug development process in the Center for Drug Design and Development (CD3).

Dr. Erhardt has been exceptionally successful in garnering extramural research funding from a variety of agencies, totaling about $7M; this includes strong support ($3.4M) from the United States Department of Agriculture (USDA), $600,000 from Pfizer and $636,000 from the U.S. Army. Dr. Erhardt has a notable body of research work: 77 papers published or in press, 32 issued patents and applications (14 from work at UT), and 32 published reviews and book chapters. In recognition of his outstanding and sustained research

J A N U A R Y

2 0 1 3

01 x ReFILL

Medicinal Chemistry BS/MS

2012 welcomed the

college‟s first students

into the BS/MS in

Medicinal Chemistry

program. Students in this

new program have the

opportunity to complete

both a BS and an MS

degree in five calendar

years.

Students in the B.S. in

Pharmaceutical

Sciences program have

the option of completing

some of the graduate

course work during their

junior and senior years

as part of this

accelerated program.

These students, who

complete a required

research internship

during the summer after

the junior year, continue

their research with the

same mentor during the

graduate portion of the

program. This offers

undergraduate students

who intend to pursue

graduate studies an

additional option for

continuing their research

with the faculty of the

College of Pharmacy

and Pharmaceutical

Sciences. Cont i nue d o n p age 2

Dr. Erhardt (center) with (L-R) Brian Kress, Neha Malik,

Rachael Jetson, and Dr. Chris Trabbic.

this issue

Dr. Paul Erhardt, DUP P.1

Building Bridges P.2

UT Migrant Programs P.3

Young Pharmacy Leaders P.4

A University Rising P.4

Building Bridges

Among the many positive

outcomes of the college‟s

various international

partnerships are the cross-

cultural interactions and

collaborations among

faculty and student at

partner institutions.

The college‟s relationship

with Al-Zaytoonah

University in Amman,

Jordan represents such an

exchange of ideas and

knowledge that enriches the

experiences of students

and faculty alike.

Recently, the College of

Pharmacy and

Pharmaceutical Sciences

jointly sponsored a

conference with the faculty

of pharmacy from Al-

Zaytoonah University. The

conference, which was held

in Amman, featured

discussions about

pharmaceutical care and

treatment of various

diseases.

Al-Zaytoonah, a private

university with over 8000

students, has a thriving

pharmacy program that

offers a well rounded

curriculum in the

pharmaceutical sciences.

The College

collaborates with the

pharmacy faculty of

Al-Zaytoonah

University in Jordan.

In addition to Dr. Early

giving the keynote address

at the conference, Drs.

Amanda Bryant-Friedrich,

Sharrel Pinto and Youssef

Sari presented, and two

graduate students from the

Department of Medicinal

Chemistry attended. Dr. M.

Kahlil Mohammad, an

alumnus of UT‟s Medicinal

Chemistry PhD program,

also presented at the

conference.

Dr. Amanda Bryant-

Friedrich, associate

professor in the Department

of Medicinal Chemistry,

presented her research on

chemical toxicology and the

treatment of cancer.

Dr. Sharrel Pinto, associate

professor in the Department

of Pharmacy Practice,

noted that “the level of the

pharmacy profession in

Jordan now is comparable

to the level of the

profession in the United

States 10 years ago.” She

believes that Jordan can

develop the profession

further by collaborating with

American institutions and

by increasing the

involvement of pharmacists

in clinical practice.

Dr. Youssef Sari, assistant

professor of pharmacology,

was impressed with the

global reach of the research

from internationally refereed

journals. His conference

presentation involved his

research on the treatment

of alcoholism and

neurodegenerative

diseases. During the

conference, Drs. Early and

Sari were featured on the

PharmaJo website and on

Jordanian television.

“I am so pleased that we

are able to continually

showcase, on an

international stage, the

scientific talent of our

faculty—from pharmacy

practice to chemistry to

pharmacology,” stated

Dean Early.

The conference generated

significant interest in the

college‟s graduate

programs. The college

plans to host another

conference with the Al-

Zaytoonah pharmacy

faculty in 2014.

accomplishments, the UT College of Pharmacy and Pharmaceutical Sciences has recognized him several times, including the Outstanding Research Faculty Award in 2004 and the Excellence Award for Research in 2009 and 2010. Further, The University of Toledo recognized him with the Outstanding Research Faculty Award in 2006.

Dr. Paul Erhardt‟s mentorship of all individuals in the CD3 is legendary. Dr. Erhardt is known for the combination of first-class technical training and generosity of spirit that has been extended to more than 50 individuals during his time at UT. He has mentored nineteen undergraduate students, twenty graduate students, fourteen postdoctoral fellows, and six sabbatical visitors, many of whom have stated that he had a profound and life changing impact on their lives. For those contributions, the CPPS recognized him with the Outstanding Faculty Teaching Award in 1995.

Over the years, Dr. Erhardt has delivered seminars and invited lectures across the globe, including India, China and South America, and been generous with his time for service both at UT and internationally.

Distinguished University Professor

( c o n t i n ue d f r o m p a g e 1 )

(L-R) Drs. Sari, Al Mogarry, Early, Bryant-Friedrich and Pinto with

Norah Al-Mogri.

Alumni at Young Pharmacy Leaders Conference

Drs. Kenneth and

Scarlett (Lynn) Hohmeier

(PharmD ‟10 and ‟12,

respectively) were two of

the 10 young

pharmacists selected to

attend Ohio‟s 2012

Young Pharmacy

Leaders Conference at

the Ohio Pharmacists

Association in Columbus.

The purpose of the

Leadership Conference

is to identify emerging

leaders, enhance the

leadership skills of

participants, and provide

motivation to seek

greater awareness and

involvement in issues

confronting healthcare

and the profession of

pharmacy. This

invitational Conference

includes pharmacists

who have been practicing

fewer than 10 years, as

well as student

pharmacist leaders from

the Ohio colleges of

pharmacy. Three UT

PharmD students also

participated in the

conference, along with

pharmacist leaders from

the Ohio Pharmacists

Association. Ken

Hohmeier is the

pharmacy manager at

Buderer Compounding

Pharmacy in Avon, Ohio,

where Scarlett Hohmeier

is a clinical pharmacist.

The University of Toledo

hosts Migrant Programs

each year to give children

of migrant workers, who

often relocate frequently,

the UT experience.

Elementary and a few high

school students get a

glimpse of college life, from

visiting the Glass Bowl to

creating flashlights in the

College of Engineering and

making silly putty in the

College of Pharmacy and

Pharmaceutical Sciences

(pictured above).

José Treviňo, Director of

Transfer Services and

Recruitment for the College

of Pharmacy and

Pharmaceutical Sciences,

is heavily involved in the

planning and execution of

this annual program. The

college has participated for

11 years, first visiting the

migrant camp and later

engaging students during

the annual campus visits.

The program now includes

the College of Engineering,

whose portion of the visit is

led by Dr. Mark Pickett.

“Our goal,” said Treviňo, “is

to have these

students one

day attend UT

as students

pursuing

pharmacy and

engineering

careers. This

program

helps these

students learn

about careers

that would take them from

being farm workers to being

just about anything they

want as long as they are

willing to work for it.”

Students participate in

several hands-on activities

have a pizza and ice-cream

lunch during their day on

campus. They also

complete a campus tour.

The opportunity to visit UT

and envision a future

beyond farming is essential

to the future success of the

participants in the Migrant

Programs. This matter is

personal to Treviňo, who

was a farm worker until the

age of fifteen.

“I know how hard this type of work is,” said Treviňo. “I also know that if you are willing to work hard at academics, there is no telling how far you can go.”

Students always respond

enthusiastically to the

program and write

elaborate „thank you‟ notes

each year expressing their

excitement about UT.

UT’s Migrant Programs introduce young

students to pharmacy

3000 Arlington Ave, MS 1013

Toledo, OH 43614

419.383.1904 ph

419.383.1907 fax

www.utoledo.edu/pharmacy

A University Rising: Research and Scholarship

The University of Toledo has initiated a new fund raising campaign with the

theme A University Rising. The goal of this university-wide capital

campaign is to support UT‟s growth and to lead the way in academics and

research in a manner that will gain UT further national and international

prominence.

The college‟s role in the capital campaign is to raise funds for research and

scholarships that enhance the education of pharmacy and pharmaceutical

science students. Dr. Robert Schlembach, professor emeritus and historian,

is the chair of the college‟s campaign. Doc‟s sense of indebtedness to the

college for the excellent education he received and for the lifelong

relationships he has made compelled him to serve by chairing the current

giving campaign.

“Giving not only provides an investment in the bright future of the College of

Pharmacy and Pharmaceutical Sciences,” said Dr. Schlembach, “it also

continues to pave the way for an excellent professional education of which

every University of Toledo alumnus can be proud.”

The college will also honor Doc and his service to the college throughout the

campaign, and alumni are welcomed to participate.

For more information about contributing to the campaign, please contact the

college‟s development director, Jeff Barton, at 419.530.5413 or

[email protected]. The university‟s annual Phon-a-Thon, during

which current students call alumni to raise funds for the university, will also

offer opportunities to contribute.

Upcoming Events

Ice Skating Party

Sunday, February 10, 2013

4:00 - 5:30 p.m.

Tam O‟ Shanter in Sylvania, Ohio

The Alumni Affiliates of the College of Medicine and Life Sciences and the College of Pharmacy and Pharmaceutical Sciences will co-host this event.

The event is free; however, online registration is required.