JAHA: Journal of the American Heart Associationjaha.ahajournals.org/content/ahaoa/3/3.toc.pdf ·...

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Editorials Reducing Readmissions: What Might it Take? Ashish K. Jha e001080 doi: 10.1161/JAHA.114.001080 Prognostic Power of Mitral Annulus Indices of Left Ventricular Diastolic Function Sherif F. Nagueh e001012 doi: 10.1161/JAHA.114.001012 Need for Elective PCI Prior to Noncardiac Surgery: High Risk Through the Eyes of the Beholder Santiago Garcia and Edward O. Mcfalls e001068 doi: 10.1161/JAHA.114.001068 Dispatcher-Directed CPR: An All-Ages Strategy to Improve Cardiac Arrest Survival Thomas Rea e000942 doi: 10.1161/JAHA.114.000942 Priming Mononuclear Cells to Improve Outcomes of Regenerative Therapy Kashyap Choksi and Buddhadeb Dawn e001168 doi: 10.1161/JAHA.114.001168 Original Research Arrhythmia and Electrophysiology Predisposing Factors Associated With Development of Persistent Compared With Paroxysmal Atrial Fibrillation Roopinder K. Sandhu, David Conen, Usha B. Tedrow, Kathryn C. Fitzgerald, Aruna D. Pradhan, Paul M Ridker, Robert J. Glynn, and Christine M. Albert e000916 doi: 10.1161/JAHA.114.000916 Phosphorylation of Shox2 Is Required for Its Function to Control Sinoatrial Node Formation Hongbing Liu, Chao-Hui Chen, Wenduo Ye, Ramón A. Espinoza-Lewis, Xuefeng Hu, Yanding Zhang, and YiPing Chen e000796 doi: 10.1161/JAHA.114.000796 Interventricular Differences in β-Adrenergic Responses in the Canine Heart: Role of Phosphodiesterases Cristina E. Molina, Daniel M. Johnson, Hind Mehel, Roel L. H. M. G. Spätjens, Delphine Mika, Vincent Algalarrondo, Zeineb Haj Slimane, Patrick Lechêne, Najah Abi-Gerges, Henk J. van der Linde, Jérôme Leroy, Paul G. A. Volders, Rodolphe Fischmeister, Grégoire Vandecasteele e000858 doi: 10.1161/JAHA.114.000858 Symptomatic Presentation of Carotid Sinus Hypersensitivity Is Associated With Impaired Cerebral Autoregulation Maw Pin Tan, Tom J. Chadwick, Simon R. J. Kerr, and Steve W. Parry e000514 doi: 10.1161/JAHA.113.000514 Arrhythmogenic Calmodulin Mutations Disrupt Intracellular Cardiomyocyte Ca 2+ Regulation by Distinct Mechanisms Guo Yin, Faisal Hassan, Ayman R. Haroun, Lisa L. Murphy, Lia Crotti, Peter J. Schwartz, Alfred L. George, Jr, and Jonathan Satin e000996 doi: 10.1161/JAHA.114.000996 JAHA: Journal of the American Heart Association Volume 3, Issue 3 June 2014 by guest on May 16, 2018 http://jaha.ahajournals.org/ Downloaded from

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Page 1: JAHA: Journal of the American Heart Associationjaha.ahajournals.org/content/ahaoa/3/3.toc.pdf · Phillip T. Burch, Eric Gerstenberger, Chitra Ravishankar, David A. Hehir, Ryan R.

Editorials Reducing Readmissions: What Might it Take? Ashish K. Jha e001080 doi: 10.1161/JAHA.114.001080

Prognostic Power of Mitral Annulus Indices of Left Ventricular Diastolic Function Sherif F. Nagueh e001012 doi: 10.1161/JAHA.114.001012

Need for Elective PCI Prior to Noncardiac Surgery: High Risk Through the Eyes of the Beholder Santiago Garcia and Edward O. Mcfalls e001068 doi: 10.1161/JAHA.114.001068

Dispatcher-Directed CPR: An All-Ages Strategy to Improve Cardiac Arrest Survival Thomas Rea e000942 doi: 10.1161/JAHA.114.000942

Priming Mononuclear Cells to Improve Outcomes of Regenerative Therapy Kashyap Choksi and Buddhadeb Dawn e001168 doi: 10.1161/JAHA.114.001168

Original Research Arrhythmia and Electrophysiology

Predisposing Factors Associated With Development of Persistent Compared With Paroxysmal Atrial Fibrillation Roopinder K. Sandhu, David Conen, Usha B. Tedrow, Kathryn C. Fitzgerald, Aruna D. Pradhan, Paul M Ridker, Robert J. Glynn, and Christine M. Albert e000916 doi: 10.1161/JAHA.114.000916

Phosphorylation of Shox2 Is Required for Its Function to Control Sinoatrial Node Formation Hongbing Liu, Chao-Hui Chen, Wenduo Ye, Ramón A. Espinoza-Lewis, Xuefeng Hu, Yanding Zhang, and YiPing Chen e000796 doi: 10.1161/JAHA.114.000796

Interventricular Differences in β-Adrenergic Responses in the Canine Heart: Role of Phosphodiesterases Cristina E. Molina, Daniel M. Johnson, Hind Mehel, Roel L. H. M. G. Spätjens, Delphine Mika, Vincent Algalarrondo, Zeineb Haj Slimane, Patrick Lechêne, Najah Abi-Gerges, Henk J. van der Linde, Jérôme Leroy, Paul G. A. Volders, Rodolphe Fischmeister, Grégoire Vandecasteelee000858 doi: 10.1161/JAHA.114.000858

Symptomatic Presentation of Carotid Sinus Hypersensitivity Is Associated With Impaired Cerebral Autoregulation Maw Pin Tan, Tom J. Chadwick, Simon R. J. Kerr, and Steve W. Parry e000514 doi: 10.1161/JAHA.113.000514

Arrhythmogenic Calmodulin Mutations Disrupt Intracellular Cardiomyocyte Ca 2+ Regulation by Distinct Mechanisms Guo Yin, Faisal Hassan, Ayman R. Haroun, Lisa L. Murphy, Lia Crotti, Peter J. Schwartz, Alfred L. George, Jr, and Jonathan Satin e000996 doi: 10.1161/JAHA.114.000996

JAHA: Journal of the American Heart AssociationVolume 3, Issue 3

June 2014

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Page 2: JAHA: Journal of the American Heart Associationjaha.ahajournals.org/content/ahaoa/3/3.toc.pdf · Phillip T. Burch, Eric Gerstenberger, Chitra Ravishankar, David A. Hehir, Ryan R.

Atrial Fibrillation in Hypertrophic Cardiomyopathy: Prevalence, Clinical Correlations, and Mortality in a Large High-Risk Population Konstantinos C. Siontis, Jeffrey B. Geske, Kevin Ong, Rick A. Nishimura, Steve R. Ommen, and Bernard J. Gersh e001002 doi: 10.1161/JAHA.114.001002

Congenital Heart Disease Vulnerability of the Developing Heart to Oxygen Deprivation as a Cause of Congenital Heart Defects Doreswamy Kenchegowda, Hongbin Liu, Keyata Thompson, Liping Luo, Stuart S. Martin, and Steven A. Fisher e000841 doi: 10.1161/JAHA.114.000841

Longitudinal Assessment of Growth in Hypoplastic Left Heart Syndrome: Results From the Single Ventricle Reconstruction Trial Phillip T. Burch, Eric Gerstenberger, Chitra Ravishankar, David A. Hehir, Ryan R. Davies, Steven D. Colan, Lynn A. Sleeper, Jane W. Newburger, Martha L. Clabby, Ismee A. Williams, Jennifer S. Li, Karen Uzark, David S. Cooper, Linda M. Lambert, Victoria L. Pemberton, Nancy A. Pike, Jeffrey B. Anderson, Carolyn Dunbar-Masterson, Svetlana Khaikin, Sinai C. Zyblewski, and L. LuAnn Minich For the Pediatric Heart Network Investigatorse000079 doi: 10.1161/JAHA.114.000079

Coronary Heart Disease Effect of Diet or Diet Plus Physical Activity Versus Usual Care on Inflammatory Markers in Patients with Newly Diagnosed Type 2 Diabetes: The Early ACTivity In Diabetes (ACTID) Randomized, Controlled Trial Dylan Thompson, Jean-Philippe Walhin, Alan M. Batterham, Keith A. Stokes, Ashley R. Cooper, and Robert C. Andrews e000828 doi: 10.1161/JAHA.114.000828

Clinical Features and Prognosis of Patients With Coronary Spasm–Induced Non–ST-Segment Elevation Acute Coronary Syndrome Naoki Nakayama, Koichi Kaikita, Takashi Fukunaga, Yasushi Matsuzawa, Koji Sato, Eiji Horio, Hiromi Yoshimura, Michio Mizobe, Seiji Takashio, Kenichi Tsujita, Sunao Kojima, Shinji Tayama, Seiji Hokimoto, Tomohiro Sakamoto, Koichi Nakao, Seigo Sugiyama, Kazuo Kimura, and Hisao Ogawa e000795 doi: 10.1161/JAHA.114.000795

Functional Analysis of the TRIB 1 Associated Locus Linked to Plasma Triglycerides and Coronary Artery Disease Adrianna Douvris, Sébastien Soubeyrand, Thet Naing, Amy Martinuk, Majid Nikpay, Andrew Williams, Julie Buick, Carole Yauk, and Ruth McPherson e000884 doi: 10.1161/JAHA.114.000884

Decreased Myocardial Dendritic Cells is Associated With Impaired Reparative Fibrosis and Development of Cardiac Rupture After Myocardial Infarction in Humans Toshiyuki Nagai, Satoshi Honda, Yasuo Sugano, Taka-aki Matsuyama, Keiko Ohta-Ogo, Yasuhide Asaumi, Yoshihiko Ikeda, Kengo Kusano, Masaharu Ishihara, Satoshi Yasuda, Hisao Ogawa, Hatsue Ishibashi-Ueda, and Toshihisa Anzai e000839 doi: 10.1161/JAHA.114.000839

ECG Morphological Variability in Beat Space for Risk Stratification After Acute Coronary Syndrome Yun Liu, Zeeshan Syed, Benjamin M. Scirica, David A. Morrow, John V. Guttag, and Collin M. Stultz e000981 doi: 10.1161/JAHA.114.000981

Epidemiology Long-term Cardiovascular Risks Associated With an Elevated Heart Rate: The Framingham Heart Study Jennifer E. Ho, Martin G. Larson, Anahita Ghorbani, Susan Cheng, Erin E. Coglianese, Ramachandran S. Vasan, and Thomas J. Wang e000668 doi: 10.1161/JAHA.113.000668

Population-Based Incidence of Sudden Cardiac and Unexpected Death Before and After the 2011 Earthquake and Tsunami in Iwate, Northeast Japan Masanobu Niiyama, Fumitaka Tanaka, Satoshi Nakajima, Tomonori Itoh, Tatsuya Matsumoto, Mikio Kawakami, Yujiro Naganuma, Shinichi Omama, Takashi Komatsu, Toshiyuki Onoda, Kiyomi Sakata, Takashi Ichikawa, and Motoyuki Nakamura e000798 doi: 10.1161/JAHA.114.000798

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Page 3: JAHA: Journal of the American Heart Associationjaha.ahajournals.org/content/ahaoa/3/3.toc.pdf · Phillip T. Burch, Eric Gerstenberger, Chitra Ravishankar, David A. Hehir, Ryan R.

Electrocardiographic Precordial ST-Segment Deviations and the Risk of Cardiovascular Death: Results From the Copenhagen ECG Study Peter Vibe Rasmussen, Jonas Bille Nielsen, Adrian Pietersen, Claus Graff, Bent Lind, Johannes Jan Struijk, Morten Salling Olesen, Stig Haunsø, Lars Køber, Jesper Hastrup Svendsen, and Anders Gaarsdal Holst e000549 doi: 10.1161/JAHA.113.000549

Severity of Cardiovascular Disease Outcomes Among Patients With HIV Is Related to Markers of Inflammation and Coagulation Anna D. Nordell, Matthew McKenna, Álvaro H. Borges, Daniel Duprez, Jacqueline Neuhaus, and James D. Neaton for the INSIGHT SMART, ESPRIT Study Groups, and SILCAAT Scientific Committee e000844 doi: 10.1161/JAHA.114.000844

Dabigatran Etexilate and Risk of Myocardial Infarction, Other Cardiovascular Events, Major Bleeding, and All-Cause Mortality: A Systematic Review and Meta-analysis of Randomized Controlled Trials Jonathan Douxfils, Fanny Buckinx, François Mullier, Valentine Minet, Véronique Rabenda, Jean-Yves Reginster, Philippe Hainaut, Olivier Bruyère, and Jean-Michel Dogné e000515 doi: 10.1161/JAHA.113.000515

Fibroblast Growth Factor-23 and Incident Coronary Heart Disease, Heart Failure, and Cardiovascular Mortality: The Atherosclerosis Risk In Communities Study Pamela L. Lutsey, Alvaro Alonso, Elizabeth Selvin, James S. Pankow, Erin D. Michos, Sunil K. Agarwal, Laura R. Loehr, John H. Eckfeldt, and Josef Coresh e000936 doi: 10.1161/JAHA.114.000936

The American Heart Association Life’s Simple 7 and Incident Cognitive Impairment: The REasons for Geographic And Racial Differences in Stroke (REGARDS) Study Evan L. Thacker, Sarah R. Gillett, Virginia G. Wadley, Frederick W. Unverzagt, Suzanne E. Judd, Leslie A. McClure, Virginia J. Howard, and Mary Cushman e000635 doi: 10.1161/JAHA.113.000635

Sex and Age Differences in the Association of Depression With Obstructive Coronary Artery Disease and Adverse Cardiovascular Events Amit J. Shah, Nima Ghasemzadeh, Elisa Zaragoza-Macias, Riyaz Patel, Danny J. Eapen, Ian J. Neeland, Pratik M. Pimple, A. Maziar Zafari, Arshed A. Quyyumi, and Viola Vaccarino e000741 doi: 10.1161/JAHA.113.000741

Plasma Levels of the Proinflammatory Chitin-Binding Glycoprotein YKL-40, Variation in the Chitinase 3-Like 1 Gene ( CHI3L1 ), and Incident Cardiovascular Events Paul M Ridker, Daniel I. Chasman, Lynda Rose, Joseph Loscalzo, and Jack A. Elias e000897 doi: 10.1161/JAHA.114.000897

Television Viewing, Computer Use, Time Driving and All-Cause Mortality: The SUN Cohort Francisco Javier Basterra-Gortari, Maira Bes-Rastrollo, Alfredo Gea, Jorge María Nú ñez-Córdoba, Estefanía Toledo, and Miguel Ángel Martínez-González e000864 doi: 10.1161/JAHA.114.000864

Plasma Phospholipid Saturated Fatty Acids and Incident Atrial Fibrillation: The Cardiovascular Health Study Amanda M. Fretts, Dariush Mozaffarian, David S. Siscovick, Luc Djousse, Susan R. Heckbert, Irena B. King, Barbara McKnight, Colleen Sitlani, Frank M. Sacks, Xiaoling Song, Nona Sotoodehnia, Donna Spiegelman, Erin R. Wallace, and Rozenn N. Lemaitre e000889 doi: 10.1161/JAHA.114.000889

Associations of Stressful Life Events and Social Strain With Incident Cardiovascular Disease in the Women’s Health Initiative Kiarri N. Kershaw, Gretchen A. Brenes, Luenda E. Charles, Mace Coday, Martha L. Daviglus, Natalie L. Denburg, Candyce H. Kroenke, Monika M. Safford, Tina Savla, Hilary A. Tindle, Lesley F. Tinker, and Linda Van Horn e000687 doi: 10.1161/JAHA.113.000687

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Page 4: JAHA: Journal of the American Heart Associationjaha.ahajournals.org/content/ahaoa/3/3.toc.pdf · Phillip T. Burch, Eric Gerstenberger, Chitra Ravishankar, David A. Hehir, Ryan R.

Plasma Levels of Fetuin-A and Risk of Coronary Heart Disease in US Women: The Nurses’ Health Study Qi Sun, Monik C. Jiménez, Mary K. Townsend, Eric B. Rimm, JoAnn E. Manson, Christine M. Albert, and Kathryn M. Rexrode e000939 doi: 10.1161/JAHA.114.000939

Genetics Haptoglobin 2-2 Genotype is Not Associated With Cardiovascular Risk in Subjects With Elevated Glycohemoglobin—Results From the Bruneck Study Raimund Pechlaner, Stefan Kiechl, Peter Willeit, Egon Demetz, Margot Haun, Siegfried Weger, Friedrich Oberhollenzer, Florian Kronenberg, Enzo Bonora, Günter Weiss, and Johann Willeit e000732 doi: 10.1161/JAHA.113.000732

Health Services and Outcomes Research Health System Characteristics and Rates of Readmission After Acute Myocardial Infarction in the United States Jeremiah R. Brown, Chiang-Hua Chang, Weiping Zhou, Todd A. MacKenzie, David J. Malenka, and David C. Goodman e000714 doi: 10.1161/JAHA.113.000714

Psychometric Evaluation of the Care Transition Measure in TRACE-CORE: Do We Need a Better Measure? Milena D. Anatchkova, Constance M. Barysauskas, Rebecca L. Kinney, Catarina I. Kiefe, Arlene S. Ash, Lisa Lombardini, and Jeroan J. Allison e001053 doi: 10.1161/JAHA.114.001053

Patterns of Care Quality and Prognosis Among Hospitalized Ischemic Stroke Patients With Chronic Kidney Disease Bruce Ovbiagele, Lee H. Schwamm, Eric E. Smith, Maria V. Grau-Sepulveda, Jeffrey L. Saver, Deepak L. Bhatt, Adrian F. Hernandez, Eric D. Peterson, and Gregg C. Fonarow e000905 doi: 10.1161/JAHA.114.000905

Hospital Variation in Survival Trends for In-hospital Cardiac Arrest Saket Girotra, Peter Cram, John A. Spertus, Brahmajee K. Nallamothu, Yan Li, Philip G. Jones, and Paul S. Chan The American Heart Association’s Get With the GuidelinesR-Resuscitation Investigators e000871 doi: 10.1161/JAHA.114.000871

Heart Failure Association of Comorbidity Burden With Abnormal Cardiac Mechanics: Findings From the HyperGEN Study Senthil Selvaraj, Frank G. Aguilar, Eva E. Martinez, Lauren Beussink, Kwang-Youn A. Kim, Jie Peng, Laura Rasmussen-Torvik, Jin Sha, Marguerite R. Irvin, C. Charles Gu, Cora E. Lewis, Steven C. Hunt, Donna K. Arnett, and Sanjiv J. Shah e000631 doi: 10.1161/JAHA.113.000631

Prognostic Value of Left Ventricular Diastolic Dysfunction in a General Population Tatiana Kuznetsova, Lutgarde Thijs, Judita Knez, Lieven Herbots, Zhenyu Zhang, and Jan A. Staessen e000789 doi: 10.1161/JAHA.114.000789

Carotid Intima-Media Thickness is Associated With Incident Heart Failure Among Middle-Aged Whites and Blacks: The Atherosclerosis Risk in Communities Study Valery S. Effoe, Carlos J. Rodriguez, Lynne E. Wagenknecht, Gregory W. Evans, Patricia P. Chang, Maria C. Mirabelli, and Alain G. Bertoni e000797 doi: 10.1161/JAHA.114.000797

Self-Rated Health Predicts Healthcare Utilization in Heart Failure Alanna M. Chamberlain, Sheila M. Manemann, Shannon M. Dunlay, John A. Spertus, Debra K. Moser, Cecilia Berardi, Robert L. Kane, Susan A. Weston, Margaret M. Redfield, and Véronique L. Roger e000931 doi: 10.1161/JAHA.114.000931

Postextrasystolic Blood Pressure Potentiation Predicts Poor Outcome of Cardiac Patients Daniel Sinnecker, Ralf J. Dirschinger, Petra Barthel, Alexander Müller, Adrian Morley-Davies, Alexander Hapfelmeier, Michael Dommasch, Katharina M. Huster, Gerd Hasenfuss, Karl-Ludwig Laugwitz, Marek Malik, and Georg Schmidt e000857 doi: 10.1161/JAHA.114.000857

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Protein Changes Contributing to Right Ventricular Cardiomyocyte Diastolic Dysfunction in Pulmonary Arterial Hypertension Silvia Rain, Denielli da Silva Goncalves Bos, M. Louis Handoko, Nico Westerhof, Ger Stienen, Coen Ottenheijm, Max Goebel, Peter Dorfmüller, Christophe Guignabert, Marc Humbert, Harm-Jan Bogaard, Cris dos Remedios, Chandra Saripalli, Carlos G. Hidalgo, Henk L. Granzier, Anton Vonk-Noordegraaf, Jolanda van der Velden, and Frances S. de Man e000716 doi: 10.1161/JAHA.113.000716

Temporal Trends in Incidence and Outcomes of Peripartum Cardiomyopathy in the United States: A Nationwide Population-Based Study Dhaval Kolte, Sahil Khera, Wilbert S. Aronow, Chandrasekar Palaniswamy, Marjan Mujib, Chul Ahn, Diwakar Jain, Alan Gass, Ali Ahmed, Julio A. Panza, and Gregg C. Fonarow e001056 doi: 10.1161/JAHA.114.001056

Assessment of a University of California, Los Angeles 4-Variable Risk Score for Advanced Heart Failure Ulrik Sartipy, Ayumi Goda, Donna M. Mancini, and Lars H. Lund e000998 doi: 10.1161/JAHA.114.000998

Cardiac CD47 Drives Left Ventricular Heart Failure Through Ca 2+ -CaMKII-Regulated Induction of HDAC3 Maryam Sharifi-Sanjani, Ali Hakim Shoushtari, Marisol Quiroz, Jeffrey Baust, Samuel F. Sestito, Mackenzie Mosher, Mark Ross, Charles F. McTiernan, Claudette M. St. Croix, Richard A. Bilonick, Hunter C. Champion, and Jeffrey S. Isenberg e000670 doi: 10.1161/JAHA.113.000670

B-Type Natriuretic Peptide Predicts 30-Day Readmission for Heart Failure but not Readmission for Other Causes Kelsey M. Flint, Larry A. Allen, Michael Pham, and Paul A. Heidenreich e000806 doi: 10.1161/JAHA.114.000806

Decreased Myocardial Injury and Improved Contractility After Administration of a Peptide Derived Against the Alpha-Interacting Domain of the L-Type Calcium Channel Helena M. Viola, Maria C. Jordan, Kenneth P. Roos, and Livia C. Hool e000961 doi: 10.1161/JAHA.114.000961

Functional and Histological Assessment of an Experimental Model of Takotsubo’s Cardiomyopathy Jaspreet Sachdeva, Wangde Dai, and Robert A. Kloner e000921 doi: 10.1161/JAHA.114.000921

Hypertension Smooth Muscle Specific Rac1 Deficiency Induces Hypertension by Preventing p116 RIP 3 -Dependent RhoA Inhibition Gwennan André, Juan E. Sandoval, Kevin Retailleau, Laurent Loufrani, Gilles Toumaniantz, Stefan Offermanns, Malvyne Rolli-Derkinderen, Gervaise Loirand, and Vincent Sauzeau e000852 doi: 10.1161/JAHA.114.000852

Imaging Cardiac Magnetic Resonance Assessment of Interstitial Myocardial Fibrosis and Cardiomyocyte Hypertrophy in Hypertensive Mice Treated With Spironolactone Otavio R. Coelho-Filho, Ravi V. Shah, Tomas G. Neilan, Richard Mitchell, Heitor Moreno, Jr, Raymond Kwong, and Michael Jerosch-Herold e000790 doi: 10.1161/JAHA.114.000790

Interventional Cardiology The Epidemiology and Outcomes of Percutaneous Coronary Intervention Before High-Risk Noncardiac Surgery in Contemporary Practice: Insights From the Blue Cross Blue Shield of Michigan Cardiovascular Consortium (BMC2) Registry Palaniappan Muthappan, Dean Smith, Herbert D. Aronow, Kim Eagle, David Wohns, James Fox, David Share, and Hitinder S. Gurm e000388 doi: 10.1161/JAHA.113.000388

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Delay in Filling First Clopidogrel Prescription After Coronary Stenting Is Associated With an Increased Risk of Death and Myocardial Infarction Nicholas L. Cruden, Jehangir N. Din, Christian Janssen, Reginald Smith, J. David Hilton, W. Peter Klinke, Ron G. Carere, Simon D. Robinson, and Anthony Della Siega e000669 doi: 10.1161/JAHA.113.000669

Defining Unavoidable Delays in Primary Percutaneous Coronary Intervention: Discordance Among Patients Excluded From National Cardiovascular Quality Registries James M. McCabe, Kevin F. Kennedy, and Robert W. Yeh e000944 doi: 10.1161/JAHA.114.000944

Kidney in Cardiovascular Disease The Incidence of Kidney Injury for Patients Treated With a High-Potency Versus Moderate-Potency Statin Regimen After an Acute Coronary Syndrome Amy Sarma, Christopher P. Cannon, James de Lemos, Jean L. Rouleau, Eldrin F. Lewis, Jianping Guo, Jessica L. Mega, Marc S. Sabatine, and Michelle L. O’Donoghue e000784 doi: 10.1161/JAHA.114.000784

Endoplasmic Reticulum Stress Effector CCAAT/Enhancer-binding Protein Homologous Protein (CHOP) Regulates Chronic Kidney Disease–Induced Vascular Calcification Shinobu Miyazaki-Anzai, Masashi Masuda, Kimberly M. Demos-Davies, Audrey L. Keenan, Sommer J. Saunders, Rumiko Masuda, Kristen Jablonski, Maria A. Cavasin, Jessica Kendrick, Michel Chonchol, Timothy A. McKinsey, Moshe Levi, and Makoto Miyazaki e000949 doi: 10.1161/JAHA.114.000949

Molecular Cardiology DNA Methylation is Developmentally Regulated for Genes Essential for Cardiogenesis Alyssa A. Chamberlain, Mingyan Lin, Rolanda L. Lister, Alex A. Maslov, Yidong Wang, Masako Suzuki, Bingruo Wu, John M. Greally, Deyou Zheng, and Bin Zhou e000976 doi: 10.1161/JAHA.114.000976

Calpain-Dependent Cleavage of Junctophilin-2 and T-Tubule Remodeling in a Mouse Model of Reversible Heart Failure Chia-Yen C. Wu, Biyi Chen, Ya-Ping Jiang, Zhiheng Jia, Dwight W. Martin, Shengnan Liu, Emilia Entcheva, Long-Sheng Song, and Richard Z. Lin e000527 doi: 10.1161/JAHA.113.000527

Pediatric Cardiology Temporal Trends in Pulse Pressure and Mean Arterial Pressure During the Rise of Pediatric Obesity in US Children Justin P. Zachariah, Dionne A. Graham, Sarah D. de Ferranti, Ramachandran S. Vasan, Jane W. Newburger, and Gary F. Mitchell e000725 doi: 10.1161/JAHA.113.000725

Resuscitation Science Determinants of Heat Generation in Patients Treated With Therapeutic Hypothermia Following Cardiac Arrest Matthew R. Murnin, Petra Sonder, Gladys N. Janssens, Connie L. Henry, Kees H. Polderman, Jon C. Rittenberger, and Cameron Dezfulian And the Post Cardiac Arrest Service e000580 doi: 10.1161/JAHA.113.000580

Impact of Dispatcher-Assisted Bystander Cardiopulmonary Resuscitation on Neurological Outcomes in Children With Out-of-Hospital Cardiac Arrests: A Prospective, Nationwide, Population-Based Cohort Study Yoshikazu Goto, Tetsuo Maeda, and Yumiko Goto e000499 doi: 10.1161/JAHA.113.000499

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Stroke Risk Factors Associated With Cerebrovascular Recurrence in Symptomatic Carotid Disease: A Comparative Study of Carotid Plaque Morphology, Microemboli Assessment and the European Carotid Surgery Trial Risk Model Nishath Altaf, Neghal Kandiyil, Akram Hosseini, Rajnikant Mehta, Shane MacSweeney, and Dorothee Auer e000173 doi: 10.1161/JAHA.113.000173

Atrial Fibrillation, Stroke, and Anticoagulation in Medicare Beneficiaries: Trends by Age, Sex, and Race, 1992–2010 Gautam R. Shroff, Craig A. Solid, and Charles A. Herzog e000756 doi: 10.1161/JAHA.113.000756

Cost-Effectiveness of Clopidogrel-Aspirin Versus Aspirin Alone for Acute Transient Ischemic Attack and Minor Stroke Yuesong Pan, Anxin Wang, Gaifen Liu, Xingquan Zhao, Xia Meng, Kun Zhao, Liping Liu, Chunxue Wang, S. Claiborne Johnston, Yilong Wang, and Yongjun Wang on behalf of the CHANCE Investigators e000912 doi: 10.1161/JAHA.114.000912

Clinical Prediction Model Suitable for Assessing Hospital Quality for Patients Undergoing Carotid Endarterectomy Neil J. Wimmer, John A. Spertus, Kevin F. Kennedy, H. Vernon Anderson, Jeptha P. Curtis, William S. Weintraub, Mandeep Singh, John S. Rumsfeld, Frederick A. Masoudi, and Robert W. Yeh e000728 doi: 10.1161/JAHA.113.000728

The TeleStroke Mimic (TM)-Score: A Prediction Rule for Identifying Stroke Mimics Evaluated in a Telestroke Network Syed F. Ali, Anand Viswanathan, Aneesh B. Singhal, Natalia S. Rost, Pamela G. Forducey, Lawrence W. Davis, Joseph Schindler, William Likosky, Sherene Schlegel, Nina Solenski, and Lee H. Schwamm on Behalf of Partners Telestroke Network e000838 doi: 10.1161/JAHA.114.000838

HDL-3 is a Superior Predictor of Carotid Artery Disease in a Case-Control Cohort of 1725 Participants Daniel Seung Kim, Amber A. Burt, Elisabeth A. Rosenthal, Jane E. Ranchalis, Jason F. Eintracht, Thomas S. Hatsukami, Clement E. Furlong, Santica Marcovina, John J. Albers, and Gail P. Jarvik e000902 doi: 10.1161/JAHA.114.000902

Valvular Heart Disease Racial Differences in the Prevalence of Severe Aortic Stenosis Devin K. Patel, Kelly D. Green, Marat Fudim, Frank E. Harrell, Jr, Thomas J. Wang, and Mark A. Robbins e000879 doi: 10.1161/JAHA.114.000879

Heart Valve Prostheses in Pregnancy: Outcomes for Women and Their Infants Claire M. Lawley, Charles S. Algert, Jane B. Ford, Tanya A. Nippita, Gemma A. Figtree, and Christine L. Roberts e000953 doi: 10.1161/JAHA.114.000953

Vascular Medicine Identification of Hic–5 as a Novel Scaffold for the MKK4/p54 JNK Pathway in the Development of Abdominal Aortic Aneurysms Xiao-Feng Lei, Joo-ri Kim-Kaneyama, Shigeko Arita-Okubo, Stefan Offermanns, Hiroyuki Itabe, Takuro Miyazaki, and Akira Miyazaki e000747 doi: 10.1161/JAHA.113.000747

Cyclooxygenases 1 and 2 Differentially Regulate Blood Pressure and Cerebrovascular Responses to Acute and Chronic Intermittent Hypoxia: Implications for Sleep Apnea Andrew E. Beaudin, Matiram Pun, Christina Yang, David D. M. Nicholl, Craig D. Steinback, Donna M. Slater, Katherine E. Wynne-Edwards, Patrick J. Hanly, Sofia B. Ahmed, and Marc J. Poulin e000875 doi: 10.1161/JAHA.114.000875

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Arterial Baroreflex Dysfunction Impairs Ischemia-Induced Angiogenesis Changning Hao, Zhen-Hao Huang, Shu-Wei Song, Yi-Qin Shi, Xian Wu Cheng, Toyoaki Murohara, Wei Lu, Ding-Feng Su, and Jun-Li Duan e000804 doi: 10.1161/JAHA.114.000804

Circadian Variation in Vascular Function and Regenerative Capacity in Healthy Humans Ibhar Al Mheid, Frank Corrigan, Farheen Shirazi, Emir Veledar, Qunna Li, Wayne R. Alexander, W. Robert Taylor, Edmund K. Waller, and Arshed A. Quyyumi e000845 doi: 10.1161/JAHA.114.000845

Argonaute-2 Promotes miR-18a Entry in Human Brain Endothelial Cells Raquel Ferreira, Tiago Santos, Arun Amar, Alex Gong, Thomas C. Chen, Stanley M. Tahara, Steven L. Giannotta, and Florence M. Hofman e000968 doi: 10.1161/JAHA.114.000968

Home-Based Walking Exercise in Peripheral Artery Disease: 12-Month Follow-up of the Goals Randomized Trial Mary M. McDermott, Jack M. Guralnik, Michael H. Criqui, Luigi Ferrucci, Lihui Zhao, Kiang Liu, Kathryn Domanchuk, Bonnie Spring, Lu Tian, Melina Kibbe, Yihua Liao, Donald Lloyd Jones, and W. Jack Rejeski e000711 doi: 10.1161/JAHA.113.000711

A Critical Role for the Vascular Endothelium in Functional Neurovascular Coupling in the Brain Brenda R. Chen, Mariel G. Kozberg, Matthew B. Bouchard, Mohammed A. Shaik, and Elizabeth M. C. Hillman e000787 doi: 10.1161/JAHA.114.000787

Vasculogenic Conditioning of Peripheral Blood Mononuclear Cells Promotes Endothelial Progenitor Cell Expansion and Phenotype Transition of Anti-Inflammatory Macrophage and T Lymphocyte to Cells With Regenerative Potential Haruchika Masuda, Rica Tanaka, Satoshi Fujimura, Masakazu Ishikawa, Hiroshi Akimaru, Tomoko Shizuno, Atsuko Sato, Yoshinori Okada, Yumi Iida, Jobu Itoh, Yoshiko Itoh, Hiroshi Kamiguchi, Atsuhiko Kawamoto, and Takayuki Asahara e000743 doi: 10.1161/JAHA.113.000743

Increasing Muscle Mass Improves Vascular Function in Obese ( db/db ) Mice Shuiqing Qiu, James D. Mintz, Christina D. Salet, Weihong Han, Athanassios Giannis, Feng Chen, Yanfang Yu, Yunchao Su, David J. Fulton, and David W. Stepp e000854 doi: 10.1161/JAHA.114.000854

Different Degrees of NADPH Oxidase 2 Regulation and In Vivo Platelet Activation: Lesson From Chronic Granulomatous Disease Roberto Carnevale, Lorenzo Loffredo, Valerio Sanguigni, Alessandro Plebani, Paolo Rossi, Claudio Pignata, Baldassarre Martire, Andrea Finocchi, Maria Cristina Pietrogrande, Chiara Azzari, Anna Rosa Soresina, Silvana Martino, Emilia Cirillo, Francesco Martino, Pasquale Pignatelli, and Francesco Violi e000920 doi: 10.1161/JAHA.114.000920

Contemporary Reviews Pregnancy Complicated by Valvular Heart Disease: An Update Michael Nanna and Kathleen Stergiopoulos e000712 doi: 10.1161/JAHA.113.000712

CorrectionGenetic and Environmental Factors Contributing to Cardiovascular Malformation: A Unified Approach to Riske001071 DOI: 10.1161/JAHA.114.001071

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