Isotope R&D Facility A proposed addition to the HRIBF driver upgrade Mike Saltmarsh HRIBF Users’...
-
Upload
laurel-hall -
Category
Documents
-
view
215 -
download
0
Transcript of Isotope R&D Facility A proposed addition to the HRIBF driver upgrade Mike Saltmarsh HRIBF Users’...
![Page 1: Isotope R&D Facility A proposed addition to the HRIBF driver upgrade Mike Saltmarsh HRIBF Users’ Meeting Nov 13 th 2009.](https://reader033.fdocuments.net/reader033/viewer/2022051820/56649ec05503460f94bcbe70/html5/thumbnails/1.jpg)
Isotope R&D Facility
A proposed addition to the HRIBF driver upgrade
Mike Saltmarsh
HRIBF Users’ Meeting
Nov 13th 2009
![Page 2: Isotope R&D Facility A proposed addition to the HRIBF driver upgrade Mike Saltmarsh HRIBF Users’ Meeting Nov 13 th 2009.](https://reader033.fdocuments.net/reader033/viewer/2022051820/56649ec05503460f94bcbe70/html5/thumbnails/2.jpg)
2 Managed by UT-Battellefor the U.S. Department of Energy Presentation_name
Proposed Isotope Production R&D FacilityNational Context
• There is a national need for a reinvigorated DOE isotope program – selected recommendations from NSAC report
– “Support a sustained research program…. In the production and supply of isotopes….”
– “Investment in new production capabilities”
– “Investment in workforce development”
![Page 3: Isotope R&D Facility A proposed addition to the HRIBF driver upgrade Mike Saltmarsh HRIBF Users’ Meeting Nov 13 th 2009.](https://reader033.fdocuments.net/reader033/viewer/2022051820/56649ec05503460f94bcbe70/html5/thumbnails/3.jpg)
3 Managed by UT-Battellefor the U.S. Department of Energy Presentation_name
Shared use of the C70 is unusually attractive
• A substantial allocation of beam time to the isotope program would be available ( ~ 4500h/yr)
• Little or no impact on the HRIBF mission or flexibility would be incurred
• Concurrent construction of the isotope facility would not significantly impact the C70 upgrade construction
• ORNL already has all the required isotope infrastructure from production through transportation
• The incremental capital cost to the isotope program would be modest (7-10M$)
• The opportunity to share operations costs would benefit both programs
![Page 4: Isotope R&D Facility A proposed addition to the HRIBF driver upgrade Mike Saltmarsh HRIBF Users’ Meeting Nov 13 th 2009.](https://reader033.fdocuments.net/reader033/viewer/2022051820/56649ec05503460f94bcbe70/html5/thumbnails/4.jpg)
4 Managed by UT-Battellefor the U.S. Department of Energy Presentation_name
Elements of the proposed facility
• Dedicated isotope target vault
• Two beamlines from the C70 to the isotope vault
• Two target stations, one a commercially available standard, the other compatible with the BNL/LANL target systems
• Systems for remote transfer of the target modules from target station to transfer cell.
• A transfer cell to package irradiated modules for transfer to the ORNL hot cells
Currently estimated total incremental cost is 7-10 M$
Items in red are part of the isotope facility
![Page 5: Isotope R&D Facility A proposed addition to the HRIBF driver upgrade Mike Saltmarsh HRIBF Users’ Meeting Nov 13 th 2009.](https://reader033.fdocuments.net/reader033/viewer/2022051820/56649ec05503460f94bcbe70/html5/thumbnails/5.jpg)
5 Managed by UT-Battellefor the U.S. Department of Energy Presentation_name
IBA Solid Target System Specifications
• Maximum power dissipation of target assembly (on blank copper target): 12 kW
• Beam profile on target: Gaussian 6 mm FWHM, rotated to uniform flat beam
• Angle of target face to beam: 6 degrees
![Page 6: Isotope R&D Facility A proposed addition to the HRIBF driver upgrade Mike Saltmarsh HRIBF Users’ Meeting Nov 13 th 2009.](https://reader033.fdocuments.net/reader033/viewer/2022051820/56649ec05503460f94bcbe70/html5/thumbnails/6.jpg)
6 Managed by UT-Battellefor the U.S. Department of Energy Presentation_name
Beams available from the C70
Ion Extraction Emin
MeV
Emax
MeV
Imax
A
H- stripping 30 70 750
D- stripping 15 35 50
H2+ ESD - 35 50
α ESD - 70 50
![Page 7: Isotope R&D Facility A proposed addition to the HRIBF driver upgrade Mike Saltmarsh HRIBF Users’ Meeting Nov 13 th 2009.](https://reader033.fdocuments.net/reader033/viewer/2022051820/56649ec05503460f94bcbe70/html5/thumbnails/7.jpg)
7 Managed by UT-Battellefor the U.S. Department of Energy Presentation_name
Important Characteristics of the C70 and it’s anticipated operating regimes
• Very high reliability (~ 95% for commercial C30)– Expectations for the HRIBF operating environment ~ 6600h/yr
of extracted beam availability. 42 weeks, 156 h/week, 7 day operation.
• Dual extraction capability for negative ion beams– HRIBF needs for RIB production ~ 4000 h/yr
– Most RIB production (3000h/yr) requires the full energy proton beam at intensities 50 A and higher
– Allows simultaneous use of 70 MeV protons by isotope program. Independent intensity control (within limits)
• HRIBF operation includes periods of days-weeks when C70 beams not required– 1500-2000 h/yr of dedicated beams (including alphas)
available for the isotope program
![Page 8: Isotope R&D Facility A proposed addition to the HRIBF driver upgrade Mike Saltmarsh HRIBF Users’ Meeting Nov 13 th 2009.](https://reader033.fdocuments.net/reader033/viewer/2022051820/56649ec05503460f94bcbe70/html5/thumbnails/8.jpg)
8 Managed by UT-Battellefor the U.S. Department of Energy Presentation_name
Elements of the Proposed Isotope Program would address many of the needs identified in the NSAC report
• Radioisotope production R&D– New production regimes, eg for 225Ac
– Excitation functions, thick target yields
– Nuclear and radiochemistry
– High power target design
• Radioisotope Production– Research isotopes, eg 211At, 68Ge, 7Be
– Commercial Isotopes, eg 82Sr, 68Ge
• Education and Training
![Page 9: Isotope R&D Facility A proposed addition to the HRIBF driver upgrade Mike Saltmarsh HRIBF Users’ Meeting Nov 13 th 2009.](https://reader033.fdocuments.net/reader033/viewer/2022051820/56649ec05503460f94bcbe70/html5/thumbnails/9.jpg)
9 Managed by UT-Battellefor the U.S. Department of Energy Presentation_name
Production R&D example
• Short-lived (46 m) alpha emitter 213Bi offer great promise for radioimmunotherapy– Attach radionuclide to suitable antibody
– Antibody preferentially attaches to tumor cell
– Radiation delivered within ~100 of tumor cell, not elsewhere
• Supplies are limited, hindering clinical trials– Currently source is 233U - 229 Th (7880y) - 225Ac (10d) as a
generator for 213Bi
– R&D required to investigate other possible production methods
– Funded proposal to look at excitation functions and thick target yields for protons on 230Th and 232Th targets* at HRIBF
![Page 10: Isotope R&D Facility A proposed addition to the HRIBF driver upgrade Mike Saltmarsh HRIBF Users’ Meeting Nov 13 th 2009.](https://reader033.fdocuments.net/reader033/viewer/2022051820/56649ec05503460f94bcbe70/html5/thumbnails/10.jpg)
10 Managed by UT-Battellefor the U.S. Department of Energy Presentation_name
ORNL Infrastructure Available for Education and Training
• Production R&D– Seek University partnerships
• Training programs using ORNL facilities– Production facilities
– Hot cells for target processing
– Radiochemistry labs
– Animal facilities
– Transportation
• Workshops– Workshop on next generation
of radiochemists planned for spring 2010
![Page 11: Isotope R&D Facility A proposed addition to the HRIBF driver upgrade Mike Saltmarsh HRIBF Users’ Meeting Nov 13 th 2009.](https://reader033.fdocuments.net/reader033/viewer/2022051820/56649ec05503460f94bcbe70/html5/thumbnails/11.jpg)
11 Managed by UT-Battellefor the U.S. Department of Energy Presentation_name
Shared use of the C70 is unusually attractive
• A substantial allocation of beam time to the isotope program would be available ( ~ 4500h/yr)
• Little or no impact on the HRIBF mission or flexibility would be incurred
• Concurrent construction of the isotope facility would not significantly impact the C70 upgrade construction
• ORNL already has all the required isotope infrastructure from production through transportation
• The incremental capital cost to the isotope program would be modest (7-10M$)
• The opportunity to share operations costs would benefit both programs